CN104800707A - Traditional Chinese medicine composition for treating stomach cancer and restraining cancer cell spreading and preparation method - Google Patents
Traditional Chinese medicine composition for treating stomach cancer and restraining cancer cell spreading and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating stomach cancer and restraining cancer cell spreading. The traditional Chinese medicine composition is prepared by taking the main raw materials by weight part: 2 to 3 parts of centipede, 6 to 12 parts of lycopene, 15 to 20 parts of pearl powder, 4 to 10 parts of hericium erinaceus, 5 to 15 parts of trigone, 2 to 9 parts of scorpio, 1 to 5 parts of galium aparine, 1 to 5 parts of rhizoma corydalis and 3 to 8 parts of indigo naturalis. The invention aims to provide the traditional Chinese medicine composition for treating stomach cancer and restraining cancer cell spreading, has the characteristics of easiness in operation and obvious curative effect, and is low in cost.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially a kind of Chinese medicine composition and method for making for the treatment of the diffusion of gastric cancer anticancer.The invention belongs to traditional Chinese medicine field.
Background technology
Gastric cancer is one of cancer that in worldwide, sickness rate is the highest.Annual newly-increased 900,000 patients with gastric cancer in the whole world, have 700,000 people to die from gastric cancer simultaneously every year.The sickness rate of gastric cancer significantly raises along with the increase at age, and the peak age of morbidity was at 50 years old ~ 80 years old.Wherein, the sickness rate of male is 1.5 ~ 2.5 times of women, and mortality rate is only second to pulmonary carcinoma occupies second.Meanwhile, the incidence gastric cancer rate of women and mortality rate have the trend of rising.China is the district occurred frequently of gastric cancer, and gastric cancer annual loading and mortality rate are all more than 2 times of world average level.Second National coroner's inquest result according to sanitation Ministry tissue shows, and the mortality rate of Chinese gastric cancer accounts for all because of number of cancer deaths's 23.2%, close to 1/4th.
The symptom of gastric cancer: 1. early gastric cancer more than 70% non-evident sympton, along with the development of the state of an illness, nonspecific, to exactly like gastritis or gastric ulcer symptom can be engendered, comprise the glutted discomfort of epigastrium or dull pain, pantothenic acid, belch, feel sick, occasionally have vomiting, loss of appetite, melena etc.2. advanced gastric carcinoma symptom is shown in gastric area pain, is often gnawing property, with feed without obvious relation, also has similar peptic ulcer pain, can alleviate after feed.Epigastrium feeling of repletion, sense of heaviness, anorexia, stomachache, nausea,vomiting,diarrhea, become thin, anemia, edema, heating etc.Carcinoma of gastric cardia main manifestations is uncomfortable under xiphoid-process, pain or retrosternal pain, companion's dysphagia sense or dysphagia; At the bottom of stomach and the normal non-evident sympton of cardia inferior segment cancer, just arouse attention until the huge and diabrosis that necroses of tumor causes during upper gastrointestinal hemorrhage, or begin to give attention because of tumor-infiltrated extending to after cardia causes dysphagia; Body of stomach cancer is more common with intumescent, and pain discomfort occurs more late; Gastric antrum lesser curvature side is the most common with ulcer type cancer, therefore the symptom of epigastrium pain occurs comparatively early, when tumor prolong and pyloric ostium time, then can to cause nausea, the pyloric obstruction symptom such as vomiting.Cancerous protuberance diffusion transfer can cause the transfer of ascites, hepatomegaly, jaundice and lung, brain, the heart, prostate, ovary, bone marrow etc. and occur corresponding symptom.
