CN104984312A - Traditional Chinese medicine composition for treating gallstones - Google Patents
Traditional Chinese medicine composition for treating gallstones Download PDFInfo
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- CN104984312A CN104984312A CN201510482892.8A CN201510482892A CN104984312A CN 104984312 A CN104984312 A CN 104984312A CN 201510482892 A CN201510482892 A CN 201510482892A CN 104984312 A CN104984312 A CN 104984312A
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Abstract
The invention belongs to the field of traditional Chinese medicine and provides a traditional Chinese medicine composition used for treating gallstones by clearing liver heat, promoting circulation of qi and promoting blood circulation to stop pain. In order to achieve the purpose, active ingredients contained in the traditional Chinese medicine composition comprise 20 parts of entadae stems, 18 parts of rubus lambertianus, 30 parts of semen plantaginis, 15 parts of radix scutellariae, 8 parts of inulae radix, 15 parts of euphorbia humifusae, 8 parts of orange peels, 10 parts of rhizoma pinelliae, 6 parts of coptidis rhizome, 4 parts of fructus amomi, 12 parts of radix paeoniae alba, 12 parts of hawthorns, 6 parts of dried ginger, 10 parts of atractylodes macrocephala koidz, 12 parts of saposhnicovia divaricata, 30 parts of gordon euryale seeds and 5 parts of radix glycyrrhizae. A corresponding preparation method is adopted. The traditional Chinese medicine composition has the effect of treating the gallstones.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of be used for the treatment of cholelithiasis Chinese medicine composition and method for making and application.
Background technology
Along with growth in the living standard, the change of dietary habit, the improvement of sanitary condition, the cholelithiasis of China changes into based on gallbladder cholesterol calculus for main gradually by with the bile pigment calculus of bile duct.The origin cause of formation of cholelithiasis is very complicated, and some is not modifiable factor, such as: the age increased gradually, women, race, gene and family history; Some is acquired disposition, and part can reverse, such as: gestation, obesity, low fiber, high calorie dietary structure, long-time fasting, cholelithiasis refers to the disease caused by calculus occurred in gallbladder, is a kind of commonly encountered diseases.Increase with the age, sickness rate also raises gradually, and women is obviously more than male.Therefore the medicine finding with Chinese herbal medicine the treatment cholelithiasis being primary raw material has caused the close attention of numerous scientific and technical personnel, and Chinese medicine cholelithiasis has also become a current important topic.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of be used for the treatment of cholelithiasis Chinese medicine composition and method for making and application.
Technical scheme: the object of the invention is by following scheme realize:
Be used for the treatment of a Chinese medicine composition for cholelithiasis, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Caulis Entadae 20 parts, Rubus lambertianus 18 parts, Semen Plantaginis 30 parts, Radix Scutellariae 15 parts, Radix Inulae 8 parts, 15 parts, the clothes made of brocade, Pericarpium Citri tangerinae 8 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Coptidis 6 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 12 parts, Fructus Crataegi 12 parts, Rhizoma Zingiberis 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 12 parts, Semen Euryales 30 parts, 5 parts, Radix Glycyrrhizae.
The described Chinese medicine composition being used for the treatment of cholelithiasis, preparation method comprises the steps: that getting above-mentioned medical material merges, and decocts with water twice, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10-1.20, adds ethanol and makes the percent by volume of alcohol content reach 65-85%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20-1.30 and reclaims ethanol, obtains extractum, add appropriate amount of auxiliary materials, make granule, tablet or capsule.
The described Chinese medicine composition being used for the treatment of cholelithiasis, in preparation method, decocting condition is: first time adds water as the 8-12 times amount of medical material weight, decocts 1-2h, and second time adds water as the 6-10 times amount of medical material weight, decocts 1-2h.
The described Chinese medicine composition being used for the treatment of cholelithiasis, in preparation method, spray drying condition is: inlet temperature is 100-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
The application of Chinese medicine composition in preparation treatment cholelithiasis medicine of described treatment cholelithiasis.
Rubus lambertianus is Rosaceae rubus lambert raspberry root, leaf is used as medicine.Autumn excavates, and root cleans section, by vegetable oil, equal amounts of wine and water fried dry.Leaf using fresh herb.Promoting blood flow to regulate menstruation, subduing swelling and detoxicating.For puerperal abdonimal pain, metrorrhagia, lochiopyra, dysmenorrhea, sciatica, rheumatic arthritis, hemiplegia; Wound hemorrhage is controlled in leaf external.The present invention is used as medicine with root.
