CN104914263B - Blood cell analyzer strength cleaning solution automatic filling method and device - Google Patents

Blood cell analyzer strength cleaning solution automatic filling method and device Download PDF

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Publication number
CN104914263B
CN104914263B CN201510359361.XA CN201510359361A CN104914263B CN 104914263 B CN104914263 B CN 104914263B CN 201510359361 A CN201510359361 A CN 201510359361A CN 104914263 B CN104914263 B CN 104914263B
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cleaning solution
strength cleaning
road
automatic filling
strength
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CN104914263A (en
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谭玉华
秦军芳
张炎
梁铁柱
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Exxon Guangzhou Bio Tech Ltd
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Exxon Guangzhou Bio Tech Ltd
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Abstract

The present invention relates to blood of human body detection technique field.Blood cell analyzer strength cleaning solution automatic filling method and device, including driving sampling syringe to connect sampling needle by the road by motor, reaction tank is respectively by the road with the connection flow chamber outlet of two three-way electromagnetic valves and through pinch valve interface channel sample entrance port, counting chamber, sampling needle is fixed on sampling needle motion to be made vertically as well as horizontally, the balancing gate pit for being connected to positive pressure pump connects strength cleaning solution bottle input port with two three-way electromagnetic valves by the road, the delivery outlet of strength cleaning solution bottle is by the road with barrier film check valve coupled reaction pond and flow chamber outlet and through pinch valve interface channel sample entrance port.Strength cleaning solution automatic filling method is the step of the mat woven of fine bamboo strips one emptying pipeline and pond liquid, the step pressure injection of the mat woven of fine bamboo strips two and distribution strength cleaning solution, the immersion of the step of the mat woven of fine bamboo strips three.The present invention makes instrument maintenance more automate to be realized with a low cost strength cleaning solution automatic filling function, and shutdown process can be unattended, improves Consumer's Experience.

Description

Blood cell analyzer strength cleaning solution automatic filling method and device
Technical field
The present invention relates to blood of human body detection technique field, particularly a kind of blood cell analyzer strength cleaning solution is automatic Charging method and device.
Background technology
Blood cell analyzer belongs to medical precision instrument, is the relevant information for measuring blood cell, when using, its System easily has waste liquid impurity residual protein to accumulate causes the blocking of instrument system inside or measurement result inaccurate, so needing Want daily and periodically safeguarded.Typically safeguard it is indeterminable in the case of, it is necessary to system is carried out with strength cleaning solution Soaking and washing, strength cleaning solution are because its corrosivity is strong, expensive, and its consumption is fewer, improper long pipe runs conveying Avoid wasting, it can not be allowed directly to be flowed through from magnetic valve again, easily corrosion magnetic valve internals is contacted for a long time, can not The liquid bottle opening that strength cleaning solution will be filled is put into machine or takes from dynamic distribution covering to be added with sampling pin puncture, open or wear Thorn easily makes strength cleaning solution volatilization crystallization and corrosion instrument interior structure.So current be placed on outside machine using act bottle manually Repeatedly draw strength cleaning solution under sampling needle to realize soaking and washing function, the method needs artificial multi-pass operation, and instrument Generally also need to carry out once the operation of strength cleaning solution soaking and washing during daily shutdown, because the instrument whole shutdown process time compares It is long, if people's liquid feeding on duty again, it appears cumbersome and waste of manpower, cause Consumer's Experience bad.
The content of the invention
It is an object of the invention to provide a kind of letter of structure Zhuo, low cost, the blood cell that instrument maintenance is automated can be realized Analyzer strength cleaning solution automatic filling method and device.
The purpose of the present invention is achieved through the following channels:
Blood cell analyzer strength cleaning solution automatic filling device, including sampling syringe 14 is driven through pipe by motor 16 Road connects sampling needle 12, and DIFF reaction tanks 11 are respectively by the road with two three-way electromagnetic valve V2 connection flow chambers outlet 9 and through clamp Valve PV1 connection DIFF channel samples entrance 6, WBC counting chambers 17, RBC counting chambers 18, the sampling needle 12 is fixed on sampling needle fortune The balancing gate pit 2 for making vertically as well as horizontally to be connected to positive pressure pump 1 on motivation structure 13 connects strength cleaning with two three-way electromagnetic valve V1 by the road Liquid 4 input port A of bottle, the delivery outlet B of the strength cleaning solution bottle 4 connects the He of DIFF reaction tanks 11 with barrier film check valve 7 by the road Flow chamber exports 9 and through pinch valve PV1 connection DIFF channel samples entrance 6.
Further it is:It is that gas pressure sensor 3 is connected in the balancing gate pit 2.
Further it is:It is equipped with level sensing optocoupler 5 on the pipeline of the delivery outlet B of the strength cleaning solution bottle 4.
Blood cell analyzer strength cleaning solution automatic filling method is to use following steps:
The step of the mat woven of fine bamboo strips one empties pipeline and pond liquid, by DIFF reaction tanks, WBC counting chambers, RBC counting chambers and connecting line Waste liquid is emptied from waste liquid outlet;
The step pressure injection of the mat woven of fine bamboo strips two and distribution strength cleaning solution, after building malleation to balancing gate pit with positive pressure pump, pressure injection strength cleaning solution bottle Interior strength cleaning solution flows into DIFF reaction tanks, strong in sampling needle motion up-sampling pin suction DIFF reaction tanks with being fixed on Power cleaning solution stream, in distribution to WBC counting chambers, RBC counting chambers;
The step of the mat woven of fine bamboo strips three is soaked, and the desired amount of strength cleaning solution is all added in DIFF reaction tanks, WBC counting chambers, RBC counting chambers Afterwards, the strength cleaning solution in pond is diluted, the cleaning solution after dilution is then transported to the immersion of each position of analyzer.
The positive effect of the present invention:Blood cell analyzer strength cleaning solution automatic filling method and device of the present invention is utilized Part in existing five classification blood cell analyzer liquid-way system, DIFF is filled into using pressure-driven processes by strength cleaning solution Chi Zhong, then draws strength cleaning solution by sampling needle from DIFF ponds, is then redistributed in WBC, RBC counting chamber, so that Realize the function of five classification blood cell analyzer strength cleaning solution soaking and washing instruments.The present invention be realized with a low cost strength Cleaning solution automatic filling function, substitutes under the dynamic act bottle of current blood analyser armrest is placed on the outer sampling needle of machine and repeatedly draws strength clearly Clean liquid realizes soaking and washing function, instrument maintenance is more automated, and shutdown process can be unattended, improves Consumer's Experience.
Brief description of the drawings
Fig. 1 is structural representation of the invention
In figure:1. positive pressure pump, 2. balancing gate pit, 3. gas pressure sensor, 4. strength cleaning solution bottle, 5. level sensing light Coupling, 6.DIFF channel sample entrances, 7. barrier film check valve, 8. three-way connection, 9. flow chamber outlet, 10. three-way connection, 11.DIFF reaction tanks, 12. sampling needles, 13. sampling needle motions, 14. sampling syringes, 15. dilution entrances, 16. electricity Machine, 17.WBC counting chambers, 18.RBC counting chambers, the three-way electromagnetic valves of V1. two, the three-way electromagnetic valves of V2. two, PV1. pinch valves
Specific embodiment
The present invention is elaborated with reference to Figure of description:
