CN105381020A - Topical drug for treating rheumatoid bone pain - Google Patents
Topical drug for treating rheumatoid bone pain Download PDFInfo
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Abstract
The invention relates to a topical drug for treating rheumatoid bone pain. The topical drug is prepared from the following raw materials in parts by weight: Berchemia floribunda (Wall.) Brongn., Rubus blinii Levl., root and stem of kadsura oblongifolia, fructus cinnamoii, rubus reflexus, root and leaf of rubus alceaefolius poir, herba cladostachvdis, root and stem of ventilago leiocarpa benth, root, stem and fruit of akebia trifoliate, parasitic asiatic toddalia root, valeriana jatamansi, twig and leaf of common claoxylon, and illigera parviflora dunn. The invention also provides a preparation method of the topical drug. The topical drug provided by the invention has definite therapeutic effects, good safety and no side effects in respect of treating all kinds of rheumatoid bone pain caused by wind-cold-dampness meridian impotency, the use is convenient, the cost is low, and the effect is superior to the effect in the prior art.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of external used medicine for the treatment of rheumatic ostalgia.
Background technology
We daily said " rheumatism ", in the diagnosis of traditional medicine, be included into the diagnosis category of " arthromyodynia ".Arthromyodynia is due to exopathogen invasion and attack human bodies such as wind, cold, wets, impatency meridians, QI-blood circulation is smooth, causes the pain of limbs muscle BJM, weighs, miserable, numb, or the disease that joint joint stuffiness, stiff, enlargement, distortion etc. to show for cardinal symptom.Chinese medicine is thought, arthralgia due to wind-cold-dampness disease with liver deficiency of spleen and stomach be its sick this, the wind and cold damp-phlegm stasis of blood be its sick mark, unfavorable through BI-syndrome involved the blood vessels resistance, qi and blood stagnation is obstructed be its pathology, pathological changes mechanism can be summarized as " void, heresy, the stasis of blood " three.
" kidney governing bones, liver governing tendons ".Muscles and bones joint all relies Liver and kidney essence and blood to moisten foster.Muscle damage liver, bone injury kidney, lesions of liver and kidney then muscles and bones mistake is supported, and muscle does not fill.
" the spleen being the foundation of acquired constitution, main QI and blood is biochemical ".The body of old artificial many void, Deficiency and coldness of spleen and stomach, insufficiency of kidney-YANG are the most common; Deficiency of YANG QI, can not warm fortune blood in interior, internal organs of supplementing nutrition; Yang deficiency, in outward, can not defend outer imperial heresy, therefore easily ill, and often touching difficulty heals.So Liver and kidney spleen deficiency of qi and blood is the main intrinsic factor of primary disease.
" heresy that affection of exogenous wind-cold is damp and hot ", to the invasion and attack repeatedly of human body, stasis blocking meridians, QI and blood, form the stiff swelling of joint, deformity, with the passing of time difficult multiple.In a word, because primary disease is obstinate, the course of disease is permanent, must based on nourishing the liver and kidney, invigorating qi and benefiting blood, harmonizing the spleen and stomach in treatment, helps the principle for the treatment of of numbness analgesic therapy of reducing phlegm with dispeiling pathogenic wind and removing dampness, blood circulation promoting and blood stasis dispelling, dredging collateral, declare, can obtain good curative effect.
Summary of the invention
The object of this invention is to provide a kind of external used medicine for the treatment of rheumatic ostalgia.
The object of the invention is by following technical scheme realize:
The external used medicine for the treatment of rheumatic ostalgia of the present invention is prepared from by the raw material of Chinese medicine of following weight portion:
Yellow GUFENG 10-30 part, Herba Rubi blinii 3-10 part, little red brills 10-30 part, Fructus cinnamomi camphorae 10-30 part, Radix Rubi reflexi 10-30 part, lack elegant tight 3-10 part, nine layers of wind 5-20 part, purple nine Ns of 5-20 parts, blue nine Ns of 10-30 parts, Radix Toddaliae Asiaticae parasitism 3-10 part, Rhizoma valerianae latifoliae 3-10 part, yellow nine Ns of 10-20 parts, black nine Ns of 10-20 parts.
Preferably, be prepared from by the raw material of Chinese medicine of following weight portion:
Yellow GUFENG 15-25 part, Herba Rubi blinii 5-8 part, little red brills 15-25 part, Fructus cinnamomi camphorae 15-25 part, Radix Rubi reflexi 15-25 part, lack elegant tight 5-8 part, nine layers of wind 10-15 part, purple nine Ns of 10-15 parts, blue nine Ns of 15-25 parts, Radix Toddaliae Asiaticae parasitism 5-8 part, Rhizoma valerianae latifoliae 5-8 part, yellow nine Ns of 12-18 parts, black nine Ns of 12-18 parts.
Below the crude drug source of Chinese medicine preparation of the present invention:
Yellow GUFENG, Rhamnaceae plant spends more the Herb of Radix Berchemiae Giraldianae Berchemiafloribunda (Wall.) Brongn.Taste is micro-puckery, and property is put down.Dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral, regulating menstruation, pain relieving, relieving cough and resolving phlegm, liver heat removing and eyesight improving.
Herba Rubi blinii, the root of moraceae plants ficus simplicissima FicussimplicissimaLour..Sweet in the mouth, slightly warm in nature.Invigorating the spleen for eliminating dampness, promoting the circulation of QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral, preventing phlegm from forming and stopping coughing, tonifying the lung lactogenesis.
Little red brill, the root of Schisandraceae Plant cold meal rattan KadsuraoblongifoliaMerr., tendril.Sweet in the mouth, warm in nature.Expelling wind and removing dampness, promoting the circulation of QI to relieve pain.
Fructus cinnamomi camphorae is the dry mature fruit of Lauraceae cinnamon Cinnamomum Migao H.W.Li. (CinnamomummigaoH.W.Li).Xin Wen is nontoxic.Expelling cold and dampness, promoting the circulation of QI to relieve pain.Control vomiting and diarrhoea, cold syndrome of the stomach stomachache, beriberi, toxic swelling.
Radix Rubi reflexi, Rosaceae Radix Rubi reflexi RubusreflexusKer.var.lanceolataMetc., is used as medicine with root.Bitter, puckery, sour, flat.Wind-damp dispelling, bone and muscle strengthening.Cure mainly Fengshi Guanjie pain, quadriplegia is paralysed.
Lack elegant tight, root, the leaf of rosaceous plant Radix seu Folium Rubi alceaefolii RubusalceaefoliusPoir..Sweet in the mouth, light, property is put down.Blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood, inducing diuresis to remove edema, eliminating stasis to stop pain.
Nine layers of wind, the rattan of Papilionaceae plant spatholobus suberectus SPatholobussuberectusDunn.Sweet in the mouth, hardship, warm in nature.Blood circulation promoting and enriching, dredge the meridian passage, expelling wind and removing dampness.
Purple nine Ns, root, the stem of Rhamnaceae plant ventilago leiocarpa VentilagoleiocarpaBenth..Bitter in the mouth, warm in nature.Nourishing blood to expel wind, relaxing muscles and tendons and activating QI and blood in the collateral, benefit of reinforcing the kidney essence.
Lan Jiuniu, plants of Lardizabalaceae plain boiled water leads to root, stem, the fruit of Akebiatrifoliata (Thunb) Koidz.var.australis (Diels) Rehd..Bitter in the mouth, cool in nature.Fruit, promoting flow of QI and blood, promoting the production of body fluid to quench thirst, clearing away heat and promoting diuresis.Stem, mind calming relieving restlessness, promoting the production of body fluid to quench thirst, brings down a fever, dredge the meridian passage.Root, dispels the wind, diuresis, and promoting the circulation of QI to relieve pain are invigorated blood circulation.
Radix Toddaliae Asiaticae is parasitic, is the band stem branch and leaf of Loranthaceae Loranthus plant Herba Taxilli Loranthusparasiticus (L.) Merr., is used as medicine with Herb.Pungent, micro-hardship, temperature.Enter liver, stomach, kidney channel.Blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, dredge the meridian passage.Dispelling the wind and dampness pathogens arthralgia pain, epigastric distending pain, dysmenorrhea, amenorrhea, traumatic injury, hepatosplenomegaly, distending pain over the hypochondrium, chronic hepatitis, liver cirrhosis, liver swell and ache, venom.
