CN103006980A - Chinese medicinal composition for treating distention and fullness - Google Patents
Chinese medicinal composition for treating distention and fullness Download PDFInfo
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Abstract
Description
技术领域 technical field
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗痞满的中药组合物。 The invention relates to a medical preparation of undetermined structure of traditional herbal medicine, especially a traditional Chinese medicine composition for treating fullness.
背景技术 Background technique
痞满多指胸腔部痞塞满闷,而外无胀急之形。西医学中的慢性胃炎、胃神经官能症、胃下垂、消化不良等疾病,当出现以胃脘部痞塞,满闷不舒为主要表现时,都可以痞满证辩证治疗。但是西医治疗痞满仅针对单一症状,无法从根本上治愈痞满。 Fullness of the chest usually refers to the fullness of the chest cavity, but there is no appearance of urgency outside. Chronic gastritis, gastric neurosis, gastroptosis, indigestion and other diseases in western medicine can all be treated dialectically based on the syndrome of fullness and fullness when the main manifestations are fullness in the epigastric cavity and fullness and discomfort. However, Western medicine treatment of fullness is only aimed at a single symptom, and cannot fundamentally cure fullness.
中医认为,脾胃同居中焦,脾主升清,胃主降浊,共司水谷的纳运和吸收,清升浊降,纳运如常,则胃气调畅。若因表邪内陷入里,饮食不节,痰湿阻滞,情志失调,或脾胃虚弱等各种原因导致脾胃损伤,升降失司,胃气壅塞,即可发生痞满。 Traditional Chinese medicine believes that the spleen and stomach are located in the middle burner, the spleen governs the promotion of clearness, and the stomach governs the reduction of turbidity, and they are in charge of the transportation and absorption of water and grains. Spleen and stomach damage, loss of ascending and descending, and gastric qi congestion can occur due to various reasons such as external evils sinking in, improper diet, phlegm dampness, emotional disorders, or weak spleen and stomach.
根据中医理论,针对痞满的发病机理,进行辩证配伍组方,以达到标本兼治的目的。 According to the theory of traditional Chinese medicine, according to the pathogenesis of fullness, dialectical compatibility prescriptions are carried out to achieve the purpose of treating both symptoms and root causes.
发明内容 Contents of the invention
为了克服现有技术的不足,本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗痞满的中药组合物。 In order to overcome the shortcomings of the prior art, the invention provides a traditional Chinese medicine composition for treating fullness with convenient preparation, wide drug sources, low cost, remarkable curative effect, reliable effect and no side effects.
本发明解决其技术问题所采用的技术方案是:一种治疗痞满的中药组合物,其特征在于:其是由下列重量份配比的中药原料组成:柴胡10-25份、肉桂10-30份、山茱萸10-30份、川楝子5-15份、枳实5-15份、鸡内金10-25份、陈皮10-25份、赤芍5-15份、白芍5-15份、厚朴5-15份、生大黄3-10份、瓜蒌皮5-20份、苍术10-25份、白蒺藜5-15份、山药10-30份、猪苓5-15份、木香5-15份、甘草5-15份。 The technical solution adopted by the present invention to solve the technical problem is: a Chinese medicine composition for treating fullness, characterized in that it is composed of the following Chinese medicine raw materials in proportions by weight: 10-25 parts of Bupleuri, 10-25 parts of Cinnamon 30 parts, 10-30 parts of dogwood, 5-15 parts of toosendan, 5-15 parts of citrus aurantium, 10-25 parts of gallinaceous gold, 10-25 parts of tangerine peel, 5-15 parts of red peony, 5-15 parts of white peony 5-15 parts of Magnolia officinalis, 3-10 parts of raw rhubarb, 5-20 parts of melon peel, 10-25 parts of herb, 5-15 parts of Tribulus terrestris, 10-30 parts of Chinese yam, 5-15 parts of Polyporus, Woody 5-15 parts, licorice 5-15 parts.
