CN104984385B - A kind of pre- stick of water soluble medical - Google Patents

A kind of pre- stick of water soluble medical Download PDF

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Publication number
CN104984385B
CN104984385B CN201510436651.XA CN201510436651A CN104984385B CN 104984385 B CN104984385 B CN 104984385B CN 201510436651 A CN201510436651 A CN 201510436651A CN 104984385 B CN104984385 B CN 104984385B
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China
Prior art keywords
parts
stick
water
polyglycereol
rosin ester
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CN201510436651.XA
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Chinese (zh)
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CN104984385A (en
Inventor
崔珊珊
邢玉萍
王兴琦
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Shandong Weishi Pharmaceutical Co ltd
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Shandong Vianor Biotech Co ltd
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Abstract

The present invention provide it is a kind of be applied to injury gained in sports, surprisingly pull to wait and wrap up dressing, a kind of pre- stick of water soluble medical.The effect of water-soluble pre- stick is sprayed on the pars affecta skin of patient, quickly forms a kind of ventilative thin layer mucous membrane, is easy to bandage during wrapping not slipped with skin close adhesion, it is not loose be easy to remove.A kind of pre- stick of water soluble medical is by aqueous solvent(A)Constituted with polyglycereol rosin ester two parts.A agent raw material is the aqueous solution containing a small amount of medicinal alcohol;B agent is polyglycereol rosin ester thick liquid.Have the advantage that:Water-soluble pre- stick using the spraying of nuisanceless carbon dioxide propellant, can rapid film formation, it is easy to use, it is pollution-free to bad border.

Description

A kind of pre- stick of water soluble medical
Technical field
The present invention relates to a kind of natural water-soluble pre- stick, specifically a kind of affected part for being sprayed at patient, favorably In skin and bandage organic adhesion and be easy to what is removed, the material of referred to as a kind of pre- stick of water soluble medical.
Background technology
At present, at home, outside for the fixation of trauma skin surface bandage water-soluble pre- stick is undiscovered and remembers Carry.The raw material based on polyglycereol rosin ester, the pre- stick of water-soluble bandage of exploitation will be opened for water-soluble pre- stick Open up a new field.Due to the pre- stick water as solvent of this research project, the raw material based on natural glycerin modified rosin ester, Auxiliary is antioxygen bactericide in the thymol extracted from the plants such as thyme, imparts natural, safe, the non-stimulated spy of pre- stick Property.Because raw material is based on cheap and high security, thus it succeed in developing will for injury gained in sports, unexpected unexpected damage such as pull New contribution is made in the fixation of bandage during the treatment of wound, meanwhile, the application of water-soluble pre- stick creates good warp for enterprise Benefit of helping and social benefit.
The content of the invention
Pulled it is an object of the invention to provide one kind for human muscle, when injury gained in sports is treated, bandage is fixed necessary A kind of water-soluble pre- stick.
The purpose of the present invention realizes that the pre- stick of water soluble medical is by the raw material of following weight proportion in the following manner It is made, 70-90 parts of deionized water, 5-10 parts of medicinal alcohol, 2-6 parts of polyglycereol rosin ester, thymol bactericide 0.05-0.20 Part, preparation method is as follows:Individual raw material is added in reactor by proportioning, stirring is opened, is heated to 75 DEG C -- 90 DEG C, heating stirring Homogeneous half an hour, it is finished product to be cooled to room temperature packaging.
The pre- stick of described water soluble medical, is to be prepared from the following raw materials in parts by weight, 75-85 parts of deionized water, doctor With 6-9 parts of alcohol, 3-5 parts of polyglycereol rosin ester, 0.08-0.18 parts of thymol bactericide.
The pre- stick of described water soluble medical, is to be prepared from the following raw materials in parts by weight, 80 parts of deionized water, medical wine Smart 7 parts, 4 parts of polyglycereol rosin ester, 0.15 part of thymol bactericide.
The excellent effect of the present invention is as follows:
Because polyglycerol rosin has certain emulsibility in itself, and contain multiple hydroxyls in molecule(—OH)And ether Chain(-O-)Group, it is water-soluble good, can be mixed to the aqueous solution of uniformity in any proportion with water.Polyglycereol The sticky feature group contained in rosin ester molecule, can be with the hydroxyl on gauze and skin(-0H)With amino (- NH2) formation Faint hydrogen bond and realize bonding.Because pre- stick is that moisture on the aqueous solution, skin is easily locked without volatile, so not Length is stopped by gauze to be all easy to remove.
Raw material aqueous solvent in formula, medical glycerine, polyglycereol rosin ester are natural, inexpensive, and raw material is easy to get.
Preservative in formula is thymol, is the thymol solution extracted from natural thyme, frequently as external application One kind of bactericide, with medical value.With very strong bactericidal action and very strong acaricidal action, effect is rapid reliable.
Make solvent with alcohol water blend, wrap up pre-bonding when being treated applied to patient's local damage, pre- stick being had in itself Some bioaffinities, it is nontoxic to skin, non-stimulated and with certain protective effect.
Pre- stick function admirable, it is easy to use, after spraying can effectively, a thin layer of glue is promptly formed on skin Film, and the wrapping and adhesion of bandage are realized, thus it is pre- anti-slip and loose, and be easy to release and change.
The chemical stability of water-soluble pre- stick is good, and heat-resisting, cold tolerance is good, and physical property is good, there is enough glue Property, no volume contraction, rheology is small, is non-thermal, electric conductor.
Embodiment
Embodiment 1:
The pre- stick of water soluble medical is to be prepared from the following raw materials in parts by weight, 90 parts of deionized water, 10 parts of medicinal alcohol, 6 parts of polyglycereol rosin ester, 0.20 part of thymol bactericide:
Preparation method is as follows:Individual raw material is added in reactor by proportioning, stirring is opened, 75 DEG C -90 DEG C, heating are heated to Homogeneous half an hour is stirred, it is finished product to be cooled to room temperature packaging.
Embodiment 2
The pre- stick of water soluble medical is to be prepared from the following raw materials in parts by weight, 70 parts of deionized water, 5 parts of medicinal alcohol, 2 parts of polyglycereol rosin ester, 0.05 part of thymol bactericide.
Preparation method is same as Example 1.
Embodiment 3
The pre- stick of described water soluble medical, is to be prepared from the following raw materials in parts by weight, 75 parts of deionized water, medical wine Smart 6 parts, 3 parts of polyglycereol rosin ester, 0.08 part of thymol bactericide.
Preparation method is same as Example 1.
Embodiment 4
The pre- stick of described water soluble medical, is to be prepared from the following raw materials in parts by weight, 85 parts of deionized water, medical wine Smart 9 parts, 5 parts of polyglycereol rosin ester, 0.18 part of thymol bactericide.
Preparation method is same as Example 1.
Embodiment 5
The pre- stick of described water soluble medical, is to be prepared from the following raw materials in parts by weight, 80 parts of deionized water, medical wine Smart 7 parts, 4 parts of polyglycereol rosin ester, 0.15 part of thymol bactericide.
Preparation method is same as Example 1.
This water soluble medical pre-bonding agent producing process is relatively simple, and the key of technical process is polyglycereol rosin ester in water Dissolving.
Embodiment 6
The pre- stick of water soluble medical is sprayed on pars affecta skin when using, then wrapped up using bandage, bandage i.e. with Skin is brought into close contact, and is difficult to slip, convenient to be applicable, with safety, it is natural, efficiently, biological property is good the characteristics of.The pre- stick Succeed in developing, and the application in wound auxiliary treatment rehabilitation, it will the security of increase wound wrapping and the pre- stick of reduction Cost, the physiotherapy and rehabilitation for injury gained in sports and accident trauma is made new contribution, at the same create good economic benefit and Social benefit.
It is the known technology of those skilled in the art in addition to the technical characteristic described in specification.

