CN104906415A - Traditional Chinese medicine combination for treating blood-heat injuring collateral type purpura - Google Patents
Traditional Chinese medicine combination for treating blood-heat injuring collateral type purpura Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine combination for treating blood-heat injuring collateral type purpura. The traditional Chinese medicine is composed of anoectochilus formosanus, radices lithospermi, cuscuta chinensis, radix paeoniae rubra, moutan bark, radix semiaquilegiae, lalang grass rhizome, cirsium japonicum DC, sophora flower, rheum officinale, radix isatidis, cyrtomium rhizome, agrimonia pilosa, carbonized hair, albizia flower, liquorice, cortex dictamni, coptis chinensis, carbonized sanguisorba roots, herba cirsii, fructus sophorae, rhizoma nelumbinis and radix paeoniae alba. The traditional Chinese medicine combination for treating blood-heat injuring collateral type purpura has the advantages of being fast in effect, low in cost, little in toxic and side effect, not prone to relapse and the like, and is worthy of clinical promotion.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind ofly be used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura.
Background technology
Purpura (purpura) is the general name of color change after skin and mucosal bleeding.Anaphylactoid purpura (allergic purpura) and thrombocytopenic purpura (thrombocytopenic purpura) is divided in doctor trained in Western medicine.Doctor trained in Western medicine is thought, anaphylactoid purpura is because body causes the permeability of blood capillary and fragility to increase to some allergin generation allergy, cause the hemorrhage and edema of subcutaneous tissue, mucosa and internal organs, anaphylactogen can be caused by many factors such as medicine, food, pollen, insect bites; Thrombocytopenic purpura is that petechia, ecchymosis or visceral hemorrhage appear in the skin mucosa caused due to thrombocytopenia.
Doctor trained in Western medicine thinks that primary disease is relevant with immunity, treats based on antihistamine drug, corticosteroid hormone, immunosuppressant and antibiotic, and to morbidity, anxious sudden and violent patient has good mitigation, and short term effect certainly.But can not be satisfactory for chronic recurrent exerbation patient curative effect.Especially hormone and antibiotic, uses in large quantities for a long time and has certain side effect.
The traditional Chinese medical science is included into " mass formed by blood stasis " category this disease.Be divided into according to " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect " (ZY/T001.1 ~ 001.9-94) primary disease that wind heat hinders network type, heat in blood hinders network type, type of hyperactivity of fire caused by deficiency of YIN, QI failing to control blood type four class.The clinical manifestation that heat in blood hinders network type purpura is: skin is shown in livid purple or light violet color dot shape or speckle suddenly, rises one after another.Fever of the body excessive thirst, flushingly fires, can with bleeding from the gum, epistaxis, even to have blood in stool, hematuria, menorrhagia.Deep red tongue, dry, rough and yellow fur, rapid pulse is strong.
Summary of the invention
The object of the present invention is to provide and be a kind ofly used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, there is instant effect, spend low, toxic and side effects is little, the not easily advantage such as recurrence.
Be used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, its principle active component consists of: La Liye, Radix Arnebiae (Radix Lithospermi), Semen Cuscutae, Radix Polygoni Ciliinerve, Cortex Moutan, Radix Semiaquilegiae, Rhizoma Imperatae, pig brother tartar, Flos Sophorae, Radix Et Rhizoma Rhei, Radix Isatidis, Rhizoma Osmundae, Herba Agrimoniae, Crinis Carbonisatus, Flos Albiziae, Radix Glycyrrhizae, Cortex Dictamni, Rhizoma Coptidis, charred Radix Sanguisorbae, Herba Cirsii, the Fructus Sophorae, Nodus Nelumbinis Rhizomatis, the Radix Paeoniae Alba.
Described, be used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, be made up of the crude drug of following parts by weight: La Liye 15-25, Radix Arnebiae (Radix Lithospermi) 20-30, Semen Cuscutae 20-30, Radix Polygoni Ciliinerve 12-18, Cortex Moutan 12-18, Radix Semiaquilegiae 10-15, Rhizoma Imperatae 10-15, pig brother tartar 10-15, Flos Sophorae 15-20, Radix Et Rhizoma Rhei 10-18, Radix Isatidis 10-15, Rhizoma Osmundae 10-15, Herba Agrimoniae 10-15, Crinis Carbonisatus 12-18, Flos Albiziae 10-18, Radix Glycyrrhizae 8-15, Cortex Dictamni 8-12, Rhizoma Coptidis 8-12, charred Radix Sanguisorbae 8-12, Herba Cirsii 8-12, Fructus Sophorae 8-12, Nodus Nelumbinis Rhizomatis 8-12, Radix Paeoniae Alba 8-12.
