CN105031272A - Preparation for preventing and treating toothache and preparation method of preparation - Google Patents

Preparation for preventing and treating toothache and preparation method of preparation Download PDF

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CN105031272A
CN105031272A CN201510531601.XA CN201510531601A CN105031272A CN 105031272 A CN105031272 A CN 105031272A CN 201510531601 A CN201510531601 A CN 201510531601A CN 105031272 A CN105031272 A CN 105031272A
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folium
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岳源
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岳源
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Abstract

The invention discloses a preparation for preventing and treating toothache, which is mainly prepared from the following raw medicines in parts by weight: 9-16 parts of snow lotus herb, 8-14 parts of woodfordia fruticosa, 7-15 parts of buddha lamp stem and leaf, 6-12 parts of Chinese usnea, 9-14 parts of populus alba leaf, 7-12 parts of corallodiscus flabellatus, 8-13 parts of calabash, 6-15 parts of Chinese starjasmine stem, 9-13 parts of changnienia amoena, 3-6 parts of daphne giraldii, 6-13 parts of Chinese pear-leaved crabapple, 9-15 parts of marginate rockbell herb, 7-14 parts of spinach beet, 6-11 parts of sinopodophyllum polyantha, 8-12 parts of cryptotaenia japonica, 10-14 parts of large-leaved chrysosplenium and 8-15 parts of pinfa raspberry root and leaf. Through summarization of clinical practice for many years, the preparation disclosed by the invention has the effects of clearing away heat and toxic materials as well as eliminating swelling and alleviating pain and has obvious curative effects.

Description

A kind of preparation and preparation method of preventing and treating toothache
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of preparation and preparation method of preventing and treating toothache.
Background technology
Toothache is one of modal symptom of department of stomatology odontopathy, and it shows as red swelling of gingiva, meets caloric stimulation pain, buccal swelling etc.Toothache is caused by gingivitis, periodontitis, decayed tooth or Fractured teeth caused by dental pulp (dental nerve) infection mostly.Toothache belongs to the external reaction of tooth defect, and be likely that the gingiva around dental caries, dental pulp or canine tooth is infected, premolar teeth occurs that slight crack also can cause toothache, is only sometimes that dish bits are stuck in teeth space and cause discomfort.In addition, toothache also may be caused by sinusitis.
Publication No. CN104707000A(application number 201510078446.0) Chinese patent literature disclose a kind of medicament for the treatment of toothache, it is made up by weight of following bulk drugs: Herba Piperris Tonkinensis 280 parts, Canna generalis 250 parts, Radix Silenes Tenuis 230 parts, Radix Rosae Platyphyllae 210 parts, little red numb 200 parts, Bulbus Lilii 230 parts, Flos Bombacis Malabarici 220 parts, Stigma Maydis 230 parts, Fructus Elaeagni Umbellatae 210 parts, Herba Artemisiae Scopariae 210 parts, Fructus Psoraleae 190 parts, Fols Picridis fuscipilosae 150 parts, Ramulus Cinnamomi 250 parts, Herba Adenostemmatis 180 parts, 160 parts, Radix Rubi Tephrodis, Fructus Crataegi 150 parts, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 170 parts, 190 parts, Herba Spirodelae, Fructus Trichosanthis 180 parts, Herba Alternantherae sessilis 200 parts, Fructus Aurantii 200 parts, stone maple medicine 210 parts, Rhizoma Belamcandae 120 parts, Semen Sterculiae Lychnophorae 120 parts, Radix Rhododendri 110 parts and 120 parts, Radix Glycyrrhizae.Publication No. CN104173758A(application number 201410415848.0) Chinese patent literature disclose a kind of Chinese medicine for the treatment of toothache, it is characterized in that making: Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 10 ~ 19% by the crude drug of following percentage by weight, Rhizoma Cimicifugae 9 ~ 13%, Radix Arctii 7 ~ 9%, Herba Asari Forbesii 2 ~ 5%, Herba Odontitis serotinae 9 ~ 11%, Herba Orostachyos 2 ~ 4%, CitrusaurantiumL.Var.amara Engl. 5 ~ 7%, Rhizoma Atractylodis 3 ~ 5%, Fructus Tribuli 4 ~ 6%, Herba Rubi parvifolii 2 ~ 4%, Herba Hedyotis Tenelliflorae 2 ~ 4%, Fructus Viticis 2 ~ 5%, Galla Turcica (Galla Helepensis) 2 ~ 6%, Flos Citri Sarcodactylis 1 ~ 3%, Herba Dendrobii 3 ~ 5%, Calyx Seu Fructus Physalis 4 ~ 7%, above-mentioned 16 taste Chinese medicines are soaked in water, to remove slag after decocting to obtain filtrate.Publication No. CN103463245A(application number 201310442470.9) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of toothache, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Radix Fici tikouae, Herba stellariae mediae, Herba Pteridis Multifidae, Dens Equi, Herba Acalyphae, Clematis filamentosa Dunn, Flos Solani Melongenae, Radix Juglandis, Caulis et Folium Crotalariae Assamicae, Folium Cunninghamiae lanceolatae, Herba rhynchosiae volubilis, Radix Ardisiae Crispae, Rana nigromaculata, Radix Piperis sarmentosi (Herba Piperis Sarmentosi), Radix Rosae Normalis and Radix Delphinii Yunnanensis.
