CN104983994A - Preparing method for traditional Chinese medicine preparation for relieving irritable bowel syndrome - Google Patents
Preparing method for traditional Chinese medicine preparation for relieving irritable bowel syndrome Download PDFInfo
- Publication number
- CN104983994A CN104983994A CN201510470019.7A CN201510470019A CN104983994A CN 104983994 A CN104983994 A CN 104983994A CN 201510470019 A CN201510470019 A CN 201510470019A CN 104983994 A CN104983994 A CN 104983994A
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- chinese medicine
- bowel syndrome
- irritable bowel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a traditional Chinese medicine preparation for relieving the irritable bowel syndrome. The preparation is mainly prepared from, by weight, 3 parts of red halloysite, 6 parts of evodia rutaecarpa, 1.5 parts of pepper, 1.5 parts of concha arcae, 11 parts of radix puerariae, 10 parts of cyperus rotundus, 12 parts of poria, 11 parts of gordon euryale seed, 8 parts of nutgall, 18 parts of apple vinegar and 7 parts of sesame oil. The traditional Chinese preparation can rapidly relive the irritable bowel syndrome, the effective rate is 98 percent, the condition of the poor appetite of a patient can be relieved after the patient takes the medicine, the irritable bowel syndrome can be relieved for the patient, and the effects of strengthening the spleen and the stomach can also be achieved. Simple traditional Chinese medicine easy to obtain is adopted as the raw material of the traditional Chinese medicine preparation, effect taking is fast, no toxic or side effect exists, and the purpose of fast relieving the pain of the patient can be achieved.
Description
divisional application, original applying number 2014100479938, applying date 2014.2.12, title alleviates Chinese medicine preparation of irritable bowel syndrome and preparation method thereof.
Technical field
The invention discloses a kind of Chinese medicine preparation, especially a kind of Chinese medicine preparation alleviating irritable bowel syndrome and preparation method thereof.The invention belongs to traditional Chinese medicine field.
Background technology
Irritable bowel syndrome (IBS) is one group to be continued or interval outbreak, and to suffer from abdominal pain, abdominal distention, bowl evacuation habit and (or) stool change into clinical manifestation, and lack the function of intestinal canal disorder disease of gastrointestinal tract structure and biochemistry exception.Classical symptom is stomachache, the abdominal distention relevant to abnormal defecation, is divided into according to cardinal symptom: diarrhea predominance type; Constipation leading type; Alternating diarrhea and constipation type.The factors such as spirit, diet, cold can be lured symptom recurrence into or be increased the weight of.Irritable bowel syndrome (IBS) clinical manifestation is (1) stomachache.Be the cardinal symptom of IBS, with the exception of times of defecation or shape, suffer from abdominal pain and to alleviate more than after defecation, some patients easily occurs on the feed afterwards, and stomachache can betide any position of abdominal part, limitation or diffusivity, and characteristic of pain is various; (2) suffer from diarrhoea.1. persistence or intermittent diarrhea, excrement amount is few, in the pasty state, containing a large amount of mucus; 2. fasting transference cure after 72 hours; 3. do not occur night, be different from organic illness; 4. some patients can bring out because of feed; 5. patient can have diarrhoea and constipation Alternate Phenomenon; (3) constipation.Difficult defecation, constipation with dry stool, amount is few, and can be with more mucus, constipation can be interrupted or alternate with diarrhoea, and normal companion's defecation is felt not to the utmost; (4) abdominal distention.Daytime is heavier, especially in the afternoon, alleviates after nighttime sleep.
Irritable bowel syndrome causes with following reason: 1. gastrointestinal motility disorder: IBS patient's small intestinal interdigestive migrating motor complex is abnormal, cycle obviously shortens, there is more discrete contraction wave of gathering together in jejunum, and stomachache to send out majority in author relevant with it, these changes stress with sleep in more obvious.2. visceral paraesthesia: research finds that IBS most patients has and expands hypersensitive Clinical symptoms to tube chamber (rectum), its average pain threshold declines, uncomfortable degree after proctectasia strengthens or has abnormal internal organs-body radiating pain, and prompting spinal levels is to the exception of internal organs sensory signal process.3. Nervous and Mental Factors: psychological stress has appreciable impact to gastrointestinal function, it brings out IBS symptom, increase the weight of with ensured sustained development in play an important role, quite a few patient is with mental maladjustment, and wherein with anxiety, depression is main.4. intestinal infection: part IBS patient has intestinal infection history at premorbid, has part generation bowel dysfunction, has 10% can develop into and infect rear IBS in by various cause of disease (comprising antibacterial, virus, parasite) the gastroenteritis patient that infection causes.5. other: the symptom of part IBS patient is relevant with food, can increase the weight of its symptom, and the fiber fermentation in food may be too much gas Producing reason, and in addition, the disorder of intestinal microbial population may also be one of reason producing symptom.
In the method for existing alleviation irritable bowel syndrome, application publication number CN 102228550 A(application number 201110178870.4) disclose a kind of pharmaceutical composition for the treatment of irritable bowel syndrome, make composition and effectiveness primary raw material composition contained by this pharmaceutical composition for: Radix Bupleuri, Radix Paeoniae Alba (parched), Radix Saposhnikoviae, Fructus Aurantii Immaturus (parched), stir-fry Pericarpium Citri Reticulatae, Rhizoma Atractylodis Macrocephalae (parched), Fructus Mume, Rhizoma Coptidis, Radix Glycyrrhizae Preparata are made by crude drug.Application publication number CN 102379970 A(application number 201110336380.2) disclose a kind of Chinese medicine composition for the treatment of irritable bowel syndrome, this medicine consists of by weight, Radix Rehmanniae Preparata 100 parts, Semen Cuscutae 100 parts, Rhizoma Coptidis 60 parts, Radix Paeoniae 300 parts, Radix Saposhnikoviae 120 parts, Periostracum Cicadae 60 parts, Rhizoma Fagopyri Dibotryis 150 parts.Application publication number CN 103463417 A(application number 201310457174.6) disclose a kind of Chinese medicine for the treatment of irritable bowel syndrome, the medicament that the material medicine that it is made up of following weight proportion is made according to a conventional method: Radix Codonopsis 10-15g, Radix Astragali 12-20g, Rhizoma Atractylodis Macrocephalae 12-15g, Poria 12-15g, Rhizoma Dioscoreae 12-20g, Radix Bupleuri 10-12g, Radix Paeoniae Alba (parched) 15-20g, Radix Glycyrrhizae Preparata 6-10g, Rhizoma Corydalis 10-15g, Semen Lablab Album 12-20g, Radix Linderae 6-10g, Pericarpium Citri Reticulatae 12-15g.Though it is good to alleviate irritable bowel syndrome effect in patent existing at present, but its preparation method is complicated, and narrow application range, and be not suitable for child.
Summary of the invention
For the present situation of existing alleviation irritable bowel syndrome medicine deficiency, an object of the present invention is to provide a kind of Chinese medicine preparation alleviating irritable bowel syndrome, have and make simply, action effect is obvious, the feature such as applied widely, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine preparation.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine preparation alleviating irritable bowel syndrome, take off the primary raw material stating weight proportion to be prepared from: Halloysitum Rubrum 2-6 part, Fructus Evodiae 4-10 part, Fructus Piperis 1-3 part, Concha Arcae 1-3 part, Radix Puerariae 9-15 part, Rhizoma Cyperi 6-15 part, Poria 8-16 part, Semen Euryales 8-15 part, Galla Turcica (Galla Helepensis) 6-12 part, apple vinegar 14-26 part, Oleum Sesami 5-12 part.
Foregoing Chinese medicine preparation, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Halloysitum Rubrum 3-5 part, Fructus Evodiae 6-8 part, Fructus Piperis 1.5-2.5 part, Concha Arcae 1.5-2.5 part, Radix Puerariae 11-13 part, Rhizoma Cyperi 10-12 part, Poria 12-14 part, Semen Euryales 11-13 part, Galla Turcica (Galla Helepensis) 8-10 part, apple vinegar 18-22 part, Oleum Sesami 7-9 part.
Foregoing Chinese medicine preparation, better preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Halloysitum Rubrum 4 parts, Fructus Evodiae 7 parts, 2 parts, Fructus Piperis, Concha Arcae 2 parts, Radix Puerariae 12 parts, Rhizoma Cyperi 11 parts, Poria 13 parts, Semen Euryales 12 parts, Galla Turcica (Galla Helepensis) 9 parts, apple vinegar 20 parts, 8 parts, Oleum Sesami.
According to the preparation method of arbitrary described Chinese medicine preparation above, preferred scheme is that step is as follows:
4, according to the preparation method of the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, step is as follows:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire is fried 8-15 minute, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 90-120 mesh sieve, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 80-100 mesh sieve, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 45 C-65 DEG C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami be the 0.3-0.7 of medicamental pulverata consumption doubly.
