CN104800634A - Medicine for treating hypertension and preparation method thereof - Google Patents

Medicine for treating hypertension and preparation method thereof Download PDF

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Publication number
CN104800634A
CN104800634A CN201510203037.9A CN201510203037A CN104800634A CN 104800634 A CN104800634 A CN 104800634A CN 201510203037 A CN201510203037 A CN 201510203037A CN 104800634 A CN104800634 A CN 104800634A
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radix
rhizoma
fructus
medicine
mori
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信红雁
魏荣
李昂
李文飞
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SHANDONG PROVINCIAL CHEST HOSPITAL
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SHANDONG PROVINCIAL CHEST HOSPITAL
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Abstract

The invention discloses a medicine for treating hypertension and a preparation method thereof and belongs to the technical field of traditional Chinese medicines. The medicine is prepared from the following traditional Chinese medicines: corn stigma, lotus leaf, gastrodia elata, semen cassia, peanut shell, herba siegesbeckiae, cucumber sets, selfheal, combined spicebush root, black mulberry, garlic, bambusae caulis im taeniam, prepared rehmannia root, Chinese yam, bretschneider pear pericarp, jasmine, lotus plumule, scutellaria baicalensis, tribulus terrestris, chrysanthemum, uncaria, antelope's horn, radix gentianae, hawksbill, pinellia ternate, pericarpium citri reticulatae, poria cocos, rhizoma atractylodis, mangnolia officinalis, the root bark of white mulberry, the root of fangfeng, astragalus membranaceus, ginseng, angelica sinensis, radix paeoniae alba, donkey-hide gelatin, polygonum multiflorum, caulis spatholobi, the root of kudzu vine, ligusticum wallichii, corydalis tuber, fructus viticis and liquorice. After the traditional Chinese medicines are combined, the efficacies have the synergistic effect, so that the antihypertensive efficacy is remarkable; in addition, the pure natural Chinese herbal medicines are adopted, so that toxic or side effect is avoided.

Description

One treats hypertensive medicine and preparation method thereof
Technical field
The present invention relates to one and treat hypertensive medicine and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Hypertension is common clinical, frequently-occurring disease, and its prevalence is in the trend risen gradually.Hypertension is a kind of disease that in mankind's cardiovascular and cerebrovascular disease, sickness rate is the highest.In China, nearly 100,000,000 people suffer from hypertension at present.Because hypertension is the main cause causing the cardiovascular and cerebrovascular disease such as apoplexy, coronary heart disease, acute myocardial infarction, threaten very large to human health, therefore, its control is the emphasis of clinical position always.
Hyperpietic generally adopts treatment with western, takes medicine 1. diuretic.2. beta-blocker.3. calcium channel blocker.4. angiotensin converting enzyme inhibitor.5. angiotensin-ii receptor blocker.When clinical practice uses, patient's cardiovascular risk factors situation, target organ damage, Complication, efficacy of antihypertensive treatment, untoward reaction etc., all can affect the selection of depressor.But western medical treatment has a lot of unsatisfactory part 1, side effect large: some medicine can affect the metabolism of blood pressure and blood lipoid, and some medicine long-term taking can affect the sexual function of patient.2, in pressure reduction, unstable blood pressure is fixed: particularly early stage or senile hypertension, very responsive to Western medicine depressor, a medication blood pressure may fall too low, and even postural hypotension occurs, and reduce dosage or number of times, blood pressure may raise again very soon.
Summary of the invention
The object of the present invention is to provide one to treat hypertensive medicine and preparation method thereof, all select natural Chinese medicinal herb, effectively can treat hypertension.
The technical scheme that technical solution problem of the present invention is taked is:
One treats hypertensive medicine, it is characterized in that, be made up of the Chinese medicine of following weight portion: Stigma Maydis 15-25, Folium Nelumbinis 15-25, Rhizoma Gastrodiae 15-25, Semen Cassiae 15-25, Pericarppium arachidis hypogaeae 15-25, Herba Siegesbeckiae 15-25, seedling of Fructus Cucumidis sativi 15-25, Spica Prunellae 15-25, radix linderae 15-25, black Fructus Mori 15-25, Bulbus Allii 15-25, Caulis Bambusae In Taenia 10-20, Radix Rehmanniae Preparata 10-20, Rhizoma Dioscoreae 10-20, Pericarpium Pyri 10-20, Fructus Gardeniae 10-20, embryo nelumbinis 10-20, Radix Scutellariae 5-20, Fructus Atriplicis Sibiricae 5-20, Flos Chrysanthemi 5-20, Ramulus Uncariae Cum Uncis 5-20, Cornu Saigae Tataricae 5-20, Radix Gentianae 5-20, Carapax Eretmochelydis 5-20, Rhizoma Pinelliae 5-15, Pericarpium Citri Reticulatae 5-15, Poria 5-15, Rhizoma Atractylodis 5-15, Cortex Magnoliae Officinalis 5-15, Cortex Mori 5-15, Radix Saposhnikoviae 5-15, Radix Astragali 5-15, Radix Ginseng 5-15, Radix Angelicae Sinensis 5-15, Radix Paeoniae Alba 5-10, Colla Corii Asini 5-10, Radix Polygoni Multiflori 5-10, Caulis Spatholobi 5-10, Radix Puerariae 5-10, Rhizoma Chuanxiong 5-10, Rhizoma Corydalis 5-10, Fructus Viticis 5-10, Radix Glycyrrhizae 5-10.
