CN202497449U - Three-combination bag used for collection, separation and preservation of umbilical cord blood - Google Patents
Three-combination bag used for collection, separation and preservation of umbilical cord blood Download PDFInfo
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- CN202497449U CN202497449U CN2012200754378U CN201220075437U CN202497449U CN 202497449 U CN202497449 U CN 202497449U CN 2012200754378 U CN2012200754378 U CN 2012200754378U CN 201220075437 U CN201220075437 U CN 201220075437U CN 202497449 U CN202497449 U CN 202497449U
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Abstract
A three-combination bag used for collection, separation and preservation of umbilical cord blood is characterized in that: the three-combination bag comprises a blood collection bag which is provided with a needle which is connected with the blood collection bag through a connecting tube; a separation bag which is connected with the blood collection bag through a first catheter which is provided with a first control valve; and a preservation bag which is provided with an orifice and is connected with the separation bag through a second catheter which is provided with a second control valve.
Description
Technical field
This utility model relates to a kind of medical apparatus, more specifically, relates to a kind of three bags that are used for cord blood collection, separation, preservation.
Background technology
Along with stem cell especially deepening continuously of navel blood stem cell clinical application research, umbilical blood stores and also more and more receives extensive concern.Cord blood collection, separation, preserve each link and all have material impact for the quality that stores umbilical blood.At present, gather, separate, preserve and use discrete bag to accomplish respectively, perhaps wherein two steps adopt the one bag to accomplish.Adopt a plurality of bags to be prone to cause when connecting these bags, increased the contaminated risk of navel blood stem cell.In addition, according to present cord blood collection, separation, store method, cord blood collection needs 1 bag at least, separates at least and need 2 bags, preservations need 1 bag, amounts to 4 bags, has increased the cost that umbilical blood stores.
China's utility model patent 99239764.2 discloses a kind of Cord blood and has separated to preserve to join bag more, comprises 1 main bag, 1 pair bag, 2 cryopreservation bags, amounts to 4 bags.Wherein leading bag needs to link to each other with a cord blood collection bag in addition, and therefore whole cord blood collection, separation, preservation link are used 5 bags altogether.And it is discrete with the cord blood collection bag that the bags that join are preserved in the separation of this utility model more.
In addition, Chinese utility model patent 201020511739.6 discloses a kind of navel blood stem cell and has gathered separate, dedicated one bag, and it is made up of 1 main blood bag and 1 secondary blood bag.The collection separation bag and the storage bag of this utility model are discrete.
The utility model content
A purpose of this utility model provides a kind of integrated apparatus that is used for cord blood collection, separation, preservation with fewer purpose bag.
This utility model solves the problems referred to above through a kind of three bags that are used for cord blood collection, separation, preservation, and said three bags comprise:
A blood taking bag, said blood taking bag have a syringe needle, and this syringe needle is connected in blood taking bag through connection tube;
A separation bag, said separation bag links to each other through first conduit with said blood taking bag, and this first conduit is equipped with first control valve;
A storage bag, said storage bag links to each other through second conduit with said separation bag, and this second conduit is equipped with second control valve, and said storage bag has a mouth of pipe.
Three bags that are used for cord blood collection, separation, preservation of this utility model can effectively avoid the risk that pollutes when the sack of each link with separation connects respectively gathering, separating, preserve, have improved the safety of cord blood collection, separation, storage.In addition, the blood taking bag of this utility model mainly plays the blood sampling function when gathering Cord blood; When blood taking bag adds hetastarch, can be in wherein playing the Cord blood separation function; When from separation bag, being transferred to blood plasma in the blood taking bag, blood taking bag plays the function of collecting waste liquid; Therefore three bags of this utility model have utilized blood taking bag to greatest extent, have practiced thrift consumptive material, have reduced cost.
In a preferred embodiment, said first control valve and/or said second control valve are control ski-running wheel, so that controllably regulate the flow rate of fluid of flow through said first conduit and/or second conduit.
