CN104855398B - The purposes and acaricide of Sitosterolum linoleate - Google Patents
The purposes and acaricide of Sitosterolum linoleate Download PDFInfo
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- CN104855398B CN104855398B CN201510158336.5A CN201510158336A CN104855398B CN 104855398 B CN104855398 B CN 104855398B CN 201510158336 A CN201510158336 A CN 201510158336A CN 104855398 B CN104855398 B CN 104855398B
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- linoleate
- cupreol
- acaricide
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Abstract
The present invention provides the purposes and acaricide of a kind of Sitosterolum linoleate, the acaricide is made up of Sitosterolum linoleate and customary adjuvant, the quality of wherein Sitosterolum linoleate accounts for 0.05% the 99% of Sitosterolum linoleate acaricide quality, and customary adjuvant accounts for 1% 99.95%.The invention provides a kind of new harmonious acaricide to person poultry safety, environmentally friendly, the comprehensive regulation to ecological environmental protection, human health and disease all has far-reaching significance.
Description
Technical field
The present invention relates to a kind of technical field of pesticide, specifically, be related to a kind of cupreol linoleate purposes and β-
Sitosterol linoleate ester acaricide.
Background technology
Phytophagous mites is found on the crops all over the world, it has, and small volume, breeding be fast, strong adaptability with
And the features such as be also easy to produce the resistance to the action of a drug, be it is generally acknowledged be difficult preventing and treating pest communities.It is used on the pesticide market of China at present
The most dependence on import of acaricide, the acaricidal expense of import accounts for the 88.8% of general import agricultural chemicals expense.And mite class is to crop
The loss caused, has obvious increase in Past 30 Years.Main cause is intensive monoculture and killed using non-specific
Worm agent.Secondly because the growth time of one generation of mite class is shorter, resistance can be produced to original acaricide rapidly.These desinsections
Often acaricidal activity is not high for agent, and mite class natural enemy has also been eliminated while mite class is killed.At present, the 3R problems of chemical pesticide are
Residual (Residue), resistance (Resistance) and pest resurgence (Resurgence) are generally paid close attention to by people, the mankind
Understanding to agricultural chemicals is also more and more deep, and the use of agricultural chemicals is not focused on killing off the insect pests, but more focuses on regulation.Therefore, use
Obligate acaricide turns into the major measure of preventing and treating phytophagous mites, and acaricidal development is inevitable towards efficient, wide spectrum, low toxicity, peace
Full biological pesticide and insect hormone type agricultural chemicals direction develops, and meets the demand in market.
Cupreol linoleate (β-sitosterol linoleate), pale yellow oil, molecular formula：C47H8002,
Molecular weight：676, it is a kind of important phytosterin ester, can be obtained by cupreol and linoleic acid through esterification, as can such as uses
Organic phase enzymatic catalysis esterification, can also obtain through refining from plant and obtain, as such as the river radix paeoniae rubrathe, peel of cape jasmine fruit etc..It can not only change
The oil-soluble of kind sterol, it is convenient to be applied in food processing, also have the biology of cupreol and linoleic acid two kinds of active components concurrently
Function is learned, and it is existing studies have reported that it has very strong anti-oxidant and bactericidal action.
Found through being retrieved to existing technical literature, cupreol linoleate answering in acaricide is prepared is there is no at present
With report；A kind of current also no and environment compatibility is good, harmonious acaricide to mammalian safe.
The content of the invention
The present invention for deficiencies of the prior art there is provided it is a kind of efficiently, noresidue, production cost be low, economy
Practical, environment-friendly, high comprehensive performance a kind of cupreol linoleate acaricide and its preparation and new application.
The present invention seeks to what is be achieved through the following technical solutions：
The present invention provides a kind of purposes of cupreol linoleate, i.e., kill cupreol linoleate applied to preparation
Mite agent.
Preferably, the mite can be Tetranychus cinnabarinus, the plant evil mite such as Tetranychus urticae.
The present invention provides a kind of cupreol linoleate acaricide, and the acaricide is by cupreol linoleate
(i.e. bulk drug) is constituted with customary adjuvant.The quality of wherein cupreol linoleate accounts for cupreol linoleate acaricide matter
The 0.05%-99% of amount, customary adjuvant accounts for the 1%-99.95% of cupreol linoleate acaricide quality.
Preferably, the customary adjuvant is solubilizer, synergist, emulsifying agent, bleeding agent etc. one or more.
Preferably, the solubilizer is neopelex, Potassium dodecylbenzenesulfonate, polysorbate, poly- second two
One or more during alcohol, sorbierite polyoxy ether, lignosulfonates, tea seed cake, Chinese honey locust (fruit) etc. are all.
Preferably, the emulsifying agent is spans, Tweens, ethylene glycol esters, propane diols esters and/or polyethylene glycol type
It is one or more in nonionic surfactant etc..
Preferably, the synergist is one or more in Tea Saponin, APEO etc..
Preferably, the bleeding agent is azone etc..
Weigh certain cupreol linoleate solvent to dissolve, selection adds various auxiliary materials, as such as, solubilizer, increasing
Agent, emulsifying agent, bleeding agent etc. are imitated, according to various techniques, various forms of acaricides are made, for example：Pulvis, missible oil, suspension
Agent, dry suspending agent, emulsifiable concentrate, sustained release agent, aqueous emulsion, spray etc..Wherein, solvent can be water, ethanol, methanol, acetone, ring
One or more in all organic solvents such as hexanone, petroleum ether, petroleum aromatic, purified petroleum benzin, ethyl acetate, toluene, dimethylbenzene.
The above-mentioned acaricidal application of cupreol linoleate of the present invention, be specially：Added water under stirring at normal temperature
In cupreol linoleate acaricide, it is set to be diluted to the concentration that cupreol linoleate i.e. bulk drug accounts for 0.5-40wt%
After be spray applied.
Compared with prior art, the invention has the advantages that：
The invention provides a kind of new harmonious acaricide to person poultry safety, environmentally friendly, to ecological environmental protection,
The comprehensive regulation of human health and disease all has far-reaching significance.Compared with traditional agricultural chemicals, the present invention has following spy
Point and advantage：
(1) cupreol linoleate is a kind of natural products, with nontoxic, the features such as degradable, for people, animal and life
State environment be it is friendly, it is safe；
(2) cupreol linoleate source is easy, it is possible to use esterification is synthesized, and can also directly be carried from plant
Take, method is simple and easy to apply, large-scale industrial production can be carried out；
(3) present invention is to find that cupreol linoleate has mite killing bioactivity first, and is configured to first
Acaricide.Through experiment, to Tetranychus cinnabarinus preventive effect up to 95.3%.
Embodiment
With reference to specific embodiment, the present invention is described in detail.Following examples will be helpful to the technology of this area
Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that to the ordinary skill of this area
For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention
Protection domain.
Embodiment 1
Cupreol linoleate 2.5g is weighed, is dissolved with 20g ethanol solutions, 5g Tween-80s, dissolving, according to normal is added
Rule technique, is made cupreol linoleate acaricide of the present invention, then in made cupreol linoleate acaricide
It is diluted with water, the concentration for making cupreol linoleate, i.e. bulk drug is 1%.Finally, by the cupreol linoleic acid after dilution
Ester acaricide carries out indoor biological determination of activity to Tetranychus cinnabarinus, and method is surveyed in SOP according to national southern pesticides discovery center life
Tetranychid leaching stem infusion process carry out.The life or death borer population of each processing is investigated after 24 hours, its preventive effect is 77.8%.
Embodiment 2
Cupreol linoleate 38g is weighed, is dissolved with 12g ethyl acetate, the 25g such as emulsifying agent are added wherein, according to
Common process, is made cupreol linoleate acaricide of the present invention, then in made cupreol linoleate acaricide
In be diluted with water, make cupreol linoleate, i.e. bulk drug concentration be 24%.Finally, it is the cupreol after dilution is sub-
Oleate acaricide carries out indoor biological determination of activity to Tetranychus cinnabarinus, and method is surveyed according to national southern pesticides discovery center life
Tetranychid leaching stem infusion process in SOP is carried out.The life or death borer population of each processing is investigated after 24 hours, its preventive effect is 93.8%.
Embodiment 3
Cupreol linoleate 80g is weighed, is dissolved with 10g ethanol, the grade 10g of emulsifier span -20 is added wherein, is pressed
More solito technique, is made cupreol linoleate acaricide of the present invention, then in made β-sitosterol linoleate ester mite killing
It is diluted with water in agent, it is 37% to make the cupreol linoleate i.e. concentration of bulk drug.Finally, it is the cupreol after dilution is sub-
Oleate acaricide carries out giving birth to survey to Tetranychus cinnabarinus using indoor pot method, counts the death rate after 24 hours, its preventive effect is
98.6%.
Embodiment 4
Cupreol linoleate 200g is weighed, is dissolved with 550g methanol, emulsifier tween -245, department are added wherein
The grade 250g of disk -20, according to common process, is made cupreol linoleate acaricide of the present invention, then in made β-paddy steroid
It is diluted with water in alcohol linoleate acaricide, it is 7% to make the cupreol linoleate i.e. concentration of bulk drug.Finally, it will dilute
Cupreol linoleate acaricide afterwards carries out giving birth to survey to Tetranychus cinnabarinus using indoor pot method, counts dead after 24 hours
Rate, its preventive effect is 95.3%.
