CN104974134A - 甲磺酸伊马替尼的精制方法 - Google Patents
甲磺酸伊马替尼的精制方法 Download PDFInfo
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- CN104974134A CN104974134A CN201510254423.0A CN201510254423A CN104974134A CN 104974134 A CN104974134 A CN 104974134A CN 201510254423 A CN201510254423 A CN 201510254423A CN 104974134 A CN104974134 A CN 104974134A
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- CN
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- Prior art keywords
- imatinib
- imatinib mesylate
- organic solvent
- solvent
- pyridin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510254423.0A CN104974134B (zh) | 2015-05-19 | 2015-05-19 | 甲磺酸伊马替尼的精制方法 |
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CN201510254423.0A CN104974134B (zh) | 2015-05-19 | 2015-05-19 | 甲磺酸伊马替尼的精制方法 |
Publications (2)
Publication Number | Publication Date |
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CN104974134A true CN104974134A (zh) | 2015-10-14 |
CN104974134B CN104974134B (zh) | 2017-01-18 |
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CN201510254423.0A Active CN104974134B (zh) | 2015-05-19 | 2015-05-19 | 甲磺酸伊马替尼的精制方法 |
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CN (1) | CN104974134B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114685428A (zh) * | 2020-12-29 | 2022-07-01 | 重庆圣华曦药业股份有限公司 | 甲磺酸伊马替尼的制备方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009060463A1 (en) * | 2007-11-05 | 2009-05-14 | Natco Pharma Limited | An environmentally friendly process for the preparation of imatinib base |
WO2011095835A1 (en) * | 2010-02-02 | 2011-08-11 | Actavis Group Ptc Ehf | Highly pure imatinib or a pharmaceutically acceptable salt thereof |
WO2011157450A1 (en) * | 2010-06-18 | 2011-12-22 | Krka, D. D., Novo Mesto | New polymorphic form of imatinib base and preparation of salts thereof |
WO2012004801A1 (en) * | 2010-07-07 | 2012-01-12 | Hetero Research Foundation | Process for imatinib mesylate |
WO2012131711A1 (en) * | 2011-03-31 | 2012-10-04 | Ind-Swift Laboratories Limited | Improved process for preparation of imatinib and its mesylate salt |
US20130203990A1 (en) * | 2010-07-29 | 2013-08-08 | Dr. Reddy's Laboratories, Inc. | Process for the preparation of imatinib mesylate |
CN104072477A (zh) * | 2013-07-26 | 2014-10-01 | 江苏豪森药业股份有限公司 | 伊马替尼的精制方法 |
-
2015
- 2015-05-19 CN CN201510254423.0A patent/CN104974134B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009060463A1 (en) * | 2007-11-05 | 2009-05-14 | Natco Pharma Limited | An environmentally friendly process for the preparation of imatinib base |
WO2011095835A1 (en) * | 2010-02-02 | 2011-08-11 | Actavis Group Ptc Ehf | Highly pure imatinib or a pharmaceutically acceptable salt thereof |
WO2011157450A1 (en) * | 2010-06-18 | 2011-12-22 | Krka, D. D., Novo Mesto | New polymorphic form of imatinib base and preparation of salts thereof |
WO2012004801A1 (en) * | 2010-07-07 | 2012-01-12 | Hetero Research Foundation | Process for imatinib mesylate |
US20130203990A1 (en) * | 2010-07-29 | 2013-08-08 | Dr. Reddy's Laboratories, Inc. | Process for the preparation of imatinib mesylate |
WO2012131711A1 (en) * | 2011-03-31 | 2012-10-04 | Ind-Swift Laboratories Limited | Improved process for preparation of imatinib and its mesylate salt |
CN104072477A (zh) * | 2013-07-26 | 2014-10-01 | 江苏豪森药业股份有限公司 | 伊马替尼的精制方法 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114685428A (zh) * | 2020-12-29 | 2022-07-01 | 重庆圣华曦药业股份有限公司 | 甲磺酸伊马替尼的制备方法 |
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Publication number | Publication date |
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CN104974134B (zh) | 2017-01-18 |
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C41 | Transfer of patent application or patent right or utility model | ||
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Address after: 222006 Jiangsu province Lianyungang Kaitai Dapu Industrial Zone, economic and Technological Development Zone Road Applicant after: Lianyungang Hongchuang Pharmaceutical Co.,Ltd. Applicant after: JIANGSU HANSOH PHARMACEUTICAL GROUP Co.,Ltd. Address before: 222006 Jiangsu province Lianyungang Kaitai Dapu Industrial Zone, economic and Technological Development Zone Road Applicant before: Lianyungang Hongchuang Pharmaceutical Co.,Ltd. Applicant before: Jiangsu best Pharmaceutical Co.,Ltd. Address after: 222006 Jiangsu province Lianyungang Kaitai Dapu Industrial Zone, economic and Technological Development Zone Road Applicant after: Lianyungang Hongchuang Pharmaceutical Co.,Ltd. Applicant after: Jiangsu best Pharmaceutical Co.,Ltd. Address before: 222006 Jiangsu province Lianyungang Kaitai Dapu Industrial Zone, economic and Technological Development Zone Road Applicant before: Lianyungang Hongchuang Pharmaceutical Co.,Ltd. Applicant before: JIANGSU HANSOH PHARMACEUTICAL Co.,Ltd. |
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Effective date of registration: 20160426 Address after: 222047 Lianyungang economic and Technological Development Zone, Jiangsu Applicant after: JIANGSU HANSOH PHARMACEUTICAL GROUP Co.,Ltd. Address before: 222006 Jiangsu province Lianyungang Kaitai Dapu Industrial Zone, economic and Technological Development Zone Road Applicant before: Lianyungang Hongchuang Pharmaceutical Co.,Ltd. Applicant before: JIANGSU HANSOH PHARMACEUTICAL GROUP Co.,Ltd. |
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