CN104985814A - High temperature and low temperature combined biological 3D printing spray head - Google Patents
High temperature and low temperature combined biological 3D printing spray head Download PDFInfo
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- CN104985814A CN104985814A CN201510353283.2A CN201510353283A CN104985814A CN 104985814 A CN104985814 A CN 104985814A CN 201510353283 A CN201510353283 A CN 201510353283A CN 104985814 A CN104985814 A CN 104985814A
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Abstract
The invention discloses a high temperature and low temperature combined biological 3D printing spray head. The high temperature and low temperature combined biological 3D printing spray head is provided with a heating and cooling device and can achieve accurate control over various temperatures. The spray head comprises an outer shell, a heat conducting block, heating bars, a cooling piece, cooling fins, a fan, a needle cylinder, a heat conducting block upper baffle, a heat conducting block lower baffle, a spiral cover and a needle head. According to the high temperature and low temperature combined biological 3D printing spray head, the heating bars and the needle cylinder are additionally arranged in the heat conducting block, and materials in the needle cylinder can be heated through the heating bars; meanwhile, the cooling piece is attached to one outer surface of the heat conducting block, the cooling piece is connected with the cooling fins and the fan, and thus the materials in the needle cylinder can be cooled. In this way, printing of the materials at different temperatures can be achieved through one spray head, the structure of the spray head is simplified, and cost is reduced.
Description
Technical field
The present invention relates to a kind of biological 3D printing head towards high/low temperature combination, for Cell and organism file printing, belong to tissue engineering technique and biological 3D printing field.
Background technology
For the treatment of impaired bulk soft tissue and internal organs, it is the very effective methods for the treatment of of one that human tissue organ transplants.But because the problems such as organ donor source shortage, immunological rejection exist, there is the difficulty being difficult to overcome in organ transplant treatment in practice.And the proposition of organizational project opens new approach for solving the problem.Organizational project be by living cells by conforming to someway on the support of biomaterial matrix or preparation, come constructing function tissue substituent.Then, after the tissue substituent of structure being carried out cultivating in patients with implantation body, replace original pathological tissues organ and realize disease treatment to recover physical function.The research of current organization engineering skin and use effective illustration with regard to the good development prospect of organizational project.
Tradition Tissue Engineering Study is limited to cell implanted prosthetics always, namely " is implanted on support by cell " in this organizational project inherent technology link, different types of Cell and organism material accurately cannot be navigated to internal stent different spatial.In fact, along with the propelling of Tissue Engineering Study, research work progressively prolongs life to bulk soft tissue and internal organs aspect, because these tissues and organ are often containing various kinds of cell and biomaterial, and different cell or material have specific spatial arrangement, therefore above-mentioned technical limitation highlights more.
In recent years, the fast development of 3D printing technique, for industry manufacture opens new manufacture production model.In biological field, the technology such as biometric print, cell three-dimensional controlled tissue are also applied and give birth to.These technology have the ability of operation individual cells or single composition microsize drop, can the accurately locus of control operation object and distribution, there is huge meaning for the locus deposition realizing Cell and organism material not of the same race in bulk tissue and organ building process.Therefore, the inexorable trend that biometric print technology is future organization engineering research is developed.And in a typical biometric print machine, one of critical component is exactly the shower nozzle that is shaped.
In order to meet the structure requirement that bulk soft tissue and internal organs require material temperature to differ, need the biological 3D printing head developing the combination of a kind of high/low temperature.
In order to realize the requirement that material temperature height differs, a kind of biological 3D printing head towards high/low temperature combination.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of biological 3D printing head towards high/low temperature combination is provided.
