CN105078828B - A kind of plants antimicrobial compound hand cleanser and preparation method thereof - Google Patents
A kind of plants antimicrobial compound hand cleanser and preparation method thereof Download PDFInfo
- Publication number
- CN105078828B CN105078828B CN201510534576.0A CN201510534576A CN105078828B CN 105078828 B CN105078828 B CN 105078828B CN 201510534576 A CN201510534576 A CN 201510534576A CN 105078828 B CN105078828 B CN 105078828B
- Authority
- CN
- China
- Prior art keywords
- hand cleanser
- antimicrobial compound
- kuh
- plants antimicrobial
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The present invention relates to a kind of plants antimicrobial compound hand cleanser and preparation method thereof, the hand cleanser is mainly made of rhizoma Gastrodiae, P-Cymene, radix scutellariae, frutus cnidii, kuh-seng etc., has significant antibacterial, clean effect, to no skin irritation, and moisture of skin can be supplemented, is adapted to long-time service.
Description
Technical field
The invention belongs to daily washing product technical field, and in particular to a kind of plants antimicrobial compound hand cleanser, at the same time also
Provide the preparation method of the hand cleanser.
Background technology
As the improvement of people's living standards, the generation of the epidemic situation such as Severe Acute Respiratory Syndromes, " bird flu ", makes the consumer of China more
Focus on personal hygiene, the keyword of washing one's hands such as " frequently washing one's hands " and " sterilization " is gradually rooted in the hearts of the people, in China's a very long time in past,
People are washed one's hands using perfumed soap always, perfumed soap strong detergency, but can make dry skin, tarnish after washing one's hands, especially easily contamination
Dirt on hand and bacterium, cause secondary pollution, therefore mass consumption idea is gradually converted into using hand cleanser as use of washing one's hands
The substitute of product, hand cleanser market development is rapid, its utilization rate is up to 25% at present, and hand cleanser market is gradually improved, people couple
In the requirement of hand cleanser the functional form hand cleanser such as antibacterial, moisturizing is gradually developed into from simple decontamination.
Disinfection hand cleanser is one kind of occupancy volume maximum in the special hand cleanser of existing market, and most of hand cleanser exist
Effect in terms of disinfection is more satisfactory, but the disinfection class functional component in hand cleanser is mostly chemical synthesis, to skin
Irritation it is larger, long-time service be easy to cause hand skin it is dry, it is coarse and chap.Hand cleanser of the present invention is carried with natural traditional Chinese medicine
It is sterilization component to take thing, while ensureing that hand cleanser is significantly sterilized, decontamination is active, reduces skin irritation, while hand cleanser
In contain a variety of skin care ingredients, supplement moisture needed for skin, the moist feeling of rear skin is washed in enhancing.
The content of the invention
The present invention is intended to provide a kind of plants antimicrobial compound medicine, contains a variety of middle medicines with notable antibacterial activity
Matter, while good cleaning action is ensured, has lasting anti-microbial property, and supplements moisture needed for skin, is adapted to long-term
Use.
Invention further provides the preparation method of plants antimicrobial compound medicine hand cleanser, suitable for industrialized production.
A kind of plants antimicrobial compound medicine of the present invention, it is characterised in that mainly by the raw material system of following parts by weight
Into：
0.5 ~ 5 part of rhizoma Gastrodiae, 0.01 ~ 0.1 part of P-Cymene, 0.5 ~ 5 part of radix scutellariae, 0.1 ~ 1 part of frutus cnidii, kuh-seng 0.1 ~
1 part.
A kind of preparation method of plants antimicrobial compound medicine hand cleanser of the present invention, comprises the following steps：
Radix scutellariae, rhizoma Gastrodiae, frutus cnidii, kuh-seng are weighed in proportion, add 10~50 parts of deionized waters, 2~5h of refluxing extraction, weight
Multiple extraction once, merges extracting solution twice, add P-Cymene, N- acyl glutamic acids, vitamin E, aloe, glycerine, lanolin,
SDS, EDTA-2Na, sodium carboxymethylcellulose, sodium chloride, sodium citrate, citric acid, after stirring and evenly mixing adjust pH to 5.0~
7.0, stand, treat that foam is wholly absent, liquid is transparent to obtain the final product.
Fang Xie：Rhizoma Gastrodiae is sweet, flat, for dizziness of having a headache, extremity numbness, child convulsion, epilepsy clonus, lockjaw；Radix scutellariae
It is bitter, cold, it is mainly used for heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis；P-Cymene has desinsection hemostasis, antiallergic activity；Snake
Machine tool is warm-natured, and for impotence, Gong Leng, morbid leucorrhoea duye, arthritis with fixed pain caused by dampness pain in the back, controls eczema of vulva, married woman's pruritus vulvae, trichomonas vaginitis outside；
Kuh-seng is used for hot dysentery, has blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, mange leprosy；Control outside
Trichomonas vaginitis.The present invention relates to hand cleanser using rhizoma Gastrodiae, P-Cymene as monarch drug in a prescription, using radix scutellariae as ministerial drug, help with frutus cnidii, hardship
The Chinese medicines such as ginseng, prepare, and all medicine collaborations, ensure that hand cleanser has significant sterilization, skin-care effect.
