CN104888200A - Chinese medicine coat containing capsule granule for promoting insulin microcirculation - Google Patents

Abstract

The invention relates to a Chinese medicine coat containing capsule granule for promoting insulin microcirculation. The formula of the capsule granule comprises, by weight, 8-10% of Codonopsis pilosula, 3-5% of Coix lacroyma-jobi L. var. ma-yuen (Roman.), 4-7% of Coastal Glehnia Root, 3-5% of Kudzuvine Root Powder, 8-10% of Poria cocos, 4-7% of fructus aurantii, 3.5-4.5% of radix trichosanthis, 5-8% of Scrophularia ningpoensis, 2-4% of chicken's gizzard-membrane, 6-8% of panax notoginseng, 3.3-6.8% of pollen, 4-7% of Tuber Fleeceflower Stem, 5-6.3% of semen cuscutae, 4.8 - 7.5% of dragon bone, 5.5-5.9% of Schisandra chinensis, 3-6% of Coptis chinensis, 2-5% of Astragalus, 3-5% of parched malt, parched hawthorn and parched medicated leaven, 3-5% of Chinese angelica, 4-7% of Polygonatum, 2-4% of rhubarb, 2.5-4.5% of nardostachyos rhizome, 3.5-4.6% of dendrobium nobile, 1.5-2.5% of cassia twig, 1.5-2.5% of pearl, 1.5-2.5% of ophiopogon japonicus, 1.5-2.5% of radix rehmanniae, 1.5-2.5% of crude Chinese yam, 1.5-2.5% of common macrocarpium fruit, 1.5-2.5% of gecko, 1.5-2.5% of Cordyceps, and 1.5-2.5% of insulin microparticles. The capsule granule provided by the invention has the advantages of low cost, simple formula, good curative effect, convenient oral administration and the like.

Description

A kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin

[technical field]

The present invention relates to and a kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin.

[background technology]

The metabolic disease of diabetes to be one group with hyperglycemia be feature.Hyperglycemia be then due to defect of insulin secretion or its biological agent impaired, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, causes various tissue, particularly eye, kidney, heart, blood vessel, neural chronic lesion, dysfunction.The feature of diabetic microvascular complication is that capillary basement membrane thickens: normal basement membrane thick about 80 ~ 250nm, DM patient basal membrane thickening can reach 500 ~ 800nm.This kind of microangiopathies, often with Microcirculation abnormality, is the pathologic basis of concurrent many organ diseases.And for the system treatment method of diabetes, be generally Multiple Hospitalization treatment, long-term infusion mode therapy or injection mode insulin injection.But after long-term treatment, formed and rely on, and use transfusion and injection injection system, trouble is inconvenient.This department is by long-term practical studies, and by with Chinese medicinal granule, be aided with the insulin granule of trace, form hybrid particles capsule, both facilitated patient to take, curative effect is also remarkable.

[summary of the invention]

The object of the invention is to the defect for prior art and deficiency, there is provided a kind of structure simple, reasonable in design, easy to use a kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin, its adopts based on Chinese medicinal granule, promotes patient's microcirculation in human body, coordinate insulin microparticles auxiliary treatment, thus making patient recover healthy within a short period of time, it is low that it has cost, and formula is simple, good effect, the advantages such as taking convenience.

Of the present inventionly a kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin, its formula is as follows by weight percentage:

Radix Codonopsis 8-10%, grass pearl 3-5%, Radix Glehniae 4-7%, RADIX PUERARIAE 3-5%, Poria 8-10%, Fructus Aurantii 4-7%, to bloom powder 3.5-4.5%, Radix Scrophulariae 5-8%, Endothelium corneum 2-4%, Radix Notoginseng 6-8%, pollen 3.3-6.8%, Polygonm multiflorum Thunb village 4-7%, Semen Cuscutae 5-6.3%, Os Draconis 4.8-7.5%, Fructus Schisandrae Chinensis 5.5-5.9%, Rhizoma Coptidis 3-6%, Radix Astragali 2-5%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 3-5%, Radix Angelicae Sinensis 3-5%, Rhizoma Polygonati 4-7%, Radix Et Rhizoma Rhei 2-4%, Radix Et Rhizoma Nardostachyos 2.5-4.5%, Herba Dendrobii 3.5-4.6%, Ramulus Cinnamomi 1.5-2.5%, Margarita 1.5-2.5%, Radix Ophiopogonis 1.5-2.5%, Radix Rehmanniae 1.5-2.5%, Rhizoma Dioscoreae 1.5-2.5%, mountain cornel net 1.5-2.5%, stone tooth 1.5-2.5%, Cordyceps 1.5-2.5%, insulin microparticles 1.5-2.5%.

