CN104940879A - Honeyed bolus for treating phlegmatic hygrosis mixing type chalazion and preparation method thereof - Google Patents

Abstract

The invention discloses a honeyed bolus for treating phlegmatic hygrosis mixing type chalazion. Active ingredients of the medicine comprise, by weight, 15-35 parts of pinellia ternata, 15-35 parts of fresh ginger, 10-25 parts of pericarpium citri reticulatae, 15-30 parts of rhizoma arisaematis, 10-20 parts of loofah sponges, 10-20 parts of lindera thomsonii, 8-16 parts of cinnamomum burmannii, 6-16 parts of rosa multiflora, 6-14 parts of soft-shelled turtle blood, 5-11 parts of ficus lyrata, 2-6 parts of marsdenia longipes, 6-12 parts of trionyx sinensis wiegmann tergum, 6-12 parts of sarcandra glabra, 4-10 parts of laminaria, 4-10 parts of rhizoma atractylodis, 3-9 parts of bighead atractylodes rhizome, 10-24 parts of liquorice, 10-20 parts of beewax and 80-120 parts of chaste honey. The honeyed bolus smells fragrant, tastes sweet and is effective in eliminating the dampness, reducing the phlegm, expelling the wind, removing the cold, promoting the blood circulation, removing the meridian obstruction, resolving the hardness and dissipating the stagnation, a clear and definite therapeutic effect on the phlegmatic hygrosis mixing type chalazion can be achieved, the symptomatic performance is great, the chalazion can be cured quickly, and the relapse is not prone to occurring.

Description

A kind of phlegm-damp for the treatment of mixes honeyed pill of junction type chalazion and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, relate to a kind of medicine for the treatment of chalazion, specifically relate to and a kind ofly treat the honeyed pill that phlegm-damp mixes junction type chalazion, the invention still further relates to the preparation method of said medicine.

Background technology

Chalazion refers in born of the same parents' eyelid and plays nuclearity scleroma, grows up gradually and not red not chronic external oculopathy oculopathy bitterly.The general course of disease is longer, and easily recurs.Be equivalent to the chalazion of western medicine.Because the scleroma of eyelid kernel shape mainly rises because of phlegm-damp resistance knot born of the same parents' eyelid venation, therefore obtain this name, have another name called Verrucosis, chalazion, chalazion etc.

Small-sized and the static person of node, can not treat, what have can disappear certainly, and the person that can certainly disappear does not hinder yet.If form is comparatively large, affects outward appearance, or have eyelid heavily to fall sense, or have diabrosis trend person, be used as treatment.

By Chinese medical discrimination, this disease can divide two kinds of pattern of syndrome, and the phlegm-damp namely without fiery disease mixes junction type and the phlegm-fire stagnation having fiery disease.The former is common pattern of syndrome, and latter is deteriorated case.

(1) the mixed knot of phlegm-damp: be born in inside and outside born of the same parents' eyelid flesh side, have core to swell, thin as the grain of rice or Semen Glycines, very then large as Semen Viciae fabae, superficial, color of the leather is constant, and skin core is not tangent, the movement pushed away, and that touches is harder.Have aubergine or bois de rose protuberance in upset born of the same parents eyelid, the large person of node has pus to fall and slight foreign body sensation, without obvious General Symptoms.Node shaping and development is slow, and the many nothings of tongue arteries and veins are aobvious to be become.

(2) phlegm-fire pent-up: chalazion meibomian cyst sufferings, surface skin is rubescent, and swollen gesture development is very fast, notably dry mouth and throat, red tongue, yellow and greasy fur, slippery and rapid pulse.

Be main mainly with operation clinically, but also have the record of alone Drug therapy.If can the person of dissipation by Drug therapy, then need not impose operation, but at present the effective medicine of generally recognized as safe still be lacked at present for chalazion.Also have the Chinese medicine for the treatment of chalazion at present, but it does not accomplish dialectical treating, therapeutic effect is poor.

Summary of the invention

Problem to be solved by this invention still lacks the effective medicine of generally recognized as safe at present for chalazion, there is provided a kind of honeyed pill for the treatment of chalazion, honeyed pill of the present invention mixes junction type chalazion to phlegm-damp and has clear and definite curative effect, and suiting the medicine to the illness property is strong, can rapid healing chalazion, not easily recur.

