CN104815249A - Traditional Chinese medicine preparation for treating stichopus japonicus ulcerative syndrome with high cure rate and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating stichopus japonicus ulcerative syndrome with high cure rate and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating stichopus japonicus ulcerative syndrome with high cure rate. The traditional Chinese medicine preparation comprises the following components in parts by weight: 25-35 parts of herba andrographitis, 15-25 parts of honeysuckle, 15-25 parts of Scutellaria baicalensis, 25-35 parts of gallnut, 3 parts of Hedyotis diffusa, 5 parts of dandelion, 4 parts of viola, 3 parts of patrinia, 2 parts of rhizoma smilacis glabrae, 5 parts of mother chrysanthemum, 2 parts of subprostrate sophora, 3 parts of radix sophorae flavescentis, 4 parts of radix semiaquilegiae, 3 parts of semen plantaginis, 4 parts of pericarpium arecae, 4 parts of junci medulla, 2 parts of Bletilla, 3 parts of rhizoma nelumbinis and 2 parts of hedgehog hide. Compared with a common medicine, the traditional Chinese medicine preparation has the advantages as follows: the cost of the preparation is reduced by 40%, the dosage is reduced by 60% and the cure rate is increased by 20-25%. The nutrient content of the stichopus japonicus fed with the product prepared by the invention is increased. The product is high in bioavailability, low in addition amount, fed together bait and is convenient to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, specifically a kind ofly treat Chinese medicine preparation of Radix Morinae Bulleyanae skin ulcerative syndrome and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Radix Morinae Bulleyanae " skin ulcerative syndrome " (being commonly called as skin is sick) is the main disease of current cultivation Radix Morinae Bulleyanae, mortality rate can reach more than 90%, belong to acute death, survive the winter keep a full stand of seedings the phase children ginseng and mature stage Radix Morinae Bulleyanae all can infectedly fall ill, be one of disease that current apostichopus japonicus culture is the most common, harm is the most serious, seriously constrain the sustainable and healthy development of apostichopus japonicus culture industry.The disease symptom of Radix Morinae Bulleyanae skin ulcerative syndrome shows as: shake the head, oral area enlargement, arrange dirty, health atrophy, oral area festers, body surface ulcer is until dissolve dead.Cause the reason of Radix Morinae Bulleyanae generation skin ulcerative syndrome a lot, the factor of existing feeding and management aspect, also in water environment, a large amount of pathogenic bacterium are infected and cause, the control of current Radix Morinae Bulleyanae skin ulcerative syndrome depends on chemosterilant and antibiotic, there is following defect in prior art: (1) cost is high, and consumption is high; (2) cure rate is low.Life-time service can cause drug residue, pathogen produces the problem such as drug resistance and water body environment pollution, drastically influence the development of culture fishery.
Summary of the invention
In order to solve the problem, the invention provides a kind of Chinese medicine preparation and preparation method for the treatment of Radix Morinae Bulleyanae skin ulcerative syndrome, realizing following goal of the invention:
(1) cost reduction 40% of this product, consumption reduces 60%, and cure rate improves 20-25%, and relapse rate is 0.
(2) add the Radix Morinae Bulleyanae that product of the present invention is fed, nutrition content improves.
(3) this product can direct bacteriostasis and sterilization, has obvious inhibitory action to antibacterial, also jointly complete kill, suppress in water and the pathogenic bacteria of fish body, parasite, prevent spreading of causal organism; Can regulate again and improve immunity of organisms simultaneously, strengthening aquatic animal resistance against diseases.
Technical scheme of the present invention is:
The Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that a kind of cure rate is high, be grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Hedyotidis Diffusae 3 parts, Herba Taraxaci 5 parts, Herba Violae 4 parts, Herba Patriniae 3 parts, Rhizoma Smilacis Glabrae 2 parts, Flos Chrysanthemi Indici 5 parts, Radix Sophorae Tonkinensis 2 parts, Radix Sophorae Flavescentis 3 parts, Radix Semiaquilegiae 4 parts, Semen Plantaginis 3 parts, Pericarpium Arecae 4 parts, Medulla Junci 4 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 2 parts, Nodus Nelumbinis Rhizomatis 3 parts, Corium Erinacei Seu Hemiechianus 2 parts.
Below the further improvement to technique scheme:
A Chinese medicine preparation for the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, is grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Herba Scutellariae Barbatae 6 parts, Semen Cassiae 4 parts, Cortex Lycii 3 parts, Rhizoma Phragmitis 5 parts, Folium Ginseng 6 parts, Herba Houttuyniae 4 parts, Herba Patriniae 5 parts, Herba Violae 6 parts, Rhizoma Paridis 3 parts, Herba Taraxaci 5 parts, Caulis et Folium cayratiae trifoliae 6 parts, Herba Lysimachiae 4 parts, Polyporus 5 parts, Herba Agrimoniae 6 parts, Folium Callicarpae Formosanae 5 parts, charred Petiolus Trachycarpi 4 parts, Radix Notoginseng 5 parts.
A Chinese medicine preparation for the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, is grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Herba Kalimeridis grass 4 parts, field thistle 5 parts, 3 parts, Flos Sophorae, Flos Hibisci 5 parts, Flos Campsis 4 parts, Flos Celosiae Cristatae 6 parts, Herba Artemisiae Annuae 3 parts, Radix Scrophulariae 1 part, Radix Rehmanniae 2 parts, Radix et Caulis Opuntiae Dillenii 6 parts, Exocarpium Benincasae 5 parts, Pollen Typhae 3 parts, 6 parts, Radix Rubiae, Crinis Carbonisatus 2 parts, 5 parts, Folium Mori, Folium Lycii 4 parts, Flos Chrysanthemi 4 parts, 4 parts, Herba Dendranthematis indici, Spica Prunellae 5 parts.
A preparation method for the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, comprises the following steps: get the raw materials ready, Radix Scutellariae is cut into slices, pulverize and mixing.
Described Radix Scutellariae slicing step, by the Radix Scutellariae cutting taken, removing impurity, puts in boiling water and boils 10 minutes, takes out, braised through, and shave is dry.
Also comprise Nodus Nelumbinis Rhizomatis parch to black step, fry burned black to appearance by Nodus Nelumbinis Rhizomatis, the inside is sallow, takes out and puts in iron pan or porcelain dish, spread out cold rear stand-by.
Described pulverising step, is ground into 300 object powder respectively by various raw material super micron mill.
Described blend step, by the powder of various raw materials obtained, by weight mix homogeneously, this tcm product obtained.
The present invention compared with prior art has following beneficial effect:
(1) compared with common drug, the cost reduction 40% of this medicament, consumption reduces 60%, and cure rate can improve 20-25%.
(2) add the Radix Morinae Bulleyanae that product of the present invention is fed, nutrition content improves, and in aminoacid composition, TEAA improves 5%, and Fresh ear field total amount and drug effect total amino acid content improve 6%.
(3) this product bioavailability is high, and addition is little, mixes erbium and throws something and feeds, easy to use.
(4) pure Chinese medicinal preparation, does not produce drug resistance, and prolonged application has no side effect.
(5) with residual without hazardous drugs in the Radix Morinae Bulleyanae body after we's treatment, food to human body without any harmful effect, be desirable green non-pollution fisheries drug product.
(6) this product can direct bacteriostasis and sterilization, has obvious inhibitory action to antibacterial, also jointly complete kill, suppress in water and the pathogenic bacteria of fish body, parasite, prevent spreading of causal organism; Can regulate again and improve immunity of organisms simultaneously, strengthening aquatic animal resistance against diseases.
(7) raw materials enjoy stable sources, reliable in quality, production technology is simple, relative low price.
Detailed description of the invention
Below the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein is only for instruction and explanation of the present invention, is not intended to limit the present invention.
Embodiment 1
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 30 parts, Flos Lonicerae 20 parts, Radix Scutellariae 20 parts, Galla Chinensis 30 parts, Hedyotidis Diffusae 3 parts, Herba Taraxaci 5 parts, Herba Violae 4 parts, Herba Patriniae 3 parts, Rhizoma Smilacis Glabrae 2 parts, Flos Chrysanthemi Indici 5 parts, Radix Sophorae Tonkinensis 2 parts, Radix Sophorae Flavescentis 3 parts, Radix Semiaquilegiae 4 parts, Semen Plantaginis 3 parts, Pericarpium Arecae 4 parts, Medulla Junci 4 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 2 parts, Nodus Nelumbinis Rhizomatis 3 parts, Corium Erinacei Seu Hemiechianus 2 parts.
Embodiment 2
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 25 parts, Flos Lonicerae 15 parts, Radix Scutellariae 15 parts, Galla Chinensis 25 parts, Hedyotidis Diffusae 3 parts, Herba Taraxaci 5 parts, Herba Violae 4 parts, Herba Patriniae 3 parts, Rhizoma Smilacis Glabrae 2 parts, Flos Chrysanthemi Indici 5 parts, Radix Sophorae Tonkinensis 2 parts, Radix Sophorae Flavescentis 3 parts, Radix Semiaquilegiae 4 parts, Semen Plantaginis 3 parts, Pericarpium Arecae 4 parts, Medulla Junci 4 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 2 parts, Nodus Nelumbinis Rhizomatis 3 parts, Corium Erinacei Seu Hemiechianus 2 parts.
Embodiment 3
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 35 parts, Flos Lonicerae 25 parts, Radix Scutellariae 25 parts, Galla Chinensis 35 parts, Hedyotidis Diffusae 4 parts, Herba Taraxaci 5 parts, Herba Violae 5 parts, Herba Patriniae 3 parts, Rhizoma Smilacis Glabrae 3 parts, Flos Chrysanthemi Indici 5 parts, Radix Sophorae Tonkinensis 2 parts, Radix Sophorae Flavescentis 3 parts, Radix Semiaquilegiae 4 parts, Semen Plantaginis 3 parts, Pericarpium Arecae 4 parts, Medulla Junci 4 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 2 parts, Nodus Nelumbinis Rhizomatis 3 parts, Corium Erinacei Seu Hemiechianus 2 parts.
Embodiment 4
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 30 parts, Flos Lonicerae 20 parts, Radix Scutellariae 20 parts, Galla Chinensis 30 parts, Herba Scutellariae Barbatae 6 parts, Semen Cassiae 4 parts, Cortex Lycii 3 parts, Rhizoma Phragmitis 5 parts, Folium Ginseng 6 parts, Herba Houttuyniae 4 parts, Herba Patriniae 5 parts, Herba Violae 6 parts, Rhizoma Paridis 3 parts, Herba Taraxaci 5 parts, Caulis et Folium cayratiae trifoliae 6 parts, Herba Lysimachiae 4 parts, Polyporus 5 parts, Herba Agrimoniae 6 parts, Folium Callicarpae Formosanae 5 parts, charred Petiolus Trachycarpi 4 parts, Radix Notoginseng 5 parts.
Embodiment 5
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 35 parts, Flos Lonicerae 25 parts, Radix Scutellariae 25 parts, Galla Chinensis 35 parts, Herba Scutellariae Barbatae 6 parts, Flos Lonicerae 2 parts, Semen Cassiae 4 parts, Cortex Lycii 3 parts, Rhizoma Phragmitis 5 parts, Folium Ginseng 6 parts, Herba Houttuyniae 4 parts, Herba Patriniae 5 parts, Herba Violae 6 parts, Rhizoma Paridis 3 parts, Herba Taraxaci 5 parts, Caulis et Folium cayratiae trifoliae 6 parts, Herba Lysimachiae 4 parts, Polyporus 5 parts, Herba Agrimoniae 6 parts, Folium Callicarpae Formosanae 5 parts, charred Petiolus Trachycarpi 4 parts, Radix Notoginseng 5 parts.