Foregoing preparation method, preferred scheme is, step 1. slow fire fries 10-13 minute (preferably 12 minutes).
Foregoing preparation method, preferred scheme is, 1. step crosses 90-110 mesh sieve (preferably 100 mesh sieves).
Foregoing preparation method, preferred scheme is, 2. step crosses 85-95 mesh sieve (preferably 90 mesh sieves).
Foregoing preparation method, preferred scheme is, 3. step dries in the air to temperature 50 C-60 DEG C (preferably 55 DEG C).
Foregoing preparation method, preferred scheme is, the consumption of step 4. Oleum Sesami be the 0.4-0.6 of medicamental pulverata consumption doubly (preferably 0.5 times).
Present invention also offers the application of described Chinese medicine preparation when preparing the medicine for the treatment of functional diarrhea, infantile diarrhea and chronic diarrhea.
Using method: for making Chinese medicine preparation of the present invention reach optimum therapeuticing effect, oral medicine 2 times on the one, took one hour ante cibum of morning and evening, and medicine for external use 1 time on the one, gets 5-8g at every turn, was placed on adhesive plaster and was attached to SHENQUE acupoint 6 hours.
This Chinese medicine preparation is applicable to the patient of each age group, interiorly all can play the effect of rapid recovery irritable bowel syndrome with medicine for external use, therefore use inside and outside can selecting according to practical situation simultaneously or select one to use, and suitably can increase and decrease dose according to patient age, more flexible on application method.
Alleviate a Chinese medicine preparation for irritable bowel syndrome, the pharmacological effect of each crude drug is respectively:
Halloysitum Rubrum: have another name called red symbol, red Gao Ling, HALLOYSITUM RUBRUM is finely divided many mineral aggregates that silicates halloysite race Ore halloysite forms jointly with oxide-based bloodstone or hydrogeneous oxide-based limonite.The property of medicine: this product is block aggregation, in light red, red to aubergine, or red and white in textured, body is comparatively light, and matter is soft, and water absorbing capacity is strong, and micro-have clay gas, sweet in the mouth, puckery, and property is put down.Composition: main component is aluminium silicate hydrate, also containing trace element such as titanium, nickel, strontium, barium.Find according to modern pharmacological research, this medical instrument has effect of relieving diarrhea with astringent, hemostasis, removing dampness sore, for chronic diarrhea chronic dysentery, has blood in stool, and skin ulcer wound is burst for a long time and do not held back, eczema etc.
Fructus Evodiae: nature and flavor: pungent, bitter, heat; Slightly poisonous.Gui Jing: return liver, spleen, stomach, kidney channel.Effect: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang alleviation irritable bowel syndrome.Cure mainly: for sun headache of fainting, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea; External treatment aphtha, hypertension.
Fructus Piperis: acrid in the mouth, hot in nature.Effect: warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.Cure mainly: gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration.
Concha Arcae: have another name called Carnis Arca inflata shell, watt room, blood clam skin, row of tiles on a roof clam skin, for Carnis Arca inflata section Carnis Arca inflata belongs to the shell that animal Scapharca subcrenata, Scapharca broughtonii and Tegillarca granosa belong to animal Tegillarca granosa.The property of medicine: matter is hard, sweet in the mouth, salty, property is put down.Composition: main component is calcium carbonate, also containing a small amount of calcium phosphate and magnesium, ferrum, silicate.Find according to modern pharmacological research, this medical instrument has effect of expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache, for pertinacious phlegm chronic cough, and stomachache acid regurgitation, traumatic hemorrhage, gastric and duodenal ulcers.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, and yang invigorating alleviates irritable bowel syndrome.Cure mainly: fever caused by exogenous pathogens is had a headache, and thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels.
