AU2013308377B2 - Modified human rotaviruses and uses therefor - Google Patents

Modified human rotaviruses and uses therefor Download PDF

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Publication number
AU2013308377B2
AU2013308377B2 AU2013308377A AU2013308377A AU2013308377B2 AU 2013308377 B2 AU2013308377 B2 AU 2013308377B2 AU 2013308377 A AU2013308377 A AU 2013308377A AU 2013308377 A AU2013308377 A AU 2013308377A AU 2013308377 B2 AU2013308377 B2 AU 2013308377B2
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gene
protein
vero
amino acid
human
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AU2013308377A1 (en
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Graeme Laurence Barnes
Ruth Frances Bishop
Carl KIRKWOOD
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Murdoch Childrens Research Institute
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Murdoch Childrens Research Institute
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/765—Reovirus; Rotavirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
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    • A61K2039/525—Virus
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    • C12N2720/12011—Reoviridae
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    • C12N2720/12011—Reoviridae
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12361—Methods of inactivation or attenuation
    • C12N2720/12363—Methods of inactivation or attenuation by chemical treatment
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    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12361—Methods of inactivation or attenuation
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
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  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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AU2013308377A 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor Active AU2013308377B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013308377A AU2013308377B2 (en) 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2012903702 2012-08-27
AU2012903702A AU2012903702A0 (en) 2012-08-27 Modified human rotaviruses and uses therefor
AU2013308377A AU2013308377B2 (en) 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor
PCT/AU2013/000945 WO2014032082A1 (en) 2012-08-27 2013-08-26 Modified human rotaviruses and uses therefor

Publications (2)

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AU2013308377A1 AU2013308377A1 (en) 2015-02-26
AU2013308377B2 true AU2013308377B2 (en) 2019-06-06

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US (2) US9969985B2 (enExample)
EP (1) EP2888355B1 (enExample)
KR (1) KR102182186B1 (enExample)
CN (1) CN104812892B (enExample)
AU (1) AU2013308377B2 (enExample)
BR (1) BR112015004085A2 (enExample)
CU (1) CU24328B1 (enExample)
IN (1) IN2015DN01342A (enExample)
MX (1) MX370502B (enExample)
NZ (1) NZ631348A (enExample)
WO (1) WO2014032082A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201900250D0 (en) 2019-01-08 2019-02-27 Ge Healthcare Bio Sciences Ab Method for virus propagation
CN117257928B (zh) * 2023-09-22 2024-12-31 成都迈科康生物科技有限公司 一种冻干口服轮状减毒活疫苗及其制备方法和应用
CN117947096B (zh) * 2024-01-16 2024-08-30 伊诺维康(北京)生物科技有限公司 一种羊轮状病毒重组质粒、反向遗传病毒学拯救系统及其构建方法和应用

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US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4579945A (en) 1982-04-29 1986-04-01 Ribi Immunochem Research, Inc. Purification of trehalose dimycolates
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
US6056957A (en) 1994-08-04 2000-05-02 Schering Corporation Humanized monoclonal antibodies against human interleukin-5
HK1046860B (en) 1999-08-17 2006-10-06 Smithkline Beecham Biologicals S.A. Method of separating rotavirus variants and live attenuated rotavirus vaccine
GB9919468D0 (en) * 1999-08-17 1999-10-20 Smithkline Beecham Biolog Vaccine
BRPI0711608B8 (pt) * 2006-05-12 2021-05-25 Bharat Biotech Int Ltd composição liofilizada, uso de antígeno viral, método de tratamento ou prevenção de vírus associado, método de adaptação de um vírus de uma linhagem celular adequada
CN102695522B (zh) * 2009-05-12 2016-10-19 美国政府(由卫生和人类服务部、疾病控制和预防中心的部长所代表) 新的人轮状病毒株和疫苗

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KIRKWOOD C D ET AL, "Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites", ARCHIVES OF VIROLOGY, (1996), vol. 141, no. 3-4, ISSN 0304-8608, pages 587 - 600 *

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US20180346884A1 (en) 2018-12-06
CN104812892A (zh) 2015-07-29
IN2015DN01342A (enExample) 2015-07-03
MX2015002495A (es) 2016-06-30
CU24328B1 (es) 2018-03-13
CU20150019A7 (es) 2015-09-29
NZ631348A (en) 2017-02-24
AU2013308377A1 (en) 2015-02-26
US20150337268A1 (en) 2015-11-26
EP2888355A1 (en) 2015-07-01
KR102182186B1 (ko) 2020-11-25
US9969985B2 (en) 2018-05-15
BR112015004085A2 (pt) 2017-08-08
WO2014032082A1 (en) 2014-03-06
KR20150044954A (ko) 2015-04-27
EP2888355A4 (en) 2016-08-10
WO2014032082A8 (en) 2015-04-16
CN104812892B (zh) 2018-07-17
MX370502B (es) 2019-12-16
EP2888355B1 (en) 2020-06-17

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