Further, be made up of the Chinese medicine of following weight portion:
Stigma Maydis 15, Folium Nelumbinis 15, Rhizoma Gastrodiae 15, Semen Cassiae 15, Pericarppium arachidis hypogaeae 15, Herba Siegesbeckiae 15, seedling of Fructus Cucumidis sativi 15, Spica Prunellae 15, radix linderae 15, black Fructus Mori 15, Bulbus Allii 15, Caulis Bambusae In Taenia 10, Radix Rehmanniae Preparata 10, Rhizoma Dioscoreae 10, Pericarpium Pyri 10, Fructus Gardeniae 10, embryo nelumbinis 10, Radix Scutellariae 5, Fructus Atriplicis Sibiricae 5, Flos Chrysanthemi 5, Ramulus Uncariae Cum Uncis 5, Cornu Saigae Tataricae 5, Radix Gentianae 5, Carapax Eretmochelydis 5, the Rhizoma Pinelliae 5, Pericarpium Citri Reticulatae 5, Poria 5, Rhizoma Atractylodis 5, Cortex Magnoliae Officinalis 5, Cortex Mori 5, Radix Saposhnikoviae 5, the Radix Astragali 5, Radix Ginseng 5, Radix Angelicae Sinensis 5, the Radix Paeoniae Alba 5, Colla Corii Asini 5, Radix Polygoni Multiflori 5, Caulis Spatholobi 5, Radix Puerariae 5, Rhizoma Chuanxiong 5, Rhizoma Corydalis 5, Fructus Viticis 5, Radix Glycyrrhizae 5.
Further, be made up of the Chinese medicine of following weight portion:
Stigma Maydis 25, Folium Nelumbinis 25, Rhizoma Gastrodiae 25, Semen Cassiae 25, Pericarppium arachidis hypogaeae 25, Herba Siegesbeckiae 25, seedling of Fructus Cucumidis sativi 25, Spica Prunellae 25, radix linderae 25, black Fructus Mori 25, Bulbus Allii 25, Caulis Bambusae In Taenia 20, Radix Rehmanniae Preparata 20, Rhizoma Dioscoreae 20, Pericarpium Pyri 20, Fructus Gardeniae 20, embryo nelumbinis 20, Radix Scutellariae 20, Fructus Atriplicis Sibiricae 20, Flos Chrysanthemi 20, Ramulus Uncariae Cum Uncis 20, Cornu Saigae Tataricae 20, Radix Gentianae 20, Carapax Eretmochelydis 20, the Rhizoma Pinelliae 15, Pericarpium Citri Reticulatae 15, Poria 15, Rhizoma Atractylodis 15, Cortex Magnoliae Officinalis 15, Cortex Mori 15, Radix Saposhnikoviae 15, the Radix Astragali 15, Radix Ginseng 15, Radix Angelicae Sinensis 15, the Radix Paeoniae Alba 10, Colla Corii Asini 10, Radix Polygoni Multiflori 10, Caulis Spatholobi 10, Radix Puerariae 10, Rhizoma Chuanxiong 10, Rhizoma Corydalis 10, Fructus Viticis 10, Radix Glycyrrhizae 10.
Further, be made up of the Chinese medicine of following weight portion:
Stigma Maydis 20, Folium Nelumbinis 20, Rhizoma Gastrodiae 20, Semen Cassiae 20, Pericarppium arachidis hypogaeae 20, Herba Siegesbeckiae 20, seedling of Fructus Cucumidis sativi 20, Spica Prunellae 20, radix linderae 20, black Fructus Mori 20, Bulbus Allii 20, Caulis Bambusae In Taenia 15, Radix Rehmanniae Preparata 15, Rhizoma Dioscoreae 15, Pericarpium Pyri 15, Fructus Gardeniae 15, embryo nelumbinis 15, Radix Scutellariae 10, Fructus Atriplicis Sibiricae 10, Flos Chrysanthemi 10, Ramulus Uncariae Cum Uncis 10, Cornu Saigae Tataricae 10, Radix Gentianae 10, Carapax Eretmochelydis 10, the Rhizoma Pinelliae 10, Pericarpium Citri Reticulatae 10, Poria 10, Rhizoma Atractylodis 10, Cortex Magnoliae Officinalis 10, Cortex Mori 10, Radix Saposhnikoviae 10, the Radix Astragali 10, Radix Ginseng 10, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 8, Colla Corii Asini 8, Radix Polygoni Multiflori 8, Caulis Spatholobi 8, Radix Puerariae 8, Rhizoma Chuanxiong 8, Rhizoma Corydalis 8, Fructus Viticis 8, Radix Glycyrrhizae 8.
