CN1169557C - Chinese medicine for treating gout and process for preparing its instant particles - Google Patents

Abstract

The present invention relates to traditional Chinese medicine for treating gout, and a method for preparing a granule thereof, which belongs to the technical field of medicinal preparations. The formula of the traditional Chinese medicine comprises the following ingredients by weight ratio: 1 to 3 parts of saffron, 10 to 30 parts of clematis root, 10 to 30 parts of plantain herb, 10 to 20 parts of scrophularis, 10 to 20 parts of Japanese ampelopsis root, 10 to 20 parts of bittersweet herb, 3 to 8 parts of prepared dried ginger, 3 to 8 parts of epimedium and 10 to 20 parts of wolfberry bark. The preparation method of the granule comprises the following steps: firstly, mixing all the Chinese herbal medicine and decocting the Chinese herbal medicine in water so as to obtain juice; then, filtering the medicine juice, adding dextrin powder to the medicine juice and heating and concentrating a mixture of the medicine juice and the dextrin powder so as to obtain colloidal juice; next, drying the colloidal juice into grains so as to obtain the granule. The traditional Chinese medicine preparation has the advantages of appropriate compatibility, coordinate yin and yang and the treatment of both the manifestation and the root cause of a disease. The traditional Chinese medicine preparation can effectively promote the excretion of uric acid in human bodies and can inhibit the generation of uric acid. Meanwhile, the traditional Chinese medicine preparation also has various beneficial auxiliary functions of blood sugar reduction, blood fat reduction and cholesterol reduction. The granule has the advantages of convenience for taking, good mouth feel and easy absorption by human bodies.

Description

Chinese medicine of treatment goat and preparation method thereof

Technical field

The invention belongs to the medicinal preparation technical field, particularly relating to what treat goat is the Chinese medicine of raw material with the plant.

Background technology

According to modern medical theory, gout is that human body causes that to purine metabolic disturbance uric acid is too high in the blood, and in the joint, soft tissue, kidney etc. locate to form uratosis crystallization, calculus, and cause the pathological changes at these positions.The Western medicine of treatment goat mainly contains allopurinol at present, colchicine, and narcaricin, probenecid etc., they can be accelerated urate excretion to a certain extent and suppress uricopoiesis, but take for a long time, and bigger toxic and side effects is arranged.Chinese patent notification number CN1057700C discloses a kind of Chinese medicine of the treatment goat of being made up of Caulis Akebiae, Herba Leonuri, Semen Plantaginis, Semen Coicis, Rhizoma Atractylodis, Cortex Phellodendri and Radix Achyranthis Bidentatae.Chinese patent notification number CN1070070C also discloses a kind of Chinese medicine preparation of the treatment goat of being made up of Zaocys (processed with wine), Pheretima (parched), Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Caulis Trachelospermi, Herba Lycopodii, Radix et Cortex ulmi pumilae, Cortex Acanthopancis, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Caulis Akebiae, Cortex Phellodendri, Rhizoma Atractylodis, Radix Achyranthis Bidentatae etc. 21 flavor Chinese herbal medicine.Above-mentioned two kinds of Chinese medicines all are to execute according to differential diagnosis in tcm to administer the opinion prescription, have curative effect preferably, and do not have obvious toxic and side effects.

Summary of the invention

The Chinese medicine that the purpose of this invention is to provide another kind for the treatment of both the principal and secondary aspects of a disease, evident in efficacy, the treatment goat of taking safe ready.

The present invention specifically is that the Chinese herbal medicine by following weight proportion is the medicinal preparation for oral administration that raw material is made: Stigma Croci 1-3 part, Radix Clematidis 10-30 part, Herba Plantaginis 10-30 part, Radix Scrophulariae 10-20 part, Radix Ampelopsis 10-20 part, Herba Solani Lyrati 10-20 part, Rhizoma Zingiberis Preparatum 3-8 part, Herba Epimedii 3-8 part, Cortex Lycii 10-20 part.

