Gloves apparatus on a kind of isolator and gloves replacing method
Technical field
The present invention relates to sterile operating device, the gloves apparatus on a kind of isolator and gloves are changed specifically
Method.
Background technology
Gloves apparatus is for example applied on so-called isolator in pharmaceuticals industry, and this isolator has with respect to surrounding environment and keeps aseptic inner space, in this inner space, for example medicine is filled in container. In order to work in the inner space of process units, use such gloves apparatus, operating personnel extend into hand inner space from outside by these gloves apparatus, and can be not contaminated at this.
The enforcement of new edition GMP at present, pharmacy corporation software and hardware is had higher requirement, drugs manufacture equipment is done to specified in more detail, had clear and definite regulation according to Chinese new edition GMP annex 1 Article 13 about the production operation environment without mattress medicine: the operation of high pollution risk should complete in isolator, glove box. And isolator, glove box all must carry out closed-loop operation by the gloves that are arranged on gloves ring, can prevent the mutual cross pollution of environment in personnel and space outerpace and operating cavity, ensure the interior cleaniliness classs of operating cavity and prevent that in operating cavity, poisonous and harmful substance leakage produces harm to personnel. Be widely used in production and the scientific research field of the industries such as pharmacy, food, chemical industry, electronics, space flight, nuclear industry.
If existing gloves external member is found gloves breakage, leakage in production, experimentation, cannot change online gloves. Operator need stop ongoing production, experiment operation, unloads gloves ring, extracts the gloves that damage, newer gloves apparatus is installed, fixed together with gloves ring. Former airtight cavity is opened during this time, operator is exposed in uncontrolled risk environment completely, in chamber, article are also subject to outside contamination, gloves after changing, need again to inner chamber clear up, just can proceed to produce after sterilizing, replacement operator, experimental implementation. Along with the development of the relevant laws and regulations such as domestic quality, environmental protection, safety, this gloves ring structure more and more can not meet the actual needs of production, experiment.
For above problem, therefore, be necessary to make improvements.
Summary of the invention
The present invention is in order to overcome above-mentioned defect of the prior art, and a kind of good airproof performance, reasonable in design, easy for installation and can realize the device of online replacing gloves is provided.
For achieving the above object, the technical solution adopted for the present invention to solve the technical problems is, gloves apparatus on a kind of isolator and gloves replacing method, described isolator comprises casing and at least one gloves apparatus with chamber, casing separates cavity and non-sterile space outerpace, and on the sidewall of casing, be provided with at least one action pane, gloves apparatus comprises gloves, interior lining ring and enclosing cover, gloves are arranged on action pane and can hand be stretched into gloves to operate at chamber through action pane from space outerpace, described enclosing cover comprises for the outer decorative cover of fixing gloves with for the gloves retainer plate of fastening clear glass, described outer decorative cover is connected with gloves retainer plate by interior hexagonal round head screw, also comprise the first sealing ring, described the first sealing ring is arranged between described interior lining ring and enclosing cover around ground, the end of described outer decorative cover is provided with the seal face that presses to described the first sealing ring, described gloves are pressed on the end face that is sealed in described the first sealing ring, described gloves retainer plate is provided with for the first holddown groove of fixing gloves end part seal circle with for online the second holddown groove of changing new gloves apparatus.
As a preferred embodiment of the present invention, the end of described outer decorative cover is step-like, and this step-like step surface is perpendicular to described the first sealing ring and directed installation; And described stepped end presses described gloves on the seal face that is sealed in described the first sealing ring.
As a preferred embodiment of the present invention, the end of described outer decorative cover is scalene cone, and the first sealing ring end exceeds the installed surface of gloves retainer plate; In the time that outer decorative cover covers, press described gloves on the seal face that is sealed in described the first sealing ring scalene cone end.
As a preferred embodiment of the present invention, the cross section of described the first sealing ring is " L " shape; One end is connected with interior lining ring, and the other end is connected with outer decorative cover.
As a preferred embodiment of the present invention, described the first sealing ring is formed with recessed; The end of described interior lining ring is formed with protruding block; This protruding block, by recessed position of extruding the first sealing ring, is connected with described outer decorative cover extruding.
As a preferred embodiment of the present invention, described the second holddown groove is provided with the 4th sealing ring that gloves carry; The 4th sealing ring and gloves are one-body molded; Described the first holddown groove is provided with the 3rd sealing ring; Described new gloves apparatus is provided with the 5th sealing ring that new gloves apparatus carries.
As a preferred embodiment of the present invention, described the first sealing ring flushes and arranges with the inner circumference area of gloves retainer plate.
As a preferred embodiment of the present invention, described the first holddown groove and the second holddown groove are in same plane, and the height of the second holddown groove is higher than the first holddown groove.
As a preferred embodiment of the present invention, described protruding block is arc transition, described gloves retainer plate be shaped as circle or ellipse.