Embodiment 6
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 25 parts, Flos Lonicerae 15 parts, Radix Scutellariae 15 parts, Galla Chinensis 25 parts, Herba Scutellariae Barbatae 6 parts, Flos Lonicerae 2 parts, Semen Cassiae 4 parts, Cortex Lycii 3 parts, Rhizoma Phragmitis 5 parts, Folium Ginseng 6 parts, Herba Houttuyniae 4 parts, Herba Patriniae 5 parts, Herba Violae 6 parts, Rhizoma Paridis 3 parts, Herba Taraxaci 5 parts, Caulis et Folium cayratiae trifoliae 6 parts, Herba Lysimachiae 4 parts, Polyporus 5 parts, Herba Agrimoniae 6 parts, Folium Callicarpae Formosanae 5 parts, charred Petiolus Trachycarpi 4 parts, Radix Notoginseng 5 parts.
Embodiment 7
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 30 parts, Flos Lonicerae 20 parts, Radix Scutellariae 20 parts, Galla Chinensis 30 parts, Herba Kalimeridis grass 4 parts, field thistle 5 parts, 3 parts, Flos Sophorae, Flos Hibisci 5 parts, Flos Campsis 4 parts, Flos Celosiae Cristatae 6 parts, Herba Artemisiae Annuae 3 parts, Radix Scrophulariae 1 part, Radix Rehmanniae 2 parts, Radix et Caulis Opuntiae Dillenii 6 parts, Exocarpium Benincasae 5 parts, Pollen Typhae 3 parts, 6 parts, Radix Rubiae, Crinis Carbonisatus 2 parts, 5 parts, Folium Mori, Folium Lycii 4 parts, Flos Chrysanthemi 4 parts, 4 parts, Herba Dendranthematis indici, Spica Prunellae 5 parts.
Embodiment 8
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 35 parts, Flos Lonicerae 25 parts, Radix Scutellariae 25 parts, Galla Chinensis 35 parts, Herba Kalimeridis grass 4 parts, field thistle 5 parts, 3 parts, Flos Sophorae, Flos Hibisci 5 parts, Flos Campsis 4 parts, Flos Celosiae Cristatae 6 parts, Herba Artemisiae Annuae 3 parts, Radix Scrophulariae 1 part, Radix Rehmanniae 2 parts, Radix et Caulis Opuntiae Dillenii 6 parts, Exocarpium Benincasae 5 parts, Pollen Typhae 3 parts, 6 parts, Radix Rubiae, Crinis Carbonisatus 2 parts, 5 parts, Folium Mori, Folium Lycii 4 parts, Flos Chrysanthemi 4 parts, 4 parts, Herba Dendranthematis indici, Spica Prunellae 5 parts.
Embodiment 9
Treat a Chinese medicine preparation for Radix Morinae Bulleyanae skin ulcerative syndrome, be grouped into by the one-tenth of following weight parts:
Herba Andrographis 25 parts, Flos Lonicerae 15 parts, Radix Scutellariae 15 parts, Galla Chinensis 25 parts, Herba Kalimeridis grass 4 parts, field thistle 5 parts, 3 parts, Flos Sophorae, Flos Hibisci 5 parts, Flos Campsis 4 parts, Flos Celosiae Cristatae 6 parts, Herba Artemisiae Annuae 3 parts, Radix Scrophulariae 1 part, Radix Rehmanniae 2 parts, Radix et Caulis Opuntiae Dillenii 6 parts, Exocarpium Benincasae 5 parts, Pollen Typhae 3 parts, 6 parts, Radix Rubiae, Crinis Carbonisatus 2 parts, 5 parts, Folium Mori, Folium Lycii 4 parts, Flos Chrysanthemi 4 parts, 4 parts, Herba Dendranthematis indici, Spica Prunellae 5 parts.