本发明的优选技术方案是:一种治疗痞满的中药组合物,其特征在于:其是由下列重量份配比的中药原料组成:柴胡15份、肉桂20份、山茱萸20份、川楝子10份、枳实10份、鸡内金15份、陈皮15份、赤芍8份、白芍10份、厚朴10份、生大黄6份、瓜蒌皮12份、苍术15份、白蒺藜10份、山药20份、猪苓10份、木香8份、甘草10份。 The preferred technical scheme of the present invention is: a traditional Chinese medicine composition for treating fullness, characterized in that: it is composed of the following traditional Chinese medicine raw materials in proportions by weight: 15 parts of Bupleurum bupleuri, 20 parts of cinnamon, 20 parts of Cornus officinalis, toosendan 10 parts of fruit, 10 parts of citrus aurantium, 15 parts of gallinaceous gold, 15 parts of tangerine peel, 8 parts of red peony, 10 parts of white peony, 10 parts of Magnolia officinalis, 6 parts of raw rhubarb, 12 parts of melon skin, 15 parts of atractylodes, 10 parts of Tribulus terrestris, 20 parts of yam, 10 parts of Polyporus, 8 parts of woody fragrance, 10 parts of licorice.
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:柴胡具有疏散退热、升阳舒肝的功效;肉桂具有补火助阳、散寒止痛、活血通经的功效;山茱萸具有补益肝肾、涩精固脱的功效;川楝子具有疏肝泄热、行气止痛、杀虫的功效;枳实具有化痰散痞、破气消积的功效;鸡内金具有消食健胃、化积排石、固摄缩尿、涩精止遗的功效;陈皮具有理气健脾、调中利水、燥湿化痰的功效;赤芍具有清热凉血、散瘀止痛的功效;白芍具有养血柔肝、缓中止痛、敛阴收汗的功效;厚朴具有行气消积、燥湿除满、降逆平喘的功效;生大黄具有泻火消积、清热解毒、凉血止血、祛瘀止咳的功效;瓜蒌皮具有润肺化痰、利气宽胸的功效;苍术具有燥湿健脾的功效;白蒺藜具有疏肝解郁、祛风明目的功效;山药具有健脾补肺、益胃补肾、固肾益精、聪耳明目、助五脏、强筋骨、长志安神、延年益寿的功效;猪苓具有利水渗湿的功效;木香具有行气止痛、调中导滞的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏健脾和胃、疏肝理气、固肾益精、行气消积之功效,对痞满达到标本兼治的目的。 The traditional Chinese medicine composition of the invention is a prescription of selected medicines under the guidance of traditional Chinese medicine theory and clinical experience. In the traditional Chinese medicine composition of the present invention: Radix Bupleurum has the effects of evacuating and reducing fever, raising yang and soothing the liver; cinnamon has the effects of nourishing fire and supporting yang, dispelling cold and relieving pain, promoting blood circulation and promoting menstruation; Cornus officinalis has the effects of nourishing liver and kidney, astringent essence and detoxification ; Toosendan has the effects of soothing the liver and expel heat, promoting qi and relieving pain, and killing insects; Efficacy of urination and astringent essence to relieve enuresis; tangerine peel has the effects of regulating qi and invigorating the spleen, regulating the middle and diuresis, drying dampness and resolving phlegm; red peony root has the effect of clearing heat and cooling blood, dispelling blood stasis and relieving pain; , the effect of astringing yin and sweating; Magnolia officinalis has the effect of promoting qi and eliminating accumulation, drying dampness and eliminating fullness, reducing adverse events and relieving asthma; The skin has the effects of moistening the lungs and reducing phlegm, benefiting qi and broadening the chest; Atractylodes atractylodes has the effect of drying dampness and invigorating the spleen; Benefit essence, sharpen ears and eyesight, help the five viscera, strengthen bones and muscles, calm the nerves, and prolong life; Polyporus has the effect of diuresis and dampness; woody fragrance has the effect of promoting qi and relieving pain, regulating the middle and guiding stagnation; licorice has the effect of nourishing the spleen and benefiting the spleen. Qi, clearing heat and detoxification, eliminating phlegm and relieving cough, and harmonizing the effects of various medicines. The medicinal components in the composition of the present invention are dialectically compatible, complement each other in action, and have a synergistic effect. They have the effects of invigorating the spleen and harmonizing the stomach, soothing the liver and regulating qi, strengthening the kidney and replenishing essence, and promoting qi and eliminating accumulation. The purpose of governing.
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率96%,治愈率达67.9%。 The components of the composition of the invention all adopt natural traditional Chinese medicine raw materials, and the preparation is simple, the medicine source is wide, and the cost is low. It follows the principle of prescription medication in traditional Chinese medicine, and the various component medicines are taken by decoction. It has been verified by clinical application that its curative effect is remarkable, its action is reliable, its properties are mild, and there are no toxic or side effects. The total effective rate is 96%, and the cure rate is 67.9%.
具体实施方式 Detailed ways
下面结合实施例对本发明做进一步说明。 The present invention will be further described below in conjunction with embodiment.
实施例1 Example 1
一种治疗痞满的中药组合物,其是由下列重量配比的中药原料组成:柴胡15g、肉桂20g、山茱萸20g、川楝子10g、枳实10g、鸡内金15g、陈皮15g、赤芍8g、白芍10g、厚朴10g、生大黄6g、瓜蒌皮12g、苍术15g、白蒺藜10g、山药20g、猪苓10g、木香8g、甘草10g。 A traditional Chinese medicine composition for treating fullness, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum bupleuri 15g, cinnamon 20g, dogwood 20g, toosendan 10g, citrus aurantium 10g, chicken gold 15g, tangerine peel 15g, red Paeoniae 8g, Paeoniae Alba 10g, Magnolia officinalis 10g, Rhubarb 6g, Trichosanthes bark 12g, Atractylodes 15g, Tribulus terrestris 10g, Chinese yam 20g, Polyporus 10g, Woody 8g, Licorice 10g.
实施例2 Example 2
一种治疗痞满的中药组合物,其是由下列重量配比的中药原料组成:柴胡25g、肉桂10g、山茱萸15g、川楝子15g、枳实12g、鸡内金20g、陈皮10g、赤芍15g、白芍5g、厚朴12g、生大黄5g、瓜蒌皮15g、苍术20g、白蒺藜5g、山药25g、猪苓12g、木香5g、甘草5g。 A traditional Chinese medicine composition for treating fullness, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: 25g of Bupleurum bupleuri, 10g of cinnamon, 15g of dogwood, 15g of toosendan, 12g of citrus aurantium, 20g of gallinaceous gold, 10g of tangerine peel, Paeoniae 15g, Paeoniae Alba 5g, Magnolia officinalis 12g, Rhubarb 5g, Tribulus 15g, Atractylodes 20g, Tribulus terrestris 5g, Chinese yam 25g, Polyporus 12g, Woody 5g, Licorice 5g.
实施例3 Example 3
一种治疗痞满的中药组合物,其是由下列重量配比的中药原料组成:柴胡20g、肉桂15g、山茱萸25g、川楝子8g、枳实15g、鸡内金10g、陈皮25g、赤芍5g、白芍12g、厚朴8g、生大黄10g、瓜蒌皮5g、苍术25g、白蒺藜12g、山药10g、猪苓5g、木香15g、甘草8g。 A traditional Chinese medicine composition for treating fullness, which is composed of the following traditional Chinese medicine raw materials in the following weight proportions: 20g of Bupleurum bupleuri, 15g of cinnamon, 25g of dogwood, 8g of Toosendan, 15g of Citrus aurantium, 10g of Gallus gallis, 25g of tangerine peel, Paeoniae 5g, Paeoniae Alba 12g, Magnolia officinalis 8g, Raw rhubarb 10g, Tribulus peel 5g, Atractylodes 25g, Tribulus terrestris 12g, Chinese yam 10g, Polyporus 5g, Woody 15g, Licorice 8g.
实施例4 Example 4
一种治疗痞满的中药组合物,其是由下列重量配比的中药原料组成:柴胡10g、肉桂25g、山茱萸10g、川楝子12g、枳实5g、鸡内金12g、陈皮20g、赤芍10g、白芍8g、厚朴15g、生大黄3g、瓜蒌皮20g、苍术10g、白蒺藜8g、山药15g、猪苓15g、木香12g、甘草12g。 A traditional Chinese medicine composition for treating fullness, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum bupleuri 10g, cinnamon 25g, dogwood 10g, toosendan 12g, citrus aurantium 5g, gallinaceous gold 12g, tangerine peel 20g, red 10g of peony root, 8g of white peony root, 15g of Magnolia officinalis, 3g of raw rhubarb, 20g of Tribulus officinalis, 10g of herb, 8g of Tribulus terrestris, 15g of Chinese yam, 15g of Polyporus 12g, 12g of woody root, 12g of licorice.
实施例5 Example 5
一种治疗痞满的中药组合物,其是由下列重量配比的中药原料组成:柴胡12g、肉桂30g、山茱萸30g、川楝子5g、枳实8g、鸡内金25g、陈皮12g、赤芍12g、白芍15g、厚朴5g、生大黄8g、瓜蒌皮10g、苍术5g、白蒺藜15g、山药30g、猪苓8g、木香10g、甘草15g。 A traditional Chinese medicine composition for treating fullness, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum bupleuri 12g, cinnamon 30g, dogwood 30g, toosendan 5g, citrus aurantium 8g, gallinaceous gold 25g, tangerine peel 12g, red Paeoniae 12g, Paeoniae Alba 15g, Magnolia officinalis 5g, Rhubarb 8g, Trichosanthes bark 10g, Atractylodes 5g, Tribulus terrestris 15g, Chinese yam 30g, Polyporus 8g, Woody 10g, Licorice 15g.
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行煎煮。未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。 The traditional Chinese medicine composition in the embodiment of the present invention is prepared according to the conventional water decoction method. The specific method is as follows: put the Chinese medicine raw materials of the prescription into a container, add cold water to cover the surface of the medicine, soak for 15 to 20 minutes, add water to cover the surface of the medicine by about 8 cm, and decoct. Before boiling, use strong fire to decoct, and after boiling, use slow fire to decoct for 20-30 minutes; for the second decoction, add water to cover about 6 cm of the medicine surface, and decoct for 15-20 minutes after the water boils. Decoct twice to remove the residue and extract the juice, and combine.
一种治疗痞满的中药组合物,临床疗效总结: A traditional Chinese medicine composition for the treatment of fullness, clinical curative effect summary:
一、一般性资料:本中药组合物应用于临床观察病例56例,其中男24例,女32例,年龄20~70岁。病程最短者1个周,最长者达2个月,平均25天。 1. General information: This traditional Chinese medicine composition was applied to 56 cases of clinical observation, including 24 males and 32 females, aged 20 to 70 years. The shortest course of disease is 1 week, and the longest is 2 months, with an average of 25 days.
