CN104840361A - Cord blood collection and separation blood bag - Google Patents
Cord blood collection and separation blood bag Download PDFInfo
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- CN104840361A CN104840361A CN201510288436.XA CN201510288436A CN104840361A CN 104840361 A CN104840361 A CN 104840361A CN 201510288436 A CN201510288436 A CN 201510288436A CN 104840361 A CN104840361 A CN 104840361A
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Abstract
The invention relates to the field of medical instruments, in particular to a cord blood collection and separation blood bag. The cord blood collection and separation blood bag has the advantages that two inlet needles are adopted, replacement of needle heads or blood collection bags is not needed when first puncture fails or the needle heads are blocked, and accordingly, time and cost are saved; the diameters of needle holes are large, so that blood collection speed is increased, blood blocking is reduced and quality of cord blood is guaranteed; the oval bottom of the blood bag and the oval lower portion of a bag body can be erected, the middle is narrow and the upper portion is wide and flat, so that the blood bag can be erected on a super-clean platform during separation, and suspension of the blood bag and transfer of blood to other containers are not needed; due to an upright cover opening, a blood transfer pipe or Pasteur pipet is conveniently used for collecting cells and cell damage is reduced; the middle of the bag body is narrow, so that hematopoietic stem cell layers can be magnified relatively, cell collection is facilitated and cell loss is reduced; from cord blood collection to cord blood separation, transfer of the blood to other containers is not needed, and accordingly, contamination risk is reduced.
Description
Technical field
The present invention relates to medical instruments field, particularly relate to a kind of cord blood collection and be separated blood bag.
Background technology
Medical research in the last thirty years finds, containing very abundant hematopoietic stem cell (HSC) in Cord blood, human body hemopoietic and immune system can be rebuild, can be used for hematopoietic stem cell transplantation, treatment blood system, immune system, and hereditary metabolic disorders and congenital diseases.Therefore, Cord blood has become the important sources of hematopoietic stem cell, has been widely used in clinical, is valuable human biological's resource.In order to ensure to be applied to clinical umbilical blood not microbial contamination, except adopting advanced person, reliably antibacterial culturing detection system detection technique, the pollution rate how strictly controlling cord blood collection and separation process microorganism is of crucial importance.
Whether successfully umbilical blood from collecting utilization, and successfully whether the conclusive first step to gather, then to separation process.Gatherer process needs to keep aseptic, and separation process needs omnidistance sterile working especially.According to statistics, open collection pollution rate up to 12.5%, seal be then reduced to 3.3%, after being separated, in Cell sap, antibacterial and fungus recall rate are respectively: closed is up to 8.0% and 2.0%, open, is 12% and 2.0%.In blood sampling volume, the previous common blood taking bag successful acquisition umbilical blood amount of order is approximately 70mL, in a lot of situation, the umbilical blood amount of a baby can reach 200mL, the major reason affecting blood sampling volume is gatherer process overlong time, blood coagulation, gets lodged in pin hole position, causes blood sampling volume even deficiency on the low side etc.Further, current blood taking bag needs to hang mostly, uses very inconvenient in blood collection procedure.Further, after umbilical blood is separated, topmost one deck is water and blood plasma, and intermediate layer is hematopoietic stem cell layer, and bottom one deck is other heteroproteose cell layers such as erythrocyte.Wide in the middle part of existing blood bag bag, the hematopoietic stem cell layer after separation is thinner, is unfavorable for the collection of cell.
Summary of the invention
In view of this, the technical problem to be solved in the present invention is to provide a kind of cord blood collection to be separated blood bag.This blood bag is easy to use, mustn't transfer to other containers and just can be separated, and blood sampling volume abundance can effective isolating hematopoietic stem cells.
Cord blood collection provided by the invention is separated blood bag, be provided with in bag (14) top blood transfusion socket (1), can opening neck (3) and bag conduit (4);
Be oval bottom bag, middle part is shunk, and top is wide flat;
Son (2) of can uncapping can be configured with by opening neck (3);
Bag conduit (4) connects the first needle catheter (7) and the second needle catheter (7 ') through threeway (6); First needle catheter connects the first blood taking needle (12); Second needle catheter connects the second blood taking needle (12 ');
Bag conduit (4), the first needle catheter (7) and the second needle catheter (7 ') configuration flow-stopping clip.
