CN104940120A - Process for preparing anti-skin-aging skin moisturizer adopting alfalfa - Google Patents
Process for preparing anti-skin-aging skin moisturizer adopting alfalfa Download PDFInfo
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Abstract
The invention discloses a process for preparing anti-skin-aging skin moisturizer adopting alfalfa. According to the process, the alfalfa, radix astragali, radix ophiopogonis, radix angelicae, radix scutellariae, rhizoma chuanxiong, radix glycyrrhizae, radix pueraiae, manyprickle acanthopanax roots, gynostemma pentaphyllum, angelica sinensis, crocus sativus, polygonum multiflorum, poria cocos, atractylodes macrocephala koidz, common cruculigo rhizome, epimedium and other Chinese herbal medicine are selected, and a technique of ultrasonic-assisted extraction + microbial fermentation + ultrasonic-assisted alcohol extraction is adopted. In this way, the leaching rate of active ingredients of the Chinese herbal medicine is increased, and moreover, the content of superoxide dismutase in the skin moisturizer is increased through fermentation of bifidobacterium bifidum. The skin moisturizer is compounded with catechinic acid, rose essential oil, algal polysaccharides, hyaluronic acid, vitamin C and the like having a skin caring function, the anti-aging and skin caring functions of the skin moisturizer are further improved, and the skin moisturizer has a good application effect and market popularization prospects.
Description
Technical field
The present invention relates to a kind of utilize Herba Medicaginis to prepare anti aging effect skin care liquid technique and preparation method, belong to health and beauty product scope.
Background technology
Aging is that each organ of body engenders the progressive process that hypofunction and reserve capabillity decline along with the continuous increase at age.Skin is the maximum organ of human body, has the effects such as sensation, protection, absorption, metabolism, immunity, secretion, excretion, regulate body temperature.With advancing age, skin also can as other organs of human body miopragia, produce various pathological changes, little by little enter ageing state.The aging of skin is that whole body aging is the most external, the most significantly performance.Therefore prevention and delay skin aging have become current social medical research focus.
Naturally aging of skin is with advancing age and betides the degenerative change of skin texture and physiological function.Chinese medicine is thought: the main cause of skin aging is deficient five internal organs, disorder of QI and blood etc., and by nourishing the five internal organs, QI and blood regulating is the important means of traditional Chinese medical science delay skin aging.The research of Chinese medicine in anti aging effect has the advantage of rich experience and uniqueness.Along with the progressively raising of people's lives, the health care consciousness of people strengthens gradually, and the demand in anti aging effect, skin protection whitening etc. increases day by day, Chinese herbal medicine in this field health promoting product development process in occupation of innate advantage condition.For passing on Chinese medicinal herb culture of long standing and well established, meet the demand of women to anti aging effect skin-protecting face nursing Skin whitening care cosmetics, the present invention chooses the Chinese herbal medicine with effects such as QI invigorating tonification, strengthening the body resistance, develops the herbal health care surfactant with anti aging effect skin-protecting face nursing white-skinned face function.
Rich in vitamin E and tricin in Herba Medicaginis; wherein vitamin E is a kind of antioxidant; tricin also has antioxidation, to the destruction of free radical resisting, can suppress the formation of poisonous lipid peroxide; Cell protection is not destroyed; unsaturated fatty acid is stablized, maintains and organize normal metabolism, increase human body body's immunity, delaying human body caducity; make human body skin health smooth, have good application prospect in skin care field.
Summary of the invention
The object of the present invention is to provide a kind of technique utilizing Herba Medicaginis to prepare anti aging effect skin care liquid.
For achieving the above object, the technical solution used in the present invention is as follows:
The invention provides a kind of technique utilizing Herba Medicaginis to prepare anti aging effect skin care liquid, it is characterized in that the Chinese herbal medicine selected and proportion compatibility thereof are: Herba Medicaginis 30 ~ 50 parts, the Radix Astragali 15 ~ 20 parts, Radix Ophiopogonis 10 ~ 15 parts, the Radix Angelicae Dahuricae 8 ~ 12 parts, Radix Scutellariae 10 ~ 15 parts, Rhizoma Chuanxiong 8 ~ 12 parts, 15 ~ 20 parts, Radix Glycyrrhizae, Radix Puerariae 10 ~ 15 parts, Radix Et Caulis Acanthopanacis Senticosi 10 ~ 15 parts, Herb Gynostemmae Pentaphylli 10 ~ 15 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Stigma Croci 10 ~ 12 parts, Radix Polygoni Multiflori 5 ~ 8 parts, 4 ~ 6 parts, Poria, the Rhizoma Atractylodis Macrocephalae 8 ~ 10 parts, Rhizoma Curculiginis 4 ~ 6 parts, Herba Epimedii 3 ~ 5 parts.