Rhizoma valerianae latifoliae, Valerianaceae valerian Aranea grass ValerianajatamansiJones., is used as medicine with root stock and root.Pungent, micro-hardship, temperature.Promoting digestion and invigorating the stomach, regulating QI to relieve pain, removing toxic substances of dispeling the wind.Stomachache abdominal distention, dyspepsia, infantile malnutrition, gastroenteritis, dysentery, rheumatalgia, soreness of the waist and knees.
Huang Jiuniu, root, the stem of milk wort Radix securidacae SecuridacainappendiculataHassk..Acrid in the mouth, hardship, cold nature.Heat-clearing and toxic substances removing, diuresis, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.
Black nine Ns, root, rattan, the leaf of cohosh Radix Clematidis ClematischinensisOsbeck.Root, acrid in the mouth, micro-hardship, warm in nature.Leaf, bitter in the mouth, property is put down.Root, expelling wind and removing dampness, dredge the meridian passage, pain relieving, inducing diuresis to remove edema.Leaf, heat-clearing and toxic substances removing.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and the method adopts the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.Concrete preparation method is as follows:
Scheme one: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
Scheme two: get whole medical material, uses 40-80% alcohol reflux 2-3 time after mixing, and each ethanol consumption is 4-10 times of medical material total amount, extraction time is 1-4 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
Scheme three: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, and when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, add ethanol, make alcohol content be 40-70%, leave standstill 12-24 hour, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the extractum of 1.10-1.25, obtains active component.
The external used medicine for the treatment of rheumatic ostalgia of the present invention, is prepared from by the following method: get whole medical material, micronizing, and cross 300-400 mesh sieve, mix homogeneously, adds the flour of 1-2 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
The external used medicine for the treatment of rheumatic ostalgia of the present invention, be prepared from by the following method: get one of scheme one to scheme three gained active component, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, put into Mould Machining molding, to obtain final product.
During use, dough is heated to 40-50 DEG C, fomentation affected part.
Formula of the present invention is rationally innovated, yellow GUFENG, Herba Rubi blinii soothing the channels and quicking the network vessels in side, dampness removing pain relieving; Little red brill, Fructus cinnamomi camphorae expelling wind and cold, promoting the circulation of QI to relieve pain; Radix Rubi reflexi wind-damp dispelling, bone and muscle strengthening; Lack elegant tight blood circulation promoting and blood stasis dispelling, cooling blood and relieving pain; Nine layers of wind dredge the meridian passage, expelling wind and removing dampness; Purple nine Ns of nourishing blood to expel winds, relaxing muscles and tendons and activating QI and blood in the collateral; Blue nine Ns of promoting flow of QI and blood pain relievings; The parasitic blood circulation promoting and blood stasis dispelling of Radix Toddaliae Asiaticae, reducing swelling and alleviating pain, dredge the meridian passage; Rhizoma valerianae latifoliae regulating QI to relieve pain, dispels the wind; Yellow nine Ns of promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain; Black nine Ns of expelling wind and removing dampness, inducing menstruation to relieve menalgia.The merit that full side plays dampness removing pain relieving altogether, channels sootheing and network vessel quickening, silt of dispelling are invigorated blood circulation, is used for the treatment of wind and cold and wets the various rheumatic ostalgia that impatency meridians cause.
A kind of external used medicine for the treatment of rheumatic ostalgia provided by the invention has the following advantages:
1, compositions provided by the invention is safe and effective, has dampness removing pain relieving, channels sootheing and network vessel quickening, effect of invigorating blood circulation of becoming silted up of dispelling, and is used for the treatment of wind and cold and wets the various rheumatic ostalgia that impatency meridians cause.
2, the total effective rate of compositions treatment rheumatic ostalgia provided by the invention is 91.7%, and treatment rheumatic ostalgia is evident in efficacy.
3, Traditional Chinese medicine composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, the percent of the amount of alcohol in the present invention is percentage by volume, and v/v represents the volume ratio of solution.
Embodiment 1
Take yellow GUFENG 1kg, Herba Rubi blinii 0.3kg, little red brill 1kg, Fructus cinnamomi camphorae 1kg, Radix Rubi reflexi 1kg, lack elegant tight 0.3kg, nine layers of wind 0.5kg, purple nine Ns of 0.5kg, blue nine Ns of 1kg, Radix Toddaliae Asiaticae parasitic 0.3kg, Rhizoma valerianae latifoliae 0.3kg, yellow nine Ns of 1kg parts, black nine Ns of 1kg.Extracting in water 3 times, three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, three extraction times are respectively 3 hours, 2 hours, 1 hour, merge extractive liquid, filters, and when filtrate is concentrated into 70 DEG C, relative density is the clear paste of 1.25, add the flour of 1 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, puts into Mould Machining molding, to obtain final product.