In a preferred embodiment, the volume of said blood taking bag and/or said separation bag is respectively 50-350ml, and the volume of said storage bag is 20-100ml.More preferably, the volume of said blood taking bag and/or said separation bag is respectively 100-350ml, and the volume of said storage bag is 30-100ml.
In a preferred embodiment, the syringe needle of said blood taking bag has a pin medicated cap.
In a preferred embodiment, said blood taking bag also has a mouth of pipe, is used to inject hetastarch and/or other processing medicaments.In a further advantageous embodiment; The syringe needle of said blood taking bag removably connects, and after blood sampling finishes, pulls out said syringe needle; The connection tube that can will link to each other with said syringe needle is as the mouth of pipe that injects hetastarch and/or other processing medicaments; With the saving material, thereby make said blood taking bag need not to have in addition the mouth of pipe, just can accomplish its effect.
In a preferred embodiment; When said second conduit being broken off so that stores said storage bag; In second conduit, remain with the section that is full of umbilical blood of three separations near said storage bag; Make need transplant the umbilical blood of being stored afterwards before, can carry out umbilical blood quality testing or analysis etc. by the intercepting segment.
In a preferred embodiment, the bag of said blood taking bag, said separation bag and/or said storage bag has scale, with the convenient blood volume of observing.
In a preferred embodiment, the bag top of said blood taking bag, said separation bag and/or said storage bag is square or pointed shape, more preferably pointed shape.Perhaps, the bag bottom of said blood taking bag, said separation bag and/or said storage bag is square or pointed shape, and pointed shape more preferably is to improve the monocytic response rate.
Description of drawings
Describe the exemplary of this utility model below in conjunction with accompanying drawing, from said description, can be expressly understood the above-mentioned of this utility model and other aspects, feature and advantage.In said accompanying drawing:
Fig. 1 is the sketch map that of this utility model is used for three bags of cord blood collection, separation, preservation.
The specific embodiment
Hereinafter will specifically describe the embodiment of three bags of this utility model with reference to accompanying drawing.Accompanying drawing is not necessarily drawn in proportion.Should be appreciated that following embodiment and accompanying drawing only are illustrative, should not be regarded as limiting the scope of this utility model.
In this manual, term " first ", " second " are in order to distinguish the different parts of same classification, and do not constitute concrete restriction.
With reference to Fig. 1, three bags of this embodiment comprise blood taking bag 1, separation bag 2, storage bag 3.Said blood taking bag 1 is connected through first conduit 4 with separation bag 2, and separation bag 2 is connected through second conduit 4 ' with storage bag 3.First conduit 4 is equipped with first control valve, 6, the second conduits 4 ' second control valve 6 ' is installed.Wherein, said first control valve 6 and second control valve 6 ' are preferably control ski-running wheel.
Blood taking bag 1 top is connected with a syringe needle 7, and this syringe needle can comprise a pin medicated cap 8.Blood taking bag 1 top also has a mouth of pipe 5, and this mouth of pipe 5 is used for injecting hetastarch or other handle medicament, so that sedimented red cell.
Storage bag 3 tops have a mouth of pipe 5 ', and this mouth of pipe 5 ' is used for injecting the umbilical blood mononuclear cell and preserves liquid or other cryopreserving liquids, so that freezing preservation umbilical blood.
The volume of said blood taking bag 1 and/or said separation bag 2 is respectively 50-350ml, is preferably 100-350ml.The volume of said storage bag 3 is 20-100ml, is preferably 30-100ml.
The bag top of said blood taking bag 1, said separation bag 2 and/or said storage bag 3 can be preferably pointed shape for square or pointed shape; The bag bottom of perhaps said blood taking bag 1, said separation bag 2 and/or said storage bag 3 can be preferably pointed shape for square or pointed shape.The bag of said blood taking bag 1, said separation bag 2 and/or said storage bag 3 has scale, with the convenient blood volume of observing, what wherein said scale can be for recessed or protrusion.
