CN105031459A - Traditional Chinese medicinal capsules for treating autumn diarrhea in children - Google Patents
Traditional Chinese medicinal capsules for treating autumn diarrhea in children Download PDFInfo
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- CN105031459A CN105031459A CN201510370032.5A CN201510370032A CN105031459A CN 105031459 A CN105031459 A CN 105031459A CN 201510370032 A CN201510370032 A CN 201510370032A CN 105031459 A CN105031459 A CN 105031459A
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Abstract
The invention discloses traditional Chinese medicinal capsules for treating autumn diarrhea in children. The traditional Chinese medicinal capsules are prepared from the following traditional Chinese medicinal materials in parts by weight: 12 parts of semen lepidii sativa, 6 parts of morus nigra, 7 parts of scutellaria baicalensis, 8 parts of coptis chinensis, 6 parts of licorice, 8 parts of polyporus umbellatus, 9 parts of plantain seeds, 6 parts of atractylodes lancea, 8 parts of etlingera yunnanense, 6 parts of abutilon indicum, 6 parts of halite, 4 parts of pine needles, 6 parts of pine pollen disruption powder, 5 parts of sapium baccatum, 6 parts of wild string beans and 6 parts of aizoon stonecrop herb. A clinical experiment shows that the remarkable effect of treating autumn diarrhea in children can be achieved by selecting proper medicinal materials and a proper proportion and the traditional Chinese medicinal capsules are safe and free of toxic or side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of infantile autumn diarrhea.
Background technology
Infantile autumn diarrhea refers to the infantile diarrhea that rotavirus causes, how popular in the fall, therefore practises title " rotavirus enteritis ".Clinical show as diarrhoea more, to have a fever or with dehydration sign in various degree.During blood routine examination, numeration of leukocyte is general not high, and stool microscopy is based on Oil globule, and during stool electron microscopic examination, majority can find rotavirus.Primary disease belongs to the category that motherland's medical science " is had loose bowels ".Because children's is the body of immature yin and yang, QI and blood is not filled, and internal organs are real, and the spleen tending to insufficiency usually, if improper feeding or being invaded by exogenous pathogen, very easily cause spleen and stomach function not normal, therefore infantile diarrhea is based on weakness of the spleen and stomach, and pathogenic factor is secondary.Treatment for infantile autumn diarrhea still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
The present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of infantile autumn diarrhea and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating infantile autumn diarrhea, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicinal capsule for infantile autumn diarrhea, be prepared from by the Chinese crude drug of following weight proportion: cultivated pepperweed seed 12 parts, 6 parts, black Mulberry, Radix Scutellariae 7 parts, Rhizoma Coptidis 8 parts, 6 parts, Radix Glycyrrhizae, Polyporus 8 parts, Semen Plantaginis 9 parts, Rhizoma Atractylodis 6 parts, Etlingera yunnanense 8 parts, Herba abutili indici 6 parts, natural salt 6 parts, Folium Pini 4 parts, breaking cellular wall Pollen Pini 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts.
Preparation method is: (1) mixes after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
The dry mature seed that cultivated pepperweed seed [source] is crucifer cultivated pepperweed seed.[nature and flavor] secondary is xeothermic, and taste is micro-pungent.[function cures mainly] logical urine stimulates the menstrual flow, and speckle dispelling blazes.Raw dry heat-dissipating, appetizing replenishing essence, cold relieving tonifying YANG, resolving phlegm and relieving asthma, cures mainly raw property or lymphatic temperament disease, as poor appetite oligospermia, coldness of the body sexual impotence, abundant expectoration cough with asthma, urinary obstruction, not smooth through water, vitiligo, freckle etc.
The black that black Mulberry [source] is the black Mulberry of moraceae plants or erythrocarpus.[nature and flavor] sour in the mouth is micro-sweet.[function cures mainly] dysregulation blood matter and bile matter, the pharyngolaryngitis that disappears swells, and stops hot body fluid to flee in upper respiratory tract, quenches the thirst and increases food, except infections heals skin ulcer, clearing away heat to stop diarrhea.Cure mainly hot or blood matter and bile matter disease, as pharyngolaryngitis swells, thirsty poor appetite, oral ulcer, intestinal skin ulcer is hindered, hot diarrhoea and dysentery.
The dry root of Radix Scutellariae [source] labiate Radix Scutellariae.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The dry rhizome of Rhizoma Coptidis [source] ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Polyporus [source] this product is the dry sclerotia of On Polyporaceae Polyporus.[nature and flavor] are sweet, light, flat.[return through] returns kidney, urinary bladder channel.[function cures mainly] promoting diuresis to eliminate damp pathogen.For dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.
The dry mature seed of Semen Plantaginis [source] Plantaginaceae plant Herba Plantaginis.[nature and flavor] are sweet, are slightly cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
The dry rhizome of Rhizoma Atractylodis [source] feverfew Atractylodes lancea (Thunb.) DC..[function cures mainly] is drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Herba abutili indici [source] Malvaceae abutilon plant Herba abutili indici, is used as medicine with herb or root.Summer, autumn gather, and clean and dry.[function cures mainly] wind and heat dispersing, QI invigorating is sensible, diuresis of eliminating the phlegm.For flu, heat of a specified duration is not moved back, mumps, tinnitus, deaf, pulmonary tuberculosis, dysuria.
The halite crystallization that natural salt [source] is natural.[nature and flavor] sweet in the mouth, salty, warm in nature.[function cures mainly] warming middle-JIAO, helps digestion, and dry hertz of the Ba Da that dispels complies with, improving eyesight.Cure mainly cold syndrome of the stomach, dyspepsia, gastral cavilty distension, diarrhoea, conspicuous dizzy according to property.
Folium Pini [nature and flavor] is bitter; Warm in nature.[return through] heart; Spleen channel.[function cures mainly] dispeiling pathogenic wind and removing dampness; Killing parasites for relieving itching; Blood-promoting and mind-easing.Main air wets flaccidity syndrome and arthralgia syndrome; Foot gas; Eczema; Tinea; Rubella pruritus; Traumatic injury; Neurasthenia; Chronic nephritis; Hypertension.Preventing encephalitis, influenza.
The rhizome that Etlingera yunnanense [source] is zingiberaceous plant Etlingera yunnanense.[nature and flavor] mildly bitter flavor, sweet, gas delicate fragrance, property is put down.[function cures mainly] Qinghuo Jiedu, diuresis, mends native stomach invigorating, ventilation relieving distension.The puckery pain of main smelting urine heat, stomach wrist distending pain, nausea and vomiting, anorexia, diarrhoea, heatstroke.
Breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
The root that Sapium baccatum Roxb [source] is euphorbia plant Sapium baccatum Roxb.[nature and flavor] taste is micro-puckery, and property is put down.[function cures mainly] adjusts benefit four tower, and regulating menstruation and activating blood, mends native stomach invigorating, promoting the circulation of QI to relieve pain.How sick, weak cure mainly and have a delicate constitution, menstruation point is adjusted, dysmenorrhea, amenorrhea, abdominal distention, anorexia.
The seed of the wild Semen Canavaliae of wild Semen Canavaliae [source] leguminous plant and root.[nature and flavor] taste is sweet.Property is put down.Enter four towers.[function cures mainly] adjusts benefit four tower, Qinghuo Jiedu, killing parasites for relieving itching.Cure mainly have a delicate constitution how sick, weak, anorexia, insomnia, furuncle carbuncle furuncle abscess, skin pruritus, macule, scabies, eczema.