The positive effect of the present invention is：Using natural traditional Chinese medicine antimicrobial component, skin irritation is reduced, while in hand cleanser
A variety of skin care ingredients such as glycerine, vitamin E, aloe are added, and remain nutritional ingredient in Chinese medical extract to greatest extent, are made
Product has effects that good anti-bacteria wet keeping while cleaning action is played.
Embodiment
In order to be best understood from the technology contents of the present invention, the present invention is carried out below by specific implementation case detailed
Thin description.
Case study on implementation 1
0.5kg radix scutellariaes, 0.5kg rhizoma Gastrodiaes, 0.1kg frutus cnidiis, 0.1kg kuh-sengs are weighed, adds 20kg deionized waters, reflux carries
3h is taken, repeats extraction once, merges extracting solution twice, adds 0.02kg P-Cymenes, 0.5kg N- acyl glutamic acids, 0.1kg
Vitamin E, 0.5kg aloes, 1.0kg glycerine, 1.0kg lanolin, 0.2kg SDS, 0.1kg EDTA-2Na, 0.1kg carboxymethyls
Sodium cellulosate, 0.05kg sodium chloride, 0.1kg sodium citrates, adjust pH to 6.0 after stirring and evenly mixing, stand, treat that foam disappears completely
Lose, liquid is transparent to obtain the final product.
Case study on implementation 2
3.0kg radix scutellariaes, 3.0kg rhizoma Gastrodiaes, 1.0kg frutus cnidiis, 1.0kg kuh-sengs are weighed, adds 50kg deionized waters, reflux carries
3h is taken, repeats extraction once, merges extracting solution twice, adds 0.5kg P-Cymenes, 1kg N- acyl glutamic acids, 0.2kg dimension lifes
Plain E, 1.0kg aloe, 3.0kg glycerine, 2.0kg lanolin, 0.2kg SDS, 0.5kg EDTA-2Na, 0.8kg carboxymethyl celluloses
Plain sodium, 0.2kg sodium chloride, 0.3kg sodium citrates, adjust pH to 6.0 after stirring and evenly mixing, stand, treat that foam is wholly absent, liquid
It is transparent to obtain the final product.
Case study on implementation 3
5.0kg radix scutellariaes, 3.0kg rhizoma Gastrodiaes, 0.5kg frutus cnidiis, 0.5kg kuh-sengs are weighed, adds 40kg deionized waters, reflux carries
5h is taken, repeats extraction once, merges extracting solution twice, adds 0.8kg P-Cymenes, 0.5kg N- acyl glutamic acids, 0.3kg dimensions
Raw element E, 0.4kg aloe, 2.0kg glycerine, 4.0kg lanolin, 0.15kg SDS, 0.3kg EDTA-2Na, 0.8kg carboxymethyls are fine
The plain sodium of dimension, 0.4kg sodium chloride, 0.4kg sodium citrates, adjust pH to 6.0, stand, treat that foam is wholly absent, liquid after stirring and evenly mixing
Body is transparent to obtain the final product.
Case study on implementation 4
2.0kg radix scutellariaes, 4.0kg rhizoma Gastrodiaes, 0.5kg frutus cnidiis, 0.1kg kuh-sengs are weighed, adds 50kg deionized waters, reflux carries
5h is taken, repeats extraction once, merges extracting solution twice, adds 0.5kg P-Cymenes, 0.4kg N- acyl glutamic acids, 0.2kg dimensions
Raw element E, 1.0kg aloe, 4.0kg glycerine, 2.0kg lanolin, 0.4kg SDS, 0.2kg EDTA-2Na, 1.0kg carboxymethyls are fine
The plain sodium of dimension, 0.3kg sodium chloride, 0.5kg sodium citrates, adjust pH to 6.0, stand, treat that foam is wholly absent, liquid after stirring and evenly mixing
Body is transparent to obtain the final product.
