CN104786237A - Glove device on isolator and glove replacing method - Google Patents

Glove device on isolator and glove replacing method Download PDF

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Publication number
CN104786237A
CN104786237A CN201510187286.3A CN201510187286A CN104786237A CN 104786237 A CN104786237 A CN 104786237A CN 201510187286 A CN201510187286 A CN 201510187286A CN 104786237 A CN104786237 A CN 104786237A
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CN
China
Prior art keywords
gloves
sealing ring
ring
holddown groove
isolator
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Granted
Application number
CN201510187286.3A
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Chinese (zh)
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CN104786237B (en
Inventor
吴岳峰
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SHANGHAI SANJIAN PHARMACEUTICAL EQUIPMENT CO., LTD.
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吴岳峰
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Priority to CN201510187286.3A priority Critical patent/CN104786237B/en
Publication of CN104786237A publication Critical patent/CN104786237A/en
Application granted granted Critical
Publication of CN104786237B publication Critical patent/CN104786237B/en
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Abstract

The invention relates to a glove device on an isolator and a glove replacing method. According to the glove device on the isolator and the glove replacing method, the isolator comprises a box body with a cavity and at least one glove device, and an outer cover comprises an outer ring cover (6) used for fixing a glove (10) and a glove fixing ring (5) used for fastening transparent glass (2). A first sealing ring (3) is further included, and the first sealing ring (3) is arranged between an inner lining ring (1) and the outer cover in a surrounding mode. A sealing end face (6a) which is extruded to the first sealing ring (3) is arranged at the end of the outer ring cover (6). The glove (10) is pressed and sealed to the end face of the first sealing ring (3). By the adoption of the structure, the structure is simple and reasonable, on-line replacing of the glove is achieved, the working risks of operators are lowered, and the occupational health and safety of the operators are guaranteed.

Description

Gloves apparatus on a kind of isolator and gloves replacing options
Technical field
The present invention relates to sterile operating device, the gloves apparatus specifically on a kind of isolator and gloves are changed
Method.
Background technology
Gloves apparatus is such as applied on so-called isolator in pharmaceuticals industry, and this isolator has and keeps aseptic inner space relative to surrounding environment, is such as filled in container by medicine in this inner space.In order to work in the inner space of process units, use such gloves apparatus, hand is extend into inner space from outside by these gloves apparatus by operating personnel, and can not be contaminated at this.
The enforcement of current new edition GMP, pharmacy corporation software and hardware is had higher requirement, specified in more detail is done to drugs manufacture equipment, has had clear and definite regulation according to Chinese new edition GMP annex 1 Article 13 about the production operation environment without mattress medicine: the operation of high pollution risk should complete in isolator, glove box.And isolator, glove box all must carry out closed-loop operation by the gloves be arranged on gloves ring, personnel and space outerpace and the mutual cross pollution of operating cavity environment can be prevented, to ensure in operating cavity that cleaniliness classs also prevents poisonous and harmful substance in operating cavity from leaking and produces harm to personnel.Be widely used in production and the scientific research field of the industries such as pharmacy, food, chemical industry, electronics, space flight, nuclear industry.
If existing gloves external member finds that in production, experimentation gloves are damaged, leaks, gloves cannot be changed online.Operator need stop ongoing production, experiment operation, unloads gloves ring, extracts the gloves damaged, newer gloves are installed together with gloves ring, fixing.Period, former airtight cavity was opened, operator is exposed in uncontrolled risk environment completely, in chamber, article are also subject to outside contamination, gloves need again to clear up inner chamber after changing, sterilizing, just can proceed after replacement operator to produce, experimental implementation.Along with the development of the relevant laws and regulations such as domestic quality, environmental protection, safety, this gloves ring structure more and more can not meet the actual needs of production, experiment.
For above problem, therefore, be necessary to make improvements.