Above-mentioned prescription compatibility principle: according to theory of Chinese medical science, gout should belong to damp and hot spleen disease, and pathogenic fire reducing is diffusing evil so prescription with clearing away heat with drugs sweet in flavor and cold in nature, is worked hard, and flat dampness removing is a purport.Wherein Stigma Croci is sweet flat, blood circulation promoting and blood stasis dispelling, and dispersing stagnation and relieving accumulation of pathogens is joined sweet cold Cortex Lycii, plays heat clearing and blood circulation promoting, the effect of anti-fiery blood sugar lowering; The Radix Clematidis antipyretic-antalgic, diuresis and dissolving urate are joined sweet cold Herba Plantaginis and are strengthened diuresis dampness removing the turbid descending heat clearing away effect, can increase the drainage of uric acid; Herba Solani Lyrati is sweet cold, heat-clearing and toxic substances removing, and inducing diuresis to remove edema is joined the cold Radix Ampelopsis of toil, strengthens the reducing swelling and alleviating pain effect, and two flavors cooperate can regulate immunity, promotes metabolism, gets rid of uric acid and resisting oxidation free radical effect; Radix Scrophulariae sweetness and bitterness is cold, eliminating fire and detoxication, and YIN nourishing and the production of body fluid promoting, the antiinflammatory antithrombotic, and the blood pressure lowering hypoglycemic activity is arranged; The hot temperature of Herba Epimedii, hot can loosing, but temperature the kidney invigorating are that the kidney invigorating dispelling the wind and dampness pathogens wins medicine.The scalable endocrine promotes metabolism, joins hot Rhizoma Zingiberis Preparatum, the promoting the circulation of blood arteries and veins, and wind-damp dispelling power is stronger.Above-mentioned side's invasion by pathogenic cold medicine is on the high side, is in fear of to hinder stomach, and assistant cooperates the Herba Epimedii warm nature again with Rhizoma Zingiberis Preparatum cold removing strengthening the spleen and stomach, and excessive cold invading middle-JIAO(the spleen and stomach) has temperature, and taste are ruled together, and negative and positive are coordinated, and QI and blood is in harmonious proportion.Thereby obtain to the goat treating both the principal and secondary aspects of a disease the also auxilliary simultaneously significant curative effect that multidirectional beneficial effects such as blood fat reducing, blood sugar lowering, cholesterol reducing are arranged, and the side effect that does not produce other infringement property.

Above-mentioned Chinese medicine can be made into pill, capsule, and medicinal preparation for oral administration such as powder are particularly made good absorbing effect.Mouthfeel is good, the electuary of taking convenience.

Its preparation method is:

(1) takes by weighing selected each component herbal decoction piece by proportioning;

(2) with the mixed decocting juice that adds of each herbal decoction piece;

(3) filter out medicine juice, add the dextrine powder heating and be condensed into glue juice;

(4) glue juice becomes granule with drier;

(5) sterilization, packing.

The specific embodiment

Embodiment 1, and I type powder for curing gout prescription is: 1 part of Stigma Croci, 10 parts of Radix Clematidis, 20 parts of Herba Plantaginiss, 20 parts of Radix Scrophulariaes, 10 parts of Radix Ampelopsis, 10 parts of Herba Solani Lyratis, 3 parts of Rhizoma Zingiberis Preparatums, 3 parts of Herba Epimedii, 10 parts of Cortex Lycii by weight.

Concrete method for making: (1) takes by weighing the each component herbal decoction piece by said ratio; (2) with the mixed decocting juice that adds of each herbal decoction piece; (3) filter out medicine juice, add the dextrine powder heating and be condensed into glue juice; (4) glue juice becomes granule with drier; (5) weighing and bagging, every bag 15 gram; (6) sterilization, the check warehouse-in.

This type prescription lighter early stage patient of the state of an illness that suits.

Embodiment 2, and II type powder for curing gout prescription is: 2 parts of Stigma Crocis, 20 parts of Radix Clematidis, 20 parts of Herba Plantaginiss, 15 parts of Radix Scrophulariaes, 15 parts of Radix Ampelopsis, 15 parts of Herba Solani Lyratis, 5 parts of Rhizoma Zingiberis Preparatums, 5 parts of Herba Epimedii, 15 parts of Cortex Lycii by weight.