Provided by the invention can opening neck with can uncap son coordinate, can be uncapped by outward turning mode.Pipet easy to use or pasteur pipet collecting cell, less primary cellular defect and pollution.
After umbilical blood is separated, topmost one deck is water and blood plasma, intermediate layer is hematopoietic stem cell layer, bottom one deck is other heteroproteose cell layers such as erythrocyte, cord blood collection provided by the invention is separated blood bag, slightly narrow in the middle part of bag, can relatively amplify hematopoietic stem cell layer height, be beneficial to collecting cell, reduce cell depletion.
As preferably, the first blood taking needle arranges the first syringe needle (11) and the first syringe needle handle (9); Described first syringe needle (11) configures the first needle protective cap (10); Second blood taking needle arranges the second syringe needle (11 ') and the second syringe needle handle (9 '); Described second syringe needle (11 ') configures the second needle protective cap (10 ').
Preferably, the internal diameter of the first syringe needle (11) and the second syringe needle (11 ') is 2.0mm.
As preferably, the length of bag conduit is 20cm.
Blood sampling conduit connects the conduit of two blood taking needles at 20cm place by tee T, in case puncture failure or blood coagulation blocking pin hole; Increase thick blood taking needle aperture, blood sampling speed can be increased, reduce blood blocking, ensure umbilical blood quality.
As preferably, the diameter of blood transfusion socket (1) is 0.5cm.
As preferably, can the diameter of opening neck (3) be 2.0cm.
As preferably, in the middle part of bag with bag bottom diameter than being 1:2 ~ 3.
Preferably, in the middle part of bag with bag bottom diameter than for 1:2.5.
Preferred, bag mid diameter is 4.8cm; Base diameter is 12cm, the wide 10cm in top.
As preferably, bottom bag (14), base (13) is set.
As preferably, the volume of bag is 250mL.
Cord blood collection provided by the invention is separated blood bag, be provided with in bag (14) top blood transfusion socket (1), can opening neck (3) and bag conduit (4); Be oval bottom bag, middle part is shunk, and top is wide flat;
Son (2) of can uncapping can be configured with by opening neck (3); Bag conduit (4) connects the first needle catheter (7) and the second needle catheter (7 ') through threeway (6); First needle catheter connects the first blood taking needle (12); Second needle catheter connects the second blood taking needle (12 '); Bag conduit (4), the first needle catheter (7) and the second needle catheter (7 ') configuration flow-stopping clip.Cord blood collection provided by the invention is separated blood bag, adopts two inserting needles: do not need when one-time puncture is unsuccessful or syringe needle blocks to change syringe needle, or change blood taking bag, save time and cost.Pin hole footpath is thick: increase blood sampling speed, reduces blood blocking, ensures umbilical blood quality.Erectile oval bottom and oval bag bottom, middle part is slightly narrow, and upper part is wide flat, and during separation, blood taking bag can uprightly be placed on super-clean bench, does not need hang or migrate out other container.Uprightly to uncap opening, pipet easy to use or pasteur pipet collecting cell, less primary cellular defect.Slightly narrow in the middle part of bag, can relatively amplify hematopoietic stem cell layer, be beneficial to collecting cell, reduce cell depletion.From cord blood collection to separation process, do not need to be transferred to other containers, decreasing pollution risk.
Accompanying drawing explanation
Fig. 1 shows that cord blood collection provided by the invention is separated blood bag; Wherein, 1 shows blood transfusion socket; 2 show son of can uncapping; 3 show can opening neck; 4 show bag conduit; The 5 conduit flow-stopping clips showing bag; 6 show tee T; 7 show the first needle catheter; 7 ' shows the second needle catheter; 8 show the first needle catheter flow-stopping clip; 8 ' shows the second needle catheter flow-stopping clip; 9 show the first syringe needle hands handle; 9 ' shows the second syringe needle hands handle; 10 show the first needle protective cap; 10 ' shows the second needle protective cap; 11 show the first syringe needle; 11 ' shows the second syringe needle; 12 show the first needle handle; 12 ' shows the second needle handle; 13 show base; 14 show bag.
