CN1047863A - 3-酮HMG-CoA还原酶抑制剂 - Google Patents

3-酮HMG-CoA还原酶抑制剂 Download PDF

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Publication number
CN1047863A
CN1047863A CN89106377A CN89106377A CN1047863A CN 1047863 A CN1047863 A CN 1047863A CN 89106377 A CN89106377 A CN 89106377A CN 89106377 A CN89106377 A CN 89106377A CN 1047863 A CN1047863 A CN 1047863A
Authority
CN
China
Prior art keywords
phenyl
daiing
alkyl
substituting group
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN89106377A
Other languages
English (en)
Chinese (zh)
Inventor
亨利·乔舒亚
肯尼思·E·威尔逊
迈克尔·S·许瓦兹
李大智
杰拉尔德·E·斯托克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/363,792 external-priority patent/US4968693A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of CN1047863A publication Critical patent/CN1047863A/zh
Pending legal-status Critical Current

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Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN89106377A 1989-06-09 1989-08-12 3-酮HMG-CoA还原酶抑制剂 Pending CN1047863A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US363.792 1989-06-09
US07/363,792 US4968693A (en) 1988-03-02 1989-06-09 3-keto HMG-COA reductase inhibitors

Publications (1)

Publication Number Publication Date
CN1047863A true CN1047863A (zh) 1990-12-19

Family

ID=23431752

Family Applications (1)

Application Number Title Priority Date Filing Date
CN89106377A Pending CN1047863A (zh) 1989-06-09 1989-08-12 3-酮HMG-CoA还原酶抑制剂

Country Status (14)

Country Link
JP (1) JPH0324033A (ja)
CN (1) CN1047863A (ja)
AU (1) AU618106B2 (ja)
CA (1) CA1328877C (ja)
DK (1) DK330389A (ja)
FI (1) FI893272A (ja)
HU (1) HUT54133A (ja)
IE (1) IE892191L (ja)
IL (1) IL90847A0 (ja)
NO (1) NO892761L (ja)
NZ (1) NZ229806A (ja)
PT (1) PT91204B (ja)
YU (1) YU144589A (ja)
ZA (1) ZA895140B (ja)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668699A (en) * 1985-08-05 1987-05-26 Merck & Co., Inc. Novel HMG-CoA reductase inhibitors
PT85109A (en) * 1986-06-23 1987-07-01 Merck & Co Inc Process for the preparation of hydroxy-tetrahydropyranone derivatives or corresponding ring opened dihydroxy acids which are hmg-coa reductase inhibitors
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents

Also Published As

Publication number Publication date
AU618106B2 (en) 1991-12-12
PT91204A (pt) 1991-02-08
IL90847A0 (en) 1990-02-09
FI893272A (fi) 1990-12-10
ZA895140B (en) 1990-03-28
DK330389A (da) 1990-12-10
JPH0324033A (ja) 1991-02-01
PT91204B (pt) 1995-03-31
NO892761D0 (no) 1989-07-04
FI893272A0 (fi) 1989-07-05
HUT54133A (en) 1991-01-28
NO892761L (no) 1990-12-10
CA1328877C (en) 1994-04-26
DK330389D0 (da) 1989-07-04
IE892191L (en) 1990-12-09
NZ229806A (en) 1991-12-23
AU3783889A (en) 1990-12-13
YU144589A (en) 1990-12-31

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PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication