CN104857438A - Traditional Chinese medicine preparation for relieving gastric poorly differentiated adenocarcinoma and preparation method of traditional Chinese medicine preparation - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for relieving gastric poorly differentiated adenocarcinoma. The traditional Chinese medicine preparation is prepared from astragalus membranaceus, rhizoma paridis chinensis, sun-dried ginseng, stir-fried largehead atractylodes rhizome, stir-fried white peony roots, rhodiola rosea, Chinese angelica, prepared rehmannia roots, rhizoma smilacis glabrae, Indian iphigenia bulb, barbed skullcap herb, rhizoma chuanxiong, rhizoma curcumae, wild buckwheat rhizome, suberect spatholobus stems, ganoderma lucidum, raw semen coicis, yangtao actinidia roots, wild chrysanthemum flowers, asiatic moonseed rhizome, flos sophorae and raw liquorice in a certain weight ratio. The traditional Chinese medicine preparation has the efficacy of clearing heat, removing toxicity, eliminating carbuncle, removing stasis, promoting the production of body fluid to relieve thirst, strengthening spleen and benefiting qi and can inhibit cancer cell spreading and strengthen physique of a patient, thereby controlling and relieving gastric poorly differentiated adenocarcinoma.

Description

A kind ofly alleviate Chinese medicine preparation of poorly differentiated adenocarcinoma cancer and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation alleviating poorly differentiated adenocarcinoma cancer, the invention still further relates to the preparation method of this Chinese medicine preparation.

Background technology

Poorly differentiated adenocarcinoma cancer, grade malignancy is relatively high, is usually in middle and advanced stage during discovery, and morbidity rapidly, and prognosis is poor.Therefore the treatment relative difficulty of poorly differentiated adenocarcinoma cancer.The treatment of early stage poorly differentiated adenocarcinoma cancer is based on excision, all clinical examinations are without obviously shifting sign, each important organ is without serious organic disease, and the poorly differentiated adenocarcinoma cancer patient that nutrition of whole body state, immunologic function can stand operation all should the chance of laparotomy exploration.Early stage poorly differentiated adenocarcinoma cancer Post operation, can according to excision whether completely, the difference of patient body tolerance degree and be aided with the methods such as chemicotherapy, Chinese medicine, immunization therapy to prevent recurrence.The treatment of middle and advanced stage poorly differentiated adenocarcinoma cancer advocates that multiple method is comprehensively carried out.There is diffusion transfer in middle and advanced stage poorly differentiated adenocarcinoma cancer, is difficult to carry out excision mostly, even if patient body can tolerate surgery, be also only palliative resction, now, the treatment of middle and advanced stage poorly differentiated adenocarcinoma cancer should in conjunction with multiple method, to learn from other's strong points to offset one's weaknesses, play advantage maximum separately.Poorly differentiated adenocarcinoma cancer is insensitive to chemotherapy, in the treatment for middle and advanced stage poorly differentiated adenocarcinoma cancer, can reduce cancerous protuberance to a certain extent, for chance is created in operation, after also can be used on palliative operation treatment, with symptom management development, extends life cycle.Poorly differentiated adenocarcinoma cancer has certain sensitivity to radiotherapy, and preoperative and postoperative all can be applied.Poorly differentiated adenocarcinoma cancer preoperative radiotherapy, can reduce cancerous protuberance, improves excision probability; Poorly differentiated adenocarcinoma cancer Postoperative radiation therapy, can eliminate the residual that may exist in case spline is moved and recurred.

These sick general or means of employing operation or Radiotherapy chemotherapy of current treatment, these means not only medical expense are high, and postoperative patients's physical recovery is slower, the health of meeting patient causes larger injury, Chinese medicine carries out dialectical treating from the angle of entirety, by the growth of inhibition tumor cell, improves patient's body constitution, increase patient's resistance, and then reach the object of disease therapy.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation alleviating poorly differentiated adenocarcinoma cancer, this Chinese medicine preparation has anticancer diffusion for poorly differentiated adenocarcinoma cancer, and strengthen patient's body constitution, cheap, have no side effect feature.

Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this alleviation poorly differentiated adenocarcinoma cancer.