Detailed description of the invention
The invention provides a kind of cord blood collection and be separated blood bag, those skilled in the art can use for reference present disclosure, and suitable improving technique parameter realizes.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the art, they are all deemed to be included in the present invention.Method of the present invention and application are described by preferred embodiment, related personnel obviously can change methods and applications herein or suitably changes and combination not departing from content of the present invention, spirit and scope, realizes and applies the technology of the present invention.
The instrument that the present invention adopts is all common commercially available product, all can buy in market.
Below in conjunction with embodiment, set forth the present invention further:
Embodiment 1
As shown in Figure 1:
Cord blood collection provided by the invention be separated blood bag be provided with on bag (14) top blood transfusion socket (1), can opening neck (3) and bag conduit (4); Be oval bottom bag, middle part is shunk, and top is wide flat; Son (2) of can uncapping can be configured with by opening neck (3); Bag conduit (4) connects the first needle catheter (7) and the second needle catheter (7 ') through threeway (6); First needle catheter connects the first blood taking needle (12); Described second needle catheter connects the second blood taking needle (12 '); Bag conduit (4), the first needle catheter (7) and the second needle catheter (7 ') configuration flow-stopping clip.
Blood bag provided by the invention arranges three flow-stopping clips altogether, is respectively (5), (8), (8 ').
In order to avoid changing syringe needle or blood bag when one-time puncture is unsuccessful or syringe needle blocks, blood bag provided by the invention arranges two blood taking needles, and the first blood taking needle arranges the first syringe needle (11) and the first syringe needle handle (9); Described first syringe needle (11) configures the first needle protective cap (10); Second blood taking needle arranges the second syringe needle (11 ') and the second syringe needle handle (9 '); Described second syringe needle (11 ') configures the second needle protective cap (10 ').
Blood bag provided by the invention, the internal diameter of the first syringe needle (11) and the second syringe needle (11 ') is 2.0mm.
The length of bag conduit is 20cm.The diameter of blood transfusion socket (1) is 0.5cm.Can the diameter of opening neck (3) be 2.0cm.Bag (14) bottom arranges base (13).The volume of bag is 250mL.In the middle part of bag with bag bottom diameter than for 1:2.5.Bag mid diameter is 4.8cm; Base diameter is 12cm, the wide 10cm in top.
Below be only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (10)
1. cord blood collection is separated a blood bag, it is characterized in that, bag (14) top be provided with blood transfusion socket (1), can opening neck (3) and bag conduit (4);
Be oval bottom described bag, middle part is shunk, and top is wide flat;
Describedly can be configured with son (2) of can uncapping by opening neck (3);
Described bag conduit (4) connects the first needle catheter (7) and the second needle catheter (7 ') through tee T (6); Described first needle catheter connects the first blood taking needle (12); Described second needle catheter connects the second blood taking needle (12 ');
Described bag conduit (4), the first needle catheter (7) and the second needle catheter (7 ') configuration flow-stopping clip.
2. cord blood collection according to claim 1 is separated blood bag, and it is characterized in that, described first blood taking needle arranges the first syringe needle (11) and the first syringe needle handle (9); Described first syringe needle (11) configures the first needle protective cap (10); Second blood taking needle arranges the second syringe needle (11 ') and the second syringe needle handle (9 '); Described second syringe needle (11 ') configures the second needle protective cap (10 ').
3. cord blood collection according to claim 2 is separated blood bag, and it is characterized in that, the internal diameter of described first syringe needle (11) and the second syringe needle (11 ') is 2.0mm.
4. cord blood collection according to claim 1 is separated blood bag, and it is characterized in that, the length of described bag conduit is 20cm.
5. cord blood collection according to claim 1 is separated blood bag, and it is characterized in that, the diameter of described blood transfusion socket (1) is 0.5cm.
6. cord blood collection according to claim 1 is separated blood bag, it is characterized in that, described can the diameter of opening neck (3) be 2.0cm.
7. cord blood collection according to claim 1 is separated blood bag, it is characterized in that, in the middle part of described bag with bag bottom diameter than being 1:2 ~ 3.
