CN105055748B - Pain bone-knitting plaster and decocting method thereof - Google Patents

Abstract

The invention discloses a pain bone-knitting plaster and a decocting method thereof. The pain bone-knitting plaster is mainly prepared from the following raw materials, by weight, 15-25 g of saffron, 25-35 g of dragon's blood, 20-30 g of pangolin, 40-60 g of pseudo-ginseng, 30-45 g of monkshood, 30-45 g of kusnezoff monkshood root, 35-50 g of elderberry, 40-55 g of clematis root, 40-50 g of cortex acanthopanacis, 40-50 g of drynaria rhizome, 30-45 g of homalomena occulta, 40-50 g of cassia twig, 30-45 g of native copper, 40-55 g of lesser spider, 40-55 g of arisaema tuber and 45-65 g of diverse wormwood herb. The plaster is used for external application, is convenient to use and takes effect quickly; can be used for treating prolapse of lumbar intervertebral disc, hyperosteogeny of neck, shoulder, waist and knee, ankylosing spondylitis, and lumbar spondylolisthesis. Through statistics of treatment and application of 360 patients, the cure rate reaches 88.6%, the total effective rate is 97.7%, the curative effect is reliable, and the effect is obvious.

Description

Pain bone-knitting plaster and decocting method thereof

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a pain bone-knitting plaster and a decocting method thereof.

Background

The bone disease is "osteopathy" from the professional perspective, which is one of three major pathologies of orthopedic diseases, and the other two are "orthopedics" and "tendon injury" respectively. Bone diseases are also the most common diseases in orthopedic diseases, and are mainly divided into: congenital bone disease, metabolic bone disease, osteonecrosis, occupational bone disease, endemic bone disease, joint degenerative bone disease, bone tumor, bone carbuncle and cellulitis, bone tuberculosis, osteoarticular arthralgia, fistula syndrome, tendon spasm, etc.

Bone diseases generally include: rheumatic arthritis, rheumatoid arthritis, degenerative arthritis, ankylosing spondylitis, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, femoral head necrosis, puerperal rheumatism, etc.

Rheumatoid arthritis is a common acute or chronic inflammation of the connective tissue. Can repeatedly attack and involve the heart; clinically, it is characterized by migratory weakness, severe symptoms and pain of joints and muscles, and belongs to allergic diseases, and it is one of the main manifestations of rheumatic fever, and is mostly caused by acute fever and joint pain.

Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by arthromeningitis; synovitis persists with repeated attacks, which can lead to cartilage and bone destruction in joints, joint dysfunction, and even disability. Vasculitis affects all organs of the body, so it is also called rheumatoid disease.

Degenerative arthritis, also known as hypertrophic arthritis, refers to the common symptoms of lumbago, leg pain, and arthralgia in some elderly people. It is also called senile arthritis because it is often found in the elderly. Senile degeneration is the main cause of degenerative arthritis. After the middle-aged and the elderly, all tissues and organs can generate degenerative changes; bone and joint tissues are no exception, degenerative changes occur particularly well in weight bearing joints and multi-mobile joints. Excessive weight bearing or excessive use of certain joints may promote degenerative changes. In addition, factors such as intra-articular fractures, diabetes, prolonged inappropriate use of adrenocortical hormones, etc., can promote the formation of degenerative changes and accelerate the development of existing degenerative changes.

Ankylosing spondylitis belongs to the category of rheumatism, and is one of seronegative spondyloarthropathies. The cause of the disease is not clear, and the chronic disease with the spine as the main pathological change affects the sacroiliac joints, causes the spinal rigidity and fibrosis, causes the pathological changes of eyes, lungs, muscles and bones with different degrees, and belongs to the autoimmune disease.

Cervical spondylosis is also known as cervical syndrome, is a general name of cervical osteoarthritis, proliferative cervical spondylitis, cervical radicular syndrome and cervical disc herniation, and is a disease based on degenerative pathological changes. Mainly, due to long-term strain of cervical vertebrae, hyperosteogeny, or prolapse of intervertebral disc and ligament thickening, the spinal cord, nerve root or vertebral artery of cervical vertebrae are pressed, resulting in a series of clinical syndromes of dysfunction. It is manifested as degeneration of cervical intervertebral disc and a series of secondary pathological changes, such as instability and loosening of vertebral segment; herniation or herniation of the nucleus pulposus; forming bone spurs; ligament hypertrophy, secondary spinal stenosis, and the like irritate or compress adjacent tissues such as nerve roots, spinal cord, vertebral artery, and cervical sympathetic nerves, and cause syndromes of various symptoms and signs.

The lumbar spondylosis in medicine comprises the diseases of lumbar disc herniation, lumbar hyperosteogeny, lumbar muscle strain, lumbar sprain, lumbar degenerative disease, rheumatism or rheumatoid lumbago, lumbar tuberculosis, lumbago due to wind-cold-dampness, lumbago due to blood stasis, lumbago due to damp-heat, lumbago due to kidney deficiency, cervical spondylosis and the like.

Scapulohumeral periarthritis is a common disease with pain in shoulder joints and difficulty in movement as main symptoms. The age of good onset of this disease is about 50 years old, while the incidence of female disease is slightly higher than that of male disease, which is often seen in physical workers. If no effective treatment is available, the functional activity of the shoulder joint may be seriously affected. According to clinical observation, hospitals often use the medicine combination tangzhong for treatment, the shoulder joint of the disease is paroxysmal pain in early stage, is usually induced by weather change and fatigue, gradually develops persistent pain later and gradually aggravates, is light in day and heavy in night, and has limited active and passive activities in all directions. When the shoulder is pulled, severe pain may be caused. The shoulder joints may have extensive tenderness and radiate towards the neck and elbows, and there may also be different degrees of atrophy of the deltoid muscles.

