CN105056290A - Medical biological hydrogel functional dressing and preparing method thereof - Google Patents

Medical biological hydrogel functional dressing and preparing method thereof Download PDF

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CN105056290A
CN105056290A CN201510529568.7A CN201510529568A CN105056290A CN 105056290 A CN105056290 A CN 105056290A CN 201510529568 A CN201510529568 A CN 201510529568A CN 105056290 A CN105056290 A CN 105056290A
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powder
purified water
ceramide
coenzyme
laurocapram
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CN105056290B (en
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梁奕福
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DONGGUAN DAQING MEDICAL DEVICES Co.,Ltd.
GUANGXI DAQING BIOLOGICAL SCIENCE & TECHNOLOGY Co.,Ltd.
GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co.,Ltd.
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Guangxi Daqing Biotechnology Co Ltd
GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co Ltd
Dongguan Da Qing Medical Devices Co Ltd
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Abstract

The invention relates to the technical field of vaginitis treatment and nursing, in particular to a gynecological biological hydrogel functional dressing and a preparing method thereof. The dressing is composed of, by weight, 7.5-12% of chitosan quaternary ammonium salt, 0.21-0.36% of sodium alga acid, 12-18% of glycerinum, 0.22-0.35% of gelatin, 0.35-0.7% of magnesium ascorbyl phosphate, 0.008-0.012% of cell growth factor, 0.15-0.24% of ceramide, 0.45-0.75% of laurocapram, 0.35-0.65% of peppermint oil, and the balance purified water. The dressing can be used for treating gynecological inflammation such as vaginitis, can stop bleeding, relieve pain and repair wounds, and has the advantages of being capable of taking effect fast and free of side effects when used for treating gynecological inflammation.

Description

A kind of medical bio hydrogel functional dressings and preparation method thereof
Technical field
The present invention relates to medical bio technical field of hydrogel, particularly relate to a kind of medical bio hydrogel functional dressings and preparation method thereof.
Background technology
In present society, prostatosis has become a large public enemy of male, and the adjoint over the course for the treatment of urgent micturition of prostatosis, dysurea are very troubling, often makes work continuously, often can go to toilet; And midnight to get up increased frequency, to oneself, family brings many puzzlements per capita.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, provide a kind of medical bio hydrogel functional dressings, this dressing can be nursed prostate, reaches the effect of diuresis, alleviates or eliminate the effect of urgent micturition that prostatosis brings, frequent micturition.
For achieving the above object, the technical solution used in the present invention is:
A kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 8 ~ 13%
Polyhexamethylene guanidine 0.1 ~ 0.2%
Glycerol 13 ~ 17%
Coenzyme Q10 0.3 ~ 0.7%
Ceramide 0.1 ~ 0.4%
Laurocapram 0.4 ~ 0.7%
Oleum menthae 0.3 ~ 0.6%
Radix Codonopsis powder 0.1 ~ 0.3%
Astragalus membranaceus powder 0.1 ~ 0.3%
Radix Rehmanniae bloom 0.1 ~ 0.3%
Semen Plantaginis powder 0.2 ~ 0.5%
Purified water surplus.
Water instant cation chitosan quaternary ammonium salt has the performances such as good antibiotic property, film property, cation-adsorption, moisture absorbability and moisture retentivity, flocculability, antistatic behaviour.Its anti-microbial property is better than chitosan and other chitosan derivatives.After chitosan quaternary ammonium salt is water-soluble, ionize, containing a large amount of level Four ammonium cations in solution.Ammonium cation has certain fragmentation effect to antibacterial, fungus, virus.
Secondly polyhexamethylene guanidine, has broad-spectrum; Valid density is low; Speed of action is fast; Stable in properties; Premium properties soluble in water; Can use at normal temperatures; For a long time antibacterial, have no side effect; Polyhexamethylene guanidine is polyguanidine family macromolecule polymer, ionization can be produced in aqueous, its hydrophilic group part contains strong electropositive, absorption is usually in electronegative each bacterioid, virus, enter cell membrane, suppress the synthesis of film lactone plastid, cause thalline apoptosis, reach best bactericidal effect.