Preferably, be used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, be made up of the crude drug of following parts by weight: La Liye 20, Radix Arnebiae (Radix Lithospermi) 25, Semen Cuscutae 25, Radix Polygoni Ciliinerve 15, Cortex Moutan 15, Radix Semiaquilegiae 12, Rhizoma Imperatae 12, pig brother tartar 12, Flos Sophorae 18, Radix Et Rhizoma Rhei 15, Radix Isatidis 12, Rhizoma Osmundae 12, Herba Agrimoniae 12, Crinis Carbonisatus 15, Flos Albiziae 15, Radix Glycyrrhizae 10, Cortex Dictamni 10, Rhizoma Coptidis 10, charred Radix Sanguisorbae 10, Herba Cirsii 10, the Fructus Sophorae 10, Nodus Nelumbinis Rhizomatis 10, the Radix Paeoniae Alba 10.
The pharmacological property of each component of Chinese medicine composition of the present invention is as follows.
La Liye: nature and flavor are sweet, micro-puckery, cool.There is effect of dispelling wind, heat clearing away, removing heat from blood.The present invention selects the glad Amaranthus mangostanus L. of Euphorbiaceae to belong to the leaf of golden-rimmed Mulberry, raw use.
Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.GUIXIN, Liver Channel.Can removing heat from blood, invigorate blood circulation, removing toxic substances rash.Be usually used in that heat in blood poison is contained, macule purple black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Chang Zuowei hemorrhage, blood-cooling drugs, heat and toxic materials clearing away medicine.The present invention selects gromwell root.
Semen Cuscutae: taste is micro-pungent, flat, for yin nourishing dredging collateral is top grade.The effect that " Mingyi Bielu " calls it to be had " supporting flesh reinforcing YIN-essence, hard muscles and bones ".Motherland's medical science is thought, Semen Cuscutae acrid-sweet flavor, and property is put down, and enters liver, kidney two warp.There is the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antiabortive effect.Can be used for soreness of waist and knee joint, sexual impotence, premature ejaculation, seminal emission, the enuresis, the frequent micturition heeltap, tinnitus, dizziness dim eyesight, visual deterioration, threatened abortion, the inferior disease of band.The present invention selects the seed of dicotyledon scammonia section plant Semen Cuscutae, cleaning, drying, raw use.
Radix Polygoni Ciliinerve: cold nature, bitter in the mouth.Return Liver Channel.There is effect of clearing away heat and cooling blood, eliminating stasis to stop pain.The present invention selects the root of Ranunculaceae Radix Paeoniae subfamily Paeonia Radix Paeoniae, raw use.
Cortex Moutan: cold in nature, bitter in the mouth, cool, be slightly cold.GUIXIN, liver, kidney, lung meridian.There are clearing away heat and cooling blood, promoting blood circulation to remove blood stasis
effect.Cure mainly: the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.Chang Zuowei blood-cooling drugs, diuretic medicine, anti-dampness drug.The present invention selects the dry root bark of ranunculaceae peony, dries and is used as medicine.
Radix Semiaquilegiae: sweet in the mouth, micro-hardship, micro-pungent, cold in nature, mild toxicity.Return liver, spleen, urinary bladder channel.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of relieving stranguria by diuresis." medical center bun want the property of medicine " is recorded: " heresy of eliminating pathogen in the liver, gallbladder, kidney life fire mutually, separates all pyretic toxicity, metal and stone poison of drug.Determine children's's palpitation with fear, control haematemesis, epistaxis, be coated with burn pyretic toxicity.”。The present invention selects the tuber of ranunculaceae plant Radix Semiaquilegiae, decontamination, and wash quickly is clean, dry.
Rhizoma Imperatae: cold in nature, sweet in the mouth; GUIXIN, lung, stomach, urinary bladder channel; Property is delayed into blood, falls and has liter, having cooling blood for hemostasis, clearing away heat and promoting production of body fluid, effect of inducing diuresis for treating stranguria syndrome.Cure mainly heat in blood to spit blood, epistaxis is spat blood, hematuria, metrorrhagia, purpura, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, edema, jaundice.The present invention selects the rhizome of grass Herba Imperatae, cleans, dries.
