CN104984284A - Traditional Chinese medicine capsule for treating childhood functional constipation - Google Patents
Traditional Chinese medicine capsule for treating childhood functional constipation Download PDFInfo
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- CN104984284A CN104984284A CN201510371142.3A CN201510371142A CN104984284A CN 104984284 A CN104984284 A CN 104984284A CN 201510371142 A CN201510371142 A CN 201510371142A CN 104984284 A CN104984284 A CN 104984284A
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Abstract
The invention discloses a traditional Chinese medicine capsule for treating childhood functional constipation. The traditional Chinese medicine capsule is prepared from the following traditional Chinese medicinal materials in parts by weight: 2 parts of xanthoxyli fructus, 3 parts of rhizoma zingiberis, 9 parts of radix codonopsis, 6 parts of radix aucklandiae, 8 parts of radix glycyrrhizae, 10 parts of skin on boiled milk, 6 parts of root of ipomoea purga Hayne, 4 parts of fructus aurantii, 6 parts of atractylodes macrocephala, 8 parts of platycodon gradiflorus, 5 parts of trona, 6 parts of pegia nitida, 5 parts of sapium baccatum, 6 parts of cana valia virosa, 6 parts of sedum aizoon and 6 parts of pine pollen disruption powder. Clinical experiments show that through selecting appropriate herbs and a matching ratio, the traditional Chinese medicine capsule provided by the invention has remarkable curative effects on treating childhood functional constipation, and is safe and free of toxic and side effects.
Description
Technical field
the present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of Functional Constipation in Children.
Background technology
constipation is sick not normal at large intestine conduction function, dirtyly has substantial connection with taste, liver, kidney are all.It is " rear unfavorable " that "Nei Jing" is found a great convenience secret, and " difficulty in defecation " thinks relevant by cold-damp with spleen.Treatise on Febrile Diseases, " Medical Treasures of the Golden Chamber " are called " spleen-constipation ", " closing ", " constipation of YIN type ", " accumulation of heat ", think with cold, heat, the stagnation of QI are relevant.This weakness of spleen and stomach of children's, the nondigestible thing such as greasy in eating cold and uncooked food excessively melon and fruit, taste catch cold, and middle Jiao is impaired, and intestinal loses warm, transmit unable therefore constipation.Functional Constipation in Children refers to it is not the constipation caused by apparatus factors.Treatment for Functional Constipation in Children still lacks the quick-acting medicine had no side effect of generally recognized as safe at present.
Summary of the invention
the present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of Functional Constipation in Children and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating Functional Constipation in Children, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions:
be used for the treatment of a Chinese medicinal capsule for Functional Constipation in Children, be prepared from by the Chinese crude drug of following weight proportion: 2 parts, Pericarpium Zanthoxyli, Rhizoma Zingiberis 3 parts, Radix Codonopsis 9 parts, the Radix Aucklandiae 6 parts, 8 parts, Radix Glycyrrhizae, skin on boiled milk 10 parts, radix jalalae root 6 parts, Fructus Aurantii 4 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, purple Radix Platycodonis 8 parts, Tronae 5 parts, poison creeper 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 6 parts.
preparation method is: (1) mixes after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
the peel that Pericarpium Zanthoxyli [source] is rutaceae Pericarpium Zanthoxyli.[nature and flavor] are pungent, temperature, poisonous.[function cures mainly] warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separates fish raw meat poison.Control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.
rhizoma Zingiberis [source] this product is the dry rhizome of zingiber.[nature and flavor] are pungent, hot.[return through] returns spleen, stomach, kidney, the heart, lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
radix Codonopsis [source] this product is the dry root of Campanulaceae Radix Codonopsis.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
the dry root of the Radix Aucklandiae [source] the feverfew Radix Aucklandiae.[nature and flavor] are pungent, bitter, temperature.[return through] returns spleen, stomach, large intestine, three burnt, gallbladder meridians.[function cures mainly] promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.
radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
the processed goods of skin on boiled milk [source] Babalus bubalis L. or cattle milk surface oils and fats.[nature and flavor] are damp and hot, sweet in the mouth.[function cures mainly] raw humidogene heat, nourishing the lung to arrest cough, mend the fertile body of body, wet one's whistle sore throat relieving, mends stomach intestine moistening, anticorrosion wound healing, dispelling wind for relieving itching.Cure mainly dry cold or black gallbladder matter disease, as dryness of the lung dry cough, the empty body of body is thin, dry pharynx hoarseness, cold insufficiency of stomach, dryness of the intestine constipation, various skin trauma, psoriasis, tinea capitis.
the dried root that radix jalalae root [source] is convolvulaceous plant Bryonia dioica.[nature and flavor] secondary is xeothermic, sweet in the mouth.[function cures mainly] raw dry heat-dissipating, attacks and rushes down dampness, cold-dispelling pain-relieving, detumescent of relieving oedema or abdominal distension through diuresis or purgation, stop old coughing, move back old heat, anthelmintic.Cure mainly raw property or kill liquid matter disease, as constipation, habitual constipation, hydrosarca, bowel obstruction, old is had a headache, cold heating, insane disease, aching pain in waist and back, sciatica, paralysis, facial paralysis, arthralgia, oldly coughs more than, and old heat is not moved back, and intestinal is infested.