Now for the treatment of gastric cancer, doctor trained in Western medicine adopts operative treatment, radiotherapy or chemotherapy three one usually, or the method for together treating.Operative treatment: generally include radical surgery, palliative operation, detecting property is performed the operation.Namely take operation as means complete removal of lesions or cut-out focus, reach the method for curing or controlling cancer.Radiotherapy: be called for short radiotherapy, be utilize high-energy electromagnetic radiation line to act on life entity, biomolecular structure is changed, reach a kind of Therapeutic Method of destruction of cancer cells object.Radiation can Therapeutic cancer be because cancerous cell is responsive to lonizing radiation.The lonizing radiation applied clinically at present have x-ray to treat and r line treats two kinds.Chemotherapy: chemotherapy takes medicine intravascular to whole body, has impact to health all cells.This therapy is sometimes also referred to as " born of the same parents poison therapy ", because medicine used is all harmful, or even band toxicity, whether cells in vivo, no matter malignant cell, be all damaged.No matter be adopt operative treatment, radiotherapy or adopt chemotherapy, all great burden caused to the health of patient, and costly, sufferer is born painful large.Along with the development of Chinese Chinese medicine, in the diffusion for the treatment of gastric cancer anticancer, it is little that people appreciate treatment by Chinese herbs gastric cancer anticancer diffusion side effect gradually, bear painful little advantage, and Chinese traditional treatment great attention to whole idea, pay attention to comprehensive control, pay attention to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, therapeutic effect demonstrates the advantage for the treatment of by Chinese herbs gastric cancer anticancer diffusion more.Chinese medicine has the special efficacy of the diffusion for the treatment of gastric cancer anticancer, improving eyesight, and persistent, treating both the principal and secondary aspects of a disease, has no side effect and efficacy consolidation, not easily to recur.
Summary of the invention
For the present situation of existing gastric cancer anticancer diffusion, an object of the present invention is the Chinese medicine composition providing the diffusion for the treatment of gastric cancer anticancer, has feature easy to operate, evident in efficacy, with low cost.Another object is just to provide the preparation method of above-mentioned Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from: Scolopendra 2-3 part, lycopene 6-12 part, Margarita powder 15-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-10 part, Rhizoma Sparganii 5-15 part, Scorpio 2-9 part, Herba Galii Teneri 1-5 part, Rhizoma Corydalis 1-5 part, Indigo Naturalis 3-8 part.
The Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, preferred version is, take off the primary raw material stating weight proportion to be prepared from: Scolopendra 2.3-2.8 part, lycopene 7-11 part, Margarita powder 16-19 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 5-8 part, Rhizoma Sparganii 7-13 part, Scorpio 4-7 part, Herba Galii Teneri 2-4 part, Rhizoma Corydalis 2-4 part, Indigo Naturalis 5-7 part.
The Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, preferred version is, takes off the primary raw material stating weight proportion and is prepared from: Scolopendra 2.5 parts, lycopene 9 parts, Margarita powder 18 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 6 parts, Rhizoma Sparganii 10 parts, Scorpio 5 parts, Herba Galii Teneri 3 parts, Rhizoma Corydalis 3 parts, Indigo Naturalis 6 parts.
The preparation method of above-mentioned Chinese medicine composition, is characterized in that, step is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10-20 hour, is placed on food steamer, and big fire decocts to boiling, 10-20 minute is decocted at little fire, taking-up is placed in microwave oven, fries 2-6 minute, and grinding to form smalls, to cross 80-120 mesh sieve stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add Rhizoma Corydalis weight 2-6 clear water doubly, decoct 20-30 minute, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 3-7 to be mixed minute; cease fire, be placed in 20-30 DEG C of standing 5-10 hour, get supernatant and bottle and obtain compositions.
Above-mentioned preparation method, step (2) is placed in crock, slightly stewing 13-18 hour (preferred, be placed in crock, slightly stewing 15 hours).
Above-mentioned preparation method, step (2) big fire decocts to boiling, decocts 13-18 minute, take out and be placed in microwave oven at little fire, fries 3-5 minute (preferred, big fire decocts to boiling, decocts 15 minutes, take out and be placed in microwave oven, fry 4 minutes at little fire).
Above-mentioned preparation method, step (3) adds Rhizoma Corydalis weight 3-5 clear water doubly (preferred, to add the clear water of Rhizoma Corydalis weight 4 times).
Above-mentioned preparation method, step (3) decocts 23-28 minute, filters (preferred, to decoct 25 minutes, filter).
Above-mentioned preparation method, step (4) decocts and stirs with large ferrum spoon, after 4-6 to be mixed minute (preferred, to decoct while stir, after 5 minutes to be mixed with large ferrum spoon).
