CN104784526A - Traditional Chinese medicine for treating globus hysteriocus and preparation method thereof - Google Patents
Traditional Chinese medicine for treating globus hysteriocus and preparation method thereof Download PDFInfo
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- CN104784526A CN104784526A CN201510151618.2A CN201510151618A CN104784526A CN 104784526 A CN104784526 A CN 104784526A CN 201510151618 A CN201510151618 A CN 201510151618A CN 104784526 A CN104784526 A CN 104784526A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations and particularly relates to a traditional Chinese medicine for treating globus hysteriocus and a preparation method thereof. The traditional Chinese medicine for the treating globus hysteriocus comprises the following main components in parts by weight: 22-28 parts of scaphium scaphigerum, 22-28 parts of honeysuckle, 15-21 parts of radix ophiopogonis, 8-12 parts of liquorice, 22-28 parts of Chinese white olive, 15-21 parts of thunberg fritillary bulb, 6-10 parts of mint, 12-18 parts of rhizoma phragmitis, 15-21 parts of sucrose powder and 1-3 parts of dextrin. The traditional Chinese medicine provided by the invention has the benefits that on one hand, through performing pharmacodynamics research on the traditional Chinese medicine, the traditional Chinese medicine has the effects of reducing sound and clearing throat, diminishing inflammation and alleviating pain, diminishing carbuncle and activating blood; on the other hand, the traditional Chinese medicine is suitable for large-scale production and facilitates the use of more patients due to low cost of various raw materials.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine for the treatment of globus hystericus and preparation method thereof.
Background technology
" globus hystericus " i.e. chronic pharyngitis, refers to the pathological changes caused by pharyngeal chronic infection, is mainly in adult, usually with other bottleneck throat symptoms.Therefore on the books in traditional Chinese medical science books: " globus hystericus person, has obstacles between throat, not out, pharynx not under, the shape person of core is also." primary disease many because of depressed emotion, smoking, anxious state of mind and the pharyngeal drying of onset, scorching hot, swell, itch, blocking etc., but rarer pharyngalgia.Often remove secretions with cough, often spue early morning sticky expectorant block, easily causes nausea.
Current western medicine is mainly based on antibiotic, and western medical treatment pharyngolaryngitis can only temporary transient symptom management, cures the symptoms, not the disease.Long-term taking antibiotic can have side effects, and can cause degradation common adverse reactions under impaired, the body immunity of digestive system, even have the possibility of canceration.Chronic pharyngitis belongs to the traditional Chinese medical science " sore throat " category.By differential diagnosis in tcm, the hyperactivity of deficient fire of pharyngeal chronic congestion, dry pharynx pain is deficiency of body fluid, and pharynx foreign body sensation is that stagnation of phlegm or mental disorder are tied mutually.In treatment to adopt more " tonifying YIN Qingre Liqi. nourishing YIN to lower pathogenic fire heat extraction " principle.To pharyngeally doing, itch, bitterly, foreign body sensation, the excellent such as cough.Treating both the principal and the secondary aspects of a disease at the same time, clinical observation short treating period, has no side effect, safe and reliable, instant effect.But existing treatment by Chinese herbs method mostly is compound decoction, and effective ingredient is run off by fried error, thus reduces drug effect.
Summary of the invention
For the shortcoming of the method about treatment chronic pharyngitis existed now, the invention discloses a kind of Chinese medicine for the treatment of globus hystericus and preparation method thereof.
Particular content of the present invention is: a kind of Chinese medicine for the treatment of globus hystericus, main components in percentage by weight by weight: Semen Sterculiae Lychnophorae 22-28 part, Flos Lonicerae 22-28 part, Radix Ophiopogonis 15-21 part, Radix Glycyrrhizae 8-12 part, Fructus Canarii 22-28 part, Bulbus Fritillariae Thunbergii 15-21 part, core Adiantum monochlamys Eaton. 6-10 part, Rhizoma Phragmitis 12-18 part, cane sugar powder 15-21 part, dextrin 1-3 part.