Embodiment 5
Cupreol linoleate 500g is weighed, 40g petroleum ether dissolutions are used, emulsifying agent, synergist, solubilising are added wherein
The auxiliary material 15g such as agent, according to common process, is made cupreol linoleate acaricide of the present invention, then in made β-paddy steroid
It is diluted with water in alcohol linoleate acaricide, it is 16% to make the cupreol linoleate i.e. concentration of bulk drug.Finally, it will dilute
Cupreol linoleate acaricide afterwards adopts field plot experiment to Tetranychus cinnabarinus and carries out field control effectiveness test, is united after 48 hours
The death rate is counted, preventive effect reaches 92.3%.
The specific embodiment of the present invention is described above.It is to be appreciated that the invention is not limited in above-mentioned
Particular implementation, those skilled in the art can make various deformations or amendments within the scope of the claims, this not shadow
Ring the substantive content of the present invention.
Claims (8)
1. a kind of purposes of cupreol linoleate, it is characterised in that be applied to cupreol linoleate to prepare mite killing
Agent.
2. the purposes of cupreol linoleate according to claim 1, it is characterised in that the mite be Tetranychus cinnabarinus or
Tetranychus urticae.
3. a kind of cupreol linoleate acaricide, it is characterised in that the acaricide be by cupreol linoleate with
Customary adjuvant is constituted, and the quality of wherein cupreol linoleate accounts for the 0.05%- of cupreol linoleate acaricide quality
99%, customary adjuvant accounts for the 1%-99.95% of cupreol linoleate acaricide quality；The customary adjuvant refers to solubilising
It is one or more in agent, synergist, emulsifying agent, bleeding agent.
4. cupreol linoleate acaricide according to claim 3, it is characterised in that the solubilizer is dodecane
Base benzene sulfonic acid sodium salt, Potassium dodecylbenzenesulfonate, polysorbate, polyethylene glycol, sorbierite polyoxy ether, lignosulfonates, tea
One or more in withered, Chinese honey locust (fruit).
5. cupreol linoleate acaricide according to claim 3, it is characterised in that the emulsifying agent is sapn
One or more in class, Tweens, ethylene glycol esters, propane diols esters and/or polyethylene glycol type nonionic surfactant.
6. cupreol linoleate acaricide according to claim 3, it is characterised in that the synergist is tea soap
One or more in element, APEO.
7. cupreol linoleate acaricide according to claim 3, it is characterised in that the bleeding agent is azone.
8. the acaricidal application of cupreol linoleate described in a kind of any one of claim 3-7, it is characterised in that normal
Added water under temperature stirring in cupreol linoleate acaricide, it is diluted to cupreol linoleate i.e. bulk drug
It is spray applied after the concentration for accounting for 0.5-40wt%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510158336.5A CN104855398B (en) | 2015-04-03 | 2015-04-03 | The purposes and acaricide of Sitosterolum linoleate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510158336.5A CN104855398B (en) | 2015-04-03 | 2015-04-03 | The purposes and acaricide of Sitosterolum linoleate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104855398A CN104855398A (en) | 2015-08-26 |
| CN104855398B true CN104855398B (en) | 2017-08-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510158336.5A Expired - Fee Related CN104855398B (en) | 2015-04-03 | 2015-04-03 | The purposes and acaricide of Sitosterolum linoleate |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109293815A (en) * | 2018-09-18 | 2019-02-01 | 佛山市顺德区巴德富实业有限公司 | A kind of acrylic emulsion and preparation method thereof of anti-dust mite |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1152739C (en) * | 2001-10-26 | 2004-06-09 | 中国科学院新疆理化技术研究所 | Cyclodextrin coated conjugate linoleic acid and its derivative microcapsule |
| CN1200089C (en) * | 2002-02-05 | 2005-05-04 | 中国科学院新疆理化技术研究所 | Health care wine containing conjugaed linoleic acid or conjugated linoleic acid derivant |
| US20050175672A1 (en) * | 2004-02-10 | 2005-08-11 | Kluetz Michael D. | Particulate plant sterol compositions |
| CN101606525A (en) * | 2009-06-26 | 2009-12-23 | 北京农学院 | The new purposes of cupreol |
| CN101731216A (en) * | 2010-01-14 | 2010-06-16 | 北京农学院 | Methyl linoleate acaricide and preparation method therof |
| CN102067834A (en) * | 2010-12-07 | 2011-05-25 | 北京农学院 | Linoleic acid miticide and preparation method thereof |
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