CN104970037A - Insecticide compositioncontainingpymetrozine and dinotefuran - Google Patents
Insecticide compositioncontainingpymetrozine and dinotefuran Download PDFInfo
- Publication number
- CN104970037A CN104970037A CN201510466480.5A CN201510466480A CN104970037A CN 104970037 A CN104970037 A CN 104970037A CN 201510466480 A CN201510466480 A CN 201510466480A CN 104970037 A CN104970037 A CN 104970037A
- Authority
- CN
- China
- Prior art keywords
- pymetrozine
- mti
- agent
- combination
- pesticidal combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses an insecticide composition containingpymetrozine and dinotefuran. The insecticide composition comprises pymetrozine and dinotefuran, serving as active ingredients,wherein the weight ratio of pymetrozine to dinotefuran is7.41:1 to 600:1. According to the formula, through reasonable mixing of pymetrozine and dinotefuran, the pesticide effect is improved, pesticide resistance of brown rice planthopper to pymetrozine and dinotefuran is delayed, the use mount of pesticides is lowered, environment pollution is alleviated effectively, the cost is low, the economic burden of farmers is alleviated, and the requirement on sustainable development is met. The insecticide composition also has the characteristics of high efficiency and safety.
Description
Technical field
The invention belongs to a kind of insecticidal technology field containing pyridine compounds and their and anabasine compound, more specifically relate to a kind of Pesticidal combination containing pymetrozine and MTI-446, also relate to a kind of preparation method containing pymetrozine and dinotefuran mixed preparation simultaneously, it is applicable to control thorn and inhales the pest such as class pest brown planthopper, white-backed planthopper, small brown rice planthopper, long green plant hopper, aphid, Bemisia tabaci, Trialeurodes vaporariorum Westwood, leafhopper, paddy rice thrips, can also hold concurrently anti-snout moth's larva, rice leaf roller, rice leaf beetles, oryza chinensis, a red-spotted lizard class, striped flea-beetle, stinkbug etc. simultaneously.
Background technology
Rice fulgorid is the primary pest on paddy rice, it is mainly through thorn water suction rice nutrient solution and the sick damage to crops of transmitted virus, the long-term hazard area of rice fulgorid is at about 400,000,000 mu, endanger the light time and cause grain drop in production, the time that harm weighs causes grain to have no harvest, serious economic loss is brought, so in order to can produce sufficient food and reduce economic loss, must prevent and treat brown planthopper to peasant.Due to the instant effect of chemical control and Be very effective, therefore a large amount of chemical pesticides is spilt to farmland, causes environmental pollution, have impact on grain security, and simultaneously because a large amount of continuous print of agricultural chemicals uses, rice fulgorid creates pesticide resistance to dissimilar chemical pesticide.It is rampant again that the application of organic phosphor, chrysanthemum ester insecticide simultaneously causes rice fulgorid simultaneously, and it is more and more serious that the drug-fast generation of rice fulgorid makes rice fulgorid occur.
The chemical agent of current control brown planthopper mainly contains organic phosphates, carbamates, pyrethroid, anabasine, phenyl pyrazoles, pyridines, insect growth regulator, IGR class, anabasine insecticide.But the medicament in the market for preventing and treating brown planthopper is mainly pymetrozine and anabasine insecticide.Because long-term, continuous print use single chemical control rice fulgorid, cause agricultural chemicals to rice fulgorid continuous print Selective Pressure, insect rice fulgorid is easily made to develop immunity to drugs, mechanism of action is different, without mutual drug-fast medicament mixture, the Selective Pressure that single continuous use chemical control brown planthopper produces can be reduced, slow down rice fulgorid development of drug resistance, reduce pesticide dosage, reduce environmental pollution, increase grain security, meet the policy that country reduces fertilizer and pesticide usage amount.
In order to effectively prevent and treat brown planthopper, extend the time that brown planthopper produces pymetrozine and anabasine insecticide pesticide resistance, our science filtered out the compounded combination of pymetrozine and MTI-446.This combination has good control efficiency to rice fulgorid, can time of producing of delaying drug resistance, reduces the consumption of agricultural chemicals, reduces the harm to natural enemy biology, reduce environmental pollution, alleviate the financial burden of peasant, reduce persticide residue, increase grain security.
Pymetrozine is the new pyridine insecticides of Jia Ji company of Switzerland exploitation, has unique mode of action, has fine preventive effect to sucking pest.Pymetrozine does not knock down activity to insect, and can not produce direct toxicity to insect, contacting pests will produce lancet blocking effect to pymetrozine, stops immediately taking food, hungry and dead, does not report that pymetrozine and other medicaments have cross resistance at present.The preventive effect of pymetrozine to insects such as brown planthopper, aphid, aleyrodids has good lasting effect, can with quick-acting pharmacy mix, field drug-fastness Population of Rice Brown Planthopper can be prevented and treated.