To achieve these goals, technical scheme provided by the invention is:

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: Rhizoma Pinelliae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Pericarpium Citri Reticulatae 10-25 part, Rhizoma Arisaematis (processed) 15-30 part, Retinervus Luffae Fructus 10-20 part, Bai Gui 10-20 part, Cortex Cinnamomi Burmannii 8-16 part, white residual flower 6-16 part, Sanguis Trionycis 6-14 part, Caulis et Folium Fici beecheyanae 5-11 part, Radix Marsdeniae Longipedis 2-6 part, Carapax Trionycis 6-12 part, Eucheuma gelatinosum 6-12 part, Thallus Laminariae (Thallus Eckloniae) 4-10 part, Rhizoma Atractylodis 4-10 part, Rhizoma Atractylodis Macrocephalae 3-9 part, Radix Glycyrrhizae 10-24 part, Cera Flava 10-20 part, chaste honey 80-120 part.

Further, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: Rhizoma Pinelliae 20-30 part, Rhizoma Zingiberis Recens 20-30 part, Pericarpium Citri Reticulatae 14-21 part, Rhizoma Arisaematis (processed) 19-26 part, Retinervus Luffae Fructus 12-18 part, Bai Gui 12-18 part, Cortex Cinnamomi Burmannii 10-14 part, white residual flower 8-14 part, Sanguis Trionycis 8-12 part, Caulis et Folium Fici beecheyanae 7-9 part, Radix Marsdeniae Longipedis 3-5 part, Carapax Trionycis 8-10 part, Eucheuma gelatinosum 8-10 part, Thallus Laminariae (Thallus Eckloniae) 6-8 part, Rhizoma Atractylodis 6-8 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Radix Glycyrrhizae 14-20 part, Cera Flava 13-17 part, chaste honey 90-110 part.

Further, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 25 parts, 25 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 17 parts, Rhizoma Arisaematis (processed) 22 parts, Retinervus Luffae Fructus 15 parts, Bai Gui 15 parts, Cortex Cinnamomi Burmannii 12 parts, white residual flower 11 parts, Sanguis Trionycis 10 parts, Caulis et Folium Fici beecheyanae 8 parts, Radix Marsdeniae Longipedis 4 parts, Carapax Trionycis 9 parts, Eucheuma gelatinosum 9 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Rhizoma Atractylodis 7 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, 17 parts, Radix Glycyrrhizae, 15 parts, Cera Flava, chaste honey 100 parts.

The present invention also provides a kind of and treats the preparation method that phlegm-damp mixes the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Pharmacological action:

The Rhizoma Pinelliae: medicinal part is the dry tuber of the aroid Rhizoma Pinelliae.Acrid in the mouth, warm in nature.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For damp-phlegm cold-phlegm, cough with asthma abundant expectoration, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; External treatment carbuncle sucutaneous nodule; Rhizoma Zingiberis Recens: agents area is the dry rhizome of zingiber.Acrid in the mouth, slightly warm in nature.Return lung, spleen, stomach warp.Induce sweat cold expelling, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, removing toxic substances.Cure mainly anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab; Pericarpium Citri Reticulatae: medicinal part is the dry mature skin of rutaceae orange and variety thereof.Bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm; Rhizoma Arisaematis (processed): medicinal part is the dry tuber of aroid Rhizoma Arisaematis, Arisaema heterophyllum B1. or arisaema amurense Maxim.Bitter in the mouth, pungent, warm in nature.Return lung, liver, spleen channel.Drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, mouth eye tiltedly, hemiplegia, epilepsy, infantile convulsion, tetanus; Carbuncle is controlled in external, snake bite and insect sting; Retinervus Luffae Fructus: medicinal part is the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae.Sweet in the mouth, property is put down." book on Chinese herbal medicine is just read ": sweet in the mouth, cold in nature.Return stomach, lung, Liver Channel.Dispel the wind, dredging collateral, invigorates blood circulation, effect of stimulating milk secretion.Be used for the treatment of arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis, acute mastitis swells and ache; Bai Gui: medicinal part is the leaf of the new Camphor tree in Lauraceae new cinnamon Yunnan, root bark or peel of stem.Acrid in the mouth, sweet, warm in nature.Return lung, Liver Channel.Expelling wind and cold, blood circulation promoting and blood stasis dispelling.For cold syndrome of the stomach gastralgia, abdominal distention, rheumatic arthralgia, hemiplegia, dysmenorrhea, menoxenia, anemofrigid cold, measles, traumatic injury, fracture, eczema; Cortex Cinnamomi Burmannii: medicinal part is the cloudy fragrant bark of dicotyledon medicine canella.Bark is containing volatile oil (for cinnamic aldehyde, eugenol, safrole etc.).Bark is containing volatile oil 0.4%-0.6%, and in oil, main constituent is cinnamic aldehyde (77%), eugenol and Sassafras oil brain.Pungent, temperature." south of the Five Ridges gather medicinal herbs record ": " acrid in the mouth." " Luchuan book on Chinese herbal medicine ": " and pungent, temperature." enter spleen channel.Warming middle-JIAO, cold expelling, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling.Control lack of appetite, abdominal distention, have loose bowels, epigastric pain, rheumatism, skin ulcer swells, osteopatia sprain; White residual flower: medicinal part is dried floral or the root of Rosaceae gul powder ball Flos Rosae Multiflorae.Root is containing tannin.Flower is containing aromatic oil.Bitter in the mouth, puckery, cold in nature.Flower: clearing away summer-heat heat, removing dampness is turbid, pleasant stomach function regulating.Root: promoting blood circulation to remove obstruction in the collateral.Flower: uncomfortable in chest for summer-heat, thirsty, vomiting, anorexia, aphtha erosion of the oral mucosa.Root: for arthritis, facial paralysis; External is ground into powder and is applicable to scald; Sanguis Trionycis: sweet in the mouth; Salty; Property is put down.Return Liver Channel.Nourishing YIN and clearing away heat; Promoting blood circulation to remove obstruction in the collateral.Main asthenia hectic fever, deficiency of YIN low grade fever, hypochondriac pain, mouth eye tiltedly, proctoptosis; Caulis et Folium Fici beecheyanae: medicinal part is stem, the leaf of moraceae plants Fructus Fici Beecheyanae.Sweet light, temperature, nontoxic.Enter lung, spleen, kidney three warp.Invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Dispelling the wind and dampness pathogens arthralgia, the middle deficiency of vital energy is weak, and QI and blood is on the decline, and extremity are aching and limp, stiffness of the muscle and joint, traumatic injury, amenorrhea, galactostasis.Exopathogen wind heat person is had to avoid use; Make up a prescription and avoid slender acanthopanax, white Su flower; Radix Marsdeniae Longipedis: Radix Marsdeniae Longipedis is used as medicine with root or Herb.Sweet, micro-hardship, puckery, temperature.Poisonous.Promoting blood circulation and hemostasis, relaxing muscles and tendons and activating QI and blood in the collateral, relieving cough and asthma.For traumatic injury, rheumatalgia, internal hemorrhage, bronchitis, asthma; Fracture is controlled in external, traumatic hemorrhage; Carapax Trionycis: medicinal part is the carapace of Trionychidae animal Trionyx sinensis Wiegmann.Salty in the mouth, cold nature.Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, brings down a fever except steaming, hard masses softening and resolving.For fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, hyperactivity of YANG due to deficiency of YIN, has a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， mass in the abdomen, chronic malaria; Eucheuma gelatinosum: sweet is salty, cold, nontoxic.Return lung, liver, large intestine channel.Removing heat from the lung and dissipating phlegm; Hard masses softening and resolving; Removing toxic substances.Cure mainly phlegm-heat cough, gall subcutaneous nodule, swelling and pain of hemorrhoid or hematochezia, intestinal is scorching; Thallus Laminariae (Thallus Eckloniae): medicinal part is the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) or Alariaceae plant Thallus Laminariae (Thallus Eckloniae).Salty in the mouth, cold in nature.Return liver, stomach, kidney channel.Eliminating phlegm and softening indurated mass eliminating stagnation, inducing diuresis to remove edema.For goiter, scrofula, painful and swollen testis, phlegm retention edema; Rhizoma Atractylodis: the dry rhizome of medicinal part feverfew Atractylodes lancea (Thunb.) DC. or Atractylis chinensis.Acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For retention of dampness in middle-JIAO, distension and fullness in the abdomen, has loose bowels, edema, and beriberi flaccidity is knitted, rheumatic arthralgia, anemofrigid cold, nyctalopia, and eyes dusk is puckery; The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement; Radix Glycyrrhizae: sweet in the mouth, gas is put down, and property is delayed.Enter spleen of Foot-Taiyin, the stomach channel of foot-Yang-ming.Standby punching and positive taste, grasp pure and honest good money, Ru Jin Mu Liangjiazhi circle, return between extreme misery two gas, cultivate Central Region, bring up four other, the panacea of sexual intercourse spirit, tune helps the miracle of QI and blood.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; Cera Flava: medicinal part is the wax of Apidae insecticide apis cerana or apis mellifera Linnaeus secretion.Sweet in the mouth, slightly warm in nature.Return spleen channel.Removing toxic substances, sore, granulation promoting, pain relieving.For ulcer being unable to heal, ecthyma is rotten to the corn, wound ulceration, burn and scald; Chaste honey: the abbreviation being JINGTIAOHUA Mel, is also chaste tree nectar.Its nectarine pool is gorgeous, and be translucent succinum shape; Crystallization exquisiteness is milky white, fragrant, and mouthfeel is agreeably sweet, and concentration is 41 degree ~ 42 degree.In honey containing glucose 32.9%, fructose 41.4%, acidity be 2.13%, enzyme degree is 179%, sugar content is 0.27%, and plants mineral and protein, aminoacid, vitamin, mineral acid etc. containing more than 10.Chaste honey is light amber, and transparency is lower, abnormal smells from the patient delicate fragrance, sweet, the micro-acid of mouthfeel, easy crystallization, and fine and smooth milky after crystallization, is long placed in rear color and luster and increases the weight of.Chaste honey can promote antisecosis, also be very applicable to after meal easily sleepy, physical demands is large, the large person of stress.Improve looks, be healthy and strong, moisturize, removing toxic substances of dispeling the wind, loosening bowel to relieve constipation, facilitating digestion help absorption, appetite promoting and the spleen strengthening, the intestines and stomach coordinating, QI invigorating invigorating middle warmer, diaphoresis heat radiation, the clear order of cold expelling.Be applicable to insufficiency of vital energy and blood, anemogenous headache, conjunctival congestion, insomniac.Informal dress chaste honey, can strengthen human body specificity and non-specific immunity, improves body constitution, to cardiovascular system diseases, as heart tonifying, improves blood circulation aspect and has auxiliary curative effect, have effect of evacuating pus and expelling toxin by reinforcing QI and blood, pain relieving tonify deficiency.

Chinese medicine viewpoint: primary disease is many processs Bo because throwing off restraint food, the raw expectorant of taste intrinsic heat, combination of phlegm and heat, retardance meridians, cause QI and blood being obstructed, form in the hidden born of the same parents' of arising from eyelid.Also have because pinprick in born of the same parents' eyelid does not become pus and limit to, though or pus become and not diabrosis all can transfer primary disease to." the new method gist of Yizong Jinjian ophthalmology " cloud: " card of the raw sucutaneous nodule of spleen, forms because phlegm-fire knot is poly-... "." Zhang Jiechun ophthalmology card control interior take turns illness " is also said: " primary disease claims chalazion ... many by spleen-dampness and stomach-heat, damp-heat gluing each other, poly-and raw expectorant, damp-phlegm blocks meridians, ties and forms in born of the same parents' eyelid ".As can be seen here, assertive evidence is by the pungent delicious food of surfeit, and taste lose to be transported, and wet and be polymerized to expectorant, phlegm-damp hinders in meridians, ties in born of the same parents' eyelid, gradually becomes lump, or phlegm-damp accumulation symptom, strongly fragrant fire-transformation of a specified duration, and phlegm-fire is fought mutually, or caused by attacking outside the mixed heresy tying pathogenic wind toxic of holding concurrently of phlegm-damp.

Based on above-mentioned theory of Chinese medical science, mix junction type chalazion for phlegm-damp, the present invention with drying dampness to eliminate phlegm, expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, hard masses softening and resolving for the rule for the treatment of.With the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae in side, the medicine of Rhizoma Arisaematis (processed) drying dampness to eliminate phlegm is monarch drug, wherein Rhizoma Pinelliae drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, Rhizoma Zingiberis Recens induces sweat cold expelling, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Rhizoma Arisaematis (processed) drying dampness to eliminate phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating, this four Chinese medicine compatibility plays drying dampness to eliminate phlegm altogether, the merit of the cold expelling that induces sweat, Retinervus Luffae Fructus, Bai Gui, Cortex Cinnamomi Burmannii are ministerial drug altogether, wherein Retinervus Luffae Fructus have dispelling wind and removing obstruction in the collateral, the effect of stimulating milk secretion of invigorating blood circulation, white osmanthus expelling wind and cold, blood circulation promoting and blood stasis dispelling, Cortex Cinnamomi Burmannii warming spleen and stomach for dispelling cold, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, plays the merit of warming spleen and stomach for dispelling cold, expelling wind and removing dampness altogether, white residual flower, Sanguis Trionycis, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis are adjuvant drug altogether, wherein white residual flower promoting blood circulation to remove obstruction in the collateral, Sanguis Trionycis nourishing YIN and clearing away heat, promoting blood circulation to remove obstruction in the collateral, Caulis et Folium Fici beecheyanae invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication, Radix Marsdeniae Longipedis promoting blood circulation and hemostasis, relaxing muscles and tendons and activating QI and blood in the collateral, this four Chinese medicine compatibility has the effect of invigorating the spleen for eliminating dampness, promoting blood circulation to remove obstruction in the collateral, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Cera Flava, chaste honey is altogether for making medicine, wherein spleen returned by Rhizoma Atractylodis, stomach, Liver Channel, drying damp and strengthening spleen, expelling wind and cold, spleen returned by the Rhizoma Atractylodis Macrocephalae, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic, Rhizoma Atractylodis and Rhizoma Atractylodis Macrocephalae compatibility can enter spleen by priming, Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, Cera Flava removing toxic substances sore, granulation promoting pain relieving, for there being some cold medicines in side, Radix Glycyrrhizae and Cera Flava energy coordinating the actions of various ingredients in a prescription, chaste honey fragrant, mouthfeel is agreeably sweet, to dispel the wind removing toxic substances, appetite promoting and the spleen strengthening, the intestines and stomach coordinating, QI invigorating invigorating middle warmer, diaphoresis is dispelled the heat, as the binding agent of honeyed pill of the present invention, the present invention is made to have the abnormal smells from the patient of delicate fragrance, sweet mouthfeel.Full side plays the merit of drying dampness to eliminate phlegm, expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, hard masses softening and resolving altogether, more has Rhizoma Atractylodis, Rhizoma Atractylodis Macrocephalae compatibility, all guiding drug medicines can be entered spleen, make all medicines arrive lesions position fast, play drug effect rapidly, taste phlegm-damp is dissipated, disappear stagnant eliminating stagnation, and make the strong fortune of taste, namely sucutaneous nodule disappears.

The invention has the beneficial effects as follows:

(1) the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription meets theory of Chinese medical science and Pharmacopoeia of People's Republic of China requirement, to human non-toxic's side effect, all former spices according to the principle compatibility of monarch together at utmost to play drug effect, play the merit of drying dampness to eliminate phlegm, expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, hard masses softening and resolving altogether, reach the object that treatment phlegm-damp mixes junction type chalazion;

(2) the present invention is prepared into honeyed pill, is binding agent with chaste honey, makes the present invention have the abnormal smells from the patient of delicate fragrance, no matter sweet mouthfeel, be grown up, child all can accept, and add Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, spleen can be entered by priming, energy fast onset drug effect, helps all medicine drying dampness to eliminate phlegm, expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, hard masses softening and resolving, taste heat-phlegm is dissipated, disappear stagnant eliminating stagnation, dredging collateral quench, taste are in harmonious proportion, and namely sucutaneous nodule disappears;

(3) honeyed pill of the present invention determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs in treatment, mixes junction type chalazion clear curative effect for phlegm-damp, and suiting the medicine to the illness property is strong, and Special Nursing in Special Disease is controlled, reliable effect, proves through drug test, and electuary of the present invention has no side effect, can relievedly take, can rapid healing chalazion, not easily recur.

Below by clinical experimental study, beneficial effect of the present invention is further analyzed.

1, clinical data

Inventor accepts the patient that 129 routine phlegm-damp mix junction type chalazion altogether for medical treatment during the May-2015 years 01 months in 2014; age 10-29 year; course of disease 1-6 month; clinical manifestation is for being born in inside and outside born of the same parents' eyelid flesh side; core is had to swell, thin as the grain of rice or Semen Glycines, very then large as Semen Viciae fabae; superficial; color of the leather is constant, and skin core is not tangent, the movement pushed away; that touches is harder; have aubergine or bois de rose protuberance in upset born of the same parents eyelid, the large person of node has pus to fall and slight foreign body sensation, without obvious General Symptoms; node shaping and development is slow, and the many nothings of tongue arteries and veins are aobvious to be become.

2, diagnosis basis

Born of the same parents' eyelid is subcutaneous to be touched circle and to differ in size the scleroma of core shape, press not bitterly, what skin pushed away can move, and the large person's skin surface of core slightly swells, in aubergine in eyelid;

If ulceration voluntarily, discharges colloid substance in eyelid, and granulation can be formed in eyelid;

The little person of core is without discomfort, and the large person of core has and heavily falls sense, if feel exopathogen again, can occur red, swollen, bitterly; If in eyelid the person of wearing out, can cause mill pain.

3, Therapeutic Method

Every day twice, each 15, use warm boiled water.It within one week, is a course for the treatment of.

4, efficacy evaluation

Cure: sucutaneous nodule dissipates, wound healing.

Take a turn for the better: sucutaneous nodule reduces.

Do not heal: sucutaneous nodule size is without change, or recurrent exerbation.

5, therapeutic outcome

After the treatment of four courses for the treatment of, in 129 routine patients, cure 97 examples, take a turn for the better 30 examples, and do not heal 2 examples; Reach 75.19% through statistical analysis cure rate, total effective rate reaches 98.45%, and over the course for the treatment of, has no any untoward reaction or side effect, shows safe and effective for medication.Without recurrence after drug withdrawal.

6, model case

Case 1: Liu, 15 years old, student.The eye face swelling of patient lower-left, foreign body sensation is obvious, has core to swell after 2 days, large as Semen Glycines, painless gargalesthesia, has aubergine or bois de rose protuberance, without other symptoms in upset born of the same parents eyelid.After taking 2 courses for the treatment of of honeyed pill of the present invention, protuberance obviously reduces, and after continuing to take 2 courses for the treatment of, in eye face, protuberance disappears, rehabilitation.Follow up a case by regular visits to and do not recur for 2 years.

Case 2: wear certain, 26 years old, worker.The right UL swelling of patient, foreign body sensation is obvious, has the thin core as the grain of rice to swell, without other symptoms in ULRE.After taking 2 courses for the treatment of of honeyed pill of the present invention, swelling obviously alleviates, and protuberance major part disappears, and after continuing to take 1 course for the treatment of, all symptoms all disappear.Follow up a case by regular visits to and do not recur for 2 years.

Detailed description of the invention

Below in conjunction with embodiments of the invention, technical scheme of the present invention is clearly and completely described.

Embodiment 1

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 15 parts, 15 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 10 parts, Rhizoma Arisaematis (processed) 15 parts, Retinervus Luffae Fructus 10 parts, Bai Gui 10 parts, Cortex Cinnamomi Burmannii 8 parts, white residual flower 6 parts, Sanguis Trionycis 6 parts, Caulis et Folium Fici beecheyanae 5 parts, Radix Marsdeniae Longipedis 2 parts, Carapax Trionycis 6 parts, Eucheuma gelatinosum 6 parts, Thallus Laminariae (Thallus Eckloniae) 4 parts, Rhizoma Atractylodis 4 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, 10 parts, Radix Glycyrrhizae, 10 parts, Cera Flava, chaste honey 80 parts.

Described treatment phlegm-damp mixes the preparation method of the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Embodiment 2

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 35 parts, 35 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 25 parts, Rhizoma Arisaematis (processed) 30 parts, Retinervus Luffae Fructus 20 parts, Bai Gui 20 parts, Cortex Cinnamomi Burmannii 16 parts, white residual flower 16 parts, Sanguis Trionycis 14 parts, Caulis et Folium Fici beecheyanae 11 parts, Radix Marsdeniae Longipedis 6 parts, Carapax Trionycis 12 parts, Eucheuma gelatinosum 12 parts, Thallus Laminariae (Thallus Eckloniae) 10 parts, Rhizoma Atractylodis 10 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, 24 parts, Radix Glycyrrhizae, 20 parts, Cera Flava, chaste honey 120 parts.

Described treatment phlegm-damp mixes the preparation method of the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Embodiment 3

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 20 parts, 20 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 14 parts, Rhizoma Arisaematis (processed) 19 parts, Retinervus Luffae Fructus 12 parts, Bai Gui 12 parts, Cortex Cinnamomi Burmannii 10 parts, white residual flower 8 parts, Sanguis Trionycis 8 parts, Caulis et Folium Fici beecheyanae 7 parts, Radix Marsdeniae Longipedis 3 parts, Carapax Trionycis 8 parts, Eucheuma gelatinosum 8 parts, Thallus Laminariae (Thallus Eckloniae) 6 parts, Rhizoma Atractylodis 6 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, 14 parts, Radix Glycyrrhizae, 13 parts, Cera Flava, chaste honey 90 parts.

Described treatment phlegm-damp mixes the preparation method of the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Embodiment 4

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 30 parts, 30 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 21 parts, Rhizoma Arisaematis (processed) 26 parts, Retinervus Luffae Fructus 18 parts, Bai Gui 18 parts, Cortex Cinnamomi Burmannii 14 parts, white residual flower 14 parts, Sanguis Trionycis 12 parts, Caulis et Folium Fici beecheyanae 9 parts, Radix Marsdeniae Longipedis 5 parts, Carapax Trionycis 10 parts, Eucheuma gelatinosum 10 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Rhizoma Atractylodis 8 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, 20 parts, Radix Glycyrrhizae, 17 parts, Cera Flava, chaste honey 110 parts.

Described treatment phlegm-damp mixes the preparation method of the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Embodiment 5

Treat the honeyed pill that phlegm-damp mixes junction type chalazion, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 25 parts, 25 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 17 parts, Rhizoma Arisaematis (processed) 22 parts, Retinervus Luffae Fructus 15 parts, Bai Gui 15 parts, Cortex Cinnamomi Burmannii 12 parts, white residual flower 11 parts, Sanguis Trionycis 10 parts, Caulis et Folium Fici beecheyanae 8 parts, Radix Marsdeniae Longipedis 4 parts, Carapax Trionycis 9 parts, Eucheuma gelatinosum 9 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Rhizoma Atractylodis 7 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, 17 parts, Radix Glycyrrhizae, 15 parts, Cera Flava, chaste honey 100 parts.

Described treatment phlegm-damp mixes the preparation method of the honeyed pill of junction type chalazion, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.

Embodiment 6

Acute oral toxicity test:

Healthy adult mice 40, male and female half and half, body weight is suitable, all between 18-22g, test fasting in first 16 hours, then honeyed pill warm water of the present invention is washed open and rear mice per os administration by gavage repeatedly to be contaminated, given low is 5000mg (effective ingredient)/kg body weight, then fasting 3-4 days is continued, test rat body situation, diet, drinking-water, body weight increase all normal, do not occur obvious intoxicating phenomenon and the phenomena of mortality, place's post mortem Non Apparent Abnormality, judges that the present invention is to the nontoxic level in the true border of chmice acute Oral toxicity.

Long term toxicity test:

Healthy adult mice 20, body weight 18-22g, honeyed pill of the present invention is ground to mix and feeds to mice in feedstuff, mice amount is 52.8g crude drug/kg/ days, continuous nursing 10 weeks, drug withdrawal detected the hair of decimal, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat after 3 weeks, the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of test mice all has no significant effect, and internal organs naked eyes do not find difference change.Histological indications shows, medication 10 weeks and drug withdrawal are after 3 weeks, and Organs of Mice all without obviously changing, illustrates that the present invention is little to toxicity after mice long-term prescription, does not also have difference reaction, application safety after drug withdrawal.

The above is the preferred embodiment of the present invention; its object is to allow person skilled in the art understand content of the present invention and to be implemented; should be understood that; for those skilled in the art; under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.

Claims (4)

1. treat the honeyed pill that phlegm-damp mixes junction type chalazion for one kind, it is characterized in that, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: Rhizoma Pinelliae 15-35 part, Rhizoma Zingiberis Recens 15-35 part, Pericarpium Citri Reticulatae 10-25 part, Rhizoma Arisaematis (processed) 15-30 part, Retinervus Luffae Fructus 10-20 part, Bai Gui 10-20 part, Cortex Cinnamomi Burmannii 8-16 part, white residual flower 6-16 part, Sanguis Trionycis 6-14 part, Caulis et Folium Fici beecheyanae 5-11 part, Radix Marsdeniae Longipedis 2-6 part, Carapax Trionycis 6-12 part, Eucheuma gelatinosum 6-12 part, Thallus Laminariae (Thallus Eckloniae) 4-10 part, Rhizoma Atractylodis 4-10 part, Rhizoma Atractylodis Macrocephalae 3-9 part, Radix Glycyrrhizae 10-24 part, Cera Flava 10-20 part, chaste honey 80-120 part.

2. a kind ofly as claimed in claim 1 treat the honeyed pill that phlegm-damp mixes junction type chalazion, it is characterized in that, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: Rhizoma Pinelliae 20-30 part, Rhizoma Zingiberis Recens 20-30 part, Pericarpium Citri Reticulatae 14-21 part, Rhizoma Arisaematis (processed) 19-26 part, Retinervus Luffae Fructus 12-18 part, white osmanthus 12-18 part, Cortex Cinnamomi Burmannii 10-14 part, white residual flower 8-14 part, Sanguis Trionycis 8-12 part, Caulis et Folium Fici beecheyanae 7-9 part, Radix Marsdeniae Longipedis 3-5 part, Carapax Trionycis 8-10 part, Eucheuma gelatinosum 8-10 part, Thallus Laminariae (Thallus Eckloniae) 6-8 part, Rhizoma Atractylodis 6-8 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Radix Glycyrrhizae 14-20 part, Cera Flava 13-17 part, chaste honey 90-110 part.

3. a kind ofly as claimed in claim 1 treat the honeyed pill that phlegm-damp mixes junction type chalazion, it is characterized in that, the effective ingredient making honeyed pill is made up of the crude drug of following parts by weight: the Rhizoma Pinelliae 25 parts, 25 parts, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae 17 parts, Rhizoma Arisaematis (processed) 22 parts, Retinervus Luffae Fructus 15 parts, Bai Gui 15 parts, Cortex Cinnamomi Burmannii 12 parts, white residual flower 11 parts, Sanguis Trionycis 10 parts, Caulis et Folium Fici beecheyanae 8 parts, Radix Marsdeniae Longipedis 4 parts, Carapax Trionycis 9 parts, Eucheuma gelatinosum 9 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Rhizoma Atractylodis 7 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, 17 parts, Radix Glycyrrhizae, 15 parts, Cera Flava, chaste honey 100 parts.

4. the treatment phlegm-damp as described in any one of claim 1-3 mixes the preparation method of the honeyed pill of junction type chalazion, it is characterized in that, comprises the following steps:

(1) by Carapax Trionycis with after marmite parching to brown, mix with the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae, Rhizoma Arisaematis (processed), Retinervus Luffae Fructus, Cortex Cinnamomi Burmannii, white residual flower, Caulis et Folium Fici beecheyanae, Radix Marsdeniae Longipedis, Eucheuma gelatinosum, Thallus Laminariae (Thallus Eckloniae), Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae and carry out micronizing, cross 325 mesh sieves, gained siftage is Chinese medicine ultra-fine powder end;

(2) smash white osmanthus to pieces extracting juice, then add Sanguis Trionycis, Cera Flava and suitable quantity of water, stirring and dissolving mix homogeneously, obtain mixing medicine juice;

(3) chaste honey is endured with high heat boil, then change slow fire into endure slowly, be heated endure boil to foam be light red gloss, hands twists with the fingers toughness, then the Chinese medicine ultra-fine powder end that the obtained mixing medicine juice of step (2), step (1) are obtained is added successively, uniform stirring is mediated modulation and is made wet medicine group, wet medicine group is inserted in pellet processing machine the wet ball making every 0.5g;

(4) the wet ball that step (3) is obtained is carried out microwave drying, then by dried medicinal pill package, to obtain final product.