Chitosan quaternary ammonium salt, polyhexamethylene guanidine produce and form cation, can kill antibacterial, fungus and virus and isolate.
Glycerol, namely glycerol is without the sweet clear and bright thick liquid of color and taste, odorless; There is warm sweet taste.Glycerol can moisture content in draw air to skin moisture-keeping, also the moisture content in skin can be pinned, not allow it run off.There is effect of moisturizing.Moisturizing, moist effect can be played to the skin of baby.
Coenzyme Q10 coenzyme Q10 is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy, there is functions such as improving body immunity, enhancing antioxidation, slow down aging and enhancing human activity, medically be widely used in cardiovascular system diseases, extensively use it for nutrient and healthcare products and food additive both at home and abroad.Coenzyme Q10 (CoenzymeQ10), also known as ubiquinone (Ubiquinone, abbreviation UQ), is that one is present in natural fat-soluble quinones, and its structure and vitamin K, vitamin E are similar to plastoquinone.In human body cell, participate in energy manufacture and activation, be that prevention of arterial sclerosis forms the most effective antioxidation composition.Ubiquinone is present in most eukaryotic cell, especially mitochondrion.It is one of respiratory chain component; Its content on mitochondrial inner membrane is far away higher than the content of other components of respiratory chain, and the fat-soluble mobility making it have height on inner membrance, is particularly suitable as a kind of electron transit mediator of flowing.
Coenzyme Q10 mainly contains two effects in vivo, and one is be converted in the process of energy at nutrient substance to play an important role in mitochondrion, and two is have obvious lipoid peroxidization resistant.It is the power conversion agent in cell mitochondrial, and it produces ATP(adenosine triphosphate by shifting and transmit electronics participation " tricarboxylic acid cycle "), namely energy factors is for cellular metabolism.Coenzyme Q10 is effective antioxidant and free radical scavenger, it is embedded in mitochondrial inner membrane lipid bilayer as the ingredient of mitochondrial respiratory chain, alcohol of formula is become after 2 electronics that Mitochondria complex I or complex II accepts, then by electron transmission to complex III.Body coenzyme Q 10 is become alcohol of formula by a large amount of consumption, and it is effective antioxidant, and be also the electron carrier of motion, hydrogen atom is given to lipid peroxidation free radical from its hydroxyl by it simultaneously, thus reduces the lipid peroxide reaction of mitochondrial inner membrane.Generate the out-of-proportion free radical ubisemiquinone of alcohol of formula with coenzyme Q10 and coenzyme Q10 in the process, or to react formation superoxides with oxygen, free radical ubisemiquinone is transported free radical and is realized Detoxication under superoxide dismutase and catalatic effect, the respiratory chain that so moves in circles, by continuous for coenzyme Q10 regeneration alcohol of formula, has recovered its antioxidant activity effect.
Oleum menthae, skin that is unclean, that block can be nursed one's health, its refrigerant sensation, can blood capillary be shunk, releive itch, inflammation and burning, also can soft skin, also effect is had for removing blackhead and oiliness skin quality.
Oleum menthae has inhibitory action to herpes simplex virus, forest virus, mumps virus, has bacteriostasis to staphylococcus aureus, Staphylococcus albus, alpha streptococcus, group B streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax bacillus, diphtheria corynebacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli etc.; Water solublity Oleum menthae can excite nerve tip cold receptor and produce creeping chill, and reflexive cause the change of deep tissue blood vessel and play antiinflammatory, pain relieving, antipruritic effect.
Ceramide, also known as sphingolipid, is a kind of lipid being present in skin, plays an important role in epidermal keratinocytes layer formation process.When drying, desquamation, cracking phenomena appear in skin, when its barrier function obviously reduces, skin supplements ceramide can recover rapidly moisturizing and barrier function.