The medicine being used for the treatment of toothache is at present main mainly with antibiotic and analgesic, can only relief of symptoms, thoroughly can not effect a radical cure, long-term taking, cause comparatively major injury to the health of patient, therefore need to develop one Chinese medicine formula safely and effectively.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take preparation and the preparation method of the wide control toothache of safe and applicable.
Technical scheme of the present invention is:
Prevent and treat a preparation for toothache, be prepared from primarily of following bulk drugs, be mass parts: Herba Saussureae Involueratae 9-16; Flos Woodfordiae Fruticosae 8-14; Ramulus et Folium Mussaendae Pubescentis 7-15; Usnea 6-12; Silvery white Folium Populi Pseudo-simonii 9-14; Parmelia saxatilis Ach. 7-12; Pericarpium Lagenariae sicerariae 8-13; Caulis Trachelospermi 6-15; Changuienia amoena Chien 9-13; Daphne giraldii Nitsche 3-6; Fructus Mali Asiaticae 6-13; Herba Wahlenbergiae 9-15; Radix Betae 7-14; CIHUANQIN 6-11; Caulis et folium cryptotaeniae japonicae 8-12; Herba Chrysosplenii Macrophylli 10-14; Radix seu Folium Rubi Pinfaensis 8-15.
Preferred version is, Herba Saussureae Involueratae 11-14; Flos Woodfordiae Fruticosae 10-12; Ramulus et Folium Mussaendae Pubescentis 9-13; Usnea 8-10; Silvery white Folium Populi Pseudo-simonii 10-13; Parmelia saxatilis Ach. 9-10; Pericarpium Lagenariae sicerariae 10-11; Caulis Trachelospermi 8-13; Changuienia amoena Chien 10-12; Daphne giraldii Nitsche 4-5; Fructus Mali Asiaticae 8-11; Herba Wahlenbergiae 11-13; Radix Betae 9-12; CIHUANQIN 7-10; Caulis et folium cryptotaeniae japonicae 9-11; Herba Chrysosplenii Macrophylli 11-13; Radix seu Folium Rubi Pinfaensis 10-13.
More preferably, Herba Saussureae Involueratae 12.5; Flos Woodfordiae Fruticosae 11; Ramulus et Folium Mussaendae Pubescentis 11; Usnea 9; Silvery white Folium Populi Pseudo-simonii 11.5; Parmelia saxatilis Ach. 9.5; Pericarpium Lagenariae sicerariae 10.5; Caulis Trachelospermi 10.5; Changuienia amoena Chien 11; Daphne giraldii Nitsche 4.5; Fructus Mali Asiaticae 9.5; Herba Wahlenbergiae 12; Radix Betae 10.5; CIHUANQIN 8.5; Caulis et folium cryptotaeniae japonicae 10; Herba Chrysosplenii Macrophylli 12; Radix seu Folium Rubi Pinfaensis 11.5.
Described a kind of preparation preventing and treating toothache, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes and sieves together with step (1) (2) (3) made crude drug, makes medicated powder, obtains powder.
Described a kind of preparation method of preventing and treating the preparation powder of toothache, it is (preferred: to pulverize 120-160 mesh sieve that step (4) pulverized 100-180 mesh sieve; Be more preferably: pulverized 140 mesh sieves).
Described a kind of preparation preventing and treating toothache, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then it is (preferred: to pulverize 100-120 mesh sieve to pulverize 80-140 mesh sieve together with step (1) (2) (3) made crude drug; Be more preferably: pulverized 110 mesh sieves), make medicated powder;
(5) by step (4) made medicated powder, add that refined honey water is general makes ball, dry packing, obtain pill.
Described a kind of preparation method of preventing and treating the preparation pill of toothache, the amount that step (5) adds refined honey water is that the 0.8-1.6 of medicated powder quality is doubly (preferred: the amount adding refined honey water is 1.0-1.4 times of medicated powder quality; Be more preferably: the amount adding refined honey water is 1.2 times of medicated powder quality).
