CN104906269A - Oral liquid for treating gall-stone - Google Patents
Oral liquid for treating gall-stone Download PDFInfo
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- CN104906269A CN104906269A CN201510366152.8A CN201510366152A CN104906269A CN 104906269 A CN104906269 A CN 104906269A CN 201510366152 A CN201510366152 A CN 201510366152A CN 104906269 A CN104906269 A CN 104906269A
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Abstract
The invention belongs to the field of traditional Chinese medicines, in particular provides an oral liquid for treating gall-stone, and aims to achieve the purpose of treating gall-stone by clearing heat and secreting galas well as soothing the liver and circulating qi. To achieve the purpose, the oral liquid is prepared from the following raw materials as active components: 20 parts of drymoglossum piloselloides, 18 parts of japanese violet herb or root, 6 parts of radix bupleuri, 10 parts of bitter oranges, 12 parts of radix paeoniae alba, 25 parts of lysimachia christinae, 15 parts of dandelion, 15 parts of giant knot weed, 9 parts of chicken's gizzard-membranes, 12 parts of honeysuckle, 10 parts of scutellaria baicalensis, 12 parts of pyrrosia lingua, 10 parts of lygodium japonicum, 9 parts of rheum officinale and 3 parts of liquorice. A corresponding preparation method is also adopted. The oral liquid has the effect of treating gall-stone.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of be used for the treatment of cholelithiasis oral liquid and method for making and application.
Background technology
Cholelithiasis refers to the disease caused by calculus occurred in gallbladder, is a kind of commonly encountered diseases.Increase with the age, sickness rate also raises gradually, and women is obviously more than male.The origin cause of formation of cholelithiasis is very complicated, and some is not modifiable factor, such as: the age increased gradually, women, race, gene and family history; Some is acquired disposition, part can reverse, such as: gestation, obesity, low fiber, high calorie dietary structure, long-time fasting, therefore the medicine finding with Chinese herbal medicine the treatment cholelithiasis being primary raw material has caused the close attention of numerous scientific and technical personnel, and Chinese medicine cholelithiasis has also become a current important topic.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of be used for the treatment of cholelithiasis oral liquid and method for making and application.
Technical scheme: the object of the invention is by following scheme realize:
Be used for the treatment of an oral liquid for cholelithiasis, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Drymoglossum Herba Drymoglossi 20 parts, Herba Violae japonicae 18 parts, Radix Bupleuri 6 parts, Fructus Aurantii 10 parts, the Radix Paeoniae Alba 12 parts, Herba Lysimachiae 25 parts, Herba Taraxaci 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Endothelium Corneum Gigeriae Galli 9 parts, Flos Lonicerae 12 parts, Radix Scutellariae 10 parts, Folium Pyrrosiae 12 parts, Spora Lygodii 10 parts, Radix Et Rhizoma Rhei 9 parts, 3 parts, Radix Glycyrrhizae.
The described oral liquid being used for the treatment of cholelithiasis, preparation method comprises the steps: that getting above-mentioned medical material merges, and decocts with water twice, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10-1.20, adds ethanol and makes the percent by volume of alcohol content reach 65-85%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20-1.30 and reclaims ethanol, obtains extractum, add suitable amount of sucrose and water, make oral liquid.
The described oral liquid being used for the treatment of cholelithiasis, in preparation method, decocting condition is: first time adds water as the 8-12 times amount of medical material weight, decocts 1-2h, and second time adds water as the 6-10 times amount of medical material weight, decocts 1-2h.
The described oral liquid being used for the treatment of cholelithiasis, in preparation method, spray drying condition is: inlet temperature is 100-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
The application of oral liquid in preparation treatment cholelithiasis medicine of described treatment cholelithiasis.
Drymoglossum Herba Drymoglossi is that Polypodiaceae Drymoglossum Herba Drymoglossi belongs to small-sized Epiphyte, the antipyretic antiinflammatory of energy, wind dispelling cold expelling, clearing away lung-heat to relieve cough and hemostasis.Classification system is Drymoglossum piloselloides (L.) C.Presl, heat-clearing and toxic substances removing, hemostasia and detumescence.For jaundice, tuberculous lymphadenitis, parotitis, hemoptysis of pulmonary tuberculosis, metrorrhagia, breast carcinoma, traumatic injury.The present invention is with all herbal medicine.
