CN104435556A - Traditional Chinese medicine capsules for treating skin ulcer and preparation method thereof - Google Patents
Traditional Chinese medicine capsules for treating skin ulcer and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses traditional Chinese medicine capsules for treating skin ulcer. The traditional Chinese medicine capsules are prepared from the following medicinal materials in parts by weight: 15 parts of honeysuckle flower, 15 parts of forsythia fruit, 20 parts of raw milkvetch root, 12 parts of mountain honey, 10 parts of Chuanxiong rhizome, 10 parts of lithocarpus polystachyus, 10 parts of shark liver, 18 parts of mayodendron igneum, 10 parts of gardenia, 20 parts of juniperus sabina, 10 parts of nakedflower beautyberry branchlet and leaf, 10 parts of dioscorea zingiberensis and 8 parts of dryopteris championii. Proved by clinical trials, through selecting appropriate medicinal materials and a proportioning ratio thereof, the traditional Chinese medicine capsules achieve a remarkable effect of effectively treating skin ulcer, are safe and are free from toxic or side effects, and recurrence is difficult.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of skin ulcer and preparation method thereof.
Background technology
Skin ulcer is surgery of Chinese medicine, the commonly encountered diseases of department of dermatologry, frequently-occurring disease, is take skin ulcer as main clinical manifestation, can not heals for Clinical symptoms for a long time, and Skin preparation, liquefaction, infection, necrosis are a kind of body surface disease of feature.The effective medicine of generally recognized as safe is still lacked at present for skin ulcer.
Summary of the invention
The present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of skin ulcer and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy of effectively treatment skin ulcer, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicinal capsule being used for the treatment of skin ulcer, is prepared from by the medical material of following weight proportion: Flos Lonicerae 12 ~ 15 parts, Fructus Forsythiae 12 ~ 15 parts, Radix Astragali 15 ~ 20 parts, mountain Mel 10 ~ 12 parts, Rhizoma Chuanxiong 8 ~ 10 parts, Folium Lithocarpi Polystachyi 8 ~ 10 parts, shark hepatic 8 ~ 10 parts, burn spend 12 ~ 18 parts, Fructus Gardeniae 8 ~ 10 parts, real 15 ~ 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 8 ~ 10 parts, Rhizoma Dioscoreae Zingiberensis 0 ~ 10 part, profit squama shield-fern 0 ~ 8 part.
As preferably, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts, profit squama shield-fern 8 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, profit squama shield-fern 8 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts, profit squama shield-fern 8 parts.
A kind of preparation method being used for the treatment of the Chinese medicinal capsule of skin ulcer, comprise the steps: that Flos Lonicerae, Fructus Forsythiae, Radix Astragali, mountain Mel, Rhizoma Chuanxiong, Folium Lithocarpi Polystachyi, baked wheaten cake flower, Fructus Gardeniae, savin reality, Folium et Ramulus Callicarpae nudiflorae, Rhizoma Dioscoreae Zingiberensis, profit squama shield-fern are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) shark hepatic pulverization is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Flos Lonicerae [source] this product is dry flower or the first flower opened of band of caprifoliaceae plant Radix Ophiopogonis.[nature and flavor] are sweet, cold.[return through] returns lung, the heart, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
The dry fruit of Fructus Forsythiae [source] Oleaceae plants Fructus Forsythiae.[nature and flavor] are bitter, are slightly cold.[return through] returns lung, the heart, small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
The dry root of Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
The dry root of mountain Mel [source] samphire mountain Mel.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Wine mountain Mel promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The dry rhizome of Rhizoma Chuanxiong [source] samphire Rhizoma Chuanxiong.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.
Folium Lithocarpi Polystachyi [source] is Fagaceae multiple-ear rock. leaf.Spring, the summer, autumn priming leaf, dry or using fresh herb.[function cures mainly] heat-clearing and toxic substances removing; Reduce phlegm; Dispel the wind; Blood pressure lowering.Main damp-heat dysentery; Cough due to lung-heat; Ulcer sores; Skin pruritus; Hypertension.
Shark hepatic [source] medical material Ji Yuan: the cod-liver oil that liver or liver for Hexanchiade animal homalocephalus notorhynchus maculatus and other sharks obtain through refinement.[nature and flavor] sweet in the mouth; Warm in nature.[function cures mainly] spleen invigorating QI invigorating; Nourishing the liver to improve visual acuity; Removing toxic substances sore.Dominant eye conjunctival xerosis; Nyctalopia; Osteomalacia; Burn and scald; Skin ulcer; Traumatic surface is not healed for a long time.
Burn root bark, bark and leaf that flower [source] is Bignoniaceae plant baked wheaten cake flower.[nature and flavor] bitter in the mouth, cool in nature.[function cures mainly] Qinghuo Jiedu, dispel the wind diuretic, killing parasites for relieving itching.Cure mainly toothache, arthralgia due to wind-cold-dampness disease, limbs joint swells and ache, joint stuffiness, and treat skin ulcer pain furuncle abscess, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) is irritated.
Fructus Gardeniae [nature and flavor] is bitter, cold.[return through] GUIXIN, lung, tri-jiao channel.[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
The cone that savin real [source] is Cupressaceae plant savin.The hot secondary of [nature and flavor] one-level is done, vinegar-pepper.[function cures mainly] raw dry heat-dissipating, cold relieving is stimulated the menstrual flow, and warming middle-JIAO falls apart gas, and inducing diuresis for treating stranguria syndrome, evacuation of pus granulation promoting, except speckle hair growth promoting.Cure mainly raw property or open-minded liquid matter disease, as cold amenorrhea, cold syndrome of the stomach abdominal distention not smooth through water, moist urine retention ascites, urine leaching are puckery, outmoded abscess, and tooth eye is rotten to the corn, alopecia areata black speck etc.
The leaf with twig that Folium et Ramulus Callicarpae nudiflorae [source] is Verbenaceae Callicarpa nudiflora.[function cures mainly] stops blooding, antiinflammatory, blood stasis dispelling, pain relieving.That controls that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause is hemorrhage, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia.
Rhizoma Dioscoreae Zingiberensis [source] Dioscoreaceae yam Rhizoma Dioscoreae Zingiberensis, is used as medicine with root stock.Spring and autumn excavates, and removes earth, dries.[function cures mainly] removing toxic substances and promoting subsidence of swelling.For the early stage non-ulceration of carbuncle furuncle, skin acute festering type infects, and soft tissue injury, honeybee stings insect bite.
Profit squama shield-fern [source] fern Dryopteridaceae profit squama shield-fern, is used as medicine with root stock.[function cures mainly] sore, removing toxic substances.Cure mainly skin infection to fester, do not close up for a long time, conjunctival congestion and swelling pain.
1, Chinese medicine preparation of the present invention for treatment skin ulcer cure rate high and safe without toxic side effect, and can related complication be prevented.Between formula medical material, compatibility is rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, make it reach medicine to remove to disease, and for prevent disease progress, in invade internal organs also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Radix Astragali 20 grams, mountain Mel 12 grams, Rhizoma Chuanxiong 10 grams, Folium Lithocarpi Polystachyi 10 grams, shark hepatic 10 grams, burn spend 18 grams, Fructus Gardeniae 10 grams, real 20 grams of savin, Folium et Ramulus Callicarpae nudiflorae 10 grams, Rhizoma Dioscoreae Zingiberensis 10 grams, profit squama shield-fern 8 grams.As follows: Flos Lonicerae, Fructus Forsythiae, Radix Astragali, mountain Mel, Rhizoma Chuanxiong, Folium Lithocarpi Polystachyi, baked wheaten cake flower, Fructus Gardeniae, savin reality, Folium et Ramulus Callicarpae nudiflorae, Rhizoma Dioscoreae Zingiberensis, profit squama shield-fern are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) shark hepatic pulverization is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal.
Embodiment 2
Take: Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Radix Astragali 20 grams, mountain Mel 12 grams, Rhizoma Chuanxiong 10 grams, Folium Lithocarpi Polystachyi 10 grams, shark hepatic 10 grams, burn spend 18 grams, Fructus Gardeniae 10 grams, real 20 grams of savin, Folium et Ramulus Callicarpae nudiflorae 10 grams, Rhizoma Dioscoreae Zingiberensis 10 grams, profit squama shield-fern 8 grams.
Preparation method, the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Take: Flos Lonicerae 15 grams, Fructus Forsythiae 15 grams, Radix Astragali 20 grams, mountain Mel 12 grams, Rhizoma Chuanxiong 10 grams, Folium Lithocarpi Polystachyi 10 grams, shark hepatic 10 grams, burn spend 18 grams, Fructus Gardeniae 10 grams, real 20 grams of savin, Folium et Ramulus Callicarpae nudiflorae 10 grams, Rhizoma Dioscoreae Zingiberensis 10 grams, profit squama shield-fern 8 grams, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge twice filtrate, concentrated.
Preparation method, the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
Selected the routine clinical observation of all kinds of skin ulcer patients 54 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets skin ulcer diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 27 example, matched group 27 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously.
Matched group adopts conventional antimicrobial ointment to be applied to ulcer wound surface, the course for the treatment of same treatment group.
3 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) cure: wound surface heals completely.
(2) take a turn for the better: wound surface is shown in that epithelial tissue is to central growth, skin injury reduces.
(3) do not heal: wound surface still has pus, skin injury is without reduction.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 20 examples, take a turn for the better 6 examples, and do not heal 1 example, cure rate 74%, total effective rate 96.3%.Laggard line trace in 6 months is followed up a case by regular visits to, all without recurrence.
Cure 10 examples in matched group, take a turn for the better 11 examples, and do not heal 6 examples, cure rate 37%, total effective rate 77.7%.Laggard line trace in 6 months is followed up a case by regular visits to, and has 3 example recurrences.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (6)
1. one kind is used for the treatment of the Chinese medicinal capsule of skin ulcer, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Lonicerae 12 ~ 15 parts, Fructus Forsythiae 12 ~ 15 parts, Radix Astragali 15 ~ 20 parts, mountain Mel 10 ~ 12 parts, Rhizoma Chuanxiong 8 ~ 10 parts, Folium Lithocarpi Polystachyi 8 ~ 10 parts, shark hepatic 8 ~ 10 parts, burn spend 12 ~ 18 parts, Fructus Gardeniae 8 ~ 10 parts, real 15 ~ 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 8 ~ 10 parts, Rhizoma Dioscoreae Zingiberensis 0 ~ 10 part, profit squama shield-fern 0 ~ 8 part.
2. a kind of Chinese medicinal capsule being used for the treatment of skin ulcer according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts, profit squama shield-fern 8 parts.
3. a kind of Chinese medicinal capsule being used for the treatment of skin ulcer according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, profit squama shield-fern 8 parts.
4. a kind of Chinese medicinal capsule being used for the treatment of skin ulcer according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts.
5. a kind of Chinese medicinal capsule being used for the treatment of skin ulcer according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Astragali 20 parts, mountain Mel 12 parts, Rhizoma Chuanxiong 10 parts, Folium Lithocarpi Polystachyi 10 parts, shark hepatic 10 parts, burn spend 18 parts, Fructus Gardeniae 10 parts, real 20 parts of savin, Folium et Ramulus Callicarpae nudiflorae 10 parts, Rhizoma Dioscoreae Zingiberensis 10 parts, profit squama shield-fern 8 parts.
6. one kind is used for the treatment of the preparation method of the Chinese medicinal capsule of skin ulcer, it is characterized in that, comprise the steps: that Flos Lonicerae, Fructus Forsythiae, Radix Astragali, mountain Mel, Rhizoma Chuanxiong, Folium Lithocarpi Polystachyi, baked wheaten cake flower, Fructus Gardeniae, savin reality, Folium et Ramulus Callicarpae nudiflorae, Rhizoma Dioscoreae Zingiberensis, profit squama shield-fern are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) shark hepatic pulverization is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
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Cited By (1)
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| CN104888195A (en) * | 2015-06-19 | 2015-09-09 | 易金阳 | Plant essence peptide composition for promoting wound healing |
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Application publication date: 20150325 |