Caulis Entadae is herb or the spore of lycopsid bar helictite, Latin plant name: Diphasiastrumcomplanatum (L.) Holub. [Lycopodium complanatum L., treatment summer-heat dysentery, Sunstroke generates heat; dysuria, acute toothache, infantile measles; External treatment sores ulceration of skin pyretic toxicity, erysipelas, flies infections skin ulcer, flies Serpentis ovum.The present invention is with all herbal medicine.All the other are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science is thought, cholelithiasis belongs to the category such as " hypochondriac pain ", " jaundice ", is because feelings will is smooth, and surfeit delicious food is greasy etc. causes depression of liver-QI, dysfunction of the spleen in transportation, damp and hot interior life, and heat decocts bile, condenses into stone; Stone resistance biliary tract, then raw all cards, therefore answer depressed liver-energy dispersing and function of gallbladder promoting, removing damp-heat, regulate the flow of vital energy and seek, pain relieving eliminating stagnation, in we, Caulis Entadae, Rubus lambertianus, Semen Plantaginis, Radix Scutellariae depressed liver-energy dispersing and function of gallbladder promoting, heat-clearing and toxic substances removing, soothing the liver dampness removing are monarch drug, Radix Inulae, the clothes made of brocade, Pericarpium Citri tangerinae, the Rhizoma Pinelliae, Rhizoma Coptidis, Fructus Amomi, the Radix Paeoniae Alba, Fructus Crataegi, Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Semen Euryales regulate the flow of vital energy and seek, blood circulation promoting and blood stasis dispelling, pain-relieving powder for treating become ministerial drug, Radix Glycyrrhizae is adjuvant, all medicines are harmonious, play heat-clearing and toxic substances removing, function of gallbladder promoting altogether, soothing the liver circulation of qi promoting, promoting blood circulation and stopping pain effect, is used for the treatment of cholelithiasis.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, embodiment 1 is prepared:
The preparation of granule: get Caulis Entadae 20 parts, Rubus lambertianus 18 parts, Semen Plantaginis 30 parts, Radix Scutellariae 15 parts, Radix Inulae 8 parts, 15 parts, the clothes made of brocade in ground, Pericarpium Citri tangerinae 8 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Coptidis 6 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 12 parts, Fructus Crataegi 12 parts, Rhizoma Zingiberis 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 12 parts, Semen Euryales 30 parts, Radix Glycyrrhizae 5 parts of medical materials also mix, decoct with water twice, first time adds water as 12 times amount of medical material weight, decoct 2h, second time adds water as 10 times amount of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 DEG C), adding ethanol in proper amount makes alcohol content (volume fraction) reach 85%, stir, leave standstill 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 DEG C), obtain extractum, add starch 50g, make granule.
The preparation of tablet: get Caulis Entadae 20 parts, Rubus lambertianus 18 parts, Semen Plantaginis 30 parts, Radix Scutellariae 15 parts, Radix Inulae 8 parts, 15 parts, the clothes made of brocade in ground, Pericarpium Citri tangerinae 8 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Coptidis 6 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 12 parts, Fructus Crataegi 12 parts, Rhizoma Zingiberis 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 12 parts, Semen Euryales 30 parts, Radix Glycyrrhizae 5 parts of medical materials also mix, decoct with water twice, first time adds water as 12 times amount of medical material weight, decoct 2h, second time adds water as 10 times amount of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 DEG C), adding ethanol in proper amount makes alcohol content (volume fraction) reach 85%, stir, leave standstill 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 DEG C), obtain extractum, add dextrin 50g, make tablet.
The preparation of capsule: get Caulis Entadae 20 parts, Rubus lambertianus 18 parts, Semen Plantaginis 30 parts, Radix Scutellariae 15 parts, Radix Inulae 8 parts, 15 parts, the clothes made of brocade in ground, Pericarpium Citri tangerinae 8 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Coptidis 6 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 12 parts, Fructus Crataegi 12 parts, Rhizoma Zingiberis 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 12 parts, Semen Euryales 30 parts, Radix Glycyrrhizae 5 parts of medical materials also mix, decoct with water twice, first time adds water as 12 times amount of medical material weight, decoct 2h, second time adds water as 10 times amount of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 DEG C), adding ethanol in proper amount makes alcohol content (volume fraction) reach 85%, stir, leave standstill 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 DEG C), obtain extractum, add dextrin 50g, make capsule.
2. clinical data
2.1 Experimental agents: granule of the present invention, by above-mentioned granule embodiment method preparation, obtain Chinese medicine granules 10 and wrap, specification: 10g/ wraps.