Embodiment 2
Take yellow GUFENG 3kg, Herba Rubi blinii 1kg, little red brill 3kg, Fructus cinnamomi camphorae 3kg, Radix Rubi reflexi 3kg, lack elegant tight 1kg, nine layers of wind 2kg, purple nine Ns of 2kg, blue nine Ns of 3g, Radix Toddaliae Asiaticae parasitic 1kg, Rhizoma valerianae latifoliae 1kg, yellow nine Ns of 2kg parts, black nine Ns of 2kg.With 40% alcohol reflux 3 times, each ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours, 2 hours, 1 hour respectively extraction time, merge extractive liquid, filters, and when filtrate concentrates 60 DEG C, relative density is the extractum of 1.25, add the flour of 2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, puts into Mould Machining molding, to obtain final product.
Embodiment 3
Take yellow GUFENG 1.5kg, Herba Rubi blinii 0.5kg, little red brill 1.5kg, Fructus cinnamomi camphorae 1.5kg, Radix Rubi reflexi 1.5kg, lack elegant tight 0.5kg, nine layers of wind 1kg, purple nine Ns of 1kg, blue nine Ns of 1.5g, Radix Toddaliae Asiaticae parasitic 0.5kg, Rhizoma valerianae latifoliae 0.5kg, yellow nine Ns of 1.2kg parts, black nine Ns of 1.2kg.Extracting in water 3 times, three amount of water are equivalent to 12 times, 8 times, 6 times of medical material gross weight respectively, 3 hours, 2 hours, 1 hour respectively each extraction time, merge extractive liquid, filter, when filtrate is concentrated into 70 DEG C, relative density is the clear paste of 1.20, adds ethanol, makes alcohol content be 40%, leave standstill 24 hours, filter, it is the extractum of 1.10 that filtrate is concentrated into relative density when filtrate is concentrated into 70 DEG C, to obtain final product.
Embodiment 4
Take yellow GUFENG 2.5kg, Herba Rubi blinii 0.8kg, little red brill 2.5kg, Fructus cinnamomi camphorae 2.5kg, Radix Rubi reflexi 2.5kg, lack elegant tight 0.8kg, nine layers of wind 1.5kg, purple nine Ns of 1.5kg, blue nine Ns of 2.5g, Radix Toddaliae Asiaticae parasitic 0.8kg, Rhizoma valerianae latifoliae 0.8kg, yellow nine Ns of 1.8kg parts, black nine Ns of 1.8kg.With alcohol reflux 2 times, each concentration of alcohol is respectively 80%, 60%, and each ethanol consumption is respectively 10 times, 8 times of medical material total amount, extraction time is respectively 4 hours, 3 hours, merge extractive liquid, filters, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.10, to obtain final product.
Embodiment 5
Take yellow GUFENG 2kg, Herba Rubi blinii 0.6kg, little red brill 2kg, Fructus cinnamomi camphorae 2kg, Radix Rubi reflexi 2kg, lack elegant tight 0.6kg, nine layers of wind 1.2kg, purple nine Ns of 1.2kg, blue nine Ns of 2g, Radix Toddaliae Asiaticae parasitic 0.6kg, Rhizoma valerianae latifoliae 0.6kg, yellow nine Ns of 1.5kg parts, black nine Ns of 1.8kg.Get whole medical material, micronizing, cross 300 mesh sieves, mix homogeneously, adds the flour of 1 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, puts into Mould Machining molding, to obtain final product.
