CN105031811B - 用于葡萄糖调节的方法和系统 - Google Patents

用于葡萄糖调节的方法和系统 Download PDF

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Publication number
CN105031811B
CN105031811B CN201510277948.6A CN201510277948A CN105031811B CN 105031811 B CN105031811 B CN 105031811B CN 201510277948 A CN201510277948 A CN 201510277948A CN 105031811 B CN105031811 B CN 105031811B
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China
Prior art keywords
nerve
time
signal
electrical signal
pulse generator
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Expired - Fee Related
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CN201510277948.6A
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English (en)
Chinese (zh)
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CN105031811A (zh
Inventor
阿诺德·W·桑顿
丹尼斯·D·金
马克·B·克努森
凯瑟琳·S·特威登
理查德·R·威尔逊
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Vyome Holdings Inc
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Enteromedics Inc
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Electrotherapy Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201510277948.6A 2008-04-04 2009-04-03 用于葡萄糖调节的方法和系统 Expired - Fee Related CN105031811B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4257508P 2008-04-04 2008-04-04
US61/042,575 2008-04-04
CN200980120949.2A CN102056645B (zh) 2008-04-04 2009-04-03 用于葡萄糖调节的方法和系统

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CN105031811A CN105031811A (zh) 2015-11-11
CN105031811B true CN105031811B (zh) 2017-09-08

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CN200980120949.2A Expired - Fee Related CN102056645B (zh) 2008-04-04 2009-04-03 用于葡萄糖调节的方法和系统