The hyperosteogeny is also called as proliferative osteoarthritis, degenerative joint disease, senile arthritis and hypertrophic arthritis, and is a disease with the symptoms of secondary hyperosteogeny, joint deformation, joint pain, limited movement and the like when abnormal load is applied. Hyperosteogeny is divided into primary and secondary.

Femoral head necrosis, also known as avascular necrosis of the femoral head, is one of the common osteoarthropathies. Most of them are caused by rheumatism, hematopathy, caisson's disease, burn, etc., which first destroy the blood supply of the adjacent articular tissues and then cause necrosis. The main symptoms of the traditional Chinese medicine gradually progress from intermittent pain to persistent pain, muscle spasm is caused by the pain, joint movement is limited, and severe disabling and lameness are caused finally. Hormonal drugs can also cause the disease. The Chinese medicine considers that the causes of the disease are external and internal, and the interaction of the external and internal causes can unbalance yin and yang of the human body and cause diseases due to the imbalance of qi and blood, which are also called as "bi-arthralgia of legs", "bi-arthralgia of bone" and "bone atrophy".

At present, there are many reports on patent documents for treating orthopedic diseases. For example: 1. the invention has application number of 201510026701.7 and is named as 'plaster for activating meridians and removing blood stasis and promoting bone growth and a preparation method thereof'. 2. The invention has application number of 200610046888.8, and is named as 'plaster for treating bone diseases and a preparation method thereof'. 3. Application No. 201010134579.2 entitled "plaster for treating bone diseases".

Disclosure of Invention

The technical problem to be solved by the invention is as follows: provides a pain bone-knitting plaster and a decocting method thereof. The pain bone-knitting plaster of the invention is mainly used for treating the symptoms of lumbar disc herniation, hyperplasia of neck, shoulder, waist and knee, ankylosing spondylitis and lumbar spondylolisthesis hyperplasia. The pain bone-knitting plaster is used for treating the four orthopedic diseases, has no toxic or side effect in the treatment process, and has obvious treatment effect.

In order to solve the problems, the invention adopts the technical scheme that:

the invention provides a pain bone-knitting plaster which is prepared from, by weight, 15-25 g of saffron, 25-35 g of dragon's blood, 20-30 g of pangolin, 40-60 g of pseudo-ginseng, 30-45 g of monkshood, 30-45 g of kusnezoff monkshood root, 35-50 g of elderberry, 40-55 g of clematis root, 40-50 g of acanthopanax bark, 40-50 g of drynaria rhizome, 30-45 g of homalomena rhizome, 40-50 g of cassia twig, 30-45 g of native copper, 40-55 g of small argy bone, 40-55 g of arisaema consanguineum and 45-65 g of diverse wormwood herb.

According to the pain bone-knitting plaster, the pain bone-knitting plaster is mainly prepared from 18-22 g of saffron, 28-32 g of dragon's blood, 22-26 g of pangolin scales, 45-55 g of pseudo-ginseng, 35-42 g of monkshood, 35-42 g of kusnezoff monkshood root, 38-45 g of elderberry, 45-50 g of clematis root, 45-48 g of cortex acanthopanacis, 42-46 g of rhizoma drynariae, 35-40 g of homalomena occulta, 45-48 g of cassia twig, 36-45 g of native copper, 45-52 g of lesser spider, 45-50 g of rhizoma arisaematis and 50-60 g of artemisia.

According to the pain bone-knitting plaster, the radix aconiti is prepared radix aconiti, and the radix aconiti kusnezoffii is prepared radix aconiti kusnezoffii.

In addition, a decocting method of the pain bone-knitting plaster is provided, and the decocting method comprises the following steps:

a. firstly, weighing various raw material medicines according to the raw material composition proportion of the pain bone-knitting plaster for later use;

b. uniformly mixing the raw materials weighed in the step a, pouring the mixture into 2000-3000 g of sesame oil, heating, boiling, decocting at 40-60 ℃ for 40-80 minutes while continuously stirring, and filtering out dregs to obtain cream oil;

c. b, heating the paste oil obtained in the step b to boiling, slowly adding red lead, wherein the mass ratio of the plaster to the red lead is 2:1, after the red lead is added, decocting for 1-1.5 hours at the temperature of 40-60 ℃, continuously stirring in the decocting process, and decocting to obtain the plaster;

d. and d, pouring the plaster obtained in the step c into water, soaking for 20-24 hours, taking out after soaking, and spreading on cloth to obtain the pain bone-knitting plaster.

The pharmacological actions of various raw materials of the invention are as follows:

saffron: also called as saffron, it is neutral in nature and sweet in flavor; enter heart and liver meridians. The efficacy is mainly as follows: 1. promoting blood circulation by removing blood stasis: the medicine has red color, enters heart and liver channels, is sweet and cold in taste, and has the functions of enriching blood and activating blood, removing blood stasis and softening liver, and cooling blood and removing toxicity. It is commonly used for amenorrhea, postpartum abdominal pain due to blood stasis, traumatic injury, typhoid fever, mania, etc. 2. Resolving stagnation and resolving stagnation: saffron has sweet and sweet taste, enters liver and heart meridians, and is good at activating blood circulation to dissipate blood stasis, soothing liver and relieving depression, regulating qi and relieving pain. It is commonly used for hypochondriac distention and fullness, absentmindedness, chest distress and oppression.

