CN103386037B - Traditional Chinese medicine for treating liver-stomach disharmony-caused reflux esophagitis - Google Patents

Traditional Chinese medicine for treating liver-stomach disharmony-caused reflux esophagitis Download PDF

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CN103386037B
CN103386037B CN201310305699.8A CN201310305699A CN103386037B CN 103386037 B CN103386037 B CN 103386037B CN 201310305699 A CN201310305699 A CN 201310305699A CN 103386037 B CN103386037 B CN 103386037B
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chinese medicine
reflux esophagitis
stomach
traditional chinese
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CN103386037A (en
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高贵伟
王加苹
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Haimen Jianghai Construction Investment Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine for treating liver-stomach disharmony-caused reflux esophagitis. The traditional Chinese medicine is prepared from cystopteris japonica luerss, root-bark of Japanese plum, rhizoma corydalis, orange peel, phoenix-tail fern, Bambusa sinospinosa Mc Clure, anise, magnolia cortex, pinellia ternate and mica. The traditional Chinese medicine can be used for treating liver-stomach disharmony-caused reflux esophagitis.

Description

A kind of Chinese medicine for the treatment of liver-stomach disharmony type reflux esophagitis
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of liver-stomach disharmony type reflux esophagitis.
Background technology
Reflux esophagitis (reflux esophagitis, RE) refers to and flows into a kind of chronic refractory disease that esophagus causes that Esophageal Mucosa damages because Stomach duodenum content is counter.Often belong to the categories such as the traditional Chinese medical science " acid regurgitation ", " acid regurgitation ", " regurgitation ", " noisy ", " dysphagic ", " stomach painful abdominal mass ", " thoracic obstruction ".Along with the development of economic society, modern's rhythm of life are accelerated, life stress strengthens, also rich and variedization gradually of dietary structure, the sickness rate of RE is also ascendant trend year by year.RE shows as multiple oesophageal irritation symptom and the outer syndrome of esophagus more, even causes bronchial asthma, obstructive sleep apnea syndrome etc., has a strong impact on patient's quality of life.Doctor trained in Western medicine is mainly by gastric acid secretion inhibiting, improves gastric motility etc. and treat, and majority can only improve clinical symptoms, easily recurrence after drug withdrawal, and Long-term taking medicine has again certain side effect.Draw through inventor's long-term practice, Chinese medicine is controlled liver-stomach disharmony type reflux esophagitis and is had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine of the treatment liver-stomach disharmony type reflux esophagitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt fragile fern, Cortex Pruni Salicinae Radicis, Rhizoma Corydalis, Pericarpium Citri junoris, Herba Pteridis Multifidae, thorn Caulis Bambusae In Taenia, anise, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Muscovitum according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine of the present invention is made up of following raw material medicaments: fragile fern 35-45 part, Cortex Pruni Salicinae Radicis 25-35 part, Rhizoma Corydalis 20-30 part, Pericarpium Citri junoris 20-30 part, Herba Pteridis Multifidae 15-25 part, thorn Caulis Bambusae In Taenia 15-25 part, anistree 10-20 part, Cortex Magnoliae Officinalis 10-20 part, Rhizoma Pinelliae 8-15 part, Muscovitum 8-15 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: 40 parts of fragile ferns, 30 parts of Cortex Pruni Salicinae Radiciss, 25 parts of Rhizoma Corydalis, 25 parts of Pericarpium Citri junoriss, 20 parts of Herba Pteridis Multifidaes, 18 parts of Caulis Bambusae In Taenia of thorn, 18 parts of anises, 15 parts of Cortex Magnoliae Officinalis, 9 parts of the Rhizoma Pinelliaes, 9 parts, Muscovitum.
The pharmacological action of Chinese medicine of the present invention is as follows:
Fragile fern: stomach function regulating, removing toxic substances.For gastropathy, the diseases such as alimentary toxicosis.
Cortex Pruni Salicinae Radicis: bitter, salty, cold, return liver, spleen, heart channel.Sending down the abnormal ascending QI, dampness, heat-clearing and toxic substances removing.Clinical in QI rising in reverse order renal mass, hygropyretic dysentery, leucorrhea with red and white discharge, quenches one's thirst, beriberi, erysipelas carbuncle sore.