Herba Sedi Aizoon [source] medical material Ji Yuan: be root or the herb of crassulaceae plants Herba sedi kamtschatici, horizontal root Herba sedi kamtschatici.[nature and flavor] put down; Sweet; Micro-acid.[return through] heart; Liver; Spleen channel.[function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances.Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
Breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment infantile autumn diarrhea cure rate high and safe without toxic side effect, and can related complication be prevented.Monarch, four natures and five flavors of drug lifting is particular about between prescription Chinese crude drug of the present invention.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have compatibility between the formula medical material of certain combination principle rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.The soft intestinal relieving constipation of cultivated pepperweed seed in side, drive away helminth, black Mulberry clearing away heat to stop diarrhea is monarch drug altogether; Radix Scutellariae, Rhizoma Coptidis cooling intestine to eliminate heat, dampness removing and diarrhea-relieving, natural salt warming middle-JIAO helps digestion, and is ministerial drug altogether; In the sweet mitigation of Radix Glycyrrhizae, coordinating the actions of various ingredients in a prescription, thinks that assistant makes; Semen Plantaginis energy diuretic wets, point pure and impure and stopping leak; Herba abutili indici energy ascending the clear and descending the turbid; Rhizoma Atractylodis dampness activating the spleen; All medicines share the merit of playing clearing away heat-damp and promoting diuresis, only profit altogether, and treatment rotaviral enteritis also receives the effect that As the medicine took effect, the symptoms lessened, get instant result.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take cultivated pepperweed seed 12 grams, 6 grams, black Mulberry, Radix Scutellariae 7 grams, Rhizoma Coptidis 8 grams, 6 grams, Radix Glycyrrhizae, Polyporus 8 grams, Semen Plantaginis 9 grams, Rhizoma Atractylodis 6 grams, Etlingera yunnanense 8 grams, Herba abutili indici 6 grams, natural salt 6 grams, Folium Pini 4 grams, breaking cellular wall Pollen Pini 6 grams, Sapium baccatum Roxb 5 grams, wild Semen Canavaliae 6 grams, Herba Sedi Aizoon 6 grams.Preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal.It within 7 days, is 1 course for the treatment of.
Clinical data:
1, case selection:
Select the routine clinical observation of infantile autumn diarrhea patient 69 in my institute's diagnosis and treatment, clinical symptoms all meets infantile autumn diarrhea diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 37 example, matched group 32 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 7 days, is 1 course for the treatment of.
Matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
1-2 the course for the treatment of is treated in continuous smelting, contrasts two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: after treatment, times of defecation is normal, stool is shaped, healing time 3 ~ 5d.
(2) take a turn for the better: times of defecation reduces, stool turns thick, healing time 6 ~ 7d.
(3) do not heal: after treatment, times of defecation and character are without change.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 30 examples, and take a turn for the better 6 examples, and do not heal 1 example, and be almost recovered rate 81.1%, total effective rate 97.3%.Average cure time 3.6d.
Be almost recovered in matched group 11 examples, and take a turn for the better 15 examples, and do not heal 6 examples, and be almost recovered rate 34.3%, total effective rate 81.3%.Average cure time 5.7d.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.Relevant Chinese medicine also exists rectification of name, different name, calls and be commonly called as, and the concrete medical material referred to all can be known by existing open source literature and network, also can with the substitute in the medical material generation of close effect.For those of ordinary skill in the field, above-mentioned explanation basis can also make other changes in different forms.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal capsule of infantile autumn diarrhea, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: cultivated pepperweed seed 12 parts, 6 parts, black Mulberry, Radix Scutellariae 7 parts, Rhizoma Coptidis 8 parts, 6 parts, Radix Glycyrrhizae, Polyporus 8 parts, Semen Plantaginis 9 parts, Rhizoma Atractylodis 6 parts, Etlingera yunnanense 8 parts, Herba abutili indici 6 parts, natural salt 6 parts, Folium Pini 4 parts, breaking cellular wall Pollen Pini 6 parts, Sapium baccatum Roxb 5 parts, wild Semen Canavaliae 6 parts, Herba Sedi Aizoon 6 parts.
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Citations (3)
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| CN101152387A (en) * | 2007-09-24 | 2008-04-02 | 叶开洪 | Traditional Chinese medicine for treating infantile autumn diarrhea |
| CN101716237A (en) * | 2008-10-09 | 2010-06-02 | 孙蓉 | Traditional Chinese medicine composition for treating infantile diarrhea caused by rotavirus |
| CN103386100A (en) * | 2013-06-27 | 2013-11-13 | 王和清 | Autumn diarrhea paste |
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- 2015-06-30 CN CN201510370032.5A patent/CN105031459A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152387A (en) * | 2007-09-24 | 2008-04-02 | 叶开洪 | Traditional Chinese medicine for treating infantile autumn diarrhea |
| CN101716237A (en) * | 2008-10-09 | 2010-06-02 | 孙蓉 | Traditional Chinese medicine composition for treating infantile diarrhea caused by rotavirus |
| CN103386100A (en) * | 2013-06-27 | 2013-11-13 | 王和清 | Autumn diarrhea paste |
Non-Patent Citations (4)
| Title |
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| 云玉琴等: "抗菌抗病毒中草药的开发应用", 《山东畜牧兽医》 * |
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Application publication date: 20151111 |