CN104873775A - Traditional Chinese medicine composition for treating mammary gland hyperplasia - Google Patents
Traditional Chinese medicine composition for treating mammary gland hyperplasia Download PDFInfo
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Abstract
The invention relates to traditional Chinese medicine composition for treating mammary gland hyperplasia and effectively solve the pharmacy problem of mammary gland hyperplasia. According to the technical scheme, the traditional Chinese medicine composition comprises, by weight, 10-50 parts of Commelina hengalensis L., 5-10 parts of scutellaria indica, 5-15 parts of perilla stem, 5-15 parts of jasminum grandiflorum, 10-30 parts of fiveleaf akebia fruit, 5-15 parts of herba aristolochiae, 10-30 parts of oyster, 10-30 parts of turtle shell, 10-30 parts of bryozoatum, 5-15 parts of edible tulip, 5-20 parts of salviae miltiorrhizae, 5-15 parts of cowherb seed, 5-15 parts of tangerine seed and 5-15 parts of luffa. The traditional Chinese medicine composition is good in mammary gland hyperplasia curative effect, simple in recipe, cheap, good in use effect, and innovative.
Description
Technical field
The present invention relates to field of medicaments, particularly a kind of Chinese medicine composition for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is the modal cystic hyperplasia of breast of women, about has the women of 70%-80% to have cyclomastopathy in various degree according to investigations, is more common in the women in 25-45 year.The sickness rate of this disease was in the trend risen year by year in the last few years, and the age is in the trend of becoming younger; Become a large class disease of harm women life and health.Current treatment cyclomastopathy is mainly divided into doctor trained in Western medicine, the traditional Chinese medical science and operative treatment.Doctor trained in Western medicine concentrates on hormone therapy mostly in this disease for the treatment of, and side effect is large, and curative effect is unstable, and relapse rate is high, and curative effect is undesirable.Surgical operation is cured the symptoms, not the disease, and easily causes body to damage, and very easily recurs.Simple Chinese patent medicine DeGrain for oral administration, and relapse rate is high; And operative treatment has a big risk, wound is large, and patient is difficult to accept.Therefore, the improvement for the treatment of on the medicine of cyclomastopathy is the problem needing solution at present badly.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide a kind of Chinese medicine composition for the treatment of cyclomastopathy, effectively can solve the medication problem of cyclomastopathy.
The technical scheme that the present invention solves is, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 10-50 part, Herba Scutellariae indicae 5-10 part, Caulis Perillae 5-15 part, Flos jasmini 5-15 part, Fructus Akebiae 10-30 part, Herba Aristolochiae 5-15 part, Concha Ostreae 10-30 part, Carapax Trionycis 10-30 part, Pumex 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 5-15 part, Radix Salviae Miltiorrhizae 5-20 part, Semen Vaccariae 5-15 part, Semen Citri Reticulatae 5-15 part and Retinervus Luffae Fructus 5-15 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
The present invention has treatment cyclomastopathy effect preferably, and prescription is simple, low price, and result of use is good, is the innovation on treatment cyclomastopathy medicine.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
The present invention in the specific implementation, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 11 parts, Herba Scutellariae indicae 9 parts, Caulis Perillae 6 parts, Flos jasmini 14 parts, Fructus Akebiae 11 parts, Herba Aristolochiae 14 parts, Concha Ostreae 11 parts, Carapax Trionycis 29 parts, Pumex 11 parts, Pseudobulbus Cremastrae Seu Pleiones 14 parts, Radix Salviae Miltiorrhizae 6 parts, Semen Vaccariae 14 parts, Semen Citri Reticulatae 6 parts and Retinervus Luffae Fructus 14 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
Embodiment 2
The present invention in the specific implementation, can be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 30 parts, Herba Scutellariae indicae 7 parts, Caulis Perillae 10 parts, Flos jasmini 10 parts, Fructus Akebiae 20 parts, Herba Aristolochiae 10 parts, Concha Ostreae 20 parts, Carapax Trionycis 20 parts, Pumex 20 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Radix Salviae Miltiorrhizae 13 parts, Semen Vaccariae 10 parts, Semen Citri Reticulatae 10 parts and Retinervus Luffae Fructus 10 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
Embodiment 3