The concrete applying examples of three bags in cord blood collection, separation, preservation process of this utility model will be described below.In the cord blood collection step, at first pull up pin medicated cap 8, blood taking needle 7 is inserted in the fetal cord blood vessel take a blood sample, and connect first conduit 4 of blood taking bag 1 and separation bag 2 through 6 sealings of first control valve.After blood sampling finished, the conduit that will connect syringe needle with the heat seal device sealed, and sends into the processing that laboratory carries out umbilical blood.The mouth of pipe 5 through blood taking bag 1 top adds the hetastarch of botal blood volumes 20% percent by volume, and the rotation of turning upside down then makes its abundant mixing.Seal first control valve 6, equilibrium centrifugation power, the blood taking bag 1 that adds hetastarch is centrifugal, centrifugation rate 750rpm, room temperature (for example, 20-30 ℃), centrifugal 8 minutes.
After the centrifugal end, blood taking bag 1 is just being hung up, erythrocyte is opened first conduit 4 that connects blood taking bag 1 and separation bag 2 in the bottom through first control valve 6, will contain the monocytic blood plasma of umbilical blood and be transferred in the separation bag 2.After blood plasma shifts, through first conduit 4 between first control valve, 6 sealing blood taking bags 1 and the separation bag 2, and through second conduit 4 ' between second control valve, 6 ' sealing separation bag 2 and the storage bag 3.
After accomplishing above-mentioned steps, that is, and after will containing monocytic blood plasma and transferring to separation bag 2 and first conduit 4 and the 4 ' sealing of second conduit, to separation bag 2 centrifugal treating.Wherein, separation bag 2 is positioned at upright direction, centrifugation rate 1500rpm, room temperature (for example, 20-30 ℃), centrifugal 10 minutes.After the centrifugal completion, bottom is a mononuclear cell, and the upper strata is a blood plasma.Open first control valve 6, the blood plasma on upper strata is transferred in the blood taking bag 1.Open second control valve 6 ', mononuclear cell is transferred in the storage bag 3.
Then, the mouth of pipe 5 ' through storage bag 3 tops injects the umbilical blood mononuclear cell and preserves liquid in storage bag 3, and with its abundant mixing.The preservation liquid that adds storage bag 3 can be transferred in the separation bag 2 repeatedly, and the mononuclear cell after blood plasma in the separation bag 2 is shifted washes, and reduces the loss of the mononuclear cell number in the umbilical blood to greatest extent, increases cell content.
After mononuclear cell is transferred to storage bag 3, under 5-10 ℃ temperature conditions, will contain monocytic storage bag and place 20 minutes, according to the programmed cooling appearance storage bag is carried out programmed cooling then, and it is transferred in the nitrogen storage tank.
When the said storage bag of storage, second conduit 4 ' that can directly use the heat seal device will connect said separation bag 2 and said storage bag 3 breaks off, and separately said storage bag 3 is placed in the holding vessel, thereby saves memory space.In addition, when said second conduit 4 ' is broken off, in second conduit 4 ' near storage bag 3, remain with the section that is full of umbilical blood of three separations, every section can be for example 2 centimeter length, separates through the heat seal of heat seal device between every section.Before this helps need transplanting umbilical blood afterwards, can carry out the umbilical blood quality testing by the intercepting segment, like virus, microorganism, mycoplasma, caryogram, gene analysis etc.When confirming to need to use the umbilical blood of storage in the storage bag 3, can the umbilical blood in it be taken out through the mouth of pipe 5 ' on storage bag 3 tops.
The content that it should be understood that this utility model is not limited to the above embodiments.Under the situation of spirit that does not depart from accompanying claims and scope; Can carry out multiple modification and replacement to present disclosure; For example can select combination to above-mentioned technical characterictic, said multiple modification and replacement all are interpreted as dropping in the protection domain of this utility model.