Present invention also offers a kind of preparation method for the treatment of hypertensive medicine, it is characterized in that, comprise the following steps:
1. raw material is taken according to the above-mentioned weight portion stated;
2. by step 1. in the raw material that takes add three times of water soakings 2 hours, decocting in water 30 minutes, pours out medicinal liquid; Add decocting in water again 30 minutes, pour out medicinal liquid; Twice medicinal liquid amalgamation rises, and cools completely, and obtains the hypertensive medicine for the treatment of of the present invention.
Instructions of taking: respectively at half an hour before breakfast, takes for after supper two hours.Serveing on 15 days is a course for the treatment of.
Pharmacological action:
Stigma Maydis: sweet, light is flat.Return bladder, liver, gallbladder meridian.Function cures mainly: inducing diuresis to remove edema, suppressing the hyperactive liver function of gallbladder promoting.For acute and chronic nephritis, edema, acute hepatitis, chronic hepatitis, hypertension, diabetes, chronic sinusitis, lithangiuria, Biliary Calculi, the disease such as dysuria, damp and hot jaundice.And can habitual abortion be prevented.
Folium Nelumbinis: nature and flavor are bitter is flat.Return liver, spleen, stomach warp.Function cures mainly: clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.For multiple hemorrhage and puerperal blood faints.
Rhizoma Gastrodiae: acrid in the mouth, temperature.Enter Liver Channel.Endogenous wind stopping, arresting convulsion. control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia.
Semen Cassiae: bitter sweet, cool.Enter liver, kidney channel.Have liver heat removing, improving eyesight, dispel the wind, effect of relieving constipation.Control the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.
Pericarppium arachidis hypogaeae: nature and flavor are light, puckery is flat.Function cures mainly: astringing lung-QI and relieving cough.For chronic cough asthma, cough with blood-flecked phlegm.
Herba Siegesbeckiae: nature and flavor are pungent, bitter, cold.Return liver, kidney channel.Function cures mainly: wind-damp dispelling, sharp joint, removing toxic substances.For rheumatic arthralgia, muscles and bones is unable, soreness of the waist and knees, quadriplegia, hemiplegia, rubella eczema.
Seedling of Fructus Cucumidis sativi: nature and flavor are bitter; Cool in nature, GUIXIN; Lung.Function cures mainly: heat clearing away; Reduce phlegm; Dampness removing; Removing toxic substances.Main phlegm-heat cough; Epilepsy; Damp-heat dysentery; Multiple abscess caused by damp-phlegm; Sore and toxic; Hypertension.
Spica Prunellae: nature and flavor are pungent, bitter, cold.Return liver, gallbladder meridian.Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Radix linderae: nature and flavor are pungent, temperature.Return lung, spleen, kidney, urinary bladder channel.Function cures mainly: pleasant pain relieving, warming kidney for dispelling cold.For chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
Black Fructus Mori: the acid of Fructus Mori sweet in the mouth, cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving.There is YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, the effects such as intestine moistening is dry,
Bulbus Allii: nature and flavor are pungent, temperature.Function cures mainly: stomach invigorating, dysentery relieving, cough-relieving, sterilization, anthelmintic.Prevention influenza, epidemic cerebrospinal meningitis.Control pulmonary tuberculosis, pertussis, inappetence, dyspepsia, bacillary dysentery, amebic dysentery, enteritis, enterobiasis, ancylostomiasis; Trichomonas vaginitis is controlled in external, acute appendicitis.
Caulis Bambusae In Taenia: nature and flavor are sweet, is slightly cold.Attach to the lung and stomach meridians.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, and eye is lost in palpitation with fear, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.
Radix Rehmanniae Preparata: sweet, tepor.Gui Jing: return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Function cures mainly: spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
Pericarpium Pyri: nature and flavor are sweet; Puckery; Cool; Nontoxic, Gui Jing: lung; The heart; Kidney; Large intestine channel, function cures mainly: clearing away heart-fire and moistening the lung; Pathogenic fire reducing promotes the production of body fluid, and separates sore.Main summer-heat excessive thirst; Xeropulmonary cough; Spit blood; Dysentery; ; Scabies; Carbuncle on the back; Furuncle
Fructus Gardeniae: bitter, cold.Enter the heart, liver, lung, stomach warp.Heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.
Embryo nelumbinis: cold in nature, bitter in the mouth, nontoxic, the effects such as having clears away heart-fire reduces phlegm and internal heat, arresting seminal emission, hemostasis, cough-relieving, can treat heart failure, shock, sexual impotence, vexed, thirsty, haematemesis, seminal emission, conjunctival congestion, the disease such as swell and ache.There is blood sugar reducing function.