Technical scheme of the present invention is as follows:
A kind of biological 3D towards high/low temperature combination prints spray and has heating and cooling device, can realize the accurate control of various temperature, shower nozzle comprises shell body, heat-conducting block, heating rod, cooling fin, fin, fan, syringe, heat-conducting block overhead gage, heat-conducting block lower baffle plate, spiral cover and syringe needle; Described heat-conducting block is arranged in shell body, and described heating rod is arranged on heat-conducting block inside; Described cooling fin is arranged on heat-conducting block outer surface; Described fin to be arranged on shell body and to contact with cooling fin; Described fan is arranged on fin surface; Described syringe is arranged on heat-conducting block inside; Described heat-conducting block lower baffle plate is arranged between heat-conducting block lower surface and shell body; Described heat-conducting block overhead gage is arranged between the upper surface of heat-conducting block and shell body; Described spiral cover is connected with syringe by screw thread, for convenience detach; Described syringe needle is arranged on bottom syringe.
Described shell body is made up of upper plate, base plate, left plate, right plate, front side board and back side panel, is connected between each block of plate by bolt; Described upper plate has through hole, for installing with heat-conducting block overhead gage; Described base plate has circular hole, passing through for syringe needle; Described left plate and right plate have straight trough mouth, distributing for heat; Described back side panel has square hole, for the installation of fin; The described front side board upper left corner has circular hole, and the supply line for heating rod and cooling fin installs.
Described heating rod quantity is even number, is distributed on heat-conducting block inside, ensures homogeneous heating; The heat that described heating rod produces passes to syringe by heat-conducting block, heats the material in syringe.
Described fin one side fully contacts with the surface of cooling fin, and another side fully contacts with fan; Described cooling fin siphons away the heat of material in syringe by heat-conducting block and passes to fin, then is discharged by heat by fan turning effort, cools material.
Described heat-conducting block does not contact with back side panel with left plate, right plate, front side board, for heat insulation;
Described heat-conducting block overhead gage and heat-conducting block lower baffle plate adopt heat-barrier material;
The aluminium that described heat-conducting block adopts thermal conductivity good or copper product.
Described syringe needle can be syringe needle, also can be dispensing needle head.
Advantage of the present invention is: single spraying head of the present invention just can realize the printing to material different temperatures, the control of printed material various temperature can be realized by heating rod and cooling fin, solve the technical barrier that the single shower nozzle of traditional 3D printer can only heat or can only cool, simplify the framework of shower nozzle, reduce cost.
Accompanying drawing explanation
Fig. 1 is the structural representation of the biological 3D printing head towards high/low temperature combination;
Fig. 2 is the structural representation of the biological 3D printing head shell body towards high/low temperature combination;
Fig. 3 is the structural representation that the biological 3D printing head combined towards high/low temperature removes the shell body of front side board;
Fig. 4 is the biological 3D printing head shell body cooling segment structural representation towards high/low temperature combination;
Fig. 5 is the structural representation of the biological 3D printing head removal shell body towards high/low temperature combination;
Fig. 6 is the full sectional view of the biological 3D printing head removal shell body towards high/low temperature combination;
Fig. 7 is the structural representation of the biological 3D printing head heat-conducting block overhead gage towards high/low temperature combination;
Fig. 8 is the biological 3D printing head heat radiating fin structure schematic diagram towards high/low temperature combination.
In figure: 1-shell body, 1.1-upper plate, 1.2-left plate, 1.3-front side board, 1.4-base plate, 1.5-right plate, 1.6-back side panel, 2-heat-conducting block overhead gage, 3-heat-conducting block, 4-cooling fin, 5-heat-conducting block lower baffle plate, 6-syringe needle, 7-spiral cover, 8-syringe, 9-heating rod, 10-fin, 11-fan.
Detailed description of the invention
Concrete structure of the present invention, operation principle and course of work content is further illustrated below in conjunction with accompanying drawing 1-8 and embodiment.