8. cord blood collection according to claim 1 is separated blood bag, it is characterized in that, in the middle part of described bag with bag bottom diameter than being 1:2.5.
9. cord blood collection according to claim 1 is separated blood bag, it is characterized in that, described bag (14) bottom arranges base (13).
10. the cord blood collection according to any one of claim 1 ~ 9 is separated blood bag, and it is characterized in that, the volume of described bag is 250mL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510288436.XA CN104840361B (en) | 2015-05-29 | 2015-05-29 | A kind of cord blood collection separation blood bag |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510288436.XA CN104840361B (en) | 2015-05-29 | 2015-05-29 | A kind of cord blood collection separation blood bag |
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| CN104840361A true CN104840361A (en) | 2015-08-19 |
| CN104840361B CN104840361B (en) | 2018-12-04 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107723226A (en) * | 2017-11-15 | 2018-02-23 | 浙江绿蔻生物技术有限公司 | Blood sampling separation bag |
| CN109943470A (en) * | 2019-03-26 | 2019-06-28 | 深圳市第二人民医院 | A kind of cord blood stem cell collection device |
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| CN2684821Y (en) * | 2003-04-25 | 2005-03-16 | 上海再胜源干细胞工程有限公司 | Cord blood collecting and separating bag |
| JP4034850B2 (en) * | 1997-06-16 | 2008-01-16 | ニプロ株式会社 | Cryopreservation bag |
| CN201127611Y (en) * | 2007-12-26 | 2008-10-08 | 协和干细胞基因工程有限公司 | Bag for collecting cord blood |
| CN201782962U (en) * | 2010-09-01 | 2011-04-06 | 湖南光琇高新生命科技有限公司 | Special integrated bag for umbilical cord blood stem cell collection and separation |
| CN202236310U (en) * | 2011-09-28 | 2012-05-30 | 山东威高集团医用高分子制品股份有限公司 | Cord blood collecting and separating bag |
| CN203252914U (en) * | 2013-05-08 | 2013-10-30 | 四川南格尔生物医学股份有限公司 | Cord blood collecting and separating integrated bag with profound hypothermia preservation bag |
| CN204798372U (en) * | 2015-05-29 | 2015-11-25 | 广州赛莱拉干细胞科技股份有限公司 | Bleeding of umbilicus collection separation blood bag |
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2015
- 2015-05-29 CN CN201510288436.XA patent/CN104840361B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4034850B2 (en) * | 1997-06-16 | 2008-01-16 | ニプロ株式会社 | Cryopreservation bag |
| CN2684821Y (en) * | 2003-04-25 | 2005-03-16 | 上海再胜源干细胞工程有限公司 | Cord blood collecting and separating bag |
| CN201127611Y (en) * | 2007-12-26 | 2008-10-08 | 协和干细胞基因工程有限公司 | Bag for collecting cord blood |
| CN201782962U (en) * | 2010-09-01 | 2011-04-06 | 湖南光琇高新生命科技有限公司 | Special integrated bag for umbilical cord blood stem cell collection and separation |
| CN202236310U (en) * | 2011-09-28 | 2012-05-30 | 山东威高集团医用高分子制品股份有限公司 | Cord blood collecting and separating bag |
| CN203252914U (en) * | 2013-05-08 | 2013-10-30 | 四川南格尔生物医学股份有限公司 | Cord blood collecting and separating integrated bag with profound hypothermia preservation bag |
| CN204798372U (en) * | 2015-05-29 | 2015-11-25 | 广州赛莱拉干细胞科技股份有限公司 | Bleeding of umbilicus collection separation blood bag |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107723226A (en) * | 2017-11-15 | 2018-02-23 | 浙江绿蔻生物技术有限公司 | Blood sampling separation bag |
| CN109943470A (en) * | 2019-03-26 | 2019-06-28 | 深圳市第二人民医院 | A kind of cord blood stem cell collection device |
| CN109943470B (en) * | 2019-03-26 | 2022-06-17 | 深圳市第二人民医院 | Cord blood stem cell collector |
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| CN104840361B (en) | 2018-12-04 |
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