Radix Scutellariae: bitter, cold.Enter the heart, lung, gallbladder, large intestine channel.Removing the relative excess fire, remuval of damp and hot, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leak, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.
Fructus Atriplicis Sibiricae: temperature. bitter in the mouth. nontoxic. main stagnant blood. broken crux is gathered. sore throat. breast is difficult. take longue meat for a long time. improving eyesight is made light of one's life by commiting suicide.
Flos Chrysanthemi: sweet, bitter, is slightly cold.Return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.
Ramulus Uncariae Cum Uncis: sweet is cool.Enter liver, heart channel.Heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control pediatric epilepsy scared Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclamposia.
Cornu Saigae Tataricae: nature and flavor are salty, cold.Return liver, heart channel.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, loose blood removing toxic substances.For the hot infantile convulsion of height, coma convulsion is fainted, and eclamposia is twitched, and epilepsy is gone mad, and has a headache dizzy, cataract, maculae caused by violent heat pathogen, carbuncle sore tumefacting virus.
Radix Gentianae: bitter, cold.Gui Jing: return liver, gallbladder meridian.Function cures mainly: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
Carapax Eretmochelydis: nature and flavor are sweet; Salty; Cold in nature, return careful; Liver Channel, function cures mainly: suppressing the hyperactive liver is calmed the frightened; Heat-clearing and toxic substances removing.The high heat of main calentura; Unconsciousness and delirium is twitched; Pediatric epilepsy scared; Dizzy; Vexed insomnia; Carbuncle sore tumefacting virus.
The Rhizoma Pinelliae: dampness through expectorant, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Control damp-phlegm cold drink, vomiting regurgitation, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness.
Pericarpium Citri Reticulatae: warm in nature, bitter in the mouth, pungent.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough ant phlegm.Herba Houttuyniae: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, pus infections, carbuncle, eczema.
Poria: sweet light is flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Rhizoma Atractylodis: arduous, temperature.Enter spleen, stomach warp.Spleen invigorating, dampness, resolving depression, wards off dirty.Control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, and seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.
Cortex Magnoliae Officinalis: toil, temperature.Enter spleen, stomach, large intestine channel.Have removing dampness intestinal stasis relieving, circulation of qi promoting relievingd asthma, wind dispelling analgesic effect.
Cortex Mori: nature and flavor are sweet; Pungent; Cold in nature, return through lung; Spleen channel, function cures mainly: eliminating pathogen from the lung for relieving asthma; Inducing diuresis to remove edema.Main lung-heat breathes heavily expectorant; Diseases caused by retention of fluid stops lung; Distension dyspnea with rapid respiration; Edema; Foot gas; Dysuria
Radix Saposhnikoviae: Xin Gan, temperature.Enter bladder, lung, spleen channel.Deliver and dispel the wind, victory is wet, pain relieving. and control affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached.
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Radix Ginseng: sweet in the mouth, tepor, nontoxic.Enter spleen, lung meridian.Strongly invigorating primordial QI, promotes the production of body fluid Gu de-, calms the nerves.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, and empty cough with asthma is urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
The Radix Paeoniae Alba: bitter, sour, is slightly cold.Gui Jing: return liver, spleen channel.Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Colla Corii Asini: nature and flavor are sweet is flat.Return lung, liver, kidney channel.Function cures mainly: YIN nourishing of enriching blood, and moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, flesh flaccidity is unable, dysphoria and insomnia, stirring-up of pathogenic wind in the interior resulting from deficiency, xeropulmonary cough, and chronic cough is spat blood, haematemesis hematuria, metrorrhagia of having blood in stool, vaginal bleeding during pregnancy.
Radix Polygoni Multiflori: nature and flavor are bitter, sweet, puckery, temperature.Return liver, the heart, kidney channel.Function cures mainly: removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.
Caulis Spatholobi: bitter, micro-sweet, temperature; Return Liver Channel.Enrich blood and invigorate blood circulation, dredge the meridian passage.This product abnormal smells from the patient is soft, walks to keep and has both, and can change cloudy hemopoietic, promoting the flow of QI-blood by warming the meridian, promoting blood circulation to remove obstruction in the collateral, push away Chen Zhixin, embellish but not dry, tonify without causing stagnation, row and mend broken feature, and to the rheumatic arthralgia caused by blood deficiency, all cards of stasis pain and gynecological, all have good effect.
Radix Puerariae: nature and flavor are sweet, pungent, cool.Return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Function cures mainly: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Fructus Viticis: nature and flavor are pungent, bitter, are slightly cold.Return bladder, liver, stomach warp.Function cures mainly: dispelling wind and heat pathogens, the clear sharp head.For anemopyretic cold headache, gingivitis, the many tear of conjunctival congestion, poor vision, has a dizzy spell.