Rhizoma Cyperi: nature and flavor: pungent, micro-hardship, micro-sweet, flat.Gui Jing: return liver, spleen, tri-jiao channel.Effect: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Cure mainly: for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Poria: Poria, is the sclerotium of On Polyporaceae Poria, comes from Shennong's Herbal, be commonly called as Poria, Song Ling, Poria, for colonizing in the fungi plant on pinaster root, promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieves internal heat anticancer.Mild in medicine property and, dampness removing and do not hinder healthy energy.Take in right amount can be used as spring and summer wet season take good care of good merchantable brand, dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis can be controlled, have loose bowels, pass out semen, stranguria with turbid discharge, palpitation with fear, the disease such as forgetful.Contained pachymic acid has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc.Can be relaxed gastrointestinal smooth muscle, the effects such as gastric acid secretion inhibiting, prevents hepatic necrosis, antibacterial
Semen Euryales: sweet in the mouth, puckery, property is put down.Effect: supplementing the kidney to control the nocturnal, irritable bowel syndrome is alleviated in spleen reinforcing, damp eliminating leukorrhagia stopping.Cure mainly: emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Galla Turcica (Galla Helepensis): have another name called black stone, without infanticide, the parasitized larvae belonging to insecticide gall wasps for gall wasps section cynipid sets the insect gall that sprout produces in Fagaceae oak plant Galla Turcica (Galla Helepensis).The property of medicine: this product is spherical in shape, has short handle, and outer surface Lycoperdon polymorphum Vitt has verruca, and matter heavily fortified point is thick, and bitter in the mouth is warm in nature.Composition: Galla Turcica (Galla Helepensis) insect gall is containing turkish gallotannin, gallic acid and resin etc.Find according to modern pharmacological research, this medical instrument have astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, astringe the lung, effect of hemostasis and pain-relieving, for chronic diarrhea chronic dysentery, night sweat, cough, spitting of blood, has blood in stool.
Apple vinegar: with the Fructus Mali pumilae former vinegar of Sucus Mali pumilae through fermentation, the pectin wherein contained is conducive to the growth of probiotics in intestinal, sour in the mouth, sweet.
Oleum Sesami: English name OLEUM SESAMI.Base is former: this product is the fatty oil that the mature seed milling process of Pedaliaceae plant sesame obtains.Purposes: lubricant and excipient, for oral administration can intestine moistening, lung moistening; Be used as ointment machin plaster substrate (Oleum Sesami used in the present invention is extracted by Semen Sesami) outward.
Chinese medicine preparation of the present invention alleviates the principle of irritable bowel syndrome based on Chinese medicine, the Chinese medicinal material selected all has the effect alleviating irritable bowel syndrome, spleen invigorating, stomach function regulating, and oral medicine taste is sour-sweet, avoids the embarrassment of good medicine tastes bitter, this Chinese medicine preparation compatibility is proper, is applicable to the patient of each age group.
Compared with prior art, its technique effect is embodied in the present invention:
(1) extraction process is simple, and extraction efficiency is high, energy consumption and loss little, cost is low;
(2) add nutritional labeling and active ingredient, but do not change the curative effect that each crude drug cooperatively interacts;
(3) long-term taking this product has special efficacy to irritable bowel syndrome, chronic diarrhea, functional diarrhea, more can improve immunity.
Accompanying drawing explanation
Fig. 1 is that after taking prescription of the present invention, constipation or symptom of diarrhea obviously improve or Disappearance Scenarios design sketch;
Fig. 2 takes appetite recovery situation design sketch after prescription of the present invention.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1alleviate a Chinese medicine preparation for irritable bowel syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Halloysitum Rubrum 2 parts, Fructus Evodiae 4 parts, 1 part, Fructus Piperis, Concha Arcae 1 part, Radix Puerariae 9 parts, Rhizoma Cyperi 6 parts, Poria 8 parts, Semen Euryales 8 parts, Galla Turcica (Galla Helepensis) 6 parts, apple vinegar 14 parts, 5 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine preparation, step is:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire are fried 8 minutes, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 90 mesh sieves, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 80 mesh sieves, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 45 C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.3 times of medicamental pulverata consumption.
model case onefirst ××, man, 50 years old, on August 20th, 2011 went to a doctor.Suffer from abdominal pain, suffer from diarrhoea, rush down rear alleviation of pain, before half a year with abdominal distention, defecation not to the utmost, fecal urgency, anxiety etc., once took montmorillonite powder, FUFANG HUANGLIANSU PIAN, sharp spleen benefit intestinal ball etc., poor effect and examining.Doctor checks discovery: body of the tongue is light red, white and thin fur, moderate pulse, and stool routine examination and enteroscopy are all normal, examine as irritable bowel syndrome, gives and to take and with the use of the embodiment of the present invention 1 gained Chinese medicine preparation.