Optimum ratio is: Semen Sterculiae Lychnophorae 25 parts, Flos Lonicerae 25 parts, Radix Ophiopogonis 18 parts, 10 parts, Radix Glycyrrhizae, Fructus Canarii 25 parts, Bulbus Fritillariae Thunbergii 18 parts, core Adiantum monochlamys Eaton. 8 parts, Rhizoma Phragmitis 15 parts, cane sugar powder 18 parts, 2 parts, dextrin.
In above-mentioned formula: Semen Sterculiae Lychnophorae can clearing away lung-heat again can lung moistening dry therefore be used for the treatment of lung-heat or xeropulmonary cough, play the effect of heat-clearing and toxic substances removing, nourishing the lung to arrest cough, secretion replenishing and throat moistening with compatibility Radix Ophiopogonis; Flos Lonicerae property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil, is equipped with to appoint an Adiantum monochlamys Eaton., and relieving the exterior syndrome is antipyretic, is equipped with Radix Glycyrrhizae sterilization and dispels carbuncle; Fructus Canarii is equipped with Rhizoma Phragmitis, clear larynx profit sound, and the chest stuffiness relieving wets one's whistle; Bulbus Fritillariae Thunbergii heat clearing away is fallen apart carbuncle, relieving cough and resolving phlegm.Adopt the various raw materials of said ratio, that reasonably arranges in pairs or groups and drug effect is played in mixing is more thorough, prevents the counteracting of drug effect between each taste Chinese medicine simultaneously.
The invention has the beneficial effects as follows: on the one hand pharmacodynamic study is carried out to the present invention that there is schwa profit larynx, anti-inflammatory analgesic, the effect of invigorating blood circulation of change carbuncle; On the other hand because the cost of various raw material is lower, be applicable to large-scale production, convenient more patients use.
The preparation technology of this Chinese medicine is:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 75-85 DEG C, and soak time is 1-1.5h, and water consumption is 20-25 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 1.5-2h; Filter, obtain filtrate; Add above-mentioned medical material gross weight 4-6 amount doubly in medicinal residues, carry out second time and decoct, decocting time is 1-1.5h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.35-1.39 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
Adopt above preparation technology mainly according to following reason:
(1) Semen Sterculiae Lychnophorae contains phlegmatic temperament, and in water, swelling degree is comparatively large, decocts altogether, be not easy to the extraction of other medicines effective ingredient with other drug in side; The too high meeting of temperature when simultaneously decocting altogether makes the polysaccharide in Semen Sterculiae Lychnophorae decompose, and therefore adopts the method for the independent warm macerating of Semen Sterculiae Lychnophorae;
(2) all medicines of prescription are mainly containing effective ingredient such as flavonoid, organic acid, alkaloid, saccharide, aminoacid, according to the character of mentioned component, take water boiling and extraction method, in order to make the main component of ingredients fully be extracted by water boiling and extraction method, soak time, the parameters decocted in the preparation technologies such as number of times, decocting time and amount of water are set as above-mentioned each value, make each the effective elements of the medicine obtain extracting the most fully like this, play the maximum effect of drug effect;
(3) sucrose is adjuvant, plays the effect of taste masking.Add a small amount of high aqueous dextrin, not only play adhesive effect but also granule can be made to be dissolved in water rapidly when granule processed.
Pelletize described in the present invention and drying all adopt prior art, the equipment of the equipment adopted also for market can be buied.
Detailed description of the invention
Embodiment 1
Treat the blue or green granule of the fat gold of Chinese medicine of globus hystericus, main components in percentage by weight by weight:
Semen Sterculiae Lychnophorae 25 parts, Flos Lonicerae 25 parts, Radix Ophiopogonis 18 parts, 10 parts, Radix Glycyrrhizae, Fructus Canarii 25 parts, Bulbus Fritillariae Thunbergii 18 parts, core Adiantum monochlamys Eaton. 8 parts, Rhizoma Phragmitis 15 parts, cane sugar powder 18 parts, 2 parts, dextrin.
The preparation method of the Chinese medicine of above-mentioned treatment globus hystericus:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 80 DEG C, and soak time is 1.5h, and water consumption is 23 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 1.5h; Filter, obtain filtrate; Add the amount of above-mentioned medical material gross weight 5 times in medicinal residues, carry out second time and decoct, decocting time is 1h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.37 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
Using method: every day 3 times, be grown up a 6-10 gram, and child reduces by half and takes, and within 7 days, is a course for the treatment of, takes three courses for the treatment of continuously.
