CN101224290A - Chinese traditional medicine for treating breast nodules and preparing method thereof - Google Patents
Chinese traditional medicine for treating breast nodules and preparing method thereof Download PDFInfo
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- CN101224290A CN101224290A CNA2007103048074A CN200710304807A CN101224290A CN 101224290 A CN101224290 A CN 101224290A CN A2007103048074 A CNA2007103048074 A CN A2007103048074A CN 200710304807 A CN200710304807 A CN 200710304807A CN 101224290 A CN101224290 A CN 101224290A
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Abstract
The invention relates to a traditional Chinese medicine used for treating lumps in breast. The traditional Chinese medicine is prepared by the raw materials with the following weight proportion: 15-25 parts of radix bupleuri, 16-25 parts of radix curcumae, 15-25 parts of tangerine seed, 15-25 parts of unibract fritillary bulb, 15-25 parts of cape jasmine fruit, 15-25 parts of pseudoginseng, 15-25 parts of safflower, 15-25 parts of moutan bark, 5-15 parts of angelica dahurica, 15-25 parts of radix pseudostellariae, 15-25 parts of prepared stiff silkworm, 15-25 parts of prepared turtle shell, 15-25 parts of baked fossil bone, 15-25 parts of baked oyster, 15-25 parts of prepared pangolin and 5-15 parts of fried cowherb seed. The invention has reasonable compatibility, reliable curative effect, low cost, and no suffering is caused to patients, when the traditional Chinese medicine is taken by patients for treatment; therefore, the invention can be willingly accepted by patients. The medicine has simple and convenient preparation, can significant improve the effective rate for the treatment of stagnation of liver-qi and phlegm coagulation type nodules of breast; the invention is safe and has no toxic and side effect.
Description
(1) technical field
The present invention relates to a kind of Chinese medicine for the treatment of nodules of the breast, relate to its preparation method simultaneously.
(2) background technology
Nodules of the breast is with breast shape lump not of uniform size to be arranged, pain, and relevant with menstrual cycle is the benign proliferative diseases of the mammary gland tissue of main performance.The cause of nodules of the breast has clearly had following several: Liver depression and Qi stagnation, liver energy depression and phlegm stagnation card, pathogenic fire derived from stagnation of liver-QI card, syndrome of disharmony of Chong and Conception Channels.The symptom majority be outside breast on quadrant one flat lump is arranged, that lays one's hand on has a tough hard tubercle of beans size, tenderness is arranged, owe clearly on the lump border, with the surrounding tissue adhesion, the growth and decline with susceptible to anger whenever of lump in breast and pain increase the weight of before the menstruation of being everlasting, alleviate after the menstruation, be equivalent to cyclomastopathy and mammary gland fibroma.Wherein, the liver energy depression and phlegm stagnation type symptom mostly is lump in breast with the susceptible to anger growth and decline, with feeling of oppression over the chest and distention of hypochondrium, and kind strongly fragrant irritability, insomnia and dreamful sleep, vexed bitter taste, tongue fur BOHUANG, stringy and rolling pulse; How because of depression of liver-QI, dysfunction of the spleen in transportation, give birth in expectorant is turbid, coagulate expectorant for nuclear, follow through staying and gather in the Ruzhong, and make the Ruzhong caking, doctor trained in Western medicine adopts medicine and operative treatment more, but curative effect is very dissatisfied, and operation wound is big.
(3) summary of the invention
The object of the present invention is to provide a kind of Chinese medicine for the treatment of nodules of the breast, particularly at the Chinese medicine of liver energy depression and phlegm stagnation type nodules of the breast, determined curative effect, side effect is little, and is safe and reliable, and the patient is easy to accept.