Embodiment 6 unguentum
Take yellow GUFENG 2.3kg, Herba Rubi blinii 0.7kg, little red brill 1.8kg, Fructus cinnamomi camphorae 2.3kg, Radix Rubi reflexi 1.8kg, lack elegant tight 0.7kg, nine layers of wind 0.8kg, purple nine Ns of 1.8kg, blue nine Ns of 2.3g, Radix Toddaliae Asiaticae parasitic 0.4kg, Rhizoma valerianae latifoliae 0.7kg, yellow nine Ns of 1.8kg parts, black nine Ns of 1.2kg.Get whole medical material, micronizing, cross 400 mesh sieves, mix homogeneously, adds the flour of 2 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, puts into Mould Machining molding, to obtain final product.
clinical trial is summed up
1 basic document
Observe rheumatic ostalgia patient 48 example, man 28 example, female 20 example, age 25-83 year, the course of disease gets rid of gestation and women breast-feeding their children, those who are allergic to this drug, late deformity, maimed person, disability person.Be diagnosed as rheumatic arthritis 16 example, rheumatoid arthritis 12 example, scapulohumeral periarthritis 4 example, bone matrix hyperplasia 8 example, prolapse of lumbar intervertebral disc 8 example.
2 Therapeutic Method
With the dough of the embodiment of the present invention 5, during use, dough is heated to 40-50 DEG C, fomentation affected part, repeated multiple times, within 1 week, be 1 course for the treatment of, after observing treatment, symptom changes situation, administration time 1 week-2 months.
3 curative effect judging standards
Effective: cardinal symptom disappears, symptom reduces > 2/3;
Effective: symptom reduces 1/3-2/3;
Invalid: symptom reduces < 1/3.
5 the results are shown in Table 1.
Table 1 efficacy result
Effective | Effectively | Invalid | Effective percentage (%) | |
Curative effect | 18 | 26 | 4 | 91.7 |
Clinical effectiveness shows: the external used medicine that the present invention treats rheumatic ostalgia is 91.7% to the total effective rate of rheumatic ostalgia patient, and result shows, the present invention has the curative effect of good treatment rheumatic ostalgia.
Model case:
Case 1: yellow XX, man, 48 years old.Make a definite diagnosis prolapse of lumbar intervertebral disc through hospital, self-treatment has no improvement for many years.Give the embodiment of the present invention 1 to treat, treat March, the state of an illness is almost recovered, and further consultation is better, then 1 cycle of after treatment, further consultation, and recovery from illness, follows up a case by regular visits to better so far.
Although above with general explanation, detailed description of the invention and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (8)
1. treat an external used medicine for rheumatic ostalgia, it is characterized in that it is prepared from by the raw material of Chinese medicine of following weight portion: yellow GUFENG 10-30 part, Herba Rubi blinii 3-10 part, little red brill 10-30 part, Fructus cinnamomi camphorae 10-30 part, Radix Rubi reflexi 10-30 part, lack elegant tight 3-10 part, nine layers of wind 5-20 part, purple nine Ns of 5-20 parts, blue nine Ns of 10-30 parts, the parasitic 3-10 part of Radix Toddaliae Asiaticae, Rhizoma valerianae latifoliae 3-10 part, yellow nine Ns of 10-20 parts, black nine Ns of 10-20 parts.
2. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 1, is characterized in that it is prepared from by the raw material of Chinese medicine comprising following weight portion: yellow GUFENG 15-25 part, Herba Rubi blinii 5-8 part, little red brills 15-25 part, Fructus cinnamomi camphorae 15-25 part, Radix Rubi reflexi 15-25 part, lack elegant tight 5-8 part, nine layers of wind 10-15 part, purple nine Ns of 10-15 parts, blue nine Ns of 15-25 parts, Radix Toddaliae Asiaticae parasitism 5-8 part, Rhizoma valerianae latifoliae 5-8 part, yellow nine Ns of 12-18 parts, black nine Ns of 12-18 parts.
3. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 1 or 2, is characterized in that its active component adopts the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.
4. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
5. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, 40-80% alcohol reflux 2-3 time is used after mixing, each ethanol consumption is 4-10 times of medical material total amount, extraction time is 1-4 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
6. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, add ethanol, alcohol content is made to be 40-70%, leave standstill 12-24 hour, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the extractum of 1.10-1.25, obtain active component.
7. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 1 or 2, it is characterized in that what described external used medicine was prepared from by the following method: get whole medical material, micronizing, cross 300-400 mesh sieve, mix homogeneously, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
8. the external used medicine for the treatment of rheumatic ostalgia as claimed in claim 3, it is characterized in that what described external used medicine was prepared from by the following method: get gained active component, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, put into Mould Machining molding, to obtain final product.
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