Dragon's blood: this herb is sweet, salty and neutral in flavor; and (5) small toxicity. It enters heart and liver meridians. The efficacy is mainly as follows: the product has effects in dispelling blood stasis, relieving pain, stopping bleeding, promoting granulation, and healing wound; mainly treats traumatic injury, internal injury blood stasis and pain, dysmenorrheal, postpartum blood stasis and abdominal pain, traumatic hemorrhage, scrofula, ecthyma for a long time, hemorrhoids and other symptoms.

Pangolin scales: slightly cold in nature and salty in taste, entering liver and stomach meridians. The efficacy is mainly as follows: 1. dredging collaterals and dispelling wind: the product has good properties of moving, dredging collaterals, dispelling pathogenic wind, eliminating dampness, and eliminating arthralgia, stiffness and deformation. 2. Carbuncle eliminating and pus discharging: it can move qi and activate blood, relieve dysmenorrhea and dissipate blood stasis, and induce heat-clearing herbs to directly reach the affected part, if pus is not formed, then disperse and burst. It is most suitable for abscess with pus forming into immature apparatus. 3. Activating collaterals and clearing channels: it can break qi and move blood, and also can move and disperse, so qi can disperse blood stasis and menstruation can go downward. 4. Dredge collaterals and promote lactation. 5. Eliminating mass and removing accumulation: being salty and cold, it can soften hardness and dissipate nodulation, unblock collaterals and activate blood, so it is specially designed to move and disperse, so it can direct the guiding herbs to the affected part, so it is indicated for mass-eliminating, accumulation-resolving and nodulation-dissipating.

Pseudo-ginseng: warm in nature, sweet and slightly bitter in taste, and non-toxic; enter the liver, stomach and large intestine meridians. The efficacy is mainly as follows: 1. hemostasis and stasis dissipation: it is good at stopping bleeding and dissipating blood stasis, and is commonly indicated for blood syndromes such as metrorrhagia and metrostaxis, postpartum anemic fainting, persistent lochia, traumatic hemorrhage, etc. 2. Promoting blood circulation and relieving swelling: being bitter in flavor and warm in nature, bitter in flavor, purging and unblocking in warm, entering blood system to activate blood and resolve stasis, resolve swelling and alleviate distention, it is indicated for traumatic injuries and innominate carbuncle and swelling. 3. Stasis dissipating and pain relieving: it has the best action of activating blood and resolving stasis, and relieving swelling and pain, so it is indicated for pain due to blood stasis, pain due to injury, swelling and pain due to carbuncle.

Radix aconiti preparata: this herb is pungent, bitter and toxic in flavor; they enter heart, liver, kidney and spleen meridians. The efficacy is mainly as follows: the product has effects of dispelling pathogenic wind, removing dampness, warming channels, and relieving pain; it is commonly used for wind-cold-dampness arthralgia, breast pain, chest distending pain, joint pain, cold pain of heart and abdomen, cold hernia pain, anesthesia and pain relief.

Preparing kusnezoff monkshood root: this herb is pungent, bitter and hot in flavor; they enter heart, liver, kidney and spleen meridians. The efficacy is mainly as follows:

the product has effects of dispelling pathogenic wind, removing dampness, warming channels, and relieving pain; it is commonly indicated for arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, and hernia of cold type to alleviate pain.

Elderberry: the product is sweet and bitter in taste, mild in nature and non-toxic; it enters liver meridian. The efficacy is mainly as follows: the product has effects in expelling pathogenic wind, removing dampness, promoting blood circulation, relieving pain, stopping bleeding, clearing away heat and toxic materials, dredging channels, and promoting reunion of fractured bones; it is commonly used to treat arthralgia due to dampness, gout, various inflammatory diseases, rheumatic arthralgia, lumbago, leg pain, fracture, tumor, Kaschin-Beck disease, acute and chronic nephritis, rubella, traumatic injury, swelling and pain due to fracture, traumatic hemorrhage, etc.

Clematis root: it is pungent, salty, warm in nature and toxic; enter bladder meridian. The efficacy is mainly as follows: the product has effects of dispelling pathogenic wind, removing dampness, dredging collaterals, relieving pain, eliminating phlegm, and removing stagnation; it is commonly used to treat stubborn arthralgia due to wind-cold, rheumatic arthralgia, numbness of limbs, cold pain of waist and knees, spasm of tendons and vessels, difficulty in flexion and extension, tinea pedis, malaria, abdominal mass accumulation, tetanus, tonsillitis, and bone sticking throat.

Cortex acanthopanacis: it is a wind-dispelling and blood-activating herb; has the effects of expelling wind-damp, strengthening bones and muscles, promoting blood circulation, removing blood stasis and the like; it is commonly indicated for arthralgia due to cold-dampness, spasm and urgency of muscles and bones, lumbago, yang fistula, weak foot, edema, beriberi, deep-rooted carbuncle, swelling and pain, traumatic injuries and overstrain.

Rhizoma drynariae: this herb is bitter in taste and warm in nature; it enters kidney and liver meridians. The efficacy is mainly as follows: the product has effects in invigorating kidney, strengthening bone, promoting wound healing, and relieving pain; it is commonly indicated for lumbago due to kidney deficiency, tinnitus, deafness, tooth loosening, traumatic injury, sprain, contusion, and fracture of tendons and bones.