Inventor is in clinical treatment practice for many years, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula alleviating the Chinese medicine preparation of poorly differentiated adenocarcinoma cancer repeatedly, the present invention selects the Radix Astragali, Rhizoma Paridis, Radix Ginseng, Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (parched), Radix Rhodiolae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Smilacis Glabrae, Pseudobulbus Cremastrae Seu Pleiones, Herba Scutellariae Barbatae, Rhizoma Chuanxiong, Rhizoma Curcumae, Rhizoma Fagopyri Dibotryis, Caulis Spatholobi, Ganoderma, Semen Coicis, Radix Actinidiae Chinensis, Flos Chrysanthemi Indici, Rhizoma Menispermi, Flos Sophorae, Radix Glycyrrhizae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, promoting the production of body fluid to quench thirst, effect of invigorating the spleen and benefiting QI, thus can effectively control to alleviate and treat poorly differentiated adenocarcinoma cancer.

The effect of Chinese medicine of the present invention:

Wherein:

The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.This product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.

Rhizoma Paridis: be the rhizome of liliaceous plant China Rhizoma Paridis Paris chinensis Franch..Nature and flavor: bitter, cold.Slightly poisonous.Effect: heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Epidemic encephalitis type B, stomachache, appendicitis, tuberculous lymphadenitis, tonsillitis, parotitis, mastitis, poisonous snake, insect-bite, sore swollen toxin.

Radix Ginseng: be the dry root of Araliaceae Radix Ginseng Panax ginseng C. A. Mey.Nature and flavor: flat, sweet, micro-hardship, tepor.Return spleen, lung, heart channel.Effect: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, Fructus Alpiniae Oxyphyllae of calming the nerves.Radix Ginseng can regulate the balance of central nervous system stimulant process and process of inhibition.

Rhizoma Atractylodis Macrocephalae (parched): be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor: bitter, sweet, temperature.Return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, the Rhizoma Atractylodis Macrocephalae can air making-up and spleen enlivening, again can dampness diuretic, is the key medicine of the spleen strengthening and damp drying.In the sweet temperature compensation of the Rhizoma Atractylodis Macrocephalae, can air making-up and spleen enlivening, also can strengthening superficial resistance to stop perspiration, and the Radix Astragali, ginseng compatibility, play the merit of spleen reinforcing lung altogether.To rule together asthenia, the weak person of overstrain.Rhizoma Atractylodis Macrocephalae antibacterial action is obvious: infusion has inhibitory action to acrothesium floccosum, star nocardia in vitro.Decoct also has inhibitory action to meningococcus.The Rhizoma Atractylodis Macrocephalae also has the function promoting hemopoietic.

Radix Paeoniae Alba (parched): be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Radix Paeoniae Alba (parched) is slightly slow than the Radix Paeoniae Alba property of medicine, based on the yin fluid astringing that nourishes blood.Be longer than the regulating liver-QI that nourishes blood after stir-fry, be used for the insufficiency of the spleen pain of the liver-yang hyperactivity person of rushing down, joint venture of enriching blood in this side, the spleen and stomach regulating, is conducive to the absorption of other drug.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " purgation of spleen excess heat, only abdomen pain, sealing rushes down, and receives adverse flow of liver-QI pain, takes good care of conscience spleen channel blood, relax through sending down the abnormal ascending QI, only irritability pain." " herbal classic " Radix Paeoniae, though respectively in vain not red, the two is master to some extent respectively.So seek and unravel silk it and cure mainly all diseases, one is that replenishing blood and nourishing liver spleen is Kidney-Yin, and receives and take the photograph the at random of temper, and throwing off restraint of irritability is horizontal, then the Radix Paeoniae Alba.

Radix Rhodiolae: be Crassulaceae Rhodida plant Radix Rhodiolae Rhodiola saera (Prain) Fu, with all herbal medicine.Nature and flavor: sweet, puckery, cold.Effect: QI invigorating lung heat clearing; Fructus Alpiniae Oxyphyllae is nourished heart; Hemostasis with astringents; Dissipating blood stasis for subsidence of swelling.Main deficiency of vital energy and physically weak; Fear of cold after being ill; Shortness of breath and fatigue; Cough due to lung-heat; Spitting of blood; Leucorrhea is suffered from diarrhoea; Traumatic injury; Burn and scald; Neurosis; Altitude sickness.

Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor: sweet, pungent, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis has inhibitory action to central nervous system, and volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores.Carry according to " book on Chinese herbal medicine is just ": " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation.

Radix Rehmanniae Preparata: be scrophulariaceae rehmannia glutinosa plant (Rehmannia glutinosa(Gdertn) Iibosch.ex Fisch. et Mey.) tuber form through Processing methods.Nature and flavor: sweet, tepor.Return liver, kidney channel.Effect: nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Radix Rehmanniae Preparata can be enriched blood YIN nourishing and liver-nourishing kidney-boosting, and all blood deficiency the moon loses, dizzy caused by deficiency of the liver and kindey, all can apply.

Rhizoma Smilacis Glabrae: be the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..Nature and flavor: sweet, light are flat.Return liver, stomach warp.Effect: removing damp-heat; Let out turbid removing toxic substances; Easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain." book on Chinese herbal medicine justice ": Rhizoma Smilacis Glabrae, dampness removing reduces phlegm and internal heat, and can enter network, searches to pick and damp and hot accumulates poison.It separates hydrargyrum, Calomelas poison person, and it is up that receive poison with ascending, and this leads as business under oozing profit, therefore specially control Fructus Myricae rubrae skin infection, gos deep into hundred networks, arthralgia, even rotten, and poison fire is up again, and throat pain is burst, and all dislike disease.

Pseudobulbus Cremastrae Seu Pleiones: be the dry pseudobulb of orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides (Franch.) Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Nature and flavor: sweet, pungent, cold, mild toxicity.Return liver, stomach, lung meridian.Effect: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.This product has the merit of detoxicating and resolving stagnation of pathogens detumescence, in recent years this product Guang general ground Yu mass in the abdomen mass in the abdomen and kinds of tumors.

Herba Scutellariae Barbatae: be the dry herb of labiate Herba Scutellariae Barbatae Scutellaria barbata D. Don.Nature and flavor: pungent, bitter, cold.Return lung, liver, kidney channel.Effect: heat-clearing and toxic substances removing, dissipating blood stasis stops blooding, inducing diuresis to remove edema.This product is former in the disease such as venom and sore and toxic; In recent years clinically for diseases such as hepatitis, hepatomegaly, cirrhotic ascites, cancerous protuberance and haematemesis bleeding due to traumies.For pulmonary carcinoma, pharmaceutical research, its bacteriostasis is remarkable, all has inhibitory action to staphylococcus aureus, shigella flexneri, Bacillus typhi, bacillus pyocyaneus, escherichia coli.

Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is led to, can top, up mountain peak, assigns the sea of blood, outer thorough fur, bypass extremity, can invigorate blood circulation and can circulation of qi promoting, and it is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.Rhizoma Chuanxiong has obvious sedation.The in vitro testses such as antibacterial action: Rhizoma Chuanxiong has inhibitory action to large intestine, dysentery (Song Nei Shi), distortion, green pus, typhoid fever, Salmonella paratyphi and vibrio cholera etc.Rhizoma Chuanxiong water logging agent (1:3) also has inhibitory action to some pathogenic dermatophytes in vitro.

Rhizoma Curcumae: be monocotyledon Zingiberaceae Zingiberaceae Rhizoma Curcumae Curcuma phaeocaulis Val., or RADIX CURCUMAE (also known as Curcuma wenyujin) C. wenyujin Y. H. Chen et C. Ling, the dry rhizome of Guangxi zedoary (also known as C. kwangsinensis) C.kwangsiensis S. lee et C. F. Liang.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: removing blood stasis, promoting the circulation of QI to relieve pain.Often join Rhizoma Sparganii.Antibacterial action: Rhizoma Curcumae volatile oil in vitro can suppress staphylococcus aureus.The growth of beta hemolytic streptococcus, escherichia coli, Bacillus typhi, vibrio cholera etc.Rhizoma Curcumae has the effect of directly killing oncocyte.