Embodiment 2
The present embodiment is a kind of feasible program of embodiment 1, main components in percentage by weight by weight:
Semen Sterculiae Lychnophorae 22 parts, Flos Lonicerae 22 parts, Radix Ophiopogonis 15 parts, 8 parts, Radix Glycyrrhizae, Fructus Canarii 22 parts, Bulbus Fritillariae Thunbergii 15 parts, core Adiantum monochlamys Eaton. 6 parts, Rhizoma Phragmitis 12 parts, cane sugar powder 15 parts, 1 part, dextrin.
The preparation method of the Chinese medicine of above-mentioned treatment globus hystericus:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 85 DEG C, and soak time is 1h, and water consumption is 25 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 2h; Filter, obtain filtrate; Add the amount of above-mentioned medical material gross weight 4 times in medicinal residues, carry out second time and decoct, decocting time is 1-1.5h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.39 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
Embodiment 3
The main components in percentage by weight of the present embodiment is by weight:
Semen Sterculiae Lychnophorae 28 parts, Flos Lonicerae 28 parts, Radix Ophiopogonis 21 parts, 12 parts, Radix Glycyrrhizae, Fructus Canarii 28 parts, Bulbus Fritillariae Thunbergii 21 parts, core Adiantum monochlamys Eaton. 10 parts, Rhizoma Phragmitis 18 parts, cane sugar powder 21 parts, 3 parts, dextrin.
The preparation method of the Chinese medicine of above-mentioned treatment globus hystericus:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 75 DEG C, and soak time is 1.5h, and water consumption is 23 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 1.2h; Filter, obtain filtrate; Add the amount of above-mentioned medical material gross weight 6 times in medicinal residues, carry out second time and decoct, decocting time is 1h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.35 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
Embodiment 4
The main components in percentage by weight of the present embodiment is by weight:
Semen Sterculiae Lychnophorae 23 parts, Flos Lonicerae 23 parts, Radix Ophiopogonis 16 parts, 11 parts, Radix Glycyrrhizae, Fructus Canarii 27 parts, Bulbus Fritillariae Thunbergii 20 parts, core Adiantum monochlamys Eaton. 7 parts, Rhizoma Phragmitis 16 parts, cane sugar powder 18 parts, 2 parts, dextrin.
The preparation method of the Chinese medicine of above-mentioned treatment globus hystericus:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 80 DEG C, and soak time is 1.5h, and water consumption is 23 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 2h; Filter, obtain filtrate; Add the amount of above-mentioned medical material gross weight 5 times in medicinal residues, carry out second time and decoct, decocting time is 1h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.38 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
Comparative example:
Outpatient service be diagnosed as chronic pharyngitis patient 186 example, male 77 example, women 109 example, age characteristics 17-65 year.Random point two groups, wherein treatment group 102 example, matched group 84 example.
Goods obtained by the oral embodiment for the treatment of group, each 10g, every day 3 times; Matched group buccal man yan shu ning pharyngea, 5 balls, 3 times on the one, often organizing equal seven days is a course for the treatment of.
Contrast standard: medication is after 3 days, and dry pharynx, pharyngalgia, cough, foreign body in pharynx sense obviously alleviate, inflammation disappears, and sb.'s illness took a favorable turn is effective.More than 5 days symptoms without alleviation be improved as invalid.
Comparative test result sees the following form:
Clinical observation on the therapeutic effect table
| Effectively | Invalid | Cure rate |
| Treatment group 1 | 99 examples | 3 examples | 97％ |
| Treatment group 2 | 92 examples | 10 examples | 90％ |
| Treatment group 3 | 90 examples | 12 examples | 88％ |
| Treatment group 4 | 97 examples | 5 examples | 95％ |
| Matched group | 72 examples | 12 examples | 86％ |
From upper result, treat the man yan shu ning that four groups of goods taken take than matched group and more effectively can cure globus hystericus, wherein treatment group 1 effect is best.
Claims (5)
1. treat a Chinese medicine for globus hystericus, it is characterized in that: main components in percentage by weight by weight: Semen Sterculiae Lychnophorae 22-28 part, Flos Lonicerae 22-28 part, Radix Ophiopogonis 15-21 part, Radix Glycyrrhizae 8-12 part, Fructus Canarii 22-28 part, Bulbus Fritillariae Thunbergii 15-21 part, core Adiantum monochlamys Eaton. 6-10 part, Rhizoma Phragmitis 12-18 part, cane sugar powder 15-21 part, dextrin 1-3 part.
2. Chinese medicine according to claim 1, is characterized in that: the main components in percentage by weight of described medicine is: Semen Sterculiae Lychnophorae 22 parts, Flos Lonicerae 22 parts, Radix Ophiopogonis 15 parts, 8 parts, Radix Glycyrrhizae, Fructus Canarii 22 parts, Bulbus Fritillariae Thunbergii 15 parts, core Adiantum monochlamys Eaton. 6 parts, Rhizoma Phragmitis 12 parts, cane sugar powder 15 parts, 1 part, dextrin.
3. Chinese medicine according to claim 1, is characterized in that: the main components in percentage by weight of described medicine is: Semen Sterculiae Lychnophorae 28 parts, Flos Lonicerae 28 parts, Radix Ophiopogonis 21 parts, 12 parts, Radix Glycyrrhizae, Fructus Canarii 28 parts, Bulbus Fritillariae Thunbergii 21 parts, core Adiantum monochlamys Eaton. 10 parts, Rhizoma Phragmitis 18 parts, cane sugar powder 21 parts, 3 parts, dextrin.
4. Chinese medicine according to claim 1, is characterized in that: the main components in percentage by weight of described medicine is: Semen Sterculiae Lychnophorae 23 parts, Flos Lonicerae 23 parts, Radix Ophiopogonis 16 parts, 11 parts, Radix Glycyrrhizae, Fructus Canarii 27 parts, Bulbus Fritillariae Thunbergii 20 parts, core Adiantum monochlamys Eaton. 7 parts, Rhizoma Phragmitis 16 parts, cane sugar powder 18 parts, 2 parts, dextrin.
5. a kind of preparation method for the treatment of the Chinese medicine of globus hystericus according to claim 1, is characterized in that: concrete preparation method is:
(1) by the Semen Sterculiae Lychnophorae warm macerating of said ratio, the temperature of immersion is 75-85 DEG C, and soak time is 1-1.5h, and water consumption is 20-25 times of Semen Sterculiae Lychnophorae quality, and soak and terminate rear filtration, filtrate is for subsequent use;
(2), after Flos Lonicerae, Radix Ophiopogonis, Radix Glycyrrhizae, Fructus Canarii, Bulbus Fritillariae Thunbergii, core Adiantum monochlamys Eaton., Rhizoma Phragmitis being mixed according to proportioning, add the water of above-mentioned medical material gross weight 10 times amount, start after soaking 0.5h to decoct, decocting time 1.5-2h; Filter, obtain filtrate; Add above-mentioned medical material gross weight 4-6 amount doubly in medicinal residues, carry out second time and decoct, decocting time is 1-1.5h, filters, obtains filtrate, and twice filtrate merges;
(3) the Semen Sterculiae Lychnophorae filtrate in step 1 must filtrate be mixed homogeneously with step 2, gained filtrate is condensed into thick paste, the relative density 1.35-1.39 of gained thick paste, cane sugar powder, dextrin is added according to proportioning in thick paste, granule is become with No. 2 sieve series after mixing, dry, granulate.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582392A (en) * | 2016-03-14 | 2016-05-18 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating xerostomia |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342312A (en) * | 2008-08-15 | 2009-01-14 | 方向梅 | Medicament for treating pharyngitis and method for preparing the same |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101342312A (en) * | 2008-08-15 | 2009-01-14 | 方向梅 | Medicament for treating pharyngitis and method for preparing the same |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582392A (en) * | 2016-03-14 | 2016-05-18 | 济南正骐生物科技有限公司 | Traditional Chinese medicine for treating xerostomia |
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