The thousand years of the year see: being bitter and pungent in flavor and warm in nature, it enters liver and kidney meridians. The efficacy is mainly as follows: the product has effects in expelling pathogenic wind and dampness, relaxing muscles and tendons, activating collateral flow, relieving pain, and relieving swelling; it is commonly indicated for arthralgia due to wind-damp, soreness and weakness of limbs and joints, bone and muscle fistulization, traumatic injuries, stomachache, abscess, ulcer and swelling.

Cassia twig: warm in nature, pungent and sweet in flavor; enter bladder, heart and lung meridians. The efficacy is mainly as follows: 1. relieving muscles and sweating: it is a common herb for exterior syndrome of wind-cold syndrome because it has actions of ascending and floating, moving upwards and outwards, penetrating nutrient and defensive qi, expelling wind and cold, expelling wind and inducing sweat. It is commonly indicated for exterior deficiency due to wind-cold, exterior syndrome due to depression of the sun, exterior cold and interior heat. 2. Warming and dredging blood vessels: it is pungent and warm, warming yang qi of the whole body, and unblocking blood vessels of the whole body. It is the essential herb for warming and dredging blood vessels because it warms viscera internally and dispels exterior cold. It is commonly used for blood deficiency, cold, uterus stagnation and blood impediment. 3. Warming yang and regulating qi: it is pungent and warm in property, able to stimulate yang qi, open striae and regulate water passage, and help yang of triple energizer, and is the essential herb for phlegm and retained fluid. It is commonly indicated for warming phlegm-fluid retention, warming yang to induce diuresis and storing water in the sun. 4. Warming essence and removing arthralgia: it can warm and unblock meridians, pungent and dispersing for dispelling wind and eliminating dampness; the medicine can warm and dredge the interior, dispel cold and relieve pain, and can lead various wind-damp-dispelling medicines to directly reach the focus, thereby achieving the effect of killing three birds with one stone. 5. Warming and dredging chest yang: it is a good herb for warming chest and yang because it is pungent and can pass through, warm and strengthen yang. It is commonly indicated for chest impediment and palpitation. 6. Warming middle energizer to dispel cold: it is pungent, sweet and warm, pungent in flavor and capable of moving qi, warm in property and dispelling cold, sweet in flavor and tonifying deficiency, middle yang in healthy and moving cold to eliminate pathogenic factors and stop pain. 7. Stimulating the menstrual flow and eliminating abdominal mass: it has the actions of warming and activating blood vessels, directing the leading herbs directly to the affected part, and alleviating and eliminating mass, so it is more effective. 8. Flat-impact reverse-fall: gui Zhi warms heart and kidney yang and reduces the pathogenic cold, so it has the action of pacifying and descending adverse flow of qi.

Native copper: it is a herb that enters blood and circulates blood and connects tendons and bones. Has effects in promoting fracture healing and resisting fungi.

Minor mandible: this herb is pungent, bitter and neutral in nature; it enters liver, kidney and lung meridians. The efficacy is mainly as follows: the product has effects of dispelling pathogenic wind and removing dampness, dispelling blood stasis, and reuniting bones and muscles; it is commonly indicated for wind-damp arthralgia, irregular menstruation, postpartum abdominal pain, traumatic swelling and pain, fracture, etc.

Rhizoma arisaematis: this herb is bitter and pungent in flavor, warm in nature and toxic; it enters lung, liver and spleen meridians. The efficacy is mainly as follows: the product has effects of eliminating dampness and phlegm, dispelling pathogenic wind and relieving spasm, resolving hard mass and detumescence; it is commonly used for cough due to stubborn phlegm, wind-phlegm vertigo, apoplexy, facial distortion, hemiplegia, epilepsy, infantile convulsion, tetanus, etc.

Diverse wormwood herb: being bitter in flavor and warm in nature, it enters heart and spleen meridians. The efficacy is mainly as follows: the product has effects in removing blood stasis, dredging channels, healing sore, relieving swelling, healing wound, stopping bleeding, promoting digestion, removing food stagnation, activating spleen, and stimulating appetite; it is commonly indicated for amenorrhea, abdominal distension, postpartum blood stasis, traumatic injury, bleeding due to incised wound, inflammation and swelling due to carbuncle.

The compatibility mechanism of the medicine formula of the invention is as follows: in the medicine, saffron, dragon's blood, pangolin scales and pseudo-ginseng are monarch medicines; radix Aconiti Preparata, radix Aconiti Kusnezoffii Preparata, ramulus Sambuci Williamsii and radix Clematidis as ministerial drugs; cortex Acanthopanacis, rhizoma Drynariae, rhizoma homalomenae and ramulus Cinnamomi as adjuvant drugs; pyritum, herba Centellae, rhizoma arisaematis and herba Artemisiae Anomalae are used as guiding drugs. The prescription of the invention has reasonable monarch, minister, assistant and guide compatibility, combines the medicines, achieves the effect of penetrating from inside to outside, and has good treatment effect on orthopedic diseases such as lumbar disc herniation, hyperplasia of neck, shoulder, waist and knee, ankylosing spondylitis, lumbar spondylolisthesis and the like.

The application method of the pain bone-knitting plaster of the invention comprises the following steps: the plaster is pasted on the affected part and fixed by medical adhesive plaster; the patch is replaced once every 5-7 days, and is usually attached for one treatment course 5-7 times.

The invention has the following positive beneficial effects:

1. the invention mainly treats the root cause according to the theory of the holistic concept of the traditional Chinese medicine, and overcomes the defect that western medicines treat the symptoms and do not treat the root causes. The plaster of the invention is used for external application and has the characteristics of convenient use and quick response; can be used for treating prolapse of lumbar intervertebral disc, hyperosteogeny of neck, shoulder, waist and knee, ankylosing spondylitis, and lumbar spondylolisthesis. Relieving pain for patients and avoiding sequelae caused by operation. Through statistics of treatment and application of 360 patients, the cure rate reaches 88.6%, the total effective rate is 97.7%, the curative effect is reliable, and the effect is obvious.