Pig brother tartar: cool in nature, sweet-bitter flavor.There is the function of cooling blood for hemostasis, clots absorbing detumescence.
cure mainly:epistaxis, spitting of blood, haematemesis, hematuria, dysfunctional uterine hemorrhage, postpartum hemorrhage, hepatitis, nephritis, mastitis, traumatic injury; Traumatic hemorrhage and carbuncle furuncle etc. are controlled in external.The present invention selects pig brother tartar herb on the ground, dries, is used as medicine.
Flos Sophorae: bitter in the mouth, cold nature, returns liver, large intestine channel; Enter blood to hold back and fall, body slightly falls apart; There is cooling blood for hemostasis, effect of purging liver-fire; Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia, spit blood, epistaxis, liver-fire is had a headache, conjunctival congestion and swelling pain, sore throat, aphonia, ulcer sores.From the angle of doctor trained in Western medicine, Flos Sophorae is containing materials such as rutin (i.e. rutin, Rytub), Quercetin (Quercetin), tannin, sophoradiol (sophoradiol), vitamin A.Research report, rutin can improve the function of blood capillary, and keep the normal resistance of blood capillary, prevent because capillary fragility is excessive, too high hemorrhage, hypertension, the diabetes caused of permeability, can preventing of clothes is hemorrhage.The present invention selects Flos Sophorae.
Radix Et Rhizoma Rhei: cold in nature, bitter in the mouth.Return stomach, large intestine, liver, spleen channel.There are heat and toxic materials clearing away, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling, let out damp and hot effect clearly.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.Radix Et Rhizoma Rhei is selected in the present invention.
Radix Isatidis: bitter in the mouth, cold in nature.Enter liver, stomach warp.Can heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving.The present invention selects the dry root of cruciferae isatis, picks clean impurity, cleans, runs through, and section, dries.
Rhizoma Osmundae: nature and flavor: pungent, bitter, cold.Enter lung meridian.Can heat-clearing and toxic substances removing.Cure mainly: for seasonal pathogen sense, partial heat person, heating is heavy, aversion to cold light, have a headache, swallow red, pharyngeal swelling, xerostomia and thirsty, red tongue, white and thin fur, floating pulse person." Bencao Tujing " is recorded: only epistaxis." the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: toxic removing, and hemostasis, separates noxious water." Shaanxi Chinese herbal medicine " is recorded: heat-clearing and toxic substances removing, hemostasis parasite killing.Infectious disease such as prevention epidemic encephalitis type B, mumps etc.Treating hematochezia, hematuria, epistaxis, menorrhagia, ascariasis, pinworm disease.The present invention selects the rhizome of Dryopteridaceae plant Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak, cleans, stripping and slicing, dry.
Herba Agrimoniae: bitter, cool, acrid in the mouth, puckery, property is partially warm, enters lung, liver, spleen three warp, can clearing away heat and cooling blood hemostasis, can give birth to Kidney-Yin void.This grass hemostasis and blood, again can tonification astringing to arrest bleeding, and its performance is flat inclined, therefore cold, hotly hemorrhagely all can to apply, and having effect of invigorating the spleen and replenishing QI, is the agent of robustness astringing to arrest bleeding.Herba Agrimoniae is containing agrimonine, and it can make reduced clotting time, and platelet increases, and has cardiotonic concurrently.The present invention selects Herba Agrimoniae herb to clean, and dries, cutting, raw use.
Crinis Carbonisatus: bitter, tepor.There is effect of repercussive, hemostasis, diuresis.Cure mainly: the cards such as haematemesis, epistaxis, dysentery, stranguria with blood, woman uterine bleeding and dysuria.The present invention selects Crinis Carbonisatus, removing impurity, and aqueous alkali washes away grease, and clear water rinses, and dries, and boils in a covered pot over a slow fire and forges into charcoal, cool.
Flos Albiziae: nature and flavor are sweet, flat, have Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, the improving eyesight that clears away heart-fire effect.The present invention selects the flower of Celastrus orbiculatus Thunb. section Herba Albiziae to be used as medicine.
Radix Glycyrrhizae: sweet in the mouth is sweet, property is gentle, enters the heart, spleen, lung, stomach four warp.Raw with cooler, can eliminating fire and detoxication, relieving spasm to stop pain.Radix Glycyrrhizae is also good at being in harmonious proportion the property of medicine, separates the poison of hundred medicines.Radix Glycyrrhizae is used in the present invention.
Cortex Dictamni: nature and flavor are bitter, salty, cold.Return spleen, lung, small intestinal, stomach, urinary bladder channel.
There is effect of heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances.Cure mainly: the rubella caused by wind heat noxious dampness; Eczema; Scabies; Jaundice; Damp-heat arthralgia.The present invention selects the root bark of Rutaceae herbaceos perennial shaggy-fruited dittany and Dictamnus angustifolius, strips root bark, section, dry.Raw use.
Rhizoma Coptidis: nature and flavor are bitter, cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Can heat clearing and damp drying, eliminating fire and detoxication.Be usually used in damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The present invention selects the dry rhizome of ranunculaceae plant Rhizoma Coptidis, and removing impurity, runs through rear shave, to dry or the used time smashs to pieces.
Charred Radix Sanguisorbae: picric acid; Cold; Nontoxic.Return, lung, kidney, large intestine channel.Can cooling blood for hemostasis, heat-clearing and toxic substances removing.Cure mainly haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.The present invention selects the dry root of Radix Sanguisorbae, and section, heats with high heat, fry to surface coke black, inner sepia, and spray clear water is a little, and go out most Mars, and taking-up cools completely.
Herba Cirsii: sweet, bitter, cold.GUIXIN, Liver Channel.Can cooling blood for hemostasis, removing blood stasis to reduce swelling.For epistaxis, spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus.The present invention selects the herb of feverfew field thistle, and drying is used as medicine.
The Fructus Sophorae: cold; Bitter; Return liver, large intestine channel.Can clearing away heat-fire, cooling blood for hemostasis.Have blood in stool for intestinal heat, hemorrhoid swell hemorrhage, and liver-heat is had a headache, dizzy conjunctival congestion.The present invention selects the dry mature fruit of leguminous plant Chinese scholartree, and cleaning, drying are used as medicine.
Nodus Nelumbinis Rhizomatis: be Rhizoma Nelumbinis coupling part, property is flat, sweet-puckery flavor.Containing asparagine, tannin etc., there is higher medical value, medicinally can shorten the bleeding time, have the effect of hemostasis scattered silt, control hemoptysis, haematemesis, hematuria, have blood in stool, metrorrhagia etc.The present invention selects the loose rhizome of nymphaeaceae plant lotus.Removing fibrous root, dries, raw use.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, is slightly cold, and has the effects such as easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receipts antiperspirant.Be applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.There are antibacterial, antipyretic, antiinflammatory, increase coronary flow containing paeoniflorin, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose in the Radix Paeoniae Alba.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc., adopts Radix Paeoniae Alba in the present invention.
The traditional Chinese medical science is thought, the Basic disease cause pathogenesis that heat in blood hinders network type purpura is: hyperactivity of toxic heat, the absurd row of forcing blood, channels of burning, blood extravasation, therefore sees skin petechia ecchymosis, and color and luster is scarlet; Blood, with fire liter, above goes out key then epistaxis clearly; The impaired then bleeding from the gum of stomach network; Hematemesis, to have blood in stool; Pyretic toxicity bet bladder then hematuria; Heating, vexed, thirsty, constipation are dominance of heat in the interior, hot and suffocating the resembling of blood system.