The technical solution used in the present invention is as follows:
The Chinese medicine of treatment nodules of the breast, make by the raw material of following weight portion:
Radix Bupleuri 15-25 part Radix Curcumae 16-25 part Semen Citri Reticulatae 15-25 part Bulbus Fritillariae Cirrhosae 15-25 part Fructus Gardeniae 15-25 part Radix Notoginseng 15-25 part Flos Carthami 15-25 part Cortex Moutan 15-25 part Radix Angelicae Dahuricae 5-15 part Radix Pseudostellariae 15-25 part system Bombyx Batryticatus 15-25 part Carapax Trionycis (processed) 15-25 part Os Draconis (calcined) 15-25 part Concha Ostreae (calcined) 15-25 part Squama Manis (processed) 15-25 part Semen Vaccariae (parched) 5-15 part.
Described Chinese medicine is preferably made by the raw material of following weight portion:
Radix Bupleuri 18-20 part Radix Curcumae 18-20 part Semen Citri Reticulatae 18-20 part Bulbus Fritillariae Cirrhosae 18-22 part Fructus Gardeniae 18-20 part Radix Notoginseng 18-20 part Flos Carthami 18-20 part Cortex Moutan 18-22 part Radix Angelicae Dahuricae 8-12 part Radix Pseudostellariae 18-22 part system Bombyx Batryticatus 18-20 part Carapax Trionycis (processed) 18-20 part Os Draconis (calcined) 18-22 part Concha Ostreae (calcined) 18-22 part Squama Manis (processed) 18-20 part Semen Vaccariae (parched) 8-12 part.
Medicine of the present invention is according to the rule of treatment of the traditional Chinese medical science " dispersing the stagnated live-QI to relieve the stagnation of QI, dissipating phlegm and resolving masses, blood circulation promoting and blood stasis dispelling, YIN nourishing softening the hard mass ", selected Chinese medicine, reasonable compatibility.During raw material was formed, that Radix Bupleuri, Radix Curcumae, Semen Citri Reticulatae have was soothing the liver, regulate the flow of vital energy, the effect of resolving depression, pain relieving; The Bulbus Fritillariae Cirrhosae removing heat-phlegm, mass dissipating and swelling eliminating; The Fructus Gardeniae clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain; The Radix Notoginseng removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation; The Flos Carthami promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; The Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Radix Angelicae Dahuricae detumescence and apocenosis; The Radix Pseudostellariae air making-up and spleen enlivening; The Bombyx Batryticatus wind-expelling pain-stopping, dissipating phlegm and resolving masses; The Carapax Trionycis nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving; The Os Draconis suppressing the hyperactive liver and subsiding YANG, the convergence astringent or styptic treatment for spontaneous sweating; The Concha Ostreae suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving; The Squama Manis promoting blood circulation to remove obstruction in the collateral, detumescence and apocenosis; The Semen Vaccariae promoting blood circulation to restore menstrual flow, stimulating milk secretion, eliminating carbuncle.Above-mentioned all medicines share, long memorial liver resolving depression, dissipating phlegm and resolving masses altogether, and blood circulation promoting and blood stasis dispelling, the effect of YIN nourishing softening the hard mass has good curative effect to the liver energy depression and phlegm stagnation type nodules of the breast.
The Chinese medicine of described treatment nodules of the breast can be prepared into the watered pill or honeyed pill, the general one-tenth watered pill of preferred water.
The present invention also provides a kind of preparation to treat the method for the Chinese medicine of nodules of the breast as mentioned above, Carapax Trionycis (processed), Squama Manis (processed), Radix Notoginseng, the Bulbus Fritillariae Cirrhosae pulverize separately of getting the proportioning umber become fine powder, other raw materials are ground into fine powder after mixing, fine powder merges the back and crosses 100-200 mesh sieve, mixing, then with pharmaceutics on acceptable carrier make corresponding dosage form.
If be prepared into the watered pill, can be behind mixing be that adhesive preparation becomes ball with water, drying, per 6 is 1g, packing.
If be prepared into honeyed pill, can add the 90-110g refined honey by every 100g fine powder, make big honeyed pills, every ball 9g.