Summary of the invention
The present invention is to overcome above-mentioned defect of the prior art, provides a kind of good airproof performance, reasonable in design, easy for installation and can realize changing online the device of gloves.
For achieving the above object, the technical solution adopted for the present invention to solve the technical problems is, gloves apparatus on a kind of isolator and gloves replacing options, described isolator comprises casing and at least one gloves apparatus that has chamber, cavity and non-sterile space outerpace separate by casing, and on the sidewall of casing, be provided with at least one action pane, gloves apparatus comprises gloves, interior lining ring and enclosing cover, gloves to be arranged on action pane and can to stretch into gloves hand so that through action pane at chamber operation from space outerpace, described enclosing cover comprises for the outer ring lid of fixing gloves and the gloves retainer plate for fastening clear glass, described outer ring lid is connected with gloves retainer plate by interior hexagonal round head screw, also comprise the first sealing ring, described first sealing ring is arranged between described interior lining ring and enclosing cover around ground, the end of described outer ring lid is provided with the seal face pressing to described first sealing ring, described gloves are pressed against on the end face being sealed in described first sealing ring, described gloves retainer plate is provided with for the first holddown groove of fixing gloves end part seal circle and the second holddown groove for changing new gloves online.
As a preferred embodiment of the present invention, the end of described outer ring lid is step-like, and this step-like step surface is perpendicular to described first sealing ring and directedly install; And described stepped end described gloves are pressed against be sealed in described first sealing ring seal face on.
As a preferred embodiment of the present invention, the end of described outer ring lid is scalene cone, and the first sealing ring end exceeds the installed surface of gloves retainer plate; When outer ring covers, scalene cone end described gloves are pressed against be sealed in described first sealing ring seal face on.
As a preferred embodiment of the present invention, the cross section of described first sealing ring is " L " shape; One end is connected with interior lining ring, and the other end covers with outer ring and is connected.
As a preferred embodiment of the present invention, described first sealing ring is formed with recessed piece; The end of described interior lining ring is formed with protruding block; This protruding block passes through recessed piece of position of extruding first sealing ring, with described outer decorative cover squeeze flow.
As a preferred embodiment of the present invention, described second holddown groove is provided with the 4th sealing ring that gloves carry; 4th sealing ring and gloves one-body molded; Described first holddown groove is provided with the 3rd sealing ring; Described new gloves apparatus is provided with the 5th sealing ring that new gloves apparatus carries.
As a preferred embodiment of the present invention, described first sealing ring is arranged with the inner circumference area of gloves retainer plate with flushing.
As a preferred embodiment of the present invention, described first holddown groove and the second holddown groove are in same plane, and the height of the second holddown groove is higher than the first holddown groove.
As a preferred embodiment of the present invention, described protruding block is arc transition, and the shape of described gloves retainer plate is circular or ellipse.
On a kind of isolator, the gloves replacing options of gloves apparatus comprises the following steps:
Step one: come loose for hexagonal round head screw in fixing gloves retainer plate and outer decorative cover, take off outer decorative cover;
Step 2: removed by the 3rd sealing ring, moves to the first holddown groove position by the 4th sealing ring carried by gloves;
Step 3: new gloves apparatus is carried the position that the 5th sealing ring moves on to the first holddown groove, wrap up from outside by required replacing gloves;
Step 4: unloaded from inside by gloves by new gloves apparatus, the 3rd sealing ring from isolator outside press-in the first holddown groove;
Step 5: interior hexagonal round head screw is tightened in outer decorative cover press-in.
Beneficial effect of the present invention: owing to adopting said structure, have simple and reasonable, achieve the online replacing of gloves, after gloves breakage, by changing gloves online, reduce the possibility of personnel and glove box, the inner cross pollution mutually of isolator to greatest extent.Greatly reduce the work risk of operator, protect the career safety & health of operator.Gloves can proceed normal production, experimental implementation after changing online, do not need to re-start cleaning, sterilizing, displacement to inner chamber, substantially increase operating efficiency, reduce the use cost of equipment.
