CN105031567A - Traditional Chinese medicinal capsules for treating infantile heat-toxin constipation - Google Patents
Traditional Chinese medicinal capsules for treating infantile heat-toxin constipation Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicinal capsules for treating infantile heat-toxin constipation. The traditional Chinese medicinal capsules are prepared from the following traditional Chinese medicinal materials in parts by weight: 2 parts of wild peppers, 3 parts of dried gingers, 9 parts of codonopsis pilosula, 6 parts of dandelions, 8 parts of licorice, 10 parts of milk skin, 6 parts of cordia dichotoma fruits, 4 parts of bitter oranges, 6 parts of rhizoma atractylodis macrocephalae, 8 parts of etlingera yunnanense, 5 parts of rhamnus ussuriensis barks, 6 parts of pegia nitida colobr, 5 parts of sapium baccatum, 6 parts of wild string beans, 6 parts of aizoon stonecrop herb and 6 parts of pine pollen disruption powder. A clinical experiment shows that the remarkable effect of treating infantile heat-toxin constipation can be achieved by selecting proper medicinal materials and a proper proportion and the traditional Chinese medicinal capsules are safe and free of toxic or side effects.
Description
Technical field
the present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of the constipation of children's's pyretic toxicity.
Background technology
children's's internal organs in physiology are tender and lovely, and shape gas does not fill, and the material of body and function are not all grown perfect, in addition children's tremble with fear temperature can not self-regulated, diet is not known hungry full, often damage lung, spleen, kidney dirty, cause pyretic toxicity astriction.Treatment for the constipation of children's's pyretic toxicity still lacks the quick-acting medicine had no side effect of generally recognized as safe at present.
Summary of the invention
the present invention aims to provide and is a kind ofly used for the treatment of Chinese medicinal capsule of children's's pyretic toxicity constipation and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating the constipation of children's's pyretic toxicity, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions:
be used for the treatment of a Chinese medicinal capsule for children's's pyretic toxicity constipation, be prepared from by the Chinese crude drug of following weight proportion: 2 parts, Pericarpium Zanthoxyli, Rhizoma Zingiberis 3 parts, Radix Codonopsis 9 parts, Herba Taraxaci 6 parts, 8 parts, Radix Glycyrrhizae, skin on boiled milk 10 parts, fruit of Cordia dichotoma Forst. f. 6 parts, Fructus Aurantii 4 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Etlingera yunnanense 8 parts, 5 parts, Radix Rhamni ussriensis bark, poison creeper 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 6 parts.
preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
the peel that Pericarpium Zanthoxyli [source] is rutaceae Pericarpium Zanthoxyli.[nature and flavor] are pungent, temperature, poisonous.[function cures mainly] warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separates fish raw meat poison.Control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.
rhizoma Zingiberis [source] this product is the dry rhizome of zingiber.[nature and flavor] are pungent, hot.[return through] returns spleen, stomach, kidney, the heart, lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
radix Codonopsis [source] this product is the dry root of Campanulaceae Radix Codonopsis.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
herba Taraxaci [source] this product is feverfew Herba Taraxaci or the dry herb belonging to several plants together.[nature and flavor] are bitter, sweet, cold.[return through] returns liver, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
the processed goods of skin on boiled milk [source] Babalus bubalis L. or cattle milk surface oils and fats.[nature and flavor] are damp and hot, sweet in the mouth.[function cures mainly] raw humidogene heat, nourishing the lung to arrest cough, mend the fertile body of body, wet one's whistle sore throat relieving, mends stomach intestine moistening, anticorrosion wound healing, dispelling wind for relieving itching.Cure mainly dry cold or black gallbladder matter disease, as dryness of the lung dry cough, the empty body of body is thin, dry pharynx hoarseness, cold insufficiency of stomach, dryness of the intestine constipation, various skin trauma, psoriasis, tinea capitis.
the dry mature fruit that fruit of Cordia dichotoma Forst. f. [source] is comfrey rag wood.[nature and flavor] one-level is damp and hot.[function cures mainly] raw humidogene heat, ripe abnormal savda, lung moistening wets one's whistle, relieving cough and resolving phlegm, and sore throat relieving quenches the thirst, relieving constipation diuresis.Cure mainly dry cold or black gallbladder matter disease, as dryness of the pharynx and larynx, be diligent sexyly to emit, dry cough pertinacious phlegm, aphonia is thirsty, dysuria, defecates not smooth.
fructus Aurantii [source] this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.[nature and flavor] are bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
the Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
the rhizome that Etlingera yunnanense [source] is zingiberaceous plant Etlingera yunnanense.[nature and flavor] mildly bitter flavor, sweet, gas delicate fragrance, property is put down.[function cures mainly] Qinghuo Jiedu, diuresis, mends native stomach invigorating, ventilation relieving distension.The puckery pain of main smelting urine heat, stomach wrist distending pain, nausea and vomiting, anorexia, diarrhoea, heatstroke.
the bark that Radix Rhamni ussriensis bark [source] is Rhamnaceae plant Radix Rhamni ussriensis.[nature and flavor] are bitter; Cold.[function cures mainly] clearing away heat and loosing the bowels.Main constipation with heat retention.
the Herb that poison creeper [source] is Anacardiaceae plant poison creeper or root.[nature and flavor] bitter in the mouth, micro-acid.Warm in nature.[function cures mainly] heat-clearing and toxic substances removing, cough-relieving, reducing swelling and alleviating pain, except wind is antipruritic.Cure mainly cough, (joint stuffiness, lumbago, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) is irritated for rheumatic fever arthromyodynia, limbs joint red and swollen heat pain.
breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
the root that Sapium baccatum Roxb [source] is euphorbia plant Sapium baccatum Roxb.[nature and flavor] taste is micro-puckery, and property is put down.[function cures mainly] adjusts benefit four tower, and regulating menstruation and activating blood, mends native stomach invigorating, promoting the circulation of QI to relieve pain.How sick, weak cure mainly and have a delicate constitution, menstruation point is adjusted, dysmenorrhea, amenorrhea, abdominal distention, anorexia.
the seed of the wild Semen Canavaliae of wild Semen Canavaliae [source] leguminous plant and root.[nature and flavor] taste is sweet.Property is put down.Enter four towers.[function cures mainly] adjusts benefit four tower, Qinghuo Jiedu, killing parasites for relieving itching.Cure mainly have a delicate constitution how sick, weak, anorexia, insomnia, furuncle carbuncle furuncle abscess, skin pruritus, macule, scabies, eczema.
herba Sedi Aizoon [source] medical material Ji Yuan: be root or the herb of crassulaceae plants Herba sedi kamtschatici, horizontal root Herba sedi kamtschatici.[nature and flavor] put down; Sweet; Micro-acid.[return through] heart; Liver; Spleen channel.[function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances.Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment children's pyretic toxicity constipation cure rate high and safe without toxic side effect, and can related complication be prevented.Monarch, four natures and five flavors of drug lifting is particular about between prescription Chinese crude drug of the present invention.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have compatibility between the formula medical material of certain combination principle rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.Fang Zhong: Pericarpium Zanthoxyli, Rhizoma Zingiberis, Radix Codonopsis share, and merit builds middle-jiao yang, function of the spleen and stomach in temperature, and tonify deficiency cold expelling, is just accord with pathogenesis, and can promote that gastrointestinal shrinks, and regulatory function is disorderly, makes enterokinesia recover normal, improves constipation; Help with the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii two medicine 5 use, one rushes down a benefit again, and one walks one keeps, and one anxious one delays, and mutually restricts, keeps the good and eliminates the evil, refinforce each other, to reach tonify without causing stagnation, disappear and just do not hinder, spleen invigorating stomach strengthening, promoting digestion and removing stagnation, the merit of relieving distension and oppression; And help Radix Codonopsis spleen reinforcing to help fortune with Radix Glycyrrhizae; Skin on boiled milk and Radix Rhamni ussriensis bark share can mend stomach intestine moistening, clearing away heat and loosing the bowels; Herba Taraxaci and fruit of Cordia dichotoma Forst. f. share and cure mainly pyretic toxicity constipation, relieving stranguria by diuresis; Etlingera yunnanense ventilation relieving distension; Again with poison creeper heat-clearing and toxic substances removing; Therefore middle burnt transformation and transportation of the spleen and stomach is recovered, then large intestine conduction function recovers normal, and constipation is eliminated.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: Pericarpium Zanthoxyli 2g, Rhizoma Zingiberis 3g, Radix Codonopsis 9g, Herba Taraxaci 6g, Radix Glycyrrhizae 8g, skin on boiled milk 10g, fruit of Cordia dichotoma Forst. f. 6g, Fructus Aurantii 4g, Rhizoma Atractylodis Macrocephalae 6g, Etlingera yunnanense 8g, Radix Rhamni ussriensis bark 5g, poison creeper 6g, Sapium baccatum Roxb 5g, wild Semen Canavaliae 6g, Herba Sedi Aizoon 6g, breaking cellular wall Pollen Pini 6g.
preparation method is: (1) mixes after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, take 4 courses for the treatment of continuously.
clinical data:
1, case selection:
selected the routine clinical observation of children's's pyretic toxicity constipation patient 62 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets children's's pyretic toxicity constipation diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 36 example, matched group 26 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 7 days, is 1 course for the treatment of.
matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
4 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: every day defecation 1 time, just matter is soft, in amount, without stomachache.
(2) take a turn for the better: defecation 4 ~ 5 times weekly, just matter is partially hard, and amount is large, time have stomachache.
(3) do not heal: sings and symptoms is without change.
4, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 28 examples, and take a turn for the better 6 examples, and do not heal 2 examples, and be almost recovered rate 77.7%, total effective rate 94.4%.Improvement and the infant that is almost recovered are followed the tracks of and follows up a case by regular visits to 3 months, recurrence 3 example, relapse rate 8.3%.
be almost recovered in matched group 10 examples, and take a turn for the better 9 examples, and do not heal 7 examples, and be almost recovered rate 38.5%, total effective rate 73.1%.Improvement and the infant that is almost recovered are followed the tracks of and follows up a case by regular visits to 3 months, recurrence 7 example, relapse rate 26.9%.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.Relevant Chinese medicine also exists rectification of name, different name, calls and be commonly called as, and the concrete medical material referred to all can be known by existing open source literature and network, also can with the substitute in the medical material generation of close effect.For the person of ordinary skill of the art, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal capsule of children's's pyretic toxicity constipation, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: 2 parts, Pericarpium Zanthoxyli, Rhizoma Zingiberis 3 parts, Radix Codonopsis 9 parts, Herba Taraxaci 6 parts, 8 parts, Radix Glycyrrhizae, skin on boiled milk 10 parts, fruit of Cordia dichotoma Forst. f. 6 parts, Fructus Aurantii 4 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Etlingera yunnanense 8 parts, 5 parts, Radix Rhamni ussriensis bark, poison creeper 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 6 parts.
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| CN102698227A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese medicine for treating constipation |
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| CN102698227A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese medicine for treating constipation |
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| 赵新成等: "蒲公英有治疗小儿热毒便秘作用", 《吉林中医药》 * |
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Application publication date: 20151111 |