Rhizoma Fagopyri Dibotryis: be polygonaceae plant Rhizoma Fagopyri Dibotryis Fagopyrum dibotrys(D.Don) dry rhizome of Hara.Nature and flavor: micro-pungent, puckery, cool.Return lung meridian.Effect: heat-clearing and toxic substances removing, evacuation of pus blood stasis dispelling.For lung abscess, measles pneumonia, peritonsillar abscess.Main lung abscess; Lung-heat cough with asthma; Laryngopharynx swelling and pain; Dysentery; Rheumatism arthromyodynia; Traumatic injury; Carbuncle cancer.There is significantly anticancer and antibacterial effect clinically.

Caulis Spatholobi: be the dry rattan of pulse family Leguminosae plant spatholobus suberectus Spatholobus suberectusDunn.Nature and flavor: bitter, sweet, temperature.Return liver, kidney channel.Effect: enrich blood, invigorates blood circulation, dredging collateral.This product promoting the circulation of blood is nourished blood, relaxing muscles and tendons and activating QI and blood in the collateral, for treatment passages through which vital energy circulates is not smooth, and the common medicine of channels discord disease.

Ganoderma: be On Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Ganoderma lucidum(Leyss.ex Fr.) Karst. or Ganoderma Ganoderma sinense Zhao, the dry sporophore of Xu et Zhang.Nature and flavor: sweet are flat.GUIXIN, lung, liver, kidney channel.Effect: invigorating QI and tranquilization, relieving cough and asthma.For dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma.Shi Zhen tastes doubtful: sesame is that rotten residual air given birth to, and goes to live in the household of one's in-laws on getting married, and all think Ganoderma at all times as life tumor, and take can be celestial for cloud again, is really circuitous wrong.Closely be read as the speech of formula, begin to know that first obtaining my institute's wish says, its principle one also.Necromancer is with the long-pending wet place of wood again, medication Fu it, i.e. raw multicolored sesame.In Jiajin Year, Wang Jin tastes raw to offer generation ancestor.The non-speaker of this former times people, can not know.

Semen Coicis: be the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.Nature and flavor: sweet, light, cool.Return spleen, stomach, lung meridian.Effect: spleen invigorating eliminating dampness by diuresis, eliminating impediment pain relieving, clearing away heat and discharging pus.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.This product can eliminating dampness by diuresis, again can relaxing muscles and tendons arteries and veins, and slow contraction is anxious, is good at the damp dispelling muscle muscles and bones, therefore is used for arthralgia chiefly caused by damp pathogen, because it is cool in nature, therefore be more suitable for for damp and hot arthralgia pain

Radix Actinidiae Chinensis: be the root of Fructus actinidiae chinensis section plant Fructus actinidiae chinensis.Nature and flavor: sour, puckery, cool.Effect: heat-clearing and toxic substances removing, expelling wind and removing dampness, diuresis is stopped blooding.For rheumatic ostalgia, and the disease such as jaundice.Be used in various cancer, the cancer applications especially for intestines and stomach aspect is more.

Flos Chrysanthemi Indici: be the dry capitulum of feverfew Herba Dendranthematis indici Chrysanthemum indicum L..Nature and flavor: bitter, pungent, are slightly cold.Return liver, heart channel.Effect: heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain, has a headache dizzy.The merit of Flos Chrysanthemi heat-clearing and toxic substances removing is excellent, is surgery key medicine, is mainly used in the disease of pathopyretic ulcer, red and swollen heat pain, especially has good efficacy, both oral administrations especially, can mash external application again for the furuncle poison that swells and ache.The product fit applications of the normal and heat-clearing and toxic substances removing such as Herba Violae, Herba Taraxaci clinically.

Rhizoma Menispermi: be the dry rhizome of menispermaceous plants Caulis menispermi Menispermum dauricum DC..Nature and flavor: bitter, cold; Slightly poisonous.Return lung, stomach, large intestine channel.Effect: heat-clearing and toxic substances removing, wind-expelling pain-stopping.For laryngopharynx swelling and pain, enteritis and dysentery, rheumatic arthralgia.For laryngopharynx swelling and pain, enteritis and dysentery, rheumatic arthralgia.

Flos Sophorae: be the dry flower and alabastrum of leguminous plant Chinese scholartree Sophora japonica L..Nature and flavor: bitter, are slightly cold.Return liver, large intestine channel.Effect: cooling blood for hemostasis, purging liver-fire.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.

Radix Glycyrrhizae: be the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza Glabra L..Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.