Case study on implementation 5
5.0kg radix scutellariaes, 0.5kg rhizoma Gastrodiaes, 0.3kg frutus cnidiis, 0.3kg kuh-sengs are weighed, adds 40kg deionized waters, reflux carries
4h is taken, repeats extraction once, merges extracting solution twice, adds 0.2kg P-Cymenes, 0.5kg N- acyl glutamic acids, 0.5kg dimensions
Raw element E, 2.0kg aloe, 2.0kg glycerine, 1.5kg lanolin, 0.3kg SDS, 0.3kg EDTA-2Na, 0.9kg carboxymethyls are fine
The plain sodium of dimension, 0.4kg sodium chloride, 0.2kg sodium citrates, adjust pH to 6.0, stand, treat that foam is wholly absent, liquid after stirring and evenly mixing
Body is transparent to obtain the final product.
Tests below example shows the positive effect of the present invention：
The measure of foaming power
Using concussion method measure：Hand cleanser 0.01ml prepared by 1 ~ embodiment of embodiment 5 is added in colorimetric cylinder, then is added
Enter 10ml distilled water, cover lid, shake 50 times（It is as consistent as possible to shake direction, speed, intensity etc.）, lid is removed, is added
Enter the water of 10ml, foam on colorimetric tube wall is swept away, record the height of foam and foam is corrupted to original mid-height when institute
Take time, using foam height measuring as hand cleanser frothing capacity, required time when being corrupted to original mid-height with foam
Characterize the stability of foam.
1 hand cleanser foam height of form and foam stability detection
Hand cleanser has preferable foams performance in 5 groups of case study on implementation it can be seen from experimental result, and its foam has
Good stability.
Stability Determination of the present invention
Hand cleanser prepared by 1 ~ embodiment of Example 5 places 24h in -5 DEG C of refrigerator, takes out and is seen when recovering to room temperature
Examine, whether there is precipitation and metachromatism occurs;24h is placed in 40 DEG C of incubator, takes out and is observed when recovering to room temperature, had
Free from extraneous odour, layering and metachromatism.
2 hand cleanser Detection of Stability of form
After hand cleanser in 5 groups of case study on implementation it can be seen from experimental result places 24h in -5 DEG C and 40 DEG C of incubators,
Occur without precipitation, discoloration, lamination, sample homogeneous transparent, has good stability.
Bactericidal activity detection of the present invention.
According to Ministry of Health of the People's Republic of China《Disinfection technology standard》（Version in 2002）Regulation carries out 5 kinds of case study on implementation pair
Escherichia coli（ATCC25922）, golden staphylococci（ATCC 6538）, Candida albicans（ATCC 10231）Bacteriostatic activity detects.
After hand cleanser effect 2min in 5 groups of case study on implementation it can be seen from experimental result, to Escherichia coli, golden grape ball
Up to more than 95%, all medicine collaborations, have stronger bacteriostatic activity for bacterium, the inhibiting rate of Candida albicans.
Resisiting influenza virus of the present invention（FM1）Activity determination.
Antiviral Effect Activity determination is carried out using influenza virus A-prime mouse lung adapted strain (FM1), passes through influenza disease
Poison infection mdck cell, observation medicine act on pathological changes caused by virus, and calculating Antiviral Effect is efficient, measures neuraminic acid
Enzyme activity.The experimental results are shown inthe following table.
Ensureing the inhibiting rates of 5 groups of case study on implementation infected by influenza up to more than 80% it can be seen from experimental result, with
Virus control group compares, and 5 groups of case study on implementation samples can substantially reduce neuraminidase activity, and all medicine collaborations, have significant anti-
Virus effectiveness.
Comprehensive items result is it can be proved that hand cleanser of the present invention has good bactericidal effect, while has steady well
It is qualitative, it is prepared using pure natural sterilization component, there is reliable security, is adapted to long-time service.
Claims (2)
1. a kind of plants antimicrobial compound medicine, it is characterised in that be mainly made of the raw material of following parts by weight：
0.5 ~ 5 part of rhizoma Gastrodiae, 0.01 ~ 0.1 part of P-Cymene, 0.5 ~ 5 part of radix scutellariae, 0.1 ~ 1 part of frutus cnidii, 0.1 ~ 1 part of kuh-seng.