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 49 parts, Herba Scutellariae indicae 6 parts, Caulis Perillae 14 parts, Flos jasmini 6 parts, Fructus Akebiae 29 parts, Herba Aristolochiae 6 parts, Concha Ostreae 29 parts, Carapax Trionycis 11 parts, Pumex 29 parts, Pseudobulbus Cremastrae Seu Pleiones 6 parts, Radix Salviae Miltiorrhizae 19 parts, Semen Vaccariae 6 parts, Semen Citri Reticulatae 14 parts and Retinervus Luffae Fructus 6 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
Embodiment 4
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 10-29 part, Herba Scutellariae indicae 5-7 part, Caulis Perillae 5-9 part, Flos jasmini 5-9 part, Fructus Akebiae 10-19 part, Herba Aristolochiae 5-9 part, Concha Ostreae 10-19 part, Carapax Trionycis 10-19 part, Pumex 10-19 part, Pseudobulbus Cremastrae Seu Pleiones 5-9 part, Radix Salviae Miltiorrhizae 5-12 part, Semen Vaccariae 5-9 part, Semen Citri Reticulatae 5-9 part and Retinervus Luffae Fructus 5-9 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
Embodiment 5
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 31-50 part, Herba Scutellariae indicae 8-10 part, Caulis Perillae 11-15 part, Flos jasmini 11-15 part, Fructus Akebiae 21-30 part, Herba Aristolochiae 11-15 part, Concha Ostreae 21-30 part, Carapax Trionycis 21-30 part, Pumex 21-30 part, Pseudobulbus Cremastrae Seu Pleiones 11-15 part, Radix Salviae Miltiorrhizae 13-20 part, Semen Vaccariae 11-15 part, Semen Citri Reticulatae 11-15 part and Retinervus Luffae Fructus 11-15 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
In prescription of the present invention,
Horse Auricled Hedyotis Herb: nature and flavor are bitter; Cold, function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis to remove edema.Main calentura heating; Excessive thirst; Laryngopharynx swelling and pain; Hematodiarrhoea; Pyretic stranguria; Hemorrhoid; Furuncle carbuncle; Snake bite and insect sting;
Herba Scutellariae indicae: acrid in the mouth, property is put down.Function cures mainly: dispel the wind, and invigorates blood circulation, removing toxic substances, pain relieving.Control traumatic injury, spit blood, hemoptysis, carbuncle, furunculosis, acute throat trouble, toothache;
1. " the SHENGCAO property of medicine is standby to be wanted ": " control traumatic injury, snakebite, dispel the wind loose blood, strengthening bone and muscle, and detumescence, infusing drugs in wine is wonderful."
2. " Nanning City's medicine will ": " reducing swelling and alleviating pain, dispel the wind dissipating blood stasis.Control traumatic injury, snakebite, skin infection."
8. " Kweiyang medicinal herbs among the people ": " calming liver and clearing heat.Treating the liver hyperactivity of fire, irritated."
4. " Quanzhou book on Chinese herbal medicine ": " heat-clearing and toxic substances removing, Huang is moved back in detumescence, by blood removing blood stasis with potent drugs, removing pus and relieving carbuncle, cooling blood for hemostasis, throat.Cure mainly all larynxs Huang, also control lung-fire height dyspnea of heat type and cough, spit blood, hemoptysis is spat blood, and blood stasis is had a pain, and knife injury is hemorrhage, malignant boil carbuncle, tiger, lyssodexis."
Caulis Perillae: nature and flavor are pungent, temperature.Function cures mainly: regulating the flow of QI to ease the stomach, and pain relieving is antiabortive.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch is vomitted, frequent fetal movement;
Flos jasmini: nature and flavor are bitter is flat.Function cures mainly: circulation of qi promoting menstruction regulating and pain relieving, heat clearing away eliminating stagnation.For stomachache, hepatitis, menoxenia, dysmenorrhea, leukorrhagia, stomatitis, skin itching, orchitis, mastitis, tuberculous lymphadenitis;
Fructus Akebiae: nature and flavor hide micro-hardship, property is put down.Return liver, stomach, urinary bladder channel.Function cures mainly: dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Main stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor;
Herba Aristolochiae: nature and flavor are bitter, temperature.Return liver,spleen,kidney warp.Function cures mainly: promoting flow of QI and blood, inducing diuresis to remove edema.For gastral cavity ventral spine pain, arthralgia, edema during pregnancy.
Concha Ostreae: nature and flavor are salty, is slightly cold.Return liver, gallbladder, kidney channel.Function cures mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Carapax Trionycis: nature and flavor are salty, is slightly cold.Return liver, kidney channel.Function cures mainly: nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea , WEIJIA, chronic malaria malaria with splenomegaly.
Pumex: nature and flavor are salty, cold.Function cures mainly: removing heat from the lung and dissipating phlegm, hard masses softening and resolving.For cough due to lung-heat, yellowish thick sputum, spitting of blood, bronchitis, tuberculous lymphadenitis.