Cause xerosis cutis main cause to be that in horny layer of epidermis, ceramide content reduces, ceramide content height is directly related with skin dryness.Use ceramide can obviously strengthen adhesion strength between keratinocyte, improve skin dryness, reduce desquamation phenomenon.Ceramide has very strong associated water molecule ability, and it maintains moisture of skin by forming network structure in horny layer.Therefore, ceramide has the effect of maintenance moisture of skin.Use ceramide that ceramide content in horny layer of epidermis can be made to increase, xerosis cutis, desquamation, the situation such as coarse can be improved; Ceramide can increase epidermal keratinocytes layer thickness simultaneously, improves skin moisture holding capacity, reduces wrinkle, strengthens skin elasticity, delay skin aging.
Ceramide is a kind of water-soluble grease metallic substance, and it is close with the structure of matter forming keratodermatitis, can penetrate into skin very soon, and the water in horny layer combines, and forms a kind of network structure, pins moisture.
Laurocapram is nonpolar transdermal enhancer, and it can make cutin softening, strengthens permeability, makes drugs through skin barrier, improves local or systemic blood levels, improves preparation bioavailability.All Penetration enhance is had to lipotropy hydrophilic medicament.Be a kind of new and effective penetrating agent, due to use safety, efficient, nontoxic, consumption is few and all have hydrophilic and hydrophobic compound and shortly ooze the advantages such as effect, is one of current classic drug transdermal promoter.
Radix Codonopsis (formal name used at school; Codonopsispilosula) sheet of ovalize or similar round, surperficial yellowish-brown or lark, tangent plane yellow-white or yellowish-brown, have crack or Flos Chrysanthemi stricture of vagina, there are the faint yellow center of circle in central authorities.Periphery yellowish white puts yellowish-brown, has vertical wrinkle.Have special aroma, taste is micro-sweet.Raw Radix Codonopsis sheet supplementing QI for promoting the production of body fluid power victory.Be usually used in gas Tianjin two to hinder or deficiency of both QI and blood.Radix Codonopsis sweet in the mouth, property is put down.Have invigorating the spleen and replenishing QI, quench the thirst, spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.[1] lazy speech lose heart, myasthenia of limbs, be off one's feed, the deficiency of vital energy, gas Tianjin two are empty, QI and blood is two loses and the disease such as blood deficiency and yellow complexion.But exterior syndrome is not separated and can not the using of the fullness in the epigastrium and abdomen domination of pathogen.This product effect is similar to Radix Ginseng, and only the efficacy of a drug is weak.Control general deficiency syndrome, Radix Ginseng can be replaced to use; Collapse is heavily demonstrate,proved, then be still advisable with Radix Ginseng.Autumn excavates, and cleans, dries.
Radix Codonopsis is conventional qi-invigorating herb, and its property is flat, sweet in the mouth, enters spleen, lung meridian, tool invigorating the spleen and replenishing QI, stomach function regulating such as to be nourished blood at the effect, should be used for fatigue and weakness usually, lassitude, consciously to breathe hard, the slightly movable deficiency of vital energy patient with regard to dyspnea with rapid and short breath, because QI invigorating also contributes to hemopoietic, so Radix Codonopsis is also applicable to QI and blood deficiency pale complexion, feel dizzy, have no appetite, defecate rare soft, easy to catch cold patient.
The Radix Astragali: function with cure mainly invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.The invigorating middle warmer of processed with honey Radix Astragali QI invigorating.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.Modern medicine study shows, the Radix Astragali includes and multiple antibiotic effective ingredient, and the immunologic function of energy enhancing body, therefore can also be used for the generation preventing some infectious disease.No matter from Chinese traditional treatment, or modern medicine is observed, and the Radix Astragali is all good medicines simply.So, the custom from ancient times just having " winter gets the food that the Radix Astragali is made into nourishing and fit keeping function " among the people.
Radix Codonopsis, the Radix Astragali are mainly used in QI invigorating and antibacterial.