MTI-446 is the third generation nicotinic insecticide of Mitsui chemical company scientific research personnel exploitation.The chemical constitution of itself and existing nicotinic insecticide (Imidacloprid, Acetamiprid, Nitenpyram, Diacloden, clothianidin, thiacloprid) is far from each other, but the same with all anabasine compounds, has insecticidal activity that is efficient, wide spectrum.This medicament insecticidal spectrum is wide, has remarkable interior suction osmosis, and namely shows very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, to crop without poisoning, can be used for numerous crops such as paddy rice, fruit tree, vegetables.MTI-446, listing in 2002, is mainly used in preventing and treating sucking pest, has certain preventive effect simultaneously to lepidoptera pest.
Summary of the invention
The object of the invention is to there are provided a kind of Pesticidal combination containing pymetrozine and MTI-446, this formula, by the rational mixture between pymetrozine and MTI-446, improves drug effect; Delay the brown time flying that pymetrozine and MTI-446 are developed immunity to drugs; Reduce the usage amount of agricultural chemicals, effectively alleviate the pollution to environment, reduce the harm to beneficial organism; With low cost, also reduce the financial burden of peasant simultaneously, meet the requirement of sustainable development; Resistance management can be carried out to rice fulgorid, to Imidacloprid, Diacloden, Buprofezin, pymetrozine produce high level drug-fast brown planthopper field population higher preventive effect; Reduce the toxic action to natural enemy, be conducive to alleviating the pollution to environment, improve quality, the safety of food; Extend controlling object; A kind of water baseization, safe, environmentally friendly, efficient formulation are provided.
Another object of the present invention is the preparation method that there are provided a kind of pymetrozine and dinotefuran mixed preparation, pymetrozine is different from the mechanism of action of MTI-446, lasting effect and quick-acting are also different, them are made used in combinationly in field to have given full play to complementary advantage, can efficiently kill pests brown planthopper, white-backed planthopper, small brown rice planthopper, long green plant hopper, aphid, aleyrodid, thrips, leafhopper, diaphorina citri, improve preventive effect, the insects such as anti-striped rice borer, rice leaf roller of simultaneously can also holding concurrently;
Present invention also offers a kind of pymetrozine and MTI-446 bucket mixes technology, the formulation that pymetrozine and MTI-446 use in the present invention is water dispersible granules or suspending agent or wetting powder, and this formulation is environmentally friendly, simultaneously to operator safety simultaneously; Due to be two kinds of single doses in field direct mixture, the complicated processes avoiding enterprise to register mixture preparation, has saved time and the cost of enterprise.
In order to realize above-mentioned object, the present invention adopts following technical measures:
Contain a Pesticidal combination for pymetrozine and MTI-446, comprise active ingredient pymetrozine and active component MTI-446, pymetrozine and MTI-446 weight ratio are (7.41:1) ~ (600:1).
Contain a Pesticidal combination for pymetrozine and MTI-446, pymetrozine and MTI-446 weight ratio are (7.41:1) ~ (66.7:1).
Contain a Pesticidal combination for pymetrozine and MTI-446, pymetrozine and MTI-446 weight ratio are (16.67:1) ~ (266.67:1).
Contain a Pesticidal combination for pymetrozine and MTI-446, pymetrozine and MTI-446 weight ratio are (28.57:1) ~ (155.56:1).
Contain a Pesticidal combination for pymetrozine and MTI-446, pymetrozine and MTI-446 weight ratio are (44.44:1) ~ (155.56:1).
The described Pesticidal combination system containing pymetrozine and MTI-446, this formula is mixed by a certain percentage by pymetrozine and MTI-446, after mixing, the weight of MTI-446 active component accounts for the ratio of Active principals weight is 0.17-11.89%, accounts for the 0.08-5.95% of total prescription quality; The ratio that pymetrozine active component weight accounts for Active principals weight is 88.11-99.83%, accounts for the 44.05-49.92% of total prescription quality, the weight sum that the weight of described Active principals is MTI-446 and pymetrozine.
Gu described a kind of Pesticidal combination containing pymetrozine and MTI-446 makes missible oil, wetting powder, suspending agent, water dispersible granules, solid/bucket mixture, ultra low volume spraying agent, effervescent tablet.
The bactericidal composition of invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing, then adds surfactant as one or more in dispersant, wetting agent, binding agent, defoamer etc. by active component with liquid flux or solid carrier.According to different dosage form, in preparation, stabilizing agent known in those skilled in the art, antifreeze etc. can also be contained.
Described a kind of Pesticidal combination containing pymetrozine and MTI-446, it is characterized in that: composition makes suspending agent, suspending agent thing preparation method step is:
A, take raw material by component design:
Former for pymetrozine medicine and the former medicine of MTI-446 are put into container, then adds wetting agent, dispersant, antifreezing agent, thickener, stir;
B, at a high speed (1000 turn left the right side) stir pre-dispersed 25-35min (emulsifying), then stop stirring, and add sanding media, start sand milling;
C, (frosted is about 1.8-2.2h) stop sand milling to more than 98% suspended particulate particle diameter between 0.1-0.7 μm, filter, go out bead, add other auxiliary agent (defoamer, stabilizing agent, preservative, solvent), obtain homogeneous phase formulation;
Described wetting agent is neopelex, Morwet EFW (composition is the mixture of alkyl naphthalene sulfonic acid sodium salt and anion wetting agent, Aksu Bel), Terspense4896 (alkyl phenol polyether class wetting dispersing agent), nekal, dioctyl sodium sulfosuccinate, tea are withered, GY-W04 (polycarboxylate wetting agent), dense breast-500, dense newborn 700, NP-10 (polyoxyethylene nonylphenol ether), one or more any combination in 2201 (multiple non-ionic surface active agents and anion surfactant is composite form) etc.;
Described dispersant is GY-D06 (polycarboxylate salt dispersant), Morwet D-425 (sodium salt of alkylnaphthalene sulfonate formaldehyde condensation products), Morwet D-110 (alkylnaphthalene sulfonate formaldehyde condensation products+APE carboxylate), terspense 2425 (alkylnaphthalene sulfonate formaldehyde condensation products anionoid efficient general type dispersant), terspense2700 (tailored version dispersant, UT product Co., Ltd), sodium lignin sulfonate, naphthalenesulfonate condensation compound, alkylnaphthalene sulfonate, sulphonyl succinate, alkylaryl sulfonates, lignosulfonates, CMC (CMC), PVA (polyvinyl alcohol), PVP (polyvinylpyrrolidone), one or more any combination in XG (xanthans) etc.,
Described antifreezing agent is any combination of a kind of in ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), the third ethanol, glycerine-ether diglycol or two to six kinds;
Described defoamer is organosilicon ketone, polyether silicone, C
8-10fatty alcohol, C
10-20in aliphatic saturated monocarboxylic acid and lipid thereof, polyglycerol, ester-ether type compound etc. in one or more any combination;
Described thickener is one or more any combination in polyethylene glycol, xanthan gum, carboxymethyl cellulose, Sodium Polyacrylate, gaseous silicon oxide, bentonite, Magnesiumaluminumsilicate etc.;
Described stabilizing agent is one or more any combination in bentonite, white carbon, lightweight sodium silicate etc.;
Described preservative is one or more any combination in formaldehyde, paraformaldehyde, Sodium Benzoate, benzoic acid etc.
Described solvent is one or more any combination in water, dimethyl formamide, dimethyl sulfoxide (DMSO), dimethylbenzene, mineral oil, plant wet goods.
Contain a Pesticidal combination for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Composition comprises following component and content when making water dispersible granules: active ingredient pymetrozine 44.05% ~ 49.92%, active component MTI-446 0.08% ~ 5.95%, dispersant 2% ~ 5%, wetting agent 2% ~ 5%, disintegrant 0% ~ 15%, binding agent 0% ~ 15%, filler surplus.
Composition comprises following component and content when making effervescent tablet: active ingredient pymetrozine 26.43% ~ 29.95%, active component MTI-446 0.05% ~ 3.57%, dispersant 2% ~ 5%, wetting agent 2% ~ 5%, disintegrant 0% ~ 15%, binding agent 0% ~ 15%, filler surplus.
Composition comprises following component and content when making barrel mixture: active ingredient pymetrozine 88.11% ~ 99.83%, active component MTI-446 0.17% ~ 11.89%, pymetrozine can be 60% water dispersible granules, 50% wetting powder, 25% suspending agent, 50% effervescent tablet, and MTI-446 can be 20% soluble concentrate, 25% wetting powder, 20% water dispersible granules, 20% suspending agent.
Composition comprises following component and content when making ultra low volume spraying agent: active ingredient pymetrozine 44.05% ~ 49.92%, active component MTI-446 0.08% ~ 5.95%, emulsifier 5 ~ 10%, surplus are solvent.
Composition comprises following component and content when making missible oil: active ingredient pymetrozine 17.62% ~ 19.97%, active component MTI-446 0.03% ~ 2.38%, emulsifier 5 ~ 10%, surplus are solvent.
Composition comprises following component and content when making wetting powder: active ingredient pymetrozine 44.05% ~ 49.92%, active component MTI-446 0.08% ~ 5.95%, dispersant 3% ~ 6%, wetting agent 1% ~ 3%, carrier surplus.
Described disintegrant is one or more in urea, ammonium sulfate, sodium cellulose glycolate (CMC-Na), citric acid, sodium bicarbonate, sodium carbonate;
Described filler is one or more in potter's clay, diatomite, kaolin, white carbon, concave convex rod, precipitated calcium carbonate;
Described binding agent is one or more in sucrose, starch, PVP, soluble starch.
Described emulsifier is one or more in agriculture breast 500, Nongru-700,1602# (triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer), NP-10 (polyoxyethylene nonylphenol ether), 0201B (special nonionic and anion surfactant), 2201 (composite emulsifier, the compounds of anion and non-ionic surface active chaste tree and molten chaste tree), 0203B (special nonionic and anion surfactant); .
In pymetrozine provided by the invention and dinotefuran mixed combination, the mass ratio of pymetrozine and MTI-446 is: 7.41:1,16.67:1,28.57:1,44.44:1,66.67:1,100:1,155.56:1,266.67:1,600:1, pymetrozine and the preferred mass ratio of dinotefuran mixed formula are: 7.41:1,28.57:1,66.67:1,155.56:1,600:1.