Pseudobulbus Cremastrae Seu Pleiones: nature and flavor are sweet, micro-pungent, cool.Return liver, spleen channel.Function cures mainly: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses.For carbuncle furunculosis, scrofula sucutaneous nodule, tuberculous lymphadenitis, snake bite and insect sting.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, tepor.Enter the heart, Liver Channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving.Control angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, lump in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.
Semen Vaccariae: nature and flavor are bitter is flat.Return liver, stomach warp.Function cures mainly: promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache;
Semen Citri Reticulatae: nature and flavor are bitter is flat.Return liver, kidney channel.Function cures mainly: regulate the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache;
Retinervus Luffae Fructus: nature and flavor are sweet is flat.Return lung, stomach, Liver Channel.Function cures mainly: dredging collateral, invigorates blood circulation, and dispels the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis.
Above-mentioned component science, reasonable compatibility, support mutually, is effective to treat cyclomastopathy, good effect, and drug safety, has no side effect, and stable curative effect is safe and reliable, and obtain sufficient proof through experiment, and regarding assay data is as follows:
1 clinical data
1.1 physical data
100 routine patients are divided into treatment group and matched group at random.Treatment group 50 example, age 20-50 year, 45.6 years old mean age; The course of disease 6 months-10 years, average 4.8 years; One-sided breast morbidity 18 example, bilateral breast morbidity 32 example; Mastalgia degree: slight 12 examples, moderate 29 example, severe 9 example.
Matched group 50 example, age 19-48 year, 44.7 years old mean age; The course of disease 6 months-11 years, average 4.5 years; One-sided breast morbidity 17 example, bilateral breast morbidity 33 example; Mastalgia degree: slight 10 examples, moderate 30 example, severe 10 example.Two groups, in the age course of disease, the state of an illness distribute close, through statistical procedures no significant difference (P>0.05), have comparability.
" Chinese medical disease Standardization of diagnosis and curative effect " that 1.2 diagnostic criterias are issued with reference to State Administration of Traditional Chinese Medicine for 1994 is drafted.(1) periodicity distending pain of the breast, mostly occurring or adding overweights premenstrua.(2) differing in size appears in side or bilateral breast, streak or diffusivity sheet block, and matter is tough, and border owes clear, has the tuberosity of tenderness, with surrounding tissue without adhesion.(3) local skin is without redness, and axillary lymph knot is without enlargement.(4) mammary gland infrared link scanning, molybdenum target photo, color Doppler ultrasound examination or pin are inhaled cytoscopy and are diagnosed as cyclomastopathy.
1.3 exclusion standards (1) get rid of other mastopathy such as breast carcinoma, mammary gland fibroadenoma.(2) serious condition and psychotics such as merging cardiovascular, Liver and kidney and hemopoietic system is got rid of.(3) gestation, women breast-feeding their children.(4) do not press predetermined treatment, cannot curative effect be judged, or the not congruent judgement person that affects the treatment of data.
2 therapeutic schemes
2.1 treatment groups take Chinese medicine of the present invention, and sooner or later respectively once, decoction being taken warmly, each 200-300ml, menstrual period withdraw, and within 3 months, are 1 course for the treatment of.
The oral BUPIXIAO PIAN of 2.2 matched group (the good nurse's board in Liaoning), every sheet 0.32g, each 6, every day 3 times, March was 1 course for the treatment of.Two groups of treatments period, other medicines that need not be relevant with treatment primary disease, add up curative effect after continuous use 3 menstrual cycle.
3 curative effect determinate standards
3.1 observation items observe clinical symptoms, sign change, infrared ray breast scanning, breast molybdenum target photo, color Doppler ultrasound examination before and after two groups of treatments, and a situation arises for blood, routine urinalysis, Liver and kidney function inspection and untoward reaction.
Criterion of therapeutical effect [the Wang Gentai that 3.2 criterions of therapeutical effect are formulated with reference to Society of Surgery of All-China Association of Traditional Chinese Medicine breast disease special topic group, Yang Limin, Zhu Feng, etc. the Chinese combination of Chinese and Western medicine magazine of newborn recovery treating cyclomastopathy 100 example [J], 1998,18 (7): 441] draft.
Cure: lump in breast and mastalgia disappear, and within after drug withdrawal 3 months, do not recur;
Effective; Lump in breast reduces more than 1/2, and mastalgia disappears;
Effective: lump in breast maximum gauge reduces less than 1/2, and mastalgia alleviates;
Invalid: lump in breast does not reduce, to increase on the contrary, hardening, or simple mastalgia is alleviated.
