CN104995300B - Rna活性和血管通透性的调节 - Google Patents

Rna活性和血管通透性的调节 Download PDF

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CN104995300B
CN104995300B CN201380061417.2A CN201380061417A CN104995300B CN 104995300 B CN104995300 B CN 104995300B CN 201380061417 A CN201380061417 A CN 201380061417A CN 104995300 B CN104995300 B CN 104995300B
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oligonucleotides
seq
mir
bases
oligonucleotide
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CN104995300A (zh
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詹尼弗·甘布尔
马修·瓦达斯
索尔莱夫·默勒
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Centenary Institute of Cancer Medicine and Cell Biology
University of Sydney
MIRRX THERAPEUTICS AS
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Centenary Institute of Cancer Medicine and Cell Biology
University of Sydney
MIRRX THERAPEUTICS AS
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CN201380061417.2A 2012-10-02 2013-10-02 Rna活性和血管通透性的调节 Active CN104995300B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012904297A AU2012904297A0 (en) 2012-10-02 Modulation of RNA activity and vascular permeability
AU2012904297 2012-10-02
AU2012904365A AU2012904365A0 (en) 2012-10-05 Modulation of RNA activity and vascular permeability
AU2012904365 2012-10-05
PCT/AU2013/001129 WO2014053014A1 (en) 2012-10-02 2013-10-02 Modulation of rna activity and vascular permeability

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Publication Number Publication Date
CN104995300A CN104995300A (zh) 2015-10-21
CN104995300B true CN104995300B (zh) 2018-07-17

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US (1) US9879255B2 (enExample)
EP (1) EP2904102B1 (enExample)
JP (1) JP6430945B2 (enExample)
CN (1) CN104995300B (enExample)
AU (1) AU2013327393B2 (enExample)
CA (1) CA2886745A1 (enExample)
WO (1) WO2014053014A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2904102B1 (en) 2012-10-02 2018-11-21 Centenary Institute of Cancer Medicine & Cell Biology Modulation of rna activity and vascular permeability
CN108348539A (zh) * 2015-08-05 2018-07-31 癌症医学和细胞生物学百年研究所 用于治疗肿瘤的方法
CN105861728B (zh) * 2016-06-12 2024-11-19 上海市第十人民医院 循环miRNA作为年龄相关黄斑变性诊断标志物中的应用
WO2025102119A1 (en) * 2023-11-16 2025-05-22 Centenary Institute Of Cancer Medicine And Cell Biology Improvement of blood brain barrier integrity

Citations (4)

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CN101641440A (zh) * 2006-11-23 2010-02-03 米尔克斯治疗有限责任公司 用于调节靶rna活性的寡核苷酸
CN101821390A (zh) * 2007-06-14 2010-09-01 米尔克斯治疗有限责任公司 用于调节靶rna活性的寡核苷酸
WO2010139026A1 (en) * 2009-06-05 2010-12-09 Centenary Institute Of Cancer Medicine And Cell Biology Therapeutic and diagnostic molecules
US20110065778A1 (en) * 2002-02-20 2011-03-17 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Muscarinic Colinergic Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA)

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JP2000143536A (ja) * 1998-11-13 2000-05-23 Nippon Zoki Pharmaceut Co Ltd 抗浮腫剤
CN101232897A (zh) * 2005-06-16 2008-07-30 新藤隆行 含有肾上腺髓质素作为有效成分的血管生成剂
AU2014250708B2 (en) 2006-11-23 2016-11-10 Guangdong Maijinjia Biotechnology Co., Ltd Oligonucleotides for modulating target RNA activity
US20100021914A1 (en) 2006-11-23 2010-01-28 Querdenker Aps Oligonucleotides for modulating target rna activity
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JP6352269B2 (ja) 2012-09-26 2018-07-04 ミルクス セラピューティクス アクティーゼルスカブＭｉｒｒｘ Ｔｈｅｒａｐｅｕｔｉｃｓ Ａ／Ｓ オフターゲットプロファイルの改善されたオリゴマー
EP2904102B1 (en) 2012-10-02 2018-11-21 Centenary Institute of Cancer Medicine & Cell Biology Modulation of rna activity and vascular permeability
CN104902901A (zh) 2012-10-19 2015-09-09 株式会社棱镜制药 使用cbp/连环蛋白的抑制剂治疗过度增殖性和癌前皮肤病

Patent Citations (4)

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US20110065778A1 (en) * 2002-02-20 2011-03-17 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Muscarinic Colinergic Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA)
CN101641440A (zh) * 2006-11-23 2010-02-03 米尔克斯治疗有限责任公司 用于调节靶rna活性的寡核苷酸
CN101821390A (zh) * 2007-06-14 2010-09-01 米尔克斯治疗有限责任公司 用于调节靶rna活性的寡核苷酸
WO2010139026A1 (en) * 2009-06-05 2010-12-09 Centenary Institute Of Cancer Medicine And Cell Biology Therapeutic and diagnostic molecules

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EP2904102A4 (en) 2016-07-06
WO2014053014A1 (en) 2014-04-10
CA2886745A1 (en) 2014-04-10
CN104995300A (zh) 2015-10-21
US20160040160A1 (en) 2016-02-11
US9879255B2 (en) 2018-01-30
EP2904102B1 (en) 2018-11-21
JP6430945B2 (ja) 2018-11-28
EP2904102A1 (en) 2015-08-12
AU2013327393A1 (en) 2015-05-21
JP2015533085A (ja) 2015-11-19
AU2013327393B2 (en) 2019-07-18

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