The present invention compared with prior art, has the following advantages and effect:
1. pymetrozine and MTI-446 composite after, improve drug effect, the time that delaying drug resistance produces, extend pymetrozine, MTI-446 service life.
2. pymetrozine mixed with MTI-446 after, the consumption of mixture reduces, and reduces production cost, decreases peasant burden.
3. two kinds of medicaments owing to selecting are all the insecticides of high-efficiency low-toxicity, can reduce the toxic action to natural enemy, be conducive to alleviating the pollution to environment, improve quality, the safety of food.
4. the agricultural chemicals single dose that two kinds can have been registered by this formula directly carries out mixture (namely have developed a barrel mix formulation) in field, avoid the re-registration process of Mixed Pharmacy, provide convenience for enterprise produces, saved enterprise's production cost, reduce peasant's drug cost.
5. administer the field population, particularly high-level drug-fast pest population that develop immunity to drugs to Imidacloprid, Buprofezin, Diacloden, after medicine, 15 days preventive effects are more than 96%, and after medicine, the preventive effect of 21 days reaches more than 90%.
6. extend controlling object, due to MTI-446 can water prevention rice borer, rice leaf roller, therefore, pymetrozine and dinotefuran mixed combination not only can prevent and treat the Hemipteran pest such as Bemisia tabaci, aphid, brown planthopper, white-backed planthopper, small brown rice planthopper, long green plant hopper, diaphorina citri, thrips, leafhopper and can to hold concurrently the lepidoptera pests such as the anti-snout moth's larva of rice, rice leaf roller.
7. the formulation Environmental Safety of the application, water baseization, safety, efficiently reduces pollution to environment.
Embodiment
Embodiment 1:
Contain a suspending agent for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Contain a Pesticidal combination formulation preparation method for pymetrozine and MTI-446, the steps include:
A, by component design, take pymetrozine and the former medicine of MTI-446, put into container, then add lauryl sodium sulfate, nekal, lignin sulfonic acid sodium salt and naphthalene sulphonate formaldehyde polymer, glycerine, AF9903, lightweight sodium silicate, polyethylene glycol, water etc., stir;
B, at a high speed (1000 turns) stir, pre-dispersed 25-35min, then stop stirring (stirring completely), add sanding media, start sand milling;
Stop sand milling (to more than 98% suspended particulate particle diameter between 0.1-0.7 μm) after C, 1.8-2.2h, filter, go out bead, add other auxiliary agent (Sodium Benzoate), stir, obtain homogeneous phase formulation.
Embodiment 2:
Contain a suspending agent for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Contain a Pesticidal combination formulation preparation method for pymetrozine and MTI-446, with embodiment 1.
The auxiliary agents such as described lauryl sodium sulfate can use that Morwet EFW (composition is the mixture of alkyl naphthalene sulfonic acid sodium salt and anion wetting agent, Aksu Bel), Terspense4896 (alkyl phenol polyether class wetting dispersing agent), nekal, dioctyl sodium sulfosuccinate, tea are withered, a kind of or two to six kinds any combination in GY-W04 (polycarboxylate wetting agent) etc. replaces.
Embodiment 3:
Contain a suspending agent for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Contain a Pesticidal combination formulation preparation method for pymetrozine and MTI-446, with embodiment 1.
Embodiment 4:
Contain a water dispersible granules for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Containing the Pesticidal combination formulation preparation method that pymetrozine and furan worm are pressed, the steps include:
A, the sample such as pymetrozine, MTI-446, wetting agent (lauryl sodium sulfate and Morwet EFW (1:1)), dispersant (Morwet D-425 and naphthalene sulphonate formaldehyde polymer (3:4)), filler (diatomite), disintegrant (starch) to be weighed up by component design, mixing, high speed disintegrator is pulverized;
Sample after B, pulverizing is placed in beaker, adds the water (amount of water is the 10-20% of material total amount) containing binding agent while stirring, tentatively can pinch into mud, then add extruder grain in comminutor;
C, finally the particle squeezed out is placed in 30-40 DEG C of baking oven, dry, moisture is that 0.5-1.0% is advisable.
Embodiment 5:
Contain an effervescent tablet for pymetrozine and MTI-446, it is made up of the raw material of following mass fraction:
Containing the Pesticidal combination formulation preparation method that pymetrozine and furan worm are pressed, the steps include:
A, by component design, take pymetrozine and the former medicine of MTI-446, put into container, then lauryl sodium sulfate and NNO (sodium methylene bis-naphthalene sulfonate), lignin sulfonic acid sodium salt and naphthalene sulphonate formaldehyde polymer, citric acid and starch, dextrin, white carbon and diatomaceous earth sample is added, mix, obtain a kind of mixture;
B, mixture is placed on high-energy crushing machine and pulverizes 8-12min (200 order), then in airslide disintegrating mill, pulverize (200 order), make the pulvis of 40%;
C, pulvis is counted binding agent (dextrin) aqueous solution, stir, dry, compressing tablet.
Embodiment 6:
Contain a ultra low volume spraying agent agent preparation method for pymetrozine and MTI-446, it is made up of the raw material of following weight portion:
Contain a Pesticidal combination formulation preparation method for pymetrozine and MTI-446, the steps include:
A, by component design, take MTI-446 and the former medicine of pymetrozine, add dimethyl sulfoxide (DMSO), dissolve former medicine;
B and then add 1-METHYLPYRROLIDONE, stir, add dense newborn 500 and dense newborn 700, stir (100-200 rev/min), stirs the liquid preparation that 30-40min obtains transparent and homogeneous.Ultra low volume spraying agent performance indications reference table 9, storage-stable is good without precipitation.
Embodiment 7:
The Pesticidal combination bucket mix formulation preparation method and the bucket thereof that contain pymetrozine and MTI-446 mix a technology,
Material quality percentage %
Bucket mixture 1:50% pymetrozine water dispersing granule 74.77
Bucket mixture 2:20% MTI-446 water dispersible granules 25.23
Contain Pesticidal combination bucket mixture preparation method and the mixed method of pymetrozine and MTI-446, the steps include:
A, experimentally to design respectively, pymetrozine and MTI-446 are made water dispersible granules, suspending agent, soluble granule or wetting powder.
B, by calculate consumption take 50% pymetrozine water dispersing granule or wetting powder, add water 1000-2000ml, stir, dissolve;
C, after 50% pymetrozine water dispersing granule or wetting powder dissolve, add 20% MTI-446 water dispersible granules, stir;
D, the mother liquor prepared will carry out secondary dilution, secondary dilution is carried out within 14-16min, when dilution agricultural chemicals single dose is used with, the method for preparation mixture liquid is generally the liquid first preparing a kind of single dose with enough water, then dilutes another kind of single dose with this liquid; And first can not mix two kinds of single doses, then dilute with water, to avoid bad reaction, comprise the destruction of active ingredient and the deterioration of physical behavior.First time carries out two kinds of single dose tentative existing mixed existing used times, first can test a small amount of admixing medical solutions in transparent glass container, observe whether have the abnormalities such as oil slick, flocculation, precipitation or variable color, heating, generation bubble.All liquids demonstrate and create chemical change or liquid physical behavior worsens to some extent, and this mixture is just inadvisable.The performance of water dispersant and bucket mixture performance indications reference table 7 and table 8.
When table 1 is barrel mixed, pesticidal preparations uses stability with
Pymetrozine and dinotefuran mixed combination are to brown planthopper indoor virulence test
The best compatibility of A and B mixture is determined in this experiment according to being total to malicious factorization method, again according to summation action line in equivalent line ten Along ents setting A and B proportioning be 1:9,2:8,3:7,4:6,5:5,6:4,7:3,8:2,9:1, then calculate co-toxicity coefficient by toxicity test result.Malicious factor >20 altogether, representing that two single doses are mixed has synergistic effect; ≤-20 indicate antagonism, and-20 ~ 20 represent summation action.Co-toxicity coefficient >=120 are synergistic effect, and co-toxicity coefficient≤80 are antagonism, and 80 ~ 120 is summation action.
For examination insect: within 2006, picking up from experimental field, Hunan academy of agricultural sciences, raising so far when not contacting any medicament.
Sod cultivation: rice-stem dipping method, grub out and get the rice strain of healthy and strong consistent tillering regularity to the booting initial stage, clean, be cut into company's root rice stem that about 10cm is long, 3 strains 1 group, dry in the air in the cool to surface without washmarking, take out after rice stem is soaked 30s in liquid and dry, encase root with the absorbent cotton of dipping and put into disposal plastic cup, support from field label taking the paddy rice of worm net accurate consistent 3 mid-term in age nymph, the disposal plastic cup that the level of putting into is sidelong, 20 every glass, it is vertical more all to climb up after rice stem or wall of cup until nymph, reject the individuality of mechanical damage, and supply 20, each concentration repeats 3 times, take clear water as contrast.Putting into temperature after connecing worm is 27 ± 1 DEG C, and the photoperiod is cultivate in the constant temperature climatic cabinate of L:D=16:8h.Note the absorbent cotton moisturizing of rice stem root after process, anti-rice stem is withered.Review time: check result after pesticide treatments 168h.