Accompanying drawing explanation
Fig. 1 is the front view of the embodiment of the present invention one.
Fig. 2 is the A-A sectional view of the embodiment of the present invention one.
Fig. 3 is the B-B sectional view of the embodiment of the present invention one.
Fig. 4 is the gloves retainer plate stereogram of the embodiment of the present invention one.
Fig. 5 is the schematic diagram of the embodiment of the present invention two.
Fig. 6 is that the present invention changes gloves step 1 schematic diagram online.
Fig. 7 is that the present invention changes gloves step 2 schematic diagram online.
Fig. 8 is that the present invention changes gloves step 3 schematic diagram online.
Fig. 9 is that the present invention changes gloves step 4 schematic diagram online.
Figure 10 is that the present invention changes gloves step 5 schematic diagram online.
Reference numeral in figure: interior lining ring 1, clear glass 2, the first sealing ring 3, recessed piece of 3-1, second sealing ring 4, gloves retainer plate 5, outer ring lid 6, seal face 6a, scalene cone 6b, the 3rd sealing ring 7, hexagon socket countersunk flat cap head screw 8, interior hexagonal round head screw 9, gloves 10,4th sealing ring 11, first holddown groove 7a, the second holddown groove 11a, protruding block 1-1, new gloves apparatus 10a, the 5th sealing ring 12.
Detailed description of the invention
Below in conjunction with accompanying drawing, the embodiment of the present invention is elaborated.
Embodiment one:
As Figure 1-4, the present embodiment is gloves apparatus on a kind of isolator and gloves replacing options, isolator comprises casing and at least one gloves apparatus that has chamber, cavity and non-sterile space outerpace separate by casing, and on the sidewall of casing, be provided with at least one action pane, gloves apparatus comprises gloves 10, interior lining ring 1 and enclosing cover, gloves to be arranged on action pane and can to stretch into gloves hand so that through action pane at chamber operation from space outerpace, enclosing cover comprises for the outer ring lid 6 of fixing gloves 10 and the gloves retainer plate 5 for fastening clear glass 2, outer ring lid 6 is connected with gloves retainer plate 5 by interior hexagonal round head screw 9, also comprise the first sealing ring 3, first sealing ring 3 is arranged between described interior lining ring 1 and enclosing cover around ground, the end of outer ring lid 6 is provided with the seal face 6a pressing to described first sealing ring 3, gloves 10 are pressed against on the end face being sealed in the first sealing ring 3, gloves retainer plate 5 is provided with for the first holddown groove 7a of fixing gloves 10 end part seal circle and the second holddown groove 11a for changing new gloves online, enclosing cover comprises the outer ring lid 6 for connecting gloves 10 and the gloves retainer plate 5 for fastening clear glass 2, wherein, clear glass 2 is clamped by gloves retainer plate 5 between the first sealing ring 3 and the second sealing ring 4.At this, interior lining ring 1 is arranged on the inner side of clear glass 2, and gloves retainer plate 5 is arranged on the outer wall of clear glass 2.Gloves 10 are fixed on outer ring lid 6 by the first holddown groove 7a and the second holddown groove 11a.
First holddown groove 7a and the second holddown groove 11a is two holddown grooves, and they are O shape groove, they by gloves 10 the end regions that opens wide be fixed on textural accordingly, the second holddown groove 11a is provided with the 4th sealing ring 11 that gloves 10 carry; 4th sealing ring 11 is one-body molded with gloves 10; Described first holddown groove 7a is provided with the 3rd sealing ring 7; Described new gloves apparatus 10a is provided with the 5th sealing ring 12 that new gloves apparatus 10a carries; By the height of the height of the second holddown groove 11a higher than the first holddown groove 7a, in order to the online replacing of gloves is convenient, new gloves apparatus 10a is changed to from gloves 10, there is difference in height, with new gloves apparatus 10a, damaged gloves 10 are pushed from gloves retainer plate 5, due to self gravitation effect, replacing construction will shorten, and efficiency can increase; Time to arrange the 3rd sealing ring 7 be to change gloves 10 online, by the extruding of the 3rd sealing ring 7, better tightness.
