CN104857216A - Pharmaceutical preparation for treating duodenal ulcer - Google Patents
Pharmaceutical preparation for treating duodenal ulcer Download PDFInfo
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- CN104857216A CN104857216A CN201510304925.XA CN201510304925A CN104857216A CN 104857216 A CN104857216 A CN 104857216A CN 201510304925 A CN201510304925 A CN 201510304925A CN 104857216 A CN104857216 A CN 104857216A
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- duodenal ulcer
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Abstract
The invention belongs to the field of medicine, and specifically provides a pharmaceutical preparation for treating duodenal ulcer. The pharmaceutical preparation is prepared from the following raw materials in parts by weight: 20 parts of botrychium lanuginosum, 15 parts of herba pteridis multifidae, 10 parts of codonopsis pilosula, 18 parts of radix astragali, 9 parts of rhizoma atractylodis, 10 parts of rhizoma pinelliae, 6 parts of radix bupleuri, 10 parts of fructus aurantii immaturus, 12 parts of radix paeoniae alba, 18 parts of herba violae, 9 parts of flos chrysanthemi indici, 5 parts of radix aucklandiae, 6 parts of radix angelicae dahuricae, 50 parts of fructus trichosanthis, 9 parts of rheum officinale, 15 parts of semen cannabidis and 3 parts of radix glycyrrhizae. According to the invention, the pharmaceutical preparation can be used for treating duodenal ulcer.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of pharmaceutical preparation and the preparation method and application that treat duodenal ulcer.
Background technology
Duodenal ulcer is one of commonly encountered diseases in population of China, frequently-occurring disease, is the common type of peptic ulcer.Be apt to occur in the winter and spring that climate change is larger.Male's sickness rate is apparently higher than women.Abnormal with gastric acid secretion, helicobacter pylori (H.pylori) infects, NSAID (non-steroidal anti-inflammatory drug) (NSAID), live and diet is irregular, work and ambient pressure, smoking, drink and psychologic factors closely related.Duodenal ulcer mostly occurs at pyloric cap (95%), in the majority with antetheca, is secondly rear wall, lower wall, upper wall.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of pharmaceutical preparation and the preparation method and application that treat duodenal ulcer.
Technical scheme: the object of the invention is by following scheme realize:
Treat a pharmaceutical preparation for duodenal ulcer, it is prepared by the raw material of following parts by weight: solely Herba pteridii latiusculi beanstalk 20 parts, Herba Pteridis Multifidae 15 parts, Radix Codonopsis 10 parts, the Radix Astragali 18 parts, Rhizoma Atractylodis 9 parts, the Rhizoma Pinelliae 10 parts, Radix Bupleuri 6 parts, Fructus Aurantii Immaturus 10 parts, the Radix Paeoniae Alba 12 parts, Herba Violae 18 parts, Flos Chrysanthemi Indici 9 parts, the Radix Aucklandiae 5 parts, the Radix Angelicae Dahuricae 6 parts, Fructus Trichosanthis 50 parts, Radix Et Rhizoma Rhei 9 parts, pockmarks core 15 parts, 3 parts, Radix Glycyrrhizae.
The application of pharmaceutical preparation in the medicine of preparation treatment duodenal ulcer of described treatment duodenal ulcer.
In the present invention, only Herba pteridii latiusculi beanstalk is fern Botrychiaceae Herba pteridii latiusculi beanstalk platymiscium only Herba pteridii latiusculi beanstalk Botrychium lanuginosum Wall., with all herbal medicine, and heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For lung abscess, eye conjunctivitis; Traumatic injury is controlled in external, venom, lymphoid tuberculosis.
Herba Pteridis Multifidae is a kind of pteridophyta, belongs to Pteridaceae, Pteris.Formal name used at school Pteris multifda poir.Happiness growth is at concealment, moistening, warm place.Also drought-enduring, in southern winter, the plant arid in warp-February grown in crack of stone, still unlikely completely withered.The main product Yangtze river basin and on the south each province, district, the north Shaanxi, Hebei, Shandong etc. economize also have distribution.Tonifying blood and regulating menstruation, yin nourishing.For menoxenia, deficiency of YIN hectic fever, has a dizzy spell, women's asthenia.The present invention is with all herbal medicine.All the other medicines all meet standards of pharmacopoeia or are documented in Chinese medicine voluminous dictionary.
Beneficial effect: the only Herba pteridii latiusculi beanstalk of the present invention, Herba Pteridis Multifidae, Radix Codonopsis, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Pinelliae, Radix Bupleuri, Fructus Aurantii Immaturus, the Radix Paeoniae Alba, Herba Violae, Flos Chrysanthemi Indici, the Radix Aucklandiae, the Radix Angelicae Dahuricae, Fructus Trichosanthis, Radix Et Rhizoma Rhei, pockmarks core, Radix Glycyrrhizae, obtained medicine can safe and effective treatment duodenal ulcer.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1. prepare embodiment
1.1 take only Herba pteridii latiusculi beanstalk 20g, Herba Pteridis Multifidae 15g, Radix Codonopsis 10g, Radix Astragali 18g, Rhizoma Atractylodis 9g, Rhizoma Pinelliae 10g, Radix Bupleuri 6g, Fructus Aurantii Immaturus 10g, Radix Paeoniae Alba 12g, Herba Violae 18g, Flos Chrysanthemi Indici 9g, Radix Aucklandiae 5g, Radix Angelicae Dahuricae 6g, Fructus Trichosanthis 50g, Radix Et Rhizoma Rhei 9g, pockmarks core 15g, Radix Glycyrrhizae 3g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of duodenal ulcer.Oral, every bu is taken for twice sooner or later.