2. For years, the plaster is used for treating a plurality of patients with lumbar intervertebral disc protrusion, hyperplasia of neck, shoulder, waist and knee, ankylosing spondylitis and lumbar spondylolisthesis hyperplasia, the treatment conditions of 360 patients are counted in detail, and the statistical data are detailed in table 1.

。

General diagnostic criteria for lumbar disc herniation:

1) leg pain is more severe than lumbago, typical radicular sciatica;

2) paresthesia of the lower extremities, allodynia of single nerve roots in the legs or feet (lumbar 5, sacral 1 or lumbar 4 spinal nerve root distribution areas);

3) lower lumbar spinal nerve root involvement signs: the straight leg elevation test is less than 50 degrees; the straight leg elevation strengthening test is positive; positive in the Jian Gao test. One of the three signs must be positive.

4) Two of four types of muscular atrophy, muscle weakness, paresthesia and reflex change in the neurological physical examination were positive.

5) The examination of spinal cord radiography, lumbar intervertebral disc CT flat scan or lumbar nuclear magnetic resonance is positive result and is consistent with the clinical symptoms and physical signs of affected nerve roots.

The diagnosis of the lumbar intervertebral disc protrusion can be made only if the five standards are positive.

Diagnostic criteria for ankylosing spondylitis (new york criteria revised by the american college of rheumatology 1984):

(1) clinical criteria are as follows:

lower back pain persists for at least 3 months, with relief after activity (rather than rest).

Secondly, the movement of the lumbar vertebra in the vertical and horizontal planes is limited.

And the chest expansion degree is reduced compared with that of normal people of the same age and sex.

(2) The diagnosis standard is as follows:

has unilateral III-IV grade or II-III grade X-ray sacroiliac arthritis, and at least 1 of 3 clinical standard strips.

The activity should be diagnosed when diagnosing ankylosing spondylitis. Currently, the common indicators for clinically judging ankylosing spondylitis activities are: morning stiffness is more than or equal to 30 minutes; sleep is affected by pain and stiffness; peripheral arthritis; ESR is more than or equal to 30mm/1h (Weishi method); CRP is more than or equal to 20 mg/L; 1gA is more than or equal to 3.9 g/L; spinal pain; chest pain during normal breathing or pain or stiffness during neck movement; pain in the buttocks during the day or at night.

Lumbar spondylolisthesis: usually, a certain vertebral body is displaced forwards or backwards, which is commonly seen in lumbar vertebra, and lumbar spondylolisthesis in China is one of the common diseases in orthopedics. Currently, lumbar spondylolisthesis is divided into 6 categories of dysplasia (including high-grade and low-grade dysplasia), isthmus, degeneration, trauma and pathology. In addition, isthmus fissuring and degeneration are common. The incidence rate of lumbar spondylolisthesis varies according to race and region, is 4-6% in Europe and approximately 4.7-5% of the population in China; the spondylolisthesis caused by the isthmus fissure accounts for about 15%, and the degenerative lumbar spondylolisthesis accounts for about 35%. The age of onset of lumbar spondylolisthesis in China is more than 20-50 years old, accounting for 85%; more men than women develop the disease, and the ratio of men to women is 29: 1. the common parts of lumbar spondylolisthesis are L4-L5 and L5-S1, wherein the incidence rate of the lumbar 5 vertebral body is 82-90 percent

Judging the spondylolisthesis and hyperplasia of lumbar vertebrae:

type I: dysplasia; is a congenital defect of the superior articular process of the sacrum 1 or the lumbar vertebra 5, and can not prevent the anterior spondylolisthesis of the lumbar vertebra 5.

Type II: isthmus type; it is a stress fracture or extension of the isthmus (between the upper and lower articular processes) that causes the upper articular process to move forward along with the upper lumbar vertebrae.

Type III: deforming; the slippage occurs due to the instability of articular processes and intervertebral discs as a result of long-term degeneration, but to a lesser extent.

And IV, type: the type of trauma; it is a fracture of vertebral pedicle, vertebral plate and articular process caused by acute trauma, and this type is rare.

Type V: the pathological type; it is a systemic disease such as osteogenesis imperfecta, osteitis deformans, etc.

Hyperplasia of neck, shoulder, waist and knee: it also belongs to hyperosteogeny, and the hyperosteogeny is a disease with the main symptoms of local joint, muscle and ligament movement disorder caused by pathological hyperosteogeny and accompanying pain. It can occur in cervical vertebra, lumbar vertebra, joints and calcaneus. The disease is usually seen in middle-aged and old people over 40 years old and in the working of weight bearing, long standing and sitting, and the disease of joints and vertebras with large range of motion is common. The causes of hyperosteogeny are unknown so far, and are mostly in the category of senile degenerative diseases. The basic understanding is that the pathogenesis is caused by the induction of exogenous factors on the basis of endogenous factors. At present, the western medicine adopts non-hormone anti-inflammatory and analgesic drugs, physical therapy and surgical treatment, and has certain effect on relieving symptoms, but no special effective therapy exists so far.

The treatment method comprises the following steps:

the plaster is pasted on the affected part for treating patients with lumbar disc herniation, hyperplasia of neck, shoulder, waist and knee, ankylosing spondylitis and lumbar spondylolisthesis hyperplasia; the plaster adopts the following medicine formula: 15-25 g of saffron, 25-35 g of dragon's blood, 20-30 g of pangolin scales, 40-60 g of pseudo-ginseng, 30-45 g of monkshood, 30-45 g of kusnezoff monkshood root, 35-50 g of elderberry, 40-55 g of clematis root, 40-50 g of cortex acanthopanacis, 40-50 g of rhizoma drynariae, 30-45 g of homalomena rhizoma, 40-50 g of cassia twig, 30-45 g of native copper, 40-55 g of lesser spider, 40-55 g of arisaema tuber and 45-65 g of artemisia anomala.

The application method of the plaster comprises the following steps: the plaster is pasted on the affected part and fixed by medical adhesive plaster; the patch is replaced once every 5-7 days, and is usually attached for one treatment course 5-7 times.

The judgment standard of the syndrome curative effect is as follows:

(1) the clinical cure is as follows: clinical symptoms and physical signs of the traditional Chinese medicine disappear or basically disappear, and the syndrome integral is reduced by more than or equal to 95 percent;

after the treatment course is finished, the symptoms and physical signs disappear, and the main indexes are recovered or close to normal after the examination.

(2) The effect is shown: the clinical symptoms and physical signs of the traditional Chinese medicine are obviously improved, and the syndrome integral is reduced by more than or equal to 70 percent. Treatment course

After the treatment, symptoms and physical signs basically disappear, and main indexes are obviously improved through examination.

(3) The method has the following advantages: the clinical symptoms and physical signs of the traditional Chinese medicine are improved, and the syndrome integral is reduced by more than or equal to 30 percent. Treatment course

After the treatment, the symptoms and physical signs are reduced, and the main indexes are also improved through examination.

(4) And (4) invalidation: the clinical symptoms and physical signs of the traditional Chinese medicine are not obviously improved or even aggravated, and the syndrome integral is reduced

Less than 30 percent. After the treatment course is finished, the symptoms and physical signs are not obviously improved.

As shown in Table 1, the plaster of the invention has the advantages of remarkable treatment effect and total effective rate of 97.7 percent when used for treating 360 cases of orthopedic patients.

Typical cases are:

1. in the age of 50, a woman in high altitude has the lumbar disc herniation and has the right leg nerve compressed for years, and the patient cannot walk due to the pain at present. The plaster is pasted on an affected part for treatment, after 3 courses of treatment, the symptoms basically disappear, and then the plaster is continuously used for 2 courses of treatment, the symptoms disappear, and the plaster basically recovers to be normal through X-ray examination and is cured. The disease does not relapse after 3 years of return visit.

2. When one of old men is 26 years old and suffers from lumbar intervertebral disc protrusion for 3 years, the old man presses nerves of both legs, loses normal walking function and cannot sit for a long time. The plaster is stuck on an affected part for treatment, after 4 treatment courses, various symptoms basically disappear, and the detection shows that the prominent symptoms disappear; then continuously using for 2 courses for consolidation and healing. After 1 year, no relapse occurs after return visit.

3. In Li, a woman in 64 years old, the patient has prolapse of lumbar intervertebral disc, and severe lumbar spondylolisthesis. The plaster is pasted on the affected part for treatment, and after 4 half treatment courses, the symptoms such as pain, numbness and the like basically disappear and the affected part is healed. Then continue to be consolidated using 2 courses. After examination, various symptoms disappear and the normal state is recovered. After one year, the return visit is carried out without relapse.

4. Guo is 48 years old, and has cervical spondylosis for years, and the treatment effect is not ideal when hospitalization is carried out in a traditional Chinese medicine hospital in Henan province. Later, the doctor visits everywhere, and the dizziness is severe and the vomit is severe, and the doctor cannot walk normally. The plaster is pasted on an affected part for treatment, and the vomit is stopped and the dizziness is relieved after 4 treatment courses; after 2 treatment courses, the plaster of the invention is continuously used, and the plaster is checked to be recovered to normal and cured. After 2 years, no relapse occurs after return visit.

5. Suzhong, male, age 54, suffered from cervical spondylosis for years, lost the labor capacity and was treated in many places, but the treatment effect is not ideal. The plaster is applied to the affected part for treatment after the patient sees a doctor, and after 4 treatment courses, various symptoms basically disappear; after 2 treatment courses, the plaster of the invention is continuously used, and the plaster is checked to be recovered to normal and cured. After 3 years, no relapse occurs after return visit.

6. Li in Li, female, age 58, protrusion of 2 cervical vertebra, slippage of 1 cervical vertebra, dizziness and numbness of both hands. The plaster is applied to the affected part for treatment, and after 4 treatment courses, the plaster is examined, slipped, reset and protruded normally. After 1 year, no relapse occurs after return visit.

7. Some Lu, male, 45 years old, has lumbar disc herniation for many years, and at present, cannot walk normally and cannot go to work. The effect is not good after multiple treatments. After the treatment, the plaster is pasted on the affected part for treatment, and after 3 treatment courses, various symptoms are obviously relieved; after the plaster is continuously used for treating for 2 courses, the plaster is checked to be normal. After 2 years, no relapse occurs after return visit.

8. If a certain plum is old at 85 years, a woman suffers from osteonecrosis, cannot walk, and has no obvious effect after being treated at multiple places. The plaster is pasted on the affected part for treatment after the treatment, and after 5 treatment courses, various symptoms basically disappear and the patient can normally walk; the plaster can be used for curing after 2 courses of treatment. After half a year, all the people are normal.