Embodiment 10
The preparation method of Chinese medicine described in embodiment 1-3, comprises the following steps:
(1) get the raw materials ready: prepare following crude drug: Herba Andrographis, Flos Lonicerae, Radix Scutellariae, Galla Chinensis, Hedyotidis Diffusae, Herba Taraxaci, Herba Violae, Herba Patriniae, Rhizoma Smilacis Glabrae, Flos Chrysanthemi Indici, Radix Sophorae Tonkinensis, Radix Sophorae Flavescentis, Radix Semiaquilegiae, Semen Plantaginis, Pericarpium Arecae, Medulla Junci, Pseudobulbus Bletillae (Rhizoma Bletillae), Nodus Nelumbinis Rhizomatis, Corium Erinacei Seu Hemiechianus.
(2) Radix Scutellariae section:
By the Radix Scutellariae cutting taken, removing impurity, puts in boiling water and boils 10 minutes, takes out, braised through, and shave is dry; Or steam half an hour, and take out, shave, dry, note avoiding tanning by the sun.
(3) Corium Erinacei Seu Hemiechianus parching to brown:
Corium Erinacei Seu Hemiechianus is fried to appearance coke yellow or burnt brown, inner yellowish, and has burnt odor abnormal smells from the patient.
(4) Nodus Nelumbinis Rhizomatis parch to black
Fry burned black to appearance by Nodus Nelumbinis Rhizomatis, the inside is sallow, and fry rear section carbonization, but still have original abnormal smells from the patient, its temperature is higher than parching to brown, and the time will be grown.Because firepower is comparatively strong during stir-fry, spice is inflammable, if any Mars, sprays appropriate clear water and to go out flame-out star, take out and put in iron pan or porcelain dish, spread out cold rear stand-by.After high-temperature process, generate charcoal element or increase new material, strengthening anastaltic effect.
(5) pulverize
Various raw material super micron mill is ground into 300 object powder respectively.
(6) mix
By the powder of various raw materials obtained, according to the weight ratio mix homogeneously of embodiment 1,2 or 3, this tcm product obtained.
Embodiment 11
The preparation method of Chinese medicine described in embodiment 4-6, comprises the following steps:
(1) get the raw materials ready: prepare following crude drug: Herba Andrographis, Flos Lonicerae, Radix Scutellariae, Galla Chinensis, Herba Scutellariae Barbatae, Flos Lonicerae, Semen Cassiae, Cortex Lycii, Rhizoma Phragmitis, Folium Ginseng, Herba Houttuyniae, Herba Patriniae, Herba Violae, Rhizoma Paridis, Herba Taraxaci, Caulis et Folium cayratiae trifoliae, Herba Lysimachiae, Polyporus, Herba Agrimoniae, Folium Callicarpae Formosanae, charred Petiolus Trachycarpi, Radix Notoginseng.
(2) Radix Scutellariae section
By the Radix Scutellariae cutting taken, removing impurity, puts in boiling water and boils 10 minutes, takes out, braised through, and shave is dry; Or steam half an hour, and take out, shave, dry, note avoiding tanning by the sun.
(3) Semen Cassiae parch
By the Semen Cassiae taken, put in pot, frying with slow fire has fragrance to micro-, takes out, cools.
(4) pulverize
Various raw material super micron mill is ground into 300 object powder respectively.
(5) mix
By the powder of various raw materials obtained, according to the weight ratio mix homogeneously of embodiment 4,5 or 6, this tcm product obtained.
Embodiment 12
The preparation method of Chinese medicine described in embodiment 7-9, comprises the following steps:
(1) get the raw materials ready: prepare following crude drug: Herba Andrographis, Flos Lonicerae, Radix Scutellariae, Galla Chinensis, Herba Kalimeridis grass, field thistle, Flos Sophorae, Flos Hibisci, Flos Campsis, Flos Celosiae Cristatae, Herba Artemisiae Annuae, Radix Scrophulariae, Radix Rehmanniae, Radix et Caulis Opuntiae Dillenii, Exocarpium Benincasae, Pollen Typhae, Radix Rubiae, Crinis Carbonisatus, Folium Mori, Folium Lycii, Flos Chrysanthemi, Herba Dendranthematis indici, Spica Prunellae.