Described a kind of preparation preventing and treating toothache, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then it is (preferred: to pulverize 100-120 mesh sieve to pulverize 80-140 mesh sieve together with step (1) (2) (3) made crude drug; Be more preferably: pulverized 110 mesh sieves), gained medicated powder is packed in capsule, obtains capsule.
Described a kind of preparation method of preventing and treating the preparation capsule of toothache, in the every capsules of step (4), contained medicated powder weight is that 0.3-0.6g(is preferred: in every capsules, contained medicated powder weight is 0.4-0.5g; Be more preferably: in every capsules, contained medicated powder weight is 0.45g).
Described a kind of preparation preventing and treating toothache, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes and sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, is crushed to oval tablet dosage form, obtains tablet.
Described a kind of preparation method of preventing and treating the formulation tablet of toothache, it is (preferred: to pulverize 70-90 mesh sieve that step (4) pulverized 60-100 mesh sieve; Be more preferably: pulverized 80 mesh sieves).
A kind of pharmaceutical formulation science of preventing and treating toothache provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, thoroughly cures, and prevents from recurring again;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain;
3, Chinese crude drug selected by the present invention, safety has no side effect, and is applicable to the crowd of Different age group.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1prevent and treat a preparation for toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Saussureae Involueratae 9 parts, Flos Woodfordiae Fruticosae 8 parts, Ramulus et Folium Mussaendae Pubescentis 7 parts, Usnea 6 parts, silvery white Folium Populi Pseudo-simonii 9 parts, Parmelia saxatilis Ach. 7 parts, Pericarpium Lagenariae sicerariae 8 parts, Caulis Trachelospermi 6 parts, Changuienia amoena Chien 9 parts, Daphne giraldii Nitsche 3 parts, Fructus Mali Asiaticae 6 parts, Herba Wahlenbergiae 9 Fen , Radix Betae 7 parts, CIHUANQIN 6 parts, Caulis et folium cryptotaeniae japonicae 8 parts, Herba Chrysosplenii Macrophylli 10 parts, Radix seu Folium Rubi Pinfaensis 8 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation powder of toothache is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution of 20% of boiled crude drug quality 6 times, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes 140 mesh sieves together with step (1) (2) (3) made crude drug, makes medicated powder, obtains powder.
embodiment 2prevent and treat a preparation for toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Saussureae Involueratae 16 parts, Flos Woodfordiae Fruticosae 14 parts, Ramulus et Folium Mussaendae Pubescentis 15 parts, Usnea 12 parts, silvery white Folium Populi Pseudo-simonii 14 parts, Parmelia saxatilis Ach. 12 parts, Pericarpium Lagenariae sicerariae 13 parts, Caulis Trachelospermi 15 parts, Changuienia amoena Chien 13 parts, Daphne giraldii Nitsche 6 parts, Fructus Mali Asiaticae 13 parts, Herba Wahlenbergiae 15 Fen , Radix Betae 14 parts, CIHUANQIN 11 parts, Caulis et folium cryptotaeniae japonicae 12 parts, Herba Chrysosplenii Macrophylli 14 parts, Radix seu Folium Rubi Pinfaensis 15 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation pill of toothache is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution of 20% of boiled crude drug quality 6 times, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes 110 mesh sieves together with step (1) (2) (3) made crude drug, makes medicated powder;
(5) by step (4) made medicated powder, add that the refined honey water of medicated powder quality 1.2 times is general makes ball, dry packing, obtain pill.
Model case: xxx, women, 52 years old.Main suit: patient has a toothache 3 years, backteeth rest pain on both sides, responsive for caloric stimulation, during sleeping at night, the pain increased, impact sleep and having a rest, and once took analgesic, can only the respite state of an illness, and toothache outbreak is got up, and cannot take food, patient is very painful.