9. Li A certain, male, age 58, suffered from spondylitis for many years, back pain was intolerable, and after many treatments, the treatment was repeated. After the treatment, the plaster is pasted on the affected part for treatment, and after 3 treatment courses, various symptoms basically disappear; the plaster can be used for curing after 2 courses of treatment. After half a year, all the people are normal.

10. Liu Yi, male, age 44, mainly complained of "movement of neck, waist and double hips is limited for 10 years", movement of cervical vertebra, lumbar vertebra and lumbar vertebra is limited, squatting is not possible, waist and back are stiff, intolerance of cold, nocturia, gastric cavity fullness and loose stool; the diagnosis is 'ankylosing spondylitis'. After the treatment, the plaster is pasted on the affected part for treatment, and after 3 treatment courses, various symptoms basically disappear; the plaster is continuously used for 1 course of treatment for consolidation. After half a year, all the people are normal.

11. Zhangyi, male, 19 years old, 2 years old, spinal column night pain, stiffness, obvious morning, hypodynamia, emaciation, long-term intermittent low fever, limited activity of cervical vertebra, thoracic vertebra and lumbar vertebra, positive pelvis extrusion separation test; the diagnosis is 'ankylosing spondylitis'. After the treatment, the plaster is pasted on the affected part for treatment, and after 3 treatment courses, various symptoms basically disappear; the plaster is continuously used for 1 course of treatment for consolidation. After 1 year, all the plants are normal.

12. Sinus, male, 23 years old, 3 years old, spinal pain, obvious morning stiffness, accompanied by hypodynamia, emaciation, mild anemia, persistent low fever, limited forward and backward movement of the waist, positive pelvic crush separation test. The diagnosis is 'ankylosing spondylitis'. After the treatment, the plaster is applied to the affected part for treatment, and after 3 treatment courses, various symptoms basically disappear. After 1 year, all the plants are normal.

13. Some Guo is a woman who is 65 years old and has pain in both knees for more than 3 years, so the woman can walk reluctantly. The treatment is also carried out at a plurality of places, but the treatment effect is not ideal and is repeated. After the treatment, the plaster is pasted on the affected part for treatment, and after 3 treatment courses, various symptoms basically disappear; the plaster can be used for curing after 2 courses of treatment. After 1 year, all the plants are normal.

14. In men, 72 years old, there is a blood tumor in the spine, which presses the nerves, and the pain is hard to endure due to numbness of the legs, legs and feet. The patients go to local hospitals for surgical treatment, but the hemangioma can not be removed after the operation; subsequently, Beijing is removed for treatment, but the hemangioma still cannot be removed by surgery. After the treatment, the plaster is pasted on the affected part for treatment, and after 5 treatment courses, various symptoms basically disappear; the plaster can be used for curing after 2 courses of treatment. The hemangioma disappeared by examination. After 1 year, all the plants are normal.

15. Wu-Chi, female, age 76, has had lumbar disc herniation for more than 3 years, hyperplasia, stenosis, spondylolisthesis, and spinal degeneration. After the treatment, the plaster is pasted on the affected part for treatment, and after 5 treatment courses, various symptoms basically disappear; the plaster can be used for curing after 2 courses of treatment. After inspection, the affected part is restored to normal. After 1 year, all the plants are normal.

Fourthly, the specific implementation mode:

the present invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.

Example 1:

the pain bone-knitting plaster is prepared from, by weight, 20g of saffron crocus, 30g of dragon's blood, 25g of pangolin scales, 50g of pseudo-ginseng, 38g of prepared monkshood, 38g of prepared kusnezoff monkshood root, 42g of elderberry, 48g of clematis root, 46g of cortex acanthopanacis, 45g of rhizoma drynariae, 38g of homalomena rhizoma, 47g of cassia twig, 40g of native copper, 48g of small spider, 48g of rhizoma arisaematis and 55g of artemisia anomala.

Example 2:

the pain bone-knitting plaster is prepared from the following raw materials, by weight, 18g of saffron, 28g of dragon's blood, 22g of pangolin scales, 45g of pseudo-ginseng, 35g of prepared monkshood, 35g of prepared kusnezoff monkshood root, 38g of elderberry, 45g of clematis root, 45g of cortex acanthopanacis, 42g of rhizoma drynariae, 35g of homalomena rhizoma, 45g of cassia twig, 36g of native copper, 45g of lesser spider, 45g of rhizoma arisaematis and 50g of artemisia anomala.

Example 3:

the pain bone-knitting plaster is prepared from the following raw materials, by weight, 22g of saffron, 32g of dragon's blood, 26g of pangolin scales, 55g of pseudo-ginseng, 42g of prepared monkshood, 42g of prepared kusnezoff monkshood root, 45g of elderberry, 50g of clematis root, 48g of cortex acanthopanacis, 46g of rhizoma drynariae, 40g of homalomena rhizoma, 48g of cassia twig, 45g of native copper, 52g of lesser spider, 50g of rhizoma arisaematis and 60g of artemisia anomala.

Example 4:

the pain bone-knitting plaster is prepared from, by weight g, 21g of saffron crocus, 29g of dragon's blood, 24g of pangolin scales, 52g of pseudo-ginseng, 40g of prepared common monkshood mother root, 36g of prepared kusnezoff monkshood root, 40g of elderberry, 49g of clematis root, 47g of cortex acanthopanacis, 43g of rhizoma drynariae, 36g of homalomena rhizoma, 46g of cassia twig, 38g of native copper, 50g of lesser spider, 46g of rhizoma arisaematis and 58g of artemisia anomala.

