CN104856913A - Anti-aging lotion and preparation method thereof - Google Patents
Anti-aging lotion and preparation method thereof Download PDFInfo
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- CN104856913A CN104856913A CN201510348947.6A CN201510348947A CN104856913A CN 104856913 A CN104856913 A CN 104856913A CN 201510348947 A CN201510348947 A CN 201510348947A CN 104856913 A CN104856913 A CN 104856913A
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- astringent
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Abstract
The invention relates to an anti-aging lotion and a preparation method thereof. The anti-aging lotion comprises the following components in percentage by weight: 2-9% anti-wrinkle peptide, 1.5-6.5% of vitamin E, 10-28% of a geranium extract, 1.5-5.5% of polysorbate, 0.05-1% of methylparaben, 0.05-0.8% of propylparaben, 0.5-1.2% of monoglyceride, 0.5-1.2% of sodium lauryl sarcosine, 2-9% of ethanol and the balance of water. The invention further relates to the preparation method for the anti-aging lotion. The anti-aging lotion has the benefits that various anti-aging active ingredients are matched and mixed, so that effective components can penetrate deep cell centers of skin; the compatibility of all of the components has a synergistic effect, so that the anti-free radical, anti-aging, moisturizing effects are realized together.
Description
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of defying age astringent and preparation method thereof.
Background technology
Along with the development of society, the environment around people goes from bad to worse, and the sharp increase of operating pressure and life stress people are had increasing bad life habits, all poses a big pressure to skin.Ultraviolet, air pollution, very large to the injury of skin, collagen protein is caused to run off, the loss gradually of the Moisture factor such as collagen protein, skin tissue cell and intercellular moisture reduce, and cause cell arrangement tight, support collagen peptide bond and the elasticated net fracture of skin, its spiral net-shaped structure is destroyed immediately, skin histology is oxidized, atrophy, subside, and skin just there will be drying, wrinkle, the aging phenomenon such as lax nonelastic, to cause before aging extremely.Thus the problem of skin aging that faces of human body, more serious than ever.
Astringent is the conventional material of skin basic nursing conventional at present, and routine use is frequent, thus considers in astringent, add certain activity of fighting against senium material thus reaches antidotal effect when routine use basis skin-protection product.At present about the existing a lot of report of research of antidotal astringent, Chinese patent CN101721340A discloses a kind of cosmetic composition for delaying skin aging, main component is Olibanum extract or oat extract or both mixture, auxiliary element is Matrixyl and carnosine, under the prerequisite of the normal physiological metabolism and function that can safeguard skin, utilize various composition reasonable combination, coordinate share, reached effect of delaying skin aging by the number of ways effect of component.Chinese patent CN101966135A discloses a kind of astringent containing nanometer skin moistening composition, comprises: surfactant 0.1% ~ 20%, polyhydric alcohol 0.1% ~ 30%, emollient 0.1% ~ 20%, wetting agent 0.1% ~ 30%, antiseptic 0.001 ~ 3%, other additive 0.01% ~ 15% and water 50 ~ 98%.This astringent can make up common astringent cannot the deficiency of effective skin moistening, can realize again common milky lotion, emollient cream cannot the shortcoming of moisturizing rapidly.Chinese patent CN101234132A discloses the purposes that a kind of Radix Angelicae Sinensis or its extract prepare skin care item, Radix Angelicae Sinensis or its extract have regulation of skin secretory function, moisture-keeping functions, prophylactic treatment mottle, promote that skin newly becomes the effect of metabolism, with Radix Angelicae Sinensis or its extract for the main active in skin care item, for improving the colour of skin and the health status of skin.
Whether it is single that current astringent used is suitable for crowd, a kind of product can be had can to have the ability of the rapid moisturizing of astringent, be applicable to dryness, adult form skin, and antidotal effect can be had again to become the target of those skilled in the art exploration of row.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of defying age astringent and preparation method thereof, there is the ability of the rapid moisturizing of astringent, be applicable to dryness, adult form skin, antidotal effect can be had again, and anti-aging effects being good.
The technical solution adopted in the present invention is: a kind of defying age astringent, consists of the following composition by weight percentage: wrinkle removal peptide 2-9%, vitamin E 1.5-6.5%, Flos Pelargonii Hortori 10-28%, polysorbate 1.5-5.5%, methyl hydroxybenzoate 0.05-1%, propylparaben 0.05-0.8%, monoglyceride 0.5-1.2%, sodium lauroyl sarcosine 0.5-1.2%, ethanol 2-9%, surplus are water.