Radix Glycyrrhizae: sweet, flat.Gui Jing: GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Traditional medicine is thought, hypertension is primarily of caused by the disorder of QI and blood of liver meridians, yin and yang imbalance; In theory of Chinese medical science, its pathogenesis is wind, fire, expectorant, the stasis of blood, empty caused blood pressure rising, the reason of hypertension incidence is mainly impairment of the kidney, depressed rage impairing the liver causes, for the etiology and pathogenesis of primary disease, our with Pericarpium Pyri, Fructus Gardeniae, embryo nelumbinis, Radix Scutellariae clearing away heart-fire, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Colla Corii Asini, Radix Polygoni Multiflori, Caulis Spatholobi, Radix Puerariae nourishing blood and promoting blood circulation; Fructus Atriplicis Sibiricae, Flos Chrysanthemi, Ramulus Uncariae Cum Uncis, Cornu Saigae Tataricae, Radix Gentianae, Carapax Eretmochelydis suppressing the hyperactive liver to relieve the wind syndrome etc.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, all medicine compatibilities, play the effects such as nourishing blood and promoting blood circulation, suppressing the hyperactive liver to relieve the wind syndrome, damp eliminating diuretic altogether.Blood pressure lowering effect is obvious, stable curative effect, and has the symptom such as headache, dizziness, cerebral infarction, limbs fatigue that hypertension causes and well treat remission effect, solve hypertension easily repeatedly, the difficult medical problem that heals of refractory.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
1, clinical data: pure patients with hypertension 120 example, age 34-75 year between, wherein first phase hypertension (160-100mmhg) 46 example, two, three phase hypertension (180-120mmhg) 64 example.
2, diagnostic criteria: the standard of current domestic hypertensive diagnosis employing Chinese Treatment Guidelines for Hypertension suggestion in 2000:
Classification Systolic pressure (mmHg) Diastolic pressure (mmHg)
Normal arterial pressure <120 <80
Normal high level 120~139 80~89
Hypertension ≥140 ≥90
1 grade of hypertension (slightly) 140~159 90~99
2 grades of hypertension (moderate) 160~179 100~109
3 grades of hypertension (severe) ≥180 ≥110
Isolated systolic hypertension ≥140 <90
3, efficacy assessment standard:
Effective: 1. diastolic pressure more than decline 10mmHg, though and reach normal range diastolic pressure and be not down to normally decline 20mmHg or more, wherein 1 must be possessed.
Effective: 1. diastolic pressure declines not as good as 10mmHg, but reaches normal range; 2. diastolic pressure comparatively treats front decline 10-19mmHg, but does not reach normal range; 3. systolic pressure comparatively treats front more than decline 30mmHg, must possess wherein 1.
Invalid: not reach above standard person.
4, Therapeutic Method: take medicine of the present invention, soak by water, takes at twice sooner or later.It within 15 days, is 1 course for the treatment of.
5, therapeutic outcome: cure 92, cure rate 76.7%; Effective 20 people, obvious effective rate 16.7%; Effective 8 people, total effective rate 100%.
In sum, the present invention is used for the treatment of hypertensive Chinese medicine composition, through clinical trial, shows that it effectively can suppress hypertension, improves other symptom, sign that patient causes because of hypertension, effective percentage up to 100%, and without obvious toxic-side effects.
Model case
Case 1: high so-and-so, man, 57 years old, hypertension 1 year, did not give treatment, and since nearly one month, dizzy, cervicodynia, has numbness during two upper limb, companion see weak, dynamic then from dropping sweat, breathe hard, poor appetite.Look into pale and tender tongue, white and thin fur, while there is indentation, deep,thready and forceless pulse.Measuring blood pressure 160/95mmHg.Two examine: dizziness subtracts greatly, and remaining disease also all has and alleviates, and tongue arteries and veins is the same, measuring blood pressure 150/90mmHg.Take two courses for the treatment of of medicine of the present invention, have numbness all to disappear when dizziness, cervicodynia, two upper limb, sweating obviously reduces, weak improvement, and appetite increases.Measuring blood pressure 140/85mmHg, hyoid tooth trace disappears, deep pulse.Continue to take one the course for the treatment of consolidate curative effect, clinical symptoms disappears follow up a case by regular visits to 1 year completely, without recurrence.
Case 2: Lin, female, 40 years old, unit organization health check-up found: blood pressure 145/90mmHg, and kidney color ultrasound is shown: two kidney is slight hydrops.Take two courses for the treatment of of medicine of the present invention, measuring blood pressure 135/84mmHg, kidney color ultrasound is shown: two kidney is without exception.Continue to take one the course for the treatment of consolidate curative effect.Follow up a case by regular visits to half a year blood pressure always at about 130/80mmHg, hydronephrosis does not also recur again.