Take this example gained pill, each 2-3 grain, warm boiled water, one day twice, within seven days, be a course for the treatment of, after patient takes a course for the treatment of, pain symptom has obvious alleviation, after continuing to take two courses for the treatment of, touch not bitterly, caloric stimulation is insensitive, follows up a case by regular visits in 1 year, do not recur after drug withdrawal.
embodiment 3prevent and treat a preparation for toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Saussureae Involueratae 11 parts, Flos Woodfordiae Fruticosae 10 parts, Ramulus et Folium Mussaendae Pubescentis 9 parts, Usnea 8 parts, silvery white Folium Populi Pseudo-simonii 10 parts, Parmelia saxatilis Ach. 9 parts, Pericarpium Lagenariae sicerariae 10 parts, Caulis Trachelospermi 8 parts, Changuienia amoena Chien 10 parts, Daphne giraldii Nitsche 4 parts, Fructus Mali Asiaticae 8 parts, Herba Wahlenbergiae 11 Fen , Radix Betae 9 parts, CIHUANQIN 7 parts, Caulis et folium cryptotaeniae japonicae 9 parts, Herba Chrysosplenii Macrophylli 11 parts, Radix seu Folium Rubi Pinfaensis 10 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation capsule of toothache is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution of 20% of boiled crude drug quality 6 times, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes 110 mesh sieves together with step (1) (2) (3) made crude drug, is packed in capsule by gained medicated powder, and in every capsules, contained medicated powder weight is 0.45g, obtains capsule.
Model case: xxx, male, 24 years old.Medical history: patient obtains repeatability toothache and has half a year, meets acid, hot and cold stimulation, toothache outbreak, in paroxysmal, dare not touch, time serious, with facial swelling and ear's radiated pain, through examination in hospital, be diagnosed as acute toothache.
Recommending to take this example gained capsule, each 2-3 grain, warm boiled water, one day twice through people, seven days is a course for the treatment of, after patient takes a course for the treatment of, pain relief, facial swelling disappears, after taking two courses for the treatment of, uncomfortable disease is all eliminated, and patient fully recovers, and follows up a case by regular visits to after half a year, and toothache is not repeatedly.
embodiment 4prevent and treat a preparation for toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Saussureae Involueratae 14 parts, Flos Woodfordiae Fruticosae 12 parts, Ramulus et Folium Mussaendae Pubescentis 13 parts, Usnea 10 parts, silvery white Folium Populi Pseudo-simonii 13 parts, Parmelia saxatilis Ach. 10 parts, Pericarpium Lagenariae sicerariae 11 parts, Caulis Trachelospermi 13 parts, Changuienia amoena Chien 12 parts, Daphne giraldii Nitsche 5 parts, Fructus Mali Asiaticae 11 parts, Herba Wahlenbergiae 13 Fen , Radix Betae 12 parts, CIHUANQIN 10 parts, Caulis et folium cryptotaeniae japonicae 11 parts, Herba Chrysosplenii Macrophylli 13 parts, Radix seu Folium Rubi Pinfaensis 13 parts.Above-mentioned a kind of preparation method of preventing and treating the formulation tablet of toothache is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution of 20% of boiled crude drug quality 6 times, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes 80 mesh sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, is crushed to oval tablet dosage form, obtains tablet.
Model case: xxx, women, 32 years old.Main suit: toothache, red and swollen, gingival hemorrhage; Medical history: patient ate barbecue before three days together with friend, after getting up next day, realizes gingival hemorrhage, to have a meal dental pain when chewing, rear aggravation, toothache is outbreak in paroxysmal, it is heavy when time is light, and with uncomfortable diseases such as headache, thirsty, halitosis, check through doctor, large dry stool, red tongue, yellow fur, slippery and rapid pulse, is diagnosed as toothache due to stomach-fire.
Listen people to introduce and take this example gained tablet, each 2-3 sheet, warm boiled water, one day twice, within seven days, be a course for the treatment of, after patient takes five days, toothache alleviates, and after continuing to take a course for the treatment of, without other uncomfortable diseases, patient's self-induction is fully recovered, and check physical recovery is normal.
embodiment 5prevent and treat a preparation for toothache, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Saussureae Involueratae 12.5 parts, Flos Woodfordiae Fruticosae 11 parts, Ramulus et Folium Mussaendae Pubescentis 11 parts, Usnea 9 parts, silvery white Folium Populi Pseudo-simonii 11.5 parts, Parmelia saxatilis Ach. 9.5 parts, Pericarpium Lagenariae sicerariae 10.5 parts, Caulis Trachelospermi 10.5 parts, Changuienia amoena Chien 11 parts, Daphne giraldii Nitsche 4.5 parts, Fructus Mali Asiaticae 9.5 parts, Herba Wahlenbergiae 12 Fen , Radix Betae 10.5 parts, CIHUANQIN 8.5 parts, Caulis et folium cryptotaeniae japonicae 10 parts, Herba Chrysosplenii Macrophylli 12 parts, Radix seu Folium Rubi Pinfaensis 11.5 parts.Above-mentioned a kind of preparation method of preventing and treating the preparation powder of toothache is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution of 20% of boiled crude drug quality 6 times, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 15 minutes, takes out, pulverizes;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes 140 mesh sieves together with step (1) (2) (3) made crude drug, makes medicated powder, obtains powder.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Saussureae Involueratae: base is former: be the whole herb with root of feverfew Saussurea laniceps, the bent Herba Saussureae Involueratae of Mus, Saussurea medusa Maxim., Essential Oil flower, Folium Querci dentatae Herba Saussureae Involueratae.Nature and flavor: sweet in the mouth; Micro-hardship.Gui Jing: return tripe; Kidney channel.Function cures mainly: warming the kidney to invigorate YANG; Regulating menstruation, hemostasis.Main sexual impotence; Soreness of the waist and knees; Under woman's subband, menoxenia; Rheumatic Bi syndrome; Traumatic hemorrhage.