A kind of biological 3D towards high/low temperature combination prints spray and has heating and cooling device, can realize the accurate control of various temperature, shower nozzle comprises shell body 1, heat-conducting block 3, heating rod 9, cooling fin 4, fin 10, fan 11, syringe 8, heat-conducting block overhead gage 2, heat-conducting block lower baffle plate 5, spiral cover 7 and syringe needle 6; Described heat-conducting block 3 is arranged in shell body 1, and it is inner that described heating rod 9 is arranged on heat-conducting block 3; Described cooling fin 4 is arranged on heat-conducting block 3 outer surface; Described fin 10 to be arranged on shell body 1 and to contact with cooling fin 4; Described fan 11 is arranged on fin 10 surface; It is inner that described syringe 8 is arranged on heat-conducting block 3; Described heat-conducting block lower baffle plate 5 is arranged between heat-conducting block 3 lower surface and shell body 1; Described heat-conducting block overhead gage 2 is arranged between the upper surface of heat-conducting block 3 and shell body 1; Described spiral cover 7 is connected with syringe 8 by screw thread, for convenience detach; Described syringe needle 6 is arranged on bottom syringe 8.
Described shell body 1 is made up of upper plate 1.1, base plate 1.4, left plate 1.2, right plate 1.5, front side board 1.3 and back side panel 1.6, is connected between each block of plate by bolt; Described upper plate 1.1 has through hole, for installing with heat-conducting block overhead gage 2; Described base plate 1.4 has circular hole, for passing through of syringe needle 6; Described left plate 1.2 and right plate 1.5 have straight trough mouth, distributing for heat; Described back side panel 1.6 has square hole, for the installation of fin 10; Described front side board 1.3 upper left corner has circular hole, and for heating rod 9, the supply line with cooling fin 4 installs.
Described heating rod 9 quantity is even number, is distributed on heat-conducting block 3 inner, ensures homogeneous heating; The heat that described heating rod 9 produces passes to syringe 8 by heat-conducting block 3, heats the material in syringe 8.
Described fin 10 one side fully contacts with the surface of cooling fin 4, and another side fully contacts with fan 11; Described cooling fin 4 siphons away the heat of material in syringe 8 by heat-conducting block 3 and passes to fin 10, then is discharged by heat by fan 11 turning effort, cools material.
Described heat-conducting block 3 does not contact with back side panel 1.6 with left plate 1.2, right plate 1.5, front side board 1.3, for heat insulation;
Described heat-conducting block overhead gage 2 and heat-conducting block lower baffle plate 5 adopt heat-barrier material; All can use as long as common heat-barrier material is applicable to structure of the present invention.
The aluminium that described heat-conducting block 3 adopts thermal conductivity good or copper product.
Described syringe needle 6 can be syringe needle, also can be dispensing needle head.
Operation principle of the present invention:
Before printing, according to the demand printing tissue, determine the temperature of printed material, when material require carries out adding hot print, be energized to heating rod 9, by heat-conducting block 3, the heat that heating rod 9 produces passed to barrel 8, material in barrel 8 is heated; When material require cools, be energized to cooling fin 4 and fan 11, in barrel 8, the heat of material passes to cooling piece by heat-conducting block 3, and is discharged by heat by fin 10 and fan 11, thus realizes material and cool.After reaching temperature requirement, booster air pump, inputs syringe 8 by gas by spiral cover 7, extrudes printing by syringe 8 pairs of materials.
Claims (8)
1. the biological 3D printing head towards high/low temperature combination, it is characterized in that shower nozzle has heating and cooling device, can realize the accurate control of various temperature, shower nozzle comprises shell body (1), heat-conducting block (3), heating rod (9), cooling fin (4), fin (10), fan (11), syringe (8), heat-conducting block overhead gage (2), heat-conducting block lower baffle plate (5), spiral cover (7) and syringe needle (6); Described heat-conducting block (3) is arranged in shell body (1), and it is inner that described heating rod (9) is arranged on heat-conducting block (3); Described cooling fin (4) is arranged on heat-conducting block (3) outer surface; Described fin (10) is arranged on shell body (1) and goes up and contact with cooling fin (4); Described fan (11) is arranged on fin (10) surface; It is inner that described syringe (8) is arranged on heat-conducting block (3); Described heat-conducting block lower baffle plate (5) is arranged between heat-conducting block (3) lower surface and shell body (1); Described heat-conducting block overhead gage (2) is arranged between the upper surface of heat-conducting block (3) and shell body (1); Described spiral cover (7) is connected with syringe (8) by screw thread, for convenience detach; Described syringe needle (6) is arranged on syringe (8) bottom.
2. as claimed in claim 1 a kind of towards high/low temperature combination biological 3D printing head, it is characterized in that: described shell body (1) is made up of upper plate (1.1), base plate (1.4), left plate (1.2), right plate (1.5), front side board (1.3) and back side panel (1.6), is connected between each block of plate by bolt; Described upper plate (1.1) has through hole, for installing with heat-conducting block overhead gage (2); Described base plate (1.4) has circular hole, for passing through of syringe needle (6); Described left plate (1.2) and right plate (1.5) have straight trough mouth, distributing for heat; Described back side panel (1.6) has square hole, for the installation of fin (10); Described front side board (1.3) upper left corner has circular hole, and for heating rod (9), the supply line with cooling fin (4) installs.
3. a kind of biological 3D printing head towards high/low temperature combination as claimed in claim 1, is characterized in that: described heating rod (9) quantity is even number, is distributed on heat-conducting block (3) inner, ensure homogeneous heating; The heat that described heating rod (9) produces passes to syringe (8) by heat-conducting block (3), heats the material in syringe (8).
4. as claimed in claim 1 a kind of towards high/low temperature combination biological 3D printing head, it is characterized in that: described fin (10) one side fully contact with the surface of cooling fin (4), another side fully contacts with fan (11); Described cooling fin (4) siphons away the heat of syringe (8) interior material by heat-conducting block (3) and passes to fin (10), then is discharged by heat by fan (11) turning effort, cools material.
5. as claimed in claim 2 a kind of towards high/low temperature combination biological 3D printing head, it is characterized in that: described heat-conducting block (3) does not contact with back side panel (1.6), for heat insulation with left plate (1.2), right plate (1.5), front side board (1.3).
6. as claimed in claim 1 a kind of towards high/low temperature combination biological 3D printing head, it is characterized in that: described heat-conducting block overhead gage (2) and heat-conducting block lower baffle plate (5) employing heat-barrier material.
7. a kind of biological 3D printing head towards high/low temperature combination as claimed in claim 1, is characterized in that: described heat-conducting block (3) adopts the good aluminium of thermal conductivity or copper product.
8. as claimed in claim 1 a kind of towards high/low temperature combination biological 3D printing head, it is characterized in that: described syringe needle (6) can be syringe needle, also can be dispensing needle head.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510353283.2A CN104985814B (en) | 2015-06-25 | 2015-06-25 | A kind of biological 3D printing shower nozzle combined towards high/low temperature |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510353283.2A CN104985814B (en) | 2015-06-25 | 2015-06-25 | A kind of biological 3D printing shower nozzle combined towards high/low temperature |
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| CN104985814A true CN104985814A (en) | 2015-10-21 |
| CN104985814B CN104985814B (en) | 2017-07-11 |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105538715A (en) * | 2016-01-05 | 2016-05-04 | 杭州捷诺飞生物科技有限公司 | High-temperature printing spray head and 3D printing equipment applying same |
| CN105963049A (en) * | 2016-04-20 | 2016-09-28 | 清华大学深圳研究生院 | Intelligent biological printing extruding system capable of realizing real-time and infinitely-variable-speed regulation on extrusion amount |