Herba Violae japonicae derives from viola inconspicua Blume V.inconspicua Blume, with all herbal medicine.Gather herb when Xia Qiu is bloomed, dry.Meridian distribution of property and flavor: bitter, micro-pungent, cold.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For acute conjunctivitis, pharyngolaryngitis, acute icterohepatitis, mastitis, carbuncle furuncle and phyma poison, suppurative osteomyelitis, venom.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: from theory of Chinese medical science, Drymoglossum Herba Drymoglossi, Herba Violae japonicae, Radix Bupleuri, Fructus Aurantii, the Radix Paeoniae Alba, Herba Lysimachiae, Herba Taraxaci, Rhizoma Polygoni Cuspidati, Endothelium Corneum Gigeriae Galli, Flos Lonicerae, Radix Scutellariae, Folium Pyrrosiae, Spora Lygodii, Radix Et Rhizoma Rhei, Radix Glycyrrhizae clearing heat secreting bile in we, soothing the liver circulation of qi promoting, promoting blood circulation and stopping pain effect, is used for the treatment of cholelithiasis.Found by clinical application research, oral liquid of the present invention has well treatment cholelithiasis effect.Formulation of the present invention is reasonable, and compatibility is rigorous.The present invention consists of Chinese crude drug, has no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, embodiment 1: the preparation of oral liquid:
Get Drymoglossum Herba Drymoglossi 20g, Herba Violae japonicae 18g, Radix Bupleuri 6g, Fructus Aurantii 10g, Radix Paeoniae Alba 12g, Herba Lysimachiae 25g, Herba Taraxaci 15g, Rhizoma Polygoni Cuspidati 15g, Endothelium Corneum Gigeriae Galli 9g, Flos Lonicerae 12g, Radix Scutellariae 10g, Folium Pyrrosiae 12g, Spora Lygodii 10g, Radix Et Rhizoma Rhei 9g, Radix Glycyrrhizae 3g medical material also mixes, decoct with water twice, first time adds water as 12 times amount of medical material weight, decoct 2h, second time adds water as 10 times amount of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 DEG C), adding ethanol in proper amount makes alcohol content (volume fraction) reach 85%, stir, leave standstill 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 DEG C), obtain extractum, add suitable amount of sucrose and water, make oral liquid.
2. clinical data
2.1 Experimental agents: oral liquid of the present invention, by the preparation of above-described embodiment method, obtain oral liquid 5, specification: 10ml/ props up (being equivalent to containing crude drug 20g).
2.2 dosages: each 1, every day three times.The course for the treatment of: one month be a course for the treatment of, treated for 6 courses for the treatment of altogether.
2.3 are selected in 60 routine cholelithiasis patients altogether, all make a definite diagnosis with B ultrasonic.
2.4 the standard of curative effect evaluations: cure: calculus is got rid of completely, and pain all disappears, and sign is improved completely, happy, in high spirits.Effective: calculus is got rid of substantially, pain disappears, and sign is improved completely, happy, in high spirits.Effective: calculus part is got rid of, and pain disappears substantially, and sign makes moderate progress, mood and spirit are better.Invalid: calculus can not be got rid of, and pain still has, sign and symptom are improved not obvious or without improvement.
In the 2.5 60 routine cases of accepting for medical treatment, through treatment in 5 months, wherein cure 28 examples, effective 16 examples, effective 12 examples, invalid 4 examples, total effective rate reaches 93.3%.
Claims (5)
1. one kind is used for the treatment of the oral liquid of cholelithiasis, it is characterized in that, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Drymoglossum Herba Drymoglossi 20 parts, Herba Violae japonicae 18 parts, Radix Bupleuri 6 parts, Fructus Aurantii 10 parts, the Radix Paeoniae Alba 12 parts, Herba Lysimachiae 25 parts, Herba Taraxaci 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Endothelium Corneum Gigeriae Galli 9 parts, Flos Lonicerae 12 parts, Radix Scutellariae 10 parts, Folium Pyrrosiae 12 parts, Spora Lygodii 10 parts, Radix Et Rhizoma Rhei 9 parts, 3 parts, Radix Glycyrrhizae.
2. be used for the treatment of the oral liquid of cholelithiasis as claimed in claim 1, it is characterized in that preparation method comprises the steps: that getting above-mentioned medical material merges, and decocts with water twice, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10-1.20, adds ethanol and makes the percent by volume of alcohol content reach 65-85%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20-1.30 and reclaims ethanol, obtains extractum, add suitable amount of sucrose and water, make oral liquid.
3. be used for the treatment of the oral liquid of cholelithiasis according to claim 2, it is characterized in that, in preparation method, decocting condition is: first time adds water as the 8-12 times amount of medical material weight, decocts 1-2h, and second time adds water as the 6-10 times amount of medical material weight, decocts 1-2h.
4. be used for the treatment of the oral liquid of cholelithiasis according to claim 2, it is characterized in that, in preparation method, spray drying condition is: inlet temperature is 100-120 DEG C, leaving air temp is 80-90 DEG C, temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
5. treat the application of oral liquid in treatment cholelithiasis medicine of cholelithiasis as claimed in claim 1.
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CN201510366152.8A CN104906269A (en) | 2015-06-28 | 2015-06-28 | Oral liquid for treating gall-stone |
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CN201510366152.8A CN104906269A (en) | 2015-06-28 | 2015-06-28 | Oral liquid for treating gall-stone |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101274087A (en) * | 2008-05-14 | 2008-10-01 | 刘庆常 | Chinese medicine decoction for invigorating gallbladder and removing gall-stone |
CN104162097A (en) * | 2014-07-21 | 2014-11-26 | 温补来 | Traditional Chinese medicine preparation for treating cholelithiasis concurrent with fatty liver |
CN104173921A (en) * | 2014-08-04 | 2014-12-03 | 易爱玲 | Traditional Chinese medicine composition as well as preparation and application thereof |
-
2015
- 2015-06-28 CN CN201510366152.8A patent/CN104906269A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101274087A (en) * | 2008-05-14 | 2008-10-01 | 刘庆常 | Chinese medicine decoction for invigorating gallbladder and removing gall-stone |
CN104162097A (en) * | 2014-07-21 | 2014-11-26 | 温补来 | Traditional Chinese medicine preparation for treating cholelithiasis concurrent with fatty liver |
CN104173921A (en) * | 2014-08-04 | 2014-12-03 | 易爱玲 | Traditional Chinese medicine composition as well as preparation and application thereof |
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Application publication date: 20150916 |
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