Rhizoma Corydalis: acrid, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.For all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.
Pericarpium Citri junoris: acrid, bitter, warm.Return spleen, lung meridian.Circulation of qi promoting spleen invigorating, lowering the adverse-rising QI and eliminating phlegm.The clinical distension and fullness in the abdomen for stagnation of QI in spleen and stomach, nausea and vomiting, inappetence, expectorant is stopped up the cough with copious phlegm of QI rising in reverse order, and septum pectorale is full vexed, the diseases such as globus hystericus.
Herba Pteridis Multifidae: pungent, flat.Disperse exopathogen, regulating qi-flowing for harmonizing stomach.For flu, pharyngitis, conjunctival congestion and swelling pain, stomatitis, toothache, hepatitis, the diseases such as dyspepsia.
Thorn Caulis Bambusae In Taenia: micro-hardship, cool.Heat clearing away, stomach function regulating, sending down the abnormal ascending QI.Gastropyretic vomiting, singultus.
Anistree: pungent, sweet, warm.Return liver,kidney,spleen, stomach warp.Cold expelling, regulate the flow of vital energy, pain relieving.For colic of cold type stomachache, chills and pain of the waist and kness, fear of cold vomiting, the disturbance of lower legs due to pathogenic cold and dampness etc.
Cortex Magnoliae Officinalis: bitter, pungent, warm.Return spleen, stomach, large intestine channel.Circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma.For stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass vomiting and diarrhoea etc.
The Rhizoma Pinelliae: pungent, warm.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly cough with asthma abundant expectoration, feeling of oppression and fullness in the chest and epigastrium, has a headache dizzy etc.
Muscovitum: sweet, warm.GUIXIN, liver, lung, spleen, urinary bladder channel.Calm the nerves relieving convulsion, arresting bleeding and healing up ulcer.For cardiopalmus, insomnia, dizzy, epilepsy, chronic diarrhea, traumatic hemorrhage, the diseases such as eczema.
Liver-stomach disharmony type reflux esophagitis belongs to the disease categories such as the acid regurgitation, the thoracic obstruction of Chinese medicine, noisy, stomachache, regurgitation, feeling of fullness, globus hystericus.How because of due to eating and drinking without temperance, disorder of emotion impairing the spleen and stomach.In the present invention, fragile fern stomach function regulating detoxifies, is monarch drug, Cortex Pruni Salicinae Radicis sending down the abnormal ascending QI, dampness, heat-clearing and toxic substances removing, Rhizoma Corydalis dissipating blood stasis, regulating the flow of vital energy, is ministerial drug, Pericarpium Citri junoris circulation of qi promoting, sending down the abnormal ascending QI, reduces phlegm, Herba Pteridis Multifidae, thorn Caulis Bambusae In Taenia regulating qi-flowing for harmonizing stomach, anise is regulated the flow of vital energy, pain relieving, Cortex Magnoliae Officinalis circulation of qi promoting removing food stagnancy, Rhizoma Pinelliae stopping nausea and vomiting by lowering the adverse flow of QI, eliminating stagnation, Muscovitum is calmed the nerves relieving convulsion.All medicines share, long memorial liver and qi altogether, and the merit of regulating the stomach and sending down the abnormal ascending QI, reaches the effect for the treatment of liver-stomach disharmony type reflux esophagitis.
Chinese medicine of the present invention was in 2008 to 2012 clinical observation liver-stomach disharmony type reflux esophagitis 57 routine patients, and clinical report is as follows:
1, physical data
In 57 routine patients, age 26-69 year, the course of disease is many at 3 months to 4 years, 33 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
(1) there is reflux symptom;
(2) under scope, may there is the performance of reflux esophagitis;
(3) patient has causalgia after typical breastbone, heartburn, acid regurgitation symptom.
Get rid of stomach and esophagus history of operation, esophagostenosis, upper digestive tract malignant change, constitutional dyskinesis, serious accompanying diseases, anemia of pregnant woman and breast-feeding female.
Tcm clinical practice symptom: after heartburn, breastbone or pit of the stomach pain, acid regurgitation, belch, pain in the hypochondrium, feeling of oppression and fullness in the chest and epigastrium, in the time that feelings will is not smooth, symptom increases the weight of, thin lingual fur, stringy pulse or thin string.
3, Therapeutic Method
3.1 prescriptions: fragile fern 40g, Cortex Pruni Salicinae Radicis 30g, Rhizoma Corydalis 25g, Pericarpium Citri junoris 25g, Herba Pteridis Multifidae 20g, thorn Caulis Bambusae In Taenia 18g, anistree 18g, Cortex Magnoliae Officinalis 15g, Rhizoma Pinelliae 9g, Muscovitum 9g.
3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 25 days were 1 course for the treatment of at 1 dose of every day.
4, therapeutic outcome:
4.1 formulate with reference to " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
Cure: symptom disappears completely, gastroscope check Esophageal Mucosa is rotten to the corn to disappear or substantially disappears;
Effective: symptom is clearly better or substantially disappears, the rotten to the corn 1/2 above person that disappears of gastroscope check Esophageal Mucosa;
Invalid: symptom is improved not obvious, the rotten to the corn 1/2 following person that disappears of Esophageal Mucosa under gastroscope.
4.2 results: in 57 routine patients, clinical cure 38 examples, effective 13 examples, invalid 6 examples, total effective rate is 89.5%.
5, model case
5.1 tall certain, man, 51 years old.Main suit's distending pain in the chest and hypochondrium, acid regurgitation belch more than 2 months.Esophagus does in hospital and gastroscopy is shown as chronic superficial gastritis companion erosion, and gastric antrum is main, reflux esophagitis.This checks discovery, and esophagus scope is shown in that in esophagus, hypomere mucosa is shown in there is point-like hyperemia, and distal esophagus mucosa is also shown in there is the red erosion of speckle shape.Have scorching hot vexed pain after breastbone concurrently, mood is gloomy, and emotion changes is aggravation, yellow urine, and xerostomia, defecates not smooth, red tongue, yellow fur, stringy pulse.Be diagnosed as liver-stomach disharmony type reflux esophagitis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and recovery from illness, follows up a case by regular visits to and within 6 months, have no recurrence.
5.2 Liu, man, 56 years old, main stating suffered from gastropathy for many years, recently owing to feeling bad, swollen, scorching hot, the retrosternal pain in sensation gastral cavilty top, and with pantothenic acid, heartburn, xerostomia, bitter taste, drink water more, receive can, constipation with dry stool, sleeps not peaceful night.Red tongue, Artemusia lactiflora Wall. is thin, thready and stringy pulse.Gastroscopy on the same day: chronic atrophic gastritis companion gastric antrum erosion, liver-stomach disharmony type reflux esophagitis II level.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, and recovery from illness, follows up a case by regular visits to and within 6 months, have no recurrence.
5.3 Zhangs, female, 29 years old, master stated heartburn acid regurgitation more than 1 year, and before 1 year, without obviously inducement appearance is heartburn, acid regurgitation, feels sick, belch frequency, bitter taste, gastral cavity abdomen fear of cold.Receive can, the peace of sleeping, large loose stool is thin, time accompany mucus.Light red tongue, fat, crackle, white and thin fur, deep-rolling pulse is carefully slow.Gastroscopy: the hyperemia of distal esophagus mucosa, erosion and ooze out chronic gastritis.Be diagnosed as liver-stomach disharmony type reflux esophagitis.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, distending pain acid regurgitation is clearly better, and continues to take 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to and within 6 months, have no recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine for the treatment of liver-stomach disharmony type reflux esophagitis, is to be made up of fragile fern 35g, Cortex Pruni Salicinae Radicis 25g, Rhizoma Corydalis 20g, Pericarpium Citri junoris 20g, Herba Pteridis Multifidae 15g, thorn Caulis Bambusae In Taenia 15g, anistree 10g, Cortex Magnoliae Officinalis 10g, Rhizoma Pinelliae 8g, Muscovitum 8g.
Embodiment 2, a kind of Chinese medicine for the treatment of liver-stomach disharmony type reflux esophagitis, is to be made up of fragile fern 40g, Cortex Pruni Salicinae Radicis 30g, Rhizoma Corydalis 25g, Pericarpium Citri junoris 25g, Herba Pteridis Multifidae 20g, thorn Caulis Bambusae In Taenia 18g, anistree 18g, Cortex Magnoliae Officinalis 15g, Rhizoma Pinelliae 9g, Muscovitum 9g.
Embodiment 3, a kind of Chinese medicine for the treatment of liver-stomach disharmony type reflux esophagitis, is to be made up of fragile fern 45g, Cortex Pruni Salicinae Radicis 35g, Rhizoma Corydalis 30g, Pericarpium Citri junoris 30g, Herba Pteridis Multifidae 25g, thorn Caulis Bambusae In Taenia 25g, anistree 20g, Cortex Magnoliae Officinalis 20g, Rhizoma Pinelliae 15g, Muscovitum 15g.

Claims (2)

1. treat a Chinese medicine for liver-stomach disharmony type reflux esophagitis, it is characterized in that it is to be made up of following raw material medicaments:
Fragile fern 35-45 part, Cortex Pruni Salicinae Radicis 25-35 part, Rhizoma Corydalis 20-30 part, Pericarpium Citri junoris 20-30 part, Herba Pteridis Multifidae 15-25 part, thorn Caulis Bambusae In Taenia 15-25 part, anistree 10-20 part, Cortex Magnoliae Officinalis 10-20 part, Rhizoma Pinelliae 8-15 part, Muscovitum 8-15 part.
2. Chinese medicine according to claim 1, is characterized in that it is to be made up of following raw material medicaments:
40 parts of fragile ferns, 30 parts of Cortex Pruni Salicinae Radiciss, 25 parts of Rhizoma Corydalis, 25 parts of Pericarpium Citri junoriss, 20 parts of Herba Pteridis Multifidaes, 18 parts of Caulis Bambusae In Taenia of thorn, 18 parts of anises, 15 parts of Cortex Magnoliae Officinalis, 9 parts of the Rhizoma Pinelliaes, 9 parts, Muscovitum.
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CN103705591B (en) * 2013-12-27 2015-06-24 唐晓春 Traditional Chinese medicine preparation for treating reflux esophagitis
CN104116808B (en) * 2014-07-14 2017-01-25 张英剑 A traditional Chinese medicine mixture assisting treatment of gastroesophageal reflux disease, a preparing method thereof and applications of the mixture
CN104288563A (en) * 2014-10-08 2015-01-21 邱香廷 Traditional Chinese medicine preparation for treating reflux esophagitis of old people
CN105106359A (en) * 2015-10-08 2015-12-02 郑伟 Traditional Chinese medicine for treating liver-depression-into-heat reflux esophagitis

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CN101757601B (en) * 2010-04-07 2011-03-23 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composite for treating esophageal rheumatism and preparation method thereof
CN102580019A (en) * 2011-01-14 2012-07-18 天津市中宝制药有限公司 Chinese medicinal composition for treating reflux esophagitis
CN103083631B (en) * 2012-12-11 2014-04-16 宋协勘 Traditional Chinese medicine for treating reflux esophagitis
CN103120770B (en) * 2013-02-15 2014-03-26 毕月阳 Preparation method of traditional Chinese medicine for treating constipation-predominant reflux esophagitis

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