CN104998054A - Traditional Chinese medicine preparation for treating constipation - Google Patents
Traditional Chinese medicine preparation for treating constipation Download PDFInfo
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- CN104998054A CN104998054A CN201510526468.9A CN201510526468A CN104998054A CN 104998054 A CN104998054 A CN 104998054A CN 201510526468 A CN201510526468 A CN 201510526468A CN 104998054 A CN104998054 A CN 104998054A
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Abstract
The invention provides a traditional Chinese medicine preparation for treating constipation, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine preparation comprises the following ingredients in parts by weight: 7 to 13 parts of astragalus, 7 to 13 parts of cistanche, 7 to 13 parts of snake gourd seeds, 12 to 18 parts of semen raphani, 1 to 9 parts of radix ophiopogonis, 16 to 24 parts of yam, 7 to 13 parts of rhodiola rosea and 7 to 13 parts of fructus cannabis. The traditional Chinese medicine preparation for treating the constipation has the advantages that the traditional Chinese medicine preparation takes an effect within 3 days after being taken; the obvious improvement is achieved in one week; the constipation condition does not occur again within 2 weeks; the constipation can be thoroughly and radically cured after a patient persists in taking the traditional Chinese medicine preparation for 2 to 3 months.
Description
Technical field
The invention belongs to the technical field of Chinese medicine, be specifically related to a kind of Chinese medicine preparation for the treatment of constipation.
Background technology
Constipation is clinical common complicated symptom, mainly refers to that defecation frequency reduces, feces amount reduces, dry and hard, the defecation effort of feces etc.Its reason is complicated, how relevant with gastrointestinal function, kind of ingesting and custom, living habit, environmental factors, the mental status etc.The traditional Chinese medical science is thought, constipation is mainly caused by dryness-heat stagnating in the interior, depression and stagnation of QI, deficiency of body fluid and spleen-kidney vacuity cold.Constipation can affect the people of each age group, and women is more than male, old more than person between twenty and fifty.Because constipation sickness rate is high, the cause of disease is complicated, bring a lot of worries to patient, when constipation is serious, can quality of life be affected.
The sickness rate of chronic constipation more than 60 years old crowd is that 7.3%-20.39%, 18-70 year adult onset leads is 6.07%, and women is more than 4 times of male.The main clinical manifestation of chronic constipation is that feces is dry and hard, difficult defecation, and row not to the utmost sense or defecation frequency reduces.In chronic constipation, functional constipation accounts for 57.1%, functional constipation clinical point of slow-remove type, Treatment of Outlet Obstruction Type and mixed type three kinds, and the overwhelming majority is slow-remove type.Functional constipation refers to constipation more than 6 months occurs, and gets rid of the constipation of organic disease.Patient mostly generally is old people or is young woman.List is difficult to determine typing from the symptom of constipation patient, and cause reason mostly indefinite, different pattern of syndrome needs different targeted treatment schemes.Be easy to differentiate that patient is the constipation of which pattern of syndrome by technique of anorectal manometry and gastrointestinal transmission experiment.If in transmission experiment inspection, the mark that patient discharges for 72 hours is less than 80%, and technique of anorectal manometry defecation action noncontradictory campaign, can be diagnosed as chronic slow-transit constipation.Chronic slow-transit constipation is that colonic peristalsis function is poor, and forward direction promotes unable, and feces is advanced slowly at intestinal, and moisture is caused by long-time taken in excess.Patients with slow-transit constipation clinical manifestation many dry without awareness of defecation or defecation inability, constipation with dry stool or feces, skin is coarse, lusterless complexion etc.Be that deficiency of vital energy promotion is unable, intestinal deficiency of body fluid, feces driving power is not enough, caused by resistance increases.
Most employing Folium Sennae, Radix Et Rhizoma Rhei, phenolphthalein tablet, aloe capsule, MAREN RUNCHANG WAN etc. of existing treatment constipation, these are weak effect in treatment constipation, and only take stopgap measures, do not effect a permanent cure, long-term taking even can produce melanosis coli, drug dependence etc.
Summary of the invention
The present invention is that to solve in prior art the medicine late result for the treatment of constipation poor, and existing Instestinal motility medicine only provides Instestinal motility, though can increase Instestinal motility, constipation relieving, long-term taking can produce the problem of electrocardiogram Q-T interval prolongation and drug-resistant effect.The invention provides a kind of new medicine preparation for the treatment of constipation, not only can provide Instestinal motility, and can provide " moisture ".
The present invention is the technical scheme realizing the employing of its object:
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: Radix Astragali 7-13 part, Herba Cistanches 7-13 part, Semen Trichosanthis 7-13 part, Semen Raphani 12-18 part, Radix Ophiopogonis 1-9 part, Rhizoma Dioscoreae 16-24 part, Radix Rhodiolae 7-13 part, Fructus Cannabis 7-13 part.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: Radix Astragali 8-12 part, Herba Cistanches 8-12 part, Semen Trichosanthis 8-12 part, Semen Raphani 13-17 part, Radix Ophiopogonis 2-8 part, Rhizoma Dioscoreae 18-22 part, Radix Rhodiolae 8-11 part, Fructus Cannabis 8-12 part.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 10 parts, Herba Cistanches 10 parts, Semen Trichosanthis 10 parts, Semen Raphani 15 parts, Radix Ophiopogonis 5 parts, Rhizoma Dioscoreae 20 parts, Radix Rhodiolae 10 parts, Fructus Cannabis 10 parts.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 7 parts, Herba Cistanches 7 parts, Semen Trichosanthis 7 parts, Semen Raphani 12 parts, Radix Ophiopogonis 1 part, Rhizoma Dioscoreae 16 parts, Radix Rhodiolae 7 parts, Fructus Cannabis 7 parts.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 13 parts, Herba Cistanches 13 parts, Semen Trichosanthis 13 parts, Semen Raphani 18 parts, Radix Ophiopogonis 9 parts, Rhizoma Dioscoreae 24 parts, Radix Rhodiolae 13 parts, Fructus Cannabis 13 parts.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 8 parts, Herba Cistanches 8 parts, Semen Trichosanthis 8 parts, Semen Raphani 13 parts, Radix Ophiopogonis 2 parts, Rhizoma Dioscoreae 18 parts, Radix Rhodiolae 8 parts, Fructus Cannabis 8 parts.
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 12 parts, Herba Cistanches 12 parts, Semen Trichosanthis 12 parts, Semen Raphani 17 parts, Radix Ophiopogonis 8 parts, Rhizoma Dioscoreae 22 parts, Radix Rhodiolae 11 parts, Fructus Cannabis 11 parts.
The invention has the beneficial effects as follows: the Chinese medicine preparation for the treatment of constipation of the present invention, take effect taking within 3 days, have clear improvement within 1 week, within 2 weeks, no longer occur constipation situation, adhere to taking and thoroughly can eradicate constipation in 2-3 month.
In the present invention, this four Chinese medicine of the Radix Astragali, Rhizoma Dioscoreae, Radix Rhodiolae and Semen Raphani combines and can make obviously to increase in body rabbit intestinal tube tensity, wriggling amplitude increases, obvious impetus is had to intestinal motility, in conjunction with the electrodeless ion of the effective ingredient in Herba Cistanches and hydrophilic colloid class polysaccharide, the moistening of feces can be promoted and discharge, improve myenteron motion, strengthen Intestinal motility, significantly shorten the relieving constipation time and suppress moisture absorption in large intestine.Rhizoma Dioscoreae: " invigorating middle warmer, physical strength profiting, longue meat ", also has preventive and therapeutic action to insufficiency of the spleen, have dual regulation to isolated intestinal motility.Fructus Cannabis matter profit greasiness energy loosening bowel to relieve constipation, and have again the effect of nourishing tonify deficiency concurrently, it produces fatty acid meet alkaline intestinal juice in intestinal after, stimulates intestinal wall, wriggling is strengthened, thus reaches defecating feces excretion.
The present invention, when the side's of sending medication, both on the basis be familiar with constipation pathogenesis for the traditional Chinese medical science, while selected tonifying QI to produce body fluid medicine, also combines gastrointestinal transit and tests feature that the intestinal conduction function that finds slows down and help the logical stagnant rule of fortune to the rule for the treatment of has been enriched.Help fortune logical stagnant be the innovation of treat slow Constipation principle, this innovation is the innovation that Traditional Chinese medical theory combines with modern science, is that inventor's summary that studies for a long period of time obtains.Wherein, the spleen invigorating of Radix Astragali tonifying the lung is principal agent, and Radix Rhodiolae, Rhizoma Dioscoreae help Radix Astragali tonifying the lung gas, and strengthen Instestinal motility, power-assisted is sailed a boat as accessory drugs.Promote the production of body fluid Radix Ophiopogonis and have the meaning of supplementing fluid to relax the bowels, control body fluid dry few, constipation due to insufficiency dyschezia is also accessory drugs.Semen Trichosanthis loosening bowel to relieve constipation is adjuvant drug.The benefaction of Semen Raphani acrid in the mouth, walks between intestinal under priming, and fortune can be helped to lead to stagnant working as making medicine.The expectorant of the Semen Raphani therapeutic method to keep the adverse QI flowing downwards, assaults fortified position long-pending, heavy after treatment, Semen Raphani energy " therapeutic method to keep the adverse QI flowing downwards ", and enter lung meridian, namely the therapeutic method to keep the adverse QI flowing downwards helps the respectful of lung to fall, the lung and the large intestine being interior-exteriorly related, and respectful the falling of lung qi is then defecated freely.
Chinese medicine preparation of the present invention is a close set compound that can not be split, every Herba indigoferae Pseudotinctoriae all plays vital effect in the composition, every Herba indigoferae Pseudotinctoriae complements each other, not only play respective effect and also promote the performance of other drug effects and the suppression of side effect, this is the long-term result summed up, its respective consumption decides the drug effect of whole medicament, in this compositions, the consumption of the Radix Astragali is determined according to chronic slow-transit constipation basic pathogenesis, prolonged constipation increases the weight of to consume gas, make gas more empty, Radix Astragali QI invigorating is applied in we, the few weak effect of amount, measure many " void is not mended ", cause abdominal distention, in prescription screening process, through long-term creative research, screen, the optimal dose that just must appear at and proportioning.Yin-nourishing drug is cold and cool for Radix Ophiopogonis, and easily injure one's stomach gas, hinders digestion, and when consumption is few, take effect slow, cause anorexia when consumption is large, poor appetite, thick fur is greasy.Should mend and unsuitable high benefit slowly in conjunction with chronic slow-transit constipation basic pathogenesis.Herba Cistanches, can strengthen Intestinal motility, improves intestinal motive force, and amount hour is effective greatly not as amount, but when this consumption is large, causes few patients's abdominal part slightly uncomfortable because propulsive force is excessive, and we are through repeatedly verifying, Herba Cistanches 10 parts is optimal dose.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 10 parts, Herba Cistanches 10 parts, Semen Trichosanthis 10 parts, Semen Raphani 15 parts, Radix Ophiopogonis 5 parts, Rhizoma Dioscoreae 20 parts, Radix Rhodiolae 10 parts, Fructus Cannabis 10 parts.
Embodiment 2
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 7 parts, Herba Cistanches 7 parts, Semen Trichosanthis 7 parts, Semen Raphani 12 parts, Radix Ophiopogonis 1 part, Rhizoma Dioscoreae 16 parts, Radix Rhodiolae 7 parts, Fructus Cannabis 7 parts.
Embodiment 3
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 13 parts, Herba Cistanches 13 parts, Semen Trichosanthis 13 parts, Semen Raphani 18 parts, Radix Ophiopogonis 9 parts, Rhizoma Dioscoreae 24 parts, Radix Rhodiolae 13 parts, Fructus Cannabis 13 parts.
Embodiment 4
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 8 parts, Herba Cistanches 8 parts, Semen Trichosanthis 8 parts, Semen Raphani 13 parts, Radix Ophiopogonis 2 parts, Rhizoma Dioscoreae 18 parts, Radix Rhodiolae 8 parts, Fructus Cannabis 8 parts.
Embodiment 5
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 12 parts, Herba Cistanches 12 parts, Semen Trichosanthis 12 parts, Semen Raphani 17 parts, Radix Ophiopogonis 8 parts, Rhizoma Dioscoreae 22 parts, Radix Rhodiolae 11 parts, Fructus Cannabis 12 parts.
Embodiment 6
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 9 parts, Herba Cistanches 9 parts, Semen Trichosanthis 9 parts, Semen Raphani 14 parts, Radix Ophiopogonis 3 parts, Rhizoma Dioscoreae 17 parts, Radix Rhodiolae 9 parts, Fructus Cannabis 9 parts.
Embodiment 7
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 11 parts, Herba Cistanches 11 parts, Semen Trichosanthis 11 parts, Semen Raphani 16 parts, Radix Ophiopogonis 4 parts, Rhizoma Dioscoreae 19 parts, Radix Rhodiolae 12 parts, Fructus Cannabis 11 parts.
Embodiment 8
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 9.5 parts, Herba Cistanches 9.5 parts, Semen Trichosanthis 9.5 parts, Semen Raphani 14.5 parts, Radix Ophiopogonis 6 parts, Rhizoma Dioscoreae 21 parts, Radix Rhodiolae 9.5 parts, Fructus Cannabis 9.5 parts.
Embodiment 9
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 10.5 parts, Herba Cistanches 10.5 parts, Semen Trichosanthis 10.5 parts, Semen Raphani 15.5 parts, Radix Ophiopogonis 7 parts, Rhizoma Dioscoreae 23 parts, Radix Rhodiolae 10.5 parts, Fructus Cannabis 10.5 parts.
Embodiment 10
Treat a Chinese medicine preparation for constipation, in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 9.2 parts, Herba Cistanches 12.1 parts, Semen Trichosanthis 10.7 parts, Semen Raphani 17.3 parts, Radix Ophiopogonis 6.5 parts, Rhizoma Dioscoreae 21.1 parts, Radix Rhodiolae 12.7 parts, Fructus Cannabis 12.7 parts.
The concrete preparation method of Chinese medicine preparation of the present invention is: take each raw material in the ratio number of raw material, then each raw material is placed in high pressure traditional Chinese medicine extracting machine and decocts 0.8-1.5 hour, preferably 1 hour, and squeezing extracting juice, vacuum packaging forms.
By above-described embodiment and mosapride (carry out clinical trial, result of the test is as follows:
Note: the present invention is △ P < 0.01 (mosapride 5mg 3/ day, taking medicine before meal) compared with mosapride
Case one
Model, women, 51 years old, tells constipation with dry stool, is difficult to walk, and defecation is required great effort 4 years, and non-drug can not be gone, usually the medicine such as oral " aloe capsule, phenolphthalein tablet ", and help defecation, private prosecution, usually without obvious awareness of defecation, looks into electronics intestinal mirror: melanosis coli.Colonic transit is tested: 72h makes film, residual 12 pieces of mark.Diagnosis: chronic slow-transit constipation.Give the present invention oral, 150ml 2 times/day, decoction being taken warmly, take stool and defecation time two days later comparatively before to make moderate progress, colonic transit test shows in 72 hours that discharging mark number comparatively before makes moderate progress, about 1 week rear patient tells defecation effort symptom and is clearly better, and continue to take medicine 4 days, defecation once a day, the soft shaping of matter, defecation time is no more than 5min, and colonic transit test showed in 72 hours discharges mark number more than 90%, and the 1 week post dose that continues to take medicine reduces by half, use 4 weeks again, drug withdrawal, patients symptomatic is not recurred, and it is always normal to follow up a case by regular visits to stool after half a year.
Case two
Wang, women, 47 years old, tell defecation not smooth, firmly just, defecation was required great effort 2 years, and oral " MAREN RUNCHANG WAN " is in conjunction with medicines such as glycerin usually, helps defecation, and private prosecution, usually without obvious awareness of defecation, looks into electronics intestinal mirror: colon becomes black.Colonic transit is tested: 72h makes film, residual 11 pieces of mark.Diagnosis: chronic slow-transit constipation.Give the present invention oral, 100ml 2 times/day, decoction being taken warmly, take stool and defecation time two days later comparatively before to make moderate progress, colonic transit test shows in 72 hours that discharging mark number comparatively before makes moderate progress, after about 3 days patient tell defecation effort symptom be clearly better, continue to take medicine 2 days, defecation is once a day, the soft shaping of matter, defecation time is no more than 3min, and colonic transit test showed in 72 hours discharges mark number more than 89%, and the post dose on the 3rd that continues to take medicine reduces by half, use 1 week again, drug withdrawal, patients symptomatic is not recurred, and it is always normal to follow up a case by regular visits to stool after half a year.
Case three
Xu certain, male, 39 years old, tells awareness of defecation few, and just secondary also few, defecation is required great effort 3.5 years, and non-drug can not be gone, usually the medicine such as oral " intestinal motive force medicine, tegaserod ", and help defecation, private prosecution, usually without obvious awareness of defecation, looks into electronics intestinal mirror: melanosis coli.Colonic transit is tested: 72h makes film, residual 10 pieces of mark.Diagnosis: chronic slow-transit constipation.Give the present invention oral, 150ml 2 times/day, decoction being taken warmly, take stool and defecation time two days later comparatively before to make moderate progress, colonic transit test shows in 72 hours that discharging mark number comparatively before makes moderate progress, about 1 week rear patient tells defecation effort symptom and is clearly better, and continue to take medicine 3 days, defecation once a day, the soft shaping of matter, defecation time is no more than 4min, and colonic transit test showed in 72 hours discharges mark number more than 90%, and the post dose on the three that continues to take medicine reduces by half, use 3 weeks again, drug withdrawal, patients symptomatic is not recurred, and it is always normal to follow up a case by regular visits to stool after half a year.
Claims (7)
1. treat a Chinese medicine preparation for constipation, it is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: Radix Astragali 7-13 part, Herba Cistanches 7-13 part, Semen Trichosanthis 7-13 part, Semen Raphani 12-18 part, Radix Ophiopogonis 1-9 part, Rhizoma Dioscoreae 16-24 part, Radix Rhodiolae 7-13 part, Fructus Cannabis 7-13 part.
2. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, it is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: Radix Astragali 8-12 part, Herba Cistanches 8-12 part, Semen Trichosanthis 8-12 part, Semen Raphani 13-17 part, Radix Ophiopogonis 2-8 part, Rhizoma Dioscoreae 18-22 part, Radix Rhodiolae 8-11 part, Fructus Cannabis 8-12 part.
3. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 10 parts, Herba Cistanches 10 parts, Semen Trichosanthis 10 parts, Semen Raphani 15 parts, Radix Ophiopogonis 5 parts, Rhizoma Dioscoreae 20 parts, Radix Rhodiolae 10 parts, Fructus Cannabis 10 parts.
4. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 7 parts, Herba Cistanches 7 parts, Semen Trichosanthis 7 parts, Semen Raphani 12 parts, Radix Ophiopogonis 1 part, Rhizoma Dioscoreae 16 parts, Radix Rhodiolae 7 parts, Fructus Cannabis 7 parts.
5. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 13 parts, Herba Cistanches 13 parts, Semen Trichosanthis 13 parts, Semen Raphani 18 parts, Radix Ophiopogonis 9 parts, Rhizoma Dioscoreae 24 parts, Radix Rhodiolae 13 parts, Fructus Cannabis 13 parts.
6. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 8 parts, Herba Cistanches 8 parts, Semen Trichosanthis 8 parts, Semen Raphani 13 parts, Radix Ophiopogonis 2 parts, Rhizoma Dioscoreae 18 parts, Radix Rhodiolae 8 parts, Fructus Cannabis 8 parts.
7. a kind of Chinese medicine preparation for the treatment of constipation according to claim 1, is characterized in that: in this Chinese medicine preparation, the part by weight number of each raw material is: the Radix Astragali 12 parts, Herba Cistanches 12 parts, Semen Trichosanthis 12 parts, Semen Raphani 17 parts, Radix Ophiopogonis 8 parts, Rhizoma Dioscoreae 22 parts, Radix Rhodiolae 11 parts, Fructus Cannabis 11 parts.
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Cited By (2)
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| CN110507773A (en) * | 2019-09-26 | 2019-11-29 | 上海市静安区中医医院 | A kind of Chinese medicine composition that treating Parkinson's disease constipation and its application |
| CN115944669A (en) * | 2022-07-20 | 2023-04-11 | 中国人民解放军海军军医大学 | Traditional Chinese medicine composition for relieving constipation and preparation method and application thereof |
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| CN103989924A (en) * | 2014-05-24 | 2014-08-20 | 上海有美健康咨询中心 | Traditional Chinese medicine composition enema for treating senile constipation |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110507773A (en) * | 2019-09-26 | 2019-11-29 | 上海市静安区中医医院 | A kind of Chinese medicine composition that treating Parkinson's disease constipation and its application |
| CN115944669A (en) * | 2022-07-20 | 2023-04-11 | 中国人民解放军海军军医大学 | Traditional Chinese medicine composition for relieving constipation and preparation method and application thereof |
| CN115944669B (en) * | 2022-07-20 | 2024-01-30 | 中国人民解放军海军军医大学 | Traditional Chinese medicine composition for relieving constipation and preparation method and application thereof |
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