Side's solution of the present invention is: Radix Astragali inducing diuresis to remove edema in side, the evacuation of pus of holder skin ulcer, Rhizoma Paridis heat-clearing and toxic substances removing, reducing swelling and alleviating pain, Radix Ginseng invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI, dampness diuretic, Radix Paeoniae Alba (parched) is enriched blood easing the affected liver, a few taste is monarch drug altogether above, Rhizoma Paridis has the effect of obvious anticancer, the Radix Astragali, Radix Ginseng promoting the production of body fluid to quench thirst, invigorating the spleen to benefit the lung, patient is helped to regulate metabolism, promote, help gastric digestion, alleviate stomach burden, five kinds of Chinese medicine share, increase drug effect, reach the effect controlling and alleviate the poorly differentiated adenocarcinoma metastasis of cancer, and then reach the object for the treatment of.The lung heat clearing of Radix Rhodiolae QI invigorating, dissipating blood stasis for subsidence of swelling, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, Rhizoma Smilacis Glabrae removing damp-heat, lets out turbid removing toxic substances, Pseudobulbus Cremastrae Seu Pleiones, Herba Scutellariae Barbatae heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, above Six-element is ministerial drug altogether, and Pseudobulbus Cremastrae Seu Pleiones and Herba Scutellariae Barbatae increase the effect of monarch drug heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, are used for the growth of Tumor suppression, another a few taste blood circulation promoting and enriching just fast medicine arrives the time of focus, promotes the recovery of patient.Rhizoma Chuanxiong blood-activating and qi-promoting, Rhizoma Curcumae removing blood stasis, promoting the circulation of QI to relieve pain, Rhizoma Fagopyri Dibotryis heat-clearing and toxic substances removing, evacuation of pus blood stasis dispelling, Caulis Spatholobi is enriched blood and invigorates blood circulation, Ganoderma invigorating QI and tranquilization, Semen Coicis spleen invigorating eliminating dampness by diuresis, Radix Actinidiae Chinensis heat-clearing and toxic substances removing, Flos Chrysanthemi Indici, Rhizoma Menispermi heat-clearing and toxic substances removing, Flos Sophorae cooling blood for hemostasis, a few taste is adjuvant drug altogether above, while increasing drug effect, do not forget nourishing YIN for suppressing the hyperactive YANG, replenishing kidney, strengthening waist, strengthen the body constitution of patient, increase the resistance of patient, and then accelerate patient's improvement.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, priming return through, for making medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, promoting the production of body fluid to quench thirst, invigorating the spleen and benefiting QI, effectively can control growth and the diffusion of cancerous cell, and then reach and alleviate and treat the effect of poorly differentiated adenocarcinoma cancer.

Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Astragali 15-25 part, Rhizoma Paridis 10-20 part, Radix Ginseng 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 15-25 part, Radix Paeoniae Alba (parched) 10-20 part, Radix Rhodiolae 15-25 part, Radix Angelicae Sinensis 13-23 part, Radix Rehmanniae Preparata 15-25 part, Rhizoma Smilacis Glabrae 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 15-25 part, Herba Scutellariae Barbatae 19-29 part, Rhizoma Chuanxiong 7-17 part, Rhizoma Curcumae 7-17 part, Rhizoma Fagopyri Dibotryis 7-17 part, Caulis Spatholobi 13-23 part, Ganoderma 13-23 part, Semen Coicis 25-35 part, Radix Actinidiae Chinensis 10-20 part, Flos Chrysanthemi Indici 5-15 part, Rhizoma Menispermi 10-20 part, Flos Sophorae 7-17 part, Radix Glycyrrhizae 4-14 part.

Wherein be preferably: the Radix Astragali 20 parts, Rhizoma Paridis 15 parts, Radix Ginseng 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Radix Paeoniae Alba (parched) 15 parts, Radix Rhodiolae 20 parts, Radix Angelicae Sinensis 18 parts, Radix Rehmanniae Preparata 20 parts, Rhizoma Smilacis Glabrae 20 parts, Pseudobulbus Cremastrae Seu Pleiones 20 parts, Herba Scutellariae Barbatae 24 parts, Rhizoma Chuanxiong 12 parts, Rhizoma Curcumae 12 parts, Rhizoma Fagopyri Dibotryis 12 parts, Caulis Spatholobi 18 parts, Ganoderma 18 parts, Semen Coicis 30 parts, Radix Actinidiae Chinensis 15 parts, Flos Chrysanthemi Indici 10 parts, Rhizoma Menispermi 15 parts, 12 parts, Flos Sophorae, Radix Glycyrrhizae 9 parts.