Use the embodiment of the present invention 1 gained Chinese medicine preparation, get medicine for external use 8g and be all affixed on patient's SHENQUE acupoint with being placed on adhesive plaster, after 5 hours, patient's symptom of diarrhea obviously alleviates, and after 12 hours, nothing is suffered from diarrhoea phenomenon.Supper is got oral medicine 25g for last hour and is drunk, and supper patient appetite in second day recovers normal, after meal also without diarrhoea phenomenon.
embodiment 2a kind of Chinese medicine preparation alleviating irritable bowel syndrome, take off the primary raw material stating weight proportion to be prepared from (getting 5g for every part): Halloysitum Rubrum 6 parts, Fructus Evodiae 10 parts, 3 parts, Fructus Piperis, Concha Arcae 3 parts, Radix Puerariae 15 parts, Rhizoma Cyperi 15 parts, Poria 16 parts, Semen Euryales 15 parts, Galla Turcica (Galla Helepensis) 12 parts, apple vinegar 26 parts, 12 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine preparation, step is:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire are fried 15 minutes, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 120 mesh sieves, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 100 mesh sieves, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 65 DEG C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.7 times of medicamental pulverata consumption.
embodiment 3a kind of Chinese medicine preparation alleviating irritable bowel syndrome, take off the primary raw material stating weight proportion to be prepared from (getting 15g for every part): Halloysitum Rubrum 3 parts, Fructus Evodiae 6 parts, 1.5 parts, Fructus Piperis, Concha Arcae 1.5 parts, Radix Puerariae 11 parts, Rhizoma Cyperi 10 parts, Poria 12 parts, Semen Euryales 11 parts, Galla Turcica (Galla Helepensis) 8 parts, apple vinegar 18 parts, 7 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine preparation, step is:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire are fried 10 minutes, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 95-115 mesh sieve, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 85 mesh sieves, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 50 C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.4 times of medicamental pulverata consumption.
embodiment 4a kind of Chinese medicine preparation alleviating irritable bowel syndrome, take off the primary raw material stating weight proportion to be prepared from (getting 20g for every part): Halloysitum Rubrum 5 parts, Fructus Evodiae 8 parts, 2.5 parts, Fructus Piperis, Concha Arcae 2.5 parts, Radix Puerariae 13 parts, Rhizoma Cyperi 12 parts, Poria 14 parts, Semen Euryales 13 parts, Galla Turcica (Galla Helepensis) 10 parts, apple vinegar 22 parts, 9 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine preparation, step is:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire are fried 13 minutes, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 115 mesh sieves, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 95 mesh sieves, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 60 C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.6 of medicamental pulverata consumption.
model case two, king's ××, female 15 years old, in October, 2012 examines.Suffer from abdominal pain, suffer from diarrhoea, rush down rear alleviation of pain, often increase the weight of existing 1 year because of emotional stimulation, once took the medicine such as levofloxacin tablet, JIECHANGYAN WAN and examine without obvious curative effects.Find patient through traditional Chinese medical science inspection: micro-greasy, the deep and stringy pulse of pale tongue, thin fur, stool routine examination and enteroscopy are all normal, examine as irritable bowel syndrome.To take and with the use of the embodiment of the present invention 4 gained Chinese medicine preparation.
Use the embodiment of the present invention 4 gained Chinese medicine preparation, get medicine for external use 5g and be all affixed on infant SHENQUE acupoint with being placed on adhesive plaster, after 6 hours, patient's symptom of diarrhea has and obviously alleviates, and pain of having a stomachache alleviates, and the phenomenon of abdominal distention disappears substantially.Supper is got oral medicine 20g for last hour and is drunk, and second day breakfast patient appetite is normal, and after meal also without diarrhoea phenomenon, the phenomenon of abdominal distention disappears.
embodiment 5a kind of Chinese medicine preparation alleviating irritable bowel syndrome, take off the primary raw material stating weight proportion to be prepared from (getting 30g for every part): Halloysitum Rubrum 4 parts, Fructus Evodiae 7 parts, 2 parts, Fructus Piperis, Concha Arcae 2 parts, Radix Puerariae 12 parts, Rhizoma Cyperi 11 parts, Poria 13 parts, Semen Euryales 12 parts, Galla Turcica (Galla Helepensis) 9 parts, apple vinegar 20 parts, 8 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine preparation, step is:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire is fried 8-15 minute, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 110 mesh sieves, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 90 mesh sieves, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 55 DEG C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.5 times of medicamental pulverata consumption.
experimental examplein order to verify that this Chinese medicine preparation alleviates the definite curative effect of irritable bowel syndrome, randomly draw to examine diarrhea patient 250 people (diet is not tied, diet is excessively cool, the irritable bowel syndrome that the mental status is not good etc. causes), the mean age is 28 years old, minimum 3 years old, maximum 55 years old.Be divided into administration group and matched group according to the state of an illness and pathology, often organize each 125 people, guarantee administration group and matched group situation basically identical, wherein irritable bowel syndrome patients 80 people in each group.
Administration group uses the embodiment of the present invention 5 gained Chinese medicine preparation every day, and for making Chinese medicine preparation of the present invention reach optimum therapeuticing effect, oral medicine 2 times on the one, one hour ante cibum of morning and evening.Medicine for external use 1 time on the one, gets 5-8g at every turn, is placed on adhesive plaster and is attached to SHENQUE acupoint 6 hours.Experimental group uses other medicines alleviating irritable bowel syndrome (as pinaverium bromide, XIELITING, intestinal paste the conventional medicines alleviating irritable bowel syndrome such as peaceful).Criterion: cure, malaise symptoms disappears; Effectively, malaise symptoms disappears substantially; Invalid, malaise symptoms is unchanged.
Observe 3 days time limits, observed content is as follows:
1, take medicine in 1-12 hour, observed once every 4 hours, record the number that disease is obviously alleviated, result is as accompanying drawing 1:
Analyze: as can be seen from accompanying drawing 1, though the present invention is Chinese medicine preparation, but it is substantially identical with other alleviation irritable bowel syndrome medicine classes to alleviate irritable bowel syndrome speed, substantially obviously can improve the symptom of diarrhea of patient, reach the object of rapid recovery patient suffering in 1-12 hour.
2, to abdominal distention in each group, stomachache with 80 patients of diarrhoea taking medicine in 3 days, getting 3 with meal (is first day dinner respectively, dinner in second day, and the dinner of the 3rd day) they are taken medicine after appetite recovery situation statistics and record, result is as accompanying drawing 2:
Analyze: as can be seen from accompanying drawing 2, Chinese medicine preparation of the present invention can make abdominal distention, stomachache with the patient of diarrhoea phenomenon, recover its appetite, for the continuation rehabilitation of patient and the absorption of nutrition are laid a good foundation taking medicine in the shorter time.
3, matched group is taken other and is alleviated irritable bowel syndrome medicines and experimental group and take Chinese medicine composition Comparison of therapeutic of the present invention, and result is as shown in table 1:
Table 1
Analyze: as can be seen from Table 1, take and use Chinese medicine composition effective percentage of the present invention up to 96%, cure rate is up to 92%, and successful is better than taking other alleviation irritable bowel syndrome medicines.
efficacy analysis:administration group (Chinese medicine preparation of the present invention) and matched group all can reach the object of rapid recovery irritable bowel syndrome in 3 days of the observation period, but in matched group diarrhoea and with vomiting phenomenon patient, the recovery of appetite is starkly lower than administration group after the tablet has been ingested.Prove through clinical trial, Chinese medicine preparation of the present invention can alleviate irritable bowel syndrome rapidly, and effective percentage is 96%, and can improve the situation that patient is off one's feed after taking medicine, and can not only alleviate irritable bowel syndrome, can also play effect of spleen-and-stomach-invigorating for patient.Chinese medicine preparation of the present invention adopts Chinese medicinal material simple and easy to get as raw material, instant effect, and without any side effects, the object alleviating rapidly patient's misery can be reached, do not tie diet, diet is excessively cool, the irritable bowel syndrome that the mental status is not good etc. causes has good therapeutical effect.
Claims (7)
1. alleviate the Chinese medicine preparation of irritable bowel syndrome, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Halloysitum Rubrum 3 parts, Fructus Evodiae 6 parts, 1.5 parts, Fructus Piperis, Concha Arcae 1.5 parts, Radix Puerariae 11 parts, Rhizoma Cyperi 10 parts, Poria 12 parts, Semen Euryales 11 parts, Galla Turcica (Galla Helepensis) 8 parts, apple vinegar 18 parts, 7 parts, Oleum Sesami.
2. the preparation method of Chinese medicine preparation according to claim 1, is characterized in that, step is as follows:
1. Fructus Evodiae, Radix Puerariae, Rhizoma Cyperi, Poria and Semen Euryales slow fire is fried 8-15 minute, air dry of drying in the air after stir-fry is extremely savory is done, and pulverizes 90-120 mesh sieve, and obtains medicamental pulverata for subsequent use;
2. by Halloysitum Rubrum, Concha Arcae, Fructus Piperis and Galla Turcica (Galla Helepensis) pulverization, cross 80-100 mesh sieve, obtain medicamental pulverata for subsequent use;
3. by step 1. in gained medicamental pulverata boiling water punching melt, wait to dry in the air to temperature 45 C-65 DEG C, add apple vinegar and stir, gained is oral medicine, and the weight proportion of three is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami be the 0.3-0.7 of medicamental pulverata consumption doubly.
