CN107441168A - Compound peppermint is unsting hydrogel plaster - Google Patents

Compound peppermint is unsting hydrogel plaster Download PDF

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Publication number
CN107441168A
CN107441168A CN201710876743.9A CN201710876743A CN107441168A CN 107441168 A CN107441168 A CN 107441168A CN 201710876743 A CN201710876743 A CN 201710876743A CN 107441168 A CN107441168 A CN 107441168A
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China
Prior art keywords
oil
agent
hydrogel
unsting
parts
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CN201710876743.9A
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Chinese (zh)
Inventor
王兴琦
尚秀珍
杭玉琼
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Shandong Weihe Biotechnology Co Ltd
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Shandong Weihe Biotechnology Co Ltd
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Priority to CN201710876743.9A priority Critical patent/CN107441168A/en
Publication of CN107441168A publication Critical patent/CN107441168A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

Abstract

The present invention provides a kind of a kind of compound peppermint applied to the pain therapy such as ambition abdomen side of body rib, traumatic injury, dysmenorrhoea, rheumatic arthritis, varication and unsting hydrogel plaster, is to be prepared from the following raw materials in parts by weight:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9 10 parts of vitamin E;Water-soluble pre- 12 13 parts of stick;The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 75 85 parts of ethanol;Compound peppermint unstings hydrogel plaster with pure plant essential oil basic material, it is aided with water-soluble pre- stick, deionized water, NMF and water-soluble polyester as hydrogel plaster matrix components, can be compatible well with skin, it can be affixed at movable joint, it is difficult for drop-off, it is easy to remove, terminates administration at any time, Pure natural plant essential oil molecule is tiny, can be gone directly focus, uniform controlled release, high-efficient and lasting are fool proof to be also applied for children's heart chest and abdomen pain over the hypochondriac region, traumatic injury.