Flos Woodfordiae Fruticosae: base is former: be root, the flower of Lythraceae plant Flos Woodfordiae Fruticosae.Nature and flavor: taste is micro-sweet, puckery, warm in nature.Function cures mainly: grate hemostasis of living, relaxing muscles and tendons and activating QI and blood in the collateral.Main dysmenorrhea, amenorrhea, metrorrhagia, epistaxis, hemoptysis, discharging fresh blood stool, dysentery, rheumatic arthralgia, lumbar muscle strain, traumatic injury.
Ramulus et Folium Mussaendae Pubescentis: base is former: be the stem and leaf of dicotyledon medicine Maguireothamnus speciosus hair Radix Mussaendae.Nature and flavor: sweet micro-hardship; Cool.Gui Jing: bladder; Lung; Large intestine channel.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main flu; Heatstroke; Heating; Cough; Laryngopharynx swelling and pain; Have loose bowels; Dysentery; Oedema due to nephritis; Damp and hot dysuria, skin infection pus swells; Venom.
Usnea: base is former: be the thallus of the flat plant Usnea Longissima of Usnea, ring crack Usnea.Nature and flavor: sweet; Bitter; Property is put down.Gui Jing: the heart; Kidney; Lung meridian.Function cures mainly: expelling phlegm for arresting cough; Heat-clearing and toxic substances removing; Eliminating dampness and dredging channels; Blood-arresting catamenia-regulating; Anthelmintic.。Main expectorant hot temperature malaria; Cough with asthma; Pulmonary tuberculosis; Headache; Conjunctival congestion nebula, carbuncle sore tumefacting virus; Scrofula; Acute mastitis; Burn and scald; Venom, pathogenic wind-warm arthralgia pain, traumatic injury, fracture; Traumatic hemorrhage, spits blood; Have blood in stool; Metrorrhagia, menoxenia; Leucorrhea; Ascariasis; Schistosomicide.
Silvery white Folium Populi Pseudo-simonii: base is former: be the leaf of Salicaceae poplar white poplar.Function cures mainly: relieving cough and asthma, removing heat-phlegm.
Parmelia saxatilis Ach.: base is former: be the thallus of Parmeliaceae phytobezoar prunus mume (sieb.) sieb.et zucc. clothing.Nature and flavor: sweet; Property is put down.Gui Jing: liver; Kidney channel.Function cures mainly: invigrating kidney; Improving eyesight; Hemostasis, eliminating damp, detoxifying.。Main blurred vision; Lumbocrural pain; Spit blood; Metrorrhagia jaundice, skin ulcer tinea.
Pericarpium Lagenariae sicerariae: base is former: be the fruit of cucurbitaceous plant calabash, calabash courd.Nature and flavor: sweet in the mouth; Light; Property is put down.Gui Jing: return lung; Spleen; Kidney channel.Function cures mainly: diuretic; Detumescence; Logical woods; Eliminating stagnation.Main edema; Ascites; Jaundice; Quench one's thirst; Gonorrhea; Carbuncle.
Caulis Trachelospermi: base is former: be stem, the leaf of apocynaceae plant trachelospermum jasminoide.Chemical analysis: stem is containing arctigenin, tracheloside, matairesinoside, nortracheloside, dambonitol, cupreol glycoside, cymarose etc.Nature and flavor: bitter, cool.Gui Jing: enter liver, kidney channel.Function cures mainly: dispel the wind, dredging collateral, hemostasis, repercussive.Dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins, carbuncle, sore throat, spits blood, traumatic injury, disease that postpartum lochia can't go.
Changuienia amoena Chien: base is former: be pseudobulb and the herb of orchid Herba Changnieniae amoenae.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat clearing away; Removing heat from blood; Removing toxic substances.Main cough; Sputum mixed with blood; Furuncle furuncle.