(2) Radix Scutellariae section
By the Radix Scutellariae cutting taken, removing impurity, puts in boiling water and boils 10 minutes, takes out, braised through, and shave is dry; Or steam half an hour, and take out, shave, dry, note avoiding tanning by the sun.
(3) pulverize
Various raw material super micron mill is ground into 300 object powder respectively.
(4) mix
By the powder of various raw materials obtained, according to the weight ratio mix homogeneously of embodiment 7,8 or 9, this tcm product obtained.
Embodiment 13
Treatment case:
Apostichopus japonicus culture field, Lang Ya town one, Qingdao Jiaonan City, Shandong Province on the 5th March in 2014:
There is the Radix Morinae Bulleyanae of 3 canopy specification 1.5 ~ 2.0g, start morbidity from mid-February.
Treating initial infection disease ginseng have phenomenon of shaking the head more, oral area occurs that locality infects, and show as tentacle black turbid, irritant reaction is blunt to external world, oral area swelling, can not shrink and close, then most of Radix Morinae Bulleyanae there will be arrange dirty phenomenon;
Mid-term infect Radix Morinae Bulleyanae health shrink, stiff, body colour is dimmed, but clavus bleach, bald blunt, first there is small size ulcer in food portion, forms little blue and white speckle; The focus infecting disease ginseng in latter stage expands, ulcer place increases, and epidermis large area is rotted, and finally causes Radix Morinae Bulleyanae dead, dissolves the colloid for nasal mucus shape.Be diagnosed as Radix Morinae Bulleyanae " skin ulcerative syndrome ".
Therapeutic Method: the tcm product adopting embodiment 1-3 formula obtained respectively to 3 canopies:
(1) 1# canopy: the tcm product adopting the formula of embodiment 1 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(2) 2# canopy: the tcm product adopting the formula of embodiment 2 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(3) 3# canopy: the tcm product adopting the formula of embodiment 3 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
Therapeutic outcome:
Mix bait by 0.5 ‰ additions of body weight to throw something and feed 5 days, within 7 days, medication is after 5 days again at interval, and above symptom disappears completely, and cure rate is respectively 96.3%, 95.1%, 95.3%, and without recurrence, relapse rate is 0.
Can find out thus, the formula of embodiment 1-3, the cure rate of embodiment 1 is best, is preferred embodiment.
Embodiment 14
Treatment case:
Apostichopus japonicus culture field, great Yang Jia town one, Longkou City, Weihai, Shandong Province on the 12nd April in 2014: the Radix Morinae Bulleyanae having 3 pond specification 4.0 ~ 7.5g, from starting morbidity by the end of March, the disease ginseng for the treatment of initial infection has phenomenon of shaking the head more, oral area swelling, can not to shrink and closed, irritant reaction is blunt to external world, and most of Radix Morinae Bulleyanae there will be the dirty phenomenon of row then; Mid-term infect Radix Morinae Bulleyanae health shrink, stiff, poor adhesive force, body colour is dimmed, but clavus bleach, bald blunt, first there is small size ulcer in clavus, forms little blue and white speckle; The focus infecting disease ginseng in latter stage expands, ulcer place increases, and epidermis large area is rotted, and finally causes disease to be joined dead, dissolves the colloid for nasal mucus shape.Be diagnosed as Radix Morinae Bulleyanae " skin ulcerative syndrome ".
Therapeutic Method:
To 3 canopies adopt respectively embodiment 4-6 formula built in tcm product
(1) tcm product adopting the formula of embodiment 4 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(2) tcm product adopting the formula of embodiment 5 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(3) tcm product adopting the formula of embodiment 6 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
Therapeutic outcome:
Mix bait by 0.5 ‰ additions of body weight to throw something and feed 5 days, within 7 days, medication is after 5 days again at interval, and above symptom disappears completely, and cure rate is respectively 97.3%, 95.8%, 95.9%, and without recurrence, relapse rate is 0.