As seen from Figure 3, this device also comprises the first sealing ring 3, shape that cross section is set to " L ";
First sealing ring 3 is arranged on interior lining ring 1, between gloves retainer plate 5 and outer ring lid 6 around ground; First sealing ring 3 is formed with recessed piece of 3-1; The end of described interior lining ring 1 is formed with protruding block 1-1; This protruding block 1-1 passes through recessed piece of 3-1 position of extruding first sealing ring 3, with outer decorative cover 6 squeeze flow, for clamping gloves 10; End and the described gloves 10 of described outer ring lid 6 form step configuration and forming station stepwise cross section on cross section, this step cross-section normal is installed in the first sealing ring 3 is also directed, and described gloves 10 are pressed against on the end face of described first sealing ring 3 by step cross section, and be arc transition by protruding block 1-1, in order to the extruding with the first sealing ring 3, contact area increases, the better effects if of fastening gloves 10.
First sealing ring 3 adopts silica gel plate, the extruding being also provided with protruding block 1-1 and outer decorative cover 6 by the end of interior lining ring 1 ensures that the inner poisonous material of isolator does not bleed D district, " L " shape is arranged to by other first sealing ring 3, step cross section directly and a part contact of gloves 10 and being pressed against on the first sealing ring 3 this glove region, ensure that the seal of whole device.
As preferably, first sealing ring 3 can also select other correspondingly to form, and adopts the sealing surface design of tilting, corresponding, outer decorative cover 6 has the interface formed according to the angle of the first sealing ring 3 equally, and soft gloves 10 can be clamped between which.Structure compact especially can be obtained thus.
First sealing ring 3 flushes at this corresponding inner periphery to outer decorative cover 6 or gloves retainer plate 5, thus obtains and do not disturb step or like this penetrate opening.
Outer ring lid 6 is arranged on the side outwardly of gloves retainer plate 5.This outer ring lid 6 covers gloves retainer plate 5 at this.At this, outer ring lid 6 is fixed on gloves retainer plate 5 by multiple interior hexagonal round head screw 9.
When finding that gloves 10 have breakage to need to change, the gloves replacing options of operating procedure a kind of gloves apparatus as shown in Fig. 6 to Figure 10, comprises the following steps:
Step one: come loose for hexagonal round head screw 9 in fixing gloves retainer plate 5 and outer decorative cover 6, take off outer decorative cover 6;
Step 2: removed by the 3rd sealing ring 7, moves to the first holddown groove 7a position by the 4th sealing ring 11 carried by gloves 10;
Step 3: new gloves apparatus 10a is carried the position that the 5th sealing ring 12 moves on to the first holddown groove 7a, wraps up from outside by required replacing gloves 10;
Step 4: unloaded from inside by gloves 10 by new gloves apparatus 10a, the 3rd sealing ring 7 from isolator outside press-in the first holddown groove 7a;
Step 5: interior hexagonal round head screw 9 is tightened in outer decorative cover 6 press-in.