Preferably consist of the following composition by weight percentage in above-mentioned defying age astringent: wrinkle removal peptide 5%, vitamin E 4.5%, Flos Pelargonii Hortori 18%, polysorbate 3.5%, methyl hydroxybenzoate 0.55%, propylparaben 0.6%, monoglyceride 0.8%, sodium lauroyl sarcosine 0.8%, ethanol 7%, surplus are water.
Present invention also offers the preparation method of above-mentioned defying age astringent, (1) wrinkle removal peptide, vitamin E and sodium lauroyl sarcosine fully dissolve in water, vacuum within 30 minutes, is kept slowly to stir at 75 DEG C of constant temperature, mixing speed 30 revs/min, obtained aqueous phase; (2) Flos Pelargonii floral leaf is added water carry out microwave extraction, 550W ~ 600W microwave extraction 3min ~ 4min, stop, again at 550W ~ 600W microwave extraction 4min ~ 5min after the 1min ~ 2min of interval, stopping; Repeat to extract, stop step, make total extraction time be no less than 15min, obtain Flos Pelargonii Hortori; (3) Flos Pelargonii Hortori is added aqueous phase, cool after homogenizing, add polysorbate, methyl hydroxybenzoate, propylparaben, monoglyceride, ethanol mix homogeneously, obtained anti-ageing wrinkle removal astringent.
Described astringent specification is 100ml, 200ml, 300ml.
Present invention also offers the application of a kind of described defying age astringent as anti-aging cosmetics, be particularly suitable for dryness, adult form skin.
In the present invention, the Main Function of each active component is as follows:
Wrinkle removal peptide: formal name used at school is again acetylation six peptide, class creotoxin composition, it has the function of creotoxin, but does not have the toxicity of creotoxin.Block myoneural transmission speed, thus suppress the generation polypeptide of expression stricture of vagina and fine wrinkles usually by the compound of 10-100 amino acid molecular dehydrating condensation.Polypeptide is the physiological regulator that body weight for humans is wanted, and it can regulate human body physiological function comprehensively, effectively resists aging.
Vitamin E: speckle removing, acne removing print effect.Natural Vitamin E is easy to be absorbed by the skin, and can promote the metabolic function of skin, prevent pigmentation, effectively the formation of prevention senile plaque.It is one of studied and that application is maximum anti-ageing composition, belongs to the lipid fractions that human body is main, can remove the generation that interior free yl reacts with blocking oxide, and alleviate and repair cell membrane damage, reach to antidotal effect.Due to the vitamin E only containing minute quantity in cell, and human body self cannot synthesize, so can only obtain from external fill-in, unpurified vegetable oil, Semen Armeniacae Amarum, nut wet goods all contain more vitamin E.
Flos Pelargonii Hortori: Flos Pelargonii is applicable to various skin, because it can balance sebum secretion and make turgor.May to eczema, burn, herpes zoster, herpes, tinea and chilblain be useful.Slack and undisciplined, pore is blocked and oily skin also fine, can be rated as a kind of comprehensive clean skin oil.Due to Flos Pelargonii energy blood circulation promoting, after using, can allow pale skin is comparatively ruddy vigor.Described Flos Pelargonii Hortori is: adopt the product that water or steam distillation or machining Flos Pelargonii floral leaf get.
Beneficial effect of the present invention is: the present invention can inject powerful moisturizing composition for skin, moisturizing composition, aging ingredient is allowed directly to ooze skin bottom, supplement nutrient to skin, reduce wrinkle, strengthen skin defensive enginery, stop collagen protein loss and other dry skin problems repeatedly to occur.In the present invention, multiple activity of fighting against senium composition collocation is adjusted, and make effective ingredient go deep into skin deep layer cells center, above compatibility has synergism, jointly plays the effect of free radical resisting, defying age, moisturizing.The new formula that the present invention proposes is simple and remarkable, the gentle zest of anti-aging effects is little, easily produces, and application is convenient, effective, has definite effect, has no side effect, the feature that cost is low.
Detailed description of the invention
In the present invention, if not refer in particular to, all parts, percentage ratio are weight or volume unit, and all equipment and raw material etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
Embodiment 1: treatment defying age astringent, be water containing wrinkle removal peptide 5%, vitamin E 4.5%, Flos Pelargonii Hortori 18%, polysorbate 3.5%, methyl hydroxybenzoate 0.55%, propylparaben 0.6%, monoglyceride 0.8%, sodium lauroyl sarcosine 0.8%, ethanol 7%, surplus, be prepared into 100ml astringent.