Radix Rehmanniae clearing away heat and promoting production of body fluid, after cool, hemostasis; For hot blast impairment of YIN, crimson tongue excessive thirst, send out speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid; For calentura excessive thirst, send out speckle dermexanthesis, yin asthenia generating intrinsic heat, haematemesis, epistaxis, diabetes, infectious hepatitis.This product sweet-bitter flavor, cold in nature and enter blood system, can the heat of clearing heat in YING system blood system and removing heat from blood.Height for epidemic febrile disease is warm, thirsty, deep red tongue, and prescription is as qingying decoction.In addition, these product still have effect of hemostasis by removing heat from blood, can be used for the various hemorrhages of heat in blood.
Radix Rehmanniae clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, is the refrigerant product moistened, is good at nourishing YIN and clearing away heat removing heat from blood.Effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.Be mainly used in pestilence heat to join the army mass formed by blood stasis; All hemorrhages such as bleeding due to blood-heat haematemesis, epistaxis, hematuria, metrostaxis; Also control calentura later stage impairment of YIN, fever due to yin deficiency, the yin deficiency that interior-heat is quenched one's thirst; The effect of supplementing fluid to relax the bowels can be caused for the hot-tempered constipation of deficiency of YIN intestinal.
Semen Plantaginis is in zoopery, Semen Plantaginis has diuresis, and Semen Plantaginis can make the discharge of moisture, sodium chloride, carbamide and uric acid increase and have diuresis, in addition, Semen Plantaginis has impels rabbit membrana synovialis capsulae articularis connective tissue proliferation effect, thus makes the joint capsule relaxed recover original tensity.Also have report to think, Semen Plantaginis alcoholic extract has intends choline effect, can reduce the blood pressure of anesthetized dog, cat, suppress extrasomatic rabbit heart, the frog heart, the intestinal tube of excited rabbit, rat and Cavia porcellus, and can be suppressed by atropine, and in addition, Semen Plantaginis is still eliminated the phlegm and antitussive effect.But Semen Plantaginis decoct has not showed diuresis to normal person, rabbit, rat.
Semen Plantaginis nature and flavor are sweet, are slightly cold, and as Chinese medicine, it cures mainly function is clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily." book on Chinese herbal medicine newly organized ": Semen Plantaginis, sweet in the mouth, salty, feeble QI is trembled with fear, nontoxic.Enter bladder, spleen, kidney three warp.Merit patent water, logical urinary catheter is the most refreshing, only drenches drop and has loose bowels, can close orifice for discharging seminal fluid, heat of dispeling the wind, and the kind Akamu that disappears, expedites the emergence of meritorious.But property is sliding, and diuretic can be multiplex, also not flat with it.Rush down and be suitable for few use, with its too sliding profit also.
In dressing composition: chitosan quaternary ammonium salt, polyhexamethylene guanidine mainly play a part sterilization, antibacterial; Ceramide has antianaphylactic effect and improves skin environment simultaneously, prevents skinfold; Laurocapram all has obvious transdermal to help the effect of oozing to hydrophilic and lipophilic drugs, and auxiliary other drug composition skin permeation, repairs prostate; Coenzyme Q10 plays antioxidative effect, can provide energy simultaneously, help it to repair to prostatic cell; Glycerol is mainly used in the moisturizing of prostate appearance skin, lubrication and gel regulator; Oleum menthae mainly plays the cleaning to skin, plays pain relieving, antipruritic effect simultaneously; Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder play antibacterial bacteriostatic treatment prostatitis, chronic prostate hyperplasia, hypertrophy cause abscess, urgent micturition, frequent micturition, dysurea.
Preferably, a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Purified water surplus.
Again preferably, a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanidine 0.2%
Glycerol 15%
Coenzyme Q10 0.5%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.2%
Radix Rehmanniae bloom 0.2%
Semen Plantaginis powder 0.3%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Preferably, a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Pollen Typhae 0.15 ~ 0.2%
Purified water surplus.