Embodiment two:
As shown in Figure 5, the end of outer ring lid 6 is formed as scalene cone 6b by the present embodiment, and the first sealing ring 3 end exceeds the installed surface of gloves retainer plate 5; When outer ring lid 6 cover time, scalene cone 6b end described gloves 10 are pressed against be sealed in described first sealing ring 3 seal face on.Be formed with recessed piece of 3-1 by protruding block 1-1 to the first sealing ring 3 to extrude, stress point concentrates on the scalene cone 6b of outer ring lid 6, and contact area increases, and more can ensure the seal of whole device; The other guide of the present embodiment is identical with embodiment one.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Although more to employ in figure lining ring 1 in Reference numeral herein, clear glass 2, the first sealing ring 3, recessed piece of 3-1, second sealing ring 4, gloves retainer plate 5, outer ring lid 6, seal face 6a, scalene cone 6b, the 3rd sealing ring 7, hexagon socket countersunk flat cap head screw 8, interior hexagonal round head screw 9, gloves 10, the 4th sealing ring 11, first holddown groove 7a, the second holddown groove 11a, protruding block 1-1, new gloves apparatus 10a, the 5th term such as sealing ring 12 grade, but do not get rid of the possibility using other term.These terms are used to be only used to describe and explain essence of the present invention more easily; The restriction that they are construed to any one additional is all contrary with spirit of the present invention.

Claims (10)

1. the gloves apparatus on an isolator and gloves replacing options, described isolator comprises casing and at least one gloves apparatus that has chamber, cavity and non-sterile space outerpace separate by casing, and on the sidewall of casing, be provided with at least one action pane, gloves apparatus comprises gloves (10), interior lining ring (1) and enclosing cover, gloves to be arranged on action pane and can to stretch into gloves hand so that through action pane at chamber operation from space outerpace, described enclosing cover comprises outer ring lid (6) and the gloves retainer plate (5) for fastening clear glass (2) for fixing gloves (10), described outer ring lid (6) is connected with gloves retainer plate (5) by interior hexagonal round head screw (9), it is characterized in that: also comprise the first sealing ring (3), described first sealing ring (3) is arranged between described interior lining ring (1) and enclosing cover around ground, the end of described outer ring lid (6) is provided with the seal face (6a) pressing to described first sealing ring (3), described gloves (10) are pressed against on the end face being sealed in described first sealing ring (3), described gloves retainer plate (5) is provided with for first holddown groove (7a) of fixing gloves (10) end part seal circle and the second holddown groove (11a) for changing new gloves online.
2. the gloves apparatus on isolator according to claim 1 and gloves replacing options; It is characterized in that: the cross section of lid (6) end, described outer ring is step cross section, the step surface of this step cross section is perpendicular to described first sealing ring (3) and directedly install; And described step cross section described gloves (10) are pressed against be sealed in described first sealing ring (3) seal face on.
3. the gloves apparatus on isolator according to claim 1 and gloves replacing options; It is characterized in that: the end of described outer ring lid (6) is scalene cone (6b), and the first sealing ring (3) end exceeds the installed surface of gloves retainer plate (5); When outer ring lid (6) cover time, scalene cone (6b) end described gloves (10) are pressed against be sealed in described first sealing ring (3) seal face on.
4. the gloves apparatus on isolator according to claim 1 and gloves replacing options; It is characterized in that: the cross section of described first sealing ring (3) is " L " shape; One end is connected with interior lining ring (1), and the other end covers (6) and is connected with outer ring.
5. the gloves apparatus on isolator according to claim 1 and 2 and gloves replacing options; It is characterized in that: described first sealing ring (3) is formed recessed piece (3-1); The end of described interior lining ring (1) is formed with protruding block (1-1); This protruding block (1-1) by recessed piece of (3-1) position of extruding first sealing ring (3), with described outer decorative cover (6) squeeze flow.
6. the gloves apparatus on isolator according to claim 1 and gloves replacing options; It is characterized in that: described second holddown groove (11a) is provided with the 4th sealing ring (11) that gloves (10) carry; 4th sealing ring (11) is one-body molded with gloves (10); Described first holddown groove (7a) is provided with the 3rd sealing ring (7); Described new gloves apparatus (10a) is provided with the 5th sealing ring (12) that new gloves apparatus (10a) carries.
7. the gloves apparatus on isolator according to claim 1 and 2 and gloves replacing options; It is characterized in that: described first sealing ring (3) is arranged with the inner circumference area of gloves retainer plate (5) with flushing.