Embodiment 2: treatment defying age astringent, be water containing wrinkle removal peptide 5%, vitamin E 4.5%, Flos Pelargonii Hortori 18%, polysorbate 3.5%, methyl hydroxybenzoate 0.55%, propylparaben 0.6%, monoglyceride 0.8%, sodium lauroyl sarcosine 0.8%, ethanol 7%, surplus, be prepared into 200ml astringent.
Comparative example 1: by the wrinkle removal peptide water consumption substitution in embodiment 1, all the other operations, with embodiment 1, obtain astringent.
Comparative example 2: by the vitamin E water consumption substitution in embodiment 1, all the other operations, with embodiment 1, obtain astringent.
Comparative example 3: by the Flos Pelargonii Hortori water consumption substitution in embodiment 1, save Flos Pelargonii extraction step, all the other operations, with embodiment 1, obtain astringent.
The preparation method of described embodiment 1 defying age astringent is: (1) wrinkle removal peptide, vitamin E and sodium lauroyl sarcosine fully dissolve in water, vacuum within 30 minutes, is kept slowly to stir at 75 DEG C of constant temperature, mixing speed 30 revs/min, obtained aqueous phase; (2) Flos Pelargonii floral leaf is added water carry out microwave extraction, 550W ~ 600W microwave extraction 3min ~ 4min, stop, again at 550W ~ 600W microwave extraction 4min ~ 5min after the 1min ~ 2min of interval, stopping; Repeat to extract, stop step, make total extraction time be no less than 15min, obtain Flos Pelargonii Hortori; (3) Flos Pelargonii Hortori is added aqueous phase, cool after homogenizing, add polysorbate, methyl hydroxybenzoate, propylparaben, monoglyceride, ethanol mix homogeneously, obtained anti-ageing wrinkle removal astringent.Take a morsel astringent in the palm of the hand after clean of morning and evening every day, claps gently and absorb to abundant with Finger Taps after face, every day twice, each 1-2ml.
Experimental example 1, antiradical activities measure
The astringent adopting the embodiment of the present invention 1, comparative example 1 ~ 3 to prepare is that example carries out anti-DPPH free radical ability mensuration.First, accurately take 20mg DPPH (1,1-dimethyl benzyl phenylhydrazine), be surely dissolved in 250mL volumetric flask with dehydrated alcohol, DPPH concentration is 2 × 10
-4mol/L.Abundant mixing, after room temperature dark leaves standstill 30min, measures absorbance under 517nm wavelength.Same mensuration repetition 3 times.Experimental measuring and DPPH clearance rate the results are shown in Table 1.
DPPH free radical scavenging activity (%)=[(1-A sample-A is blank)/A contrasts] × 100%
A sample: the absorbance of sample under 517nm wavelength.
A is blank: blank absorbance under 517nm wavelength.
A contrasts: to the absorbance impinged upon under 517nm wavelength.
Table 1
| Group | DPPHml | Sample ml | Water ml | DPPH clearance rate % |
| Embodiment 1 | 2.0 | 2.0 | 0 | 94.6 |
| Comparative example 1 | 2.0 | 2.0 | 0 | 61.2 |
| Comparative example 2 | 2.0 | 2.0 | 0 | 58.3 |
| Comparative example 3 | 2.0 | 2.0 | 0 | 65.5 |
| Contrast | 2.0 | 0 | 2.0 | 0 |
Table 1 experimental result shows, the antiradical activities of astringent prepared by comparative example 1 ~ 3 is starkly lower than the embodiment of the present invention 1 product, has good synergistic function between the component showing product of the present invention.
Experimental example 2, defying age ability measure
The astringent adopting the embodiment of the present invention 1, comparative example 1 ~ 3 to prepare is example, with SOD vigor for index carries out defying age ability mensuration.
Kunming kind cleaning grade mice 50, male and female half and half, body weight (20 ± 2) g, is provided by Zhejiang University's Experimental Animal Center, is divided at random 5 groups (matched group, sample sets), often organizes 10.From first day 8:00 in morning, the astringent that every day prepares to the sample sets gavage embodiment of the present invention 1, comparative example 1-3 carries out Experiment intervention, and every 1 day mouse weights 1 time, gavage amount (10g/kg) is adjusted accordingly according to body weight.The normal saline of matched group also gavage equivalent.Sacrificed by decapitation after continuous 1 month, gets brain cold saline and rinses, strip cerebral cortex for subsequent use.