Pymetrozine and MTI-446 different ratio make same one dosage type low temperature (suspending agent, auxiliary agent ratio adopts proportioning in embodiment 1)
Table 2 pymetrozine and MTI-446 different ratio to 3 age brown planthopper nymph the common malicious factor
| Group | Content (pymetrozine+MTI-446) mg/L | Active ingredient mass ratio | The malicious factor altogether |
| 1 | 20+2.7 | 7.41:1 | 20.4 |
| 2 | 40+2.4 | 16.67:1 | 24.54 |
| 3 | 80+1.8 | 44.44:1 | 44.63 |
| 4 | 100+1.5 | 66.67:1 | 44.48 |
| 5 | 120+1.2 | 100:1 | 34.74 |
| 6 | 160+0.6 | 266.67:1 | 23.52 |
| 7 | 180+0.3 | 600:1 | 54.49 |
| 8 | 60+2.1 | 28.57:1 | 18.91 |
| 9 | 140+0.9 | 155.56:1 | 43.99 |
Table 3 pymetrozine and MTI-446 different ratio to 3 age brown planthopper nymph co-toxicity coefficient
| Group | Active ingredient mass ratio | Co-toxicity coefficient |
| 1 | 66.67:1 | 239.29 |
| 2 | 600:1 | 172.95 |
| 3 | 7.41:1 | 501.87 |
| 4 | 28.57:1 | 390.13 |
| 5 | 155.56:1 | 345.19 |
As can be seen from table 2,3, in pymetrozine and each dinotefuran mixed ratio, the common malicious factor of group 1,2,3,4,5,6,7,9 is greater than 20 (see table 2), the co-toxicity coefficient of group 1,2,3,5,5 is all greater than 120 (see table 3), all there is obvious synergistic effect, wherein choose 7.41:1,28.57:1,66.67:1 tri-ratios do field trial.
2. field trial
The test of pesticide effectiveness is carried out at Hubei Province's Wuxue City, and paddy rice is semilate rice, kind Yue You 9113, and carry out rice fulgorid control experiment on September 2nd, 2014, adopt WBD-16 type knapsack sprayer, spray after being diluted on request by liquid, each plot area is 25m
2, every mu of water consumption is 45L, each process 4 repetition, and once, after dispenser, 3d, 7d, 14d, 21d investigate its control efficiency to spray medicine, and 5 points are investigated in each community, and often some investigation 5 pockets, record data, analytic statistics result of the test also carries out significance of difference analysis.
Table 4 pymetrozine and MTI-446 different ratio are to the control efficiency of field Population of Rice Brown Planthopper
As can be seen from Table 4, the quick-acting of pymetrozine is poor, but continuation is better, the continuation of two mixtures is also better, analyzed by the significance of difference, two mixtures to the control efficiency to rice fulgorid of the control efficiency of rice fulgorid and pymetrozine at 3 days, 7 and 14 everyday time there is not significant difference, namely reduce dosage and still can reach identical control efficiency, but to the control efficiency of rice fulgorid and pymetrozine there is significance and pole significant difference in the control efficiency to rice fulgorid to 1 mixture after 21 days, namely when reducing dosage, preventive effect is better than pymetrozine, simultaneously 3 days, 7 days, 15 days, 21 days time pymetrozine and dinotefuran mixed preparation to the preventive effect of the preventive effect of rice fulgorid higher than pymetrozine.
Hundred root and stem of certain plants worm amounts of leafhopper before and after table 5 chemicals treatment
The mixture of pymetrozine and MTI-446 is to the preventive effect of the preventive effect of leafhopper higher than pymetrozine and MTI-446 single dose.
Table 6 Wuxue City brown planthopper in 2012 is to the pesticide resistance (indoor feeding 5 generation) of Imidacloprid, Buprofezin and Diacloden
Fold resistance's classification: RR≤3, responsive; 3≤RR<5, susceptibility declines; 5≤RR<10, low-level pesticide resistance; 10≤RR<40, medium level pesticide resistance; 40≤RR<160, high-level pesticide resistance; RR >=160, high horizontal pesticide resistance.
From upper table (table 6), Wuxue City brown planthopper field population creates extremely high-caliber pesticide resistance to Imidacloprid, Buprofezin, creates high-caliber pesticide resistance to Diacloden.From table 5, table 6, pymetrozine and dinotefuran mixedly to the brown planthopper that Imidacloprid, Buprofezin, Diacloden have produced high-level resistance, still there is higher preventive effect.Pymetrozine and the synergistic effect possible cause 1. of MTI-446 to brown planthopper suppress the main detoxification enzyme activity in body; 2. reduce surface tension after two kinds of medicine mixing; 3. after two kinds of medicine mixing, improve the penetration capacity to blade and insect body wall; 4. may create new target.
Table 7 pymetrozine MTI-446 water dispersible granules performance indications
Table 8 pymetrozine MTI-446 bucket mixture performance indications
Table 9 pymetrozine MTI-446 ultra low volume spraying agent performance indications
Table 10 pymetrozine and MTI-446 different ratio resist Imidacloprid and Buprofezin 3 field in age Population of Rice Brown Planthopper nymph co-toxicity coefficient
| Group | Active ingredient mass ratio | Co-toxicity coefficient |
| 1 | 116.67:1 | 180.24 |
| 2 | 75:1 | 369.99 |
| 3 | 250:1 | 500.09 |
| 4 | 33.33:1 | 405.67 |
As shown in Table 10, pymetrozine and MTI-446, when 116.67:1,75:1,250:1,33.33:1, still have synergistic effect to antagonism Imidacloprid and Buprofezin 3 field in age Population of Rice Brown Planthopper, spend coefficient together and be all greater than 120.
Claims (7)
1. contain a Pesticidal combination for pymetrozine and MTI-446, it is characterized in that: comprise active ingredient pymetrozine and active component MTI-446, pymetrozine and MTI-446 weight ratio are 7.41:1 ~ 600:1.
2. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to claim 1, is characterized in that: pymetrozine and MTI-446 weight ratio are 7.41:1 ~ 600:1.
3. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to claim 1, is characterized in that: pymetrozine and MTI-446 weight ratio are 16.67:1 ~ 266.67:1.
4. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to claim 1, is characterized in that: pymetrozine and MTI-446 weight ratio are 28.57:1 ~ 155.56:1.
5. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to claim 1, is characterized in that: pymetrozine and MTI-446 weight ratio are 44.44 ~ 155.56.
6. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to any one of claim 1-5, is characterized in that: Gu composition makes missible oil, wetting powder, suspending agent, water dispersible granules, solid/bucket mixture, ultra low volume spraying agent and effervescent tablet.
7. a kind of Pesticidal combination containing pymetrozine and MTI-446 according to any one of claim 1-5, it is characterized in that: composition makes suspending agent, suspending agent thing preparation method step is:
A, take raw material by component design:
Material quality mark %
The former medicine 50 of the former medicine+MTI-446 of pymetrozine
Wetting agent 0.2-5
Dispersant 0.3-5
Antifreezing agent 1-10
Defoamer 0.1-5
Thickener 0.2-5
Stabilizing agent 0.1-10
Preservative 0.1-0.5
Solvent 10-49,
Former for pymetrozine medicine and the former medicine of MTI-446 are put into container, then adds wetting agent, dispersant, antifreezing agent, thickener, stir;
The pre-dispersed 25-35min of B, high-speed stirred, then stops stirring, adds sanding media, start sand milling;
C, between 0.1-0.7 μm, stop sand milling to more than 98% suspended particulate particle diameter, filter, go out bead, add defoamer, stabilizing agent, preservative and solvent, obtain homogeneous phase formulation;
Described wetting agent is that neopelex, Morwet EFW, Terspense4896, nekal, dioctyl sodium sulfosuccinate, tea are withered, one or more any combination in GY-W04, dense breast-500, dense breast-700, NP-10,2201;
Described dispersant is one or more any combination in GY-D06, Morwet D-425, Morwet D-110, terspense 2425, terspense 2700, sodium lignin sulfonate, naphthalenesulfonate condensation compound, alkylnaphthalene sulfonate, sulphonyl succinate, alkylaryl sulfonates, lignosulfonates, CMC, PVA, PVP, XG;
Described antifreezing agent is any combination of a kind of in ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), the third ethanol, glycerine-ether diglycol or two to six kinds;
Described defoamer is organosilicon ketone, polyether silicone, C
8-10fatty alcohol, C
10-20one or more any combination in aliphatic saturated monocarboxylic acid and lipid thereof, polyglycerol, ester-ether type compound;
Described thickener is one or more any combination in polyethylene glycol, xanthan gum, carboxymethyl cellulose, Sodium Polyacrylate, gaseous silicon oxide, bentonite, Magnesiumaluminumsilicate;
Described stabilizing agent is one or more any combination in bentonite, white carbon, lightweight sodium silicate;
Described preservative is one or more any combination in formaldehyde, paraformaldehyde, Sodium Benzoate, benzoic acid;
Described solvent is one or more any combination in water, dimethyl formamide, dimethyl sulfoxide (DMSO), dimethylbenzene, mineral oil, vegetable oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466480.5A CN104970037A (en) | 2015-08-01 | 2015-08-01 | Insecticide compositioncontainingpymetrozine and dinotefuran |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466480.5A CN104970037A (en) | 2015-08-01 | 2015-08-01 | Insecticide compositioncontainingpymetrozine and dinotefuran |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104970037A true CN104970037A (en) | 2015-10-14 |
Family
ID=54267467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510466480.5A Pending CN104970037A (en) | 2015-08-01 | 2015-08-01 | Insecticide compositioncontainingpymetrozine and dinotefuran |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104970037A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475338A (en) * | 2015-12-24 | 2016-04-13 | 安徽美兰农业发展股份有限公司 | Dinotefuran and pymetrozine compound wettable powder and preparation method thereof |
| CN106509000A (en) * | 2016-12-02 | 2017-03-22 | 安徽科立华化工有限公司 | Insecticidal composition containing pymetrozine and dinotefuran as well as preparation method and application of insecticidal composition |
| CN107232222A (en) * | 2017-06-21 | 2017-10-10 | 天峨县平昌生态农业有限公司 | A kind of Pesticidal combination containing pymetrozine and MTI-446 |
| CN113424832A (en) * | 2021-07-02 | 2021-09-24 | 中化化工科学技术研究总院有限公司 | Pymetrozine and dinotefuran dry suspending agent and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632385A (en) * | 2009-08-31 | 2010-01-27 | 江苏辉丰农化股份有限公司 | Insecticidal composition containing pymetrozine |
| CN102228049A (en) * | 2011-06-21 | 2011-11-02 | 尹小根 | Pesticide composition containing dinotefuran and pymetrozine |
| CN102349505A (en) * | 2011-09-13 | 2012-02-15 | 广西田园生化股份有限公司 | Ultra-low-capacity liquid containing dinotefuran |
| CN103385253A (en) * | 2013-08-21 | 2013-11-13 | 陕西康禾立丰生物科技药业有限公司 | Pesticide for killing piercing-sucking type insects and preparation thereof |
| CN103651504A (en) * | 2013-12-04 | 2014-03-26 | 南京农业大学 | Compound insecticide containing dinotefuran and pymetrozine |
| CN104126602A (en) * | 2014-08-18 | 2014-11-05 | 陕西上格之路生物科学有限公司 | Dispersible oil suspending agent containing pymetrozine and dinotefuran |
-
2015
- 2015-08-01 CN CN201510466480.5A patent/CN104970037A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632385A (en) * | 2009-08-31 | 2010-01-27 | 江苏辉丰农化股份有限公司 | Insecticidal composition containing pymetrozine |
| CN102228049A (en) * | 2011-06-21 | 2011-11-02 | 尹小根 | Pesticide composition containing dinotefuran and pymetrozine |
| CN102349505A (en) * | 2011-09-13 | 2012-02-15 | 广西田园生化股份有限公司 | Ultra-low-capacity liquid containing dinotefuran |
| CN103385253A (en) * | 2013-08-21 | 2013-11-13 | 陕西康禾立丰生物科技药业有限公司 | Pesticide for killing piercing-sucking type insects and preparation thereof |
| CN103651504A (en) * | 2013-12-04 | 2014-03-26 | 南京农业大学 | Compound insecticide containing dinotefuran and pymetrozine |
| CN104126602A (en) * | 2014-08-18 | 2014-11-05 | 陕西上格之路生物科学有限公司 | Dispersible oil suspending agent containing pymetrozine and dinotefuran |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475338A (en) * | 2015-12-24 | 2016-04-13 | 安徽美兰农业发展股份有限公司 | Dinotefuran and pymetrozine compound wettable powder and preparation method thereof |
| CN106509000A (en) * | 2016-12-02 | 2017-03-22 | 安徽科立华化工有限公司 | Insecticidal composition containing pymetrozine and dinotefuran as well as preparation method and application of insecticidal composition |
| CN107232222A (en) * | 2017-06-21 | 2017-10-10 | 天峨县平昌生态农业有限公司 | A kind of Pesticidal combination containing pymetrozine and MTI-446 |
| CN113424832A (en) * | 2021-07-02 | 2021-09-24 | 中化化工科学技术研究总院有限公司 | Pymetrozine and dinotefuran dry suspending agent and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102484993B (en) | Synergistic pesticide composition of matrine and tea saponin | |
| CN103271041B (en) | A kind of Compositional type farmland, fruit tree miticide | |
| CN103385251B (en) | A kind of Pesticidal combination of pyriproxyfen-containing | |
| CN103563901A (en) | High-efficient insecticide composition containing propylene glycol alginate | |
| CN103749452B (en) | A kind of seed dressing | |
| CN104970037A (en) | Insecticide compositioncontainingpymetrozine and dinotefuran | |
| CN104982441A (en) | Insecticidal composition containing pymetrozine and nitenpyram and preparation method of insecticidal composition | |
| CN103563950A (en) | Pesticide composition | |
| CN102365969A (en) | Synergetic insecticidal composition containing clothianidin and abamectin | |
| CN102365970A (en) | Synergistic pesticidal composition containing Clothianidin and emamectin benzoate, and its application | |
| CN103430943A (en) | Synergistic kasugamycin composition containing tea saponin | |
| CN106386846A (en) | Insecticidal composition containing clothianidin, chlopyrifos and chlorantraniliprole, and preparation method thereof | |
| CN105010383A (en) | Insecticidal composition containing dinotefuran and indoxacarb and preparation method thereof | |
| CN103563899A (en) | High-efficient pesticide composition | |
| CN106259338A (en) | A kind of containing jasmonic or the composition pesticide of (-)-methyl cis-2-pent-2'-enyl-3-oxocyclopentylacetate | |
| CN102365973A (en) | Synergistic insecticidal composition containing clothianidin and chlopyrifos, and its application | |
| CN105794827A (en) | Insecticidal composition containing spirotetramat | |
| CN103563962A (en) | Insecticide composition containing propylene glycol alginate and anabasine | |
| CN103355309B (en) | Sterilization composition and preparation thereof | |
| CN103563963A (en) | Insecticidal composition containing propylene glycol alginate | |
| CN104488900A (en) | Compound composition containing methanesulphonyl myclobutanil and neonicotinoid insecticide | |
| CN101473828B (en) | Agricultural chemical composition for disinsection and use thereof | |
| CN102907454A (en) | Composite pesticides for controlling rice pests | |
| CN103918718A (en) | Composition containing brevibacillus laterosporus | |
| CN101669502A (en) | Pesticide composition containing chloro-thiazole nicotinoids pesticide and buprofezin as well as preparation and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20151014 |