Medicine of the present invention can adopt the conventional fabrication process of Chinese medicine preparation, can be made into said dosage form on any one pharmaceutics, as pill, powder, tablet, capsule, granule, syrup, oral liquid etc.Such as these crude drug grind into fine powder mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.

The preferred preparation method of the present invention is decoction, and its preparation method is as follows:

Step one: by weight proportion of the present invention, take the Radix Astragali, Rhizoma Smilacis Glabrae, Rhizoma Curcumae, Rhizoma Fagopyri Dibotryis, Radix Actinidiae Chinensis, Rhizoma Menispermi put into marmite, add the water of 2-3 centimetre, after being fried boiling with high heat, again with 30-40 minute at a simmer, filter, obtain filtrate, in residue medicinal residues, add the water of 3-4 centimetre, add Radix Rhodiolae, Radix Angelicae Sinensis, Pseudobulbus Cremastrae Seu Pleiones, Herba Scutellariae Barbatae, Rhizoma Chuanxiong, Caulis Spatholobi, and the Semen Coicis bound up with gauze decocts 20 minutes, finally add Flos Chrysanthemi Indici, Flos Sophorae, Radix Glycyrrhizae decoct 10 minutes, filter, obtain filtrate, merge twice filtrate, for subsequent use;

Step 2: by weight proportion of the present invention, take Radix Ginseng, Ganoderma puts into marmite, adds the water of 3-4 centimetre, with slow fire boiling 50 minutes, filters, obtains filtrate, for subsequent use;

Step 3: by weight proportion of the present invention, takes Rhizoma Paridis and puts into marmite, adds the water of 3 cm, decocts 30 minutes, filters, obtains filtrate, for subsequent use;

Step 4: by weight proportion of the present invention, takes Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (parched), Radix Rehmanniae Preparata pulverizing, is ground to 120 mesh sieves, for subsequent use;

Step 5: by the medicinal liquid mixing in step one, step 2, step 3 together, then add the medicated powder Homogeneous phase mixing of step 4, both the Chinese medicine decoction of alleviation poorly differentiated adenocarcinoma cancer of the present invention.

Medicine of the present invention has effect of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, promoting the production of body fluid to quench thirst, invigorating the spleen and benefiting QI, and anticancer diffusion, strengthen patient's body constitution, cheap, have no side effect, the mode that this Chinese medicine preparation adopts is treated and can be reduced Western medicine and chemicotherapy to the injury of patient body, alleviate the slight illness of patient, according to clinical 60 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 81.7%, two the total effective rate course for the treatment of 95%.

Detailed description of the invention

Embodiment one, the Radix Astragali 15 parts, Rhizoma Paridis 10 parts, Radix Ginseng 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Radix Paeoniae Alba (parched) 10 parts, Radix Rhodiolae 15 parts, Radix Angelicae Sinensis 13 parts, Radix Rehmanniae Preparata 15 parts, Rhizoma Smilacis Glabrae 15 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Herba Scutellariae Barbatae 19 parts, Rhizoma Chuanxiong 7 parts, Rhizoma Curcumae 7 parts, Rhizoma Fagopyri Dibotryis 7 parts, Caulis Spatholobi 13 parts, Ganoderma 13 parts, Semen Coicis 25 parts, Radix Actinidiae Chinensis 10 parts, Flos Chrysanthemi Indici 5 parts, Rhizoma Menispermi 10 parts, 7 parts, Flos Sophorae, Radix Glycyrrhizae 4 parts.