fructus Aurantii [source] this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.[nature and flavor] are bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
the Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
the purple Radix Platycodonis of purple Radix Platycodonis [source] Ranunculaceae, is used as medicine with root.[nature and flavor] are pungent, cool.[function cures mainly] clearing away heat and expelling pathogen in the exterior, yang invigorating.Cure mainly headache due to pathogenic wind-heat, watery diarrhea.
tronae [source] is boil containing the alkaline earth of sodium carbonate to form or at salt water lakeside Nature creating.[nature and flavor] salty in the mouth, twenty, bitter, property is put down.[function cures mainly] to be dispelled Ba Dagan, is helped digestion, relieving constipation, only rotten, removing toxic substances.Cure mainly dyspepsia, stomach Ba Da does disease, constipation, women's mass formed by blood stasis, amenorrhea, placenta retention, skin infection.
the Herb that poison creeper [source] is Anacardiaceae plant poison creeper or root.[nature and flavor] bitter in the mouth, micro-acid.Warm in nature.[function cures mainly] heat-clearing and toxic substances removing, cough-relieving, reducing swelling and alleviating pain, except wind is antipruritic.Cure mainly cough, (joint stuffiness, lumbago, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) is irritated for rheumatic fever arthromyodynia, limbs joint red and swollen heat pain.
breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment Functional Constipation in Children cure rate high and safe without toxic side effect, and can related complication be prevented.Monarch, four natures and five flavors of drug lifting is particular about between prescription Chinese crude drug of the present invention.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have compatibility between the formula medical material of certain combination principle rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.Fang Zhong: Pericarpium Zanthoxyli, Rhizoma Zingiberis, Radix Codonopsis share, and merit builds middle-jiao yang, function of the spleen and stomach in temperature, and tonify deficiency cold expelling, is just accord with pathogenesis, and can promote that gastrointestinal shrinks, and regulatory function is disorderly, makes enterokinesia recover normal, improves constipation.Radix Codonopsis spleen reinforcing is helped to help fortune with the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae again; Skin on boiled milk and Tronae share can mend stomach intestine moistening, and help digestion relieving constipation; The Radix Aucklandiae, Fructus Aurantii sending down the abnormal ascending QI alleviating distention in middle-JIAO; Again with purple Radix Platycodonis, poison creeper heat-clearing and toxic substances removing; Therefore middle burnt transformation and transportation of the spleen and stomach is recovered, then large intestine conduction function recovers normal, and constipation is eliminated.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: Pericarpium Zanthoxyli 2g, Rhizoma Zingiberis 3g, Radix Codonopsis 9g, Radix Aucklandiae 6g, Radix Glycyrrhizae 8g, skin on boiled milk 10g, radix jalalae root 6g, Fructus Aurantii 4g, Rhizoma Atractylodis Macrocephalae 6g, purple Radix Platycodonis 8g, Tronae 5g, poison creeper 6g, Sapium baccatum Roxb 5g, wild Semen Canavaliae 6g, Herba Sedi Aizoon 6g, breaking cellular wall Pollen Pini 6g.Preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, take 4 courses for the treatment of continuously.
clinical data:
1, case selection:
selected the routine clinical observation of Functional Constipation in Children patient 98 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets Functional Constipation in Children diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 72 example, matched group 26 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 2, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 7 days, is 1 course for the treatment of.
matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
4 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: every day defecation 1 time, just matter is soft, in amount, without stomachache.
(2) take a turn for the better: defecation 4 ~ 5 times weekly, just matter is partially hard, and amount is large, time have stomachache.
(3) do not heal: sings and symptoms is without change.
4, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 54 examples, and take a turn for the better 12 examples, and do not heal 6 examples, and be almost recovered rate 75%, total effective rate 91.7%.
be almost recovered in matched group 10 examples, and take a turn for the better 9 examples, and do not heal 7 examples, and be almost recovered rate 38.5%, total effective rate 73.1%.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.Relevant Chinese medicine also exists rectification of name, different name, calls and be commonly called as, and the concrete medical material referred to all can be known by existing open source literature and network, also can with the substitute in the medical material generation of close effect.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal capsule of Functional Constipation in Children, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: 2 parts, Pericarpium Zanthoxyli, Rhizoma Zingiberis 3 parts, Radix Codonopsis 9 parts, the Radix Aucklandiae 6 parts, 8 parts, Radix Glycyrrhizae, skin on boiled milk 10 parts, radix jalalae root 6 parts, Fructus Aurantii 4 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, purple Radix Platycodonis 8 parts, Tronae 5 parts, poison creeper 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 6 parts.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698227A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese medicine for treating constipation |
| CN103285168A (en) * | 2013-05-06 | 2013-09-11 | 安徽省颍上县中医院 | Traditional Chinese medicine for treating constipation by using Fraxinus malacophylla |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698227A (en) * | 2012-05-26 | 2012-10-03 | 苑丕吉 | Chinese medicine for treating constipation |
| CN103285168A (en) * | 2013-05-06 | 2013-09-11 | 安徽省颍上县中医院 | Traditional Chinese medicine for treating constipation by using Fraxinus malacophylla |
Non-Patent Citations (2)
| Title |
|---|
| 石艳红等: "养阴清热汤治疗小儿功能性便秘37例", 《山东中医药大学学报》 * |
| 闫慧敏: "小儿功能性便秘研究进展", 《实用儿科临床杂志》 * |
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