On a kind of isolator, the gloves replacing method of gloves apparatus comprises the following steps:
Step 1: come loose for the interior hexagonal round head screw of fixing gloves retainer plate and outer decorative cover, take off outer decorative cover;
Step 2: the 3rd sealing ring is removed, moved to the first holddown groove position by the 4th sealing ring that gloves are carried;
Step 3: new gloves apparatus is carried to the 5th sealing ring and moves on to the position of the second holddown groove, wrap up from outside by required replacing gloves;
Step 4: by new gloves apparatus, gloves are unloaded from inside, the 3rd sealing ring is pressed in the first holddown groove from isolator outside;
Step 5: outer decorative cover is pressed into and tightens interior hexagonal round head screw.
Beneficial effect of the present invention: owing to adopting said structure, have simple and reasonablely, realized the online replacing of gloves, after gloves breakage, by online replacing gloves, personnel and glove box, the inner possibility of cross pollution mutually of isolator are reduced to greatest extent. Greatly reduce operator's work risk, protected operator's occupational health safety. After the online replacing of gloves, can proceed normal production, experimental implementation, not need inner chamber to re-start cleaning, sterilizing, displacement, greatly improve operating efficiency, reduce the use cost of equipment.
Brief description of the drawings
Fig. 1 is the front view of the embodiment of the present invention one.
Fig. 2 is the A-A cutaway view of the embodiment of the present invention one.
Fig. 3 is the B-B cutaway view of the embodiment of the present invention one.
Fig. 4 is the gloves retainer plate stereogram of the embodiment of the present invention one.
Fig. 5 is the schematic diagram of the embodiment of the present invention two.
Fig. 6 is that the present invention changes gloves step 1 schematic diagram online.
Fig. 7 is that the present invention changes gloves step 2 schematic diagram online.
Fig. 8 is that the present invention changes gloves step 3 schematic diagram online.
Fig. 9 is that the present invention changes gloves step 4 schematic diagram online.
Figure 10 is that the present invention changes gloves step 5 schematic diagram online.
Reference numeral in figure: interior lining ring 1, clear glass 2, the first sealing rings 3, recessed 3-1, the second sealing ring 4, gloves retainer plate 5, outer decorative cover 6, seal face 6a, scalene cone 6b, the 3rd sealing ring 7, hexagon socket countersunk flat cap head screw 8, interior hexagonal round head screw 9, gloves 10, the 4th sealing ring 11, the first holddown groove 7a, the second holddown groove 11a, protruding block 1-1, new gloves apparatus 10a, the 5th sealing ring 12.
Detailed description of the invention
Below in conjunction with accompanying drawing, the embodiment of the present invention is elaborated.
Embodiment mono-: as Figure 1-4, the present embodiment is a kind of gloves apparatus and the gloves replacing method on isolator, isolator comprises casing and at least one gloves apparatus with chamber, casing separates cavity and non-sterile space outerpace, and on the sidewall of casing, be provided with at least one action pane, gloves apparatus comprises gloves 10, interior lining ring 1 and enclosing cover, gloves are arranged on action pane and can hand be stretched into gloves to operate at chamber through action pane from space outerpace, enclosing cover comprises for the outer decorative cover 6 of fixing gloves 10 with for the gloves retainer plate 5 of fastening clear glass 2, outer decorative cover 6 is connected with gloves retainer plate 5 by interior hexagonal round head screw 9, also comprise the first sealing ring 3, the first sealing ring 3 is arranged between described interior lining ring 1 and enclosing cover around ground, the end of outer decorative cover 6 is provided with the seal face 6a that presses to described the first sealing ring 3, gloves 10 are pressed on the end face that is sealed in the first sealing ring 3, gloves retainer plate 5 is provided with for the first holddown groove 7a of fixing gloves 10 end part seal circles with for changing online the second holddown groove 11a of new gloves apparatus 10a, enclosing cover comprises outer decorative cover 6 for connecting gloves 10 and the gloves retainer plate 5 for fastening clear glass 2, wherein, clear glass 2 is clamped by gloves retainer plate 5 between the first sealing ring 3 and the second sealing ring 4. at this, interior lining ring 1 is arranged on the inner side of clear glass 2, and gloves retainer plate 5 is arranged on the outer wall of clear glass 2. gloves 10 are fixed on outer decorative cover 6 by the first holddown groove 7a and the second holddown groove 11a.
The first holddown groove 7a and the second holddown groove 11a are two holddown grooves, and they are O shape groove, and they are fixed on end regions unlimited gloves 10 textural accordingly, and the second holddown groove 11a is provided with the 4th sealing ring 11 that gloves 10 carry; The 4th sealing ring 11 is one-body molded with gloves 10; Described the first holddown groove 7a is provided with the 3rd sealing ring 7; Described new gloves apparatus 10a is provided with the 5th sealing ring 12 that new gloves apparatus 10a carries; Height by the height of the second holddown groove 11a higher than the first holddown groove 7a, be for the online replacing of gloves convenient, change to new gloves apparatus 10a from gloves 10, there is difference in height, damaged gloves 10 are pushed from gloves retainer plate 5 with new gloves apparatus 10a, due to self gravitation effect, the replacing time will shorten, and efficiency can increase; The 3rd sealing ring 7 is set is for online when changing gloves 10, by the extruding of the 3rd sealing ring 7, better tightness.