Table 2
| Group | SOD vigor U/ml |
| Embodiment 1 | 230.2±19.1 |
| Comparative example 1 | 176.1±15.5 |
| Comparative example 2 | 168.3±17.4 |
| Comparative example 3 | 180.5±12.7 |
| Contrast | 150.2±15.1 |
Table 2 experimental result shows, astringent prepared by the present invention can significantly improve the SOD vigor of mouse brain cortex, active by the SOD improving cortex, enhance the ability of body scavenging free radicals, alleviate the macromolecular attack of radical pair biomembrane, thus weaken the infringement of too much radical pair biomembrane, ensure that the complete of membrane structure and function, delayed apoptotic generation, astringent prepared by display the present invention has excellent anti-aging effects.The antiradical activities of astringent prepared by comparative example 1 ~ 3 is starkly lower than the embodiment of the present invention 1 product, has good synergistic function between the component showing product of the present invention.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.
Claims (7)
1. a defying age astringent, it is characterized in that, comprise following component by weight percentage: wrinkle removal peptide 2-9%, vitamin E 1.5-6.5%, Flos Pelargonii Hortori 10-28%, polysorbate 1.5-5.5%, methyl hydroxybenzoate 0.05-1%, propylparaben 0.05-0.8%, monoglyceride 0.5-1.2%, sodium lauroyl sarcosine 0.5-1.2%, ethanol 2-9%, surplus are water.
2. a kind of defying age astringent according to claim 1, it is characterized in that, comprise the component of following weight portion: wrinkle removal peptide 5%, vitamin E 4.5%, Flos Pelargonii Hortori 18%, polysorbate 3.5%, methyl hydroxybenzoate 0.55%, propylparaben 0.6%, monoglyceride 0.8%, sodium lauroyl sarcosine 0.8%, ethanol 7%, surplus are water.
3. a kind of defying age astringent according to claim 1, it is characterized in that, comprise the component of following weight portion: wrinkle removal peptide 2%, vitamin E 1.5%, Flos Pelargonii Hortori 10%, polysorbate 1.5%, methyl hydroxybenzoate 0.05%, propylparaben 0.8%, monoglyceride 0.5%, sodium lauroyl sarcosine 0.5%, ethanol 9%, surplus are water.
4. a kind of defying age astringent according to claim 1, it is characterized in that, comprise the component of following weight portion: wrinkle removal peptide 9%, vitamin E 6.5%, Flos Pelargonii Hortori 10%, polysorbate 5.5%, methyl hydroxybenzoate 01%, propylparaben 0.8%, monoglyceride 1.2%, sodium lauroyl sarcosine 0.5%, ethanol 9%, surplus are water.
5. the preparation method of the described defying age astringent of one of claim 1-4, it is characterized in that, comprise the following steps: (1) wrinkle removal peptide, vitamin E and sodium lauroyl sarcosine fully dissolve in water, vacuum within 30 minutes, is kept slowly to stir at 75 DEG C of constant temperature, mixing speed 30 revs/min, obtained aqueous phase;
(2) Flos Pelargonii floral leaf is added water carry out microwave extraction, 550W ~ 600W microwave extraction 3min ~ 4min, stop, again at 550W ~ 600W microwave extraction 4min ~ 5min after the 1min ~ 2min of interval, stopping; Repeat to extract, stop step, make total extraction time be no less than 15min, obtain Flos Pelargonii Hortori;
(3) Flos Pelargonii Hortori is added aqueous phase, cool after homogenizing, add polysorbate, methyl hydroxybenzoate, propylparaben, monoglyceride, ethanol mix homogeneously, obtained anti-ageing wrinkle removal astringent.
6. a kind of defying age astringent according to claim 5, is characterized in that, described astringent specification is 100ml, 200ml, 300ml.
7. described in any one of claim 1-4, defying age astringent, as an application for anti-aging cosmetics, is characterized in that, this astringent is suitable for dryness, adult form skin.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107693425A (en) * | 2017-10-31 | 2018-02-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of antibacterial skin care compositions and application |
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| CN103816104A (en) * | 2014-02-26 | 2014-05-28 | 南通恒隆化工有限公司 | Anti-wrinkle moisturizing lotion |
| CN104042502A (en) * | 2014-06-10 | 2014-09-17 | 刘佰岭 | Deeply permeating absorbed skin care composition capable of promoting metabolism and delaying senescence |
| CN104352418A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Anti-ageing essence |
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Patent Citations (5)
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| CN101450027A (en) * | 2007-12-07 | 2009-06-10 | 南京莱因医药科技有限公司 | Preparation method of wrinkle-removal cosmetic face cream, face mask and latex |
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| CN104042502A (en) * | 2014-06-10 | 2014-09-17 | 刘佰岭 | Deeply permeating absorbed skin care composition capable of promoting metabolism and delaying senescence |
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| CN107693425A (en) * | 2017-10-31 | 2018-02-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of antibacterial skin care compositions and application |
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