8. the gloves apparatus on the isolator according to claim 1 or 4 and gloves replacing options; It is characterized in that: described first holddown groove (7a) and the second holddown groove (11a) are in same plane, and the height of the second holddown groove (11a) is higher than the first holddown groove (7a).
9. the gloves apparatus on isolator according to claim 3 and gloves replacing options; It is characterized in that: described protruding block (1-1) is arc transition, the shape of described gloves retainer plate (5) is circular or ellipse.
10. apply the gloves replacing options of gloves apparatus as claimed in claim 1 for one kind:
Step one: the interior hexagonal round head screw (9) come loose for fixing gloves retainer plate (5) and outer decorative cover (6), takes off outer decorative cover (6);
Step 2: removed by the 3rd sealing ring (7), moves to the first holddown groove (7a) position by the 4th sealing ring (11) carried by gloves (10);
Step 3: new gloves apparatus (10a) is carried the position that the 5th sealing ring (12) moves on to the first holddown groove (7a), wrap up from outside by required replacing gloves (10);
Step 4: unloaded from inside by gloves (10) by new gloves apparatus (10a), the 3rd sealing ring (7) from isolator outside press-in the first holddown groove (7a);
Step 5: interior hexagonal round head screw (9) is tightened in outer decorative cover (6) press-in.
CN201510187286.3A 2015-04-20 2015-04-20 Gloves apparatus on a kind of isolator and gloves replacing method Active CN104786237B (en)

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Application Number Priority Date Filing Date Title
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CN104786237B CN104786237B (en) 2016-06-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109958676A (en) * 2017-12-26 2019-07-02 楚天科技股份有限公司 A kind of flange assembly of sterile gloves
JP7381109B2 (en) 2021-10-27 2023-11-15 万善工機株式会社 Article connection structure

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2590198B1 (en) * 1985-11-20 1990-02-02 Elastotecnnic SHUTTER DEVICE FOR GLOVE BOX
JPH1048388A (en) * 1996-07-31 1998-02-20 Power Reactor & Nuclear Fuel Dev Corp Jig for fixing o-ring and fixing method for o-ring
EP1265257A1 (en) * 2001-06-05 2002-12-11 Extract Technology Limited Containment assembly with gloved access
CN102015224A (en) * 2008-04-28 2011-04-13 罗伯特·博世有限公司 Glove arrangement for production device
CN103624805A (en) * 2013-12-04 2014-03-12 奥星制药设备(石家庄)有限公司 Glove ring capable of realizing online glove replacement
CN203956935U (en) * 2014-08-06 2014-11-26 熊丹 Glove box sealing device
CN104175334A (en) * 2014-08-21 2014-12-03 深圳市华星光电技术有限公司 Operation box and glove replacement method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2590198B1 (en) * 1985-11-20 1990-02-02 Elastotecnnic SHUTTER DEVICE FOR GLOVE BOX
JPH1048388A (en) * 1996-07-31 1998-02-20 Power Reactor & Nuclear Fuel Dev Corp Jig for fixing o-ring and fixing method for o-ring
EP1265257A1 (en) * 2001-06-05 2002-12-11 Extract Technology Limited Containment assembly with gloved access
CN102015224A (en) * 2008-04-28 2011-04-13 罗伯特·博世有限公司 Glove arrangement for production device
CN103624805A (en) * 2013-12-04 2014-03-12 奥星制药设备(石家庄)有限公司 Glove ring capable of realizing online glove replacement
CN203956935U (en) * 2014-08-06 2014-11-26 熊丹 Glove box sealing device
CN104175334A (en) * 2014-08-21 2014-12-03 深圳市华星光电技术有限公司 Operation box and glove replacement method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109958676A (en) * 2017-12-26 2019-07-02 楚天科技股份有限公司 A kind of flange assembly of sterile gloves
JP7381109B2 (en) 2021-10-27 2023-11-15 万善工機株式会社 Article connection structure

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