The present invention has following advantage with respect to prior art:
Compatibility of the present invention is reasonable, and patient takes this Chinese medicine and treats, and essentially no misery is taken like a shot, and curative effect is reliable, and expense is lower.Medicine is made simple and convenient, has significantly improved the treatment effective percentage of liver energy depression and phlegm stagnation type nodules of the breast, safe without toxic side effect.
(4) specific embodiment:
Below with specific embodiment and clinical case technical scheme of the present invention and curative effect are described, but protection scope of the present invention is not limited thereto:
Embodiment 1
Raw material is formed: 10 parts of 20 parts of Semen Vaccariae (parched)s of 10 parts of Radix Pseudostellariaes of 21 parts of Radixs Angelicae Dahuricae of 20 parts of Cortex Moutans of 18 parts of Flos Carthamis of 20 portions of Radix Notoginseng of 21 portions of Fructus Gardeniaes of 20 parts of Bulbus Fritillariae Cirrhosaes of 18 parts of Semen Citri Reticulataes of 18 portions of Radix Curcumaes of Radix Bupleuri, 21 parts of systems, 21 parts of Squama Manis (processed) of 21 parts of Concha Ostreae (calcined)s of 20 parts of Os Draconis (calcined)s of 20 parts of Carapax Trionycis (processed)s of Bombyx Batryticatus.
Get Carapax Trionycis (processed), Squama Manis (processed), Radix Notoginseng, Bulbus Fritillariae Cirrhosae and be ground into fine powder separately, be ground into fine powder after all the other 12 flavors mix, above-mentioned fine powder ground 100 mesh sieves after mixing, and mixing is used water pill, 60-80 ℃ of drying, and per 6 is 1g, packing, every bottle of 60g.
Embodiment 2
Raw material is formed: 12 parts of 20 parts of Semen Vaccariae (parched)s of 8 parts of Radix Pseudostellariaes of 23 parts of Radixs Angelicae Dahuricae of 20 parts of Cortex Moutans of 18 parts of Flos Carthamis of 18 portions of Radix Notoginseng of 22 portions of Fructus Gardeniaes of 20 parts of Bulbus Fritillariae Cirrhosaes of 20 parts of Semen Citri Reticulataes of 20 portions of Radix Curcumaes of Radix Bupleuri, 23 parts of systems, 25 parts of Squama Manis (processed) of 23 parts of Concha Ostreae (calcined)s of 18 parts of Os Draconis (calcined)s of 20 parts of Carapax Trionycis (processed)s of Bombyx Batryticatus.
Get Carapax Trionycis (processed), Squama Manis (processed), Radix Notoginseng, Bulbus Fritillariae Cirrhosae and be ground into fine powder separately, be ground into fine powder after all the other 12 flavors mix, above-mentioned fine powder ground 120 mesh sieves after mixing, and mixing adds the 110g refined honey by every 100g medicated powder and makes big honeyed pills, every ball 9g.
The clinical experiment effect
Strict screening 160 routine nodules of the breast patients (liver energy depression and phlegm stagnation type), experimental group 100 examples wherein, matched group 60 examples, 48 years old patient's mean age, average course of disease is 4 years.
Test group 100 examples are taken the watered pill of the present invention, a 6g, 3 times on the one.Matched group is taken BUPIXIAO PIAN (production of Liaoning Huan Ren pharmaceutical factory of traditional Chinese medicine), one time 6,3 times on the one.4 weeks were 1 course of treatment, serve on 3 courses of treatment.
The therapeutic evaluation standard: " disease of tcm diagnosis criterion of therapeutical effect " by State Administration of Traditional Chinese Medicine's issue carried out:
(1) recovery from illness: mastalgia and lump disappear not.
(2) effective: mastalgia alleviates or disappears, and lump dwindles.
(3) do not heal: lump in breast and pain no change.
In experimental group 100 examples, cure 53 examples, account for 53%; Effective 41 examples account for 41%; 6 examples more account for 6%; Total effective rate 94%.In matched group 60 examples, cure 4 examples, account for 6.6%; Effective 34 examples account for 56.7%; Invalid 22 examples account for 36.7%; Total effective rate 63.3%.
The result proves: the experimental group curative effect obviously is better than matched group.
Model case 1
Guo, the woman, 37 years old, married, people from Hebei, institute goes to a doctor in April, 1998.Private prosecution bilateral lump in breast 2 years is surplus, and pain is very unobvious, likes sulkyly at ordinary times, and lump is with the susceptible to anger growth and decline, vexed bitter taste, tongue fur BOHUANG, stringy and rolling pulse.Bilateral breast symmetry, left breast Nei Shang district and right breast central area are touched about 2 * 2 * 2cm lump respectively, and matter is tough, and the border is clear, and be movable good.Infrared diagnosis shows that bilateral breast blood vessel, latex dust divide and even, and sharpness of border, diagnostic result are mammary gland fibroma (liver energy depression and phlegm stagnation type).After take the watered pill of the present invention, a 6g, 3 times on the one, after the course of treatment, lump is contracted to 1 * 1 * 1cm, continues to take lump complete obiteration after 2 courses of treatment, recurrence again of check in 3 months after the drug withdrawal.
Model case 2
Yin, the woman, 38 years old, married, give birth to a woman, the teacher, institute goes to a doctor June calendar year 2001.Private prosecution bilateral distending pain of the breast 8 years is surplus, lump in breast 2 years, and lump changes with feelings will, vexed bitter taste, tongue fur BOHUANG, thready and stringy pulse.Have a medical check-up: bilateral breast symmetry, the bilateral breast is gone up quadrant outward can touch the lamellar lump, and thick about 2cm has tenderness, and matter is soft, and the border is clear, and infrared ray shows lump position blood vessel, latex dust density irregularity, irregular, and periphery is clear.Be diagnosed as bilateral breast hypertrophy disease (liver energy depression and phlegm stagnation type).After take the watered pill of the present invention, a 6g, 3 times on the one, pain relief after 1 course of treatment, the bilateral lump in breast all dwindles, and fully recovers after continuing to take 2 courses of treatment.
Claims (6)
1. the Chinese medicine of treatment nodules of the breast is characterized in that described Chinese medicine made by the raw material of following weight portion:
Radix Bupleuri 15-25 part Radix Curcumae 16-25 part Semen Citri Reticulatae 15-25 part Bulbus Fritillariae Cirrhosae 15-25 part Fructus Gardeniae 15-25 part Radix Notoginseng 15-25 part Flos Carthami 15-25 part Cortex Moutan 15-25 part Radix Angelicae Dahuricae 5-15 part Radix Pseudostellariae 15-25 part system Bombyx Batryticatus 15-25 part Carapax Trionycis (processed) 15-25 part Os Draconis (calcined) 15-25 part Concha Ostreae (calcined) 15-25 part Squama Manis (processed) 15-25 part Semen Vaccariae (parched) 5-15 part.
2. the Chinese medicine of treatment nodules of the breast as claimed in claim 1 is characterized in that being made by the raw material of following weight portion:
Radix Bupleuri 18-20 part Radix Curcumae 18-20 part Semen Citri Reticulatae 18-20 part Bulbus Fritillariae Cirrhosae 18-22 part Fructus Gardeniae 18-20 part Radix Notoginseng 18-20 part Flos Carthami 18-20 part Cortex Moutan 18-22 part Radix Angelicae Dahuricae 8-12 part Radix Pseudostellariae 18-22 part system Bombyx Batryticatus 18-20 part Carapax Trionycis (processed) 18-20 part Os Draconis (calcined) 18-22 part Concha Ostreae (calcined) 18-22 part Squama Manis (processed) 18-20 part Semen Vaccariae (parched) 8-12 part.
3. the Chinese medicine of treatment nodules of the breast as claimed in claim 1 or 2 is characterized in that described Chinese medicine is prepared into the watered pill, honeyed pill.
4. the Chinese medicine of treatment nodules of the breast as claimed in claim 3 is characterized in that described Chinese medicine is prepared into the watered pill.