Case 3: Wang, man, 48 years old, discontinuity dizziness, headache 6 years, increased the weight of 3 days.Without obvious inducement, patient occurs that discontinuity is dizzy, headache, dizzy nonrotary, headache is in distending pain, neck temples is very, companion's Nausea and vomiting, tinnitus, after exciting or tired, symptom obviously increases the weight of, and can alleviate after rest, without lumbago, oliguria, hematuria, edema, the hyperhidrosis of paroxysmal cardiopalmus, unable, the specific drugs such as non-long-term steroid.Take formula Chinese medicine composition of the present invention, first the giddy course for the treatment of, headache improve; Second the dizziness course for the treatment of, headache, Nausea and vomiting, tinnitus symptom obviously improve; 3rd the course for the treatment of above symptom substantially disappear, there is dizziness once in a while; After 4th course for the treatment of, symptom disappears completely; After 2 months, take again two courses for the treatment of, returned to one's perfect health.Follow up a case by regular visits to 1 year, be careful in one's diet at ordinary times and rest, disease is without recurrence.
Detailed description of the invention
Embodiment 1:
One treats hypertensive medicine, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 15, Folium Nelumbinis 15, Rhizoma Gastrodiae 15, Semen Cassiae 15, Pericarppium arachidis hypogaeae 15, Herba Siegesbeckiae 15, seedling of Fructus Cucumidis sativi 15, Spica Prunellae 15, radix linderae 15, black Fructus Mori 15, Bulbus Allii 15, Caulis Bambusae In Taenia 10, Radix Rehmanniae Preparata 10, Rhizoma Dioscoreae 10, Pericarpium Pyri 10, Fructus Gardeniae 10, embryo nelumbinis 10, Radix Scutellariae 5, Fructus Atriplicis Sibiricae 5, Flos Chrysanthemi 5, Ramulus Uncariae Cum Uncis 5, Cornu Saigae Tataricae 5, Radix Gentianae 5, Carapax Eretmochelydis 5, the Rhizoma Pinelliae 5, Pericarpium Citri Reticulatae 5, Poria 5, Rhizoma Atractylodis 5, Cortex Magnoliae Officinalis 5, Cortex Mori 5, Radix Saposhnikoviae 5, the Radix Astragali 5, Radix Ginseng 5, Radix Angelicae Sinensis 5, the Radix Paeoniae Alba 5, Colla Corii Asini 5, Radix Polygoni Multiflori 5, Caulis Spatholobi 5, Radix Puerariae 5, Rhizoma Chuanxiong 5, Rhizoma Corydalis 5, Fructus Viticis 5, Radix Glycyrrhizae 5.
Preparation method:
1. raw material is taken according to the above-mentioned weight portion stated;
2. by step 1. in the raw material that takes add three times of water soakings 2 hours, decocting in water 30 minutes, pours out medicinal liquid; Add decocting in water again 30 minutes, pour out medicinal liquid; Twice medicinal liquid amalgamation rises, and cools completely, and obtains the hypertensive medicine for the treatment of of the present invention.
Instructions of taking: respectively at half an hour before breakfast, takes for after supper two hours.Serveing on 15 days is a course for the treatment of.
Embodiment 2
One treats hypertensive medicine, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 25, Folium Nelumbinis 25, Rhizoma Gastrodiae 25, Semen Cassiae 25, Pericarppium arachidis hypogaeae 25, Herba Siegesbeckiae 25, seedling of Fructus Cucumidis sativi 25, Spica Prunellae 25, radix linderae 25, black Fructus Mori 25, Bulbus Allii 25, Caulis Bambusae In Taenia 20, Radix Rehmanniae Preparata 20, Rhizoma Dioscoreae 20, Pericarpium Pyri 20, Fructus Gardeniae 20, embryo nelumbinis 20, Radix Scutellariae 20, Fructus Atriplicis Sibiricae 20, Flos Chrysanthemi 20, Ramulus Uncariae Cum Uncis 20, Cornu Saigae Tataricae 20, Radix Gentianae 20, Carapax Eretmochelydis 20, the Rhizoma Pinelliae 15, Pericarpium Citri Reticulatae 15, Poria 15, Rhizoma Atractylodis 15, Cortex Magnoliae Officinalis 15, Cortex Mori 15, Radix Saposhnikoviae 15, the Radix Astragali 15, Radix Ginseng 15, Radix Angelicae Sinensis 15, the Radix Paeoniae Alba 10, Colla Corii Asini 10, Radix Polygoni Multiflori 10, Caulis Spatholobi 10, Radix Puerariae 10, Rhizoma Chuanxiong 10, Rhizoma Corydalis 10, Fructus Viticis 10, Radix Glycyrrhizae 10.
Preparation and instructions of taking: with example 1.