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US (5) US8483830B2 (enExample)
EP (2) EP3047874B1 (enExample)
JP (4) JP5486588B2 (enExample)
CN (2) CN105031811B (enExample)
AU (1) AU2009231601B2 (enExample)
HK (1) HK1217306A1 (enExample)
WO (1) WO2009124233A1 (enExample)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
PT2359808E (pt) 2006-08-09 2013-08-28 Intarcia Therapeutics Inc Sistemas de entrega osmótica e montagens de pistão
ES2402172T3 (es) 2007-04-23 2013-04-29 Intarcia Therapeutics, Inc Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos
US8391970B2 (en) * 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
CN105031811B (zh) * 2008-04-04 2017-09-08 安特罗麦迪克斯公司 用于葡萄糖调节的方法和系统
US8868215B2 (en) * 2008-07-11 2014-10-21 Gep Technology, Inc. Apparatus and methods for minimally invasive obesity treatment
US20100274312A1 (en) 2009-04-22 2010-10-28 Konstantinos Alataris Spinal cord modulation for inducing paresthetic and anesthetic effects, and associated systems and methods
US8255057B2 (en) 2009-01-29 2012-08-28 Nevro Corporation Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
ES2452484T3 (es) 2008-11-18 2014-04-01 Setpoint Medical Corporation Dispositivos para optimizar la colocación de electrodos para la estimulación antiinflamatoria
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) * 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
CN102573986B (zh) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 用于无导线刺激器的具有袋部的神经封套
EP3735944A1 (en) * 2009-09-28 2020-11-11 Intarcia Therapeutics, Inc. Rapid establishment and/or termination of substantial steady-state drug delivery
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
CN102821814B (zh) 2009-12-23 2015-07-15 赛博恩特医疗器械公司 用于治疗慢性炎症的神经刺激设备和系统
US8825164B2 (en) 2010-06-11 2014-09-02 Enteromedics Inc. Neural modulation devices and methods
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
WO2012154865A2 (en) 2011-05-09 2012-11-15 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
WO2013036880A1 (en) 2011-09-08 2013-03-14 Thacker James R Selective high frequency spinal cord modulation for inhibiting pain, including cephalic and/or total body pain with reduced side effects, and associated systems and methods
EP2788078B1 (en) * 2011-12-09 2020-09-02 Metavention, Inc. Therapeutic neuromodulation of the hepatic system
EP2822648A2 (en) * 2012-03-07 2015-01-14 Enteromedics Inc. Devices for regulation of blood pressure and heart rate
US20150111918A1 (en) 2012-03-08 2015-04-23 Medtronic Ardian Luxembourg S.a.r.l Immune system neuromodulation and associated systems and methods
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US9536449B2 (en) 2013-05-23 2017-01-03 Medibotics Llc Smart watch and food utensil for monitoring food consumption
US9442100B2 (en) 2013-12-18 2016-09-13 Medibotics Llc Caloric intake measuring system using spectroscopic and 3D imaging analysis
US9042596B2 (en) 2012-06-14 2015-05-26 Medibotics Llc Willpower watch (TM)—a wearable food consumption monitor
US9254099B2 (en) 2013-05-23 2016-02-09 Medibotics Llc Smart watch and food-imaging member for monitoring food consumption
US8504161B1 (en) * 2012-08-07 2013-08-06 Medtronic, Inc. Modulate vagal signals to reduce inflammation
US10496797B2 (en) 2012-08-30 2019-12-03 Medtronic Minimed, Inc. Blood glucose validation for a closed-loop operating mode of an insulin infusion system
US9662445B2 (en) 2012-08-30 2017-05-30 Medtronic Minimed, Inc. Regulating entry into a closed-loop operating mode of an insulin infusion system
US10130767B2 (en) 2012-08-30 2018-11-20 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9878096B2 (en) 2012-08-30 2018-01-30 Medtronic Minimed, Inc. Generation of target glucose values for a closed-loop operating mode of an insulin infusion system
US9526834B2 (en) 2012-08-30 2016-12-27 Medtronic Minimed, Inc. Safeguarding measures for a closed-loop insulin infusion system
CA2882300C (en) * 2012-08-30 2020-12-29 Medtronic Minimed, Inc. Safeguarding techniques for a closed-loop insulin infusion system
WO2014116938A1 (en) * 2013-01-28 2014-07-31 Enteromedics Inc. Energy efficient neuromodulation
US9529385B2 (en) 2013-05-23 2016-12-27 Medibotics Llc Smart watch and human-to-computer interface for monitoring food consumption
