CN104958540A - Traditional Chinese medicine for treating perennial allergic rhinitis - Google Patents

Traditional Chinese medicine for treating perennial allergic rhinitis Download PDF

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CN104958540A
CN104958540A CN201510445246.4A CN201510445246A CN104958540A CN 104958540 A CN104958540 A CN 104958540A CN 201510445246 A CN201510445246 A CN 201510445246A CN 104958540 A CN104958540 A CN 104958540A
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chinese medicine
radix
allergic rhinitis
perennial allergic
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綦进颜
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Abstract

The invention belongs to the technical field of medicines and in particular relates to a traditional Chinese medicine for treating perennial allergic rhinitis. The traditional Chinese medicine for treating the perennial allergic rhinitis is prepared from the following traditional Chinese medicine raw materials: 11-19 parts of rhizome of ploygonatum cirrhifolium, 6-14 parts of companumoea root, 5-13 parts of mountain celery root, 6-14 parts of berchemia sinica, 5-13 parts of irkutsk anemone rhizome, 5-13 parts of ficus esquiroliana, 2-4 parts of honewort and 4-8 parts of ficus formosana root. When the traditional Chinese medicine provided by the invention is used for treating the perennial allergic rhinitis, effective rate is 52.50%, total effective rate is 93.75%, and no adverse effect is produced.