Its preparation adopts following method step:

1) by above-mentioned raw materials medicine: Radix Codonopsis, careless pearl, Radix Glehniae, RADIX PUERARIAE, Poria, Fructus Aurantii, powder of blooming, Radix Scrophulariae, Endothelium corneum, Radix Notoginseng, pollen, Polygonm multiflorum Thunb Tun, Semen Cuscutae, Os Draconis, Fructus Schisandrae Chinensis, Rhizoma Coptidis, the Radix Astragali, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Angelicae Sinensis, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Et Rhizoma Nardostachyos, Herba Dendrobii, Ramulus Cinnamomi, Margarita, Radix Ophiopogonis, the Radix Rehmanniae, Rhizoma Dioscoreae, mountain cornel net, stone tooth, Cordyceps, insulin microparticles 32 taste medicine are weighed by proportioning weight, then cleaning is placed in container, be uniformly mixed, obtain pending crude drug;

2) by step 1) in pending crude drug stirred by agitating device, pulverize, after sieving, be placed in again in drying room and carry out drying, the temperature of drying room is 50-65 degree, and drying time is 45 minutes, is then taken out to 30 minutes, shady and cool place, insert drying room again and toast 25 minutes, take out to obtain semi-finished stock medicine;

3) by step 2) in semi-finished stock medicine carry out again grinding to form fine powder, re-use agitating device and stir, stir formed granule, incapsulate, 0.5 gram every.

After adopting said structure, beneficial effect of the present invention is: of the present inventionly a kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin, it adopts based on Chinese medicinal granule, promote patient's microcirculation in human body, coordinate insulin microparticles auxiliary treatment, thus make patient recover healthy within a short period of time, it is low that it has cost, formula is simple, good effect, the advantages such as taking convenience.

[detailed description of the invention]

Describe the present invention in detail below by specific embodiment, illustrative examples wherein and explanation are only used for explaining the present invention, but not as a limitation of the invention.

A kind of described in this detailed description of the invention promotes the microcirculatory capsule particle containing Chinese medicine coat of insulin, and its formula is as follows by weight percentage:

Radix Codonopsis 8-10%, grass pearl 3-5%, Radix Glehniae 4-7%, RADIX PUERARIAE 3-5%, Poria 8-10%, Fructus Aurantii 4-7%, to bloom powder 3.5-4.5%, Radix Scrophulariae 5-8%, Endothelium corneum 2-4%, Radix Notoginseng 6-8%, pollen 3.3-6.8%, Polygonm multiflorum Thunb village 4-7%, Semen Cuscutae 5-6.3%, Os Draconis 4.8-7.5%, Fructus Schisandrae Chinensis 5.5-5.9%, Rhizoma Coptidis 3-6%, Radix Astragali 2-5%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 3-5%, Radix Angelicae Sinensis 3-5%, Rhizoma Polygonati 4-7%, Radix Et Rhizoma Rhei 2-4%, Radix Et Rhizoma Nardostachyos 2.5-4.5%, Herba Dendrobii 3.5-4.6%, Ramulus Cinnamomi 1.5-2.5%, Margarita 1.5-2.5%, Radix Ophiopogonis 1.5-2.5%, Radix Rehmanniae 1.5-2.5%, Rhizoma Dioscoreae 1.5-2.5%, mountain cornel net 1.5-2.5%, stone tooth 1.5-2.5%, Cordyceps 1.5-2.5%, insulin microparticles 1.5-2.5%.

Its preparation adopts following method step:

1) by above-mentioned raw materials medicine: Radix Codonopsis, careless pearl, Radix Glehniae, RADIX PUERARIAE, Poria, Fructus Aurantii, powder of blooming, Radix Scrophulariae, Endothelium corneum, Radix Notoginseng, pollen, Polygonm multiflorum Thunb Tun, Semen Cuscutae, Os Draconis, Fructus Schisandrae Chinensis, Rhizoma Coptidis, the Radix Astragali, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Angelicae Sinensis, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Et Rhizoma Nardostachyos, Herba Dendrobii, Ramulus Cinnamomi, Margarita, Radix Ophiopogonis, the Radix Rehmanniae, Rhizoma Dioscoreae, mountain cornel net, stone tooth, Cordyceps, insulin microparticles 32 taste medicine are weighed by proportioning weight, then cleaning is placed in container, be uniformly mixed, obtain pending crude drug;