Above-mentioned preparation method, step (4) is placed in 23-28 DEG C of standing 6-9 hour (preferred, to be placed in 25 DEG C and to leave standstill 7.5 hours).
Using method: for making the present invention reach optimum therapeuticing effect, before breakfast, lunch and dinner, half an hour takes, 3 times on the one, each 10ml.
The pharmacological effect of each crude drug is respectively:
Scolopendra: nature and flavor: pungent, temperature; Poisonous.Gui Jing: return Liver Channel.Effect: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.
Cure mainly: for infantile convulsion, tic spasm, middle air port is drunk, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Lycopene: the above-mentioned biological characteristics of lycopene determines it to be had antioxidation, mutation inhibiting, reduction nucleic acid damaging, reduce the plurality of health care functions such as cardiovascular disease and prophylaxis of cancer, lycopene has prevention and prohibition function of tumor, is because its antioxidation on the one hand; Be on the other hand that lycopene can block histiocyte gene mutation process occurs under the effect of extraneous mutagenic agent, this is one of important mechanisms of generating of tumor.Experiment finds, lycopene can affect mammary gland, lung and the S phase in uterine cancer cells cycle; Lycopene affects the growth of cell by the transformation stage of Gl to S in the T suppression cell cycle; Lycopene passes through the formation that can suppress the oxidation of LDL-C and decoct the heterocyclic amine produced in the browning reaction of barbecue, fish, thus effectively suppresses carcinogenic generation and induced tumor.Research shows, lycopene all has certain inhibitory action to digestive tract cancer, cervical cancer, breast carcinoma, skin carcinoma, bladder cancer etc.
Margarita powder: the Organic substance [3] in Margarita is containing 17 seed amino acids such as Aspartic Acid, threonine, serine, glutamic acid, glycine, alanine, cystine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, histidine, arginine, proline.In addition, also containing 30 various trace elements, taurine, abundant vitamin, peptide class.
To calm the nerves arresting convulsion, heat clearing away YIN nourishing, improving eyesight, removing toxic substances.1. relieving palpitation arresting convulsion, is applicable to palpitation with fear palpitation with a distress feeling, epilepsy infantile convulsion.2. liver heat removing is except nebula improving eyesight, with controlling the ophthalmic diseases such as conjunctival congestion and swelling pain, pterygium, and many externals.3. restrain granulation promoting, be applicable to that throat rots, aphtha of the mouth and tongue, ulcer do not close up for a long time, should external, tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, removing toxic substances and promoting granulation.Control palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, and the raw cataracta of order, skin infection does not close up for a long time.
Hericium erinaceus (Bull. Ex Fr.) Pers.: Hericium erinaceus (Bull. Ex Fr.) Pers.: base is former: be the sporophore of hedgehog fungus section Hericium fungus Hericium erinaceus (Bull. Ex Fr.) Pers., Hydnum.Composition: containing Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone A, B, C, D, E, F, G, H in Hericium erinaceus, Hericium erinaceus (Bull. Ex Fr.) Pers. alkali etc.Dry sporophore is containing protein, lipid, fiber and glucosan.Also containing sterols: ergosterol etc.Mycelium culture contains Hericium erinaceus (Bull. Ex Fr.) Pers. pyrone A, B etc.The property of medicine: " national Chinese herbal medicine compilation ": " sweet, flat." function cures mainly: strengthening the spleen and nourishing the stomach, calms the nerves, anticancer.Cure mainly body void weak, dyspepsia, insomnia, gastroduodenal ulcer, chronic gastritis, digestive tract tumor.
Rhizoma Sparganii: pungent, bitter is flat.Gui Jing returns liver, spleen channel, the circulation of qi promoting of effect removing blood stasis, removing food stagnancy pain relieving.Cure mainly for lump in the abdomen mass in the abdomen, dysmenorrhea, blood stasis amenorrhea, obstruction of qi in the chest and cardialgia, food stagnation distending pain.