Daphne giraldii Nitsche: base is former: be root bark and the peel of stem of Isolated From Thymelaeaceae Species Daphne Giraldii Nitsche.Nature and flavor: bitter, pungent, temperature.Slightly poisonous.Function cures mainly: dispelling wind and removing obstruction in the collateral, stasis-dispelling and pain-killing.For headache, toothache, rheumatic arthritis, traumatic injury, stomachache, pain in the hepatic region.
Fructus Mali Asiaticae: base is former: be the fruit of rosaceous plant premium.Nature and flavor: sour, sweet; Temperature; Nontoxic.Gui Jing: the heart; Liver; Lung meridian.Function cures mainly: expel flatulence and relieve chest stuffiness, promoting the production of body fluid to quench thirst, relieving pain by regulating middle-JIAO.Main phlegm retention food stagnation, chest and diaphragm painful abdominal mass plug, quenches one's thirst, cholera, stomachache of vomiting and diarrhoea, dysentery.
Herba Wahlenbergiae: base is former: be root or the herb of Campanulaceae Radix Wahlenbergiae Marginatae.Nature and flavor: sweet in the mouth; Micro-hardship; Property is put down.Gui Jing: return spleen; Lung meridian.Function cures mainly: replenishing QI to invigorate the spleen; Eliminating phlegm and stopping cough; Hemostasis.Main deficient impairment caused by overstrain; Spontaneous perspiration; Night sweat; Infantile malnutrition; Women leucorrhea; Flu; Cough; Epistaxis; Malaria; Scrofula.
Radix Betae: base is former: be stem, the leaf of multitude Zhong Zhi Wu Radix Betae.Nature and flavor: sweet; Bitter; Cold in nature.Gui Jing: lung; Kidney; Large intestine channel.Function cures mainly: heat-clearing and toxic substances removing; Clots absorbing stops blooding.Row calentura time main; Hemorrhoid; Measles is sent out not smooth thoroughly; Spit blood; Pyretic toxicity dysentery; Amenorrhea; Stranguria with turbid discharge; Carbuncle; Traumatic injury; Snakeworm hinders.
CIHUANQIN: base is former: be the Herb of Berberidaceae plant mahonia fargesii Takeda.Nature and flavor: bitter; Cold.Function cures mainly: heat clearing away; Dampness; Removing toxic substances.Main pulmonary tuberculosis cough spitting of blood; Jaundice; Damp-heat diarrhea; Dysentery; Conjunctival congestion and swelling pain; Eczema.
Caulis et folium cryptotaeniae japonicae: base is former: be the stem and leaf of samphire Caulis et folium cryptotaeniae japonicae.Nature and flavor: acrid in the mouth; Bitter; Property is put down.Function cures mainly: dispelling wind stopping cough; Eliminating damp, detoxifying; Blood-activating analgetic.Main cold cough; Lung abscess; Drench pain; Hernia; Menoxenia; Acute toothache; Cataract; Carbuncle skin ulcer swells; Skin pruritus; Treating swelling and pain by traumatic injury; Snake bite and insect sting.
Herba Chrysosplenii Macrophylli: base is former: be the herb of saxifragaceae plant great Ye gold waist.Nature and flavor: bitter in the mouth, puckery, cold in nature.Function cures mainly: heat-clearing and toxic substances removing, cough-relieving, leukorrhagia stopping, convergence granulation promoting.Main ecthyma; Scald.
Radix seu Folium Rubi Pinfaensis: base is former: be the root of the red hair Fructus Rubi corchorifolii Immaturus of rosaceous plant.Chemical analysis: root is containing 2a, 3 β, 23a-triacetoxyl group-19a-hydroxyl-12-Usu alkene-28 β acid-methyl ester.Nature and flavor: acid is salty; Cool.Gui Jing: liver; Kidney channel.Function cures mainly: cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment.Main heat in blood is spitted blood, and hematuria, has blood in stool, metrorrhagia, rheumatic arthritis, scrofula, eczema, leukorrhagia.
test example 1a kind of clinical practice preventing and treating the preparation (embodiment 5) of toothache of gained of the present invention:
Choose crowd: in April ,-2015 in May, 2014, according to medical case history, three hospitals' screening patient with toothache 331 examples, age 10-60 year, 35.8 ± 2.6 years old mean age, the course of disease 2 days-3 years, wherein male patient 168 example, female patient 163 example.