Pollen Typhae cures mainly: trusted subordinate's frigiopyrexia of bladder, diuresis, hemostasis, repercussive blood.Clothes of a specified duration are made light of one's life by commiting suicide physical strength profiting, the angle that prolongs life (" herbal classic ").Control dysentery blood, epistaxis is spitted blood, and hematuria rushes down blood, dredging water passages, qualcomm meridian, only man's metrorrhagia (Zhen Quan).Married woman's leukorrhagia, the moon waits irregular, vim and vigour cardiac and abdominal pain, and pregnant woman's hematochezia is had an abortion, and blood fortune mass formed by blood stasis, youngster rests the head on shoot, and it is vexed that blood is flutterred on top, evacuation of pus, furuncle urticaria toxic swelling, lower milk, stopping leak essence (bright greatly).Removing heat from blood and promoting blood circulation, the only all pains of trusted subordinate (time precious).The effects such as Pollen Typhae has hemostasis, blood stasis dispelling, treating stranguria.
Before the treatment in row gland process, Pollen Typhae can play diuresis, the effect of hemostasis; Alleviate urgent micturition, dysurea.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Again preferably, a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Pollen Typhae 0.15 ~ 0.2%
Hydrogen peroxide 1 ~ 2%
Purified water surplus.
Hydrogen peroxide has good oxidation effectiveness, when adopting the wound of the hydrogen peroxide of low concentration (especially weight ratio is lower than 3%) and skin, pus or dirt to meet, decomposes immediately and generates oxygen.This oxygen atom being not yet combined into oxygen molecule, has very strong oxidability, when contacting with antibacterial, can destroy microorganism, kill antibacterial.Can provide an aerobic environment, the collagen protein killing anaerobe and aid in skin is formed simultaneously.Here the content of hydrogen peroxide refers to: the weight content of pure hydrogen peroxide in whole dressing: 1% ~ 2%.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Because content 100% hydrogen peroxide is difficult to obtain, the hydrogen peroxide of the quality such as the hydrogen peroxide employing in step one, other concentration hydrogen peroxide substitute; I.e. step one, join get hydrogen peroxide time, other concentration hydrogen peroxide getting equivalent can being joined, getting 30% hydrogen peroxide (quality containing hydrogen peroxide is equal) of equal size hydrogen peroxide as joined; Step 2 replaces with: the purified water taking surplus.
Beneficial effect of the present invention is:
Can protect prostate in early stage, improve its antibacterial, immunocompetence; Invigorating the spleen and replenishing QI, prevention prostatitis; In the treatment phase, can auxiliary treatment prostate, there is diuresis effect, abscess, urgent micturition, dysurea etc. that treatment prostatosis causes simultaneously.
Detailed description of the invention
Below the present invention is described further.
Embodiment 1: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 8%
Polyhexamethylene guanidine 0.2%
Glycerol 13%
Coenzyme Q10 0.7%
Ceramide 0.4%
Laurocapram 0.4%
Oleum menthae 0.6%
Radix Codonopsis powder 0.1%
Astragalus membranaceus powder 0.3%
Radix Rehmanniae bloom 0.1%
Semen Plantaginis powder 0.5%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 1: Huang, man, 21 years old, slight prostatitis, indistinctly had dysurea; The medical bio hydrogel functional dressings of coating the present embodiment one week, every day 3 times; Urine is normal, without pain, and NIP.
Embodiment 2: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 13%
Polyhexamethylene guanidine 0.1%
Glycerol 17%
Coenzyme Q10 0.3%
Ceramide 0.1%
Laurocapram 0.7%
Oleum menthae 0.3%
Radix Codonopsis powder 0.3%
Astragalus membranaceus powder 0.1%
Radix Rehmanniae bloom 0.3%
Semen Plantaginis powder 0.2%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 2, Zhang, man, 70 years old, suffers from chronic prostate hyperplasia, frequent frequent micturition, urgent micturition; Use medical bio hydrogel functional dressings every day 3 times of the present embodiment; After one week, frequent micturition, urgent micturition slow down, after one month, and happy, the normal urine of urinary tract.