Embodiment two, the Radix Astragali 20 parts, Rhizoma Paridis 15 parts, Radix Ginseng 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Radix Paeoniae Alba (parched) 15 parts, Radix Rhodiolae 20 parts, Radix Angelicae Sinensis 18 parts, Radix Rehmanniae Preparata 20 parts, Rhizoma Smilacis Glabrae 20 parts, Pseudobulbus Cremastrae Seu Pleiones 20 parts, Herba Scutellariae Barbatae 24 parts, Rhizoma Chuanxiong 12 parts, Rhizoma Curcumae 12 parts, Rhizoma Fagopyri Dibotryis 12 parts, Caulis Spatholobi 18 parts, Ganoderma 18 parts, Semen Coicis 30 parts, Radix Actinidiae Chinensis 15 parts, Flos Chrysanthemi Indici 10 parts, Rhizoma Menispermi 15 parts, 12 parts, Flos Sophorae, Radix Glycyrrhizae 9 parts.

Embodiment three, the Radix Astragali 25 parts, Rhizoma Paridis 20 parts, Radix Ginseng 20 parts, Rhizoma Atractylodis Macrocephalae (parched) 25 parts, Radix Paeoniae Alba (parched) 20 parts, Radix Rhodiolae 25 parts, Radix Angelicae Sinensis 23 parts, Radix Rehmanniae Preparata 25 parts, Rhizoma Smilacis Glabrae 25 parts, Pseudobulbus Cremastrae Seu Pleiones 25 parts, Herba Scutellariae Barbatae 29 parts, Rhizoma Chuanxiong 17 parts, Rhizoma Curcumae 17 parts, Rhizoma Fagopyri Dibotryis 17 parts, Caulis Spatholobi 23 parts, Ganoderma 23 parts, Semen Coicis 35 parts, Radix Actinidiae Chinensis 20 parts, Flos Chrysanthemi Indici 15 parts, Rhizoma Menispermi 20 parts, 17 parts, Flos Sophorae, Radix Glycyrrhizae 14 parts.

Here is the clinical statistics data that patient uses medicine of the present invention:

One, physical data

Accept out-patient 60 example for medical treatment, wherein male 28 example, women 32 example, M-F 1:1.14,40 years old mean age, course of disease some months is not to many decades etc.

Two, Therapeutic Method:

According to Medications Example two of the present invention, weighting raw materials (daily dose), decocting, filter and remove residue, takes at twice, within 10th, is a course for the treatment of.

Three, efficacy assessment standard:

1, effective: body constitution strengthens, and the clinical symptoms such as upper abdomen dull pain, anemia disappear completely, CT examination display stomach kind reduces, and other positions do not find nascent tumor.

2, effective: body constitution strengthens to some extent, upper abdomen dull pain, full abdomen, anemia phenomenon are alleviated to some extent, and CT shows tumor stomach and do not increase, and other positions do not find nascent tumor.

3, invalid: symptom does not change, tumor stomach increases, or other positions find nascent tumor.

Four, therapeutic outcome statistics

Wherein: total effective rate=obvious effective rate+effective percentage

Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness in control and alleviation poorly differentiated adenocarcinoma cancer, is worth promoting in clinical practice.

Model case and curative effect:

Case one, grandson patient, female, 52 years old, patient suffers from chronic gastritis always, there is upper abdomen dull pain in the recent period, glutted discomfort, poor appetite, the phenomenon of anemia is also had time serious, patient removes examination in hospital, be diagnosed as poorly differentiated adenocarcinoma cancer, patient is unwilling to be treated surgically, determine to adopt Chinese medicine expectant treatment, adopt made preparation in the embodiment of the present invention two, and selected preparation method, after patient takes a course for the treatment of, patient mental's state, all are normal for appetite etc., continue to take two courses for the treatment of, patient clinical symptom, the phenomenons such as anemia disappear, examination in hospital tumor is gone obviously to reduce, patient continues to take a period of time, the state of an illness is controlled, tumor reduces not diffusing phenomenon gradually.

Case two, patient Wu, man, 59 years old, patient is because of stomach discomfort, and engender the phenomenon of lean body mass, health occurs significantly uncomfortable, remove examination in hospital, lab testing final result is poorly differentiated adenocarcinoma cancer, family numbers of patients does not tell patient's truth, do not wish that patient is put, chemotherapy and operative treatment, wish to conceal conditions of patients, so adopt the method for the treatment of by Chinese herbs, patient adopts made preparation in the embodiment of the present invention two, and selected preparation method, after several days, poorly differentiated adenocarcinoma cancerous symptom obviously alleviates, continue two courses for the treatment of of use, patient's appetite obviously increases, other clinical symptoms are eased, body weight also increases to some extent, patient is another directly adhere to taking a period of time after, hospital is gone to check, find that tumor disappears substantially, do not find nascent tumor.