1.2 take only Herba pteridii latiusculi beanstalk 20g, Herba Pteridis Multifidae 15g, Radix Codonopsis 10g, Radix Astragali 18g, Rhizoma Atractylodis 9g, Rhizoma Pinelliae 10g, Radix Bupleuri 6g, Fructus Aurantii Immaturus 10g, Radix Paeoniae Alba 12g, Herba Violae 18g, Flos Chrysanthemi Indici 9g, Radix Aucklandiae 5g, Radix Angelicae Dahuricae 6g, Fructus Trichosanthis 50g, Radix Et Rhizoma Rhei 9g, pockmarks core 15g, Radix Glycyrrhizae 3g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of duodenal ulcer.Oral, every bu is taken for twice sooner or later.
1.3 take only Herba pteridii latiusculi beanstalk 20g, Herba Pteridis Multifidae 15g, Radix Codonopsis 10g, Radix Astragali 18g, Rhizoma Atractylodis 9g, Rhizoma Pinelliae 10g, Radix Bupleuri 6g, Fructus Aurantii Immaturus 10g, Radix Paeoniae Alba 12g, Herba Violae 18g, Flos Chrysanthemi Indici 9g, Radix Aucklandiae 5g, Radix Angelicae Dahuricae 6g, Fructus Trichosanthis 50g, Radix Et Rhizoma Rhei 9g, pockmarks core 15g, Radix Glycyrrhizae 3g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of duodenal ulcer.Oral, every bu is taken for twice sooner or later.
2. the present invention is to the clinical research of duodenal ulcer
2.1 physical data: inventor collects the out-patient of 50 routine duodenal ulcers altogether between in July ,-2014 in January, 2013, age 32-65 year, course of disease 0.5-2.Be divided at random: treatment group 25 example, blank group 25 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2.2 diagnostic criterias: through gastroscopy, are diagnosed as duodenal ulcer, and the indistinct pain in visible gastral cavilty portion, meet cold or increase the weight of on an empty stomach, liking warm pain relieved by pressing, alleviate after food, vomiting watery fluid, in tired or outbreak or increase the weight of, mental weariness after suffering from cold, extremity are not warm, large loose stool, pale tongue with white fur, thready and weak pulse, all gets rid of and has the diseases such as hepatic and kidney function obstacle, hypertension, diabetes.
2.3 test method
2.3.1 the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1.1, sooner or later each once.30 days courses for the treatment of.
2.3.2 blank group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
2.4 criterions of therapeutical effect and therapeutic outcome
2.4.1 criterion of therapeutical effect
Recovery from illness: after treatment, clinical symptoms, sign disappear, stomach Microscopic observation, and prompting ulcer healing enters cicatricial phase; Effective: after treatment, Upper abdominal pain disappears, but still has the situation of belch, acid regurgitation, but occurrence frequency obviously reduces, stomach Microscopic observation, and prompting ulcer disappears, and still has inflammation around; Effective: clinical symptoms, sign make moderate progress, stomach Microscopic observation, prompting ulcer area reduces and is less than 50%, or ulcer number reduces; Invalid: after treatment, clinical symptoms and sign are not improved, and even worsen, and after gastroscope check, ulcer surface is unchanged.
2.4.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 25 | 5 | 11 | 6 | 3 | 88 |
| Blank group | 25 | 1 | 1 | 0 | 23 | 8 |
Visible, the medicine that the present invention obtains can safe and effective treatment duodenal ulcer.
Claims (2)
1. treat the pharmaceutical preparation of duodenal ulcer for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: solely Herba pteridii latiusculi beanstalk 20 parts, Herba Pteridis Multifidae 15 parts, Radix Codonopsis 10 parts, the Radix Astragali 18 parts, Rhizoma Atractylodis 9 parts, the Rhizoma Pinelliae 10 parts, Radix Bupleuri 6 parts, Fructus Aurantii Immaturus 10 parts, the Radix Paeoniae Alba 12 parts, Herba Violae 18 parts, Flos Chrysanthemi Indici 9 parts, the Radix Aucklandiae 5 parts, the Radix Angelicae Dahuricae 6 parts, Fructus Trichosanthis 50 parts, Radix Et Rhizoma Rhei 9 parts, pockmarks core 15 parts, 3 parts, Radix Glycyrrhizae.
2. treat the application of pharmaceutical preparation in the medicine for the treatment of duodenal ulcer of duodenal ulcer as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510304925.XA CN104857216A (en) | 2015-06-05 | 2015-06-05 | Pharmaceutical preparation for treating duodenal ulcer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510304925.XA CN104857216A (en) | 2015-06-05 | 2015-06-05 | Pharmaceutical preparation for treating duodenal ulcer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104857216A true CN104857216A (en) | 2015-08-26 |
Family
ID=53903681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510304925.XA Withdrawn CN104857216A (en) | 2015-06-05 | 2015-06-05 | Pharmaceutical preparation for treating duodenal ulcer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104857216A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642539A (en) * | 2009-09-01 | 2010-02-10 | 廖国新 | Medicine composition for treating peptic ulcer and preparation method thereof |
-
2015
- 2015-06-05 CN CN201510304925.XA patent/CN104857216A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642539A (en) * | 2009-09-01 | 2010-02-10 | 廖国新 | Medicine composition for treating peptic ulcer and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 蓝娇娜等: "消化性溃疡的中医药治疗概述", 《甘肃中医》 * |
| 陈慈煦: "胃与十二指肠溃疡病诊治体会", 《贵阳中医学院学报》 * |
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| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
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Application publication date: 20150826 |