Description

Compound peppermint is unsting hydrogel plaster
Technical field
Unsting hydrogel plaster the present invention relates to a kind of compound peppermint, belong to medical ointment patch class field, specifically one It is kind easily peelable, patch can be taken off repeatedly, to stretch extension power strong, good compound peppermint is unsting hydrogel patch with the compatibility of skin.
Background technology
At present, the active ingredient in patch is mostly Chinese herbal medicine macromolecular, even if adding skin penetration enhancer, some big point Sub- medicine is also difficult to effectively be absorbed through skin barrier;And pure natural plants essential oil molecule is very tiny, pass through sebum Hole is absorbed up to dermal microvascular to blood, and by blood circulation and the through focus of Lymphatic Circulation, transdermal absorption factor is high, and drug effect is held Long;At home, water-soluble pre- stick, deionized water, NMF and water-soluble polyester are aided with pure plant essential oil basic material outside Compound peppermint as hydrogel plaster matrix components is unsting hydrogel plaster, impart compound peppermint unsting hydrogel plaster efficiently, day So, safe, non-stimulated characteristic, and undiscovered and record;The natural water-based gel rubber plaster of exploitation is water base hydrogel plaster, can It is compatible well with skin, patch can be taken off repeatedly, terminate administration, and essential oil molecule very little, Cutaneous permeation enhancing, uniformly control at any time Release, improve medicine effective rate of utilization;Because raw material is based on cheap and high security, so succeeding in developing for it will be ambition abdomen New contribution is made in the treatment of the pain such as side of body rib, traumatic injury, dysmenorrhoea, rheumatic arthritis, varication.
The content of the invention
It is bent to be used for ambition abdomen side of body rib, traumatic injury, dysmenorrhoea, rheumatic arthritis, vein it is an object of the invention to provide one kind A kind of compound peppermint of pain therapy is waited to unsting hydrogel plaster.
The purpose of the present invention realizes in the following manner, and the compound peppermint hydrogel plaster that unstings is by following weight proportion Raw material is made:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, vitamin E 9-10 parts;
(B)Agent:Water-soluble pre- stick 12-13 parts;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, ethanol 75-85 parts;
Preparation method is as follows:
(1)Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil is well mixed obtained(A)Agent;
(2)Appropriate amount of deionized water, ethanol are added into homogeneous in homogenizer to dissolve, then put into raw material polyglycereol rosin ester, heating To 75 DEG C -- 90 DEG C, stirring homogeneous obtains(B)Agent;
(3)Will(B)Agent is cooled to 45 DEG C -- 55 DEG C, adds(C)Agent, after stirring, add(A)Agent, stir under vacuum Mixing in 30 minutes forms cohesive hydrogel;
(4)Cohesive hydrogel is coated on spunlace non-woven cloth, hydrogel layer thickness is about 1.2mm, is covered with the anti-sticking rhombus of protection Isolated film piece is embossed, is cooled to room temperature, and uniformly cut, you can packaging.
Described compound peppermint is unsting hydrogel plaster, is to be prepared from the following raw materials in parts by weight:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9.3 parts of vitamin E;
(B)Agent:Water-soluble pre- 12.7 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol.
A kind of compound peppermint is unsting hydrogel plaster, and hydrogel matrix Main Ingredients and Appearance is water-soluble polyester, deionized water, NMF, water-soluble pre- stick.
A kind of compound peppermint is unsting hydrogel patch, and water-soluble polyester is the propylene pimarate of polyethylene glycol two.
A kind of compound peppermint is unsting hydrogel plaster, and NMF is vitamin E, is cooperateed with methyl nicotinate, strengthens essential oil Component for skin permeates, uniform controlled release, improves effective rate of utilization.
A kind of compound peppermint is unsting hydrogel plaster, and water-soluble pre- stick is appropriate amount of deionized water, ethanol and polyglycereol Made from rosin ester.
A kind of compound peppermint is unsting hydrogel plaster, its viscosity and affinity are moderate, peel off easily, moisture retention it is strong, can Take off repeatedly patch, stretching extension power it is strong, it is good with the compatibility of skin, can motion when use, and gently, do not stimulate skin.
A kind of compound peppermint is unsting hydrogel plaster, wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil and Chinese mugwort Sesame oil of receiving is natural plant essential oils, and essential oil molecule is small, is easy to skin and is absorbed into the through focus of the circulatory system.
A kind of compound peppermint is unsting hydrogel plaster, and dense menthol solutions are by polyoxyethylene sorbitan monoleate, menthol and 75% second What alcoholic solution was formulated.
The excellent effect of the present invention is as follows:
Compound peppermint unstings hydrogel plaster with pure plant essential oil basic material, is aided with water-soluble pre- stick, deionized water, NMF With water-soluble polyester as hydrogel plaster matrix components, there is efficient, natural, safe, non-stimulated characteristic;Due to this hydrogel Patch is water base hydrogel plaster, can be compatible well with skin, can be affixed at movable joint, difficult for drop-off, due to gel used Matrix is aqueous solution, and the moisture on skin is easily locked without volatile, no matter so residence time length can easily Remove, terminate administration at any time;Because pure natural plants essential oil molecule is very tiny, it is easy to absorbed by sebum hole and reach epidermis Capilary, by blood circulation and the through focus of Lymphatic Circulation, percutaneous permeability enhancing, uniform controlled release, improves medicine to blood Thing effective rate of utilization, lasting medicine;Because raw material is based on cheap and high security, so succeeding in developing for it will be ambition abdomen New contribution is made in the treatment of the pain such as side of body rib, traumatic injury, dysmenorrhoea, rheumatic arthritis, varication.