Example 5:

the pain bone-knitting plaster is prepared from 19g of saffron crocus, 31g of dragon's blood, 23g of pangolin scales, 48g of pseudo-ginseng, 36g of prepared common monkshood mother root, 40g of prepared kusnezoff monkshood root, 42g of elderberry, 46g of clematis root, 46g of cortex acanthopanacis, 44g of drynaria rhizome, 38g of homalomena rhizoma, 46g of cassia twig, 42g of native copper, 48g of lesser spider, 48g of rhizoma arisaematis and 52g of diverse wormwood herb.

Example 6:

the pain bone-knitting plaster is prepared from the following raw materials, by weight, 15g of saffron, 25g of dragon's blood, 20g of pangolin scales, 40g of pseudo-ginseng, 30g of prepared common monkshood mother root, 30g of prepared kusnezoff monkshood root, 35g of sambucus williamsii hance, 40g of clematis root, 40g of cortex acanthopanacis, 40g of rhizoma drynariae, 30g of homalomena rhizoma, 40g of cassia twig, 30g of native copper, 40g of lesser spider, 40g of rhizoma arisaematis and 45 g.

Example 7:

the pain bone-knitting plaster is prepared from, by weight, 20g of saffron crocus, 30g of dragon's blood, 25g of pangolin scales, 50g of pseudo-ginseng, 40g of prepared monkshood, 40g of prepared kusnezoff monkshood root, 45g of elderberry, 45g of clematis root, 45g of cortex acanthopanacis, 45g of rhizoma drynariae, 38g of homalomena rhizoma, 45g of cassia twig, 38g of native copper, 50g of lesser spider, 50g of rhizoma arisaematis and 55g of artemisia anomala.

Example 8:

the pain bone-knitting plaster is prepared from 25g of saffron, 35g of dragon's blood, 30g of pangolin scales, 60g of pseudo-ginseng, 45g of prepared monkshood, 45g of prepared kusnezoff monkshood root, 50g of elderberry, 55g of clematis root, 50g of cortex acanthopanacis, 50g of rhizoma drynariae, 45g of homalomena rhizoma, 50g of cassia twig, 45g of native copper, 55g of lesser spider, 55g of rhizoma arisaematis and 65g of artemisia anomala.

Example 9:

the method for decocting the pain bone-knitting plaster disclosed by the embodiment 1-8 of the invention comprises the following detailed steps:

a. firstly, weighing various raw material medicines according to the raw material composition proportion of the pain bone-knitting plaster in any one of embodiments 1 to 8 for later use;

b. b, uniformly mixing the various raw materials weighed in the step a, pouring the raw materials into 2500g of sesame oil for heating, boiling, controlling the temperature to be 40-60 ℃, decocting for 60 minutes, continuously stirring in the decocting process, and filtering out dregs after decocting to obtain cream oil;

c. b, heating the paste oil obtained in the step b to boiling, slowly adding red lead, wherein the mass ratio of the plaster to the red lead is 2:1, after the red lead is added, decocting for 1.5 hours at the temperature of 40-60 ℃, continuously stirring in the decocting process, and decocting to obtain the plaster;

d. and d, pouring the plaster obtained in the step c into water, soaking for 24 hours, taking out after soaking, and spreading on cloth to obtain the pain bone-knitting plaster.

Claims (2)

1. A pain bone-knitting plaster is characterized in that: the pain bone-knitting plaster is prepared from the following raw materials, by weight, 15-25 g of saffron, 25-35 g of dragon's blood, 20-30 g of pangolin, 40-60 g of pseudo-ginseng, 30-45 g of prepared monkshood, 30-45 g of prepared kusnezoff monkshood root, 35-50 g of elderberry, 40-55 g of clematis root, 40-50 g of cortex acanthopanacis, 40-50 g of drynaria rhizome, 30-45 g of homalomena occulta, 40-50 g of cassia twig, 30-45 g of native copper, 40-55 g of lesser spider, 40-55 g of arisaema tuber and 45-65 g of diverse wormwood herb;

the pain bone-knitting plaster is prepared by decocting the following steps:

a. firstly, weighing various raw material medicines according to the raw material composition proportion of the pain bone-knitting plaster for later use;

b. uniformly mixing the raw materials weighed in the step a, pouring the mixture into 2000-3000 g of sesame oil, heating, boiling, decocting at 40-60 ℃ for 40-80 minutes while continuously stirring, and filtering out dregs to obtain cream oil;

c. b, heating the paste oil obtained in the step b to boiling, slowly adding red lead, wherein the mass ratio of the plaster to the red lead is 2:1, after the red lead is added, decocting for 1-1.5 hours at the temperature of 40-60 ℃, continuously stirring in the decocting process, and decocting to obtain the plaster;

d. and d, pouring the plaster obtained in the step c into water, soaking for 20-24 hours, taking out after soaking, and spreading on cloth to obtain the pain bone-knitting plaster.

2. A pain bone-setting plaster according to claim 1, characterized in that: the pain bone-knitting plaster is prepared from 18-22 g of saffron, 28-32 g of dragon's blood, 22-26 g of pangolin scales, 45-55 g of pseudo-ginseng, 35-42 g of prepared monkshood, 35-42 g of prepared kusnezoff monkshood root, 38-45 g of elderberry, 45-50 g of clematis root, 45-48 g of cortex acanthopanacis, 42-46 g of drynaria rhizome, 35-40 g of homalomena occulta, 45-48 g of cassia twig, 36-45 g of native copper, 45-52 g of lesser spider, 45-50 g of arisaema cum bile and 50-60 g of artemisia anomala.