Embodiment 3:
One treats hypertensive medicine, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 20, Folium Nelumbinis 20, Rhizoma Gastrodiae 20, Semen Cassiae 20, Pericarppium arachidis hypogaeae 20, Herba Siegesbeckiae 20, seedling of Fructus Cucumidis sativi 20, Spica Prunellae 20, radix linderae 20, black Fructus Mori 20, Bulbus Allii 20, Caulis Bambusae In Taenia 15, Radix Rehmanniae Preparata 15, Rhizoma Dioscoreae 15, Pericarpium Pyri 15, Fructus Gardeniae 15, embryo nelumbinis 15, Radix Scutellariae 10, Fructus Atriplicis Sibiricae 10, Flos Chrysanthemi 10, Ramulus Uncariae Cum Uncis 10, Cornu Saigae Tataricae 10, Radix Gentianae 10, Carapax Eretmochelydis 10, the Rhizoma Pinelliae 10, Pericarpium Citri Reticulatae 10, Poria 10, Rhizoma Atractylodis 10, Cortex Magnoliae Officinalis 10, Cortex Mori 10, Radix Saposhnikoviae 10, the Radix Astragali 10, Radix Ginseng 10, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 8, Colla Corii Asini 8, Radix Polygoni Multiflori 8, Caulis Spatholobi 8, Radix Puerariae 8, Rhizoma Chuanxiong 8, Rhizoma Corydalis 8, Fructus Viticis 8, Radix Glycyrrhizae 8.
Preparation and instructions of taking: with example 1.

Claims (5)

1. the hypertensive medicine for the treatment of, it is characterized in that, be made up of the Chinese medicine of following weight portion: Stigma Maydis 15-25, Folium Nelumbinis 15-25, Rhizoma Gastrodiae 15-25, Semen Cassiae 15-25, Pericarppium arachidis hypogaeae 15-25, Herba Siegesbeckiae 15-25, seedling of Fructus Cucumidis sativi 15-25, Spica Prunellae 15-25, radix linderae 15-25, black Fructus Mori 15-25, Bulbus Allii 15-25, Caulis Bambusae In Taenia 10-20, Radix Rehmanniae Preparata 10-20, Rhizoma Dioscoreae 10-20, Pericarpium Pyri 10-20, Fructus Gardeniae 10-20, embryo nelumbinis 10-20, Radix Scutellariae 5-20, Fructus Atriplicis Sibiricae 5-20, Flos Chrysanthemi 5-20, Ramulus Uncariae Cum Uncis 5-20, Cornu Saigae Tataricae 5-20, Radix Gentianae 5-20, Carapax Eretmochelydis 5-20, Rhizoma Pinelliae 5-15, Pericarpium Citri Reticulatae 5-15, Poria 5-15, Rhizoma Atractylodis 5-15, Cortex Magnoliae Officinalis 5-15, Cortex Mori 5-15, Radix Saposhnikoviae 5-15, Radix Astragali 5-15, Radix Ginseng 5-15, Radix Angelicae Sinensis 5-15, Radix Paeoniae Alba 5-10, Colla Corii Asini 5-10, Radix Polygoni Multiflori 5-10, Caulis Spatholobi 5-10, Radix Puerariae 5-10, Rhizoma Chuanxiong 5-10, Rhizoma Corydalis 5-10, Fructus Viticis 5-10, Radix Glycyrrhizae 5-10.
2. the hypertensive medicine for the treatment of according to claim 1, is characterized in that, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 15, Folium Nelumbinis 15, Rhizoma Gastrodiae 15, Semen Cassiae 15, Pericarppium arachidis hypogaeae 15, Herba Siegesbeckiae 15, seedling of Fructus Cucumidis sativi 15, Spica Prunellae 15, radix linderae 15, black Fructus Mori 15, Bulbus Allii 15, Caulis Bambusae In Taenia 10, Radix Rehmanniae Preparata 10, Rhizoma Dioscoreae 10, Pericarpium Pyri 10, Fructus Gardeniae 10, embryo nelumbinis 10, Radix Scutellariae 5, Fructus Atriplicis Sibiricae 5, Flos Chrysanthemi 5, Ramulus Uncariae Cum Uncis 5, Cornu Saigae Tataricae 5, Radix Gentianae 5, Carapax Eretmochelydis 5, the Rhizoma Pinelliae 5, Pericarpium Citri Reticulatae 5, Poria 5, Rhizoma Atractylodis 5, Cortex Magnoliae Officinalis 5, Cortex Mori 5, Radix Saposhnikoviae 5, the Radix Astragali 5, Radix Ginseng 5, Radix Angelicae Sinensis 5, the Radix Paeoniae Alba 5, Colla Corii Asini 5, Radix Polygoni Multiflori 5, Caulis Spatholobi 5, Radix Puerariae 5, Rhizoma Chuanxiong 5, Rhizoma Corydalis 5, Fructus Viticis 5, Radix Glycyrrhizae 5.
3. the hypertensive medicine for the treatment of according to claim 1, is characterized in that, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 25, Folium Nelumbinis 25, Rhizoma Gastrodiae 25, Semen Cassiae 25, Pericarppium arachidis hypogaeae 25, Herba Siegesbeckiae 25, seedling of Fructus Cucumidis sativi 25, Spica Prunellae 25, radix linderae 25, black Fructus Mori 25, Bulbus Allii 25, Caulis Bambusae In Taenia 20, Radix Rehmanniae Preparata 20, Rhizoma Dioscoreae 20, Pericarpium Pyri 20, Fructus Gardeniae 20, embryo nelumbinis 20, Radix Scutellariae 20, Fructus Atriplicis Sibiricae 20, Flos Chrysanthemi 20, Ramulus Uncariae Cum Uncis 20, Cornu Saigae Tataricae 20, Radix Gentianae 20, Carapax Eretmochelydis 20, the Rhizoma Pinelliae 15, Pericarpium Citri Reticulatae 15, Poria 15, Rhizoma Atractylodis 15, Cortex Magnoliae Officinalis 15, Cortex Mori 15, Radix Saposhnikoviae 15, the Radix Astragali 15, Radix Ginseng 15, Radix Angelicae Sinensis 15, the Radix Paeoniae Alba 10, Colla Corii Asini 10, Radix Polygoni Multiflori 10, Caulis Spatholobi 10, Radix Puerariae 10, Rhizoma Chuanxiong 10, Rhizoma Corydalis 10, Fructus Viticis 10, Radix Glycyrrhizae 10.
4. the hypertensive medicine for the treatment of according to claim 1, is characterized in that, is made up of the Chinese medicine of following weight portion:
Stigma Maydis 20, Folium Nelumbinis 20, Rhizoma Gastrodiae 20, Semen Cassiae 20, Pericarppium arachidis hypogaeae 20, Herba Siegesbeckiae 20, seedling of Fructus Cucumidis sativi 20, Spica Prunellae 20, radix linderae 20, black Fructus Mori 20, Bulbus Allii 20, Caulis Bambusae In Taenia 15, Radix Rehmanniae Preparata 15, Rhizoma Dioscoreae 15, Pericarpium Pyri 15, Fructus Gardeniae 15, embryo nelumbinis 15, Radix Scutellariae 10, Fructus Atriplicis Sibiricae 10, Flos Chrysanthemi 10, Ramulus Uncariae Cum Uncis 10, Cornu Saigae Tataricae 10, Radix Gentianae 10, Carapax Eretmochelydis 10, the Rhizoma Pinelliae 10, Pericarpium Citri Reticulatae 10, Poria 10, Rhizoma Atractylodis 10, Cortex Magnoliae Officinalis 10, Cortex Mori 10, Radix Saposhnikoviae 10, the Radix Astragali 10, Radix Ginseng 10, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 8, Colla Corii Asini 8, Radix Polygoni Multiflori 8, Caulis Spatholobi 8, Radix Puerariae 8, Rhizoma Chuanxiong 8, Rhizoma Corydalis 8, Fructus Viticis 8, Radix Glycyrrhizae 8.
5., according to a preparation method for the arbitrary described hypertensive medicine for the treatment of of claim 1-4, it is characterized in that, comprise the following steps:
1. raw material is taken according to the arbitrary described weight portion of claim 1-4;
2. by step 1. in the raw material that takes add three times of water soakings 2 hours, decocting in water 30 minutes, pours out medicinal liquid; Add decocting in water again 30 minutes, pour out medicinal liquid; Twice medicinal liquid amalgamation rises, and cools completely, and obtains the hypertensive medicine for the treatment of of the present invention.
CN201510203037.9A 2015-04-24 2015-04-24 Medicine for treating hypertension and preparation method thereof Pending CN104800634A (en)

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CN105106911A (en) * 2015-09-25 2015-12-02 全椒贡菊园茶厂 Traditional Chinese medicine for treating hypertension
CN105106910A (en) * 2015-09-25 2015-12-02 全椒贡菊园茶厂 Traditional Chinese medicine with stable blood pressure reducing effect
CN105748957A (en) * 2016-04-08 2016-07-13 烟台市蓝洋之草医药生物科技有限公司 Application of medicine composition in preparation of medicine for treating hypertension
CN107456546A (en) * 2017-08-15 2017-12-12 晁伟岩 It is capable of the preparation method of the oat oral liquid of three high drop
WO2019210633A1 (en) * 2018-09-02 2019-11-07 Ge Jianxia Improved fabric

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106911A (en) * 2015-09-25 2015-12-02 全椒贡菊园茶厂 Traditional Chinese medicine for treating hypertension
CN105106910A (en) * 2015-09-25 2015-12-02 全椒贡菊园茶厂 Traditional Chinese medicine with stable blood pressure reducing effect
CN105748957A (en) * 2016-04-08 2016-07-13 烟台市蓝洋之草医药生物科技有限公司 Application of medicine composition in preparation of medicine for treating hypertension
CN107456546A (en) * 2017-08-15 2017-12-12 晁伟岩 It is capable of the preparation method of the oat oral liquid of three high drop
CN107456546B (en) * 2017-08-15 2018-11-13 潘柳臻 It is capable of the preparation method of the oat oral solution of lower hyperlipidemia, hypertension, hyperglycemia
WO2019210633A1 (en) * 2018-09-02 2019-11-07 Ge Jianxia Improved fabric

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