Before test, patient is divided into two groups at random, experimental group 226 example and matched group 105 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 2-3g, one day twice, warm boiled water, within seven days, is a course for the treatment of; Matched group takes other conventional medicines (Fu Fang Ya Tong Ding, Yazhoukang, ibuprofen etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: toothache transference cure, and chance caloric stimulation is without exception; (2) effective: toothache transference cure, meet caloric stimulation or still have swelling and pain sense when chewing hard object; (3) effective: toothache symptom takes a turn for the better, meet caloric stimulation and when chewing hard object, pain increases the weight of; (4) invalid: before and after treatment, symptom is not improved or increases the weight of.Total effective rate=cure rate+obvious effective rate
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as follows:
Toothache transference cure, meet the N/R patient of caloric stimulation and have 159 examples (70.4%), toothache transference cure, meet caloric stimulation or when chewing hard object, still have the patient of swelling and pain sense to have 45 examples (19.9%), toothache symptom takes a turn for the better, chance caloric stimulation and the patient that when chewing hard object, pain increases the weight of have 18 examples (8.0%), and the total effective rate of known experimental group is 90.3%.The patient cured in matched group has 52 examples (49.5%), and effective patient has 23 examples (21.9%), and effective patient is 14 examples (13.3%), and the total effective rate of matched group is 71.4%.
The Chinese medicine used in the present invention, comprise the Herba Saussureae Involueratae of regulating menstruation, hemostasis, the Flos Woodfordiae Fruticosae of relaxing muscles and tendons and activating QI and blood in the collateral, the Ramulus et Folium Mussaendae Pubescentis of clearing away heat-damp and promoting diuresis, the Usnea of heat-clearing and toxic substances removing, Changuienia amoena Chien, Radix Betae, Herba Chrysosplenii Macrophylli, the silvery white Folium Populi Pseudo-simonii of removing heat-phlegm, the Parmelia saxatilis Ach. of invigrating kidney, the Pericarpium Lagenariae sicerariae of inducing diuresis to remove edema, the Caulis Trachelospermi of dispelling wind and removing obstruction in the collateral, the Daphne giraldii Nitsche of stasis-dispelling and pain-killing, the Fructus Mali Asiaticae of relieving pain by regulating middle-JIAO, the Herba Wahlenbergiae of replenishing QI to invigorate the spleen, the CIHUANQIN of dampness removing toxic substances, the Caulis et folium cryptotaeniae japonicae of blood-activating analgetic, the Radix seu Folium Rubi Pinfaensis of cooling blood for hemostasis, multiple medical material synergism, plays effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. prevent and treat a preparation for toothache, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Herba Saussureae Involueratae 9-16; Flos Woodfordiae Fruticosae 8-14; Ramulus et Folium Mussaendae Pubescentis 7-15; Usnea 6-12; Silvery white Folium Populi Pseudo-simonii 9-14; Parmelia saxatilis Ach. 7-12; Pericarpium Lagenariae sicerariae 8-13; Caulis Trachelospermi 6-15; Changuienia amoena Chien 9-13; Daphne giraldii Nitsche 3-6; Fructus Mali Asiaticae 6-13; Herba Wahlenbergiae 9-15; Radix Betae 7-14; CIHUANQIN 6-11; Caulis et folium cryptotaeniae japonicae 8-12; Herba Chrysosplenii Macrophylli 10-14; Radix seu Folium Rubi Pinfaensis 8-15.
2. a kind of preparation preventing and treating toothache as claimed in claim 1, is characterized in that, Herba Saussureae Involueratae 11-14; Flos Woodfordiae Fruticosae 10-12; Ramulus et Folium Mussaendae Pubescentis 9-13; Usnea 8-10; Silvery white Folium Populi Pseudo-simonii 10-13; Parmelia saxatilis Ach. 9-10; Pericarpium Lagenariae sicerariae 10-11; Caulis Trachelospermi 8-13; Changuienia amoena Chien 10-12; Daphne giraldii Nitsche 4-5; Fructus Mali Asiaticae 8-11; Herba Wahlenbergiae 11-13; Radix Betae 9-12; CIHUANQIN 7-10; Caulis et folium cryptotaeniae japonicae 9-11; Herba Chrysosplenii Macrophylli 11-13; Radix seu Folium Rubi Pinfaensis 10-13(is preferably: Herba Saussureae Involueratae 12.5; Flos Woodfordiae Fruticosae 11; Ramulus et Folium Mussaendae Pubescentis 11; Usnea 9; Silvery white Folium Populi Pseudo-simonii 11.5; Parmelia saxatilis Ach. 9.5; Pericarpium Lagenariae sicerariae 10.5; Caulis Trachelospermi 10.5; Changuienia amoena Chien 11; Daphne giraldii Nitsche 4.5; Fructus Mali Asiaticae 9.5; Herba Wahlenbergiae 12; Radix Betae 10.5; CIHUANQIN 8.5; Caulis et folium cryptotaeniae japonicae 10; Herba Chrysosplenii Macrophylli 12; Radix seu Folium Rubi Pinfaensis 11.5).