Description

A kind of Chinese medicine for the treatment of perennial allergic rhinitis
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of perennial allergic rhinitis.
Background technology
Allergic rhinitis (allergic rhinitis, AR) excited by allergen, the I allergic reaction type disease mediated by IgE, its cardinal symptom has nasal obstruction, rhinocnesmus, watery nasal discharge and sneeze, whether to continue according to disease time and fixing, be divided into perennially with seasonal 2 large classes.Doctor trained in Western medicine many employings symptomatic treatment, instant effect, determined curative effect, untoward reaction is many, though can improve the sensitivity of body to a certain extent as desensitization therapy, but can not popularize because holding time short or condition restriction.Therefore, need to find good effect, cost is low, the medicine of the treatment allergic rhinitis that untoward reaction is few.
Summary of the invention
Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine for the treatment of perennial allergic rhinitis.
The present invention is achieved through the following technical solutions:
Treat a perennial allergic rhinitis's Chinese medicine, be made up of the raw material of Chinese medicine medicine of following weight portion:
Rhizoma Polygonati Cirrhifolii 11-19 part, Radix Campanumoeae 6-14 part, mountain celery root 5-13 part, Radix Berchemiae Giraldianae 6-14 part, Rhizoma Anemones Altaicae 5-13 part, Ficus fulva Reinw. 5-13 part, Herba abutili indici 2-4 part, Radix Fici beecheyanae 4-8 part.
Preferably, the Chinese medicine of above-mentioned treatment perennial allergic rhinitis, is made up of the raw material of Chinese medicine medicine of following weight portion:
Rhizoma Polygonati Cirrhifolii 13-17 part, Radix Campanumoeae 8-12 part, mountain celery root 7-11 part, Radix Berchemiae Giraldianae 8-12 part, Rhizoma Anemones Altaicae 7-11 part, Ficus fulva Reinw. 7-11 part, Herba abutili indici 2.5-3.5 part, Radix Fici beecheyanae 5-7 part.
Preferred, the Chinese medicine of above-mentioned treatment perennial allergic rhinitis, is made up of the raw material of Chinese medicine medicine of following weight portion: Rhizoma Polygonati Cirrhifolii 15 parts, Radix Campanumoeae 10 parts, mountain celery root 9 parts, Radix Berchemiae Giraldianae 10 parts, Rhizoma Anemones Altaicae 9 parts, Ficus fulva Reinw. 9 parts, Herba abutili indici 3 parts, Radix Fici beecheyanae 6 parts.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The indication of Chinese medicine of the present invention: be used for the treatment of perennial allergic rhinitis.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
The Chinese prescription mechanism for the treatment of perennial allergic rhinitis of the present invention is as follows:
Rhizoma Polygonati Cirrhifolii another name Radix Stephaniae Cepharanthae, Rhizoma Bergeniae scopulosae, Streptopus simplex D. Don, Caput Gallus domesticus ginseng, Alpinia japonica (Thunb.) Miq., invite alunite.For the rhizome of liliaceous plant polygonatum cirrhifolium Royle.Spring, autumn take rhizome.Nature and flavor are sweet pungent, flat.Function nourishing lung-YIN, invigorating the spleen and benefiting QI, hemostasis of eliminating the phlegm, subduing swelling and detoxicating.Control chronic consumptive disease cough, dizzy, lack of appetite, seminal emission, night sweat, bleeding not during menses, puerperal, body lost, and spitted blood, epistaxis, traumatic hemorrhage, laryngopharynx swelling and pain, and skin ulcer swells, scrofula.
Radix Campanumoeae another name milk ginseng, native Lac caprae seu ovis, white Radix Panacis Quinquefolii, to the moon ginseng, wild codonopsis, Herba Spirodelae ginseng, Radix Talini Paniculati, native Radix Adenophorae (Radix Glehniae), hundred zhang of light, native ginseng, Silene tatarinowii Regel-Melandrium tatarinwiii (Regel) Tsui., Radix Ginseng potatos, moulds step on fruit, Hai Zige, milk starches root, southern Radix Ginseng, Radix Codonopsis Cardiophyllae, river Radix Ginseng, is Campanulaceae Campanumoea javanica Campanumoea jauanica Bl.subop.japonica (Makino) Hong [C.jauanica Bl.var .japonica Makino; C.japonica Maxim.] with the root of leopard Campanumoea jauanica Bl..Sweet in the mouth; Property is put down, and returns spleen; Lung meridian.Function invigorating the spleen and benefiting QI; Tonifying the lung and stopping cough; Stimulating milk secretion.Main asthenia internal injury; The deficiency of vital energy is weak; Cardiopalmus; Hyperhidrosis; Diarrhea due to hypofunction of the spleen; Leucorrhea; Breast is rare; Infantile malnutrition; The enuresis; Cough due to deficiency of the lung.
Mountain celery root is the root on samphire mountain celery Ostericum sieboldii (Miq.).Function delivers loose wind; Damp-clearing pain-relieving.Main headache due to common cold; Rheumatic arthralgia; Soreness of waist and knee joint.