Claims (10)
1. three bags that are used for cord blood collection, separation, preservation is characterized in that, comprising:
A blood taking bag, said blood taking bag have a syringe needle, and this syringe needle is connected in blood taking bag through connection tube;
A separation bag, said separation bag links to each other through first conduit with said blood taking bag, and this first conduit is equipped with first control valve;
A storage bag, said storage bag links to each other through second conduit with said separation bag, and this second conduit is equipped with second control valve, and said storage bag has a mouth of pipe.
2. three bags according to claim 1 is characterized in that, said first control valve and/or said second control valve are control ski-running wheel.
3. three bags according to claim 1 is characterized in that the volume of said blood taking bag and/or said separation bag is respectively 50-350ml, and the volume of said storage bag is 20-100ml.
4. three bags according to claim 3 is characterized in that the volume of said blood taking bag and/or said separation bag is respectively 100-350ml, and the volume of said storage bag is 30-100ml.
5. three bags according to claim 1 is characterized in that, the syringe needle of said blood taking bag has a pin medicated cap.
6. three bags according to claim 1 is characterized in that, said blood taking bag also has a mouth of pipe; Perhaps the syringe needle of said blood taking bag removably connects, and after blood sampling finishes, pulls out said syringe needle, and the connection tube that can will link to each other with said syringe needle is as a mouth of pipe.
7. three bags according to claim 1 is characterized in that, said second conduit are broken off when storing said storage bag, near second conduit of said storage bag, keep the section that is full of umbilical blood of three separations.
8. three bags according to claim 1 is characterized in that, the bag of said blood taking bag, said separation bag and/or said storage bag has scale.
9. require each described three bags according to aforesaid right, it is characterized in that, the bag top of said blood taking bag, said separation bag and/or said storage bag is square or pointed shape; And/or the bag bottom of said blood taking bag, said separation bag and/or said storage bag is square or pointed shape.
10. three bags according to claim 9 is characterized in that, the bag top of said blood taking bag, said separation bag and/or said storage bag and/or bag bottom are pointed shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012200754378U CN202497449U (en) | 2012-03-02 | 2012-03-02 | Three-combination bag used for collection, separation and preservation of umbilical cord blood |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012200754378U CN202497449U (en) | 2012-03-02 | 2012-03-02 | Three-combination bag used for collection, separation and preservation of umbilical cord blood |
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| Publication Number | Publication Date |
|---|---|
| CN202497449U true CN202497449U (en) | 2012-10-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012200754378U Expired - Lifetime CN202497449U (en) | 2012-03-02 | 2012-03-02 | Three-combination bag used for collection, separation and preservation of umbilical cord blood |
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| Country | Link |
|---|---|
| CN (1) | CN202497449U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769005A (en) * | 2016-05-10 | 2016-07-20 | 徐静 | Obstetrics assist device with umbilical cord blood preservation function |
| CN106618601A (en) * | 2017-03-03 | 2017-05-10 | 浙江绿蔻生物技术有限公司 | Umbilical cord blood bag |
| CN110229788A (en) * | 2019-04-11 | 2019-09-13 | 广州市天河诺亚生物工程有限公司 | A kind of preparation method of cord blood mononuclear cells |
-
2012
- 2012-03-02 CN CN2012200754378U patent/CN202497449U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769005A (en) * | 2016-05-10 | 2016-07-20 | 徐静 | Obstetrics assist device with umbilical cord blood preservation function |
| CN106618601A (en) * | 2017-03-03 | 2017-05-10 | 浙江绿蔻生物技术有限公司 | Umbilical cord blood bag |
| CN110229788A (en) * | 2019-04-11 | 2019-09-13 | 广州市天河诺亚生物工程有限公司 | A kind of preparation method of cord blood mononuclear cells |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200525 Address after: 215000 Room 204 and 205, building A5, bio nano Park, 218 Xinghu street, Suzhou Industrial Park, Jiangsu Province Patentee after: Palmer biomedical testing (Suzhou) Co., Ltd Address before: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215021 Xinghu Street No. 218 BioBAY A5 building room 201-206 Patentee before: HOPE BIOLOGICAL TECHNOLOGY (SUZHOU) Co.,Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20121024 |