4 statistical procedures
By above-mentioned therapeutic scheme, the Chinese medicine that oral the present invention provides, curative effect is added up after continuous use 3 menstrual cycle, patient 50 example clinical definite being suffered to cyclomastopathy is treated, clinical cure 20 people, effective 19 people, effective 10 people, invalid 1 people, total effective rate 98%, matched group clinical cure 9 people, effective 13 people, effective 18 people, invalid 10 people, total effective rate 80%, treatment group is compared with matched group, * P < 0.05, * P < 0.01, difference has statistical significance, show this invention treatment by Chinese herbs cyclomastopathy Be very effective, reach clinical treatment object, and treatment group over the course for the treatment of, occur without obvious toxicity, blood before and after treatment, routine urinalysis, liver, renal function compares and is showed no ANOMALOUS VARIATIONS.
Table 1 a liang group cyclomastopathy patient treatment outcome compare [n (%)]
Compare with matched group, * P < 0.05, * * P < 0.01
5 conclusions
The present invention has treatment cyclomastopathy effect preferably, and prescription is simple, low price, and result of use is good, is the innovation on treatment cyclomastopathy medicine, has good economic and social benefit.
Claims (6)
1. treat the Chinese medicine composition of cyclomastopathy for one kind, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 10-50 part, Herba Scutellariae indicae 5-10 part, Caulis Perillae 5-15 part, Flos jasmini 5-15 part, Fructus Akebiae 10-30 part, Herba Aristolochiae 5-15 part, Concha Ostreae 10-30 part, Carapax Trionycis 10-30 part, Pumex 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 5-15 part, Radix Salviae Miltiorrhizae 5-20 part, Semen Vaccariae 5-15 part, Semen Citri Reticulatae 5-15 part, Retinervus Luffae Fructus 5-15 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
2. the Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 11 parts, Herba Scutellariae indicae 9 parts, Caulis Perillae 6 parts, Flos jasmini 14 parts, Fructus Akebiae 11 parts, Herba Aristolochiae 14 parts, Concha Ostreae 11 parts, Carapax Trionycis 29 parts, Pumex 11 parts, Pseudobulbus Cremastrae Seu Pleiones 14 parts, Radix Salviae Miltiorrhizae 6 parts, Semen Vaccariae 14 parts, Semen Citri Reticulatae 6 parts, Retinervus Luffae Fructus 14 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
3. the Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 30 parts, Herba Scutellariae indicae 7 parts, Caulis Perillae 10 parts, Flos jasmini 10 parts, Fructus Akebiae 20 parts, Herba Aristolochiae 10 parts, Concha Ostreae 20 parts, Carapax Trionycis 20 parts, Pumex 20 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Radix Salviae Miltiorrhizae 13 parts, Semen Vaccariae 10 parts, Semen Citri Reticulatae 10 parts, Retinervus Luffae Fructus 10 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
4. the Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 49 parts, Herba Scutellariae indicae 6 parts, Caulis Perillae 14 parts, Flos jasmini 6 parts, Fructus Akebiae 29 parts, Herba Aristolochiae 6 parts, Concha Ostreae 29 parts, Carapax Trionycis 11 parts, Pumex 29 parts, Pseudobulbus Cremastrae Seu Pleiones 6 parts, Radix Salviae Miltiorrhizae 19 parts, Semen Vaccariae 6 parts, Semen Citri Reticulatae 14 parts, Retinervus Luffae Fructus 6 parts, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
5. the Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 10-29 part, Herba Scutellariae indicae 5-7 part, Caulis Perillae 5-9 part, Flos jasmini 5-9 part, Fructus Akebiae 10-19 part, Herba Aristolochiae 5-9 part, Concha Ostreae 10-19 part, Carapax Trionycis 10-19 part, Pumex 10-19 part, Pseudobulbus Cremastrae Seu Pleiones 5-9 part, Radix Salviae Miltiorrhizae 5-12 part, Semen Vaccariae 5-9 part, Semen Citri Reticulatae 5-9 part, Retinervus Luffae Fructus 5-9 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
6. the Chinese medicine composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: horse Auricled Hedyotis Herb 31-50 part, Herba Scutellariae indicae 8-10 part, Caulis Perillae 11-15 part, Flos jasmini 11-15 part, Fructus Akebiae 21-30 part, Herba Aristolochiae 11-15 part, Concha Ostreae 21-30 part, Carapax Trionycis 21-30 part, Pumex 21-30 part, Pseudobulbus Cremastrae Seu Pleiones 11-15 part, Radix Salviae Miltiorrhizae 13-20 part, Semen Vaccariae 11-15 part, Semen Citri Reticulatae 11-15 part, Retinervus Luffae Fructus 11-15 part, by above-mentioned raw materials medicament mixed together, add water to submerge, soak 2h, intense fire is fried boiling, slow fire boiling 20min again, filter, medicinal residues add water to submerge again, intense fire is fried boiling, slow fire boiling 20min again, filter, merge twice filtrate, obtain.
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