2.2 dosages: each 1 bag, every day three times.The course for the treatment of: one month be a course for the treatment of, treated for 6 courses for the treatment of altogether.
2.3 are selected in 60 routine cholelithiasis patients altogether, all make a definite diagnosis with B ultrasonic.
2.4 the standard of curative effect evaluations: cure: calculus is got rid of completely, and pain all disappears, and sign is improved completely, happy, in high spirits.Effective: calculus is got rid of substantially, pain disappears, and sign is improved completely, happy, in high spirits.Effective: calculus part is got rid of, and pain disappears substantially, and sign makes moderate progress, mood and spirit are better.Invalid: calculus can not be got rid of, and pain still has, sign and symptom are improved not obvious or without improvement.
In the 2.5 60 routine cases of accepting for medical treatment, through treatment in 6 months, wherein cure 31 examples, effective 18 examples, effective 7 examples, invalid 4 examples, total effective rate reaches 93.33%.
Model case: Chen, man, 47 years old, B ultrasonic was diagnosed as cholelithiasis, 2cm*1cm, took Chinese medicine granules of the present invention 6 months, and each 1 bag, every day three times, ultrasound diagnosis calculus is got rid of completely, and pain all disappears, and sign is improved completely, happy, in high spirits.
Claims (5)
1. one kind is used for the treatment of the Chinese medicine composition of cholelithiasis, it is characterized in that, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Caulis Entadae 20 parts, Rubus lambertianus 18 parts, Semen Plantaginis 30 parts, Radix Scutellariae 15 parts, Radix Inulae 8 parts, 15 parts, the clothes made of brocade, Pericarpium Citri tangerinae 8 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Coptidis 6 parts, Fructus Amomi 4 parts, the Radix Paeoniae Alba 12 parts, Fructus Crataegi 12 parts, Rhizoma Zingiberis 6 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Saposhnikoviae 12 parts, Semen Euryales 30 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the Chinese medicine composition of cholelithiasis as claimed in claim 1, it is characterized in that preparation method comprises the steps: that getting above-mentioned medical material merges, and decocts with water twice, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10-1.20, adds ethanol and makes the percent by volume of alcohol content reach 65-85%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.20-1.30 and reclaims ethanol, obtains extractum, add appropriate amount of auxiliary materials, make granule, tablet or capsule.
3. be used for the treatment of the Chinese medicine composition of cholelithiasis according to claim 2, it is characterized in that, in preparation method, decocting condition is: first time adds water as the 8-12 times amount of medical material weight, decocts 1-2h, second time adds water as the 6-10 times amount of medical material weight, decocts 1-2h.
4. be used for the treatment of the Chinese medicine composition of cholelithiasis according to claim 2, it is characterized in that, in preparation method, spray drying condition is: inlet temperature is 100-120 DEG C, leaving air temp is 80-90 DEG C, temperature of charge is 70-90 DEG C, atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
5. treat the application of Chinese medicine composition in treatment cholelithiasis medicine of cholelithiasis as claimed in claim 1.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105617280A (en) * | 2016-03-03 | 2016-06-01 | 冯字 | Traditional Chinese medicine composition for treating gallstone |
| CN105769984A (en) * | 2016-04-04 | 2016-07-20 | 孙爱华 | Extraction method of liquorice and antiviral medicine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100998843A (en) * | 2007-01-15 | 2007-07-18 | 曹国胜 | Medicinal composition for treating cholecystitis |
| CN102512630A (en) * | 2011-12-23 | 2012-06-27 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating gallbladder calculus |
| CN103800823A (en) * | 2014-01-26 | 2014-05-21 | 段寒 | Internal Chinese medicine composition for eliminating calculus and preparation method thereof |
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2015
- 2015-08-07 CN CN201510482892.8A patent/CN104984312A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100998843A (en) * | 2007-01-15 | 2007-07-18 | 曹国胜 | Medicinal composition for treating cholecystitis |
| CN102512630A (en) * | 2011-12-23 | 2012-06-27 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating gallbladder calculus |
| CN103800823A (en) * | 2014-01-26 | 2014-05-21 | 段寒 | Internal Chinese medicine composition for eliminating calculus and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 赵庆华: "刘学勤运用辛开苦降法验案举隅", 《新中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105617280A (en) * | 2016-03-03 | 2016-06-01 | 冯字 | Traditional Chinese medicine composition for treating gallstone |
| CN105769984A (en) * | 2016-04-04 | 2016-07-20 | 孙爱华 | Extraction method of liquorice and antiviral medicine |
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Application publication date: 20151021 |