Claims (3)

1. a kind of pre- stick of water soluble medical, it is characterised in that be to be prepared from the following raw materials in parts by weight, deionized water 70-90 Part, 5-10 parts of medicinal alcohol, 2-6 parts of polyglycereol rosin ester, 0.05-0.20 parts of thymol bactericide, preparation method is as follows:Will be each Raw material is added in reactor by proportioning, is opened stirring, is heated to 75 DEG C -- 90 DEG C, heating stirring homogeneous half an hour, it is cooled to room Thermometer bulb dress is finished product.
2. the pre- stick of water soluble medical according to claim 1, it is characterised in that be by the raw material system of following weight proportion Into 75-85 parts of deionized water, 6-9 parts of medicinal alcohol, 3-5 parts of polyglycereol rosin ester, 0.08-0.18 parts of thymol bactericide.
3. the pre- stick of water soluble medical according to claim 1, it is characterised in that be by the raw material system of following weight proportion Into 80 parts of deionized water, 7 parts of medicinal alcohol, 4 parts of polyglycereol rosin ester, 0.15 part of thymol bactericide.
CN201510436651.XA 2015-07-23 2015-07-23 A kind of pre- stick of water soluble medical Active CN104984385B (en)

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CN104984385B true CN104984385B (en) 2017-08-29

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107441168A (en) * 2017-09-27 2017-12-08 山东维赫生物科技有限公司 Compound peppermint is unsting hydrogel plaster

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2073758A (en) * 1978-10-30 1981-10-21 Kendall & Co Pressure-sensitive adhesives
CN1308537A (en) * 1998-07-10 2001-08-15 久光制药株式会社 Steroid-containing cataplasms and process for producing the same
CN1946429A (en) * 2004-04-28 2007-04-11 久光制药株式会社 Adhesive material

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005445A2 (en) * 1999-07-19 2001-01-25 Coloplast A/S A carbon dioxide generating device for medical treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2073758A (en) * 1978-10-30 1981-10-21 Kendall & Co Pressure-sensitive adhesives
CN1308537A (en) * 1998-07-10 2001-08-15 久光制药株式会社 Steroid-containing cataplasms and process for producing the same
CN1946429A (en) * 2004-04-28 2007-04-11 久光制药株式会社 Adhesive material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"马来松香聚甘油酯的合成及性能研究";王百军等;《日用化学工业》;20030430;第33卷(第2期);84-86 *

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Inventor after: Shi Shaojun

Inventor after: Cui Shanshan

Inventor after: Xing Yuping

Inventor after: Wang Xingqi

Inventor before: Cui Shanshan

Inventor before: Xing Yuping

Inventor before: Wang Xingqi

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20221116

Address after: 276000 southwest of the intersection of Xiangyu road and Xiamen Road, Zhimadun street, Linyi Economic Development Zone, Shandong Province

Patentee after: Shandong Weishi Pharmaceutical Co.,Ltd.

Address before: 276017 Floor 2, Block D, Innovation Building, Keji Avenue, High tech Zone, Linyi City, Shandong Province

Patentee before: SHANDONG VIANOR BIOTECH CO.,LTD.