Can find out thus, the formula of embodiment 4-6, the cure rate of embodiment 4 is best, is preferred embodiment.
Embodiment 12
Treatment case:
Apostichopus japonicus culture field, Tian Heng town one, Qingdao Jimo City, Shandong Province on the 5th June in 2014: the Radix Morinae Bulleyanae having 3 canopy specification 11.5 ~ 18.0g, morbidity is started from mid-May, the disease ginseng for the treatment of initial infection has phenomenon of shaking the head more, oral area occurs that locality infects, show as tentacle black turbid, irritant reaction is blunt to external world, oral area swelling, can not to shrink and closed, and most of Radix Morinae Bulleyanae there will be the dirty phenomenon of row then; The Radix Morinae Bulleyanae health atrophy, stiff that mid-term infects, the dimmed blackening of body colour, but clavus bleach, bald blunt, first there is small size ulcer in food portion, forms little blue and white speckle; The focus infecting sick ginseng in latter stage expands, clavus flattens, and ulcer place increases, and whole body epidermis large area is rotted, and finally causes disease to join dissolving dead.Be diagnosed as Radix Morinae Bulleyanae " skin ulcerative syndrome ".
Therapeutic Method:
To 3 canopies adopt respectively embodiment 7-9 formula built in tcm product
(1) tcm product adopting the formula of embodiment 7 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(2) tcm product adopting the formula of embodiment 8 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
(3) tcm product adopting the formula of embodiment 9 to make, mixes bait by 0.5 ‰ additions of Radix Morinae Bulleyanae body weight and throws something and feeds 5 ~ 7 days, and interval 7 days use again, uses twice continuously.
Therapeutic outcome:
Mix bait by 0.5 ‰ additions of body weight to throw something and feed 5 days, within 7 days, medication is after 5 days again at interval, and above symptom disappears completely, and cure rate is respectively 97.8%, 95.8%, 95.7%, and without recurrence, relapse rate is 0.
Can find out thus, the formula of embodiment 7-9, the cure rate of embodiment 7 is best, is preferred embodiment.
Embodiment 13
Mix bait to the Radix Morinae Bulleyanae of normal growth by 0.05 ‰ addition of body weight to throw something and feed 5 days, interval 15 days medication 5 days again, content (butt) Comparative result not adding part nutrient substance in the Radix Morinae Bulleyanae of product cultivating of the present invention with control sample is as follows:
(1) add the Radix Morinae Bulleyanae that product of the present invention is fed, in aminoacid composition, TEAA improves 5%.
(2) add the Radix Morinae Bulleyanae that product of the present invention is fed, Fresh ear field total amount and drug effect total amino acid content improve 6%.
Can find out thus, the Radix Morinae Bulleyanae of adding product of the present invention nursing has higher nutritive value.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that a cure rate is high, it is characterized in that: be grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Hedyotidis Diffusae 3 parts, Herba Taraxaci 5 parts, Herba Violae 4 parts, Herba Patriniae 3 parts, Rhizoma Smilacis Glabrae 2 parts, Flos Chrysanthemi Indici 5 parts, Radix Sophorae Tonkinensis 2 parts, Radix Sophorae Flavescentis 3 parts, Radix Semiaquilegiae 4 parts, Semen Plantaginis 3 parts, Pericarpium Arecae 4 parts, Medulla Junci 4 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 2 parts, Nodus Nelumbinis Rhizomatis 3 parts, Corium Erinacei Seu Hemiechianus 2 parts.
2. a Chinese medicine preparation for the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, is characterized in that: be grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Herba Scutellariae Barbatae 6 parts, Semen Cassiae 4 parts, Cortex Lycii 3 parts, Rhizoma Phragmitis 5 parts, Folium Ginseng 6 parts, Herba Houttuyniae 4 parts, Herba Patriniae 5 parts, Herba Violae 6 parts, Rhizoma Paridis 3 parts, Herba Taraxaci 5 parts, Caulis et Folium cayratiae trifoliae 6 parts, Herba Lysimachiae 4 parts, Polyporus 5 parts, Herba Agrimoniae 6 parts, Folium Callicarpae Formosanae 5 parts, charred Petiolus Trachycarpi 4 parts, Radix Notoginseng 5 parts.