| CN108127911A (en) * | 2017-11-16 | 2018-06-08 | 杭州捷诺飞生物科技股份有限公司 | The biological 3D printing nozzle and method of self-defined subregion temperature control |
| CN109203701A (en) * | 2018-08-13 | 2019-01-15 | 合肥海闻自动化设备有限公司 | A kind of constant-temperature heating system of digital printer spray head |
| CN109591290A (en) * | 2018-12-29 | 2019-04-09 | 浙江大学滨海产业技术研究院 | A kind of 3D printer syringe needle and printing surface positioning device and method |
| CN109906041A (en) * | 2016-11-01 | 2019-06-18 | 雀巢产品技术援助有限公司 | Food processing and correlation technique |
| CN110065235A (en) * | 2019-06-06 | 2019-07-30 | 浙江大学滨海产业技术研究院 | A kind of 3D printing head temperature control device and method |
| CN110139739A (en) * | 2017-02-10 | 2019-08-16 | 惠普发展公司，有限责任合伙企业 | Construct material molten |
| CN111357787A (en) * | 2020-04-01 | 2020-07-03 | 西京学院 | Cake pattern-mounting 3D printing system |
| CN112140544A (en) * | 2020-07-31 | 2020-12-29 | 西安交通大学 | Temperature control direct-writing spray head of biological printer |
| CN112891016A (en) * | 2021-01-18 | 2021-06-04 | 华中科技大学鄂州工业技术研究院 | Biological 3D of controllable temperature low temperature prints shower nozzle device |
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| CN104552956A (en) * | 2015-01-26 | 2015-04-29 | 杭州电子科技大学 | Clean easy-to-use biological material printing spray head |
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| CN203569103U (en) * | 2013-10-28 | 2014-04-30 | 清华大学深圳研究生院 | Temperature control type cell printing nozzle |
| CN103587119A (en) * | 2013-11-13 | 2014-02-19 | 清华大学深圳研究生院 | Three-dimensional biological material forming equipment and extrusion nozzles thereof |
| CN104552956A (en) * | 2015-01-26 | 2015-04-29 | 杭州电子科技大学 | Clean easy-to-use biological material printing spray head |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105538715A (en) * | 2016-01-05 | 2016-05-04 | 杭州捷诺飞生物科技有限公司 | High-temperature printing spray head and 3D printing equipment applying same |
| CN105963049A (en) * | 2016-04-20 | 2016-09-28 | 清华大学深圳研究生院 | Intelligent biological printing extruding system capable of realizing real-time and infinitely-variable-speed regulation on extrusion amount |
| CN109906041B (en) * | 2016-11-01 | 2022-11-04 | 雀巢产品有限公司 | Food processing system and related method |
| CN109906041A (en) * | 2016-11-01 | 2019-06-18 | 雀巢产品技术援助有限公司 | Food processing and correlation technique |
| US11638442B2 (en) | 2016-11-01 | 2023-05-02 | Societe Des Produits Nestle S.A. | Food processing system and associated method |
| CN110139739A (en) * | 2017-02-10 | 2019-08-16 | 惠普发展公司，有限责任合伙企业 | Construct material molten |
| CN108127911A (en) * | 2017-11-16 | 2018-06-08 | 杭州捷诺飞生物科技股份有限公司 | The biological 3D printing nozzle and method of self-defined subregion temperature control |
| CN109203701A (en) * | 2018-08-13 | 2019-01-15 | 合肥海闻自动化设备有限公司 | A kind of constant-temperature heating system of digital printer spray head |
| CN109591290A (en) * | 2018-12-29 | 2019-04-09 | 浙江大学滨海产业技术研究院 | A kind of 3D printer syringe needle and printing surface positioning device and method |
| CN110065235A (en) * | 2019-06-06 | 2019-07-30 | 浙江大学滨海产业技术研究院 | A kind of 3D printing head temperature control device and method |
| CN111357787A (en) * | 2020-04-01 | 2020-07-03 | 西京学院 | Cake pattern-mounting 3D printing system |
| CN112140544A (en) * | 2020-07-31 | 2020-12-29 | 西安交通大学 | Temperature control direct-writing spray head of biological printer |
| CN112891016A (en) * | 2021-01-18 | 2021-06-04 | 华中科技大学鄂州工业技术研究院 | Biological 3D of controllable temperature low temperature prints shower nozzle device |
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| CN104985814B (en) | 2017-07-11 |
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