US20160128767A1 (en) 2013-06-05 2016-05-12 Metavention, Inc. Modulation of targeted nerve fibers
US9895539B1 (en) 2013-06-10 2018-02-20 Nevro Corp. Methods and systems for disease treatment using electrical stimulation
CN109998483B (zh) 2013-09-16 2023-02-28 斯坦福大学董事会 用于电磁能量生成的多元件耦合器
US10149978B1 (en) 2013-11-07 2018-12-11 Nevro Corp. Spinal cord modulation for inhibiting pain via short pulse width waveforms, and associated systems and methods
US20160336813A1 (en) 2015-05-15 2016-11-17 NeuSpera Medical Inc. Midfield coupler
EP4074273A1 (en) 2014-05-18 2022-10-19 NeuSpera Medical Inc. Midfield coupler
CN104147699A (zh) * 2014-07-31 2014-11-19 李军 一种用于治疗2型糖尿病的腹腔神经丛电刺激系统
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
CA2965780A1 (en) * 2014-11-03 2016-05-12 Galvani Bioelectronics Limited Neuromodulation device
AU2015358385B2 (en) 2014-12-03 2020-09-03 Medtronic Ireland Manufacturing Unlimited Company Systems and methods for modulating nerves or other tissue
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
HK1246712A1 (zh) 2015-02-20 2018-09-14 The Feinstein Institute For Medical Research 神经刺激治疗疾病及病症
WO2016141184A1 (en) * 2015-03-03 2016-09-09 Georgia Tech Research Corporation Glucose regulation via electrical stimulation of nerves innervating the liver
KR102650751B1 (ko) 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
JP2017000437A (ja) * 2015-06-10 2017-01-05 オリンパス株式会社 心筋再生装置
US11318310B1 (en) 2015-10-26 2022-05-03 Nevro Corp. Neuromodulation for altering autonomic functions, and associated systems and methods
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
CN108882885A (zh) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 迷走神经刺激的控制
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
WO2017127758A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
AU2017211121B2 (en) 2016-01-25 2022-02-24 Nevro Corp. Treatment of congestive heart failure with electrical stimulation, and associated systems and methods
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
WO2017197272A1 (en) 2016-05-13 2017-11-16 Georgia Tech Research Corporation Systems, methods, and devices for neuromodulation
CN109310743A (zh) 2016-05-16 2019-02-05 因塔西亚制药公司 胰高血糖素受体选择性多肽及其使用方法
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
US9955882B2 (en) * 2016-08-31 2018-05-01 Medtronic Xomed, Inc. System to monitor neural integrity
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
US11872371B2 (en) 2017-04-20 2024-01-16 The Feinstein Institutes For Medical Research Systems and methods for real-time monitoring of physiological biomarkers through nerve signals and uses thereof
WO2019036470A1 (en) 2017-08-14 2019-02-21 Setpoint Medical Corporation TESTING TEST FOR STIMULATION OF NERVE WAVE
WO2019173525A1 (en) * 2018-03-09 2019-09-12 General Electric Company Ultrasound neuromodulation techniques
CN112423838A (zh) * 2018-04-12 2021-02-26 重塑生命科学股份有限公司 用于改善的血糖控制系统和方法的同时多部位迷走神经的神经调节
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
US11590352B2 (en) 2019-01-29 2023-02-28 Nevro Corp. Ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods
WO2020168136A1 (en) * 2019-02-13 2020-08-20 Avent, Inc Portable electrical stimulation system and method
US12029577B2 (en) * 2019-03-12 2024-07-09 GE Precision Healthcare LLC Neuromodulation to target glucose transporter and/or incretin pathways
US12343535B2 (en) 2019-04-12 2025-07-01 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
CN110064130A (zh) * 2019-04-17 2019-07-30 上海黎欧生物科技有限公司 一种胆囊起搏器
AU2020257261B2 (en) * 2019-04-18 2025-11-13 Reshape Lifesciences, Inc. Methods and systems for neural regulation
JP2023512447A (ja) 2020-01-13 2023-03-27 ザ ファインスタイン インスティチューツ フォー メディカル リサーチ 脾臓への高密度集束超音波刺激による出血及び出血性疾患の治療
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
EP4313273A4 (en) * 2021-04-01 2025-01-22 ReShape Lifesciences, Inc. NEUROMODULATION SYSTEM AND METHOD FOR TREATING A HYPOGLYCEMIC CONDITION
US12444497B2 (en) 2021-05-17 2025-10-14 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
WO2022251366A1 (en) 2021-05-25 2022-12-01 Nevro Corp. Modified high frequency neuromodulation signals, and associated systems and methods
US20230355976A1 (en) * 2022-05-05 2023-11-09 Medtronic, Inc. Neuromodulation for treatment of neonatal chronic hyperinsulinism

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124012A (zh) * 2004-12-27 2008-02-13 范因斯坦医学研究院 通过电刺激迷走神经治疗炎症性疾病
CN101272821A (zh) * 2005-07-28 2008-09-24 赛博罗尼克斯公司 治疗胰腺疾病的自主神经刺激

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231988A (en) 1991-08-09 1993-08-03 Cyberonics, Inc. Treatment of endocrine disorders by nerve stimulation
US5540730A (en) 1995-06-06 1996-07-30 Cyberonics, Inc. Treatment of motility disorders by nerve stimulation
US7599736B2 (en) * 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
US20040249421A1 (en) 2000-09-13 2004-12-09 Impulse Dynamics Nv Blood glucose level control
IL129032A (en) * 1999-03-17 2006-12-31 Moshe Dudai Stomach strap
US6885888B2 (en) 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
CA2417005A1 (en) * 2000-07-20 2002-01-31 Bristol Myers Squibb Company Regulators of ppar.delta.(.beta.) and their use in the treatment of obesity and insulin resistance
US6832114B1 (en) 2000-11-21 2004-12-14 Advanced Bionics Corporation Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes
US7167751B1 (en) * 2001-03-01 2007-01-23 Advanced Bionics Corporation Method of using a fully implantable miniature neurostimulator for vagus nerve stimulation
US7702394B2 (en) 2001-05-01 2010-04-20 Intrapace, Inc. Responsive gastric stimulator
US6928320B2 (en) 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US20060116736A1 (en) 2001-07-23 2006-06-01 Dilorenzo Daniel J Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity
US7702386B2 (en) * 2002-03-22 2010-04-20 Leptos Biomedical, Inc. Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes
US7239912B2 (en) * 2002-03-22 2007-07-03 Leptos Biomedical, Inc. Electric modulation of sympathetic nervous system
US7689277B2 (en) * 2002-03-22 2010-03-30 Leptos Biomedical, Inc. Neural stimulation for treatment of metabolic syndrome and type 2 diabetes
US7689276B2 (en) 2002-09-13 2010-03-30 Leptos Biomedical, Inc. Dynamic nerve stimulation for treatment of disorders
AU2003284018A1 (en) * 2002-10-04 2004-05-04 Microchips, Inc. Medical device for neural stimulation and controlled drug delivery
US20040172084A1 (en) * 2003-02-03 2004-09-02 Knudson Mark B. Method and apparatus for treatment of gastro-esophageal reflux disease (GERD)
US7613515B2 (en) * 2003-02-03 2009-11-03 Enteromedics Inc. High frequency vagal blockage therapy
US7844338B2 (en) * 2003-02-03 2010-11-30 Enteromedics Inc. High frequency obesity treatment
US7444183B2 (en) * 2003-02-03 2008-10-28 Enteromedics, Inc. Intraluminal electrode apparatus and method
US7620454B2 (en) * 2003-05-19 2009-11-17 Medtronic, Inc. Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof
US7149574B2 (en) * 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
EP1641522B1 (en) * 2003-06-20 2012-12-19 Metacure Limited Gastrointestinal apparatus for detecting a change in posture
JP4960700B2 (ja) 2003-07-21 2012-06-27 メタキュアー リミティド 疾患を治療し、血糖を制御する際に使用するための胃腸処置方法および装置
US20070060971A1 (en) * 2003-07-21 2007-03-15 Ofer Glasberg Hepatic device for treatment or glucose detection
US7711432B2 (en) * 2004-07-26 2010-05-04 Advanced Neuromodulation Systems, Inc. Stimulation system and method for treating a neurological disorder
US8214047B2 (en) 2004-09-27 2012-07-03 Advanced Neuromodulation Systems, Inc. Method of using spinal cord stimulation to treat gastrointestinal and/or eating disorders or conditions
US7613520B2 (en) 2004-10-21 2009-11-03 Advanced Neuromodulation Systems, Inc. Spinal cord stimulation to treat auditory dysfunction
US20060122099A1 (en) * 2004-12-08 2006-06-08 Aoki Thomas T Method for infusing insulin to a subject to improve impaired total body tissue glucose processing
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9339190B2 (en) 2005-02-17 2016-05-17 Metacure Limited Charger with data transfer capabilities
US7561923B2 (en) 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US20070016262A1 (en) 2005-07-13 2007-01-18 Betastim, Ltd. Gi and pancreatic device for treating obesity and diabetes
US7620455B2 (en) * 2005-10-25 2009-11-17 Cyberonics, Inc. Cranial nerve stimulation to treat eating disorders