3. a kind of preparation preventing and treating toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes and sieves together with step (1) (2) (3) made crude drug, makes medicated powder, obtains powder.
4. a kind of preparation method of preventing and treating the preparation powder of toothache as claimed in claim 3, is characterized in that, it is (preferred: to pulverize 120-160 mesh sieve that step (4) pulverized 100-180 mesh sieve; Be more preferably: pulverized 140 mesh sieves).
5. a kind of preparation preventing and treating toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then it is (preferred: to pulverize 100-120 mesh sieve to pulverize 80-140 mesh sieve together with step (1) (2) (3) made crude drug; Be more preferably: pulverized 110 mesh sieves), make medicated powder;
(5) by step (4) made medicated powder, add that refined honey water is general makes ball, dry packing, obtain pill.
6. a kind of preparation method of preventing and treating the preparation pill of toothache as claimed in claim 5, is characterized in that, the amount that step (5) adds refined honey water is that the 0.8-1.6 of medicated powder quality is doubly (preferred: the amount adding refined honey water is 1.0-1.4 times of medicated powder quality; Be more preferably: the amount adding refined honey water is 1.2 times of medicated powder quality).
7. a kind of preparation preventing and treating toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then it is (preferred: to pulverize 100-120 mesh sieve to pulverize 80-140 mesh sieve together with step (1) (2) (3) made crude drug; Be more preferably: pulverized 110 mesh sieves), gained medicated powder is packed in capsule, obtains capsule.
8. a kind of preparation method of preventing and treating the preparation capsule of toothache as claimed in claim 7, is characterized in that, in the every capsules of step (4), contained medicated powder weight is that 0.3-0.6g(is preferred: in every capsules, contained medicated powder weight is 0.4-0.5g; Be more preferably: in every capsules, contained medicated powder weight is 0.45g).
9. a kind of preparation preventing and treating toothache as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Ramulus et Folium Mussaendae Pubescentis, Usnea, silvery white Folium Populi Pseudo-simonii, Parmelia saxatilis Ach., Radix Betae and Caulis et folium cryptotaeniae japonicae to clean, be placed in frying pan, slow fire stir-fries sallow to surface, takes out, pulverizes, add the alcoholic solution (preferred: the alcoholic solution adding 20% of boiled crude drug quality 6 times) of boiled crude drug quality 5-7 times 20%, heating is boiled to boiling, continues 15 minutes, obtains filtrate after filtration, concentrated filtrate, to thick paste, is dried;
(2) get Herba Saussureae Involueratae, Flos Woodfordiae Fruticosae, Caulis Trachelospermi, Daphne giraldii Nitsche, Herba Wahlenbergiae, CIHUANQIN and Radix seu Folium Rubi Pinfaensis remove impurity to clean, cut into slices, be placed in the vinegar that boils and infiltrate 3 minutes, take out, put into hot pot, intense fire is fried to surface burned black, cools rear taking-up;
(3) get Pericarpium Lagenariae sicerariae and Fructus Mali Asiaticae removing impurity, be placed in container, add refined honey water infiltration 5 minutes, be placed in by container in steamer, water proof heats 10-20 minute (preferably: water proof heating 12-18 minute; Be more preferably: water proof heats 15 minutes), take out, pulverize;
(4) Changuienia amoena Chien and Herba Chrysosplenii Macrophylli are cleaned, slow fire is dried, then pulverizes and sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, is crushed to oval tablet dosage form, obtains tablet.
10. a kind of preparation method of preventing and treating the formulation tablet of toothache as claimed in claim 9, is characterized in that, it is (preferred: to pulverize 70-90 mesh sieve that step (4) pulverized 60-100 mesh sieve; Be more preferably: pulverized 80 mesh sieves).
CN201510531601.XA 2015-08-27 2015-08-27 Preparation for preventing and treating toothache and preparation method of preparation Pending CN105031272A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060019269A1 (en) * 2002-10-17 2006-01-26 Decode Genetics, Inc. Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
CN104524170A (en) * 2014-12-26 2015-04-22 丁鸿磊 Traditional Chinese medicine for treating wind-fire toothache and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060019269A1 (en) * 2002-10-17 2006-01-26 Decode Genetics, Inc. Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
CN104524170A (en) * 2014-12-26 2015-04-22 丁鸿磊 Traditional Chinese medicine for treating wind-fire toothache and preparation method thereof

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