CN104922281A

CN104922281A - Traditional Chinese medicine composition of patch-type ointment for treating slow-transit constipation and preparation method thereof

Info

Publication number: CN104922281A
Application number: CN201410103168.5A
Authority: CN
Inventors: 刘春强; 张岚
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-20
Filing date: 2014-03-20
Publication date: 2015-09-23

Abstract

The invention relates to the drugs, and especially relates to a traditional Chinese medicine composition of a patch-type ointment for treating slow-transit constipation and a preparation method thereof. The traditional Chinese medicine composition is composed of 5 to 30 grams of raw rehmannia root, 10 to 30 grams of Chinese angelica, 20 to 60 grams of radix astragali, 10 to 30 grams of cistanche, 10 to 30 grams of bitter orange, 10 to 30 grams of rheum officinale, 10 to 30 grams of bighead atractylodes rhizome, and 2 to 15 grams of borneol, and is mainly used to treat slow-transit constipation. The raw materials are cheap and easily-available, and thus the comprehensive cost is low. The preparation technology of patch-type ointment is simple, and the patch-type ointment has the characteristics of direct application, definite curative effect, simple and convenient operation, little side or toxic effect, and no pain, and thus is beneficial for production and clinical application. If the patch-type ointment is used according to the treatment course, the symptom can be relieved within a week, and compared with similar drugs, the provided ointment has a wider development prospect.

Description

A kind ofly treat chronic slow-transit constipation Chinese prescription sticking ointment and preparation method thereof

Art

The invention belongs to medical art, relate to drug class, treat chronic slow-transit constipation Chinese prescription sticking ointment and preparation method thereof in particular to a kind of.

Background technology

Constipation refers to because large intestine conduction is not normal, causes constipation, defecation cycle stretch-out; Or the cycle is not long, but excrement matter is dry and hard, and it is difficult to discharge; Or excrement matter is not hard, though there is awareness of defecation, just and not smooth disease.It is symptom common clinically, has both been found in the process of various diseases, can occur separately again, and the people at any age may occur.Constipation is divided into by the difference according to clinical manifestation and auxiliary examination result: slow-remove type, Treatment of Outlet Obstruction Type, slow transmission Treatment of Outlet Obstruction Type and irritable bowel syndrome 4 type.Wherein the sickness rate of chronic slow-transit constipation is the highest, account for 45.5%, chronic slow-transit constipation is also known as slow transit constipation or atony of colon, it is the Gl transit dysfunction because a variety of causes causes, intestinal contents transmission delay and the constipation that causes, clinical manifestation is that times of defecation reduces, and awareness of defecation disappears, symptom such as companion's abdominal distention etc., has chronic, constitutional, the feature such as functional.This chronic disease affects the physical and mental health of patient for a long time, patient easily irritated exciting, feel depressed, easily cause obesity, anal fissure, the simultaneous phenomenons such as dyspepsia.

Chinese traditional treatment constipation has rich experience and advantage clinically, treating both the principal and secondary aspects of a disease, always by extensive patients is approved.Due to constipation need adhere to treatment, a lot of patient suffer from Chinese medicine for oral administration decoct miscellaneous, take difficulty and give up halfway, therefore Chinese drug preparation become stick ointment, facilitate Clinical practice and patient adhere to treatment.

Summary of the invention

Constipation Chinese prescription sticking ointment that the object of the present invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease and preparation method thereof.Technical scheme is as follows:

1. treat chronic slow-transit constipation Chinese prescription sticking ointment and preparation method thereof for one kind, it is characterized in that being made up of the Chinese medicine such as Radix Rehmanniae 5 ~ 30g, Radix Angelicae Sinensis 10 ~ 30g, the Radix Astragali 20 ~ 60g, Herba Cistanches 10 ~ 30g, Fructus Aurantii Immaturus 10 ~ 30g Radix Et Rhizoma Rhei 10 ~ 30g, the Rhizoma Atractylodis Macrocephalae 10 ~ 30g, Borneolum Syntheticum 2 ~ 15g.

2. treat the Chinese medicinal preparation method that chronic slow-transit constipation sticks ointment for one kind, step is as follows: take the raw material Chinese medicine Radix Rehmanniae 10g of weight described in claim 1, Radix Angelicae Sinensis 15g, Radix Astragali 30g, Herba Cistanches 20g, Fructus Aurantii Immaturus 20g, add water about 760ml, after decocting 30min, obtains 230ml decocting liquid.Second time decocts, and after add water 380ml, 30min, obtain decocting liquid 100ml, by the concentration of liquid medicine of 330ml to 50ml, concentrated solution is for subsequent use; Separately Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis Macrocephalae 20g, Borneolum Syntheticum 5g are beaten powder sieving for standby, add sodium benzoate 0.15g in concentrated solution, boil and be dissolved to 30ml, cooling, add Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, borneol powder stir, then add the starch that 3g dissolved and stir a little, obtain brownish black plaster.

3. saving grace of the present invention: reuse Radix Astragali invigorating the spleen and replenishing QI in prescription is monarch drug; The Radix Rehmanniae promotes the production of body fluid and moisturizes, Chinese Angelica blood replonishing loosening bowel to relieve constipation, and Rhizoma Atractylodis Macrocephalae spleen invigorating helps fortune, the intestine moistening of Herba Cistanches kidney tonifying, and four medicines share plays strengthening spleen, tonifying kidney, loosening bowel to relieve constipation altogether, effect of qi and blood tonifying, is ministerial drug altogether; Radix Et Rhizoma Rhei heat and toxic materials clearing away, relaxing the bowels with lubricant drugs softening the hard mass, cleansing the intestines and stomach, Fructus Aurantii Immaturus dispelling the stagnated QI removing food stagnancy, is adjuvant drug altogether; Borneolum Syntheticum have one's ideas straightened out disperse, in priming enters, for making medicine.All medicines share and play strengthening spleen, tonifying kidney altogether, the increasing liquid that nourishes blood, wide intestinal are regulated the flow of vital energy, the effect of relaxing the bowels with lubricant drugs relieving constipation.Have not yet to see clinical practice in the applicator of special for treating chronic slow-transit constipation, there is wider development prospect.Chinese medicine is specifically described as follows:

Radix Rehmanniae: sweet, bitter, cold; GUIXIN, liver, kidney channel; Clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; To join the army blood for warm febrile disease, hematemesis and epistaxis, has blood in stool, metrorrhagia, maculopapulae due to toxic heat, and calentura is thirsty, dryness of the intestine constipation.

Radix Angelicae Sinensis: sweet, pungent, bitter, tepor; Return liver, the heart, spleen channel; Enrich blood, invigorate blood circulation, regulating menstruation, pain relieving, intestine moistening; Weight, ulcer sores, injury from falling down after, metrorrhagia poly-for all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine constipation, bloody dysentery.The Radix Astragali: sweet, tepor; Return lung, spleen channel; Tonifying Qi and lifting yang, benefiting QI for strengthening the superficies, arresting sweating take off admittedly, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema, poison holding, evacuation of pus; , anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis weak for the deficiency of vital energy, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty are burst, burst for a long time do not hold back, blood deficiency and yellow complexion, interior-heat quench one's thirst.

Herba Cistanches: sweet, salty, temperature; Return kidney, large intestine channel; Kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation; For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.

Fructus Aurantii Immaturus: bitter, acrid, cold; Return spleen, stomach, large intestine channel; Dispelling the stagnated QI removing food stagnancy, reduce phlegm except painful abdominal mass; For weight, blocked-up chest, flatulence, gastroptosis, uterine prolapse, proctoptosis after stagnation of QI due to dyspepsia, gastral cavity abdomen feeling of fullness, stagnation of phlegm-damp, feeling of oppression and fullness in the chest and epigastrium, constipation, dysentery.

Radix Et Rhizoma Rhei: bitter, cold; Return spleen, stomach, large intestine, liver, pericardium channel; Heat and toxic materials clearing away, clearing away heat-fire, hemostasis, removing toxic substances, blood circulation promoting and blood stasis dispelling, clearly rush down damp and hot; For gastrointestinal retention, constipation, conjunctival congestion, pharyngalgia, gingival swelling and pain, pathopyretic ulcer, erysipelas, scald, all cards of blood stasis, jaundice, stranguria.

The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature; Return spleen, stomach warp; Air making-up and spleen enlivening, dampness diuretic, strengthening superficial resistance to stop perspiration, antiabortive; For anorexia and loose stool, distension and fullness in the abdomen, the soft Mental fatigue of limb, phlegm retention, edema, dysuria, spontaneous perspiration, frequent fetal movement.

Borneolum Syntheticum: pungent, bitter, is slightly cold; GUIXIN, spleen, lung meridian; To have one's ideas straightened out refreshment, clearing away heat to alleviate pain; Swell and ache for excess syndrome of stroke coma, conjunctival congestion and swelling pain, sore throat aphtha, skin infection.

Detailed description of the invention:

By embodiment below, the invention will be further described, but be not limited to embodiment.Embodiment step is as follows: take Radix Rehmanniae 10g, Radix Angelicae Sinensis 15g, Radix Astragali 30g, Herba Cistanches 20g, Fructus Aurantii Immaturus 20g, and add water about 760ml, after decocting 30min, obtains 230ml decocting liquid.Second time decocts, and after add water 380ml, 30min, obtain decocting liquid 100ml, by the concentration of liquid medicine of 330ml to 50ml, concentrated solution is for subsequent use; Separately Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis Macrocephalae 20g, Borneolum Syntheticum 5g are beaten powder sieving for standby, add sodium benzoate 0.15g in concentrated solution, boil and be dissolved to 30ml, cooling, add Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, borneol powder stir, then add the starch that 3g dissolved and stir a little, obtain brownish black plaster.Directly use during treatment be prepared into stick ointment.Every day one pastes, and applies ointment or plaster 6 hours at every turn, and continuous 10 days is a course for the treatment of, and 3 courses for the treatment of are advisable.

Claims

1. treat chronic slow-transit constipation Chinese prescription sticking ointment and preparation method thereof for one kind, it is characterized in that being made up of Radix Rehmanniae 5 ~ 30g, Radix Angelicae Sinensis 10 ~ 30g, the Radix Astragali 20 ~ 60g, Herba Cistanches 10 ~ 30g, Fructus Aurantii Immaturus 10 ~ 30g Radix Et Rhizoma Rhei 10 ~ 30g, the Rhizoma Atractylodis Macrocephalae 10 ~ 30g, Borneolum Syntheticum 2 ~ 15g Chinese medicine.

2. treat chronic slow-transit constipation Chinese prescription sticking ointment and preparation method thereof for one kind, it is characterized in that optimum weight is Radix Rehmanniae 10g, Radix Angelicae Sinensis 15g, Radix Astragali 30g, Herba Cistanches 20g, Fructus Aurantii Immaturus 20g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis Macrocephalae 20g, Borneolum Syntheticum 5g according to right 1.

3. according to its main effect of Chinese prescription of right 1 be treatment chronic slow-transit constipation, anal fissure, hemorrhoid etc.

4. be prepared into Chinese medicine application ointment according to the Chinese prescription of right 1, step is as follows: take the Radix Rehmanniae 10g of weight described in right 2, Radix Angelicae Sinensis 15g, Radix Astragali 30g, Herba Cistanches 20g, Fructus Aurantii Immaturus 20g, and add water about 760ml, after decocting 30min, obtains 230ml decocting liquid.Second time decocts, and after add water 380ml, 30min, obtain decocting liquid 100ml, by the concentration of liquid medicine of 330ml to 50ml, concentrated solution is for subsequent use; Separately Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis Macrocephalae 20g, Borneolum Syntheticum 5g are beaten powder sieving for standby, add sodium benzoate 0.15g in concentrated solution, boil and be dissolved to 30ml, cooling, add Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, borneol powder stir, then add the starch that 3g dissolved and stir a little, obtain brownish black ointment.