Wintergreen in formula can be promoted using the natural mate essential oil of supercritical fluid method extraction from holly leaf Enter blood circulation, there is the effect such as anti-inflammatory, antirheumatic, analgesic, alleviate rheumathritis pain, neuralgia, and other muscle It is uncomfortable with joint.
Cade oil in formula is to be contained from the needle juniper berry of northeast using the natural needle juniper essential oil of supercritical fluid method extraction There are monoterpene ketone, sequiterpene ketone, antibacterial draining toxin expelling, cure mainly arthritis, rheumatism, gout, sciatica, dysmenorrhoea etc..
Frankincense oil in formula is natural essential oil of the extraction from olibanum resin, has significant analgesia and bacteriostasis, cures mainly Epigastric pain, arthralgia pain due to rheumatism, traumatic injury, dysmenorrhoea, postpartum abdominal pain, smell delicate fragrance, aging skin is activated, makes us loosening and releives.
Eucalyptus oil camphor tree in formula is extracted from Luo Wensha leaves, there is the effect such as antiviral, antibacterial, analgesic, stimulating immune system, It is good muscle diastole agent and anodyne, is adapted to that treatment arthralgia, muscle be tight, myasthenia, it is very safe to skin, one The very safe essential oil of kind, it is adapted to anyone use, including children.
Patchouli oil in formula is the natural essential oil extracted from Pogostemon cablin grass, by rare sesquiterpene, Pogostemon cablin Alcohol and Pogostone composition, anti-inflammation, ease pain, remove dampness by means of aromatics, dampness removing except wind, polymerization wound promote it quickly to scab, can control Uncomfortable in chest, pained, rheumathritis pain, varication etc. are treated, while is a kind of good preservative.
Blumea oil in formula is from the natural essential oil of Blumea balsamifera aerial part extraction, and there is analgesic antiphlogistic, middle benefit gas to live The effect of blood, menstruation regulating, dispelling wind and eliminating dampness, the diseases such as swelling, arthralgia and myalgia, bruise knife wound and dysmenorrhoea are treated, and can cicatrized a wound Preventing from scar afterwards.
Raw material deionized water water, vitamin E, methyl nicotinate, ethanol, polyglycereol rosin ester, polyethylene glycol in formula Two propylene pimarates are natural, inexpensive, and raw material is easy to get.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Embodiment 1:
Described compound peppermint is unsting hydrogel plaster, is to be prepared from the following raw materials in parts by weight:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9.3 parts of vitamin E;
(B)Agent:Water-soluble pre- 12.7 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol;
Preparation method is as follows:
(1)Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil is well mixed obtained(A)Agent;
(2)Appropriate amount of deionized water, ethanol are added into homogeneous in homogenizer to dissolve, then put into raw material polyglycereol rosin ester, heating To 75 DEG C -- 90 DEG C, stirring homogeneous obtains(B)Agent;
(3)Will(B)Agent is cooled to 45 DEG C -- 55 DEG C, adds(C)Agent, after stirring, add(A)Agent, stir under vacuum Mixing in 30 minutes forms cohesive hydrogel;
(4)Cohesive hydrogel is coated on spunlace non-woven cloth, hydrogel layer thickness is about 1.2mm, is covered with the anti-sticking rhombus of protection Isolated film piece is embossed, is cooled to room temperature, and uniformly cut, you can packaging.
Embodiment 2:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9 parts of vitamin E;
(B)Agent:Water-soluble pre- 12 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 79 parts of ethanol;
Preparation method is same as Example 1.
Embodiment 3:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9 parts of vitamin E;
(B)Agent:Water-soluble pre- 13 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol;
Preparation method is same as Example 1.
Embodiment 4:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 10 parts of vitamin E;
(B)Agent:Water-soluble pre- 12 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol;
Preparation method is same as Example 1.
Embodiment 5:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 10 parts of vitamin E;
(B)Agent:Water-soluble pre- 13 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 77 parts of ethanol;
Preparation method is same as Example 1.
Embodiment 6:
(A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9.5 parts of vitamin E;
(B)Agent:Water-soluble pre- 12.5 parts of stick;
(C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol;
Preparation method is same as Example 1.
This compound peppermint is unsting, and hydrogel plaster production technology is relatively simple, and the key of technical process is that polyglycereol rosin ester exists Dissolving, the synthesis of the propylene pimarate of polyethylene glycol two and the preparation of dense menthol solutions in water.
The hydrogel plaster packaging bag of unstinging of compound peppermint is prolonged tearable mouth and torn during use, takes out paster, it is anti-sticking to throw off protection Rhombus is embossed isolated film piece, and gel face is attached into painful area, can be cut into appropriately sized use according to different painful areas, Also can be affixed at movable joint, it is difficult for drop-off, it is easy to use, there is efficient, natural, safe, non-stimulated characteristic;Compound peppermint The hydrogel plaster that unstings be it is water base, can be good with skin-friendliness, moisture on skin is easily locked without volatile, no matter stopping Stay time length to remove, terminate administration at any time;Pure natural plants essential oil molecule is very tiny in raw material, skin Permeability is strong, uniform controlled release, and medicine effective rate of utilization is high, lasting medicine;Used raw material is based on cheap and high security, institute The treatment for pain such as ambition abdomen side of body rib, traumatic injury, dysmenorrhoea, rheumatic arthritis, varication is done with succeeding in developing for it Go out new contribution, while create good economic benefit and social benefit.
It is the known technology of those skilled in the art in addition to the technical characteristic described in specification.