The prescription of this proportioning adapts to more than the gout state of an illness 3-5, and symptom is heavier, and frequent patient shows effect.

Preparation method is with embodiment 1.

Embodiment 3, and III type powder for curing gout prescription is: 3 parts of Stigma Crocis, 30 parts of Radix Clematidis, 30 parts of Herba Plantaginiss, 20 parts of Radix Scrophulariaes, 20 parts of Radix Ampelopsis, 20 parts of Herba Solani Lyratis, 8 parts of Rhizoma Zingiberis Preparatums, 8 parts of Herba Epimedii, 20 parts of Cortex Lycii by weight.

The patient of the suitable middle and advanced stage of this proportioning prescription, and multiple symptom such as urate calculus is arranged.

Preparation method is with embodiment 1.

Clinical case 1, Min * *, the woman, 56 years old, Shanghai * * artist, suffered from gout 3 years, the sudden swollen burning pain of two foots, it is stiff to lie in bed, and seeks medical advice in domestic and international multidigit expert, alleviates when controlling, and can show effect again in a few days, repeatedly pain.On March 5th, 1998, come my clinic outpatient service, obey II type powder for curing gout of the present invention, every day each 1 time sooner or later, each 1 bag (15 gram), after the course of treatment (30 days), transference cure, blood uric acid is reduced to 360Umol/L from 520Umol/L.Continue 1 course of treatment, to consolidate, not recurrence again in 4 years so far.

Clinical case 2, Shen * *, man 54 years old, the Zhejiang Huzhou City * * cadre, suffered from gout more than 10 year, the two podocytic processes burning pain of swelling is taken western medicine, alleviates when taking medicine, but outbreak repeatedly.Examination clothes III type powder for curing gout of the present invention was cured after 2 courses of treatment, not recurrence in 5 years so far.Take the preceding blood test uric acid 560Umol/L of this electuary, blood glucose 6.8mmol/L, triglyceride 3.5mmol/L, cholesterol 5.5mmol/L, take this electuary after, through chemical examination for blood uric acid 390Umol/L, cholesterol 4.5mmol/L, glyceride 1.50mmol/L, blood glucose 5.1mmol/L.

Clinical case 3, Yu * *, man 49 years old, the Zhejiang Huzhou City soil pipe cadre of office, gout was taken I type powder for curing gout of the present invention and is promptly healed 2 courses of treatment 1 year more, not recurrence in 7 years so far.

Clinical case 4, slowly * *, the man, 56 years old, the soil pipe cadre of office of Zhejiang Province suffered from gout more than 10 year, and it is invalid to seek medical advice in many ways, and outbreak is repeatedly taken III type powder for curing gout of the present invention and is cured 3 courses of treatment, not recurrence in 5 years so far.

Use powder for curing gout treatment acute and chronic gout of the present invention clinical trial totally 3000 many cases, total effective rate reaches 95%, and wherein obvious effective rate reaches 60-70%, and kidney blemisher weak effect.

Claims (2)

1, a kind of Chinese medicine for the treatment of goat, it is characterized in that it is that Chinese herbal medicine by following weight proportion is the medicinal preparation for oral administration that raw material is made: Stigma Croci 1-3 part, Radix Clematidis 10-30 part, Herba Plantaginis 10-30 part, Radix Scrophulariae 10-20 part, Radix Ampelopsis 10-20 part, Herba Solani Lyrati 10-20 part, Rhizoma Zingiberis Preparatum 3-8 part, Herba Epimedii 3-8 part, Cortex Lycii 10-20 part.

2, a kind of preparation method of Chinese medicine of treatment goat as claimed in claim 1 is characterized in that:

(1) takes by weighing selected each component herbal decoction piece by proportioning;

(2) with the mixed decocting juice that adds of each herbal decoction piece;

(3) filter out medicine juice, add the dextrine powder heating and be condensed into glue juice;

(4) glue juice is dried to granule;

(5) sterilization, packing.