Scorpio: pungent, flat.Gui Jing returns Liver Channel.Effect endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.Cure mainly for liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air port, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Herba Galii Teneri: have another name called saw grass, draw rattan, fly upward rattan, the herb of taste Rubiaceae clivers Herba Galii Teneri or thick Ye Lala rattan.The property of medicine: herb is very thin, easily broken, the grayish green or green and brown color in surface, feeble QI, acrid in the mouth, bitter in the mouth, cold nature.Composition: Herba Galii Teneri aerial parts is containing alkaloid, and fruit contains Fructus Hordei Germinatus amine, jaligonic acid etc.; Thick Ye Lala rattan aerial parts contains asperuloside, vitamin C.Find according to modern pharmacological research, this medical instrument has antibacterial, anticancer, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, reducing swelling and alleviating pain effect, for swollen ulcer drug, and appendicitis, cold, fever, hematuria etc.
Rhizoma Corydalis: Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.There is promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Indigo Naturalis: have another name called Concha Meretricis Seu Cyclinae powder, indigo-blue flower, for the leaf of Acanthaceae Acanthaceous indigo platymiscium Acanthaceous indigo, Polygonaceae arsesmart polygonum tinctorium ait., pulse family anil Folium et Caulis Indigoferae Tinctoriae, Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.The property of medicine: this product is navy blue powder, body is light, and easily fly upward, micro-have careless stink smell, salty in the mouth, cold in nature.Composition: its main component has indirubin, indigo.Find according to modern pharmacological research, this medical instrument has effect of antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing away heat and cooling blood, removing toxic substances, and for the malicious macule of temperature, laryngopharynx swelling and pain, spits blood, epistaxis, the symptoms such as spitting of blood.
Compared with prior art, technical advantage of the present invention is embodied in:
1, the present invention's medical material used does not have toxicity, and the health mechanism for sufferer can not cause damage, and audient crowd is wide, and applicable child and old people take.
2, bright the used medical material relative inexpensiveness of this law, compared with prior art the bright obtained Chinese medicine composition cost of this law is cheaper.
3, therapeutic effect of the present invention is compared to prior art, and therapeutic effect is more obvious, and treatment cycle is short, does not have obvious sequela, can life-time service.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 2 parts, lycopene 6 parts, Margarita powder 15 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 4 parts, Rhizoma Sparganii 5 parts, Scorpio 2 parts, Herba Galii Teneri 1 part, Rhizoma Corydalis 1 part, Indigo Naturalis 3 parts.
The Chinese medicine composition preparation process for the treatment of gastric cancer anticancer diffusion is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10 hours, be placed on food steamer, big fire decocts to boiling, decoct 10 minutes at little fire, taking-up is placed in microwave oven, fries 2 minutes, and grinding to form smalls, to cross 80 mesh sieves stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add the clear water of Rhizoma Corydalis weight 2 times, decoct 20 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 3 minutes to be mixed; cease fire, be placed in 20 DEG C and leave standstill 5 hours, get supernatant and bottle and obtain compositions.
model case onepoplar XX, man, 44 years old, in May, 2013 just started to swallow pain obstinate, after with the symptom of deep coughs, spitting of blood, the obvious enlargement of throat.Intermediate gastric carcinoma is diagnosed as through examination in hospital.
Take embodiment 1 resulting composition, use traditional Chinese medicine composition for treating of the present invention 10 days, spitting of blood symptom alleviates, and pharyngeal pain is alleviated to some extent; Use traditional Chinese medicine composition for treating of the present invention 2 months, laryngeal neoplasm reduces; Use traditional Chinese medicine composition for treating of the present invention 4 months, after hospital's check, find tumor atrophy, in continuing at present to take.
embodiment 2the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Scolopendra 3 parts, lycopene 12 parts, Margarita powder 20 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 10 parts, Rhizoma Sparganii 15 parts, Scorpio 9 parts, Herba Galii Teneri 5 parts, Rhizoma Corydalis 5 parts, Indigo Naturalis 8 parts.