As seen from Figure 3, this device also comprises the first sealing ring 3, and cross section is set to " L " shape;
The first sealing ring 3 is arranged between interior lining ring 1, gloves retainer plate 5 and outer decorative cover 6 around ground; The first sealing ring 3 is formed with recessed 3-1; The end of described interior lining ring 1 is formed with protruding block 1-1; This protruding block 1-1, by recessed 3-1 position of extruding the first sealing ring 3, is connected with outer decorative cover 6 extruding, for clamping gloves 10; The end of described outer decorative cover 6 and described gloves 10 form step structure and form step cross section on cross section, this step cross section is perpendicular to the first sealing ring 3 directed installation, and step cross section is pressed against described gloves 10 on the end face of described the first sealing ring 3, and be arc transition by protruding block 1-1, be for the extruding of the first sealing ring 3, contact area increases, the better effects if of fastening gloves 10.
The first sealing ring 3 adopts silica gel plate, the extruding that is also provided with protruding block 1-1 and outer decorative cover 6 by the end of interior lining ring 1 ensures the inner poisonous material of the isolator D district of not bleeding, other the first sealing ring 3 is arranged to " L " shape, step cross section directly contacts and this gloves region is pressed against on the first sealing ring 3 with a part of gloves 10, has ensured the seal of whole device.
As preferably, the first sealing ring 3 can also select other correspondingly to form, and adopts the sealing surface design of tilting, corresponding, outer decorative cover 6 has the interface forming according to the angle of the first sealing ring 3 equally, and soft gloves 10 can be clamped between them. Can obtain thus compact especially structure.
The first sealing ring 3 flushes with the corresponding inner periphery of outer decorative cover 6 or gloves retainer plate 5 at this, does not disturb step or such opening that penetrates thereby obtain.
Outer decorative cover 6 is arranged on the side of outside sensing of gloves retainer plate 5. This outer decorative cover 6 covers gloves retainer plate 5 at this. At this, outer decorative cover 6 is fixed on gloves retainer plate 5 by multiple interior hexagonal round head screws 9.
In the time finding that gloves 10 have breakage to change, the gloves replacing method of operating procedure a kind of gloves apparatus as shown in Fig. 6 to Figure 10, comprises the following steps:
Step 1: come loose for the interior hexagonal round head screw 9 of fixing gloves retainer plate 5 and outer decorative cover 6, take off outer decorative cover 6;
Step 2: the 3rd sealing ring 7 is removed, moved to the first holddown groove 7a position by the 4th sealing ring 11 that gloves 10 are carried;
Step 3: the position that new gloves apparatus 10a is carried to the 5th sealing ring 12 and move on to the second holddown groove 11a, wraps up from outside by required replacing gloves 10;
Step 4: by new gloves apparatus 10a, gloves 10 are unloaded from inside, the 3rd sealing ring 7 is pressed in the first holddown groove 7a from isolator outside;
Step 5: outer decorative cover 6 is pressed into and tightens interior hexagonal round head screw 9.
Embodiment bis-:
As shown in Figure 5, the end of outer decorative cover 6 is formed as scalene cone 6b by the present embodiment, and the first sealing ring 3 ends exceed the installed surface of gloves retainer plate 5; In the time that outer decorative cover 6 covers, press described gloves 10 on the seal face that is sealed in described the first sealing ring 3 scalene cone 6b end. By protruding block 1-1, the first sealing ring 3 is formed with to recessed 3-1 and pushes, stress point concentrates on the scalene cone 6b of outer decorative cover 6, and contact area increases, and more can ensure the seal of whole device; The other guide of the present embodiment is identical with embodiment mono-.
To the above-mentioned explanation of the disclosed embodiments, make professional and technical personnel in the field can realize or use the present invention. To be apparent for those skilled in the art to the multiple amendment of these embodiment, General Principle as defined herein can, in the situation that not departing from the spirit or scope of the present invention, realize in other embodiments. Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Although more used the interior lining ring 1 of Reference numeral in figure herein, clear glass 2, the first sealing rings 3, recessed 3-1, the second sealing ring 4, gloves retainer plate 5, outer decorative cover 6, seal face 6a, scalene cone 6b, the 3rd sealing ring 7, hexagon socket countersunk flat cap head screw 8, interior hexagonal round head screw 9, gloves 10, the four sealing rings 11, the first holddown groove 7a, the second holddown groove 11a, protruding block 1-1, new gloves apparatus 10a, the 5th sealing ring 12 terms such as grade, but do not get rid of the possibility that uses other term. Use these terms to be only used to describe more easily and explain essence of the present invention; They are construed to any additional restriction is all contrary with spirit of the present invention.