Embodiment 3: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanidine 0.18%
Glycerol 14%
Coenzyme Q10 0.4%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.15%
Astragalus membranaceus powder 0.2%
Radix Rehmanniae bloom 0.15%
Semen Plantaginis powder 0.25%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 3: Lin, man, 61 years old, suffers from prostate hyperplasia, frequent dysurea, urgent micturition.Use medical bio hydrogel functional dressings every day 3 times of the present embodiment, after 3 days, dysurea starts to slow down, and each urine volume increases, and after 2 weeks, dysurea disappears, without urgent micturition.
Embodiment 4: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanidine 0.2%
Glycerol 16%
Coenzyme Q10 0.6%
Ceramide 0.3%
Laurocapram 0.5%
Oleum menthae 0.4%
Radix Codonopsis powder 0.18%
Astragalus membranaceus powder 0.25%
Radix Rehmanniae bloom 0.25%
Semen Plantaginis powder 0.4%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 4: Lee, man, 35 years old, suffers from prostatitis; Frequent urgent micturition, frequent micturition; Have a strong impact on life and work, use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after one week, urgent micturition, frequent micturition slow down; After 3 weeks, urine frequency retrieval is normal.
Embodiment 5: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanidine 0.2%
Glycerol 15%
Coenzyme Q10 0.5%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.2%
Radix Rehmanniae bloom 0.2%
Semen Plantaginis powder 0.3%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 5: Zhang, man, 45 years old, suffers from prostatosis, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after one week, urgent micturition, frequent micturition slow down and without pain; After 2 weeks, urine frequency retrieval is normal.
Embodiment 6: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanidine 0.2%
Glycerol 16%
Coenzyme Q10 0.4%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.15%
Radix Rehmanniae bloom 0.25%
Semen Plantaginis powder 0.4%
Pollen Typhae 0.15%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 6: Lin, man, 52 years old, suffers from prostatic hyperplasia, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 3 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After one week, urine frequency retrieval is normal and without pain.
Embodiment 7: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanidine 0.18%
Glycerol 14%
Coenzyme Q10 0.6%
Ceramide 0.3%
Laurocapram 0.5%
Oleum menthae 0.4%
Radix Codonopsis powder 0.15%
Astragalus membranaceus powder 0.25%
Radix Rehmanniae bloom 0.25%
Semen Plantaginis powder 0.25%
Pollen Typhae 0.2%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 7 field, man, 35 years old, suffers from prostatitis, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 5 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After one week, urine frequency retrieval is normal and without pain.
Embodiment 8: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanidine 0.19%
Glycerol 15%
Coenzyme Q10 0.5%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.2%
Radix Rehmanniae bloom 0.2%
Semen Plantaginis powder 0.3%
Pollen Typhae 0.2%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 8: Lee, man, suffers from prostatic hyperplasia in 65 years old, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 5 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After one week, urine frequency retrieval is normal and without pain.
Embodiment 9: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9%
Polyhexamethylene guanidine 0.18%
Glycerol 14%
Coenzyme Q10 0.4%
Ceramide 0.3%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.15%
Radix Rehmanniae bloom 0.15%
Semen Plantaginis powder 0.25%
Pollen Typhae 0.15%
Hydrogen peroxide 1%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 9: field, man, 48 years old, suffers from prostatitis, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 8 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After two weeks, urine frequency retrieval is normal and without pain.
Embodiment 10: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 11%
Polyhexamethylene guanidine 0.2%
Glycerol 16%
Coenzyme Q10 0.6%
Ceramide 0.2%
Laurocapram 0.5%
Oleum menthae 0.4%
Radix Codonopsis powder 0.15%
Astragalus membranaceus powder 0.25%
Radix Rehmanniae bloom 0.25%
Semen Plantaginis powder 0.4%
Pollen Typhae 0.2%
Hydrogen peroxide 2%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 10: close certain, man, 23 years old, suffers from prostatitis, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 3 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After one week, urine frequency retrieval is normal and without pain.