Radix Berchemiae Giraldianae another name cattle a small slice of meat, Radix berchemiae lineatae are the root of Rhamnaceae plant Nasus Bovis seu Bubali fist Berchemia sinica Schneid..Nature and flavor taste is micro-puckery, and property is put down.Function wind-damp dispelling, promoting blood circulation to remove obstruction in the collateral, relieving cough and resolving phlegm, invigorating the spleen and benefiting QI.Dispelling the wind and dampness pathogens arthralgia, lumbago, dysmenorrhea, pulmonary tuberculosis, scrofula, infantile malnutrition, hepatitis, biliary tract ascarid, venom, traumatic injury.
The two bottle prunus mume (sieb.) sieb.et zucc. of Rhizoma Anemones Altaicae another name chrysanthemum shape, Taiyuan Chang, capital Rhizoma Acori Graminei, Shaanxi Chang, Rhizoma Anemones Altaicae, little Rhizoma Acori Graminei.Derive from Ranunculaceae thimbleweed anemone altaica Anemone altaica Mey., be used as medicine with root stock.Pungent, temperature.Function causing resuscitation with aromatic drugs, reduces phlegm, and calms the nerves.Calentura is gone into a coma, and the turbid illiteracy key of expectorant, epilepsy, neurosis, Hiccough and deaf, breast abdominal distention is vexed.External application carbuncle skin ulcer tinea.
The Ficus fulva Reinw. another name tiger palm, crow wind, amnesty mother-in-law tree, hair, derive from moraceae plants Ficus fulva Reinw. Ficus fulva Reiuw., be used as medicine with root bark.Nature and flavor are sweet, flat.Function invigorating the spleen and benefiting QI, promoting blood circulation by removing wind.Curing mainly deficient qi and blood, uterine prolapse, proctoptosis, edema, rheumatic arthralgia, has loose bowels in loose stool.
Herba abutili indici another name ear rings grass, hemp, mill Zhuang fruit, soil rice huller shield, stone grinder is young, the young grass of mill, mill shelves are careless, derives from Malvaceae abutilon plant Herba abutili indici Abutilon indicum (L.) G. Don, is used as medicine with herb or root.Sweet, light, flat.Function wind and heat dispersing, QI invigorating is sensible, diuresis of eliminating the phlegm.For flu, heat of a specified duration is not moved back, mumps, tinnitus, deaf, pulmonary tuberculosis, dysuria.
Radix Fici beecheyanae another name hair Fructus Fici Beecheyanae root is the root of moraceae plants Fructus Fici Beecheyanae Ficus erecta Thumb.var.beecheyana (Hook.et Arn.) King [F.beecheyana Hook.et Arn.].Sweet; Pungent; Warm in nature.Return through lung; Spleen; Kidney channel.Function replenishing QI to invigorate the spleen; Promoting blood circulation to remove obstruction in the collateral; Expelling wind and removing dampness.Main overstrain is weak; Lack of appetite; Agalactia; Insufficiency of the spleen leucorrhea; Proctoptosis; Menoxenia; Wind syndrome of head pain; Traumatic injury; Rheumatic arthralgia.
Allergic rhinitis belong to Chinese medicine " allergic rhinitis " category.Motherland's medical science thinks that the generation of primary disease is mainly due to insufficiency of lung-QI, instability of surface, striae of the skin and muscles being loose, and the heresy of wind and cold, unusual pathogen is taken advantage of a weak point, violate and nose key caused by.But enriching of lung qi, depend on the defeated cloth of temper, taking the photograph of kidney qi is received, therefore primary disease Symptoms is at nose, actually caused by lung qi virtual loss, and has certain relation with spleen kidney.Insufficiency of lung-QI, the heresy criminal of the seizing the opportunity nose of wind and cold, internal injury in lung, struggle between vital QI and pathogen, lattice heresy is gone out, therefore suddenly rhinocnesmus, sneeze are done frequently; Cold-evil holds back lung, impairment of purifying function of the lung, and gas does not take the photograph Tianjin, and Tianjin water is excessive, and thin nasal discharge flows automatically; Poly-obstructed, the hyposmia of then having a stuffy nose of Tianjin water retention.Control when benefiting QI for strengthening the superficies, warming lung for dispelling cold are main.In the Chinese prescription for the treatment of perennial allergic rhinitis of the present invention, the real lung spleen reinforcing of Rhizoma Polygonati Cirrhifolii, Radix Campanumoeae, Radix Fici beecheyanae, benefiting QI for strengthening the superficies; Mountain celery root, Herba abutili indici, Rhizoma Anemones Altaicae wind-expelling pain-stopping, awakening consciousness; Ficus fulva Reinw. promoting blood circulation by removing wind, can cause nose key unimpeded; Convergence that Radix Berchemiae Giraldianae is sour and astringent, reduce nasal mucosa and ooze out, all medicines share the merit of playing benefiting QI for strengthening the superficies, warming lung for dispelling cold altogether, suit allergic rhinitis pathogenesis, so it is very prompt to get effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a perennial allergic rhinitis's Chinese medicine, each crude drug weight proportion is as follows:
Rhizoma Polygonati Cirrhifolii 15g, Radix Campanumoeae 10g, mountain celery root 9g, Radix Berchemiae Giraldianae 10g, Rhizoma Anemones Altaicae 9g, Ficus fulva Reinw. 9g, Herba abutili indici 3g, Radix Fici beecheyanae 6g.
Embodiment 2
Treat a perennial allergic rhinitis's Chinese medicine, each crude drug weight proportion is as follows:
Rhizoma Polygonati Cirrhifolii 13g, Radix Campanumoeae 12g, mountain celery root 7g, Radix Berchemiae Giraldianae 12g, Rhizoma Anemones Altaicae 7g, Ficus fulva Reinw. 11g, Herba abutili indici 2.5g, Radix Fici beecheyanae 7g.
Embodiment 3
Treat a perennial allergic rhinitis's Chinese medicine, each crude drug weight proportion is as follows:
Rhizoma Polygonati Cirrhifolii 17g, Radix Campanumoeae 8g, mountain celery root 11g, Radix Berchemiae Giraldianae 8g, Rhizoma Anemones Altaicae 11g, Ficus fulva Reinw. 7g, Herba abutili indici 3.5g, Radix Fici beecheyanae 5g.
Embodiment 4
Treat a perennial allergic rhinitis's Chinese medicine, each crude drug weight proportion is as follows:
Rhizoma Polygonati Cirrhifolii 11g, Radix Campanumoeae 14g, mountain celery root 5g, Radix Berchemiae Giraldianae 14g, Rhizoma Anemones Altaicae 5g, Ficus fulva Reinw. 13g, Herba abutili indici 2g, Radix Fici beecheyanae 8g.
Embodiment 5
Treat a perennial allergic rhinitis's Chinese medicine, each crude drug weight proportion is as follows:
Rhizoma Polygonati Cirrhifolii 19g, Radix Campanumoeae 6g, mountain celery root 13g, Radix Berchemiae Giraldianae 6g, Rhizoma Anemones Altaicae 13g, Ficus fulva Reinw. 5g, Herba abutili indici 4g, Radix Fici beecheyanae 4g.
Carried out clinical pharrnacokinetics test to the Chinese medicine of embodiments of the invention l, Details as Follows:
1 clinical data
1.1 physical data
In 80 routine patients, man 43 example, female 37 example; The course of disease 12 ~ 24 months 24 examples, 25 ~ 36 months 38 examples, more than 36 months 18 examples, average course of disease 38 months.All cases are and are unsatisfied with and stopping western medical treatment more than 1 month person through therapeutic effect such as doctor trained in Western medicine hormone, antiallergic.
1.2 diagnostic criteria
With reference to otolaryngology branch of Chinese Medical Association to the diagnostic criteria of perennial allergic rhinitis: (1) perennial onset, with sneeze (at every turn continuous more than 3), snivel and tunica mucosa nasi swelling for main clinical manifestation, number of days of falling ill in 1 year is accumulative more than 6 months, and every day, disease time was accumulative more than 0.5h; (2) course of disease at least 1 year.
2. to score standard: clearly inhale personage sensitinogen clue, there is typical sings and symptoms individual and/or family's anaphylactic disease history, stage of attack, respectively count 1 point, totally 3 points.Allergen skin test positive reaction, at least 1 is more than (++) or (++); Specific IgE antibody detects positive or allergen nasal provocation test is positive, and meets with tuerculoderma and medical history, each meter 2 points, totally 4 points.Nasal smear checks that eosinophilic granulocyte is positive and/or nasal mucosa scraping blade mastocyte (basophil) is positive and counts 1 point.Total score 6 ~ 8 points can be diagnosed as the raw allergic rhinitis of normal noon I.
2 Therapeutic Method
Adopt the treatment by Chinese herbs of bold and unrestrained treatment perennial allergic rhinitis.Prescription: Rhizoma Polygonati Cirrhifolii 15g, Radix Campanumoeae 10g, mountain celery root 9g, Radix Berchemiae Giraldianae 10g, Rhizoma Anemones Altaicae 9g, Ficus fulva Reinw. 9g, Herba abutili indici 3g, Radix Fici beecheyanae 6g.L agent in l days, decocting 300 ~ 400mL, point morning, noon and afternoon 3 times are oral.
3 observation of curative effect
3.1 efficacy assessment standard
With reference to otolaryngology branch of Chinese Medical Association surround, Syndrome Scale and sign classification are carried out to the efficacy assessment standard of perennial allergic rhinitis, in table 1, table 2, according to sings and symptoms improvement rate evaluation clinical efficacy after treatment.Improvement rate=(before (before treatment the rear total score of total score-treatment) ÷ treatment total score) × 100%.Improvement rate >50% is effective, and improvement rate 50% ~ 21% is that effectively improvement rate <20% is invalid.
3.2 statistical method
SPSS13.0 software is adopted to carry out statistical procedures.Measurement data adopts mean standard deviation (x ± s) to represent, measurement data adopts t inspection.
3.3 therapeutic outcome
3.3.1 before and after treatment, clinical symptoms compares with somatic feature score: treat front 80 routine patient clinical symptom and sign integrations for (2.35 ± 0.39) point, after treatment be (1.16 ± 0.29) point, integral contrast before and after treatment, difference has statistical significance (P<O.05).
3.3. 2 clinical total effectses: treat after 8 weeks and evaluate short term effect according to integration change: effective 42 examples, account for 52.50%; Effective 33 examples, account for 41.25%; Invalid 5 examples, account for 6.25%, total effective rate accounts for 93.75%.
4. analysis of adverse reactions
In therapeutic process, patient does not all tell uncomfortable situation, has no obvious adverse reaction.Before and after treatment, blood, urine, stool routine and Liver and kidney function detect and are showed no exception.

Claims (3)

1. treat a perennial allergic rhinitis's Chinese medicine, be made up of the raw material of Chinese medicine medicine of following weight portion:
Rhizoma Polygonati Cirrhifolii 11-19 part, Radix Campanumoeae 6-14 part, mountain celery root 5-13 part, Radix Berchemiae Giraldianae 6-14 part, Rhizoma Anemones Altaicae 5-13 part, Ficus fulva Reinw. 5-13 part, Herba abutili indici 2-4 part, Radix Fici beecheyanae 4-8 part.
2. the Chinese medicine for the treatment of perennial allergic rhinitis according to claim 1, is characterized in that, be made up of the raw material of Chinese medicine medicine of following weight portion:
Rhizoma Polygonati Cirrhifolii 13-17 part, Radix Campanumoeae 8-12 part, mountain celery root 7-11 part, Radix Berchemiae Giraldianae 8-12 part, Rhizoma Anemones Altaicae 7-11 part, Ficus fulva Reinw. 7-11 part, Herba abutili indici 2.5-3.5 part, Radix Fici beecheyanae 5-7 part.
3. the Chinese medicine for the treatment of perennial allergic rhinitis according to claim 3, is characterized in that, be made up of the raw material of Chinese medicine medicine of following weight portion:
Rhizoma Polygonati Cirrhifolii 15 parts, Radix Campanumoeae 10 parts, mountain celery root 9 parts, Radix Berchemiae Giraldianae 10 parts, Rhizoma Anemones Altaicae 9 parts, Ficus fulva Reinw. 9 parts, Herba abutili indici 3 parts, Radix Fici beecheyanae 6 parts.
CN201510445246.4A 2015-07-27 2015-07-27 Traditional Chinese medicine for treating perennial allergic rhinitis Pending CN104958540A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770344A (en) * 2016-04-19 2016-07-20 王刚 Traditional Chinese medicine for treating perennial rhinitis

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Publication number Priority date Publication date Assignee Title
CN104771578A (en) * 2015-04-28 2015-07-15 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating allergic rhinitis
CN104784549A (en) * 2015-04-28 2015-07-22 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating allergic rhinitis

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN104771578A (en) * 2015-04-28 2015-07-15 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating allergic rhinitis
CN104784549A (en) * 2015-04-28 2015-07-22 青岛华仁技术孵化器有限公司 Traditional Chinese medicine for treating allergic rhinitis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770344A (en) * 2016-04-19 2016-07-20 王刚 Traditional Chinese medicine for treating perennial rhinitis

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Application publication date: 20151007