Chinese medicine composition of the present invention is with " heat-clearing and toxic substances removing, cooling blood for hemostasis " for technical scheme, and wherein La Liye, Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood, Semen Cuscutae is invigorated blood circulation yin nourishing.Radix Polygoni Ciliinerve, Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, Radix Semiaquilegiae dispersing swelling and dissipating binds, Rhizoma Imperatae, pig brother tartar strengthen the power of cooling blood for hemostasis.Flos Sophorae purging liver-fire, Radix Et Rhizoma Rhei eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling; Radix Isatidis, Rhizoma Osmundae strengthen the power of heat-clearing and toxic substances removing antiviral.Herba Agrimoniae, Crinis Carbonisatus tonify deficiency stop blooding.Flos Albiziae is regulated the flow of vital energy, calm the nerves, active.The Radix Glycyrrhizae mediation property of medicine, separates the poison of hundred medicines.Fang Zhongyong Rhizoma Osmundae, Cortex Dictamni, Cortex Moutan clearing away lung-heat are descending to ignite, and effectively to treat because blood is with fire liter, above go out key and the epistaxis caused clearly; With Rhizoma Coptidis with clearing away stomach-heat with hemostasis, effectively to treat the bleeding from the gum caused because stomach network is impaired; With the hemostasis of charred Radix Sanguisorbae clearing away heat-damp and promoting diuresis, Flos Sophorae astringing to arrest bleeding, effectively to treat because pathogenic heat damage gastrointestinal venation and causing is had blood in stool; With Herba Cirsii, the Fructus Sophorae, Nodus Nelumbinis Rhizomatis with clearing away heat and promoting diuresis, cooling blood for hemostasis, effectively to treat the hematuria, metrorrhagia, the menorrhagia that cause because of pyretic toxicity bet bladder; With the Radix Paeoniae Alba, Radix Glycyrrhizae relieving spasm to stop pain.
All medicines share above, and each property of medicine cooperatively interacts, all linked with one another, play the merit of heat-clearing and toxic substances removing, cooling blood for hemostasis altogether.Jointly reach and cure the object that heat in blood hinders network type purpura.
Preparation, instructions of taking and consumption:
Get side of the present invention, pulverized 80-200 mesh sieve, soak 30-60 minute with 8-10 times of cold water.First pass intense fire is fried boiling, and changes slow fire and is fried boiling 30 minutes, leach filtrate.Second time, in medicinal residues, add 4-5 times of water, intense fire is fried boiling, and changes slow fire and is fried boiling 40 minutes, leach filtrate.Twice filtrate mixing, obtains Chinese medicine composition of the present invention.Morning and evening 30 minutes after meal decoction being taken warmly at twice, each 150ml.Period in a medicine diet raw meat is peppery.
Below, in conjunction with specific embodiments, preparation method of the present invention is specifically addressed.
Embodiment 1:
(1) La Liye 25 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Semen Cuscutae 30 grams, Radix Polygoni Ciliinerve 18 grams, Cortex Moutan 18 grams, Radix Semiaquilegiae 15 grams, Rhizoma Imperatae 15 grams, pig brother tartar 15 grams, 20 grams, Flos Sophorae, Radix Et Rhizoma Rhei 18 grams, Radix Isatidis 15 grams, Rhizoma Osmundae 15 grams, Herba Agrimoniae 15 grams, Crinis Carbonisatus 18 grams, Flos Albiziae 18 grams, 15 grams, Radix Glycyrrhizae, Cortex Dictamni 12 grams, Rhizoma Coptidis 12 grams, charred Radix Sanguisorbae 12 grams, Herba Cirsii 12 grams, the Fructus Sophorae 12 grams, Nodus Nelumbinis Rhizomatis 12 grams, the Radix Paeoniae Alba 12 grams is taken;
(2) Chinese medicine composition of above-mentioned weight is pulverized 120 mesh sieves, soak 60 minutes with 8 times of cold water.First pass intense fire is fried boiling, and changes slow fire and is fried boiling 30 minutes, leach filtrate.Second time, in medicinal residues, add 4 times of water, intense fire is fried boiling, and changes slow fire and is fried boiling 40 minutes, leach filtrate.Twice filtrate mixing, obtains Chinese medicine composition of the present invention.
Embodiment 2:
(1) La Liye 15 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Semen Cuscutae 20 grams, Radix Polygoni Ciliinerve 12 grams, Cortex Moutan 12 grams, Radix Semiaquilegiae 10 grams, Rhizoma Imperatae 10 grams, pig brother tartar 10 grams, 15 grams, Flos Sophorae, Radix Et Rhizoma Rhei 10 grams, Radix Isatidis 10 grams, Rhizoma Osmundae 10 grams, Herba Agrimoniae 10 grams, Crinis Carbonisatus 12 grams, Flos Albiziae 10 grams, 8 grams, Radix Glycyrrhizae, Cortex Dictamni 8 grams, Rhizoma Coptidis 8 grams, charred Radix Sanguisorbae 8 grams, Herba Cirsii 8 grams, the Fructus Sophorae 8 grams, Nodus Nelumbinis Rhizomatis 8 grams, the Radix Paeoniae Alba 8 grams is taken;
(2) Chinese medicine composition of above-mentioned weight is pulverized 80 mesh sieves, soak 45 minutes with 10 times of cold water.First pass intense fire is fried boiling, and changes slow fire and is fried boiling 30 minutes, leach filtrate.Second time, in medicinal residues, add 5 times of water, intense fire is fried boiling, and changes slow fire and is fried boiling 40 minutes, leach filtrate.Twice filtrate mixing, obtains Chinese medicine composition of the present invention.