3. preparation method according to claim 2, is characterized in that, step 1. slow fire fries 10-13 minute (preferably 12 minutes).
4. preparation method according to claim 2, is characterized in that, 1. step crosses 95-115 mesh sieve (preferably 110 mesh sieves).
5. preparation method according to claim 2, is characterized in that, 2. step crosses 85-95 mesh sieve (preferably 90 mesh sieves).
6. preparation method according to claim 2, is characterized in that, 3. step dries in the air to temperature 50 C-60 DEG C (preferably 55 DEG C).
7. preparation method according to claim 2, is characterized in that, the consumption of step 4. Oleum Sesami be the 0.4-0.6 of medicamental pulverata consumption doubly (preferably 0.5 times).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410047993.8A CN103784665B (en) | 2014-02-12 | 2014-02-12 | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410047993.8A Division CN103784665B (en) | 2014-02-12 | 2014-02-12 | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104983994A true CN104983994A (en) | 2015-10-21 |
Family
ID=50661002
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410047993.8A Expired - Fee Related CN103784665B (en) | 2014-02-12 | 2014-02-12 | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof |
| CN201510470098.1A Pending CN104983996A (en) | 2014-02-12 | 2014-02-12 | Traditional Chinese medicine for relieving irritable bowel syndrome |
| CN201510470019.7A Pending CN104983994A (en) | 2014-02-12 | 2014-02-12 | Preparing method for traditional Chinese medicine preparation for relieving irritable bowel syndrome |
| CN201510470045.XA Pending CN104983995A (en) | 2014-02-12 | 2014-02-12 | Medicine for treating irritable bowel syndrome |
| CN201510469976.8A Pending CN104983993A (en) | 2014-02-12 | 2014-02-12 | Chinese herba preparation for relieving irritable bowel syndrome |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410047993.8A Expired - Fee Related CN103784665B (en) | 2014-02-12 | 2014-02-12 | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof |
| CN201510470098.1A Pending CN104983996A (en) | 2014-02-12 | 2014-02-12 | Traditional Chinese medicine for relieving irritable bowel syndrome |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510470045.XA Pending CN104983995A (en) | 2014-02-12 | 2014-02-12 | Medicine for treating irritable bowel syndrome |
| CN201510469976.8A Pending CN104983993A (en) | 2014-02-12 | 2014-02-12 | Chinese herba preparation for relieving irritable bowel syndrome |
Country Status (1)
| Country | Link |
|---|---|
| CN (5) | CN103784665B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587036A (en) * | 2015-01-17 | 2015-05-06 | 张广庆 | Traditional Chinese medicine umbilicus application for treating irritable bowel syndrome of children |
| CN105535633A (en) * | 2016-01-19 | 2016-05-04 | 王保国 | Medicine for treating large intestine dryness-heat type irritable bowel syndrome |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188685A (en) * | 2011-04-27 | 2011-09-21 | 吴长岩 | Externally-applied traditional Chinese medicine powder for treating diarrhea type irritable bowel syndrome and preparation method thereof |
| CN102397372A (en) * | 2011-11-17 | 2012-04-04 | 云南云药科技股份有限公司 | Medicinal composition and pharmaceutical preparation and application thereof to treating irritable bowel syndrome |
| CN103463417A (en) * | 2013-09-30 | 2013-12-25 | 丰建君 | Traditional Chinese medicine used for treating irritable bowel syndrome |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1954881A (en) * | 2005-10-08 | 2007-05-02 | 刘国飞 | Chinese medicinal composite for treating intestinal irritable syndrome and its preparation method |
| CN101530580B (en) * | 2009-04-14 | 2011-09-07 | 路正平 | Drug for curing ulcerative colitis |
| KR101309967B1 (en) * | 2011-04-19 | 2013-09-27 | 주식회사 고암바이오알앤디수 | Pharmaceutical composition for treating or preventing fatty liver disease comprising extract of Cyperi Rhizoma |
| CN102846998A (en) * | 2011-06-27 | 2013-01-02 | 张红旗 | A Chinese medicinal formulation for treating chronic enteritis (due to diarrhea induced by spleen deficiency) |
| CN103349770B (en) * | 2013-07-24 | 2015-05-20 | 于红 | Traditional Chinese medicine composition for treating diarrhoea |
-
2014
- 2014-02-12 CN CN201410047993.8A patent/CN103784665B/en not_active Expired - Fee Related