Embodiment, as shown in figure 1, blood cell analyzer strength cleaning solution automatic filling device of the present invention includes:Malleation Pump 1, balancing gate pit 2, gas pressure sensor 3, strength cleaning solution bottle 4, level sensing optocoupler 5, flow chamber outlet 9, DIFF passages Sample entrance port 6, DIFF reaction tanks 11, sampling needle 12, sampling needle motion 13, sampling syringe 14, motor 16, WBC is counted Pond 17, RBC counting chambers 18, two three-way electromagnetic valve V1, two three-way electromagnetic valve V2, pinch valve PV1, barrier film check valve 7, three-way connection 8, three Pass joint 10.In blood cell analyzer strength cleaning solution automatic filling device, positive pressure pump 1, gas pressure sensor 3, two lead to Magnetic valve V1 is connected by pipeline with balancing gate pit 2 respectively.Positive pressure pump 1 is used for setting up pressure, and gas pressure sensor 3 is used for monitoring Pump builds the pressure value of pressure.Two three-way electromagnetic valve V1 are connected by pipeline with the bottle cap joint A of strength cleaning solution bottle 4.Strength cleaning solution bottle 4 Bottle cap joint B the one end of barrier film check valve 7 is connected to by pipeline, a level sensing on the close bottle cap end set of this section of pipeline This section of pipeline, is entered pinch valve PV1 normal-closed ends by optocoupler 5 near the side pressure of barrier film check valve 7.The other end of barrier film check valve 7 connection three Pass joint 8, the one end of three-way connection 8 connection flow chamber outlet 9, sets two three-way electromagnetic valve V2 in intermediate duct, three-way connection 8 is another End connection three-way connection 10.The one end of three-way connection 10 connects through the normally opened ends of pinch valve PV1 with DIFF channel samples entrance 6, threeway The other end of joint 10 is connected with DIFF reaction tanks 11.Sampling needle 12 is fixed on sampling needle motion 13, needle movement of sampling Mechanism 13 can be such that sampling needle 12 makees vertically as well as horizontally, and sampling needle 12 is connected by pipeline with sampling syringe 14, sampling note Emitter 14 is driven by motor 16, and dilution entrance 15 is provided with sampling syringe 14.Connection=gas in balancing gate pit 2 Pressure sensor 3, in the pressure value built in the pressure time in real-time monitoring system of regulation, when the pressure value in system reaches setting Target after, system will stop building pressure immediately, when build pressure the time period in pressure value be less than sets target value after, system meeting again It is immediately performed to build and presses work, if pressure value is consistently less than certain value of setting, illustrates to build and press unsuccessful, the system failure is reported at once Alert prompting.A level sensing optocoupler 5 is socketed on the pipeline of bottle cap end B on the drain pipe road of strength cleaning solution bottle 4, when in pipe When having liquid and no liquid, the voltage signal of optocoupler receiving terminal is different, and strength cleaning solution bottle is monitored using the principle Inside whether there is liquid, it's not true will point out user to change.Pinch valve PV1 and three is connected on strength cleaning solution export pipeline A barrier film check valve 7 is concatenated between first 8.When pinch valve PV1 can go up electricity when leukocyte differential count pushes away sheath stream, then strongly The normal-closed end that cleaning solution export pipeline is pressed into pinch valve PV1 will be opened, and such three-way connection 8 connects to strength cleaning solution bottle 4 Lead to, the waste liquids for having flow chamber outlet 9 to release pour in down a chimney the risk into strength cleaning solution bottle 4, and one barrier film check valve 7 of concatenation is just The problem can be solved.It is pressed into DIFF reaction tanks 11 in whole process in bottle 4 in strength cleaning solution, strength cleaning solution is obstructed Cross inside magnetic valve, in the absence of corrosion magnetic valve problem, and under not use state cleaning solution bottle two ends be all it is closed, also not There is a problem of volatile zone.
Blood cell analyzer strength cleaning solution automatic filling device, its charging method comprises the following steps:
The step of the mat woven of fine bamboo strips one empties pipeline and pond liquid, is counted DIFF reaction tanks 11, WBC using the original emptier of blood analyser Number pond 17, RBC counting chambers 18 are emptied from each waste liquid outlet.Emptying common pall be using the original device of blood analyser from Suction is until the pipe evacuation being connected with DIFF reaction tanks 11 and three-way connection 10 at DIFF channel samples entrance 6, it is therefore an objective to allow Strength cleaning solution is not diluted when flowing through this section of common pall by liquid in pipe.
The step pressure injection of the mat woven of fine bamboo strips two and distribution strength cleaning solution, open two three-way electromagnetic valve V1, while opening positive pressure pump 1 in the stipulated time It is interior to carrying out building malleation in balancing gate pit 2 and strength cleaning solution bottle 4, the monitoring pressure in real time value of gas pressure sensor 3 sets when reaching Stop building pressure after the pressure value that sets the goal.The size of target pressure value is according to strength cleaning solution bottle 4 to this section knot of DIFF reaction tanks 11 Depending on the flow resistance of structure and the liquid measure of needs filling.To the pressure injection strength cleaning solution of DIFF reaction tanks 11, build after pressing and open pinch valve PV1 so that strength cleaning liquid pipeline is communicated with DIFF reaction tanks 11, and strength cleaning solution is from bottle cap joint B under the driving of pressure Flow into DIFF reaction tanks 11.Electric opening time is according to positive pressure pressure size and depending on need to filling liquid measure on pinch valve PV1.Strength is clear The distribution of clean liquid, by strength cleaning solution pressure injection to DIFF reaction tanks 11 after, sampling needle motion 13 moves sampling needle level 12 Vertically move to the top of DIFF reaction tanks 11 and then again and make sampling needle stretch into DIFF reaction tanks 11 to drive injection by motor 16 Device 14 draws quantitative strength cleaning solution, then go up again level, move vertically to WBC counting chamber 17/RBC counting chambers 18 in will be strong In power cleaning solution injection pond.
The step of the mat woven of fine bamboo strips three is soaked, and the desired amount of strength cleaning solution is all added in DIFF reaction tanks, WBC counting chambers, RBC counting chambers Afterwards, the strength cleaning solution in pond is diluted with blood analyser original part, then conveys the cleaning solution after dilution To the immersion of each position of analyzer.
When the total consumption of strength cleaning solution needed for three ponds more than a pressure injection to liquid measure in DIFF reaction tanks when, can To repeat second step.

Claims (3)

1. a kind of blood cell analyzer strength cleaning solution automatic filling device, including sampling syringe is driven by motor (16) (14) connection sampling needle (12) by the road, DIFF reaction tanks (11) are exported with two three-way electromagnetic valve V2 connection flow chambers by the road respectively (9) DIFF channel samples entrance (6), WBC counting chambers (17), RBC counting chambers (18), its feature and through pinch valve PV1 are connected It is that the sampling needle (12) is fixed on sampling needle motion (13) and makees vertically as well as horizontally, to be connected to the pressure of positive pressure pump (1) Power room (2) meets strength cleaning solution bottle (4) input port A, the output of the strength cleaning solution bottle (4) with two three-way electromagnetic valve V1 by the road Mouth B connects DIFF reaction tanks (11) and flow chamber outlet (9) and is connected through pinch valve PV1 with barrier film check valve (7) by the road DIFF channel samples entrance (6).
2. blood cell analyzer strength cleaning solution automatic filling device according to claim 1, it is characterised in that the pressure Gas pressure sensor (3) is connected on power room (2).
3. blood cell analyzer strength cleaning solution automatic filling device according to claim 1, it is characterised in that described strong Level sensing optocoupler (5) is housed on the pipeline of power cleaning solution bottle (4) delivery outlet B.
CN201510359361.XA 2015-06-24 2015-06-24 Blood cell analyzer strength cleaning solution automatic filling method and device Active CN104914263B (en)

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CN110741257B (en) * 2017-06-30 2023-10-20 深圳迈瑞生物医疗电子股份有限公司 Sample analyzer and driving method thereof
CN109212246B (en) * 2017-06-30 2022-06-24 深圳迈瑞生物医疗电子股份有限公司 Liquid supply device, sample analyzer, pressure building device and liquid supply method

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CN101236149B (en) * 2007-02-02 2011-04-20 深圳迈瑞生物医疗电子股份有限公司 Stream type cell detection device and its accomplished stream type cell detection method
CN101246180B (en) * 2007-02-16 2012-11-21 深圳迈瑞生物医疗电子股份有限公司 Blood cell analyzer cleaning agent automatic filling method and device
JP5805136B2 (en) * 2013-05-16 2015-11-04 株式会社堀場製作所 Whole blood blood cell immunoassay device
CN104127192B (en) * 2013-10-16 2016-08-10 深圳市帝迈生物技术有限公司 A kind of flow cytometer fluid system and FCM analysis method
CN103994962B (en) * 2014-04-25 2016-08-24 深圳市帝迈生物技术有限公司 A kind of flow cytometer fluid system and FCM analysis method
CN205120724U (en) * 2015-06-24 2016-03-30 广州埃克森生物科技有限公司 Automatic device of maring of powerful cleaning solution of blood cell analysis appearance

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