Embodiment 3:
(1) La Liye 20 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Semen Cuscutae 25 grams, Radix Polygoni Ciliinerve 15 grams, Cortex Moutan 15 grams, Radix Semiaquilegiae 12 grams, Rhizoma Imperatae 12 grams, pig brother tartar 12 grams, 18 grams, Flos Sophorae, Radix Et Rhizoma Rhei 15 grams, Radix Isatidis 12 grams, Rhizoma Osmundae 12 grams, Herba Agrimoniae 12 grams, Crinis Carbonisatus 15 grams, Flos Albiziae 15 grams, 10 grams, Radix Glycyrrhizae, Cortex Dictamni 10 grams, Rhizoma Coptidis 10 grams, charred Radix Sanguisorbae 10 grams, Herba Cirsii 10 grams, the Fructus Sophorae 10 grams, Nodus Nelumbinis Rhizomatis 10 grams, the Radix Paeoniae Alba 10 grams is taken;
(2) Chinese medicine composition of above-mentioned weight is pulverized 100 mesh sieves, soak 50 minutes with 10 times of cold water.First pass intense fire is fried boiling, and changes slow fire and is fried boiling 30 minutes, leach filtrate.Second time, in medicinal residues, add 4 times of water, intense fire is fried boiling, and changes slow fire and is fried boiling 40 minutes, leach filtrate.Twice filtrate mixing, obtains Chinese medicine composition of the present invention.
Below by clinical experiment, curative effect of the present invention is verified.
Clinical data
1.1 case selections:
It is in August, 2011 Linyi City in June ,-2014 Tancheng County skin anti-station outpatient service purpura patient that 61 examples observe case, meets " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect " (ZY/T001.1 ~ 001.9-94) relevant heat in blood and hinders the diagnostic criteria of network type purpura.Wherein man 35 example, female 26 example, 5 ~ 35 years old age, 17 years old mean age; All with skin purpura for primary symptom, companion bleeding from the gum, epistaxis, have blood in stool, the disease such as hematuria, menorrhagia.
1.2 Therapeutic Method:
Give patient's Chinese medicine composition of the present invention, at twice morning and evening 30 minutes after meal decoction being taken warmly, each 150ml.Period in a medicine diet raw meat is peppery.Take 2 weeks continuously.
1.3 efficacy assessment standards:
Draft according to " People's Republic of China's traditional Chinese medicine industry standard---Chinese medical disease Standardization of diagnosis and curative effect " (ZY/T001.1 ~ 001.9-94):
Cure: purpura purple point and General Symptoms disappear, and lab index recovers normal;
Take a turn for the better: cyanosis of the skin speckle obviously reduces, and General Symptoms alleviates, and lab index is improved:
Do not heal: cyanosis of the skin speckle, General Symptoms and lab index are all unchanged:
Effective percentage is cure rate, improvement rate sum.
1.4 therapeutic outcome
61 routine patients cure 46 examples (75.41%), 12 examples that take a turn for the better (19.67%), and do not heal 3 examples (4.92%), and effective percentage is 95.08%.Over the course for the treatment of tracing observation is carried out for 61 routine patients, does not find obvious untoward reaction.
Model case:
Case 1: Zhang, female, 16 years old, student.In July, 2012 goes to a doctor.On inspection, two lower limb large area purpura.Platelet number of having a blood test again is normal.Not fading of purpura pressure.Red tongue, rapid pulse and strong, menorrhagia.Be diagnosed as anaphylactoid purpura, Syndrome Types of TCM is that heat in blood hinders network type.Take side of the present invention, a course for the treatment of recovers.Continue to take drug withdrawal after a course for the treatment of, follow up a case by regular visits to 2 years, do not recur.