Embodiment 11: a kind of medical bio hydrogel functional dressings, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Pollen Typhae 0.15 ~ 0.2%
Hydrogen peroxide 1.5%
Purified water surplus.
A preparation method for above-mentioned medical bio hydrogel functional dressings, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 11: Zhao, man, 27 years old, suffers from prostatitis, is often attended by urgent micturition, frequent micturition phenomenon, and has pain; Use the medical bio hydrogel functional dressings of the present embodiment, every day 3 times, after 5 days, urgent micturition, frequent micturition slow down and keenly feel and alleviate; After one week, urine frequency retrieval is normal and without pain.
Clinical trial: prostatosis 120 patients that suffer from for Dongguan andrology of hospital follow the tracks of, and these 120 patient ages, between 20 ~ 70 years old, are all attended by the symptoms such as urgent micturition; Random use the medical bio hydrogel functional dressings of above-described embodiment after, wherein 50 just had and slow down sign in one week, had 115 patients can normal urine in 3 weeks, and treatment rate reaches more than 95%.
Below be only the preferred embodiment of the application, equivalent technical solutions on this basis still falls into application protection domain.

Claims (8)

1. a medical bio hydrogel functional dressings, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 8 ~ 13%
Polyhexamethylene guanidine 0.1 ~ 0.2%
Glycerol 13 ~ 17%
Coenzyme Q10 0.3 ~ 0.7%
Ceramide 0.1 ~ 0.4%
Laurocapram 0.4 ~ 0.7%
Oleum menthae 0.3 ~ 0.6%
Radix Codonopsis powder 0.1 ~ 0.3%
Astragalus membranaceus powder 0.1 ~ 0.3%
Radix Rehmanniae bloom 0.1 ~ 0.3%
Semen Plantaginis powder 0.2 ~ 0.5%
Purified water surplus.
2. a kind of medical bio hydrogel functional dressings according to claim 1, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Purified water surplus.
3. a kind of medical bio hydrogel functional dressings according to claim 1, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 10%
Polyhexamethylene guanidine 0.2%
Glycerol 15%
Coenzyme Q10 0.5%
Ceramide 0.2%
Laurocapram 0.6%
Oleum menthae 0.5%
Radix Codonopsis powder 0.2%
Astragalus membranaceus powder 0.2%
Radix Rehmanniae bloom 0.2%
Semen Plantaginis powder 0.3%
Purified water surplus.
4. a medical bio hydrogel functional dressings, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Pollen Typhae 0.15 ~ 0.2%
Purified water surplus.
5. a medical bio hydrogel functional dressings, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 9 ~ 11%
Polyhexamethylene guanidine 0.18 ~ 0.2%
Glycerol 14 ~ 16%
Coenzyme Q10 0.4 ~ 0.6%
Ceramide 0.2 ~ 0.3%
Laurocapram 0.5 ~ 0.6%
Oleum menthae 0.4 ~ 0.5%
Radix Codonopsis powder 0.15 ~ 0.2%
Astragalus membranaceus powder 0.15 ~ 0.25%
Radix Rehmanniae bloom 0.15 ~ 0.25%
Semen Plantaginis powder 0.25 ~ 0.4%
Pollen Typhae 0.15 ~ 0.2%
Hydrogen peroxide 1 ~ 2%
Purified water surplus.
6. a preparation method for the arbitrary described medical bio hydrogel functional dressings of claims 1 to 3, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
7. a preparation method for medical bio hydrogel functional dressings according to claim 4, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
8. a preparation method for medical bio hydrogel functional dressings according to claim 5, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, glycerol, coenzyme Q10, ceramide, laurocapram, Oleum menthae, Radix Codonopsis powder, astragalus membranaceus powder, Radix Rehmanniae bloom, Semen Plantaginis powder, Pollen Typhae, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
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Address after: 523000, Guangdong City, Dongguan province Sanyuanli community finance business building, two floor, No. 205-208, Dongguan City Da Qing Medical Equipment Co., Ltd.

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