二、诊断标准: 2. Diagnostic criteria:
1、胃痞以胃脘部痞塞,满闷不舒为主症,并有按之柔软,压之不痛,望无胀形的特点; 1. Stomach fullness is mainly characterized by stuffy stomach, fullness and discomfort, and it is soft to press, not painful to press, and no bulge;
2、起病缓慢,时轻时重,呈反复发作的慢性过程; 2. The onset is slow, sometimes mild and sometimes severe, showing a chronic process of repeated attacks;
3、发病常与饮食、情志、起居、寒温等诱因有关; 3. The onset is often related to diet, emotion, daily life, cold temperature and other inducements;
4、上消化道X线检查、胃液分析、纤维胃镜检查等有助于本病的诊断。需除外胃癌,以及其他病证中出现的痞满症状。 4. Upper gastrointestinal X-ray examination, gastric juice analysis, and fiber optic gastroscopy are helpful for the diagnosis of this disease. Stomach cancer and fullness symptoms in other diseases need to be excluded.
三、用法用量:临床应用时,组合物中的组分、用量根据患者的体重、年龄及症状酌情增减。五天为一疗程,一天一剂,水煎两遍取汁约300ml,分早、晚两次饭前半小时温热服用。 3. Usage and dosage: In clinical application, the components and dosage in the composition can be increased or decreased according to the patient's weight, age and symptoms. Five days is a course of treatment, one dose a day, decocted in water twice, take about 300ml of juice, and take it with warm water half an hour before meals in the morning and evening.
四、疗效标准: 4. Efficacy standard:
1、近期临床治愈:包括下面所有指标: 1. Recent clinical cure: including all the following indicators:
①临床主要症状消失,次要症状消失或基本消失; ① The main clinical symptoms disappear, and the secondary symptoms disappear or basically disappear;
②胃镜复查活动性炎症消失,慢性炎症好转达轻度; ②The active inflammation disappeared after gastroscopy reexamination, and the chronic inflammation improved to mild;
③活检组织病理证实胃镜所见;腺体萎缩、肠化和异型增生复常或消失; ③Biopsy histopathology confirms gastroscopy findings; glandular atrophy, intestinal metaplasia and dysplasia return to normal or disappear;
④胃酸基本恢复正常,胆汁反流消失; ④The gastric acid basically returns to normal, and the bile reflux disappears;
2、显效:包括下面所有指标: 2. Significant effect: including all the following indicators:
①临床主要症状消失,次要症状基本消失; ① The main clinical symptoms disappear, and the secondary symptoms basically disappear;
②胃镜复查黏膜急性炎症基本消失,慢性炎症好转; ②The acute inflammation of the mucous membrane basically disappeared, and the chronic inflammation improved;
③活检组织病理证实胃镜所见;腺体萎缩、肠化和异型增生恢复或减轻达两个级度以上(含两个级度); ③Biopsy histopathology confirms gastroscopy findings; glandular atrophy, intestinal metaplasia and dysplasia recover or reduce to more than two grades (including two grades);
④胃酸分泌功能和胆汁反流改善,达原病异常值的2/3以上; ④Gastric acid secretion function and bile reflux improved, reaching more than 2/3 of the abnormal value of the original disease;
3、有效:包括下面所有指标: 3. Effective: including all the following indicators:
①主要症状明显减轻; ① The main symptoms are significantly relieved;
②胃镜检查见黏膜病变范围缩小1/2以上,炎症有所减轻; ② Gastroscopy shows that the scope of mucosal lesions has shrunk by more than 1/2, and the inflammation has been alleviated;
③活检组织病理证实胃镜所见;急慢性炎症减轻一个级度以上,腺体萎缩,肠化生和异型增生减轻; ③Biopsy histopathology confirms gastroscopy findings; acute and chronic inflammation is alleviated by more than one grade, glandular atrophy, intestinal metaplasia and dysplasia are alleviated;
④胃酸分泌功能和胆汁反流改善,达原病异常值的1/2以上; ④Gastric acid secretion function and bile reflux improved, reaching more than 1/2 of the abnormal value of the original disease;
4、无效:达不到有效标准的病例,但还没有恶化者。 4. Invalid: Cases that do not reach the effective standard, but have not deteriorated.