2. the preparation method of hand cleanser made of plants antimicrobial compound medicine according to claim 1, comprises the following steps：
Radix scutellariae, rhizoma Gastrodiae, frutus cnidii, kuh-seng are weighed in proportion, adds 10~50 parts of deionized waters, 2~5h of refluxing extraction, and repetition carries
Take once, merge extracting solution twice, add P-Cymene, N- acyl glutamic acids, vitamin E, aloe, glycerine, lanolin, SDS,
EDTA-2Na, sodium carboxymethylcellulose, sodium chloride, sodium citrate, citric acid, adjust pH to 5.0~7.0 after stirring and evenly mixing, quiet
Put, treat that foam is wholly absent, liquid is transparent to obtain the final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510534576.0A CN105078828B (en) | 2015-08-28 | 2015-08-28 | A kind of plants antimicrobial compound hand cleanser and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510534576.0A CN105078828B (en) | 2015-08-28 | 2015-08-28 | A kind of plants antimicrobial compound hand cleanser and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105078828A CN105078828A (en) | 2015-11-25 |
| CN105078828B true CN105078828B (en) | 2018-04-24 |
Family
ID=54560768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510534576.0A Active CN105078828B (en) | 2015-08-28 | 2015-08-28 | A kind of plants antimicrobial compound hand cleanser and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105078828B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109394584A (en) * | 2018-12-07 | 2019-03-01 | 安阳工学院 | A kind of preparation method of the biennial wormwood extract hand cleanser with antibacterial disinfection efficacy |
| CN113633600B (en) * | 2020-08-07 | 2024-02-13 | 湖南科技学院 | Alcohol-free washing-free disinfection hand sanitizer and preparation method thereof |
| CN114146033A (en) * | 2021-12-07 | 2022-03-08 | 安美科技股份有限公司 | Traditional Chinese medicine hand sanitizer and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100653A (en) * | 2009-12-22 | 2011-06-22 | 李慧娟 | Bath lotion containing extracts of chinese mugwort leaf and grass-leaved sweetflag rhizome |
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
| CN102949624A (en) * | 2012-11-06 | 2013-03-06 | 唐全荣 | Traditional Chinese herbal health care lotion and preparation method thereof |
| CN103767965A (en) * | 2014-01-04 | 2014-05-07 | 左权县桐峪镇嘉百岁农民专业合作社 | Forsythia suspensa leaf hand sanitizer and preparation method thereof |
-
2015
- 2015-08-28 CN CN201510534576.0A patent/CN105078828B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102100653A (en) * | 2009-12-22 | 2011-06-22 | 李慧娟 | Bath lotion containing extracts of chinese mugwort leaf and grass-leaved sweetflag rhizome |
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
| CN102949624A (en) * | 2012-11-06 | 2013-03-06 | 唐全荣 | Traditional Chinese herbal health care lotion and preparation method thereof |
| CN103767965A (en) * | 2014-01-04 | 2014-05-07 | 左权县桐峪镇嘉百岁农民专业合作社 | Forsythia suspensa leaf hand sanitizer and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105078828A (en) | 2015-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101185621B (en) | Chinese medicinal herb antimicrobial hand cleanser and preparation method thereof | |
| CN102755275B (en) | Dry cleaning and disinfecting gelatin prepared by using plant extracts | |
| CN104940122B (en) | A kind of leave Feminine care solution and preparation method thereof | |
| CN105078828B (en) | A kind of plants antimicrobial compound hand cleanser and preparation method thereof | |
| CN102423291A (en) | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof | |
| CN105087189B (en) | A kind of plants antimicrobial compound germicidal soap and preparation method thereof | |
| CN106309174A (en) | Folium isatidis hand cleanser and preparation method thereof | |
| CN104367529A (en) | Mosquito repellent floral water for purifying air and preparation method of mosquito repellent floral water | |
| CN107789278B (en) | Organic baby bath dew | |
| CN105754751A (en) | Anti-bacteria and water-saving detergent prepared from pure natural Chinese herbal medicines and plants and preparation method of detergent | |
| CN104666993B (en) | Plain skin surface antibacterial agent of a kind of bamboo jade-like stone and preparation method thereof | |
| CN109568217A (en) | A kind of preparation method of Salvia root P.E and its application in anti-acne | |
| CN103271859A (en) | Chinese herbal medicine toothpaste containing pseudo-ginseng saponin and honeysuckle extract | |
| CN108339017A (en) | Contain chitosan and grapefruit seed extract and uses composition as the antiviral of active constituent | |
| CN101711726A (en) | Ginseng skin-whitening liquid soap and preparation method thereof | |
| CN114306526B (en) | Compound broadleaf holly leaf traditional Chinese medicine extract and application thereof in preparing shower gel or hand sanitizer | |
| CN105434262A (en) | Largetrifoliolious-bugbane-rhizome toothpaste | |
| CN109077988A (en) | A kind of Goat Milk shower cream | |
| CN107115229A (en) | The active facial mask liquid of laminarin with anti-oxidation efficacy and preparation method | |
| CN101502537A (en) | Application of ginkgo episperm dry distillation liquid in preparing medicament for treating or preventing fungal disease | |
| CN113081911A (en) | Itching-relieving shower gel, preparation method thereof and shower bottle for containing itching-relieving shower gel | |
| CN103194341B (en) | Low-irritation baical skullcap root skin care soap | |
| CN103191159A (en) | Inflammation-diminishing bacterium-inhibition preparation and its preparation method and use | |
| CN102451152B (en) | Novel female care solution and its preparation method | |
| WO2020057285A1 (en) | Atractylodes oil and/or cassia twig oil, production method therefor and use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |