CN103751521A - Drug for treating habitual constipation - Google Patents

Drug for treating habitual constipation Download PDF

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CN103751521A
CN103751521A CN201410049595.XA CN201410049595A CN103751521A CN 103751521 A CN103751521 A CN 103751521A CN 201410049595 A CN201410049595 A CN 201410049595A CN 103751521 A CN103751521 A CN 103751521A
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radix
constipation
drug
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CN103751521B (en
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王怀方
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Shandong Provincial Hospital
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Abstract

The invention discloses a drug for treating habitual constipation. The drug is prepared from the following crude drugs by weight: radix ophiopogonis, roots of common peony, roots of three-nerved spicebush, Chinese angelica, mangnolia officinalis, pericarpium arecae, polygonum multiflorum, fructus aurantii, bighead atractylodes rhizome, herba cistanche, dried tangerine or orange peel, radix rehmanniae recen, roots of hairy asiabell, poria cocos, trichosanthes peel, astragalus membranaceus, fructus cannabis, rheum officinale and licorice roots. The drug provided by the invention treats constipation through regulating viscera functions of a human body, and takes effects of nourishing yin and blood, benefiting lung and tonifying spleen, tonifying Qi and activating blood and relaxing bowel as the principle to treat the disease from the root and increase humor to move the grounded ship, so as to achieve the purposes of detoxification and bowel relaxing.

Description

A kind of medicine for the treatment of habitual constipation
Technical field
The present invention relates to a kind of medicine for the treatment of constipation, be specially a kind of medicine for the treatment of habitual constipation.
Background technology
Constipation is that constipation is obstructed, and defecation frequency reduces or stool moist, and defecation time extends or wish is defecated and involved and abstruse not smooth a kind of disease.Constipation is temporary, also long-term, and we are also referred to as habitual constipation common prolonged constipation.Prolonged constipation can be accompanied abdominal distention, stomachache, and the symptoms such as stool band blood, easily cause insomnia and dreamful sleep, dysphoria, are off one's feed, the symptom such as pachylosis, easily bring out hemorrhoid, anal fissure, proctoptosis, prostate hyperplasia, even cause the diseases such as colon cancer, the heart, cerebrovascular.
The drug kinds for the treatment of constipation is at present various, but effect is all not satisfactory, and western medical treatment constipation, can only give cathartic relieving constipation, take the medicine that tool purging FU-organs rushes down lower function, but cathartic takes meeting for a long time, consume human righteousness, in addition, long-term dependence catharsis agent relieving constipation, while no longer taking suddenly, also can cause constipation; Also there is easily recurrence in the Chinese prescription of existing Chinese traditional treatment constipation, is difficult to the problems such as elimination mostly.
Summary of the invention
The present invention, on the basis of the mechanism of the morbidity of further investigation constipation, develops a kind of medicine for the treatment of habitual constipation, and the pure Chinese medicine of this medicine is made, and has no side effect, and can effectively treat habitual constipation.
The technical scheme that technical solution problem of the present invention is taked is: a kind of medicine for the treatment of habitual constipation, it is characterized in that, by the crude drug of following weight, made: Radix Ophiopogonis 8-12 gram, Radix Paeoniae Rubra 8-12 gram, Radix Linderae 8-12 gram, Radix Angelicae Sinensis 8-12 gram, Cortex Magnoliae Officinalis 8-12 gram, Pericarpium Arecae 8-12 gram, Radix Polygoni Multiflori 12-18 gram, Fructus Aurantii 12-18 gram, Rhizoma Atractylodis Macrocephalae 18-22 gram, Herba Cistanches 18-22 gram, Pericarpium Citri Reticulatae 18-22 gram, Radix Rehmanniae 18-22 gram, Radix Codonopsis 22-28 gram, Poria 28-32 gram, Pericarpium Trichosanthis 28-32 gram, Radix Astragali 28-32 gram, Fructus Cannabis 28-32 gram, Radix Et Rhizoma Rhei 5-8 gram and Radix Glycyrrhizae 3-8 gram.
Optimum ratio: 10 grams of Radix Ophiopogonis, 10 grams of Radix Paeoniae Rubra, 10 grams of the Radixs Linderae, 10 grams of Radix Angelicae Sinensis, 10 grams of Cortex Magnoliae Officinalis, 10 grams of Pericarpium Arecae, 15 grams of Radix Polygoni Multiflori, 15 grams of Fructus Aurantiis, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Herba Cistanches, 20 grams of Pericarpium Citri Reticulataes, 20 grams of Radix Rehmanniae, 25 grams of Radix Codonopsis, 30 grams, Poria, 30 grams of Pericarpium Trichosanthiss, 30 grams of the Radixs Astragali, 30 grams of Fructus Cannabiss, 6 grams, 6 grams of Radix Et Rhizoma Rhei and Radix Glycyrrhizae.
Make and using method: decocting boils, sooner or later take at twice.It within 15 days, is a course for the treatment of.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , mass in the abdomen stomachache, injury from falling down, carbuncle skin infection.
The Radix Linderae: acrid in the mouth, temperature, nontoxic.Enter spleen, lung, kidney, urinary bladder channel.Pleasant, dissipating depression of QI, cold expelling, pain relieving.Control QI rising in reverse order chest and abdomen swelling and pain, dyspepsia does not disappear, and food is told in regurgitation, colic of cold type, beriberi, frequent micturition.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Cortex Magnoliae Officinalis: toil, temperature.Enter spleen, stomach, large intestine channel.Have that removing dampness intestinal stasis relieving, circulation of qi promoting are relievingd asthma, wind dispelling analgesic effect.
Pericarpium Arecae: therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, eliminating the pathogens from the lung in tune, easing stomach-QI, row water.Control gastral cavity abdomen painful abdominal mass swollen, logical intestine and small intestine, spleen benefiting and stimulating the appetite, dampness removing chases after wind, wide intestinal detumescence.
Radix Polygoni Multiflori: bitter, sweet, puckery, tepor.Return liver, the heart, kidney channel.Function with cure mainly: removing toxic substances, eliminating carbuncle, preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.For carbuncle sore scrofula, rubella pruritus, chronic malaria body void, dryness of the intestine constipation.
Fructus Aurantii: toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
The Rhizoma Atractylodis Macrocephalae: spleen reinforcing, stomach reinforcing, dampness, and in.Control deficient QI of the spleen and stomach, anorexia asthenia weak breath, deficiency-distension, edema, arthralgia chiefly caused by damp pathogen, spontaneous perspiration.
Herba Cistanches: the kidney invigorating, benefit essence, moisturizes laxation.Control impotence in male, infertilitas feminis, leukorrhagia, metrorrhagia, chills and pain of the waist and kness, blood depletion constipation.
Pericarpium Citri Reticulatae: warm in nature, bitter in the mouth, pungent.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough ant phlegm.
Radix Rehmanniae: clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, for the refrigerant product that moisten, is good at nourishing YIN and clearing away heat removing heat from blood.Effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.
Radix Codonopsis: sweet, flat.Start with, meridian of Foot-TAI YIN edema caused by disorder of QI.Invigorating the spleen and replenishing QI, promotes the production of body fluid, and nourishes blood.For the empty asthenia of body of deficiency of QI in middle-JIAO, weakness of the spleen and stomach, deficiency of both QI and blood, controls fatigue and lack of strength, lung qi virtual loss.Control lack of appetite, thirsty, chronic diarrhea, proctoptosis.And the two shallow complexions of losing of QI and blood, dizzy cardiopalmus etc.
Poria: sweet light, flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.
Pericarpium Trichosanthis: sweet, cold.Attach to the lung and stomach meridians.Function with cure mainly: removing heat-phlegm, promoting the circulation of QI the chest stuffiness relieving.For phlegm-heat cough, hypochondriac pain uncomfortable in chest.
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Fructus Cannabis: moisturize, laxation, treating stranguria, invigorate blood circulation.Control dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, scabies.
Radix Et Rhizoma Rhei: bitter in the mouth, cold.Enter stomach, large intestine, Liver Channel.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.The poison that purges heat, removing mass is stagnant, clots absorbing blood.Control excess-heat constipation, delirium is sent out holder, food stagnation feeling of fullness, dysentery is from the beginning of, tenesmus, stasis of blood menolipsis Bi , lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, also urinates, carbuncle and ulcer toxic swelling, furuncle, burn.
Radix Glycyrrhizae: and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Process with controlling weakness of the spleen and stomach lack of appetite, cardiopalmus, overstrain heating.
The traditional Chinese medical science thinks, constipation is mainly caused by dryness-heat stagnating in the interior, depression and stagnation of QI, deficiency of body fluid and spleen-kidney vacuity cold.If tend to injure healthy energy under rushing down with purging FU-organs simply in clinical treatment, cause most of patients drug dependence to cause vicious cycle.Drug therapy constipation of the present invention is started with from the function of conditioning human body, take nourishing YIN and supplementing blood, lung benefiting spleen invigorating, inrigorating qi and promoting blood circulation, loosening bowel to relieve constipation as principle, with treatment must aim at the pathogenesis of disease, increases liquid and sails a boat, and reaches the object of toxin expelling relieving constipation.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data
Select habitual constipation case 90 people, wherein male 32 examples, female's 58 examples, at 9~70 years old age, this group patient all has difficult defecation, excrement matter is hard, defecation is felt not to the utmost, the infrequent defecation time is long.
2, Therapeutic Method
Take medicine of the present invention, decocting boils, and sooner or later takes at twice.Serveing on 15 days is a course for the treatment of.Generally take medicine 1~2 course for the treatment of, period in a medicine is avoided and is taken pungent scorching product, gives dietetic regulation simultaneously, forms the custom of timing stool, to consolidate curative effect.
3, efficacy assessment standard:
1) recovery from illness: symptom disappears substantially, and defecation is unobstructed, stool every day 1 time, just matter is shaping soft stool or mushy stool, and keeps continuously more than 2 weeks.
2) effective: defecation frequency is significantly increased, more than 4 times, just soft discharge is smooth weekly, and other symptom is obviously improved, but occurs again difficult defecation in 2 weeks.
3) effective: defecation frequency increases weekly more than 1 time on original basis, and other symptom is improved, but still has difficult defecation.
4) invalid: before and after constipation situation and simultaneous phenomenon treatment, nothing changes.
4, therapeutic outcome:
This group of result recovery from illness 79 examples, effective 9 examples, effective 2 examples.Cure rate: 87.8%; Obvious effective rate: 97.8%, effective percentage: 100%.
The present invention is by after above drug regimen, and drug effect has synergism, plays the effect of nourishing YIN and supplementing blood, lung benefiting spleen invigorating, inrigorating qi and promoting blood circulation, loosening bowel to relieve constipation, and in order to treat various habitual constipations, determined curative effect, can life-time service, and can not form dependence.
Two, model case
Case 1, grandson so-and-so, female, 54 years old.Suffer from chronic constipation more than 5 years, stool time is 1-2 time weekly, and feces is hard, and balling bulk.Often need take that rush down after leaf can relieving constipation, frequent diarrhoea again when just logical, drug withdrawal stool is obstructed, takes second day stool of we normal, after two courses for the treatment of of taking medicine, but again without constipation, fully recovers.
Case 2, in so-and-so, man, 71 years old.Constipation for many years, is defecated 4-6 days once, needs decoction being taken at a draught TONGBIAN LING, uses the medicine ability defecations such as glycerin before each defecation, more than each defecation all needs half an hour, with a face streaming with sweatly tired, painful abnormal.Take after the course for the treatment of of Drug therapy of the present invention, stool is normal.Consolidate the recovery from illness course for the treatment of.Effect of follow-up visit by telephone, so far not recurrence.
Case 3, Zhang, female 43 years old.Patient suffers from the existing 7-8 of chronic constipation, and patient often has awareness of defecation, but row not out, can discharge on a small quantity sometimes sometimes, and defecation not to the utmost.After need taking cathartic, can lead to, drug withdrawal stool is obstructed again.Patient took after two courses for the treatment of of medicine of the present invention, and symptom is obviously good just to be turned.Consolidate a course for the treatment of, stool is normal.Effect of follow-up visit by telephone, so far not recurrence.
The specific embodiment
Embodiment 1
Proportioning: 10 grams of Radix Ophiopogonis, 10 grams of Radix Paeoniae Rubra, 10 grams of the Radixs Linderae, 10 grams of Radix Angelicae Sinensis, 10 grams of Cortex Magnoliae Officinalis, 10 grams of Pericarpium Arecae, 15 grams of Radix Polygoni Multiflori, 15 grams of Fructus Aurantiis, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Herba Cistanches, 20 grams of Pericarpium Citri Reticulataes, 20 grams of Radix Rehmanniae, 25 grams of Radix Codonopsis, 30 grams, Poria, 30 grams of Pericarpium Trichosanthiss, 30 grams of the Radixs Astragali, 30 grams of Fructus Cannabiss, 6 grams of Radix Et Rhizoma Rhei, 6 grams, Radix Glycyrrhizae.
Make and using method: decocting boils, sooner or later take at twice.It within 15 days, is a course for the treatment of.
Embodiment 2
Proportioning: 12 grams of Radix Ophiopogonis, 12 grams of Radix Paeoniae Rubra, 12 grams of the Radixs Linderae, 12 grams of Radix Angelicae Sinensis, 12 grams of Cortex Magnoliae Officinalis, 12 grams of Pericarpium Arecae, 18 grams of Radix Polygoni Multiflori, 18 grams of Fructus Aurantiis, 22 grams of the Rhizoma Atractylodis Macrocephalaes, 22 grams of Herba Cistanches, 22 grams of Pericarpium Citri Reticulataes, 22 grams of Radix Rehmanniae, 28 grams of Radix Codonopsis, 32 grams, Poria, 32 grams of Pericarpium Trichosanthiss, 32 grams of the Radixs Astragali, 32 grams of Fructus Cannabiss, 8 grams, 8 grams of Radix Et Rhizoma Rhei and Radix Glycyrrhizae.
Make and using method: with embodiment 1.
Embodiment 3
Proportioning: 8 grams of Radix Ophiopogonis, 8 grams of Radix Paeoniae Rubra, 8 grams of the Radixs Linderae, 8 grams of Radix Angelicae Sinensis, 8 grams of Cortex Magnoliae Officinalis, 8 grams of Pericarpium Arecae, 12 grams of Radix Polygoni Multiflori, 12 grams of Fructus Aurantiis, 18 grams of the Rhizoma Atractylodis Macrocephalaes, 18 grams of Herba Cistanches, 18 grams of Pericarpium Citri Reticulataes, 18 grams of Radix Rehmanniae, 22 grams of Radix Codonopsis, 28 grams, Poria, 28 grams of Pericarpium Trichosanthiss, 28 grams of the Radixs Astragali, 28 grams of Fructus Cannabiss, 3 grams, 5 grams of Radix Et Rhizoma Rhei and Radix Glycyrrhizae.
Make and using method: with embodiment 1.

Claims (2)

1. a medicine for the treatment of habitual constipation, is characterized in that, by the crude drug of following weight, is made: Radix Ophiopogonis 8-12 gram, Radix Paeoniae Rubra 8-12 gram, Radix Linderae 8-12 gram, Radix Angelicae Sinensis 8-12 gram, Cortex Magnoliae Officinalis 8-12 gram, Pericarpium Arecae 8-12 gram, Radix Polygoni Multiflori 12-18 gram, Fructus Aurantii 12-18 gram, Rhizoma Atractylodis Macrocephalae 18-22 gram, Herba Cistanches 18-22 gram, Pericarpium Citri Reticulatae 18-22 gram, Radix Rehmanniae 18-22 gram, Radix Codonopsis 22-28 gram, Poria 28-32 gram, Pericarpium Trichosanthis 28-32 gram, Radix Astragali 28-32 gram, Fructus Cannabis 28-32 gram, Radix Et Rhizoma Rhei 5-8 gram and Radix Glycyrrhizae 3-8 gram.
2. a kind of medicine for the treatment of habitual constipation as claimed in claim 1, is characterized in that, by the crude drug of following weight, is made: 10 grams of Radix Ophiopogonis, 10 grams of Radix Paeoniae Rubra, 10 grams of the Radixs Linderae, 10 grams of Radix Angelicae Sinensis, 10 grams of Cortex Magnoliae Officinalis, 10 grams of Pericarpium Arecae, 15 grams of Radix Polygoni Multiflori, 15 grams of Fructus Aurantiis, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Herba Cistanches, 20 grams of Pericarpium Citri Reticulataes, 20 grams of Radix Rehmanniae, 25 grams of Radix Codonopsis, 30 grams, Poria, 30 grams of Pericarpium Trichosanthiss, 30 grams of the Radixs Astragali, 30 grams of Fructus Cannabiss, 6 grams, 6 grams of Radix Et Rhizoma Rhei and Radix Glycyrrhizae.
CN201410049595.XA 2014-02-13 2014-02-13 A kind of medicine for the treatment of habitual constipation Expired - Fee Related CN103751521B (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104042766A (en) * 2014-06-26 2014-09-17 夏征梅 Traditional Chinese medicinal composition for treating habitual constipation
CN104274553A (en) * 2014-10-27 2015-01-14 杨伟东 Traditional Chinese medicine with effect of relaxing bowels
CN104587125A (en) * 2015-01-04 2015-05-06 四川金堂海纳生物医药技术研究所 Orally taken medicine for treating qi-blood deficiency type constipation and preparation method thereof
CN104958746A (en) * 2015-08-01 2015-10-07 朱克兰 Foot bath composition for treating constipation and preparation method thereof
CN105687695A (en) * 2016-01-30 2016-06-22 毛毛 External application medicine for treating constipation caused by chemotherapy and preparation method thereof
CN106309907A (en) * 2016-11-11 2017-01-11 东莞市百替生物科技有限公司 Chinese herb preparation for treating habitual constipation and preparation method
CN108324861A (en) * 2018-05-17 2018-07-27 重庆跃龙生物制药有限公司 Has effects that Chinese medicine composition to replenish qi to invigorate the spleen and the preparation method and application thereof
CN109985158A (en) * 2017-12-30 2019-07-09 程艳青 A kind of Chinese medicine that treating habitual constipation and production method
CN114306507A (en) * 2022-01-04 2022-04-12 河南仲华国医馆有限公司 Composition for treating infantile habitual constipation and preparation method and application thereof

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CN101181508A (en) * 2007-11-15 2008-05-21 王玉鑫 Chinese medicine prescription orally taken for curing constipation

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104042766A (en) * 2014-06-26 2014-09-17 夏征梅 Traditional Chinese medicinal composition for treating habitual constipation
CN104274553A (en) * 2014-10-27 2015-01-14 杨伟东 Traditional Chinese medicine with effect of relaxing bowels
CN104587125A (en) * 2015-01-04 2015-05-06 四川金堂海纳生物医药技术研究所 Orally taken medicine for treating qi-blood deficiency type constipation and preparation method thereof
CN104958746A (en) * 2015-08-01 2015-10-07 朱克兰 Foot bath composition for treating constipation and preparation method thereof
CN105687695A (en) * 2016-01-30 2016-06-22 毛毛 External application medicine for treating constipation caused by chemotherapy and preparation method thereof
CN106309907A (en) * 2016-11-11 2017-01-11 东莞市百替生物科技有限公司 Chinese herb preparation for treating habitual constipation and preparation method
CN109985158A (en) * 2017-12-30 2019-07-09 程艳青 A kind of Chinese medicine that treating habitual constipation and production method
CN108324861A (en) * 2018-05-17 2018-07-27 重庆跃龙生物制药有限公司 Has effects that Chinese medicine composition to replenish qi to invigorate the spleen and the preparation method and application thereof
CN114306507A (en) * 2022-01-04 2022-04-12 河南仲华国医馆有限公司 Composition for treating infantile habitual constipation and preparation method and application thereof

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