CN110664677A - Preparation method of composition with anti-saccharification and anti-skin-aging functions - Google Patents

Preparation method of composition with anti-saccharification and anti-skin-aging functions Download PDF

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CN110664677A
CN110664677A CN201910926272.7A CN201910926272A CN110664677A CN 110664677 A CN110664677 A CN 110664677A CN 201910926272 A CN201910926272 A CN 201910926272A CN 110664677 A CN110664677 A CN 110664677A
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parts
radix
skin
extract
composition
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王英
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a preparation method of a composition with saccharification resistance and skin aging resistance, which is characterized by being prepared from the following raw materials in parts by weight: 4-8 parts of astragalus membranaceus, 4-6 parts of radix ophiopogonis, 2-4 parts of radix angelicae, 6-10 parts of ligusticum wallichii, 4-8 parts of liquorice, 2-4 parts of radix puerariae, 2-4 parts of dendrobe, 4-6 parts of polygonum multiflorum, 2-4 parts of poria cocos, 6-8 parts of bighead atractylodes rhizome, 8-10 parts of saffron crocus, 6-8 parts of rhodiola rosea, 2-4 parts of stevia rebaudiana, 4-6 parts of apple fruit cell extract and 2-8 parts of oriental cherry extract. The preparation is simple, can effectively utilize the epigenetic factors of the plant stem cells to maintain the efficacy of the skin, effectively leads the epidermis to be expressed back to a young state, and eliminates the glycated protein.

Description

Preparation method of composition with anti-saccharification and anti-skin-aging functions
Technical Field
The invention relates to the field of preparation of skin care products, in particular to a preparation method of a composition with anti-saccharification and anti-skin-aging functions.
Background
At present, the skin care products on the market have various types and different efficacies, including whitening, moisturizing, freckle removing, aging resisting and the like. However, many products are added with a few chemical substances which are harmful to human bodies, and although the substances have skin care effects of short-term whitening, anti-aging and the like on human skin, if the substances are used for a long time, the skin is seriously damaged, and acne, color spots, lipid secretion disorder and the like appear; the imitation house skin care products contain a plurality of plant extracts, however, in the personal care products, the skin care products using the plant extracts as active substances are more than hundreds of skin care products, the effect brought by the personal care products is more perfect in the field of plant extraction sources according to the development of extraction modes or biotechnology, and further, the plant cell extracts are still few in types, and the living pressure of people is increasingly tense and increased in response to climate change, so that the skin barrier moisturizing function is low.
Disclosure of Invention
In view of the above-mentioned disadvantages of the prior art, the present invention provides a method for preparing a composition having anti-glycation and anti-skin aging effects, which is simple to prepare, can effectively utilize epigenetic factors of plant stem cells to maintain skin efficacy, effectively return epidermis to a young state, and eliminate glycated proteins.
In order to achieve the aim of the invention, the invention adopts the specific scheme that:
a preparation method of a composition with saccharification resisting and skin aging resisting functions comprises the following raw materials in parts by weight: 4-8 parts of astragalus membranaceus, 4-6 parts of radix ophiopogonis, 2-4 parts of radix angelicae, 6-10 parts of ligusticum wallichii, 4-8 parts of liquorice, 2-4 parts of radix puerariae, 2-4 parts of dendrobe, 4-6 parts of polygonum multiflorum, 2-4 parts of poria cocos, 6-8 parts of bighead atractylodes rhizome, 8-10 parts of saffron crocus, 6-8 parts of rhodiola rosea, 2-4 parts of stevia rebaudiana, 4-6 parts of apple fruit cell extract and 2-8 parts of oriental cherry extract.