- 2014-02-12 CN CN201510470098.1A patent/CN104983996A/en active Pending
- 2014-02-12 CN CN201510470019.7A patent/CN104983994A/en active Pending
- 2014-02-12 CN CN201510470045.XA patent/CN104983995A/en active Pending
- 2014-02-12 CN CN201510469976.8A patent/CN104983993A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188685A (en) * | 2011-04-27 | 2011-09-21 | 吴长岩 | Externally-applied traditional Chinese medicine powder for treating diarrhea type irritable bowel syndrome and preparation method thereof |
| CN102397372A (en) * | 2011-11-17 | 2012-04-04 | 云南云药科技股份有限公司 | Medicinal composition and pharmaceutical preparation and application thereof to treating irritable bowel syndrome |
| CN103463417A (en) * | 2013-09-30 | 2013-12-25 | 丰建君 | Traditional Chinese medicine used for treating irritable bowel syndrome |
Non-Patent Citations (2)
| Title |
|---|
| 范剑薇: "升阳益胃汤配合神阙穴贴敷治疗腹泻型肠易激综合征68例", 《辽宁中医杂志》 * |
| 陈震等: "肠激惹综合征(IBS)的研究进展", 《河北中医》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104983993A (en) | 2015-10-21 |
| CN104983995A (en) | 2015-10-21 |
| CN104983996A (en) | 2015-10-21 |
| CN103784665A (en) | 2014-05-14 |
| CN103784665B (en) | 2016-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106474418A (en) | For treating Chinese medicine composition of gastropathy and preparation method thereof | |
| CN105816788A (en) | Traditional Chinese medicine preparation for treating infantile dyspepsia and preparation method thereof | |
| CN100548367C (en) | A kind of Chinese medicine composition of took orally for treating chronic gastritis | |
| CN103386037B (en) | Traditional Chinese medicine for treating liver-stomach disharmony-caused reflux esophagitis | |
| CN101766787B (en) | Enema liquid for treating hyperpyrexia and cough and asthma | |
| CN101721667A (en) | Traditional Chinese medicine for treating indigestion | |
| CN103784665B (en) | Alleviate Chinese medicine preparation of irritable bowel syndrome and preparation method thereof | |
| CN103735779B (en) | Chinese medicinal formulae for the treatment of acute diarrhea and preparation method thereof | |
| CN102579787B (en) | Traditional Chinese medicine composition for treating chronic gastritis | |
| CN104906511A (en) | Traditional Chinese medicine preparation for reflux esophagitis and preparation method of traditional Chinese medicine preparation | |
| CN103830486A (en) | Traditional Chinese medicine for treating globus hysteriocus | |
| CN103784924B (en) | Chinese medicine composition of a kind of antidiarrheal and preparation method thereof | |
| CN105497677A (en) | Traditional Chinese medicine composition for promoting gastric disease rehabilitation | |
| CN103721157B (en) | A kind of Chinese medicine preparation for the treatment of functional dyspepsia | |
| CN103735794B (en) | Chinese medicine preparation for the treatment of vomiting and dirarrhea and preparation method thereof | |
| CN103961632A (en) | Traditional Chinese medicinal composition for treating gastric ulcer and duodenal ulcer | |
| CN103566351B (en) | Traditional Chinese medicine preparation for treating infantile diarrhea | |
| CN103860844A (en) | Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof | |
| CN103977156A (en) | Chinese medicine for treating intractable hiccup | |
| CN103690901A (en) | Traditional Chinese medicine for treating cholelithiasis and preparation method thereof | |
| CN104055901A (en) | Chinese herb preparation for treating functional dyspepsia and preparation method of Chinese herb preparation for treating functional dyspepsia | |
| CN107823585A (en) | A kind of endo-medicine and preparation method for being used to treat gastral cavity pain | |
| CN107551025A (en) | A kind of Chinese medicine composition for treating heart splenic hygropyrexia card aphtha and preparation method thereof | |
| CN105639424A (en) | Japonica rice powder for chronic rhinitis and preparation method of japonica rice powder | |
| CN106267097A (en) | A kind of for decoction medicine treating intractable singultus and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 336000, building No. 643, Zhongshan Middle Road, Yuanzhou District, Jiangxi, 1-402 Applicant after: Jiang Tao Address before: 250300 Shandong Province, Changqing District of Ji'nan city Dongliwalu No. 7 Applicant before: Jiang Tao |
|
| COR | Change of bibliographic data | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151021 |