The Chinese medicine composition preparation process for the treatment of gastric cancer anticancer diffusion is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 20 hours, be placed on food steamer, big fire decocts to boiling, decoct 20 minutes at little fire, taking-up is placed in microwave oven, fries 6 minutes, and grinding to form smalls, to cross 120 mesh sieves stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add the clear water of Rhizoma Corydalis weight 4 times, decoct 30 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 7 minutes to be mixed; cease fire, be placed in 30 DEG C and leave standstill 10 hours, get supernatant and bottle and obtain compositions.
embodiment 3the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Scolopendra 2.3 parts, lycopene 7 parts, Margarita powder 16 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Rhizoma Sparganii 7 parts, Scorpio 4 parts, Herba Galii Teneri 2 parts, Rhizoma Corydalis 2 parts, Indigo Naturalis 5 parts.
The Chinese medicine composition preparation process for the treatment of gastric cancer anticancer diffusion is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 13 hours, be placed on food steamer, big fire decocts to boiling, decoct 13 minutes at little fire, taking-up is placed in microwave oven, fries 3 minutes, and grinding to form smalls, to cross 90 mesh sieves stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add the clear water of Rhizoma Corydalis weight 2.5 times, decoct 23 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 4 minutes to be mixed; cease fire, be placed in 23 DEG C and leave standstill 6 hours, get supernatant and bottle and obtain compositions.
typical case two: Feng XX, man, 46 years old, construction site workman, the autumn in 2012 started to occur difficulty of swallowing of eating, and weight loss, intermittent stomach pain, with serious vomiting, goes hospital diagnosis to be early gastric cancer.
Take embodiment 3 resulting composition, treat 7 days, symptoms of emesis alleviates, and pain has very large alleviation; Use traditional Chinese medicine composition for treating of the present invention 2 months, function of deglutition recovers completely, obviously diminishes through examination in hospital tumor.Use traditional Chinese medicine composition for treating of the present invention 5 months, tumor disappearance, so far without recurrence.
embodiment 4the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from (getting 25g for every part): Scolopendra 2.8 parts, lycopene 11 parts, Margarita powder 19 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 parts, Rhizoma Sparganii 13 parts, Scorpio 7 parts, Herba Galii Teneri 4 parts, Rhizoma Corydalis 4 parts, Indigo Naturalis 7 parts.
The Chinese medicine composition preparation process for the treatment of gastric cancer anticancer diffusion is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 18 hours, be placed on food steamer, big fire decocts to boiling, decoct 18 minutes at little fire, taking-up is placed in microwave oven, fries 5 minutes, and grinding to form smalls, to cross 110 mesh sieves stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add the clear water of Rhizoma Corydalis weight 3.5 times, decoct 28 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 6 minutes to be mixed; cease fire, be placed in 28 DEG C and leave standstill 9 hours, get supernatant and bottle and obtain compositions.
embodiment 5the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Scolopendra 2.5 parts, lycopene 9 parts, Margarita powder 18 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 6 parts, Rhizoma Sparganii 10 parts, Scorpio 5 parts, Herba Galii Teneri 3 parts, Rhizoma Corydalis 3 parts, Indigo Naturalis 6 parts.
The Chinese medicine composition preparation process for the treatment of gastric cancer anticancer diffusion is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 15 hours, be placed on food steamer, big fire decocts to boiling, decoct 15 minutes at little fire, taking-up is placed in microwave oven, fries 2-64 minute, and grinding to form smalls, to cross 100 mesh sieves stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add the clear water of Rhizoma Corydalis weight 3 times, decoct 25 minutes, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 5 minutes to be mixed; cease fire, be placed in 25 DEG C and leave standstill 7.5 hours, get supernatant and bottle and obtain compositions.