2) by step 1) in pending crude drug stirred by agitating device, pulverize, after sieving, be placed in again in drying room and carry out drying, the temperature of drying room is 50-65 degree, and drying time is 45 minutes, is then taken out to 30 minutes, shady and cool place, insert drying room again and toast 25 minutes, take out to obtain semi-finished stock medicine;

3) by step 2) in semi-finished stock medicine carry out again grinding to form fine powder, re-use agitating device and stir, stir formed granule, incapsulate, 0.5 gram every.

Using method of the present invention is: every day 3 times, and each 4, warm water is bfore meals, until recovery from illness.This capsule can improve activity of islet cells, increases insulin secretion, and can increase the microcirculation of patient, thus increases the immunity of patient, thus has lower curative effect.

Of the present inventionly a kind ofly promote the microcirculatory capsule particle containing Chinese medicine coat of insulin, it adopts based on Chinese medicinal granule, promote patient's microcirculation in human body, coordinate insulin microparticles auxiliary treatment, thus making patient recover healthy within a short period of time, it is low that it has cost, and formula is simple, good effect, the advantages such as taking convenience.

The above is only better embodiment of the present invention, therefore all equivalences done according to structure, feature and the principle described in patent claim of the present invention change or modify, and are included in patent claim of the present invention.

Claims (1)

1. promote the microcirculatory capsule particle containing Chinese medicine coat of insulin, it is characterized in that: its formula is as follows by weight percentage:

Radix Codonopsis 8-10%, grass pearl 3-5%, Radix Glehniae 4-7%, RADIX PUERARIAE 3-5%, Poria 8-10%, Fructus Aurantii 4-7%, to bloom powder 3.5-4.5%, Radix Scrophulariae 5-8%, Endothelium corneum 2-4%, Radix Notoginseng 6-8%, pollen 3.3-6.8%, Polygonm multiflorum Thunb village 4-7%, Semen Cuscutae 5-6.3%, Os Draconis 4.8-7.5%, Fructus Schisandrae Chinensis 5.5-5.9%, Rhizoma Coptidis 3-6%, Radix Astragali 2-5%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 3-5%, Radix Angelicae Sinensis 3-5%, Rhizoma Polygonati 4-7%, Radix Et Rhizoma Rhei 2-4%, Radix Et Rhizoma Nardostachyos 2.5-4.5%, Herba Dendrobii 3.5-4.6%, Ramulus Cinnamomi 1.5-2.5%, Margarita 1.5-2.5%, Radix Ophiopogonis 1.5-2.5%, Radix Rehmanniae 1.5-2.5%, Rhizoma Dioscoreae 1.5-2.5%, mountain cornel net 1.5-2.5%, stone tooth 1.5-2.5%, Cordyceps 1.5-2.5%, insulin microparticles 1.5-2.5%,

Its preparation adopts following method step:

1) by above-mentioned raw materials medicine: Radix Codonopsis, careless pearl, Radix Glehniae, RADIX PUERARIAE, Poria, Fructus Aurantii, powder of blooming, Radix Scrophulariae, Endothelium corneum, Radix Notoginseng, pollen, Polygonm multiflorum Thunb Tun, Semen Cuscutae, Os Draconis, Fructus Schisandrae Chinensis, Rhizoma Coptidis, the Radix Astragali, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Angelicae Sinensis, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Et Rhizoma Nardostachyos, Herba Dendrobii, Ramulus Cinnamomi, Margarita, Radix Ophiopogonis, the Radix Rehmanniae, Rhizoma Dioscoreae, mountain cornel net, stone tooth, Cordyceps, insulin microparticles 32 taste medicine are weighed by proportioning weight, then cleaning is placed in container, be uniformly mixed, obtain pending crude drug;

2) by step 1) in pending crude drug stirred by agitating device, pulverize, after sieving, be placed in again in drying room and carry out drying, the temperature of drying room is 50-65 degree, and drying time is 45 minutes, is then taken out to 30 minutes, shady and cool place, insert drying room again and toast 25 minutes, take out to obtain semi-finished stock medicine;

3) by step 2) in semi-finished stock medicine carry out again grinding to form fine powder, re-use agitating device and stir, stir formed granule, incapsulate, 0.5 gram every.