Claims (8)

  1. The hydrogel plaster 1. a kind of compound peppermint is unsting, it is characterised in that be to be prepared from the following raw materials in parts by weight:
    (A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, vitamin E 9-10 parts;
    (B)Agent:Water-soluble pre- stick 12-13 parts;
    (C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, ethanol 75-85 parts;
    Preparation method is as follows:
    (1)Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil is well mixed obtained(A)Agent;
    (2)Appropriate amount of deionized water, ethanol are added in homogeneous container and dissolved, raw material polyglycereol rosin ester is put into, is heated to 75 DEG C -- 90 DEG C, stirring homogeneous obtains(B)Agent;
    (3)Will(B)Agent is cooled to 45 DEG C -- 55 DEG C, adds(C)Agent, after stirring, add(A)Agent, stir under vacuum Mixing in 30 minutes forms cohesive hydrogel;
    (4)Cohesive hydrogel is coated on spunlace non-woven cloth, hydrogel layer thickness is about 1.2mm, is covered with the anti-sticking rhombus of protection Isolated film piece is embossed, is cooled to room temperature, and uniformly cut, you can packaging.
  2. 2. a kind of compound peppermint is unsting hydrogel plaster according to claim 1, it is characterised in that is by following weight proportion Raw material is made,
    (A)Agent:Wintergreen, cade oil, frankincense oil, eucalyptus oil camphor tree, patchouli oil, blumea oil, 9.3 parts of vitamin E;
    (B)Agent:Water-soluble pre- 12.7 parts of stick;
    (C)Agent:The propylene pimarate of polyethylene glycol two, dense menthol solutions, methyl nicotinate, deionized water, 78 parts of ethanol;
    According to claim 1, a kind of compound peppermint is unsting hydrogel plaster, it is characterised in that described hydrogel matrix is main Composition is water-soluble polyester, deionized water, NMF, water-soluble pre- stick.
  3. 3. unsting hydrogel plaster according to a kind of compound peppermint of claim 1,3, it is characterised in that described water-soluble polyester It is the propylene pimarate of polyethylene glycol two.
  4. 4. unsting hydrogel plaster according to a kind of compound peppermint of claim 1,3, it is characterised in that described NMF is dimension Raw plain E, is cooperateed with methyl nicotinate, is strengthened derived essential oil Cutaneous permeation, uniform controlled release, is improved effective rate of utilization.
  5. 5. unsting hydrogel plaster according to a kind of compound peppermint of claim 1,3, it is characterised in that described water-soluble pre-bonding Agent is made from appropriate amount of deionized water, ethanol and the reaction of polyglycereol rosin ester.
  6. 6. unsting hydrogel plaster according to a kind of peppermint of compound of claim 1,3, it is characterised in that the hydrogel plaster glues Degree and affinity it is moderate, peel off easily, moisture retention it is strong, can take off repeatedly patch, stretch extension power it is strong, it is good with the compatibility of skin, can With motion when use, and gently, do not stimulate skin.
  7. 7. a kind of compound peppermint is unsting hydrogel plaster according to claim 1, it is characterised in that wintergreen, cade oil, frankincense Oil, eucalyptus oil camphor tree, patchouli oil and blumea oil are natural plant essential oils, molecule very little, are easy to skin and absorb through focus.
  8. 8. a kind of compound peppermint is unsting hydrogel plaster according to claim 1, it is characterised in that the dense menthol solutions are It is formulated by polyoxyethylene sorbitan monoleate, menthol and 75% ethanol solution.
CN201710876743.9A 2017-09-27 2017-09-27 Compound peppermint is unsting hydrogel plaster Pending CN107441168A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569585A (en) * 2022-04-07 2022-06-03 四川省医学科学院·四川省人民医院 Application of patchouli alcohol in preparation of medicine for treating rheumatoid arthritis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202052060U (en) * 2010-12-30 2011-11-30 江西宜信堂医疗科技有限公司 Pain relieving patch
CN103919858A (en) * 2014-04-24 2014-07-16 江西中天医药生物有限公司 Externally applied drug applied tp acupuncture points to relieve swelling and pain and regulate endocrine, and preparation method thereof
CN104644785A (en) * 2015-02-03 2015-05-27 广东省中医院 Hydrophilic polymer gel layer and rhizoma chuanxiong-flos carthami meridian-activating plaster prepared by using same
CN104984385A (en) * 2015-07-23 2015-10-21 山东维赫生物科技有限公司 Water soluble medical pre-adhesive

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202052060U (en) * 2010-12-30 2011-11-30 江西宜信堂医疗科技有限公司 Pain relieving patch
CN103919858A (en) * 2014-04-24 2014-07-16 江西中天医药生物有限公司 Externally applied drug applied tp acupuncture points to relieve swelling and pain and regulate endocrine, and preparation method thereof
CN104644785A (en) * 2015-02-03 2015-05-27 广东省中医院 Hydrophilic polymer gel layer and rhizoma chuanxiong-flos carthami meridian-activating plaster prepared by using same
CN104984385A (en) * 2015-07-23 2015-10-21 山东维赫生物科技有限公司 Water soluble medical pre-adhesive

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李江英,等: "《现代中药制剂理论与实践》", 30 September 2016, 陕西科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569585A (en) * 2022-04-07 2022-06-03 四川省医学科学院·四川省人民医院 Application of patchouli alcohol in preparation of medicine for treating rheumatoid arthritis

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Application publication date: 20171208