3. a Chinese medicine preparation for the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, is characterized in that: be grouped into by the one-tenth of following weight parts: Herba Andrographis 25-35 part, Flos Lonicerae 15-25 part, Radix Scutellariae 15-25 part, Galla Chinensis 25-35 part, Herba Kalimeridis grass 4 parts, field thistle 5 parts, 3 parts, Flos Sophorae, Flos Hibisci 5 parts, Flos Campsis 4 parts, Flos Celosiae Cristatae 6 parts, Herba Artemisiae Annuae 3 parts, Radix Scrophulariae 1 part, Radix Rehmanniae 2 parts, Radix et Caulis Opuntiae Dillenii 6 parts, Exocarpium Benincasae 5 parts, Pollen Typhae 3 parts, 6 parts, Radix Rubiae, Crinis Carbonisatus 2 parts, 5 parts, Folium Mori, Folium Lycii 4 parts, Flos Chrysanthemi 4 parts, 4 parts, Herba Dendranthematis indici, Spica Prunellae 5 parts.
4. a preparation method for the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that cure rate is high, is characterized in that: comprise the following steps: get the raw materials ready, Radix Scutellariae is cut into slices, pulverize and mixing.
5. a kind of preparation method for the treatment of the Chinese medicine preparation of Radix Morinae Bulleyanae skin ulcerative syndrome according to claim 4, is characterized in that: described Radix Scutellariae slicing step, and by the Radix Scutellariae cutting taken, removing impurity, puts in boiling water and boil 10 minutes, takes out, braised through, and shave is dry.
6. the preparation method of the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that a kind of cure rate according to claim 4 is high, it is characterized in that: also comprise Nodus Nelumbinis Rhizomatis parch to black step, fry burned black to appearance by Nodus Nelumbinis Rhizomatis, the inside is sallow, taking-up is put in iron pan or porcelain dish, spreads out cold rear stand-by.
7. the preparation method of the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that a kind of cure rate according to claim 4 is high, is characterized in that: described pulverising step, and various raw material super micron mill is ground into 300 object powder respectively.
8. the preparation method of the Chinese medicine preparation of the Radix Morinae Bulleyanae skin ulcerative syndrome that a kind of cure rate according to claim 4 is high, is characterized in that: described blend step, by the powder of various raw materials obtained, by weight mix homogeneously, and this tcm product obtained.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101623315A (en) * | 2009-07-28 | 2010-01-13 | 中国水产科学研究院黄海水产研究所 | Antibacterial immune double-effect compound Chinese herb for skin ulcerative syndrome of apostichopus japonicus |
| CN102961660A (en) * | 2012-12-14 | 2013-03-13 | 张�杰 | Chinese herbal medicine for treating fish diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623315A (en) * | 2009-07-28 | 2010-01-13 | 中国水产科学研究院黄海水产研究所 | Antibacterial immune double-effect compound Chinese herb for skin ulcerative syndrome of apostichopus japonicus |
| CN102961660A (en) * | 2012-12-14 | 2013-03-13 | 张�杰 | Chinese herbal medicine for treating fish diseases |
Non-Patent Citations (1)
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| 侯文久等: "中草药对刺参腐皮综合症病原菌的抑菌试验", 《中国农学通报》 * |
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Inventor after: Wang Yingeng Inventor after: Chen Bingjian Inventor after: Rong Xiaojun Inventor after: Guo Weili Inventor after: Zhang Zheng Inventor after: Liu Yongcai Inventor after: Su Bin Inventor after: Cai Yana Inventor before: Chen Bingjian Inventor before: Li Hengwei Inventor before: Guo Weili Inventor before: Su Bin Inventor before: Cai Yana Inventor before: Guan Lin |
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