CN104812892B - 经修饰的人轮状病毒及其用途 - Google Patents

经修饰的人轮状病毒及其用途 Download PDF

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CN104812892B
CN104812892B CN201380054966.7A CN201380054966A CN104812892B CN 104812892 B CN104812892 B CN 104812892B CN 201380054966 A CN201380054966 A CN 201380054966A CN 104812892 B CN104812892 B CN 104812892B
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vero
protein
trypsin
amino acid
gene
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CN104812892A (zh
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卡尔·柯克伍德
露丝·弗兰塞斯·毕晓普
格雷姆·劳伦斯·巴恩斯
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Murdoch Childrens Research Institute
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    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/765—Reovirus; Rotavirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21004—Trypsin (3.4.21.4)
    • A—HUMAN NECESSITIES
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    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
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CN201380054966.7A 2012-08-27 2013-08-26 经修饰的人轮状病毒及其用途 Active CN104812892B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2012903702 2012-08-27
AU2012903702A AU2012903702A0 (en) 2012-08-27 Modified human rotaviruses and uses therefor
PCT/AU2013/000945 WO2014032082A1 (en) 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor

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CN104812892A CN104812892A (zh) 2015-07-29
CN104812892B true CN104812892B (zh) 2018-07-17

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AU (1) AU2013308377B2 (enExample)
BR (1) BR112015004085A2 (enExample)
CU (1) CU24328B1 (enExample)
IN (1) IN2015DN01342A (enExample)
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GB201900250D0 (en) 2019-01-08 2019-02-27 Ge Healthcare Bio Sciences Ab Method for virus propagation
CN117257928B (zh) * 2023-09-22 2024-12-31 成都迈科康生物科技有限公司 一种冻干口服轮状减毒活疫苗及其制备方法和应用
CN117947096B (zh) * 2024-01-16 2024-08-30 伊诺维康(北京)生物科技有限公司 一种羊轮状病毒重组质粒、反向遗传病毒学拯救系统及其构建方法和应用

Citations (3)

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CN101302500A (zh) * 1999-08-17 2008-11-12 史密丝克莱恩比彻姆生物有限公司 疫苗
CN101489587A (zh) * 2006-05-12 2009-07-22 伯哈拉特生物技术国际有限公司 一种可用作疫苗的组合物
WO2010132561A2 (en) * 2009-05-12 2010-11-18 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention New human rotavirus strains and vaccines

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US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4579945A (en) 1982-04-29 1986-04-01 Ribi Immunochem Research, Inc. Purification of trehalose dimycolates
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
US6056957A (en) 1994-08-04 2000-05-02 Schering Corporation Humanized monoclonal antibodies against human interleukin-5
HK1046860B (en) 1999-08-17 2006-10-06 Smithkline Beecham Biologicals S.A. Method of separating rotavirus variants and live attenuated rotavirus vaccine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101302500A (zh) * 1999-08-17 2008-11-12 史密丝克莱恩比彻姆生物有限公司 疫苗
CN101489587A (zh) * 2006-05-12 2009-07-22 伯哈拉特生物技术国际有限公司 一种可用作疫苗的组合物
WO2010132561A2 (en) * 2009-05-12 2010-11-18 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention New human rotavirus strains and vaccines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
G3P2 rotaviruses causing diarrhoeal disease in neonates differ in VP4, VP7 and NSP4 sequence from G3P2 strains causing asymptomatic neonatal infection;C. D. Kirkwood等;《Arch Virol》;19961231;第141卷;1666页第1段 *
Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites;C.D.Kirkwood等;《Arch Virol》;19961231;第141卷;587-600 *

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US20180346884A1 (en) 2018-12-06
CN104812892A (zh) 2015-07-29
IN2015DN01342A (enExample) 2015-07-03
MX2015002495A (es) 2016-06-30
CU24328B1 (es) 2018-03-13
CU20150019A7 (es) 2015-09-29
NZ631348A (en) 2017-02-24
AU2013308377A1 (en) 2015-02-26
US20150337268A1 (en) 2015-11-26
EP2888355A1 (en) 2015-07-01
AU2013308377B2 (en) 2019-06-06
KR102182186B1 (ko) 2020-11-25
US9969985B2 (en) 2018-05-15
BR112015004085A2 (pt) 2017-08-08
WO2014032082A1 (en) 2014-03-06
KR20150044954A (ko) 2015-04-27
EP2888355A4 (en) 2016-08-10
WO2014032082A8 (en) 2015-04-16
MX370502B (es) 2019-12-16
EP2888355B1 (en) 2020-06-17

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