Case 2: Cai so-and-so, man, 42 years old, workman.In April, 2012 goes to a doctor.Nearly one week because of gingival hemorrhage, hematuria, lower limb purpura. and enter the diagnosis and treatment of Tancheng County First People's Hospital, be diagnosed as anaphylactoid purpura.With penicillin and hormone therapy, curative effect is undesirable.According to inspection of the tongue time medical and pulse-taking in conjunction with characteristics of incidence, be decided to be heat in blood and hinder network type purpura.Give side of the present invention treatment, take medicine a course for the treatment of, the state of an illness is clearly better.Recover after continuing to take for two courses for the treatment of.Follow up a case by regular visits to 3 years, do not recur.
Case 3: king so-and-so, female, 25 years old, professional.In October, 2011 goes to a doctor.Check as widespread skin purpura, ecchymosis, epistaxis, menorrhagia, at outer court's application hormone, intravenous immunoglobulin and the treatment of multiple Chinese and western drugs, less effective.In conjunction with inspection of the tongue and pulse-taking, Syndrome Types of TCM is that heat in blood hinders network type purpura.Take side of the present invention, two courses for the treatment of recovered.Continue to take drug withdrawal after a course for the treatment of, follow up a case by regular visits to 2 years, do not recur.
Claims (3)
1. one kind is used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, it is characterized in that, its principle active component consists of: La Liye, Radix Arnebiae (Radix Lithospermi), Semen Cuscutae, Radix Polygoni Ciliinerve, Cortex Moutan, Radix Semiaquilegiae, Rhizoma Imperatae, pig brother tartar, Flos Sophorae, Radix Et Rhizoma Rhei, Radix Isatidis, Rhizoma Osmundae, Herba Agrimoniae, Crinis Carbonisatus, Flos Albiziae, Radix Glycyrrhizae, Cortex Dictamni, Rhizoma Coptidis, charred Radix Sanguisorbae, Herba Cirsii, the Fructus Sophorae, Nodus Nelumbinis Rhizomatis, the Radix Paeoniae Alba.
2. be according to claim 1ly a kind ofly used for the treatment of the Chinese medicine composition that heat in blood hinders network type purpura, it is characterized in that, it is made up of the crude drug of following parts by weight: La Liye 15-25, Radix Arnebiae (Radix Lithospermi) 20-30, Semen Cuscutae 20-30, Radix Polygoni Ciliinerve 12-18, Cortex Moutan 12-18, Radix Semiaquilegiae 10-15, Rhizoma Imperatae 10-15, pig brother tartar 10-15, Flos Sophorae 15-20, Radix Et Rhizoma Rhei 10-18, Radix Isatidis 10-15, Rhizoma Osmundae 10-15, Herba Agrimoniae 10-15, Crinis Carbonisatus 12-18, Flos Albiziae 10-18, Radix Glycyrrhizae 8-15, Cortex Dictamni 8-12, Rhizoma Coptidis 8-12, charred Radix Sanguisorbae 8-12, Herba Cirsii 8-12, Fructus Sophorae 8-12, Nodus Nelumbinis Rhizomatis 8-12, Radix Paeoniae Alba 8-12.
3. the Chinese medicine composition of network type purpura is hindered according to the treatment heat in blood described in claim 1, it is characterized in that, it is made up of the crude drug of following parts by weight: La Liye 20, Radix Arnebiae (Radix Lithospermi) 25, Semen Cuscutae 25, Radix Polygoni Ciliinerve 15, Cortex Moutan 15, Radix Semiaquilegiae 12, Rhizoma Imperatae 12, pig brother tartar 12, Flos Sophorae 18, Radix Et Rhizoma Rhei 15, Radix Isatidis 12, Rhizoma Osmundae 12, Herba Agrimoniae 12, Crinis Carbonisatus 15, Flos Albiziae 15, Radix Glycyrrhizae 10, Cortex Dictamni 10, Rhizoma Coptidis 10, charred Radix Sanguisorbae 10, Herba Cirsii 10, the Fructus Sophorae 10, Nodus Nelumbinis Rhizomatis 10, the Radix Paeoniae Alba 10.
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| CN101658643A (en) * | 2009-09-15 | 2010-03-03 | 刘锋 | Medicament for treating allergic purpura |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
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|---|---|---|---|---|
| US6123947A (en) * | 1998-03-27 | 2000-09-26 | Zhou; James H. | Herbal composition and treatment methods |
| CN101658643A (en) * | 2009-09-15 | 2010-03-03 | 刘锋 | Medicament for treating allergic purpura |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
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