CN102166370A

CN102166370A - Woundplast and preparation technology thereof

Info

Publication number: CN102166370A
Application number: CN2010105630288A
Authority: CN
Inventors: 吴克
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-11-29
Filing date: 2010-11-29
Publication date: 2011-08-31

Abstract

The invention discloses a woundplast and a preparation technology thereof. The woundplast consists of non-woven fabric, a hydrogel layer and a plastic film. The hydrogel layer comprises the raw materials based on weight percentage: 1%-5% of chitosan, 1%-5% of low-polymerized isomaltose, 1%-3% of peppermint oil, 1%-3% of p-hydroxybenzoic acid, 10%-30% of glycerol, 3%-8% of polyvinylpyrrolidone, 3%-8% of polyacrylic acid and 55%-75% of purified water. The prepared hydrogel layer, non-woven fabric and plastic film are coated and cut on a hydrogel coating machine set and are dried for 24h till that the moisture content is within the range from 50% to 65% so as to prepare the woundplast. The woundplast has the characteristics that the wound can be promoted to be healed, and the woundplast is flexible in use.

Description

Protecting wound applies ointment or plaster and preparation technology

Technical field

The present invention relates to medical instruments field, be specifically related to protect wound and apply ointment or plaster and preparation technology.

Background technology

Product such as bandage are created in common protecting on the existing market, generally be to adopt medical adhesive tape or the PU film that scribbles medical glue sticks on the wound surface place, when changing bandage, all can exist difficulty to tear at every turn, situation such as may also the wound that is healing can be torn once more, bring misery to the patient.

Summary of the invention

The objective of the invention is to the defective at traditional bandage, develop the adhesion wound, the wound of protecting of easily openable and difficult drop-off is applied ointment or plaster.

The wound of protecting of the present invention is applied ointment or plaster, form by non-woven fabrics, hydrogel layer and plastic film, wherein, by weight percentage, hydrogel layer is by 1%～5% chitosan, and 1%～5% oligomeric isomaltose, 1%～3% Oleum menthae, 1%～3% P-hydroxybenzoic acid, 10%～30% glycerol, 3%～8% polyvinylpyrrolidone, 3%～8% polyacrylic acid and 55%～75% purified water are formed.

A kind ofly prepare the described wound technology of applying ointment or plaster of protecting, concrete steps are:

1) Oleum menthae is added in the glycerol mixing, standby;

2) purified water is heated to 90 ℃, is incubated after 30 minutes, add P-hydroxybenzoic acid;

3) through step 2) when the material handled is cooled to 40 ℃, add polyvinylpyrrolidone, polyacrylic acid, fully dispersed with stirring is even;

4) mixture after step 3) is handled is lowered the temperature, add chitosan, oligomeric isomaltose and pre-dispersed material, fully mix, promptly get hydrogel layer;

5), on hydrogel coating unit, be coated with shearing with hydrogel layer, non-woven fabrics, plastic film;

6) the wound of protecting that will be after step 5) is sheared is applied ointment or plaster and is dried in the air 24 hours, to water content be between the 50-65%, can pack to such an extent that protect wound and apply ointment or plaster.

Beneficial effect: the wound of protecting of the present invention is applied ointment or plaster and is aquogel system, with skin the extraordinary compatibility and safety is arranged, and sticks on wound surface, provides a moistening growing environment to wound surface, helps the reparation of wound surface.In addition, chitosan is the product of chitin behind deacetylation, itself has a certain amount of electric charge, stick when wound surface, be adsorbed in the wound surface surface, wound surface and extraneous antibacterial are isolated, stop the pathogenic bacterium field planting from face, promote blood coagulation, thereby accelerate the reparation of wound surface.

The specific embodiment

Embodiment 1

The wound of protecting of the present invention is applied ointment or plaster, form by non-woven fabrics, hydrogel layer and plastic film, wherein, by weight percentage, hydrogel layer is made up of 2% chitosan, 2% oligomeric isomaltose, 0.5% Oleum menthae, 0.5% P-hydroxybenzoic acid, 20% glycerol, 5% polyvinylpyrrolidone, 5% polyacrylic acid and 65% purified water.

Protect the preparation technology that wound is applied ointment or plaster, concrete steps are:

1) the 5g Oleum menthae is added in the 200g glycerol mixing, standby;

2) the 650ml purified water is heated to 90 ℃, is incubated after 30 minutes, add the 5g P-hydroxybenzoic acid;

3) through step 2) when the material handled is cooled to 40 ℃, add 50g polyvinylpyrrolidone, 50g polyacrylic acid, fully dispersed with stirring is even;

4) mixture after step 3) is handled is lowered the temperature, add 20g chitosan, 20g oligomeric isomaltose and pre-dispersed material, fully mix, promptly get hydrogel layer;

6) dried in the air 24 hours, contain between the 50%-65% to moisture content, pack to such an extent that protect wound and apply ointment or plaster.

Claims

1. protecting wound applies ointment or plaster, form by non-woven fabrics, hydrogel layer and plastic film, it is characterized in that, by weight percentage, hydrogel layer is by 1%～5% chitosan, and 1%～5% oligomeric isomaltose, 1%～3% Oleum menthae, 1%～3% P-hydroxybenzoic acid, 10%～30% glycerol, 3%～8% polyvinylpyrrolidone, 3%～8% polyacrylic acid and 55%～75% purified water are formed.

2. the wound of protecting according to claim 1 is applied ointment or plaster, it is characterized in that, described hydrogel layer components based on weight percentage, chitosan account for 2%, oligomeric isomaltose accounts for 2%, Oleum menthae accounts for 0.5%, P-hydroxybenzoic acid accounts for 0.5%, glycerol accounts for 20%, polyvinylpyrrolidone accounts for 5%, polyacrylic acid accounts for 5%, purified water accounts for 65%.

3. one kind prepares the technology that wound is applied ointment or plaster of protecting as claimed in claim 1 or 2, it is characterized in that concrete steps are:

1) pre-dispersed: as Oleum menthae to be added in the glycerol mixing, standby;

2) with the purified water heating and after insulation a period of time, add P-hydroxybenzoic acid;

3) through step 2) when the material handled is cooled to uniform temperature, add polyvinylpyrrolidone, polyacrylic acid, fully dispersed with stirring is even;

4) after mixture that will be after step 3) is handled continues cooling, add chitosan, oligomeric isomaltose and pre-dispersed material, fully mix, promptly get hydrogel layer;

6) the wound of protecting that will be after step 5) is sheared is applied ointment or plaster and is dried in the air 24 hours, to water content be between the 50%-65%, promptly get hydrogel and protect to create and apply ointment or plaster.

4. the preparation technology that applies ointment or plaster of wound that protects according to claim 3 is characterized in that step 2) in the holding temperature that is heated to be 90 ℃, temperature retention time is 30 minutes.

5. according to claim 3 protecting created the preparation technology who applies ointment or plaster, and it is characterized in that the described uniform temperature that cools to of step 3) is 50 ℃.

6. according to claim 3 protecting created the preparation technology who applies ointment or plaster, and it is characterized in that in the step 4), the described temperature that cools to is 40 ℃.