The invention provides one utilizes Herba Medicaginis to prepare anti aging effect skin care liquid, it is characterized in that preparation technology specifically comprises the following steps:
(1) Chinese herbal medicine compatibility: Chinese herbal medicine is sorted, remove and rot and moth person, cleaning is dried, according to the above ratio compatibility Chinese herbal medicine;
(2) pulverize: pulverize after Chinese herbal medicine mixing, cross 100 mesh sieves;
(3) Ultrasonic Wave-Assisted Extraction: be dissolved in by Chinese herbal medicine in 8 ~ 10 times of deionized waters, adds 1 ~ 2% α-amylase, 2 ~ 3% non-starch polysaccharide enzymes, 1 ~ 2% saccharifying enzyme, under 300W ultrasonic assistant condition, and lixiviate 40 ~ 60min, control temperature 40 ~ 60 DEG C;
(4) fermentable: add the bifidobacterium bifidum after 3 ~ 5% activation in lixiviating solution, anaerobic condition bottom fermentation 6 ~ 10h, control fermentation temperature 28 ~ 35 DEG C;
(5) centrifugal: centrifugalize solid residue and supernatant after fermentation ends;
(6) ultrasonic assistant alcohol steep: adding 2 ~ 3 times of concentration in solid residue is the ethanol of 70%, lixiviate 20 ~ 30min under ultrasonic assistant condition, extraction temperature 40 ~ 60 DEG C;
(7) centrifugal: lixiviate terminates rear centrifugalize solid residue and alcohol extract;
(8) concentrated distillation: alcohol extract is concentrated Distillation recovery ethanol;
(9) mix: the alcohol extract after reclaiming ethanol is mixed with fermented supernatant fluid;
(10) composite: in mixed skin care liquid, to add 0.02 ~ 0.03% catechin, 0.3 ~ 0.5% Flos Rosae Rugosae quintessence oil, 1 ~ 2% Sargassum polysaccharides, 0.05 ~ 0.1% hyaluronic acid, 1 ~ 2% vitamin C, 0.5 ~ 1% glycerol, adjustment pH6.0 ~ 7.0;
(11) homogenizing: namely homogenizing obtains the herbal health care surfactant of anti aging effect beauty care whitening on homogenizer.
The invention provides a kind of technique utilizing Herba Medicaginis to prepare anti aging effect skin care liquid, with product of the present invention, safety evaluatio has been carried out to SD rat skin acute toxicity, new zealand rabbit skin irritation and guinea pig skin allergy.Experimental result shows, and product of the present invention, to intact skin non-toxic reaction, has no stimulation to intact skin, to guinea pig skin allergy without obvious effect, proves this product safety avirulence.
The invention provides a kind of technique utilizing Herba Medicaginis to prepare anti aging effect skin care liquid, it is advantageous that: one is the Chinese herbal medicine such as scientific compatibility Herba Medicaginis, the Radix Astragali, Radix Ophiopogonis, the Radix Angelicae Dahuricae, Radix Scutellariae, Rhizoma Chuanxiong, Radix Glycyrrhizae, Radix Puerariae, Radix Et Caulis Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, Radix Angelicae Sinensis, Stigma Croci, Radix Polygoni Multiflori, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Curculiginis, Herba Epimedii, by the synergism between Chinese herbal medicine, play effect of anti aging effect beauty care whitening; Two is that the present invention passes through " Ultrasonic Wave-Assisted Extraction+fermentable+ultrasonic assistant alcohol extraction " technique, not only increase the leaching rate of Chinese herbal medicine active component, in Chinese herbal medicine, Saponin, flavone, alkaloidal extraction ratio are all more than 95%, and are improve the content of superoxide dismutase in skin care liquid by the fermentation of bifidobacterium bifidum; Three is the composite materials such as catechin, Flos Rosae Rugosae quintessence oil, Sargassum polysaccharides, hyaluronic acid, vitamin C with beauty care effect of the present invention, further increases the anti-aging nursing face skin protection white-skinned face function of skin care liquid, has good marketing prospect.
Different Chinese herbal medicine nature and flavor are different, effect also exists huge difference, complicated interaction relationship is there is after different Chinese herbal medicine combinations, and proportioning between Chinese herbal medicine is closer, different ratio also will make monarch relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal.Complicated interaction relationship is there is to each other in the application by Chinese herbal medicine such as Herba Medicaginis, the Radix Astragali, Radix Ophiopogonis, the Radix Angelicae Dahuricae, Radix Scutellariae, Rhizoma Chuanxiong, Radix Glycyrrhizae, Radix Puerariae, Radix Et Caulis Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, Radix Angelicae Sinensis, Stigma Croci, Radix Polygoni Multiflori, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Curculiginis, Herba Epimedii, pass through rational proportion, make the relation generation material alterations of skin care liquid, testing result shows that the total antioxidant capacity of skin care liquid of the present invention is 342.15 ± 13.87U/mL, is significantly higher than level of having reported for work at present.The anti aging effect effect of product of the present invention is verified with mouse animal experiment, mice skin tissue superoxide dismutase (SOD) after the different skin care liquid of mensuration use, glutathion peroxidase (GSH-Px), the indexs such as malonaldehyde (MDA) and hydroxyproline (Hyp), experimental result shows that SOD value is 26.11 ± 4.14, GSH-Px value is 54.28 ± 9.28, MDA value is 0.91 ± 0.09, Hyp value is 2.63 ± 0.38, show that skin care liquid of the present invention has good anti aging effect effect, with blank group difference extremely remarkable (p<0.01), experimental result also shows to change the composition of Chinese herbal medicine or the anti aging effect effect of reduction product more remarkable in regular meeting.
Detailed description of the invention
embodiment 1:
One utilizes Herba Medicaginis to prepare anti aging effect skin care liquid, and concrete preparation process is as follows:
(1) Chinese herbal medicine compatibility: Chinese herbal medicine is sorted, remove and rot and moth person, cleaning is dried, in Herba Medicaginis 50 parts, the Radix Astragali 15 parts, Radix Ophiopogonis 15 parts, the Radix Angelicae Dahuricae 8 parts, Radix Scutellariae 15 parts, Rhizoma Chuanxiong 8 parts, 20 parts, Radix Glycyrrhizae, Radix Puerariae 10 parts, Radix Et Caulis Acanthopanacis Senticosi 15 parts, Herb Gynostemmae Pentaphylli 10 parts, Radix Angelicae Sinensis 20 parts, Stigma Croci 10 parts, Radix Polygoni Multiflori 8 parts, 4 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, Rhizoma Curculiginis 4 parts, Herba Epimedii 5 parts of ratio compatibility Chinese herbal medicine;
(2) pulverize: pulverize after Chinese herbal medicine mixing, cross 100 mesh sieves;
(3) Ultrasonic Wave-Assisted Extraction: be dissolved in by Chinese herbal medicine in 10 times of deionized waters, adds 2% α-amylase, 3% non-starch polysaccharide enzyme, 2% saccharifying enzyme, under 300W ultrasonic assistant condition, and lixiviate 40min, control temperature 40 ~ 60 DEG C;
(4) fermentable: add the bifidobacterium bifidum after 5% activation in lixiviating solution, anaerobic condition bottom fermentation 6h, controls fermentation temperature 28 ~ 35 DEG C;
(5) centrifugal: centrifugalize solid residue and supernatant after fermentation ends;
(6) ultrasonic assistant alcohol steep: adding 3 times of concentration in solid residue is the ethanol of 70%, lixiviate 20min under ultrasonic assistant condition, extraction temperature 40 ~ 60 DEG C;
(7) centrifugal: lixiviate terminates rear centrifugalize solid residue and alcohol extract;
(8) concentrated distillation: alcohol extract is concentrated Distillation recovery ethanol;
(9) mix: the alcohol extract after reclaiming ethanol is mixed with fermented supernatant fluid;
(10) composite: in mixed skin care liquid, to add 0.03% catechin, 0.5% Flos Rosae Rugosae quintessence oil, 2% Sargassum polysaccharides, 0.1% hyaluronic acid, 2% vitamin C, 1% glycerol, adjustment pH6.0 ~ 7.0;
(11) homogenizing: namely homogenizing obtains the herbal health care surfactant of anti aging effect beauty care whitening on homogenizer.
embodiment 2:
One utilizes Herba Medicaginis to prepare anti aging effect skin care liquid, and concrete preparation process is as follows:
(1) Chinese herbal medicine compatibility: Chinese herbal medicine is sorted, remove and rot and moth person, cleaning is dried, in Herba Medicaginis 40 parts, the Radix Astragali 18 parts, Radix Ophiopogonis 12 parts, the Radix Angelicae Dahuricae 10 parts, Radix Scutellariae 12 parts, Rhizoma Chuanxiong 10 parts, 18 parts, Radix Glycyrrhizae, Radix Puerariae 13 parts, Radix Et Caulis Acanthopanacis Senticosi 12 parts, Herb Gynostemmae Pentaphylli 13 parts, Radix Angelicae Sinensis 18 parts, Stigma Croci 111 parts, Radix Polygoni Multiflori 6 parts, 5 parts, Poria, the Rhizoma Atractylodis Macrocephalae 9 parts, Rhizoma Curculiginis 5 parts, Herba Epimedii 4 parts of ratio compatibility Chinese herbal medicine;
(2) pulverize: pulverize after Chinese herbal medicine mixing, cross 100 mesh sieves;
(3) Ultrasonic Wave-Assisted Extraction: be dissolved in by Chinese herbal medicine in 9 times of deionized waters, adds 1.5% α-amylase, 2.5% non-starch polysaccharide enzyme, 1.5% saccharifying enzyme, under 300W ultrasonic assistant condition, and lixiviate 50min, control temperature 40 ~ 60 DEG C;
(4) fermentable: add the bifidobacterium bifidum after 4% activation in lixiviating solution, anaerobic condition bottom fermentation 8h, controls fermentation temperature 28 ~ 35 DEG C;
(5) centrifugal: centrifugalize solid residue and supernatant after fermentation ends;
(6) ultrasonic assistant alcohol steep: adding 2.5 times of concentration in solid residue is the ethanol of 70%, lixiviate 25min under ultrasonic assistant condition, extraction temperature 40 ~ 60 DEG C;
(7) centrifugal: lixiviate terminates rear centrifugalize solid residue and alcohol extract;
(8) concentrated distillation: alcohol extract is concentrated Distillation recovery ethanol;
(9) mix: the alcohol extract after reclaiming ethanol is mixed with fermented supernatant fluid;
(10) composite: in mixed skin care liquid, to add 0.025% catechin, 0.4% Flos Rosae Rugosae quintessence oil, 1.5% Sargassum polysaccharides, 0.08% hyaluronic acid, 1.5% vitamin C, 0.8% glycerol, adjustment pH6.0 ~ 7.0;
(11) homogenizing: namely homogenizing obtains the herbal health care surfactant of anti aging effect beauty care whitening on homogenizer.
embodiment 3:
One utilizes Herba Medicaginis to prepare anti aging effect skin care liquid, and concrete preparation process is as follows:
(1) Chinese herbal medicine compatibility: Chinese herbal medicine is sorted, remove and rot and moth person, cleaning is dried, in Herba Medicaginis 30 parts, the Radix Astragali 20 parts, Radix Ophiopogonis 10 parts, the Radix Angelicae Dahuricae 12 parts, Radix Scutellariae 10 parts, Rhizoma Chuanxiong 12 parts, 15 parts, Radix Glycyrrhizae, Radix Puerariae 15 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Herb Gynostemmae Pentaphylli 15 parts, Radix Angelicae Sinensis 15 parts, Stigma Croci 12 parts, Radix Polygoni Multiflori 5 parts, 6 parts, Poria, the Rhizoma Atractylodis Macrocephalae 8 parts, Rhizoma Curculiginis 6 parts, Herba Epimedii 3 parts of ratio compatibility Chinese herbal medicine;
(2) pulverize: pulverize after Chinese herbal medicine mixing, cross 100 mesh sieves;
(3) Ultrasonic Wave-Assisted Extraction: be dissolved in by Chinese herbal medicine in 8 times of deionized waters, adds 1% α-amylase, 2% non-starch polysaccharide enzyme, 1% saccharifying enzyme, under 300W ultrasonic assistant condition, and lixiviate 60min, control temperature 40 ~ 60 DEG C;
(4) fermentable: add the bifidobacterium bifidum after 3% activation in lixiviating solution, anaerobic condition bottom fermentation 10h, controls fermentation temperature 28 ~ 35 DEG C;
(5) centrifugal: centrifugalize solid residue and supernatant after fermentation ends;
(6) ultrasonic assistant alcohol steep: adding 2 times of concentration in solid residue is the ethanol of 70%, lixiviate 30min under ultrasonic assistant condition, extraction temperature 40 ~ 60 DEG C;
(7) centrifugal: lixiviate terminates rear centrifugalize solid residue and alcohol extract;
(8) concentrated distillation: alcohol extract is concentrated Distillation recovery ethanol;
(9) mix: the alcohol extract after reclaiming ethanol is mixed with fermented supernatant fluid;
(10) composite: in mixed skin care liquid, to add 0.02% catechin, 0.3% Flos Rosae Rugosae quintessence oil, 1% Sargassum polysaccharides, 0.05% hyaluronic acid, 1% vitamin C, 0.5% glycerol, adjustment pH6.0 ~ 7.0;
(11) homogenizing: namely homogenizing obtains the herbal health care surfactant of anti aging effect beauty care whitening on homogenizer.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (1)
1. utilize Herba Medicaginis to prepare an anti aging effect skin care liquid, it is characterized in that preparation technology specifically comprises the following steps:
(1) Chinese herbal medicine compatibility: Chinese herbal medicine is sorted, remove and rot and moth person, cleaning is dried, in Herba Medicaginis 30 ~ 50 parts, the Radix Astragali 15 ~ 20 parts, Radix Ophiopogonis 10 ~ 15 parts, the Radix Angelicae Dahuricae 8 ~ 12 parts, Radix Scutellariae 10 ~ 15 parts, Rhizoma Chuanxiong 8 ~ 12 parts, 15 ~ 20 parts, Radix Glycyrrhizae, Radix Puerariae 10 ~ 15 parts, Radix Et Caulis Acanthopanacis Senticosi 10 ~ 15 parts, Herb Gynostemmae Pentaphylli 10 ~ 15 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Stigma Croci 10 ~ 12 parts, Radix Polygoni Multiflori 5 ~ 8 parts, 4 ~ 6 parts, Poria, the Rhizoma Atractylodis Macrocephalae 8 ~ 10 parts, Rhizoma Curculiginis 4 ~ 6 parts, Herba Epimedii 3 ~ 5 parts of ratio compatibility Chinese herbal medicine;
(2) pulverize: pulverize after Chinese herbal medicine mixing, cross 100 mesh sieves;
(3) Ultrasonic Wave-Assisted Extraction: be dissolved in by Chinese herbal medicine in 8 ~ 10 times of deionized waters, adds 1 ~ 2% α-amylase, 2 ~ 3% non-starch polysaccharide enzymes, 1 ~ 2% saccharifying enzyme, under 300W ultrasonic assistant condition, and lixiviate 40 ~ 60min, control temperature 40 ~ 60 DEG C;
(4) fermentable: add the bifidobacterium bifidum after 3 ~ 5% activation in lixiviating solution, anaerobic condition bottom fermentation 6 ~ 10h, control fermentation temperature 28 ~ 35 DEG C;
(5) centrifugal: centrifugalize solid residue and supernatant after fermentation ends;
(6) ultrasonic assistant alcohol steep: adding 2 ~ 3 times of concentration in solid residue is the ethanol of 70%, lixiviate 20 ~ 30min under ultrasonic assistant condition, extraction temperature 40 ~ 60 DEG C;
(7) centrifugal: lixiviate terminates rear centrifugalize solid residue and alcohol extract;
(8) concentrated distillation: alcohol extract is concentrated Distillation recovery ethanol;
(9) mix: the alcohol extract after reclaiming ethanol is mixed with fermented supernatant fluid;
(10) composite: in mixed skin care liquid, to add 0.02 ~ 0.03% catechin, 0.3 ~ 0.5% Flos Rosae Rugosae quintessence oil, 1 ~ 2% Sargassum polysaccharides, 0.05 ~ 0.1% hyaluronic acid, 1 ~ 2% vitamin C, 0.5 ~ 1% glycerol, adjustment pH6.0 ~ 7.0;
(11) homogenizing: namely homogenizing obtains the herbal health care surfactant of anti aging effect beauty care whitening on homogenizer.
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