Claims (4)

1. alleviate the Chinese medicine preparation of poorly differentiated adenocarcinoma cancer for one kind, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Astragali 15-25 part, Rhizoma Paridis 10-20 part, Radix Ginseng 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 15-25 part, Radix Paeoniae Alba (parched) 10-20 part, Radix Rhodiolae 15-25 part, Radix Angelicae Sinensis 13-23 part, Radix Rehmanniae Preparata 15-25 part, Rhizoma Smilacis Glabrae 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 15-25 part, Herba Scutellariae Barbatae 19-29 part, Rhizoma Chuanxiong 7-17 part, Rhizoma Curcumae 7-17 part, Rhizoma Fagopyri Dibotryis 7-17 part, Caulis Spatholobi 13-23 part, Ganoderma 13-23 part, Semen Coicis 25-35 part, Radix Actinidiae Chinensis 10-20 part, Flos Chrysanthemi Indici 5-15 part, Rhizoma Menispermi 10-20 part, Flos Sophorae 7-17 part, Radix Glycyrrhizae 4-14 part.

2. the Chinese medicine preparation of alleviation poorly differentiated adenocarcinoma cancer according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: the Radix Astragali 20 parts, Rhizoma Paridis 15 parts, Radix Ginseng 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Radix Paeoniae Alba (parched) 15 parts, Radix Rhodiolae 20 parts, Radix Angelicae Sinensis 18 parts, Radix Rehmanniae Preparata 20 parts, Rhizoma Smilacis Glabrae 20 parts, Pseudobulbus Cremastrae Seu Pleiones 20 parts, Herba Scutellariae Barbatae 24 parts, Rhizoma Chuanxiong 12 parts, Rhizoma Curcumae 12 parts, Rhizoma Fagopyri Dibotryis 12 parts, Caulis Spatholobi 18 parts, Ganoderma 18 parts, Semen Coicis 30 parts, Radix Actinidiae Chinensis 15 parts, Flos Chrysanthemi Indici 10 parts, Rhizoma Menispermi 15 parts, 12 parts, Flos Sophorae, Radix Glycyrrhizae 9 parts.

3. the Chinese medicine preparation of alleviation poorly differentiated adenocarcinoma cancer according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.

4. alleviate the preparation method of the Chinese medicine preparation of poorly differentiated adenocarcinoma cancer for one kind, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, take the Radix Astragali, Rhizoma Smilacis Glabrae, Rhizoma Curcumae, Rhizoma Fagopyri Dibotryis, Radix Actinidiae Chinensis, Rhizoma Menispermi puts into marmite, add the water of 2-3 centimetre, after being fried boiling with high heat, again with 30-40 minute at a simmer, filter, obtain filtrate, the water of 3-4 centimetre is added in residue medicinal residues, add Radix Rhodiolae, Radix Angelicae Sinensis, Pseudobulbus Cremastrae Seu Pleiones, Herba Scutellariae Barbatae, Rhizoma Chuanxiong, Caulis Spatholobi, and the Semen Coicis bound up with gauze decocts 20 minutes, finally add Flos Chrysanthemi Indici, Flos Sophorae, Radix Glycyrrhizae decocts 10 minutes, filter, obtain filtrate, merge twice filtrate, for subsequent use, step 2: by weight proportion of the present invention, take Radix Ginseng, Ganoderma puts into marmite, adds the water of 3-4 centimetre, with slow fire boiling 50 minutes, filters, obtains filtrate, for subsequent use, step 3: by weight proportion of the present invention, takes Rhizoma Paridis and puts into marmite, adds the water of 3 cm, decocts 30 minutes, filters, obtains filtrate, for subsequent use, step 4: by weight proportion of the present invention, takes Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba (parched), Radix Rehmanniae Preparata pulverizing, is ground to 120 mesh sieves, for subsequent use, step 5: by the medicinal liquid mixing in step one, step 2, step 3 together, then add the medicated powder Homogeneous phase mixing of step 4, both the Chinese medicine decoction of alleviation poorly differentiated adenocarcinoma cancer of the present invention.