5. the method for preparing the Chinese medicine of treatment nodules of the breast as claimed in claim 1 or 2, it is characterized in that described method is to get the Carapax Trionycis (processed) of proportioning umber, Squama Manis (processed), Radix Notoginseng, Bulbus Fritillariae Cirrhosae pulverize separately to become fine powder, other raw materials are ground into fine powder after mixing, fine powder merges the back and crosses 100-120 mesh sieve, mixing, makes corresponding dosage form with pharmaceutically acceptable carrier then.
6. the method for the Chinese medicine of preparation treatment nodules of the breast as claimed in claim 5 is characterized in that described Chinese medicine is prepared into the watered pill, and mixing after fine powder is sieved is that binding agent is prepared into the watered pill then with water.
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| CN2007103048074A CN101224290B (en) | 2007-12-28 | 2007-12-28 | Chinese traditional medicine for treating breast nodules and preparing method thereof |
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| CN2007103048074A CN101224290B (en) | 2007-12-28 | 2007-12-28 | Chinese traditional medicine for treating breast nodules and preparing method thereof |
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| CN101224290B CN101224290B (en) | 2010-07-14 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816339A (en) * | 2014-03-21 | 2014-05-28 | 张春花 | Traditional Chinese medicine granule for treating liver stagnation phlegm stasis type breast hyperplasia |
| CN104857340A (en) * | 2015-05-28 | 2015-08-26 | 潘剑崎 | Traditional Chinese medicine for treating hyperplasia of mammary glands |
| CN104873775A (en) * | 2015-05-28 | 2015-09-02 | 河南中医学院 | Traditional Chinese medicine composition for treating mammary gland hyperplasia |
| CN105148082A (en) * | 2015-10-13 | 2015-12-16 | 臧海阳 | Traditional Chinese medicine composition for treating nodules of breast caused by qi stagnation of liver and stomach |
| CN105688095A (en) * | 2016-04-13 | 2016-06-22 | 关汉辉 | Traditional Chinese medicine for treating breast nodules and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1060085C (en) * | 1998-06-08 | 2001-01-03 | 信国峰 | 'Kangruling' medicine mixture |
| CN1191849C (en) * | 2003-03-20 | 2005-03-09 | 陕西白鹿制药股份有限公司 | Chinese medicine for treating breast disease |
| CN100396322C (en) * | 2005-12-20 | 2008-06-25 | 付启荣 | Capsule for treating proliferation of mammary gland and its production method |
| CN100389815C (en) * | 2006-05-26 | 2008-05-28 | 雷秋模 | Medicine for treating mammary glands hyperplasia |
| CN100444889C (en) * | 2007-01-10 | 2008-12-24 | 河南太龙药业股份有限公司 | Chinese medicinal composition for treating mastopathy |
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2007
- 2007-12-28 CN CN2007103048074A patent/CN101224290B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816339A (en) * | 2014-03-21 | 2014-05-28 | 张春花 | Traditional Chinese medicine granule for treating liver stagnation phlegm stasis type breast hyperplasia |
| CN104857340A (en) * | 2015-05-28 | 2015-08-26 | 潘剑崎 | Traditional Chinese medicine for treating hyperplasia of mammary glands |
| CN104873775A (en) * | 2015-05-28 | 2015-09-02 | 河南中医学院 | Traditional Chinese medicine composition for treating mammary gland hyperplasia |
| CN104873775B (en) * | 2015-05-28 | 2018-06-01 | 河南中医学院 | A kind of Chinese medicine composition for treating the proliferation of mammary gland |
| CN105148082A (en) * | 2015-10-13 | 2015-12-16 | 臧海阳 | Traditional Chinese medicine composition for treating nodules of breast caused by qi stagnation of liver and stomach |
| CN105688095A (en) * | 2016-04-13 | 2016-06-22 | 关汉辉 | Traditional Chinese medicine for treating breast nodules and preparation method thereof |
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| CN101224290B (en) | 2010-07-14 |
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