test example 1:the clinical practice of the Chinese medicine composition of embodiment 5 gained treatment gastric cancer anticancer diffusion: in January ,-2015 in July, 2013, 400 routine patients are screened in 5 hospitals, max age 68 years old, minimal ages 38 years old, all suffer from because of the diffusion of gastric cancer anticancer, sufferer is divided into two groups at random, experimental group 200 people, matched group 200 people, experimental group uses the Chinese medicine composition obtained by this enforcement 5, matched group uses other medicines, observe 6 months time limits, test and the symptom of patient was comprehensively checked in first 1 week, inquiry patient body situation and impression is regularly checked during experiment, and make a record.Effective: malaise symptoms alleviates or partial disappearance.Cure: malaise symptoms disappears, and without recurrence.Invalid: malaise symptoms is unchanged or recur.Result is as shown in the table:
Prove through clinical trial, compared with the medicine using Chinese medicine composition of the present invention and other treatment gastric cancer anticancer to spread, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while the diffusion for the treatment of gastric cancer anticancer, can alleviate and spread the pain brought, the symptom such as unable by gastric cancer anticancer.Prove through clinical trial, Chinese medicine composition effective percentage of the present invention is 99%.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat the Chinese medicine composition of gastric cancer anticancer diffusion, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 2-3 part, lycopene 6-12 part, Margarita powder 15-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-10 part, Rhizoma Sparganii 5-15 part, Scorpio 2-9 part, Herba Galii Teneri 1-5 part, Rhizoma Corydalis 1-5 part, Indigo Naturalis 3-8 part.
2. the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 2.3-2.8 part, lycopene 7-11 part, Margarita powder 16-19 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 5-8 part, Rhizoma Sparganii 7-13 part, Scorpio 4-7 part, Herba Galii Teneri 2-4 part, Rhizoma Corydalis 2-4 part, Indigo Naturalis 5-7 part.
3. the Chinese medicine composition for the treatment of gastric cancer anticancer diffusion according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 2.5 parts, lycopene 9 parts, Margarita powder 18 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 6 parts, Rhizoma Sparganii 10 parts, Scorpio 5 parts, Herba Galii Teneri 3 parts, Rhizoma Corydalis 3 parts, Indigo Naturalis 6 parts.
4. the preparation method of the Chinese medicine composition of the treatment gastric cancer anticancer diffusion according to any one of claim 1-3, is characterized in that: step is as follows:
(1) by Scolopendra, removing impurity, is ground into fine powder, is placed in drying receptacle, and put shady and cool place, airtight preservation is stand-by;
(2) Hericium erinaceus (Bull. Ex Fr.) Pers., Rhizoma Sparganii, Scorpio and Herba Galii Teneri are cleaned, smash to pieces, mix thoroughly with yellow wine, wrap up with plastic sheeting, be placed in crock, slightly stewing 10-20 hour, is placed on food steamer, and big fire decocts to boiling, 10-20 minute is decocted at little fire, taking-up is placed in microwave oven, fries 2-6 minute, and grinding to form smalls, to cross 80-120 mesh sieve stand-by;
(3) be placed in marmite by Rhizoma Corydalis, add Rhizoma Corydalis weight 2-6 clear water doubly, decoct 20-30 minute, filter, filtrate is stand-by;
(4) by step (1)-(3) gains mixing, little fire decocts and add lycopene, Margarita powder and Indigo Naturalis to boiling, decocts and stirs with large ferrum spoon; after 3-7 to be mixed minute; cease fire, be placed in 20-30 DEG C of standing 5-10 hour, get supernatant and bottle and obtain compositions.
5. preparation method according to claim 4, is characterized in that: step (2) is placed in crock, slightly stewing 13-18 hour (preferred, be placed in crock, slightly stewing 15 hours).
6. preparation method according to claim 4, it is characterized in that: step (2) big fire decocts to boiling, 13-18 minute is decocted at little fire, taking-up is placed in microwave oven, (preferred, big fire decocts to boiling, decocts 15 minutes at little fire to fry 3-5 minute, taking-up is placed in microwave oven, fries 4 minutes).
7. preparation method according to claim 4, is characterized in that: step (3) adds Rhizoma Corydalis weight 3-5 clear water doubly (preferred, to add the clear water of Rhizoma Corydalis weight 4 times).
8. preparation method according to claim 4, is characterized in that: step (3) decocts 23-28 minute, filters (preferred, to decoct 25 minutes, filter).
9. preparation method according to claim 4, is characterized in that: step (4) decocts and stirs with large ferrum spoon, after 4-6 to be mixed minute (preferred, to decoct while stir, after 5 minutes to be mixed with large ferrum spoon).
10. preparation method according to claim 4, is characterized in that: step (4) is placed in 23-28 DEG C of standing 6-9 hour (preferred, to be placed in 25 DEG C and to leave standstill 7.5 hours).
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Application publication date: 20150729 |