五、治疗效果:该临床观察病例中,服药1-6个疗程,治愈38例,显效13例,有效3例,无效2例。治疗期间未发生毒副作用。 5. Treatment effect: Among the clinical observation cases, 38 cases were cured, 13 cases were markedly effective, 3 cases were effective, and 2 cases were ineffective after taking the medicine for 1-6 courses of treatment. No toxic side effects occurred during the treatment.
六、典型病例: 6. Typical cases:
病例1: Case 1:
连某,女,56岁,胃脘痞塞,满闷不舒,按之不疼,饮食减少。服用本发明的中药组合物制备的药剂1个疗程,症状基本消失;继续巩固2个疗程,诸症状均消失,治愈。 Lian, female, 56 years old, suffered from abdominal fullness, fullness and discomfort, no pain when pressed, and reduced diet. Take the medicament prepared by the traditional Chinese medicine composition of the present invention for 1 course of treatment, and the symptoms disappear substantially; continue to consolidate for 2 courses of treatment, all symptoms disappear, and the symptoms are cured.
病例2: Case 2:
金某,男,43岁,胃脘痞塞,胸膈满闷,饮食减少,大便不调,消瘦。服用本发明的中药组合物制备的药剂1个疗程,自觉药后胃脘胀满稍减轻;续服2个疗程,胃脘胀满已不明显,饮食增多,食后胃中舒适,大便每天一次,不干不稀;再巩固服用1个疗程,症状消失,食欲增加,精神饱满。 Jin, male, 43 years old, with stuffy stomach, full chest and diaphragm, reduced diet, irregular stool, and weight loss. Taking the medicament prepared by the traditional Chinese medicine composition of the present invention for 1 course of treatment, the fullness of the epigastric cavity is slightly relieved after taking the medicine consciously; after taking 2 courses of treatment, the fullness of the epigastric cavity is no longer obvious, the diet increases, the stomach is comfortable after eating, and the stool is once a day , neither dry nor dilute; take a further course of treatment, the symptoms disappear, the appetite increases, and the spirit is full.
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| CN105456894A (en) * | 2015-12-25 | 2016-04-06 | 梁献彬 | Traditional Chinese medicine instant tea for treating gastrectasia and preparation method thereof |
| CN105456893A (en) * | 2015-12-25 | 2016-04-06 | 梁献彬 | Traditional Chinese medicine pill for treating dispelling gastrectasia and preparation method of traditional Chinese medicine pill |
| CN105535781A (en) * | 2015-12-25 | 2016-05-04 | 梁献彬 | Rice wine for eliminating stomach bloating and preparation method thereof |
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| CN101757581A (en) * | 2008-11-26 | 2010-06-30 | 杨汝静 | Traditional Chinese medicine for treating fullness and distension in abdomen |
| CN102327410A (en) * | 2011-09-17 | 2012-01-25 | 张志红 | Traditional Chinese medicine composition for treating epigastric fullness |
| CN102416137A (en) * | 2011-12-06 | 2012-04-18 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating distention and fullness |
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| CN101757581A (en) * | 2008-11-26 | 2010-06-30 | 杨汝静 | Traditional Chinese medicine for treating fullness and distension in abdomen |
| CN102327410A (en) * | 2011-09-17 | 2012-01-25 | 张志红 | Traditional Chinese medicine composition for treating epigastric fullness |
| CN102416137A (en) * | 2011-12-06 | 2012-04-18 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating distention and fullness |
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| CN105456894A (en) * | 2015-12-25 | 2016-04-06 | 梁献彬 | Traditional Chinese medicine instant tea for treating gastrectasia and preparation method thereof |
| CN105456893A (en) * | 2015-12-25 | 2016-04-06 | 梁献彬 | Traditional Chinese medicine pill for treating dispelling gastrectasia and preparation method of traditional Chinese medicine pill |
| CN105535781A (en) * | 2015-12-25 | 2016-05-04 | 梁献彬 | Rice wine for eliminating stomach bloating and preparation method thereof |
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