Further, the method for preparing the anti-glycation and anti-skin-aging composition comprises the following steps:
(1) sorting the Chinese medicinal herbs, removing rotten and moth, cleaning and drying;
(2) mixing radix astragali, radix Ophiopogonis, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Glycyrrhrizae radix, radix Puerariae, herba Dendrobii, Polygoni Multiflori radix, Poria, Atractylodis rhizoma, stigma croci Sativi, radix Rhodiolae, and sweet stevia, pulverizing, and sieving with 200-mesh and 300-mesh sieve;
(3) ultrasonic-assisted extraction: dissolving the crushed mixture obtained in the step (2) in 6-8 times of deionized water, adding 1-2% of alpha-amylase, 2-3% of non-starch polysaccharide enzyme and 1-2% of saccharifying enzyme, leaching for 40-60min under the auxiliary condition of 300W ultrasonic waves, and controlling the temperature to be 40-60 ℃;
(4) and (3) microbial fermentation: adding 3-5% of activated Bifidobacterium bifidum into the leaching solution, fermenting for 6-10h under anaerobic condition, and controlling fermentation temperature to be 28-35 ℃;
(5) centrifuging: centrifugally separating solid residues from supernatant after fermentation;
(6) ultrasonic-assisted ethanol extraction: adding 2-3 times of 65-75% ethanol into the solid residue, and leaching under ultrasonic wave assisted condition for 20-30min at 40-60 deg.C;
(7) centrifuging: centrifugally separating solid residue and alcohol extract after the extraction is finished;
(8) concentration and distillation: concentrating and distilling the alcohol extract to recover ethanol;
(9) mixing: mixing the ethanol extract obtained after ethanol recovery with the fermentation supernatant;
(10) compounding: adding apple fruit cell extract, cherry blossom extract, algal polysaccharides, hyaluronic acid, vitamin C and glycerol into the mixed skin lotion, and adjusting the pH value to be neutral;
(11) homogenizing: homogenizing in homogenizer to obtain composition with anti-glycation and anti-skin aging effects.
The invention has the beneficial effects that:
the Chinese herbal medicines such as astragalus, radix ophiopogonis, radix angelicae, ligusticum wallichii, liquorice, radix puerariae, dendrobe, polygonum multiflorum, poria cocos and bighead atractylodes rhizome have the effects of resisting skin aging, beautifying, protecting skin and whitening through the synergistic effect of the Chinese herbal medicines, the leaching rate of active ingredients of the Chinese herbal medicines is improved through the process of ultrasonic-assisted leaching, microbial fermentation and ultrasonic-assisted alcohol extraction, and the content of superoxide dismutase in the skin care liquid is improved through the fermentation of bifidobacterium bifidum; the skin care lotion has the functions of resisting aging, beautifying, protecting skin and whitening, and can effectively utilize epigenetic factors of plant stem cells to maintain the skin, effectively make the epidermis return to a young state and eliminate glycated proteins.
Detailed Description
The present invention is further described below by way of specific examples, but the present invention is not limited to only the following examples. Variations, combinations, or substitutions of the invention, which are within the scope of the invention or the spirit, scope of the invention, will be apparent to those of skill in the art and are within the scope of the invention.
Example 1: a preparation method of a composition with saccharification resisting and skin aging resisting functions comprises the following raw materials in parts by weight: 4 parts of astragalus membranaceus, 4 parts of radix ophiopogonis, 2 parts of radix angelicae, 6 parts of ligusticum wallichii, 4 parts of liquorice, 2 parts of radix puerariae, 2 parts of dendrobe, 4 parts of polygonum multiflorum, 2 parts of poria cocos, 6 parts of bighead atractylodes rhizome, 8 parts of saffron crocus, 6 parts of rhodiola rosea, 2 parts of stevia rebaudiana, 4 parts of apple fruit cell extract and 2 parts of oriental cherry extract.
The preparation method of the anti-saccharification and anti-skin-aging composition comprises the following steps:
(1) sorting the Chinese medicinal herbs, removing rotten and moth, cleaning and drying;
(2) mixing radix astragali, radix Ophiopogonis, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Glycyrrhrizae radix, radix Puerariae, herba Dendrobii, Polygoni Multiflori radix, Poria, Atractylodis rhizoma, stigma croci Sativi, radix Rhodiolae, and sweet stevia, pulverizing, and sieving with 200 mesh sieve;
(3) ultrasonic-assisted extraction: dissolving the crushed mixture obtained in the step (2) in 6-8 times of deionized water, adding 1-2% of alpha-amylase, 2-3% of non-starch polysaccharide enzyme and 1-2% of saccharifying enzyme, leaching for 40-60min under the auxiliary condition of 300W ultrasonic waves, and controlling the temperature to be 40-60 ℃;
(4) and (3) microbial fermentation: adding 3-5% of activated Bifidobacterium bifidum into the leaching solution, fermenting for 6-10h under anaerobic condition, and controlling fermentation temperature to be 28-35 ℃;
(5) centrifuging: centrifugally separating solid residues from supernatant after fermentation;
(6) ultrasonic-assisted ethanol extraction: adding 2-3 times of 65-75% ethanol into the solid residue, and leaching under ultrasonic wave assisted condition for 20-30min at 40-60 deg.C;
(7) centrifuging: centrifugally separating solid residue and alcohol extract after the extraction is finished;
(8) concentration and distillation: concentrating and distilling the alcohol extract to recover ethanol;
(9) mixing: mixing the ethanol extract obtained after ethanol recovery with the fermentation supernatant;
(10) compounding: adding apple fruit cell extract, cherry blossom extract, algal polysaccharides, hyaluronic acid, vitamin C and glycerol into the mixed skin lotion, and adjusting the pH value to be neutral;
(11) homogenizing: homogenizing in homogenizer to obtain composition with anti-glycation and anti-skin aging effects.
Example 2: a preparation method of a composition with saccharification resisting and skin aging resisting functions comprises the following raw materials in parts by weight: 6 parts of astragalus membranaceus, 5 parts of radix ophiopogonis, 3 parts of radix angelicae, 8 parts of ligusticum wallichii, 6 parts of liquorice, 3 parts of radix puerariae, 3 parts of dendrobe, 5 parts of polygonum multiflorum, 3 parts of poria cocos, 7 parts of bighead atractylodes rhizome, 9 parts of saffron crocus, 7 parts of rhodiola rosea, 3 parts of stevia rebaudiana, 5 parts of apple fruit cell extract and 5 parts of oriental cherry extract.
The preparation method of the anti-saccharification and anti-skin-aging composition comprises the following steps:
(1) sorting the Chinese medicinal herbs, removing rotten and moth, cleaning and drying;
(2) mixing radix astragali, radix Ophiopogonis, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Glycyrrhrizae radix, radix Puerariae, herba Dendrobii, Polygoni Multiflori radix, Poria, Atractylodis rhizoma, stigma croci Sativi, radix Rhodiolae, and sweet stevia, pulverizing, and sieving with 200-mesh and 300-mesh sieve;
(3) ultrasonic-assisted extraction: dissolving the crushed mixture obtained in the step (2) in 6-8 times of deionized water, adding 1-2% of alpha-amylase, 2-3% of non-starch polysaccharide enzyme and 1-2% of saccharifying enzyme, leaching for 40-60min under the auxiliary condition of 300W ultrasonic waves, and controlling the temperature to be 40-60 ℃;
(4) and (3) microbial fermentation: adding 3-5% of activated Bifidobacterium bifidum into the leaching solution, fermenting for 6-10h under anaerobic condition, and controlling fermentation temperature to be 28-35 ℃;
(5) centrifuging: centrifugally separating solid residues from supernatant after fermentation;
(6) ultrasonic-assisted ethanol extraction: adding 2-3 times of 65-75% ethanol into the solid residue, and leaching under ultrasonic wave assisted condition for 20-30min at 40-60 deg.C;
(7) centrifuging: centrifugally separating solid residue and alcohol extract after the extraction is finished;
(8) concentration and distillation: concentrating and distilling the alcohol extract to recover ethanol;
(9) mixing: mixing the ethanol extract obtained after ethanol recovery with the fermentation supernatant;
(10) compounding: adding apple fruit cell extract, cherry blossom extract, algal polysaccharides, hyaluronic acid, vitamin C and glycerol into the mixed skin lotion, and adjusting the pH value to be neutral;
(11) homogenizing: homogenizing in homogenizer to obtain composition with anti-glycation and anti-skin aging effects.
Example 3: a preparation method of a composition with saccharification resisting and skin aging resisting functions comprises the following raw materials in parts by weight: 8 parts of astragalus membranaceus, 6 parts of radix ophiopogonis, 4 parts of radix angelicae, 10 parts of ligusticum wallichii, 8 parts of liquorice, 4 parts of radix puerariae, 4 parts of dendrobe, 6 parts of polygonum multiflorum, 4 parts of poria cocos, 8 parts of bighead atractylodes rhizome, 10 parts of saffron crocus, 8 parts of rhodiola rosea, 4 parts of stevia rebaudiana, 6 parts of apple fruit cell extract and 8 parts of oriental cherry extract.
2. The method for preparing the composition with anti-glycation and anti-skin-aging effects as claimed in claim 1, wherein the method for preparing the composition with anti-glycation and anti-skin-aging effects comprises the following steps:
(1) sorting the Chinese medicinal herbs, removing rotten and moth, cleaning and drying;
(2) mixing radix astragali, radix Ophiopogonis, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Glycyrrhrizae radix, radix Puerariae, herba Dendrobii, Polygoni Multiflori radix, Poria, Atractylodis rhizoma, stigma croci Sativi, radix Rhodiolae, and sweet stevia, pulverizing, and sieving with 200-mesh and 300-mesh sieve;
(3) ultrasonic-assisted extraction: dissolving the crushed mixture obtained in the step (2) in 6-8 times of deionized water, adding 1-2% of alpha-amylase, 2-3% of non-starch polysaccharide enzyme and 1-2% of saccharifying enzyme, leaching for 40-60min under the auxiliary condition of 300W ultrasonic waves, and controlling the temperature to be 40-60 ℃;
(4) and (3) microbial fermentation: adding 3-5% of activated Bifidobacterium bifidum into the leaching solution, fermenting for 6-10h under anaerobic condition, and controlling fermentation temperature to be 28-35 ℃;
(5) centrifuging: centrifugally separating solid residues from supernatant after fermentation;
(6) ultrasonic-assisted ethanol extraction: adding 2-3 times of 65-75% ethanol into the solid residue, and leaching under ultrasonic wave assisted condition for 20-30min at 40-60 deg.C;
(7) centrifuging: centrifugally separating solid residue and alcohol extract after the extraction is finished;
(8) concentration and distillation: concentrating and distilling the alcohol extract to recover ethanol;
(9) mixing: mixing the ethanol extract obtained after ethanol recovery with the fermentation supernatant;
(10) compounding: adding apple fruit cell extract, cherry blossom extract, algal polysaccharides, hyaluronic acid, vitamin C and glycerol into the mixed skin lotion, and adjusting the pH value to be neutral;
(11) homogenizing: homogenizing in homogenizer to obtain composition with anti-glycation and anti-skin aging effects.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (2)

1. A preparation method of a composition with anti-saccharification and anti-skin-aging functions is characterized by being prepared from the following raw materials in parts by weight: 4-8 parts of astragalus membranaceus, 4-6 parts of radix ophiopogonis, 2-4 parts of radix angelicae, 6-10 parts of ligusticum wallichii, 4-8 parts of liquorice, 2-4 parts of radix puerariae, 2-4 parts of dendrobe, 4-6 parts of polygonum multiflorum, 2-4 parts of poria cocos, 6-8 parts of bighead atractylodes rhizome, 8-10 parts of saffron crocus, 6-8 parts of rhodiola rosea, 2-4 parts of stevia rebaudiana, 4-6 parts of apple fruit cell extract and 2-8 parts of oriental cherry extract.
2. The method for preparing the composition with anti-glycation and anti-skin-aging effects as claimed in claim 1, wherein the method for preparing the composition with anti-glycation and anti-skin-aging effects comprises the following steps:
(1) sorting the Chinese medicinal herbs, removing rotten and moth, cleaning and drying;
(2) mixing radix astragali, radix Ophiopogonis, radix Angelicae Dahuricae, rhizoma Ligustici Chuanxiong, Glycyrrhrizae radix, radix Puerariae, herba Dendrobii, Polygoni Multiflori radix, Poria, Atractylodis rhizoma, stigma croci Sativi, radix Rhodiolae, and sweet stevia, pulverizing, and sieving with 200-mesh and 300-mesh sieve;
(3) ultrasonic-assisted extraction: dissolving the crushed mixture obtained in the step (2) in 6-8 times of deionized water, adding 1-2% of alpha-amylase, 2-3% of non-starch polysaccharide enzyme and 1-2% of saccharifying enzyme, leaching for 40-60min under the auxiliary condition of 300W ultrasonic waves, and controlling the temperature to be 40-60 ℃;
(4) and (3) microbial fermentation: adding 3-5% of activated Bifidobacterium bifidum into the leaching solution, fermenting for 6-10h under anaerobic condition, and controlling fermentation temperature to be 28-35 ℃;
(5) centrifuging: centrifugally separating solid residues from supernatant after fermentation;
(6) ultrasonic-assisted ethanol extraction: adding 2-3 times of 65-75% ethanol into the solid residue, and leaching under ultrasonic wave assisted condition for 20-30min at 40-60 deg.C;
(7) centrifuging: centrifugally separating solid residue and alcohol extract after the extraction is finished;
(8) concentration and distillation: concentrating and distilling the alcohol extract to recover ethanol;
(9) mixing: mixing the ethanol extract obtained after ethanol recovery with the fermentation supernatant;
(10) compounding: adding apple fruit cell extract, cherry blossom extract, algal polysaccharides, hyaluronic acid, vitamin C and glycerol into the mixed skin lotion, and adjusting the pH value to be neutral;
(11) homogenizing: homogenizing in homogenizer to obtain composition with anti-glycation and anti-skin aging effects.
CN201910926272.7A 2019-09-27 2019-09-27 Preparation method of composition with anti-saccharification and anti-skin-aging functions Pending CN110664677A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111700831A (en) * 2020-07-02 2020-09-25 上海嘉亨日用化学品有限公司 Anti-aging skin care product composition with wrinkle removing effect, preparation method and application thereof
CN112043645A (en) * 2020-10-06 2020-12-08 青岛姿之妍化妆品科技有限责任公司 Skin care composition
CN113577001A (en) * 2021-09-10 2021-11-02 天津捷昂康生物科技发展有限公司 Fresh dendrobium antioxidant composition, preparation method and application of antioxidant
CN114392323A (en) * 2021-12-30 2022-04-26 上海家化联合股份有限公司 Anti-glycation traditional Chinese medicine extract
CN115025129A (en) * 2021-03-05 2022-09-09 葡萄王生技股份有限公司 Lactobacillus-containing composition and application thereof in preventing and/or improving skin aging

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111700831A (en) * 2020-07-02 2020-09-25 上海嘉亨日用化学品有限公司 Anti-aging skin care product composition with wrinkle removing effect, preparation method and application thereof
CN111700831B (en) * 2020-07-02 2022-07-19 上海嘉亨日用化学品有限公司 Anti-aging skin care product composition with wrinkle removing effect, preparation method and application thereof
CN112043645A (en) * 2020-10-06 2020-12-08 青岛姿之妍化妆品科技有限责任公司 Skin care composition
CN115025129A (en) * 2021-03-05 2022-09-09 葡萄王生技股份有限公司 Lactobacillus-containing composition and application thereof in preventing and/or improving skin aging
CN115025129B (en) * 2021-03-05 2024-04-19 葡萄王生技股份有限公司 Composition containing lactobacillus and use thereof for preventing and/or improving skin aging
CN113577001A (en) * 2021-09-10 2021-11-02 天津捷昂康生物科技发展有限公司 Fresh dendrobium antioxidant composition, preparation method and application of antioxidant
CN113577001B (en) * 2021-09-10 2024-04-19 天津捷昂康生物科技发展有限公司 Fresh dendrobium anti-oxidation composition, preparation method and application of anti-oxidation compound
CN114392323A (en) * 2021-12-30 2022-04-26 上海家化联合股份有限公司 Anti-glycation traditional Chinese medicine extract
WO2023124649A1 (en) * 2021-12-30 2023-07-06 上海家化联合股份有限公司 Anti-glycation traditional chinese medicine extract

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