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
US7747324B2 (en) * 2005-11-10 2010-06-29 Electrocore Llc Electrical stimulation treatment of bronchial constriction
JP5108787B2 (ja) * 2006-01-23 2012-12-26 リハブトロニクス インコーポレイテッド 埋め込まれた受動導体を介して電流を体組織へルーティングする方法
EP1981584B1 (en) 2006-02-03 2015-05-13 Interventional Autonomics Corporation Intravascular device for neuromodulation
US7711430B2 (en) 2006-02-10 2010-05-04 Electrocore Llc Methods and apparatus for treating anaphylaxis using electrical modulation
US8187297B2 (en) 2006-04-19 2012-05-29 Vibsynt, Inc. Devices and methods for treatment of obesity
WO2007137026A2 (en) 2006-05-18 2007-11-29 Cedars-Sinai Medical Center Electrical stimulation of the lower esophageal sphincter
US8634930B2 (en) * 2006-06-30 2014-01-21 Cardiac Pacemakers, Inc. System for providing diabetic therapy
US8068918B2 (en) * 2007-03-09 2011-11-29 Enteromedics Inc. Remote monitoring and control of implantable devices
US20080281365A1 (en) * 2007-05-09 2008-11-13 Tweden Katherine S Neural signal duty cycle
US20080300646A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Treatment of cardiomyopathy, heart failure and cardiac ischemia using stimulation induced secretion of glp-1
US20080300648A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Treatment of cardiomyopathy, heart failure and cardiac ischemia using stimulation induced secretion of glp-1
US8532787B2 (en) 2007-05-31 2013-09-10 Enteromedics Inc. Implantable therapy system having multiple operating modes
US20080300647A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Treatment of cardiomyopathy, heart failure and cardiac ischemia using stimulation induced secretion of glp-1
US20080300645A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Treatment of cardiomyopathy, heart failure and cardiac ischemia using stimulation induced secretion of glp-1
EP2254462B1 (en) 2007-11-12 2015-05-20 Daniel J. Dilorenzo Apparatus for programming of autonomic neuromodulation for the treatment of obesity
WO2009102969A1 (en) * 2008-02-14 2009-08-20 Enteromedics, Inc. Treatment of excess weight by neural downregulation in combination with compositions
CN105031811B (zh) 2008-04-04 2017-09-08 安特罗麦迪克斯公司 用于葡萄糖调节的方法和系统
US20090254133A1 (en) * 2008-04-07 2009-10-08 Wendell Keith F Method for treatment of diabetes by electrostimulatioin
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
EP2334374A4 (en) 2008-08-26 2011-12-28 Janssen Biotech Inc STIMULATING THE RELEASE OF A SATIETY HORMONE
DE202010017584U1 (de) 2009-05-08 2012-02-29 Université Libre de Bruxelles Gastrointestinale Vorrichtung
US20120259389A1 (en) 2009-09-21 2012-10-11 Warren Starkebaum Treatment of postprandial hyperglycemia by gastric electrical stimulation
US8934975B2 (en) 2010-02-01 2015-01-13 Metacure Limited Gastrointestinal electrical therapy
EP2575958B1 (en) 2010-05-27 2017-10-18 Ndi Medical, LLC Waveform shapes for treating neurological disorders optimized for energy efficiency
AU2011282294B9 (en) 2010-07-19 2014-09-25 Cardiac Pacemakers, Inc. Minimally invasive lead system for vagus nerve stimulation
WO2012044472A2 (en) 2010-10-01 2012-04-05 Indiana University Research & Technology Corporation Long term vagal nerve stimulation for therapeutic and diagnostic treatment
WO2012060874A2 (en) 2010-11-01 2012-05-10 Udaya Sankar Devanaboyina Methods for diagnosis and treatment of disorders of the gastrointestinal tract. and apparatus for use therewith
EP2635344B1 (en) 2010-11-03 2015-07-08 The Cleveland Clinic Foundation Apparatus for energy efficient stimulation
WO2012083259A2 (en) 2010-12-17 2012-06-21 Neural Diabetes Foundation, Inc. Method, system and apparatus for control of pancreatic beta cell function to improve glucose homeostatis and insulin production

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101124012A (zh) * 2004-12-27 2008-02-13 范因斯坦医学研究院 通过电刺激迷走神经治疗炎症性疾病
CN101272821A (zh) * 2005-07-28 2008-09-24 赛博罗尼克斯公司 治疗胰腺疾病的自主神经刺激

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